TW202201006A - 具備具有作用表面之感測器之設備 - Google Patents
具備具有作用表面之感測器之設備 Download PDFInfo
- Publication number
- TW202201006A TW202201006A TW110118646A TW110118646A TW202201006A TW 202201006 A TW202201006 A TW 202201006A TW 110118646 A TW110118646 A TW 110118646A TW 110118646 A TW110118646 A TW 110118646A TW 202201006 A TW202201006 A TW 202201006A
- Authority
- TW
- Taiwan
- Prior art keywords
- sensor
- flow
- cover
- pump
- flow channel
- Prior art date
Links
- 239000012530 fluid Substances 0.000 claims abstract description 174
- 238000000034 method Methods 0.000 claims abstract description 66
- 238000005286 illumination Methods 0.000 claims abstract description 35
- 230000008878 coupling Effects 0.000 claims abstract description 8
- 238000010168 coupling process Methods 0.000 claims abstract description 8
- 238000005859 coupling reaction Methods 0.000 claims abstract description 8
- 238000006243 chemical reaction Methods 0.000 claims description 101
- 238000001514 detection method Methods 0.000 claims description 26
- 238000012163 sequencing technique Methods 0.000 claims description 22
- 239000003153 chemical reaction reagent Substances 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 16
- 230000009471 action Effects 0.000 claims description 11
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 10
- 238000004891 communication Methods 0.000 claims description 10
- 229910052710 silicon Inorganic materials 0.000 claims description 10
- 239000010703 silicon Substances 0.000 claims description 10
- 239000010409 thin film Substances 0.000 claims description 9
- 230000000295 complement effect Effects 0.000 claims description 6
- 230000001678 irradiating effect Effects 0.000 claims description 6
- 229910044991 metal oxide Inorganic materials 0.000 claims description 6
- 150000004706 metal oxides Chemical class 0.000 claims description 6
- 239000004065 semiconductor Substances 0.000 claims description 6
- 239000000872 buffer Substances 0.000 claims description 5
- 239000012780 transparent material Substances 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 abstract description 15
- 238000004519 manufacturing process Methods 0.000 abstract description 7
- 230000008901 benefit Effects 0.000 description 20
- 230000005284 excitation Effects 0.000 description 17
- 239000000126 substance Substances 0.000 description 16
- 239000000758 substrate Substances 0.000 description 14
- 238000004458 analytical method Methods 0.000 description 10
- 239000002699 waste material Substances 0.000 description 10
- 239000012491 analyte Substances 0.000 description 9
- 239000000523 sample Substances 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 239000000853 adhesive Substances 0.000 description 7
- 230000001070 adhesive effect Effects 0.000 description 7
- 238000010586 diagram Methods 0.000 description 6
- 230000006870 function Effects 0.000 description 5
- 238000003384 imaging method Methods 0.000 description 5
- 239000002773 nucleotide Substances 0.000 description 5
- 125000003729 nucleotide group Chemical group 0.000 description 5
- 108020004414 DNA Proteins 0.000 description 4
- 102000053602 DNA Human genes 0.000 description 4
- 238000004166 bioassay Methods 0.000 description 4
- 239000000109 continuous material Substances 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000012546 transfer Methods 0.000 description 4
- 108091034117 Oligonucleotide Proteins 0.000 description 3
- 238000003556 assay Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000003599 detergent Substances 0.000 description 3
- 230000005670 electromagnetic radiation Effects 0.000 description 3
- 239000000543 intermediate Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 238000001712 DNA sequencing Methods 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 239000010408 film Substances 0.000 description 2
