TW252916B - - Google Patents

Info

Publication number
TW252916B
TW252916B TW081102432A TW81102432A TW252916B TW 252916 B TW252916 B TW 252916B TW 081102432 A TW081102432 A TW 081102432A TW 81102432 A TW81102432 A TW 81102432A TW 252916 B TW252916 B TW 252916B
Authority
TW
Taiwan
Prior art keywords
pyrimidyl
pyrazine
group
component selected
erhydro
Prior art date
Application number
TW081102432A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of TW252916B publication Critical patent/TW252916B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Materials For Medical Uses (AREA)
TW081102432A 1991-04-23 1992-03-31 TW252916B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/690,412 US5124346A (en) 1991-04-23 1991-04-23 Synergistic combinations in the treatment of anxiety

Publications (1)

Publication Number Publication Date
TW252916B true TW252916B (zh) 1995-08-01

Family

ID=24772351

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081102432A TW252916B (zh) 1991-04-23 1992-03-31

Country Status (17)

Country Link
US (1) US5124346A (zh)
EP (1) EP0510837B1 (zh)
JP (1) JP2554819B2 (zh)
KR (1) KR960002181B1 (zh)
AT (1) ATE157540T1 (zh)
AU (1) AU634118B1 (zh)
CA (1) CA2066525C (zh)
DE (1) DE69221926T2 (zh)
DK (1) DK0510837T3 (zh)
HU (1) HU216632B (zh)
IE (1) IE921257A1 (zh)
IL (1) IL101626A (zh)
MX (1) MX9201858A (zh)
MY (1) MY109140A (zh)
NZ (1) NZ242429A (zh)
TW (1) TW252916B (zh)
ZA (1) ZA922898B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688518A (en) * 1992-02-27 1997-11-18 Alza Corporation Antidepressive therapy
US5858407A (en) * 1992-02-27 1999-01-12 Alza Corporation Method for administering tandospirone
US5478572A (en) * 1994-09-06 1995-12-26 Bristol-Myers Squibb Co. Gepirone dosage form
FR2746314B1 (fr) * 1996-03-25 1998-06-12 Pf Medicament Produit contenant du milnacipran et de l'idazoxan comme preparation pharmaceutique combinee

Also Published As

Publication number Publication date
KR960002181B1 (ko) 1996-02-13
CA2066525C (en) 1995-05-30
IL101626A0 (en) 1992-12-30
US5124346A (en) 1992-06-23
HUT62796A (en) 1993-06-28
EP0510837A3 (en) 1993-07-28
DK0510837T3 (da) 1997-09-29
MY109140A (en) 1996-12-31
HU216632B (hu) 1999-07-28
ZA922898B (en) 1993-10-22
NZ242429A (en) 1993-08-26
IE921257A1 (en) 1992-11-04
EP0510837A2 (en) 1992-10-28
MX9201858A (es) 1992-10-01
ATE157540T1 (de) 1997-09-15
DE69221926T2 (de) 1998-01-02
DE69221926D1 (de) 1997-10-09
EP0510837B1 (en) 1997-09-03
IL101626A (en) 1996-07-23
HU9201307D0 (en) 1992-07-28
AU634118B1 (en) 1993-02-11
KR920019355A (ko) 1992-11-19
JPH05213742A (ja) 1993-08-24
JP2554819B2 (ja) 1996-11-20

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