TW228526B - - Google Patents

Info

Publication number
TW228526B
TW228526B TW082102974A TW82102974A TW228526B TW 228526 B TW228526 B TW 228526B TW 082102974 A TW082102974 A TW 082102974A TW 82102974 A TW82102974 A TW 82102974A TW 228526 B TW228526 B TW 228526B
Authority
TW
Taiwan
Prior art keywords
beta
heptaalkanoate
cellobioside
pct
tigogenin
Prior art date
Application number
TW082102974A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of TW228526B publication Critical patent/TW228526B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005—Glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW082102974A 1992-06-26 1993-04-19 TW228526B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90559992A 1992-06-26 1992-06-26

Publications (1)

Publication Number Publication Date
TW228526B true TW228526B (zh) 1994-08-21

Family

ID=25421113

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082102974A TW228526B (zh) 1992-06-26 1993-04-19

Country Status (20)

Country Link
US (1) US5606041A (zh)
EP (1) EP0647235B1 (zh)
JP (1) JP2566384B2 (zh)
KR (1) KR950702202A (zh)
AT (1) ATE158299T1 (zh)
AU (1) AU4044293A (zh)
CA (1) CA2138042A1 (zh)
DE (1) DE69314031T2 (zh)
DK (1) DK0647235T3 (zh)
FI (1) FI946082A (zh)
HU (1) HUT68885A (zh)
IL (1) IL106053A0 (zh)
IS (1) IS4039A (zh)
MA (1) MA22913A1 (zh)
MX (1) MX9303824A (zh)
NO (1) NO944999L (zh)
NZ (1) NZ252006A (zh)
TW (1) TW228526B (zh)
UY (1) UY23601A1 (zh)
WO (1) WO1994000479A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2578399B2 (ja) * 1992-06-26 1997-02-05 ファイザー インク． ステロイド−β−Ｏ−セロビオシドヘプタアルカノエートの製造方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2991282A (en) * 1956-10-15 1961-07-04 Rubin Martin Production of hecogenin and tigogenin from plant material
US3303187A (en) * 1965-02-26 1967-02-07 Rubin Martin Recovery of tigogenin acetate and 5alpha-16-pregnene-3beta-ol-20-one from natural plant sources
US3935194A (en) * 1974-01-22 1976-01-27 Omni Research Incorporated Separation of hecogenin-tigogenin mixtures
US3981867A (en) * 1975-03-17 1976-09-21 Beauvoir Max G Process for obtaining sapogenin particularly hecogenin from plant material such as agave sisalana leaves
DE2523284B2 (de) * 1975-05-26 1977-03-24 Nippon Shiny aku Co., Ltd., Kyoto (Japan) Haemostatische, gefaesstabilisierende und antischockmittel
GB2024624A (en) * 1978-07-05 1980-01-16 Roecar Holdings Nv Anti inflammatory spiroketalins
US4254111A (en) * 1978-07-05 1981-03-03 Roecar Holdings (Netherlands Antilles) Nv Sterolin products
US4260603A (en) * 1979-01-02 1981-04-07 Pegel Karl H Sterol glycoside with activity as prostaglandin synthetase inhibitor
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia
SE8203925D0 (sv) * 1982-06-23 1982-06-23 Svenska Sockerfabriks Ab New and novel glycosides, glycoconjugates and processes for their preparation
US4562250A (en) * 1982-09-13 1985-12-31 Regents Of The University Of Minnesota Steroidal glycosides produced by Yucca tissue culture
US5010185A (en) * 1989-06-13 1991-04-23 Pfizer Inc. Processes for tigogenin beta-cellobioside
WO1993011150A1 (en) * 1991-11-25 1993-06-10 Pfizer Inc. Method for making steroidal peracyl glycosides

Also Published As

Publication number Publication date
DE69314031D1 (de) 1997-10-23
EP0647235B1 (en) 1997-09-17
UY23601A1 (es) 1993-11-25
JPH07504920A (ja) 1995-06-01
CA2138042A1 (en) 1994-06-01
DE69314031T2 (de) 1998-01-22
FI946082A0 (fi) 1994-12-23
NO944999D0 (no) 1994-12-23
US5606041A (en) 1997-02-25
MX9303824A (es) 1994-01-31
IL106053A0 (en) 1993-10-20
WO1994000479A1 (en) 1994-01-06
KR950702202A (ko) 1995-06-19
FI946082A (fi) 1994-12-23
MA22913A1 (fr) 1993-12-31
ATE158299T1 (de) 1997-10-15
IS4039A (is) 1993-12-27
JP2566384B2 (ja) 1996-12-25
DK0647235T3 (da) 1997-10-27
NO944999L (no) 1994-12-23
EP0647235A1 (en) 1995-04-12
HUT68885A (en) 1995-08-28
NZ252006A (en) 1995-10-26
AU4044293A (en) 1994-01-24

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