TW202423446A - 用於治療實性瘤之包含 krasg12c 抑制劑及 egfr 抑制劑之組成物及方法 - Google Patents

用於治療實性瘤之包含 krasg12c 抑制劑及 egfr 抑制劑之組成物及方法 Download PDF

Info

Publication number
TW202423446A
TW202423446A TW112142719A TW112142719A TW202423446A TW 202423446 A TW202423446 A TW 202423446A TW 112142719 A TW112142719 A TW 112142719A TW 112142719 A TW112142719 A TW 112142719A TW 202423446 A TW202423446 A TW 202423446A
Authority
TW
Taiwan
Prior art keywords
inhibitor
egfr
methods
compositions
solid tumors
Prior art date
Application number
TW112142719A
Other languages
English (en)
Inventor
瑪麗 安 伊凡杰利斯塔
馬克 安德魯 馬慊
珍妮佛 李 休茲曼
鼎堃 林
史蒂芬 羅伊 朱
桑迪亞 維納亞克 曼德爾卡
Original Assignee
美商建南德克公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美商建南德克公司 filed Critical 美商建南德克公司
Publication of TW202423446A publication Critical patent/TW202423446A/zh

Links

Abstract

本文提供包含 KRas <sup>G12C</sup>抑制劑 (例如，化合物 1) 及 EGFR 抑制劑之組合療法及使用該等組合療法之方法。
TW112142719A 2020-12-08 2021-12-06 用於治療實性瘤之包含 krasg12c 抑制劑及 egfr 抑制劑之組成物及方法 TW202423446A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63/122,702 2020-12-08

Publications (1)

Publication Number Publication Date
TW202423446A true TW202423446A (zh) 2024-06-16

Family

ID=

Similar Documents

Publication Publication Date Title
CR20220258A (es) Inhibidores de kras g12c
EP4268898A3 (en) Kras g12c inhibitors for treating cancer
MX2020012731A (es) Inhibidores de kras g12c y metodos para su uso.
AR111882A1 (es) Inhibidores de kras g12c y métodos para su uso
MX2021005700A (es) Inhibidores de kras g12c y metodos de uso de los mismos.
MX2020011582A (es) Inhibidores de kras g12c y metodos para su uso.
EP4245375A3 (en) Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent
WO2023004102A3 (en) Compositions and methods for inhibition of ras
DK1363900T3 (da) Isoindol-imid-forbindelser, præparater og anvendelser deraf
ZA200005098B (en) Method for stabilizing pharmaceutical compositions by special use of an antioxidant.
BG106054A (en) Pyrazole compositions useful as inhibitors of erk
HK1052934A1 (en) Isoxazoles and their use as inhibitors of erk
MX2020007947A (es) Inhibidores de erbb/btk.
MX2023006690A (es) Procedimientos y composiciones que comprenden un inhibidor de krasg12c y un inhibidor de egfr para el tratamiento de tumores solidos.
MX2022010944A (es) Inhibidores del factor de iniciacion de traduccion eucariotica 4e (eif4e) y sus usos.
MX2023004802A (es) Compuestos espiro heterocíclicos y métodos de uso.
MX2022007442A (es) Inhibidores de la proteina leucemia once-diecinueve (enl)/af9 yeats.
TW202423446A (zh) 用於治療實性瘤之包含 krasg12c 抑制劑及 egfr 抑制劑之組成物及方法
AU1314300A (en) Methods and compositions for inhibiting polymerization of ethylenically unsaturated hydrocarbons
GB0221539D0 (en) Methods of treatment
MX2023005576A (es) Un inhibidor de magl.
ZA202106519B (en) Caspase inhibitors and methods of use thereof
NO983511D0 (no) Difenylstilbener som pro-legemidler for COX-2-inhibitorer
BR112022003584A2 (pt) Compostos de pirrolopirimidina inibidores de perk
PL370361A1 (en) Alkyl urea retinoid agonists i