TW202124726A - 診斷染色體標記 - Google Patents

診斷染色體標記 Download PDF

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TW202124726A
TW202124726A TW109131199A TW109131199A TW202124726A TW 202124726 A TW202124726 A TW 202124726A TW 109131199 A TW109131199 A TW 109131199A TW 109131199 A TW109131199 A TW 109131199A TW 202124726 A TW202124726 A TW 202124726A
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阿洛爾 賽爾凡 瑞瑪達斯
伊旺 杭特
艾力山卓 阿考里特雀夫
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英商牛津生物力學公眾有限公司
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Abstract

本發明提供一種用於分析與泛自閉症障礙預後相關的染色體區域及相互作用的方法。

Description

診斷染色體標記
本發明係關於疾病標記。
咸信泛自閉症障礙(ASD)與基因及環境因素之組合相關。風險因數包括某些感染、毒素、自體免疫疾病、古柯鹼及空氣污染物。在全球範圍內，據估計自閉症影響2480萬人(2015年估計)。在發達國家中，幾乎1.5%之兒童經診斷患有ASD (2017年估計)。此速率根據2000年估計顯著增加0.7%。
本發明係基於以下發現：使用染色體構形標籤來量測如在替代全身性剖析中偵測到的3D基因體架構中之全身性顯著差異，其能夠鑑別對泛自閉症障礙(ASD)及不同形式之ASD具有特異性之散佈個別染色體構形。
因此，本發明提供一種用於偵測代表群體中之子群之染色體狀態的方法，其包含判定與該染色體狀態相關之染色體相互作用存在或不存在於基因體之經限定區域內；及 -  其中該染色體相互作用已視情況藉由判定哪些染色體相互作用與對應於該群體之該子群之染色體狀態相關的方法來鑑別，該方法包含使來自具有不同染色體狀態之子群之第一組核酸與第二組索引核酸接觸，且允許互補序列雜交，其中該第一組核酸及該第二組核酸中之該等核酸代表經接合產物，該經接合產物包含來自在染色體相互作用中聚集在一起的兩個染色體區域的序列，且其中該第一組核酸與該第二組核酸之間的雜交圖案允許判定哪些染色體相互作用對該子群具有特異性；及 -  其中該子群與泛自閉症障礙(ASD)的預後相關且該染色體相互作用： (i)     存在於表1、表2、表3或表4中之任一者中所列之區域或基因中之任一者中；及/或 (ii)    對應於由表1、表2、表3或表4中之任一者中所示之任何探針所代表的染色體相互作用中之任一者，及/或 (iii)   存在於包含或側接(i)或(ii)之4,000個鹼基區域中。
此外，本發明提供一種用於鑑別ASD之預後的方法，其包含判定如表1、表2、表3或表4中之任一者中所代表的染色體相互作用存在或不存在，由此判定預後。在一個態樣中，本發明提供一種用於鑑別ASD之預後的方法，其包含判定如表8、表9或表10中之任一者中所代表的染色體相互作用存在或不存在，由此判定預後。本發明亦提供一種用於鑑別ASD之預後的方法，其包含判定如由本文中之表中之任一者所代表的染色體相互作用存在或不存在，由此判定預後。
本發明之態樣 本發明係關於判定ASD之預後，包括關於ASD之嚴重程度及/或類型係侵襲性的抑或惰性的。此判定係藉由例如在各表中之任一者中對本文揭示之相關標記中之任一者、或標記之較佳組合或本文揭示之經限定特定區域中之標記進行分類來進行。因此，本發明係關於一種對個體進行分類以判定ASD狀態的方法，例如以診斷ASD或ASD之類型，或以判定ASD之預後或ASD之類型。
基本上，在本發明之方法中，藉由對標記進行分類來鑑別出ASD之亞群。因此，舉例而言，本發明係關於與ASD預後相關的一組表觀遺傳標記。因此，本發明允許向患者給予準確地反映患者之需求的個人化療法。可基於分類之結果向個體投與本文中提及之任何療法(例如，藥物)。因此，可實施本發明之方法以選擇用於醫療治療的個體。
較佳地，在方法中分類的標記為由各表中之探針或引子序列所代表的彼等標記。
本發明之方法 本發明之方法包含用於偵測與預後相關之染色體相互作用的分類系統。可使用本文中提及的基於在染色體相互作用中聚集在一起的染色體之交聯區域的EpiSwitch™系統，使染色體DNA裂解且接著接合存在於交聯實體中之核酸以獲得具有來自形成染色體相互作用之兩個區域的序列的經接合核酸來執行此分類。此經接合核酸之偵測允許判定存在或不存在特定染色體相互作用。
可使用其中使用第一核酸及第二核酸之群體的上述方法來鑑別染色體相互作用。亦可使用EpiSwitch™技術產生此等核酸。
與本發明相關的表觀遺傳相互作用 如本文中所使用，術語『表觀遺傳』及『染色體』相互作用通常係指染色體之遠端區域之間的相互作用，該等相互作用為動態的且依據染色體之區域之狀態而改變、形成或破裂。
在本發明之特定方法中，通常藉由首先產生經接合核酸來偵測染色體相互作用，該經接合核酸包含來自作為相互作用之部分的兩個染色體區域的序列。在此類方法中，區域可藉由任何適合的手段交聯。在一較佳態樣中，相互作用係使用甲醛交聯，但亦可利用任何醛或D-生物素-e-胺基己酸-N-羥基丁二醯亞胺酯或地高辛-3-O-甲基羰基-e-胺基己酸-N-羥基丁二醯亞胺酯交聯。對甲醛可交聯相隔4埃的DNA鏈。較佳地，染色體相互作用係在相同染色體上且視情況相隔2至10埃。
染色體相互作用可反映染色體之區域之狀態，例如，其回應於生理條件之變化是進行轉錄還是受到抑制。已發現對如本文所定義之子群組具有特異性的染色體相互作用為穩定的，因此提供量測兩個子群組之間的差異的可靠方式。
另外，對特徵(諸如預後)具有特異性的染色體相互作用將通常在生物過程的早期發生，例如相較於其他表觀遺傳標記，諸如甲基化或組蛋白蛋白質結合之變化。因此，本發明之方法能夠偵測生物過程之早期階段。此允許可因此更有效的早期干預(例如，治療)。染色體相互作用亦反映個體之當前狀態且因此可用於評定預後之變化。另外，在相同子群組內的個體之間的相關染色體相互作用中存在極少變化。偵測染色體相互作用具有很高的資訊性，其中每個基因具有至多50種不同的可能相互作用，且因此本發明之方法可查詢500,000種不同的相互作用。
染色體相互作用與基因標記或其他類型之表觀遺傳標記(諸如甲基化)之間不存在一對一對應關係。因此，染色體相互作用代表單獨的調節模態。
較佳的標記集合 在本文中，術語『標記』或『生物標記』係指可在本發明中偵測(分類)的特定染色體相互作用。本文揭示特定標記，其中之任一者可用於本發明中。可例如在本文揭示之組合或數字中使用另外的標記集合。揭示於本文之表中的特定標記為較佳的以及存在於本文之表中提及之基因及區域中之標記為較佳的。此等可藉由任何適合方法進行分類，例如本文揭示之基於PCR或探針之方法，包括qPCR方法。本文中藉由定位或藉由探針及/或引子序列來限定標記。