- 239000007850 fluorescent dye Substances 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 1
- 239000002313 adhesive film Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000029918 bioluminescence Effects 0.000 description 1
- 238000005415 bioluminescence Methods 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000001917 fluorescence detection Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- AMGQUBHHOARCQH-UHFFFAOYSA-N indium;oxotin Chemical compound [In].[Sn]=O AMGQUBHHOARCQH-UHFFFAOYSA-N 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000007837 multiplex assay Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000002165 resonance energy transfer Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0332—Cuvette constructions with temperature control
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/042—Caps; Plugs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/168—Specific optical properties, e.g. reflective coatings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7756—Sensor type
- G01N2021/7763—Sample through flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7769—Measurement method of reaction-produced change in sensor
- G01N2021/7786—Fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/022—Casings
- G01N2201/0228—Moulded parts
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Optical Measuring Cells (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062704963P | 2020-06-04 | 2020-06-04 | |
| US62/704,963 | 2020-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW202201006A true TW202201006A (zh) | 2022-01-01 |
Family
ID=78816885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW110118646A TW202201006A (zh) | 2020-06-04 | 2021-05-24 | 具備具有作用表面之感測器之設備 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210379578A1 (https=) |
| EP (1) | EP4162258A4 (https=) |
| JP (1) | JP2023529364A (https=) |
| KR (1) | KR20230030581A (https=) |
| CN (1) | CN115769064A (https=) |
| AU (1) | AU2021284208A1 (https=) |
| CA (1) | CA3177278A1 (https=) |
| TW (1) | TW202201006A (https=) |
| WO (1) | WO2021247266A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220162689A1 (en) * | 2020-11-23 | 2022-05-26 | Qiagen Sciences, Llc | Method and device for sequencing and detecting dna/rna directly on a sensor |
| JP2025533369A (ja) * | 2022-09-29 | 2025-10-07 | イルミナ インコーポレイテッド | 動的光学システム較正 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE403145T1 (de) * | 2000-01-31 | 2008-08-15 | Univ Texas | Tragbare vorrichtung mit einer sensor-array- anordnung |
| DE10036457A1 (de) * | 2000-07-26 | 2002-02-14 | Giesing Michael | Verwendung eines bildgebenden photoelektrischen Flächensensors zur Auswertung von Biochips und Bildgebungsverfahren hierfür |
| ITTO20020808A1 (it) * | 2002-09-17 | 2004-03-18 | St Microelectronics Srl | Dispositivo integrato di analisi del dna. |
| WO2007099736A1 (ja) * | 2006-03-03 | 2007-09-07 | Konica Minolta Medical & Graphic, Inc. | マイクロ検査チップ、光学的検出装置およびマイクロ総合分析システム |
| ES2539421T3 (es) * | 2008-04-04 | 2015-06-30 | Asmag-Holding Gmbh | Sistema de medición de absorción modular |
| US20110312537A1 (en) * | 2010-06-17 | 2011-12-22 | Geneasys Pty Ltd | Loc device for amplifying and detecting target nucleic acid sequences using electrochemiluminescent resonant energy transfer, linear probes with covalently attached primers |
| US10086370B2 (en) * | 2013-02-08 | 2018-10-02 | Infineon Technologies Ag | Microfluidic device and method |
| CA2932916C (en) * | 2013-12-10 | 2021-12-07 | Illumina, Inc. | Biosensors for biological or chemical analysis and methods of manufacturing the same |
