TW539547B - Manometer - Google Patents

Abstract

A manometer for continuous measurements uses a sensor made of a piezoelectric material. While conducting a measurement, the sensor is attached to a pulse location such that a blood pressure signal is converted into a voltage signal. The voltage signal is transmitted to an analog/digital converter through a preposition amplifier to be converted into a digital signal. A single chip uses its built-in algorithm to analyze and calibrate the blood pressure value in order to obtain a systolic pressure, a diastolic pressure, and a pulse rate, etc. A display is used to display the blood pressure data. When the blood pressure values are abnormal, an alarm is generated and transmitted to the outside through a communication interface (UART) of the single chip.

Description

539547 \ — -_year month day_correction 丨 Fifth, the description of the invention (1) i [Scope of the invention] | The present invention relates to a sphygmomanometer, in particular a piezoelectric sensor including a pressure sensor attached to a pulse | After transmitting the induction signal to the single chip through the preamplifier and analog / digital converter, the sphygmomanometer that displays the blood pressure and pulse information through the display, and issues a warning when the blood pressure is abnormal, and communicates through the single chip. The interface (UART) is connected to the outside world. [Background of the Invention]

The conduction mechanism of the circulatory system in the heart of the human or animal automatically generates action potentials, which causes the myocardium to shrink and pressurize the blood. It flows through the arterial system to perfuse the capillary system to supply nutrients and oxygen for the operation of various organs and carry waste away. And then collected by the venous system and returned to the heart. The pressure when the heart contracts to output blood is called systolic pressure, and its normal value is about 120 mm-Hg. The pressure when the heart is relaxed is called diastolic pressure, and its normal value is about 80 mm-Hg. Blood pressure measurement is a very important method for diagnosing human health. There are many causes of high blood pressure, which may be vascular disease or kidney disease, and there are many reasons for low blood pressure. One may be ketoacidity caused by dieting and weight loss, which may lead to cardiac palsy. These symptoms are easily overlooked ’but can be fatal when they are severe. The beating of the heart causes the arterial wall to expand / retract simultaneously. When the blood rushes into the aorta from the left ventricle, it ‘impacts the flexible wall’ and forms a wave of pressure that travels along the flow line through the entire arterial system. Although the whole arterial system has pulses, its most noticeable place is the eight parts of the iliac artery near the surface of the human body. 丨 (1) temples, (2) inside of the wrist, (3) inside of the elbow, (4) edge of the neck Side, | (5) the side of the lower jaw, (6) the inner part of the rat's palate, (7) the back of the knee, (8) on the foot

i 539547 MM 89110109 V. Description of the invention (2) | Because the arterial size and environment are similar, they are different. There are many ways to measure blood pressure. The common one is to use an inflatable pressurized beam to tighten the earpiece at the elbow, and then deflate to loosen the girdle, measure the systolic pressure, and continue to deflate. Then the pulse weakens and the diastolic blood pressure is taken in the south. Such sphygmomanometers are listed in the patent publication of the Republic of China: 3 4 1 1 1 5 new and improved structure, 3 3 6 1 6 3 invention patent r patent π wristband inflatable electronic sphygmomanometer, good. Do n’t mention amending the entanglement or other feelings in the hospital for the first time, until the manual type and patent, blood pressure monitor, etc. belong to different parts of the pulse or the arm of the subject in the home. When the detector detects the pulse of mercury, the electronic type when the mercury column is highly ambiguous, such as the pressure reduction of the Chinese manometer 3 2 6 1 5 6

The above-mentioned sphygmomanometer is generally not expensive and usually easy to operate, but it must be decompressed again, so it is inconvenient for occasions that require continuous observation of the patient's blood pressure. In emergency situations such as battlefields and disaster areas, if the injured part is in the arm ', It is not only difficult or impossible to use such sphygmomanometers. Emergency medical staff usually press and hold the victim's carotid artery beating point, and if the pulse is still detected, the blood pressure is still above 50 mm-Hg. Although this method is simple, the implementer must be trained in advance, and the result obtained is an uncertain threshold and should not be used as a medical basis. At present, there are two methods for continuously and surely measuring blood pressure in hospitals: one is to insert a pressure-sensing probe into a blood vessel, so surgery must be performed with unintended risks, and the other is to use blood to pass through a specific feature. The point-of-sound Doppler effect 'must therefore rely on large and precise instruments to receive signals and analyze them