染色體相互作用之位置及起因 染色體相互作用可重疊且包括經展示以編碼相關或未描述基因之染色體區域，但同樣可在基因間區域中。另外應指出，本發明人發現所有區域中之表觀遺傳相互作用在判定染色體基因座之狀態中同樣重要。此等相互作用未必在位於基因座之特定基因之編碼區域中且可在基因間區域中。
在本發明中偵測到的染色體相互作用可因環境因素、DNA甲基化、非編碼反義RNA轉錄物、非突變致癌物、組蛋白修飾、染色質重構及特定局部DNA相互作用而受底層DNA序列之變化影響。引起染色體相互作用的變化可受底層核酸序列之變化影響，該等變化本身不直接地影響基因產物或基因表現之模式。此類變化可為例如基因內及/或基因外之SNP、基因間DNA之基因融合及/或缺失、微RNA及非編碼RNA。舉例而言，眾所周知，大約20%之SNP在非編碼區域中，且因此如所描述之方法在非編碼情形中亦具有資訊性。在一個態樣中，聚集在一起以形成相互作用的染色體區域小於5 kb、3 kb、1 kb，在相同染色體上相隔500個鹼基對或200個鹼基對。
偵測到的染色體相互作用較佳在表1、表2、表3或表4中之任一者中提及的基因中之任一者內。然而，其亦可在基因之上游或下游，例如距基因之上游或下游或距編碼序列至多50,000、至多30,000、至多20,000、至多10,000或至多5000個鹼基。
子群組、時間點及個人化治療 在一個態樣中，本發明判定預後。此可能在一或多個經限定時間點處，例如在至少1、2、5、8或10個不同的時間點處。至少1、2、5或8個時間點之間的持續時間可為至少5、10、20、50、80或100天。
如本文中所使用，「子群組」較佳係指群體子群組，更佳為特定動物(諸如特定真核生物)或哺乳動物(例如，人類、非人類、非人類靈長類或嚙齒動物，例如小鼠或大鼠)之群體中之子群組。最佳地，「子群組」係指人類群體中之子群組。
本發明包括偵測且治療群體中之特定子群組。本發明人發現，染色體相互作用在給定群體中之子組(例如，至少兩個子組)之間不同。鑑別此等差異將允許醫師將其患者分類為群體之一個子組之一部分，如方法中所描述。因此，本發明向醫師提供一種基於患者之表觀遺傳染色體相互作用將患者之藥品個人化的方法，例如藥物之類型及/或其劑量及/或其投藥頻率。
本發明係關於在ASD之廣泛定義內出現的任何特定病況。在一個態樣中，病況為自閉症或兒童自閉症。病況可為亞斯伯格症候群(Asperger's syndrome)、PDD-NOS (廣泛性發展障礙(Pervasive Development Disorder))或兒童崩解症。本發明係關於任何PDD-NOS病況，包括成癮病況，諸如對物質或數位媒體裝置成癮。ASD EpiSwitch標記揭示成癮路徑、軸突蛋白(neuroxin)及神經配蛋白(neuroligin)調節之路徑、雌激素信號傳導、TH17分化及NK細胞調節、Hippo、IL4及IL13調節、HPV感染及mTOR信號傳導中的表觀遺傳失調及調節性缺陷。
產生經接合核酸 本發明之某些態樣利用經接合核酸，特定言之經接合DNA。此等核酸包含來自以染色體相互作用聚集在一起且因此提供關於相互作用之資訊的兩個區域的序列。本文描述之EpiSwitchTM 方法使用此類經接合核酸之產生來偵測染色體相互作用。
因此，本發明之方法可包含藉由以下步驟(包括包含此等步驟之方法)產生經接合核酸(例如，DNA)的步驟： (i)     較佳地活體外交聯在染色體基因座處存在的表觀遺傳染色體相互作用； (ii)    視情況自該等染色體基因座分離經交聯DNA； (iii)   例如藉由用切割至少一次之酶(特定言之，在該等染色體基因座內切割至少一次之酶)進行限制性消化而將該經交聯DNA切割； (iv)   接合該等經交聯裂解DNA末端(特定言之以形成DNA環)；及 (v)    視情況鑑別該經接合DNA及/或該等DNA環之存在，特定言之使用諸如PCR (聚合酶鏈反應)之技術，以鑑別特定染色體相互作用之存在。
可實施此等步驟以針對本文中提及之任何態樣偵測染色體相互作用。亦可實施該等步驟以產生本文中提及之第一組及/或第二組核酸。
PCR (聚合酶鏈反應)可用於偵測或鑑別經接合核酸，例如所產生之PCR產物之大小可指示存在的特定染色體相互作用，且可因此用於鑑別基因座之狀態。在較佳態樣中，至少1、2或3個如表5中所示之引子或引子對用於PCR反應。在其他態樣中，至少1、10、20、30、50或80個如表1、表2、表3或表4中所示之引子或引子對用於PCR反應。熟習此項技術者將知曉可用於切割所關注染色體基因座內之DNA的眾多限制酶。顯而易見，所使用之特定酶將視所研究之基因座及位於其中之DNA序列而定。可用於切割如本發明所描述之DNA的限制酶之非限制性實例為TaqI。
EpiSwitchTM 技術 EpiSwitchTM 技術亦與微陣列EpiSwitchTM 標記資料在偵測對表型具有特異性之表觀遺傳染色體構形標籤中的用途相關。以本文描述之方式利用經接合核酸的態樣(諸如EpiSwitchTM )具有若干優點。其具有低水準之隨機雜訊，例如此係因為來自本發明之第一組核酸的核酸序列與第二組核酸雜交或未能與第二組核酸雜交。此提供允許以相對簡單的方式在表觀遺傳水準下量測複雜機制的二進位結果。EpiSwitchTM 技術亦具有快速處理時間及較低成本。在一個態樣中，處理時間為3小時至6小時。
樣品及樣品處理 本發明之方法將通常在樣品上實施。可在限定時間點處，例如在本文中所定義之任何時間點處獲得樣品。樣品將通常含有來自個體之DNA。其將通常含有細胞。在一個態樣中，樣品係藉由最小創傷性方式獲得且可例如為血液樣品。DNA可經提取且用標準限制酶切碎。此可預判定哪些染色體構形將保留且將用EpiSwitchTM 平台偵測到。由於組織與血液之間的染色體相互作用同步(包括水平轉移)，血液樣品可用於偵測組織(諸如與疾病相關之組織)中之染色體相互作用。
本發明核酸之特性 本發明係關於某些核酸，諸如本文中描述為在本發明之方法中使用或產生的經接合核酸。此等核酸可與本文中提及之第一核酸及第二核酸相同或具有本文中提及之第一核酸及第二核酸之特性中之任一者。本發明之核酸通常包含兩個各自包含來自以染色體相互作用聚集在一起的兩個染色體區域中之一者的序列的部分。通常，各部分的長度為至少8、10、15、20、30或40個核苷酸，例如長度為10至40個核苷酸。較佳的核酸包含來自各表中之任一者提及的基因中之任一者的序列。通常，較佳的核酸包含表1、表2、表3或表4中提及之特定探針序列；或此類序列之片段及/或同源物。
較佳地，核酸為DNA。應瞭解，在提供特定序列時，本發明可視需要在特定態樣中使用互補序列。
表1、表2、表3或表4中之任一者中所示的引子亦可如本文中所提及用於本發明中。在一個態樣中，使用包含以下中之任一者的引子：表1、表2、表3或表4中所示之序列；或表1、表2、表3或表4中所示之任何序列之片段及/或同源物。
『 第一 』 核酸及 『 第二 』 核酸 在本發明之一個態樣中： -  第二組核酸來自比第一組核酸更大的個體群組；及/或 -  第一組核酸來自至少8位個體；及/或 -  第一組核酸來自至少4個來自第一子群組之個體及至少4個來自第二子群組之個體，該第二子群組較佳地不與第一子群組重疊。