| EP3116651B1 (en) * | 2014-03-11 | 2020-04-22 | Illumina, Inc. | Disposable, integrated microfluidic cartridge and methods of making it |
| JP6714603B2 (ja) * | 2015-10-09 | 2020-07-01 | シスメックス株式会社 | 検体処理チップ、検体処理装置および検体処理方法 |
| NL2019043B1 (en) * | 2017-04-25 | 2018-11-05 | Illumina Inc | Sensors having integrated protection circuitry |
| CN111295733B (zh) * | 2017-09-19 | 2024-01-05 | 深圳华大智造科技股份有限公司 | 晶片级测序流通池制造 |
| TWI698638B (zh) * | 2017-12-28 | 2020-07-11 | 美商伊路米納有限公司 | 具有降低的螢光範圍雜訊的檢測器以及用於降低螢光範圍雜訊的方法 |
| TWI685960B (zh) * | 2018-02-03 | 2020-02-21 | 美商伊路米納有限公司 | 使用感測器的主動表面的結構和方法 |
| KR102375602B1 (ko) * | 2018-07-28 | 2022-03-18 | 한국과학기술원 | 모듈형 유체 칩 및 이를 포함하는 유체 유동 시스템 |
| WO2020112327A1 (en) * | 2018-11-26 | 2020-06-04 | Illumina, Inc. | Flow cell systems and methods related to same |
-
2021
- 2021-05-19 US US17/324,363 patent/US20210379578A1/en active Pending
- 2021-05-24 JP JP2022574517A patent/JP2023529364A/ja active Pending
- 2021-05-24 CN CN202180040618.9A patent/CN115769064A/zh active Pending
- 2021-05-24 EP EP21817622.0A patent/EP4162258A4/en active Pending
- 2021-05-24 AU AU2021284208A patent/AU2021284208A1/en active Pending
- 2021-05-24 KR KR1020227045141A patent/KR20230030581A/ko active Pending
- 2021-05-24 WO PCT/US2021/033882 patent/WO2021247266A1/en not_active Ceased
- 2021-05-24 CA CA3177278A patent/CA3177278A1/en active Pending
- 2021-05-24 TW TW110118646A patent/TW202201006A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021247266A1 (en) | 2021-12-09 |
| CA3177278A1 (en) | 2021-12-09 |
| AU2021284208A1 (en) | 2022-12-08 |
| KR20230030581A (ko) | 2023-03-06 |
| EP4162258A1 (en) | 2023-04-12 |
| JP2023529364A (ja) | 2023-07-10 |
| CN115769064A (zh) | 2023-03-07 |
| EP4162258A4 (en) | 2024-10-02 |
| US20210379578A1 (en) | 2021-12-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20240001361A1 (en) | Systems and methods including a rotary valve for at least one of sample preparation or sample analysis | |
| Schumacher et al. | Highly-integrated lab-on-chip system for point-of-care multiparameter analysis | |
| CN107603874B (zh) | 微流控pcr检测系统 | |
| JP2019508669A (ja) | マイクロフルオロメータ、流体システム、およびフローセルラッチクランプモジュールを有する検出装置 | |
| CN107475074B (zh) | 微流控pcr芯片 | |
| JP2011038922A (ja) | 光検出用チップおよび該光検出用チップを用いた光検出装置 | |
| TW202201006A (zh) | 具備具有作用表面之感測器之設備 | |
| EP1561507A1 (en) | System for characterising a fluid, microfluidic device for characterising or analysing concentration components, a method of characterising or analysing such concentrations and a measurement device | |
| KR20210095797A (ko) | 플로우 셀 시스템들 및 이와 관련된 방법들 | |
| US20240009665A1 (en) | Fanout flow cell | |
| US20230130810A1 (en) | Chip for biological analysis, system for biological analysis, and manufacturing method of the chip | |
| CN207294793U (zh) | 微流控pcr检测系统 | |
| US20100248383A1 (en) | Combined optical and electrical sensor cartridges | |
| CN111157731B (zh) | 基于cmos图像传感的光波导多微流道检测系统 | |
| HK40089403A (zh) | 具有带有源表面的传感器的装置 | |
| CN207276595U (zh) | 微流控pcr芯片 | |
| CN111157729B (zh) | 基于cmos图像传感的光波导微流体检测系统 | |
| RU2791650C2 (ru) | Картридж для проведения биохимических реакций | |
| Perdigones Sánchez et al. | Optical Detection Techniques for Biomedical Sensing: A Review of Printed Circuit Board (PCB)-Based Lab-on-Chip Systems | |
| US20220080414A1 (en) | Fluid analysis with channels formed in lids | |
| HK40012117A (en) | Systems and methods for biochemical analysis including a base instrument and a removable cartridge | |
| HK1235735A1 (en) | Systems and methods including a rotary valve for at least one of sample preparation or sample analysis | |
| HK1235735B (en) | Systems and methods including a rotary valve for at least one of sample preparation or sample analysis | |
| CN113454776A (zh) | 模块化和平铺式光学传感器 | |
| KR20060038543A (ko) | 전면 발광 광원을 이용한 랩온어칩 |