TW202405013A - 一種抗原結合蛋白及其應用 - Google Patents

一種抗原結合蛋白及其應用 Download PDF

Info

Publication number
TW202405013A
TW202405013A TW112112883A TW112112883A TW202405013A TW 202405013 A TW202405013 A TW 202405013A TW 112112883 A TW112112883 A TW 112112883A TW 112112883 A TW112112883 A TW 112112883A TW 202405013 A TW202405013 A TW 202405013A
Authority
TW
Taiwan
Prior art keywords
antigen
binding protein
seq
amino acid
acid sequence
Prior art date
Application number
TW112112883A
Other languages
English (en)
Chinese (zh)
Inventor
俗俊 鄧
劉培培
顧春銀
王宗達
曹曉丹
楊欣秀
Original Assignee
大陸商上海濟煜醫藥科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 大陸商上海濟煜醫藥科技有限公司 filed Critical 大陸商上海濟煜醫藥科技有限公司
Publication of TW202405013A publication Critical patent/TW202405013A/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
TW112112883A 2022-04-08 2023-04-06 一種抗原結合蛋白及其應用 TW202405013A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2022103817856 2022-04-08
CN202210381785 2022-04-08

Publications (1)

Publication Number Publication Date
TW202405013A true TW202405013A (zh) 2024-02-01

Family

ID=88244096

Family Applications (1)

Application Number Title Priority Date Filing Date
TW112112883A TW202405013A (zh) 2022-04-08 2023-04-06 一種抗原結合蛋白及其應用

Country Status (2)

Country Link
TW (1) TW202405013A (fr)
WO (1) WO2023193767A1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021005594A (es) * 2018-11-13 2021-10-22 Compass Therapeutics Llc Constructos multiespecificos de union contra moleculas de puntos de control y usos de los mismos.
WO2021226984A1 (fr) * 2020-05-15 2021-11-18 三生国健药业(上海)股份有限公司 Anticorps bispécifique tétravalent contre pd-1 et pd-l1

Also Published As

Publication number Publication date
WO2023193767A1 (fr) 2023-10-12

Similar Documents

Publication Publication Date Title
WO2022042690A1 (fr) Anticorps anti-ccr8 et application correspondante
EP4101867A1 (fr) Anticorps bispécifique anti-cd3 et anti-cd123 et son utilisation
CN110856446A (zh) 抗pd-l1抗体及其用途
TWI793395B (zh) 結合pd-l1和ox40的雙特異性抗體
TWI835061B (zh) 抗tnfr2人源化抗體及其用途
WO2023020459A1 (fr) ANTICORPS MONOCLONAL CIBLANT SIRPα ET SON UTILISATION
JP2022514693A (ja) Muc18に特異的な抗体
CA3226441A1 (fr) Anticorps b7-h3 et son utilisation
WO2022079045A1 (fr) Anticorps anti-lilrb et leurs utilisations
WO2024022008A1 (fr) Anticorps monoclonal anti-siglec-15, fragment de liaison à l'antigène et utilisation associée
WO2023046113A1 (fr) Anticorps humanisé anti-pd-l1 humain ou fragment de liaison à l'antigène de celui-ci, et son utilisation
WO2023193767A1 (fr) Protéine de liaison à l'antigène et son application
CN114072175A (zh) 治疗肿瘤的物质和方法
CN113637074A (zh) NKp46抗体及其制备方法和应用
TWI833242B (zh) 抗pd-1人源化抗體或其抗原結合片段、編碼其的核酸、包含其的載體、細胞和藥物組合物及其用途
WO2024032664A1 (fr) Anticorps ciblant pd-l1 et vegf et son utilisation
WO2024032662A1 (fr) Anticorps ciblant pd-1 et vegf, et son utilisation
WO2024103251A1 (fr) Anticorps de type tcr anti-afp/hla02 et son utilisation
TWI833227B (zh) 靶向pd-l1和cd73的特異性結合蛋白及其應用
WO2023109847A1 (fr) Protéine de liaison à l'antigène pd-l1 et son application
WO2024061272A1 (fr) Anticorps anti-pd-l1 et son utilisation
TW202241957A (zh) 抗pd-1抗體及其用途
CN114075284B (zh) Cd47结合分子及其用途
WO2024001641A1 (fr) Anticorps de cd101 et son utilisation
TW202241958A (zh) 抗pd-l1抗體及其應用