在本發明之另一態樣中： -  第二組核酸代表未經選擇群組；及/或 -  其中第二組核酸結合於限定位置處之陣列；及/或 -  其中第二組核酸代表最少100個不同基因中之染色體相互作用；及/或 -  其中第二組核酸包含代表至少1,000種不同染色體相互作用之至少1,000個不同核酸；及/或 -  其中第一組核酸及第二組核酸包含至少100個長度為10至100個核苷酸鹼基之核酸。
第二組核酸 - 『索引』序列 第二組核酸序列具有作為一組索引序列之功能，且基本上為適合於鑑別子群組特定序列之一組核酸序列。其可代表『背景』染色體相互作用且可以一些方式經選擇或未經選擇。其通常為所有可能的染色體相互作用之子組。
第二組核酸可藉由任何適合方法獲得。其可以計算方式獲得或其可基於個體中之染色體相互作用。其通常地代表比第一組核酸更大的群體群組。在一個特定態樣中，第二組核酸代表一組特定基因中之所有可能的表觀遺傳染色體相互作用。在另一特定態樣中，第二組核酸代表存在於本文描述之群體中的較大比例之所有可能表觀遺傳染色體相互作用。在一個特定態樣中，第二組核酸代表至少50%或至少80%的至少20、50、100或500個基因，例如20至100或50至500個基因中的表觀遺傳染色體相互作用。
第二組核酸通常代表至少100種改變、調節或以任何方式介導群體中之表型的可能表觀遺傳染色體相互作用。第二組核酸可代表影響物種之疾病狀態(通常與診斷或預後相關)的染色體相互作用。第二組核酸通常包含代表與預後子群組相關及無關的表觀遺傳相互作用的序列。
在一個特定態樣中，第二組核酸至少部分地來源於群體中之天然存在之序列，且通常藉由電腦模擬(in silico )方法獲得。相較於存在於天然存在之核酸中的核酸之一對應部分，該等核酸可進一步包含單一或多個突變。突變包括一或多個核苷酸鹼基對之缺失、取代及/或添加。在一個特定態樣中，第二組核酸可包含代表與存在於天然存在之物種中的核酸之對應部分具有至少70%序列一致性之同源物及/或直系同源物的序列。在另一特定態樣中，提供與存在於天然存在之物種中的核酸之對應部分具有至少80%序列一致性或至少90%序列一致性。
第二組核酸之特性 在一個特定態樣中，在第二組核酸中存在至少100種不同的核酸序列，較佳至少1000、2000或5000種不同的核酸序列，至多100,000、1,000,000或10,000,000種不同的核酸序列。典型數目將為100至1,000,000，諸如1,000至100,000種不同的核酸序列。所有或至少90%或至少50%或此等核酸將對應於不同的染色體相互作用。
在一個特定態樣中，第二組核酸代表至少20種不同基因座或基因，較佳至少40種不同基因座或基因，且更佳至少100、至少500、至少1000或至少5000種不同基因座或基因，諸如100至10,000種不同基因座或基因中之染色體相互作用。第二組核酸之長度適合於其根據Watson Crick鹼基配對與第一組核酸特異性地雜交，以允許鑑別對子群組具有特異性之染色體相互作用。通常地，第二組核酸將包含在序列中對應於以染色體相互作用聚集在一起的兩個染色體區域的兩個部分。第二組核酸通常包含長度為至少10、較佳20且仍較佳30個鹼基(核苷酸)的核酸序列。在另一態樣中，核酸序列之長度可為至多500、較佳至多100且仍較佳至多50個鹼基對。在一較佳態樣中，第二組核酸包含具有17與25個鹼基對之間的核酸序列。在一個態樣中，至少100%、80%或50%之第二組核酸序列具有如上文所描述之長度。較佳地，不同核酸不具有任何重疊序列，例如至少100%、90%、80%或50%之核酸在至少5個連續核苷酸上不具有相同序列。
鑒於第二組核酸充當『索引』，則相同組的第二核酸可與代表不同特徵之子群組的不同組的第一核酸一起使用，亦即第二組核酸可代表可用於鑑別與不同特徵相關之染色體相互作用的核酸之『統一』集合。
第一組核酸 第一組核酸通常來自與預後相關之子群組。第一核酸可具有本文中提及之第二組核酸之特徵及特性中之任一者。第一組核酸通常來源於來自如本文中所描述進行治療及處理，特定言之EpiSwitchTM 交聯及裂解步驟之個體的樣品。通常，第一組核酸代表所有或至少80%或50%的存在於獲自個體之樣品中之染色體相互作用。
通常，與由第二組核酸代表之染色體相互作用相比，第一組核酸代表由第二組核酸代表之基因座或基因中更小群體的染色體相互作用，亦即第二組核酸代表一組限定基因座或基因中之一組背景或索引相互作用。
核酸庫 本文中提及的核酸群體之類型中之任一者可以包含至少200、至少500、至少1000、至少5000或至少10000種該類型之不同核酸(諸如『第一』或『第二』核酸)的庫形式存在。此庫可呈結合於陣列之形式。庫可包含表1、表2、表3或表4中之任一者所示的探針或引子對中之一些或全部。庫可呈組合物之形式或可呈其中核酸提供於單獨容器中之套組之形式。
雜交 本發明需要一種用於允許來自第一組核酸及第二組核酸之互補核酸序列全部地或部分地進行雜交之方式。在一個態樣中，使所有第一組核酸在單一分析中，亦即在單一雜交步驟中與所有第二組核酸接觸。然而，可使用任何適合的分析。
經標記核酸及雜交 圖案 本文中提及之核酸可較佳使用諸如螢光團(螢光分子)之單獨標記物或幫助偵測成功的雜交的放射性標記物進行標記。可在UV光下偵測到某些標記物。例如在本文描述之陣列上的雜交圖案代表兩個子群組之間的表觀遺傳染色體相互作用中之差異，且因此提供一種比較表觀遺傳染色體相互作用且判定哪些表觀遺傳染色體相互作用對本發明之群體中之子群組具有特異性的方法。
術語『雜交圖案』廣泛地涵蓋第一組核酸與第二組核酸之間存在或不存在雜交，亦即哪些來自第一組之特定核酸與哪些來自第二組之特定核酸雜交，且因此其不限於任何特定分析或技術，或需要具有其上可偵測到『圖案』的表面或陣列。
選擇具有特定特徵之子群組 本發明提供一種包含偵測存在或不存在染色體相互作用，通常5至20或5至500種此類相互作用，較佳20至300或50至100種相互作用，以便判定存在或不存在與個體之預後相關之特徵的方法。較佳地，染色體相互作用為本文中提及之基因中之任一者中的彼等染色體相互作用。在一個態樣中，經分類之染色體相互作用為表1、表2、表3或表4中之核酸所代表的彼等染色體相互作用。表中名稱為『偵測到環』的行展示哪些子群組係藉由各探針來偵測。可在該子群組中偵測存在或不存在染色體相互作用。
所測試之個體 所測試之個體通常為本文中提及之任何物種。另外，可以一些方式選擇在本發明之方法中測試之個體。個體可能易患本文中提及之任何病況及/或可能需要提及之任何療法。個體可接受本文中提及之任何療法。特定言之，個體可能患有ASD或疑似患有ASD。
個體可疑似患有在廣泛定義之ASD內出現的任何特定病況。該病況可為自閉症、兒童自閉症、亞斯伯格症候群、PDD-NOS (廣泛性發展障礙)、兒童崩解症、成癮(例如，對物質或數位媒體裝置成癮)。