Page 5 2003.01.03. 005 539547 _ Case No. 89110109_ year, month and day V. Explanation of the invention (3). It can be seen that neither is suitable for general applications and is very responsible. In recent years, piezoresistive transducers have been used in many places for sensing pressure, such as various industrial technologies (especially machinery, chemicals, aviation, vehicles, control, etc.), agricultural technology, biotechnology, medical care, and the environment. Monitoring and other fields. Since detailed and many necessary characteristics information has been built and can be directly matched with integrated circuit technology, resistance-sensitive pressure sensors often use silicon crystals as the substrate, and the process includes: pattern transfer (etching), etching, Various microelectronic related technologies such as thin film deposition, ion implantation, etc., need only adjust a certain process parameter, called micromachining, which can create a three-dimensional structure that is integrated with signal processing and control circuits. Detectors and actuators are called Micro-Electro-Mechanical Systems (MEMS). At present, special MEMS technologies such as block micromachining, surface micromachining, lithographic electroplating mold (L 丨 GA), and electric discharge micromachining have been evolved, and the substrate is not limited to silicon crystals ^: Although it is quite thin and short It also has the advantage of reducing costs, but the thickness of the stone tympanic membrane is usually only 2 mm. In the application, the inflatable belt type is still =. Therefore, the seals are required to be sealed, so that the assembly technology and materials are quite expensive. Due to the need to attach an air compression system, it is difficult to compact the overall device ^ 'For example, US Patent Publication No. 4 5 7 8 6 1 3 discloses such a device. [Previous technique] 丨 In a substance with no centrally symmetric atomic arrangement, the = reversible relationship between the stress and the voltage i is called piezoelectricity. : For example, if a stress signal is applied to a single wafer, the phase where the stress is applied can be

20〇3 · 01 · 〇3 · 〇〇6 539547 __Case No. 89110109 I. Explanation of the invention (4) ^ __ Correction; the voltage signal is measured on the surface of the wafer; otherwise, the voltage signal can be measured. Get stress 仏. Since machine inspection and electrical energy can be directly converted, piezoelectric phenomena have been used for a long time in pressure gauges, accelerometers, hydrophones, ultrasound generators, sonars, inkjets, flaw detectors, loudspeakers, and alarms. And other devices. For example, in U.S. Patent Publications: No. 4 5 7 8 6 丨 3 discloses a sound wave sensing device, No. 473 76 7 6 discloses a mechanical parameter measurement device, No. 4838659 discloses a sonar device, and No. 5 1 5 9228 discloses an ultra-sonic sensor. Acoustic wave sensing devices and the like use the piezoelectric principle to make motion elements.

In terms of blood pressure measuring devices, US Patent Publication No. 5303347 proposes to use 70 piezoelectric pieces to sense the pulse, without the need for separate inflatable armbands and sensing wristbands, but still relying on air compression to provide pressure. U.S. Patent Bulletin No. 5 Guan 03 discloses a blood pressure measurement device. The sensor is composed of a piezoelectric piezoelectric diaphragm f between two layers of flexible metal box electrodes. There are seven sensors in total. The middle two / ¼ winding method is constructed in an electrically insulating cover frame. Hood frame: It becomes a cavity to the sensing mink, but it is not necessary to pressurize the cavity with a radon pump. $ When measuring blood pressure ’, one set of sensing is placed on the left and right of the human head or neck = / the mask frame converts the pulse into a voltage signal. The block of the signal processing circuit ^ shows the I left ^ slogan, the left and right logic gates (l0gic gates) generated by the master timing circuit.

f (sequencers), to individually capture the pulse voltage signals from the left and right seven sensed signals respectively; and the pulse voltage signal is input to the display via the filter and amplifier. I Analyze the detailed circuit diagram of US Patent Publication No. 555350 No. 3, not only can you find two drawing errors, but the more serious is the obscurity of the technical idea.

Page 7 2003.01.03. 007 539547, -a_Amendment I. V. Description of Invention (5) | Perhaps in order to overcome the problem of pulse positioning, the patent is equipped with seven sensors in a center / surround manner, but the diameter of the configured mask frame is estimated to be about 5 cm according to the figure, and the range of pulse detection is about} Cm, so in fact, it is possible that only one of the sensors accepts the pulse beat, and the other six are in vain, which is one of its technical ideas. In order to capture the pulse voltage signals from the seven sensors in sequence, the related circuits must use an 8 × i multiplexer and a 4-bit binary counter; moreover, the clock requirements of this counter are controlled manually / automatically. Switching circuit, input 55 5 clock generator or self-controlled clock generator circuit. Yan uses a dominant open circuit to control the shielding end of the multiplexer. It can be seen that the overall circuit required to capture the pulse-related voltage signal is quite large and complicated. Effective, this is the second of its technical ideas. Perhaps in order to suppress high-frequency noise, the patent uses a low-pass filter (10w-P as S fi 11 ers), but although it has a constant pulse rate of 72 times per minute, its waveform can be analyzed by Fourier transform analysis. High-frequency components, so the low-pass filter will inevitably cause serious distortion of the signal. This is the third of its obscure technical ideas. In addition, many other circuits are too cumbersome and should be simplified. [Summary of the Invention] The subject of the present invention is a small sphygmomanometer that is attached to the wrist, skull, neck, etc., and can be detected, and its function is to display the used blood pressure and pulse condition at any time, and Hypertension suspected to be harmful to health = Alert immediately when hypotension. The related device and signal processing method of the present invention are summarized as follows: Pulse pulse sensing device [6]:

Page 8 2003.01.03.008 539547 ΛΆ 89110109 Revision V. Description of the invention (6) Voltage signal, and the device used can be roughly divided into pressure type, differential capacitance type, Hali effect type, etc. 3 f ^, micro knife resistance device selection piezoelectric There are three reasons for the effect type: an additional air compression pump is required; (2) production and ^》, device type Λ Bo · μ, m, and material cost are much higher than other types. Other projects require differential pressure. Field 仏 deals with the circuit [7]: only the field 1 is required to adjust and analyze the voltage signal. The better circuit can be clearly selected. A single chip is required to perform the necessary operations, and ^ interprets f as the expected value, such as systolic pressure. The diastolic blood pressure circuit includes a preamplifier and analog / digital digits to match the power transmission of the pulse sensing device and the gate of the signal processing circuit and amplify the electricity from the pulse sensing device. ii The digital cloud conversion device uses the converted voltage signal as a digital signal required by the single chip to perform the process of type 1. The digital circuit of the preferred circuit of the present invention (1) is easy to use a variety of commercially available devices, such as amplifiers, There are two times: ratio / digital converter, etc. to simplify the circuit and reduce the production ° and early maintenance cost and other requirements, such as systolic blood pressure, increase and decrease blood pressure information such as systolic blood pressure, () pulse count, pulse beat curve, Κ ο r 〇tk 〇ff position, etc. (value m simple device can be easily used for other medical examinations' additional or changed to the engineering field. For example, cancer hard block detection-information display device [$ ": Applicable The information display device includes various liquid crystal displays (Lc, LED, LED display, plasma display panel (PDP), true * emitting light (VFD), electroluminescence (EL) display, field emission display technology (FEf) = device

Page 9 2003.01.03.009 539547 Case No. 89110109 Λ_ Revision 丨 V. Description of the invention (7) | The preferred device selected by the present invention is a monochrome liquid crystal display for two reasons: (1) the use of DC power and power Very low consumption, so you can flexibly choose a small primary battery or accumulator; (2) the operating voltage is consistent with the signal processing circuit

I |, so the power regulation circuit can be omitted; the above reasons should allow the subject matter of the present invention: the overall blood pressure measurement device is miniaturized and easy to wear. —Single-chip programming algorithm (a 1 g 〇 r i t h m): Based on the most economical principle of expected blood pressure items and time, a single-chip programming algorithm for regulating and analyzing voltage signals with a variety of different logics can be written. A preferred step of the single chip program algorithm in the present invention is: (1) confirm that the pressure received by the sensor has reached a measurable range, and confirm that the digital signal input to the single chip has entered a stable state; (2) record This digital signal takes its maximum and minimum values, and calculates the time interval between successive two maximums. The reciprocal of the digital signal is the number of pulses per minute. 0 (3) Perform the following blood pressure value correction method, and convert the maximum values of the items individually. The value and minimum value are the corresponding systolic blood pressure value and diastolic blood pressure value; (4) Output the pulse rate, systolic blood pressure value and diastolic blood pressure value per minute; when the blood pressure value is abnormal, issue a warning and connect with the outside world. (5) Repeat the steps (1). A blood pressure value correction method: According to the principle that the above-mentioned single chip program algorithm requires the most economical time, many different logic blood pressure value correction methods can be written. A preferred step of the blood pressure correction method in the present invention is as follows: (1) a single chip memory, a digital signal is established in advance to correspond to the blood pressure level;

Page 10 2003.01.03.010 539547 _Case No. 89110109_Year Month and Day_ V. Description of the invention (8) Bit reference table, covering the expected blood pressure range; (2) The maximum or minimum value of the digital signal is compared with the reference table To search for the blood pressure level corresponding to the highest and lowest adjacent two terms of the digital signal difference; (3) Select the smaller one of the two blood pressure levels and record the contraction corresponding to the maximum or minimum value of the digital signal Pressure or diastolic pressure. [Schematic description] Figure 1 is a block diagram of a preferred embodiment of the present invention

FIG. 2A is a schematic top view of the structure of a piezoelectric sensor according to a preferred embodiment of the present invention. FIG. 2B is a schematic cross-section of a structure of a piezoelectric sensor according to a preferred embodiment of the present invention. FIG. 3 is a preferred implementation of the present invention. Example signal processing and display circuit diagram. Figure 4 is the single chip calculation program flowchart in Figure 3. Figure 5 is the blood pressure correction calculation program flowchart in Figure 4. [Simplified description of the drawing number] [1] sensor [1 0] lower electrode [ 1 1] Piezoelectric film [1 3] Insulating adhesive | [15] Second printed electric board i [1 7] Conductive perforation of the lower electrode | [1 9] Cavity | [2] Preamplifier [1 2 ] Upper electrode [14] First printed circuit board [1 6] Upper electrode conductive perforation [1 8] Lower electrode pad [20] Resistor

Page 11 2003.01.03.011 539547 — ___j 89110109 Year 5. Description of the invention (9)

