TW202402303A - 編碼具持續性活性之環GMP-AMP合成酶之mRNA及用於彼等之脂質遞送載體 - Google Patents

編碼具持續性活性之環GMP-AMP合成酶之mRNA及用於彼等之脂質遞送載體 Download PDF

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TW202402303A
TW202402303A TW112117985A TW112117985A TW202402303A TW 202402303 A TW202402303 A TW 202402303A TW 112117985 A TW112117985 A TW 112117985A TW 112117985 A TW112117985 A TW 112117985A TW 202402303 A TW202402303 A TW 202402303A
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composition
mrna
lipid
antigen
lnp
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TW112117985A
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Chinese (zh)
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艾蜜莉 戈瑟琳
達妮亞 茲凡奇
強納森 周
安娜塔西亞 尼基福羅夫
德布魯 森古普塔
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美商科納療法股份有限公司
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TW112117985A 2022-05-13 2023-05-15 編碼具持續性活性之環GMP-AMP合成酶之mRNA及用於彼等之脂質遞送載體 TW202402303A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202263341987P 2022-05-13 2022-05-13
US63/341,987 2022-05-13
WOPCT/US23/66974 2023-05-12
PCT/US2023/066974 WO2023220746A1 (en) 2022-05-13 2023-05-12 Mrna encoding a constitutively-active cyclic gmp-amp synthase and lipid delivery vehicles for same

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Publication Number Publication Date
TW202402303A true TW202402303A (zh) 2024-01-16

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TW112117985A TW202402303A (zh) 2022-05-13 2023-05-15 編碼具持續性活性之環GMP-AMP合成酶之mRNA及用於彼等之脂質遞送載體

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US (1) US20250255988A1 (enExample)
EP (1) EP4522205A1 (enExample)
JP (1) JP2025516637A (enExample)
KR (1) KR20250023373A (enExample)
CN (1) CN119451694A (enExample)
AU (1) AU2023267834A1 (enExample)
CA (1) CA3256940A1 (enExample)
IL (1) IL316957A (enExample)
TW (1) TW202402303A (enExample)
WO (1) WO2023220746A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025253381A1 (en) * 2024-06-04 2025-12-11 Edity Therapeutics Ltd. Cyclic gmp-amp synthase variants and use thereof
CN121495900B (zh) * 2026-01-13 2026-04-24 泰兴合全药业有限公司 一种环状gmp-amp合成酶突变体及其用于制备2′,3′-环状单磷酸鸟苷-单磷酸腺苷的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3173092B1 (en) * 2015-04-22 2019-06-26 CureVac AG Rna containing composition for treatment of tumor diseases
EP3814487A4 (en) * 2018-06-29 2022-04-20 President and Fellows of Harvard College STRUCTURE OF THE HUMAN CGAS-DNA COMPLEX AND ITS USES
IL298765A (en) * 2020-06-11 2023-02-01 Etherna Immunotherapies Nv Lipid nanoparticles

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AU2023267834A1 (en) 2025-01-02
JP2025516637A (ja) 2025-05-30
CA3256940A1 (en) 2023-11-16
WO2023220746A1 (en) 2023-11-16
EP4522205A1 (en) 2025-03-19
US20250255988A1 (en) 2025-08-14
CN119451694A (zh) 2025-02-14
IL316957A (en) 2025-01-01
KR20250023373A (ko) 2025-02-18

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