對標記之組合進行分類 本發明包括一種其中對染色體相互作用之特定組合進行分類的方法： (i)     包含所有由表1、表2、表3或表4中之探針所代表的染色體相互作用；及/或 (ii)    包含至少25、50、100、150或200種由表1、表2、表3或表4中之探針所代表的染色體相互作用；及/或 (iii)   其一起存在於至少10、20、30或40種列於表1、表2、表3或表4中的區域或基因中；及/或 (iv)   其中至少10、20、30或40種經分類之染色體相互作用存在於包含或側接由表1、表2、表3或表4中之探針所代表之染色體相互作用的4,000個鹼基區域中。
通常，本發明之方法中，至少20、30、40或50種染色體相互作用係經分類。
較佳的基因區域、基因座、基因及染色體相互作用 以本發明之所有態樣而言，較佳的基因區域、基因座、基因及染色體相互作用在表中提及，例如在表1、表2、表3或表4。通常，在本發明之方法中，表1中所列至少10、20、30、40或50個之基因係偵測到染色體相互作用。通常，在本發明之方法中，表2中所列至少10、20、30、40或50個之基因係偵測到染色體相互作用。通常，在本發明之方法中，表3中所列至少10、20、30、40或50個之基因係偵測到染色體相互作用。通常，在本發明之方法中，表4中所列至少10、20、30、40或50個之基因係偵測到染色體相互作用。
較佳地，偵測存在或不存在至少10、20、50、150或200種由表1中之探針序列所代表的相關特定染色體相互作用。較佳地，偵測存在或不存在至少10、20、50、150或200種由表2中之探針序列所代表的相關特定染色體相互作用。較佳地，偵測存在或不存在至少10、20、50、150或200種由表3中之探針序列所代表的相關特定染色體相互作用。較佳地，偵測存在或不存在至少10、20、50、150或200種由表4中之探針序列所代表的相關特定染色體相互作用。染色體相互作用可在本文中提及之基因中之任一者的上游或下游，例如在例如距編碼序列之上游50 kb或下游20 kb內。
較佳的標記組合及數目 在一個態樣中，本發明係關於表1中所代表之分類標記。在此態樣中，經分類之標記可存在於任何其他表中或可不存在於任何其他表中。因此，本發明包括一種用於藉由對表1中所代表之染色體相互作用中之一或多者進行分類來判定ASD之預後的方法。通常，偵測存在或不存在至少1、5、8、10、15、20種來自表1之染色體相互作用。
在一個態樣中，本發明係關於表2中所代表之分類標記。在此態樣中，經分類之標記可存在於任何其他表中或可不存在於任何其他表中。因此，本發明包括一種用於藉由對表2中所代表之染色體相互作用中之一或多者進行分類來判定ASD之預後的方法。通常，偵測存在或不存在至少1、5、8、10、15、20種來自表2之染色體相互作用。
在一個態樣中，本發明係關於表3中所代表之分類標記。在此態樣中，經分類之標記可存在於任何其他表中或可不存在於任何其他表中。因此，本發明包括一種用於藉由對表3中所代表之染色體相互作用中之一或多者進行分類來判定ASD之預後的方法。通常，偵測存在或不存在至少1、5、8、10、15、20種來自表3之染色體相互作用。
在一個態樣中，本發明係關於表4中所代表之分類標記。在此態樣中，經分類之標記可存在於任何其他表中或可不存在於任何其他表中。因此，本發明包括一種用於藉由對表4中所代表之染色體相互作用中之一或多者進行分類來判定ASD之預後的方法。通常，偵測存在或不存在至少1、5、8、10、15、20種來自表4之染色體相互作用。
在一個態樣中，本發明係關於表8中所代表之分類標記。在此態樣中，經分類之標記可存在於任何其他表中或可不存在於任何其他表中。因此，本發明包括一種用於藉由對表8中所代表之染色體相互作用中之一或多者進行分類來判定ASD之預後的方法。通常，偵測存在或不存在至少1、5、8、10、15、20種來自表8之染色體相互作用。在一個態樣中，偵測存在或不存在至少30、50、80、100或150種來自表8之相互作用。
表8含有其中如下定義之標記群組： 群組A：編號1至12之標記 群組B：編號13至76及139至167之標記 群組C：編號77至138之標記 群組D：編號168至183之標記
通常，偵測存在或不存在至少1、5、8、10種或所有來自表8之群組A的染色體相互作用。在一個態樣中，偵測存在或不存在至少1、5、8、10、15、20種或所有來自表8之群組B的染色體相互作用。通常，偵測存在或不存在至少1、5、8、10、15、20種或所有來自表8之群組C的染色體相互作用。在一個態樣中，偵測存在或不存在至少1、5、8、10、15、20種或所有來自表8之群組D的染色體相互作用。
在一個態樣中，本發明係關於表9中所代表之分類標記。在此態樣中，經分類之標記可存在於任何其他表中或可不存在於任何其他表中。因此，本發明包括一種用於藉由對表9中所代表之染色體相互作用中之一或多者進行分類來判定ASD之預後的方法。通常，偵測存在或不存在至少1、5、8、10、15、20種來自表9之染色體相互作用。在一個態樣中，偵測存在或不存在至少30、50、80、100或150種來自表9之相互作用。
表9含有其中如下定義之標記群組： 群組A：編號2至7及9至15之標記 群組B：編號1、8、16至87及149至171之標記 群組C：編號88至148之標記 群組D：編號172至182之標記
通常，偵測存在或不存在至少1、5、8、10種或所有來自表9之群組A的染色體相互作用。在一個態樣中，偵測存在或不存在至少1、5、8、10、15、20種或所有來自表9之群組B的染色體相互作用。通常，偵測存在或不存在至少1、5、8、10、15、20種或所有來自表9之群組C的染色體相互作用。在一個態樣中，偵測存在或不存在至少1、5、8種或所有來自表9之群組D的染色體相互作用。
在一個態樣中，偵測存在或不存在至少1、5、8、10、15、20種或所有來自表10之染色體相互作用。在一較佳態樣中，對表10之前兩個標記中之一或兩者進行分類。
對圖式中提及之染色體相互作用進行分類 在一個態樣中，本發明之方法包含對與圖式中之任一者中提及之任何基因相關的一或多種染色體相互作用進行分類(如表中所定義)。通常，對至少1、5、8、10、15或20種此類相互作用進行分類。
對不同類型之 ASD 進行分類 如將自表中瞭解，不同標記對不同類型之ASD具有特異性(由不同標記存在或不存在限定)。本發明之方法通常包含對具有以下特徵中之任一者的標記進行分類： (i)     存在於健康對照(HC)中，但不存在於輕度及重度ASD中 (ii)    輕度或重度ASD特有，且不存在於HC中 (iii)   常見或存在於重度及輕度ASD中，但不存在於HC中 (iv)   存在或不存在於重度或輕度ASD中。
在一個態樣中，對至少1、5、8、10、15或20種具有特徵(i)之染色體相互作用進行分類。在另一態樣中，對至少1、5、8、10、15或20種具有特徵(ii)之染色體相互作用進行分類。在一個態樣中，對至少1、5、8、10、15或20種具有特徵(iii)之染色體相互作用進行分類。在另一態樣中，對至少1、5、8、10、15或20種具有特徵(vi)之染色體相互作用進行分類。