Corrected [22] First stage amplifier j [30] Adjusting resistor [32] Resistor [34] Resistor [40] Capacitor [42] Quartz oscillator [2 1] Adjusting resistor 丨 [23] Second stage amplifier i [3] Analog / digital converter | [31] Zener diode I [33] Capacitor 丨 [4] Early chip I [4 1] Capacitor 1 [43] Capacitor [5] Liquid crystal display [7] — 处 1 电 I [Detailed description of the embodiment] FIG. 1 discloses a block diagram of a preferred embodiment of the present invention, including: a pressure sensor [π], a preamplifier [2],-analog / digital conversion ,-LCD display [5]. The user can detect the pulse by pressing or matching the head, neck, etc., and the blood number (pulse beating) is a voltage signal, and the voltage signal is amplified by the value [2], and the voltage signal is amplified, which is more than digital The converter [3] converts it into a digital signal, so that it can be processed according to the built-in program of the single chip = = film = identification ^ mother = pulse, etc. blood pressure information 'and display items also pressure information in the liquid | : Yue Xian not good [5]. When the blood pressure value is abnormal, a warning signal can be issued immediately, and it can be connected to the outside world through a single chip communication interface (UART). ° Figure 2A shows a schematic top view of the structure of a preferred embodiment of the piezoelectric sensor of the present invention, and Figure 2B is a schematic cross-sectional view of the structure. The main parts include: the lower electrode [10], the piezoelectric film [n], Upper electrode u'2] '

Page 12 2003. 01. 〇3 539547 said amendment No. 1 89110109 V. Description of the invention (10) 丨 agent [1 3], the first printed circuit board [1 4], the second printed circuit board [丨 5], upper Electrode conductive perforation [1 6], lower electrode conductive perforation [丨 7], lower electrode pad [18] and cavity [19], among which the lower electrode [1〇], piezoelectric film [u] and upper electrode [1] 2] constitute a piezoelectric element. The liquid crystal display [5] and its driving circuit can be mounted on the upper surface of the second printed circuit board [15], while the preamplifier [2], analog / digital converter [3], single chip [4] and related circuits It can be mounted on the upper surface of the second printed circuit board [15] or the relative positions of the cavities [19] on the upper surface and the lower surface of the second printed circuit board [15] in the most reasonable and space-saving manner, respectively. The lower electrode [10] can be attached to the outer surface of the cavity [19] or attached to the wrist, head, neck, etc. to detect the pulse 胄, so as to sense the condition: = [19] has three functions: ⑴ provides pressure Electrical component vibration space, (2) establish a fixed reference air pressure value; (3) exert resonance effect. [10] There are four material selection conditions: ⑴ is flexible, so the measured part on the right Λ is in close contact to obtain accurate measurement results; it can not be deformed or damaged due to force, such as when it is poisonous (3) It has good adhesion to other materials or processes, excellent adhesion to piezoelectric films, excellent heat resistance in the process of piezoelectric film, etc .; (4) It has chemical i: : Disease = Use long-term skin contact without causing allergic contact: No way: and can be used in any environment and with disinfectants, sweat, etc. =. The lower electrode [1 °] can be selected to meet any of the above requirements, such as: rust, zinc-based, aluminum-based, magnesium-based 'titanium-based, copper-based fluorene. Concerns about item (1) above, and its outer surface may be IU " Suitable organic paint or plastic film.

539547 Γ_89110109_ 年月 日 _ ^ zhengwu, description of the invention (11) how to meet the above conditions of metallization (metaiiize (j) plastic film, such as polycarbonate (pc), polyethylene terephthalate (PET For example, one surface of a thin film such as the trade name Mylar) I uses a technique such as electroless plating, gamma plating, and plasma coating to deposit copper-based, nickel-based, zinc-based metal thin layers. The thickness of the lower electrode [1〇] is based on the principle of not exceeding 15 mm, depending on factors such as design conditions, material selection, manufacturing process, and application occasions.

The metal surface of the lower electrode [10] is partially coated with a piezoelectric film [11], and its shape is covered and is larger than the cavity [19] and the upper electrode conductive perforations [6] are connected to each other. There are four material selection conditions for the piezoelectric film [1 1]: (丨) has excellent piezoelectric characteristics, such as a linear relationship between the output voltage and the applied external force, a high electromechanical coupling coefficient, a very small leakage current, and a low temperature coefficient; (2) It has a pull-back effect, so it can be in close contact with the user's measured part to obtain accurate measurement results; (3) It has mechanical stability, so it can not deform or crack due to long-term acceptance of reciprocating motion; ( 4) It has chemical and crystalline stability, so the fatigue phenomenon is alleviated, that is, it can maintain excellent piezoelectric characteristics after long-term use. Based on the requirements of item (2) above, the piezoelectric film [丨 丨] must not be too thick, but it must not sacrifice voltage output. The piezoelectric film [u] can be selected from ceramic materials or plastic materials; ceramic materials include most of barium titanate (BaT 丨 03) and niobic acid I. (P b N b 2 0J, sharp acid (L i N b 0 3) and other types have spontaneous bipolar junctions | crystals, of which the better is wrong (acid) (PbZr. 45 or abbreviated as PZT) The most practical plastic material is polyvinylidene fluoride (PVDF is simply PVDF). PZT film can be directly applied to the metal surface of the lower electrode [10] by sputtering or screen printing technology. , Its thickness range is 20 to m,