染色體相互作用之類型 在一個態樣中，基因座(包括其中偵測到染色體相互作用的基因及/或位置)可包含CTCF結合位點。此為能夠結合轉錄抑制物CTCF之任何序列。該序列可由序列CCCTC組成或包含該序列CCCTC，其可在基因座處以1、2或3個複本存在。CTCF結合位點序列可包含序列CCGCGNGGNGGCAG (在IUPAC標記法中)。CTCF結合位點可在染色體相互作用之至少100、500、1000或4000個鹼基內或在表1、表2、表3或表4所示的染色體區域中之任一者內。CTCF結合位點可在染色體相互作用之至少100、500、1000或4000個鹼基內或在表1、表2、表3或表4所示的染色體區域中之任一者內。
在一個態樣中，偵測到之染色體相互作用係存在於表1、表2、表3或表4所示之基因區域中之任一者處。若在方法中偵測到經接合核酸，則可偵測到表1、表2、表3或表4中之探針序列中之任一者中所示的序列。
因此，通常可偵測到來自兩個探針區域(亦即，來自兩個染色體相互作用位點)之序列。在較佳態樣中，在方法中使用包含與任何表中所示之探針相同或互補的序列或由其組成的探針。在一些態樣中，包含與表中所示之探針序列中之任一者同源之序列的探針。
在一個態樣中，經分類之染色體相互作用中之一或多者係在基因座/區域處，該基因座/區域： (i)     包含單核苷酸多形現象(SNP)；及/或 (ii)    表現微RNA (miRNA)；及/或 (iii)   表現非編碼RNA (ncRNA)；及/或 (iv)   表現編碼至少10個連續胺基酸殘基之核酸序列；及/或 (v)    表現調節元件；及/或 (vii)  包含CTCF結合位點。
表之描述 表1展示存在於健康對照，但不存在於重度及輕度自閉症中之標記。名稱『mHC』意謂其不存在於輕度及重度自閉症兩者中(mHC，意謂相比於HC來自輕度自閉症)。名稱『sHC』意謂其不存在於輕度及重度自閉症兩者中(sHC，意謂相比於HC來自重度自閉症)。
表2展示存在於輕度及重度自閉症中之特有標記。名稱『sAD』意謂其不存在於對照及輕度自閉症中。名稱『mAD』意謂其不存在於對照及重度自閉症中。
表3展示存在於重度及輕度自閉症中之共用標記。名稱『sAD』意謂存在於輕度中(意謂相比於HC來自重度自閉症)。名稱『mAD』意謂存在於重度中(意謂相比於HC來自輕度自閉症)。
表4展示不存在於重度或輕度自閉症中之特有標記。名稱『sHC』意謂存在於健康對照中，但僅用於比較重度患者與HC患者。此並不說明關於輕度狀態之任何內容。名稱『mHC』意謂存在於健康對照中，但僅用於比較輕度患者與HC患者。此並不說明關於重度狀態之任何內容。
表8展示與重度自閉症相關的標記。四個標記群組展示於此表中，群組A、B、C及D如上所定義且展示於該表中。標記可選自全部表或選自一群組。
表9展示與輕度自閉症相關的標記。四個標記群組展示於此表中，群組A、B、C及D如上所定義且展示於該表中。標記可選自全部表或選自一群組。
表10展示具有高效能之標記且為最佳組。特定言之，此組包含與NAMPT及MAP2相關的染色體相互作用(該表中之標記編號1及2)。
所有表中之LS行具有『1』或『-1』。此反映如何進行比較，健康對照始終為分子，且因此存在於HC中之顯著標記將為1，且疾病樣品(輕度或重度)始終為分母，且因此存在於疾病樣品中之顯著標記將始終為-1。
該等表展示代表與預後相關之染色體相互作用的探針(EpiswitchTM 標記)資料及基因資料。探針序列展示可用於偵測由在染色體相互作用中聚集在一起的兩個基因區域位點產生之接合產物的序列，亦即探針將包含與經接合產物中之序列互補的序列。第一個兩組起點-終點位置展示探針位置，且第二個兩組起點-終點位置展示相關4kb區域。以下資訊提供於探針資料表中： -   HyperG_Stats：基於超幾何富集之參數在基因座中發現該數量的顯著EpiSwitch™標記之機率的p值 -   Probe Count Total：在基因座處測試的EpiSwitch™構形之總數 -   Probe Count Sig：發現在基因座處統計學上顯著的EpiSwitch™構形之數目 -   FDR HyperG：經多個測試(偽發現率)校正的超幾何p值 -   Percent Sig：相對於在基因座處測試的標記之數目，顯著EpiSwitch™標記之百分比 -   logFC：表觀遺傳比率(FC)之以2為底的對數 -   AveExpr：所有陣列及通道上的探針之平均log2-表現 -   T：適度的t-統計量 -   p-value：原始p值 -   adj. p-value：經調整p值或q值 -    B - B-statistic (lods或B)為差異性表現基因的對數機率。 -   FC-非對數倍數變化 -   FC_1-以約零為中心的非對數倍數變化 -   LS-二進位值，此與FC_1值相關。若FC_1值低於-1.1，將其設定為-1，且若FC_1值高於1.1，則將其設定為1。在彼等值之間，該值為0。
該等表展示其中已發現發生相關染色體相互作用的基因。基因座表中之p值與HyperG Stats相同(基於超幾何富集之參數在基因座中發現該數量的顯著EpiSwitch™標記之機率的p值)。LS行展示存在或不存在與特定子群組相關之相互作用(預後狀態)。
探針經設計遠離Taq1位點30bp。在PCR之情況下，PCR引子通常經設計以偵測經接合產物，但其距Taq1位點之位置會變化。
探針位置： 起點1-片段1上TaqI位點上游之30個鹼基 終點1-片段1上之TaqI限制位點 起點2-片段2上之TaqI限制位點 終點2-片段2上TaqI位點下游之30個鹼基
4kb序列位置： 起點1-片段1上TaqI位點上游之4000個鹼基 終點1-片段1上之TaqI限制位點 起點2-片段2上之TaqI限制位點 終點2-片段2上TaqI位點下游之4000個鹼基
GLMNET值與用於擬合整個最小絕對緊縮與選擇算子(lasso)或彈性網絡(elastic-net)正則化的程序相關(Lambda設置為0.5(彈性網絡))。
某些標記在與共用標記相關的位置處展示兩次，一次在輕度自閉症中提及存在/不存在且一次在重度自閉症中提及存在/不存在。
用於樣品製備及染色體相互作用偵測之較佳態樣 本文描述製備樣品且偵測染色體構形之方法。可使用此等方法之最佳(非習知)型式，例如，如此章節中所描述。
通常，樣品將含有至少2 × 105 個細胞。樣品可含有至多5 × 105 個細胞。在一個態樣中，樣品將含有2 × 105 至5.5 × 105 個細胞。
本文中描述存在於染色體基因座處的表觀遺傳染色體相互作用之交聯。此可能在細胞裂解發生之前進行。細胞裂解可進行3至7分鐘，諸如4至6或約5分鐘。在一些態樣中，細胞裂解進行至少5分鐘及少於10分鐘。
本文中描述了用限制酶消化DNA。通常，使DNA限制在約55℃至約70℃，諸如約65℃下進行約10至30分鐘，諸如約20分鐘之時段。
較佳地，使用產生平均片段大小至多為4000個鹼基對的經接合DNA片段的頻繁切割限制酶。視情況，限制酶產生平均片段大小為約200至300個鹼基對，諸如約256個鹼基對的經接合DNA片段。在一個態樣中，典型片段大小為200個鹼基對至4,000個鹼基對，諸如400至2,000或500至1,000個鹼基對。
在EpiSwitch方法之一個態樣中，不在DNA限制消化步驟與DNA接合步驟之間執行DNA沈澱步驟。
本文中描述了DNA接合。通常，使DNA接合進行5至30分鐘，諸如約10分鐘。
樣品中之蛋白質可以酶方式，例如使用蛋白酶，視情況蛋白酶K消化。蛋白質可以酶方式消化約30分鐘至1小時，例如約45分鐘之時段。在一個態樣中，在消化蛋白質(例如，蛋白酶K消化)之後，不存在交聯逆轉或酚DNA提取步驟。
在一個態樣中，PCR偵測能夠偵測經接合核酸之單一複本，較佳地具有針對存在/不存在經接合核酸之二進位讀數。
圖10展示偵測染色體相互作用之較佳方法。
本發明之方法及用途 本發明之方法可以不同方式描述。其可描述為一種製造經接合核酸之方法，該方法包含：(i)使在染色體相互作用中聚集在一起的染色體區域活體外交聯；(ii)使該經交聯DNA經歷切割或限制消化裂解；及(iii)接合該經交聯裂解DNA末端以形成經接合核酸，其中經接合核酸之偵測可用於判定基因座處之染色體狀態，且其中較佳地： -  基因座可為表1、表2、表3或表4中提及之基因座、區域或基因中之任一者，及/或 -  其中染色體相互作用可為本文中提及之染色體相互作用中之任一者或對應於表1、表2、表3或表4中揭示之探針中之任一者，及/或 -  其中經接合產物可具有或包含：(i)與表1、表2、表3或表4中揭示之探針序列中之任一者相同或同源的序列；或(ii)與(ii)互補之序列。
本發明之方法可描述為一種用於偵測代表群體中之不同子群組的染色體狀態的方法，其包含判定染色體相互作用存在或不存在於基因體之限定表觀遺傳作用區域內，其中較佳地： -   子群組係由存在或不存在病況或病況之類型限定，及/或 -   染色體狀態可在表1、表2、表3或表4中提及之任何基因座、區域或基因處；及/或 -   染色體相互作用可為表1、表2、表3或表4中提及之彼等中之任一者或對應於該表中揭示之探針中之任一者。
本發明包括偵測表1、表2、表3或表4中提及之任何基因座、基因或區域處的染色體相互作用。本發明包括使用本文中提及之核酸及探針來偵測染色體相互作用，例如使用至少1、5、10、20或50種此類核酸或探針以偵測染色體相互作用。核酸或探針較佳地偵測至少1、5、10、20或50種不同基因座或基因中之染色體相互作用。本發明包括使用列於表1、表2、表3或表4中的引子或引子對中之任一者或使用如本文中所描述之此等引子之變體(包含引子序列或包含引子序列之片段及/或同源物的序列)來偵測染色體相互作用。
當分析染色體相互作用是否發生『於』限定基因、區域或位置『內』時，在相互作用中在一起的兩個染色體部分係在限定基因、區域或位置內，或在一些態樣中僅一個染色體部分係在限定基因、區域或位置內。
該等表中所示之標記為『傳播』標記，其存在或不存在與如本文所定義之特定ASD狀態相關(如相關表中所示)。因此，參照其中標記與ASD狀態相關之方式來分析本發明方法之結果。
使用本發明方法來鑑別新治療 對染色體相互作用之瞭解可用於鑑別用於ASD之新治療。本發明提供本文中所定義之染色體相互作用鑑別或設計例如與ASD之療法相關的新治療劑之方法及用途。
同源物 本文中提及聚核苷酸/核酸(例如，DNA)序列之同源物。此類同源物通常例如在至少10、15、20、30、100種或更多種連續核苷酸之區域上或在來自參與染色體相互作用之染色體區域的核酸部分上具有至少70%同源性，較佳至少80%、至少85%、至少90%、至少95%、至少97%、至少98%或至少99%同源性。可基於核苷酸一致性(有時稱為「硬同源性」)來計算同源性。
因此，在一特定態樣中，本文中參照序列一致性百分比提及聚核苷酸/核酸(例如，DNA)序列之同源物。通常，此類同源物例如在至少10、15、20、30、100種或更多種連續核苷酸之區域上或在來自參與染色體相互作用之染色體區域的核酸部分上具有至少70%序列一致性，較佳至少80%、至少85%、至少90%、至少95%、至少97%、至少98%或至少99%序列一致性。
舉例而言，UWGCG封裝提供可用於計算同源性及/或序列一致性%的BESTFIT程式(例如，按其預設設置使用) (Devereux等人(1984) Nucleic Acids Research 12, 第387-395頁)。PILEUP及BLAST演算法可用於計算同源性及/或序列一致性%及/或對齊序列(諸如鑑別等效或對應序列(通常按其預設設置))，例如，如Altschul S. F. (1993) J MoI Evol 36:290-300; Altschul, S, F等人 (1990) J MoI Biol 215:403-10中所描述。
執行BLAST分析之軟體可經由國家生物技術資訊中心(National Center for Biotechnology Information)公開獲得。此演算法涉及藉由鑑別查詢序列中之長度W之短字來首先鑑別得高分序列對(high scoring sequence pair；HSP)，該等短字在與資料庫序列中相同長度之字比對時匹配或滿足某些正值臨限值得分T。T稱作鄰近字得分臨限值(Altschul等人，前述)。此等初始鄰近字命中充當用於啟動搜尋之種子以發現含有其之較長HSP。字命中沿各序列以兩個方向延伸，只要累積比對得分可增加即可。在以下情況時，字命中者沿各方向之延伸中斷：累積比對得分自其達成之最大值降低量X；累積得分由於一或多個負分殘基比對之累加而變成零或低於零；或達至任一序列之末端。BLAST演算法參數W、T及X決定比對之靈敏度及速度。BLAST程式使用以下作為預設：字長度(W)為11，BLOSUM62計分矩陣(參見Henikoff 及Henikoff (1992) Proc. Natl. Acad. Sci. USA 89:10915-10919)比對(B)為50，期望值(E)為10，M=5，N=4，及兩股之比較。
BLAST演算法進行兩個序列之間相似性的統計分析；參見例如Karlin及Altschul (1993) Proc. Natl. Acad. Sci. USA 90: 5873-5787。一種由BLAST演算法提供之相似性量度為最小總機率(P(N))，其提供兩個聚核苷酸序列之間將偶然存在匹配之機率的指示。舉例而言，若第一序列與第二序列之比較中的最小和概率小於約1，較佳小於約0.1，更佳小於約0.01且最佳小於約0.001，則認為序列與另一序列相似。
同源序列通常不同之處在於1、2、3、4個或更多個鹼基，諸如少於10、15或20個鹼基(其可為核苷酸之取代、缺失或插入)。可在上文關於計算同源性及/或序列一致性%提及之區域中之任一者上量測此等變化。
可例如藉由將兩個序列視為單一序列(如同兩個序列接合在一起)以便接著與同樣被視為單一序列之另一引子對進行比較來計算『引子對』之同源性。
陣列 第二組核酸可結合於陣列，且在一個態樣中，存在至少15,000、45,000、100,000或250,000種結合於陣列之不同第二核酸，其較佳代表至少300、900、2000或5000個基因座。在一個態樣中，一種、或多種或所有不同第二核酸群體結合於超過一個不同陣列區域，實際上在陣列上重複以允許進行錯誤偵測。陣列可基於Agilent SurePrint G3 Custom CGH微陣列平台。可藉由雙色系統進行第一核酸與陣列之結合的偵測。