539547 Case No. 891101M V. Description of the invention (12) The better one is Π PVDF thin film, but there are already commercially available products (such as the trade name ^ ynar Piezo-film), and its preferred table name is; thickness is 20. ^ In addition The I PZT powder uses PVDF as an adhesive and uses screen printing technology to form a composite laminated electric thin layer. Its thickness ranges from 5 to 20 μm, preferably about i

| The piezoelectric film [U] is covered with the upper electrode [12], and its manufacturing method can be used for sputtering keys such as 丨 recording copper alloy (thickness controlled at 0.1 m), and screen printing such as Yinsheng | (thickness controlled at 7 ~ 9 # m) or paste, for example, copper cymbal (the thickness is called M m on the table) 'The piezo-electric sensing element constructed by 70% of the lower electrode / piezo film / upper electrode' may have an overall thickness not exceeding 25 // m It is the principle that the maximum piezoelectric effect can be obtained, and it has appropriate flexibility and strength. The above-mentioned piezoelectric sensing element is adhered to the base member bonded by the first printed circuit board [1 4] and the second printed circuit board [1 5] by using an adhesive [丨 3], wherein the first printed circuit board [1 4] Excavate an empty hole with a diameter of about 5mm,

A cavity [ig] is formed after bonding to the first printed circuit board [1 5]. The two printed circuit boards both use hard or soft double-sided boards with copper knots pasted on both sides, and are matched with two hard, two soft, or one soft and one hard, and a number of conductive perforations are formed as required. [16] Conductive perforation with the lower electrode [17]. Before the above-mentioned piezo-sensing element is bonded to the base member, it faces the piezo-inductive element, which is plated with solder in advance and re-f low technology and The upper electrode and the lower electrode form an excellent electrical connection. Only the electrode pads [1 8] are shown in Figure 2. The base member can also be integrally formed by using molded sintered alumina technology, and the thick-film hybrid integrated circuit (thick-fiim hybrid 1C) technology is used to screen print signal processing and display circuits.

Page 15 2003.01.03.015 539547 Case No. 89110109 V. Explanation of the invention (13) Years Figure 2 reveals a better signal processing and display circuit of the present invention. Its power source I supplies 疋 5 V-DC. The test device is expected to be used in a battlefield or emergency field and must be easy to carry, so it is more suitable to use small dry-type primary batteries or accumulators, such as four alkaline manganese batteries or two lithium batteries in series. The voltage signal generated by the piezoelectric sensor [1] is input to the built-in amplifier [2] via the resistor [20], and the preamp [2] is composed of 10-〇 solid = resistor [20], 100 -KW variable resistor [21], the first stage LM324 operational amplifier [22] and the second stage LM324 operational amplifier [23]. The function of the preamplifier [2] has two functions:

Power matching between the piezoelectric sensor [1] and the back-end circuit. The first stage LM324 operational amplifier [22] achieves this voltage signal amplification effect, and its amplification magnification is adjusted by a 100-KΩ variable resistor [2 1] until the segment circuit valley is easy to read and process as in principle. The second-stage LM324 operational amplifier [23] converts the inverting voltage signal output of the first-stage LM324 operational amplifier [22] into a positive voltage signal and sends the positive voltage signal to the analog / digital converter [3]. The best voltage signal output range is go mv ~ 4 V. ·

I ADC0 8 0 4 Analog / digital converter [3] The power supply requirement is 5V-DC

The functions of each terminal are described as follows: The V + terminal [3〇1] and the V- terminal [3 05] are differential input ports for analog signals; because the voltage signal from the preamplifier [2] is not negative Value, the V-terminal [3 0 5] must be grounded beforehand, and the AGND terminal [3 0 6] is analog grounded. The Vref terminal [3 〇2] uses a 4 7 〇-Ω resistor and a 3.9-V Zener diode [31] to form a protection circuit, while the 5 V-DC power supply provides the required voltage and uses a 10-KΩ variable resistor [3〇] cooperate with the above protection

539547 -—: _ Case No. 89110109 — _ year month day __ amendment V. Description of the invention (14) The reference voltage value of the circuit adjustment is 2.56 V. The CLKR terminal [303] and CLK-IN terminal 1 are connected to the clock input, and the charge-discharge effect formed by the 10-KΩ resistor [33] and the 100-pF capacitor [32] oscillates for the operation of the converter Required, and determines that the clock frequency is approximately 1 MHz. After the voltage signal is converted into a digital signal, it is output via the DB0 ~ DB7 bus [307]. Here, the operation mode of the converter [3] is selected: the "high" is at 5 V, and the low, and at 0V, the chip selection signal 0 terminal [3 〇8] must be set to "low" in advance, which is the most convenient The method is to ground it directly. The opposite terminal [3 丨 丨] is the input port of the "analog / digital conversion state" control signal, and the Watson terminal [3 〇9] is inside the π reading data.

The “capacity” control signal bit, and the reverse terminal [3 丨 2] is the “interrupt request” to control the signal bit. The power supply requirement of 8 0 5 1 single chip [4] is also 5V-DC. The functions of each pin are described as follows: at p 丨 · 〇 ～ p 丨 · 7 input port [4 0 1] to accept digital signals 'And in the Po 〇 ~ ρ〇 · 7 output port [4〇7] to send the completion of the processing information. The X 1 terminal [4 0 2] and the X 2 terminal [4 0 3] are connected across the clock stabilization circuit, and the clock stabilization circuit is composed of 13 · 3_MHz quartz oscillators [42] and 20 terminals are connected to each other. -pF capacitor [41] and 20-pF capacitor [43]. Anti-D-end [404]