治療劑 ( 例如 ， 其係基於分類個體進行選擇或其係基於根據本發明之測試進行選擇 ) 本文中提及治療劑。本發明提供用於預防或治療某些個體之疾病病況的此類試劑，例如藉由本發明之方法鑑別的彼等試劑。此可包含向需要之個體投與治療有效量之試劑。本發明提供試劑在製造用於預防或治療某些個體之病況之藥劑中的用途。
試劑之調配物將視試劑之性質而定。試劑將以含有試劑及醫藥學上可接受之載劑或稀釋劑的醫藥組合物形式提供。適合的載體及稀釋劑包括等滲鹽水溶液，例如磷酸鹽緩衝鹽水。典型的口服劑量組合物包括錠劑、膠囊、液體溶液及液體懸浮液。試劑可經調配以用於非經腸、靜脈內、肌內、皮下、經皮或口服投藥。
可根據各種參數，尤其根據所使用之物質；待治療之個體之重量及病況；投藥路徑；及所需療程來判定試劑之劑量。醫師將能夠判定任何特定試劑的所需投藥路徑及劑量。然而，適合劑量可為0.1至100 mg/kg體重，諸如1至40 mg/kg體重，例如每天服用1至3次。
治療劑可為本文揭示之任何此類試劑，或可靶向本文揭示之任何『目標』，包括本文在任何表(包括表1、表2、表3或表4)中揭示之任何蛋白質或基因。
ASD 療法 本發明中可使用任何抗ASD療法，例如靶向ASD症狀之任何藥物，諸如旨在調節表現。療法可為神經活性藥物、抗驚厥劑、抗抑鬱劑或抗精神病劑。抗精神病藥可為利培酮(risperidone)或阿立哌唑(aripiprazole)。
本文中提及之物質之形式 本文中提及之物質中之任一者(諸如核酸或治療劑)可呈純化或分離形式。其可呈不同於自然界中所發現之形式，例如其可以與自然界中不存在的其他物質之組合存在。核酸(包括本文中所定義之序列之部分)可具有不同於自然界中所發現之彼等的序列，例如在如關於同源性之章節中所描述之序列中具有至少1、2、3、4種或更多種核苷酸變化。核酸可在5'或3'末端處具有異源序列。核酸可在化學上不同於自然界中所發現之彼等，例如其可以一些方式經修飾，但較佳地仍能夠進行Watson-Crick鹼基配對。適當時，核酸將以雙股或單股形式提供。本發明以單股或雙股形式提供本文中提及之所有特定核酸序列，且因此包括與所揭示之任何序列互補的股。
本發明提供一種用於實施本發明之任何方法，包括偵測與預後相關的染色體相互作用的套組。此套組可包括能夠偵測相關染色體相互作用之特異性結合試劑，諸如能夠偵測由本發明之方法生成的經接合核酸的試劑。存在於套組中之較佳試劑包括能夠與經接合核酸或引子對雜交的探針，例如，如本文中所描述，能夠在PCR反應中擴增經接合核酸。
本發明提供一種能夠偵測相關染色體相互作用之裝置。該裝置較佳包含能夠偵測染色體相互作用之任何特異性結合試劑、探針或引子對，諸如本文描述之任何此類試劑、探針或引子對。
偵測方法 在一個態樣中，使用在PCR反應期間活化時可偵測之探針實施與染色體相互作用相關的經接合序列之定量偵測，其中該經接合序列包含來自在表觀遺傳染色體相互作用中聚集在一起的兩個染色體區域的序列，其中該方法包含使接合序列與探針在PCR反應期間接觸，及偵測探針之活化程度，且其中該探針結合接合位點。方法通常允許使用雙重標記之螢光水解探針以MIQE適應方式偵測特定相互作用。
探針通常用具有失活及活化狀態之可偵測標記進行標記，使得其僅在活化時偵測到。活化程度將與存在於PCR反應中之模板(接合產物)之程度相關。可在所有或一些PCR期間，例如對於至少50%或80%之PCR循環實施偵測。
探針可包含共價連接至寡核苷酸之一端的螢光團及連接至核苷酸之另一端的淬滅劑，使得螢光團之螢光係由淬滅劑淬滅。在一個態樣中，螢光團連接至寡核苷酸之5'末端，且淬滅劑共價連接至寡核苷酸之3'末端。可在本發明之方法中使用的螢光團包括FAM、TET、JOE、雅基馬黃(Yakima Yellow)、HEX、花青(Cyanine) 3、ATTO 550、TAMRA、ROX、德克薩斯紅(Texas Red)、花青3.5、LC610、LC 640、ATTO 647N、花青5、花青5.5及ATTO 680。可與適當螢光團一起使用的淬滅劑包括TAM、BHQ1、DAB、Eclip、BHQ2及BBQ650，視情況其中該螢光團係選自HEX、德克薩斯紅及FAM。螢光團及淬滅劑之較佳組合包括FAM與BHQ1及德克薩斯紅與BHQ2。
在 qPCR 分析中使用探針 本發明之水解探針通常用濃度匹配之陰性對照進行溫度梯度最佳化。較佳地，單步PCR反應經最佳化。更佳地，計算標準曲線。使用在經接合序列之接合點上結合的特定探針之優點為可在不使用嵌套式PCR方法之情況下獲得對經接合序列之特異性。本文所描述之方法允許準確及精確定量低複本數目標。目標接合序列可在溫度梯度最佳化之前經純化，例如經凝膠純化。目標接合序列可經定序。較佳地，使用約10 ng、或5至15 ng、或10至20 ng、或10至50 ng、或10至200 ng模板DNA進行PCR反應。正向及反向引子經設計以使得一種引子結合於經接合DNA序列中所代表的一個染色體區域之序列，且其他引子結合於經接合DNA序列中所代表的另一染色體區域，例如藉由與序列互補。
經接合 DNA 目標之選擇 本發明包括選擇用於如本文所定義之PCR方法中的引子及探針，該選擇包含基於其結合且擴增經接合序列之能力選擇引子及基於其所結合之目標序列之特性，特定言之目標序列之曲率選擇探針序列。
探針通常經設計/選擇以結合於跨越限制位點併接限制片段的經接合序列。在本發明之一個態樣中，例如使用本文中提及之特定演算法計算與特定染色體相互作用相關的可能接合序列之預測曲率。曲率可表述為每螺旋轉角之度數，例如螺旋轉角10.5°。選擇經接合序列以進行靶向，其中經接合序列具有每螺旋轉角至少5°，通常每螺旋轉角至少10°、15°或20°，例如每螺旋轉角5°至20°的曲率傾向峰值得分。較佳地，計算至少20、50、100、200或400個鹼基，諸如接合位點之上游及/或下游20至400個鹼基的每螺旋轉角的曲率傾向得分。因此，在一個態樣中，經接合產物中之目標序列具有此等曲率水準中之任一者。亦可基於最低熱力學結構自由能選擇目標序列。
特定態樣 在一個態樣中，僅對染色體內相互作用進行分類/偵測，且沒有對染色體外相互作用(在不同染色體之間)進行分類/偵測。
在特定態樣中，不對某些染色體相互作用進行分類，例如本文中提及之任何特定相互作用(例如，如由本文中提及之任何探針或引子對所定義)。在一些態樣中，不在本文中提及之基因中之任一者中對染色體相互作用進行分類。
在一個態樣中，不對未列於表中之任一者中的標記進行分類，例如僅對列於表10中之標記進行分類。
篩選方法 本發明提供一種判定哪些染色體相互作用與對應於群體之預後子群組的染色體狀態相關的方法，其包含使來自具有不同染色體狀態之子群組之第一組核酸與第二組索引核酸接觸，且允許互補序列雜交，其中第一組核酸及第二組核酸中之核酸代表經接合產物，該經接合產物包含來自在染色體相互作用中聚集在一起的兩個染色體區域的序列，且其中第一組核酸與第二組核酸之間的雜交圖案允許判定哪些染色體相互作用對預後子群組具有特異性。子群組可為本文中所定義之特定子群組中之任一者，例如參照特定病況或療法。