"'Read data content'" controls the signal bit, while the stomach end [405] is, analog / digital conversion state, and 'control signal bit'. RESE1 ^ [4 06] Connected to a 5 V-DC power supply via a switch via a 20-pF capacitor [40] to restart the system. The INTO terminal [408], T0 terminal [40 9], and T1 terminal [41 1] are the control lines of the LCD display | [5] register, where the ιΝΤ terminal [4〇8] is connected to [5〇2],丨 T0 terminal [4 0 9] is connected to R / W terminal [5 0 3], and T1 terminal [411] is connected to E [5 04]. I Select LCD [5] according to the functional specifications, such as type 202 1

539547 month / day correction

, ______ Case No. 891101M ί * " — ^ | Five 'Invention Description (15) I The tenth sub-line also has a power supply demand of 5 V-DC, and the functions of each terminal are described as follows: · In DB0 ~ DB7 input port [501] accepts scheduled display information. The RS terminal [50 2] is a selection bit for register operation. Among them, 〇, stands for = register, and "1" stands for data register. R / w [5〇3] is When the status of the information read and write bit is "0", the register is executed in cooperation with the ^ terminal [502]. The E terminal [5 0 4] is the read and write bit, and uses the positive of the control signal. The edge is triggered to write sister data in the register. The pulse voltage signal output of the preamplifier [2] is directly connected to the V + terminal [301] of the analog / digital converter [3]; when the converter [3] The Li-end [311] accepts the "transition state" control signal (a low-state pulse with a width greater than 100 ns) from the i-end [4 0 5] on the single chip [4], and the low-order " When the content of the conversion state [3] is cleared, but once again accepts Li Duan [4 0 5], when the conversion state "control signal" is promoted to "high", the analog / digital conversion program is executed. When the converter [ 3] When the analog / digital conversion process is completed, the opposite end [3 0 9] of the single chip U] receives the display [4 04], reads the content, and the control signal becomes "low", then The converted pulse digital signal appears on the DB0 ~ DB7 bus [3 0 7]; at the same time, the INT ^ terminal [3 1 2 accepts the "interrupt request" control signal and becomes "low", "thereby notifying the single chip [ 4] [41 2] bits on P2 · 0 (ie, the 0th bit of input port 2) for its reading procedure. P1 · 0 ~ P1 · 7 input port [4〇1] on the single chip [4] read the pulse digital signals appearing on the DB0 ~ DB7 bus [30 7] on the analog / digital converter [3], and according to the single A pre-set calculation program in chip [4] processes the digital signal of the pulse. See the following and refer to Figure 4 to obtain the corresponding blood pressure value: and pulse number. When the calculation program is processed, the LCD

Page 18: 2003.01.03.018 539547 Case No. 89110109 Rev. V. Description of the invention (16)! [5] The upper RS terminal [5 0 2] accepts the transport from the single chip [4] INTO terminal [4 0 8] The status of the number is "low", and the LCD [5], the upper 1 ^ / \ ^ terminal [5 0 3] also accepts the 丨 single chip [4], the T0 terminal [4 0 9], the transport status ff low. " ; At the same time, the E terminal [5 04] on the liquid crystal display [5] accepts the positive edge of the control signal transmitted by the T1 terminal [411] on the single chip [4], which can cause the DB0 to DB 7 input on the liquid crystal display [5]. [50 1] Accept the clear screen instruction code from the P0 · 0 ~ P〇 · 7 output port [4 0 7] on the single chip [4] to clear the data in its register and reset the display on the screen. When the RS terminal [5 0 2] accepts the status “High”, and the R / W terminal [5〇3] is still in the status “Low”, the E terminal [5 0 4] accepts the τ 1 terminal [4 1 1 again. ] When the positive edge of the control signal is transmitted, DB0 ~ DB7 input 璋 501 on the LCD [5] can be urged to accept ρ〇 · 〇 ～ ρ〇 · 7 output port [4〇7] on the single chip [4] The blood pressure / pulse data is displayed on the screen of the liquid crystal display [5]. The communication interface (UART) of the single chip [4] is composed of the SBUF register and the SC0 register in its special register. The data is transmitted by RXD and TXD is used as the shift pulse during transmission. Its working procedure is: the data scheduled to be transmitted is stored in the SBUF register, and temporarily converted into a register. It is an 8-bit serial data output. When the T1 terminal [411] is in the state '' communication interface (UART), the data is transmitted outward; in the state „〇 " Daily discard, the register is cleared and waiting for the next data. A reveals the calculation process of the single chip [4] in a preferred embodiment of the present invention. The private map includes the following steps: Step [60]: After starting the timer of the single chip [4], the cow is continuously read and recorded. Distinguish the digital signal value from the analog / digital converter [3]; ^ 1] · Confirm whether the pressure value received by the piezoelectric sensor t 1] has reached

Page 19 2003.01.03.019 Case number 89110109

Amendment 539547 V. Description of the invention (17) To the lowest limit that can be measured, I duplicate the step, and invite, 亍 A, above 40mra_Hg, otherwise repeat step i [62]: Compare with the previous amount; Preparation ,, state; within the range, 1 _-Hg, that is, ^^ has been in the relative position between the allowable range of change and the pulse beat ~ 5 weeks of the full pressure inductor 挪 [5 j 上 " systolic pressure " Item — _ until the LCD display step [63J: Find the maximum value of the digital signal ~ and Yixian ^ as its highest value, · The maximum number of digital signal between the main, ', and record consecutive two, calculate the reciprocal of each Mincai 1 = (in minutes) Step ⑽: enter the following blood correction; maximum value Yin 丨 dry * type, convert digital signals;, small value corresponding to systolic blood pressure value and diastolic blood pressure step [6 5 ] ·· From step "6 3 1 medium; ^ μ —, ❹m female minute pulse count and the filling value and diastolic pressure value from ^ of step [64], via single chip [4] [6 $ ΪΪ crystal display [5 ], Then return to step [6] If the voltage value is abnormal, issue a warning, and connect to the outside world through the communication interface (UART) of the single chip [4]. R rg , 4 & shows step L 6 4 in Figure 4] required blood pressure correction calculation subroutine /, 0_private map, including the following steps: Yitian j-column = Z 丨 M]: read the maximum value of the digital signal and Minimum value; "7 1 I · The maximum or minimum value of the digital signal is recorded with the following single chip [4]. The digital signal corresponding to the blood pressure built in the body compares / searches the upper and lower blood pressure reference value with the smallest difference in the blood pressure reference table; Μ] 1 is the smaller of the upper and lower blood pressure reference values with the smallest difference

2003.01.03. 020 539547 V. Description of the invention 00 CJ As soon as possible, the blood pressure value can be transported using the mm-Hg difference method. Both the hose and the device [1] can be seen until the pressure signal value H g is adjusted around the same plastic; In the present invention, the technical improvements in this field should be —1 ^ 89110109 ^ _q day correction (18) — ~ ^ is the corresponding systolic blood pressure value or diastolic blood pressure value. In the memory of film [4], a digital signal correspondence checklist must be established in advance, and its range covers all expected blood pressure values, such as every 'distance from degrees, from 40 mm_Hg to 250 mm-Hg. For any physical use, for example, prepare a plastic water column type sphygmomanometer with a diameter of about 8-cm sealed at both ends and a memory burning device. The piezo-type sensor is placed on the surface of the plastic tube, and the armband of the mercury-type sphygmomanometer is also wrapped around the tube. The pressure of the mercury ball type sphygmomanometer with the adjustment knob is 40 mm-Hg, and then record the 40 mm-Hg and the number generated. Raise 5 mm-Hg each time, repeat the same steps until 250 mm-the digital signal value every 1 mm-Hg gap between them is obtained by interpolation. Although it is explained above in a preferred embodiment, it is not intended to limit the spirit. With the invention entity, it is limited to this embodiment, and the modifications made by the skilled artist without departing from the spirit and scope of the present invention are included in the scope of the patent application described below.

Page 21 2003.01.03.021 539547 Case No. 89110109 Revised diagram Brief description Figure 1 is a block diagram of a preferred embodiment of the present invention: Figure 2A is a top view of the structure of a piezoelectric sensor according to a preferred embodiment of the present invention Schematic 丨 FIG. 2B is a schematic sectional view of the structure of a piezoelectric sensor according to a preferred embodiment of the present invention FIG. 3 is a signal processing and display circuit diagram of a preferred embodiment of the present invention FIG. 4 is a flowchart of a single-chip calculation program in FIG. 3 Figure 5 is a flowchart of the blood pressure correction calculation routine in Figure 4.

Page 22 2003.01.06.022

Claims (1)

:) Out of 547 — ~~ -_m 6. Application for Patent Range 89110109 Modified sphygmomanometer, mainly including 1 · Pulse sensing device, installed to change the sensitivity and convert it into a voltage signal R pulse beat displacement or pressure A signal processing circuit is used to decompose the remote term voltage signal by necessary calculation steps, and executes an information display device for displaying; and pulse information; and 2 pressure and pulse information; can analyze 佶~ Ϊ́ -Pulse 1 does not move: ─ Li A House and Sha Fu Fu 2. — A type of piezoelectric ^ P, mainly including:-the upper electrode and a base structure;--m,-一 屋 i is thin and beautiful ° The lower electrode and the thunder cage ^ are moved and converted into an electrode to form a piezoelectric element, which is used to vibrate the space below the base member; the AP furnace has a two-cavity cavity to provide conductive conduction through the lower electrode of the piezoelectric element. A conductive perforation hole on the upper electrode and a piezo piezo W are also formed to connect the signal processing circuit; the spear uses an insulating adhesive piezo, 1 close to the reference "# 其 Μ · surface, and the piezo pie ML ^ The following table of the base member and the information display device. The electrodes are located in the cavity. The signal processing circuit is assembled on the upper surface of the base member or the bottom surface of the cavity of the body member. Lower electrode ^ 罝, i around item 2 (1) (I disease and can be reduced, strenuous and chemically stable, does not cause skin, aluminum-based, ',' any metal foil, the material is selected from stainless steel Or zinc-based money-based, titanium-based, copper-based alloys; other than stainless steel, this alloy Page 23 2003.01.03. 023 Six, apply for special ^^ — the outer surface of the gold foil adhesive film v.乂 Apply the appropriate organic paint or apply appropriate plastics 4 · According to the patent application, the electrode system has the first 2-cage-disc lesions and can eliminate the primary, secondary, and chemical stability, which does not cause Skin acid ester, polyethylene Any metallized plastic film, the material is selected from the group consisting of polycarbonate coated with vinegar diacetate, etc., and the use of chemical plating, sputtering, etc. 5. Dare to ask J 3 copper base, Secret, zinc-based * metal thin layer. Free from filial piety in the factory-as described in item 11-3-Piezo ji 6. Two = pole 2 thickness should not exceed 15 " m as a principle. ^ "Piezoelectricity-Inductive Device" described in Item 2 of Fan j, in which the second electric film is a material with flexibility, mechanical stability and chemical stability, such as barium titanate (BaTi〇3), niobic acid Ferroelectric crystals of lead (PbNb 20 6), niobium bell (L i NbO 3) and the like, and the preferred one is lead zirconate titanate (PbZruJioD. 7. According to No. 6 of the scope of the patent application, 1 Maoya J: straight The measuring device, wherein the piezoelectric film of the animal is directly applied on the metal surface of the lower electrode by sputtering technology or screen printing technology, and the thickness range is 2 m, preferably 4 A: _n It is 1 0 / zm0 8 · ft according to 1—read _1 company-1 toe wing house shame drama 1 "where the piezoelectric film is a plastic material with flexibility, mechanical stability and chemical stability, such as polydifluoro Vinylidene (PVDF) 'Its preferred thickness is 4 2 0 // m ° 9 · 拫 According to the second patent application of the patent scope-Shixingli ~ 1, where the piezoelectric film is lead zirconate titanate powder to Polydifluoroethylene is beneficial for spotting Page 24 2003.01.03. 024 539547 Case No. 89110109 Amendment VI. The creator of the screen printing technology used in the scope of patent application is 15 # m 〇10. According to the second scope of the patent application, the upper electrode system records the copper alloy deposit. The key is between 0.1 and 0 · 2 / zm. 1 1 · According to the scope of the patent application, the upper electrode series is printed on silver screen printing at 7 ~ 9 / zm 〇12. According to the application patent scope I) Item 2 _ The upper electrode system is coated with copper 羯 at a pressure of 5 / / m. 1 3 According to — .. ηΛ Μ .. 范 —The base member is made of the first printed circuit, wherein the first printed circuit board and the second printed circuit board are bonded to the circuit board using two sides of copper, two hard, two The thickness range of the soft or soft and hard square is 5 ~ 20 // m, preferably the piezoelectric type sensor described above, wherein the thickness of the piezoelectric film is the piezoelectric type described above. The sensor, wherein the thickness of the piezoelectric film is _described_: _House__Huanghuangliying ", where the thickness of the electrical film is better, it is called thick Guiya_: ^ _House electric fan J5I., Wherein the road board and the second printed circuit board are bonded to dig a hollow hole with a diameter of about 5 mm, and then the cavity is formed. The two printed foils are hard or soft double-sided panels, which are matched in a pattern, and a plurality of conductive perforations are formed as required. According to the piezoelectric sensor, the thick-film hybrid integrated circuit and the relevant electric power required for the information display device can be used. 14. According to the patent application No. JI1, the base member is made of alumina sintered body technology. Signal processing circuit. 1 5. The sphygmomanometer according to item 1 of the scope of patent application, wherein the signal processing circuit mainly includes: Page 25 2003.01.03. 025 539547 Case No. 89110109 VI. Patent application scope-A preamplifier for amplifying the piezoelectric sensor, outputting it for the piezoelectric sensor and the rear circuit ^, analog / digital conversion of the electric house signal wheel Device for converting the voltage and power rate matching;, a single chip of digital signal for reading the digital signal, and the blood built-in performance schedule output such as systolic blood pressure, diastolic blood pressure, pulses per minute, etc. are obtained according to the formula The blood pressure information. Pressure information and 16 · According to the sphygmomanometer described in item i 5 of the scope of the patent application, the built-in calculation program on the chip includes the following steps: Among them, the single crystal (1) confirms that the pressure accepted by the sensor has reached b , And confirm that the digital signal of the input single chip has entered the stable range. (2) Record the time interval of the digital signal 'take its maximum value and minimum threshold state' and the second consecutive maximum value, and take its reciprocal as each Minute pulse tens calculation (3) Record the digital signal value '' number within the set time, and find the maximum value and maximum value of the digital signal at the same time. Pulse input per minute: Λ correction calculation subroutine 'to convert the maximum value of the digital signal. The systolic blood pressure value and diastolic blood pressure value (blood pressure value) corresponding to the subtotal value are infused / the anesthesia pulse number and the blood pressure value, and return to step (3); when the blood pressure value is abnormal, a warning is issued and connected with the outside world. 17 • The blood pressure monitor according to item 16 of the scope of the patent application, wherein the single chip taxi has a built-in blood pressure correction calculation subroutine, including the following steps: ~ (1) Read the maximum or minimum value of the digital signal ; The maximum or minimum value of the bit / number is compared with the reference table of the corresponding blood pressure value in the built-in number of the single chip memory, and the upper and lower search for the smallest difference Page 26 2003.01.03. 026 539547 Page 27 2003.01.03. 027