本發明另外提供一種使用本發明之預後/偵測方法來鑑別或設計ASD之治療劑的方法； -  其中較佳地，該方法用於偵測哪些候選試劑能夠引起與ASD相關的染色體狀態的變化； -  其中染色體相互作用由表1、表2、表3或表4中之任何探針代表；；及/或 -  染色體相互作用存在於列於表1、表2、表3或表4中之任何區域或基因中； 且其中視情況： -   已藉由如技術方案1所定義之判定哪些染色體相互作用與染色體狀態相關的方法來鑑別染色體相互作用，及/或 -   使用以下來監測染色體相互作用的變化：(i)與表1、表2、表3或表4中提及之探針序列中之任一者具有至少70%一致性的探針，及/或(ii)利用與表1、表2、表3或表4中之任何引子對具有至少70%一致性的引子對。
對『傳播』標記進行分類 本文中所提供之資料展示標記為能夠針對相關疾病情形區分病例及非病例的『傳播』標記。因此，當實施本發明時，熟習此項技術者將能夠藉由偵測個體所在的子群組的相互作用進行判定。在一個態樣中，呈與相關疾病情形(不存在或存在)相關之形式的至少70%經測試標記之偵測臨限值可用於判定個體是否在相關子群組中。在其他態樣中，可使用至少80%或至少90%之臨限值。
在一個態樣中，分類器可用作偵測方法之部分，例如利用包含與一或多種傳播標記相關之資訊的經訓練演算法，例如，如本文中之表中任一項中所定義。
公開案 本文中提及的所有公開案之內容以引用之方式併入本說明書中且可用於進一步定義與本發明相關的特徵。
用於鑑別標記及標記組之方法 本文描述之本發明係關於與表型密切相關的自身作為調節模態的染色體構形圖譜及3D架構。生物標記之發現係基於經由圖案識別進行之標註及對代表表型中之差異的臨床樣品之代表性群體進行之篩選。吾等在編碼及非編碼部分上且在大範圍的用於鑑別統計學上傳播一致的條件性傳播染色體構形的已知基因之非編碼5'及3'上標註且篩選基因體之顯著部分，其例如錨定在開放閱讀框架之內(固有的)或開放閱讀框架之外的非編碼位點中。
在選擇最佳標記時，吾等受標記導引之統計資料及p值驅動。標籤內的所選擇及驗證染色體構形自身為傳播分層實體，無論用於參考中之基因之表現圖譜如何。可針對相關調節模態進行另外的工作，諸如錨定位點之SNP、基因轉錄圖譜的變化、H3K27ac含量的變化。
吾等正考慮臨床表型差異及其基於基礎生物學及表觀遺傳學對表型之控制，包括(例如)調節網絡之構架進行分層的問題。因此，為輔助分層，吾人捕獲網絡的變化且其較佳經由若干生物標記之標籤，例如經由遵循用於標記減少的機器學習演算法進行，該機器學習演算法包括評估標記之最佳數目以在最少雜訊下對測試群體進行分層。此可以3至20種標記為終點。
針對各組的標記選擇可藉由交叉驗證統計效能來進行(而非例如藉由用於參考名稱的相鄰基因之功能相關性來進行)。
一組標記(帶有相鄰基因之名稱)為在基因體之顯著部分中進行篩選，以無偏差方式分析基因體之顯著部分中超過14,000至60,000個經標註EpiSwitch位點的統計傳播能力的群集選擇之產物。對於分層問題，不應將其視為對已知功能值之基因進行染色體構形之定製捕獲。染色體相互作用之位點總數為120萬，且因此組合之潛在數目為120萬至120萬次冪。吾等遵循的方法仍然允許鑑別相關染色體相互作用。
以本申請案提供之特定標記業已通過選擇，其在統計學上(顯著)與病況相關。此經相關表中之資料所證實。可將各標記看作代表作為在相關病況中體現之網絡失調之部分的生物表觀遺傳之事件。在實際術語中，其意謂當相較於對照時，此等標記在在患者群組中係普遍的。平均而言，作為一實例，個別標記通常存在於80%經測試患者中及10%經測試對照中。
所有標記之簡單添加不代表一些失調之間的網絡相互關係。此為引入標準多變量生物標記分析GLMNET (R封裝)之地方。GLMNET封裝有助於鑑別一些標記之間的相互依賴性，此反映其在達成產生疾病表型之失調中的共同作用。對具有最高GLMNET得分之標記進行建模且接著測試不僅提供鑑別準確地鑑別患者群體的標記之最小數目，且亦鑑別由於對照組中低發病率之背景統計雜訊而在患者之對照組中提供最少偽陽性結果的最小數目。通常，所選標記(諸如3至10種)之群組(組合)提供偵測之靈敏性與特異性兩者之間的最佳平衡，在多變量分析之情形下自病況之所有所選統計顯著標記之個別特性新出現。
本文中之表展示用於陣列分析的陣列探針(60-mer)之參考名稱，其重疊長程相互作用位點之間的接合點、染色體數目及併接之兩個染色體片段之起點及終點。
特定態樣 EpiSwitch™平台技術偵測基因座處正常病況與異常病況之間的調節變化之表觀遺傳調節標籤。EpiSwitch™平台鑑別且監測與亦稱為染色體構形標籤的人類染色體之調節高階結構相關的基因調節之基本表觀遺傳水準。染色體標籤為基因失調級聯中之不同初始步驟。其為針對生物標記平台具有一組特有優點的高階生物標記，該生物標記平台利用晚期表觀遺傳及基因表現生物標記，諸如DNA甲基化及RNA圖譜分析。
EpiSwitch™ 陣列分析 定製EpiSwitch™陣列-篩選平台具有4種密度(15K、45K、100K及250K)的特有染色體構形，各嵌合片段在陣列上重複4次，從而分別產生有效密度60K、180K、400K及100萬。
定製設計之 EpiSwitch™ 陣列 15K EpiSwitch™陣列可篩選用EpiSwitch™生物標記發現技術詢問的包括約300個基因座的全部基因體。將EpiSwitch™陣列建構在Agilent SurePrint G3 Custom CGH微陣列平台上；此技術提供4種密度(60K、180K、400K及100萬)之探針。在各EpiSwitch™探針重複四次呈現時，將每陣列的密度降低至15K、45K、100K及250K，因此允許對可再生性進行統計評估。每基因座詢問的潛在EpiSwitch™標記之平均數目為50；因此可研究的基因座之數目為300、900、2000及5000。
EpiSwitch™ 定製陣列管道 EpiSwitch™陣列為雙色系統，其中在EpiSwitch™庫產生之後，一組樣品在Cy5中標記，且待比較/分析之其他樣品(對照)在Cy3中標記。使用Agilent SureScan掃描器掃描陣列且使用Agilent特徵提取軟體提取所得特徵。接著使用EpiSwitch™陣列處理腳本R處理資料。使用Bioconductor之標準雙色封裝R:Limma *處理陣列。使用normalisedWithinArrays函數Limma *進行陣列之標準化且此針對晶片上Agilent陽性對照及EpiSwitch™陽性對照進行。基於Agilent Flag調用來過濾資料，將Agilent對照探針移除且將技術複製探針平均化，以便使用Limma *對其進行分析。探針係基於探針在所比較的2種情境之間的差異建模且接著藉由使用偽發現率進行校正。＜=-1.1或=＞1.1且通過p＜=0.1 FDR p值的變化係數(CV)＜=30%之探針係用於進一步篩選。為減少探針設置，使用FactorMineR封裝R進行另外多個因數分析。 *應注意：LIMMA為用於評定微陣列實驗中之差異性表現的線性模型及實驗貝氏方法(Linear Models and Empirical Bayes Processes)。Limma為用於分析由微陣列或RNA-Seq產生之基因表現資料的R封裝。
最初基於經調整p值、FC及CV＜30% (任意截止點)參數選擇探針池以用於最終挑選。僅基於前兩個參數(adj. p-value；FC)獲得進一步分析及最終清單。
統計管道 使用EpiSwitch™分析型封裝R處理EpiSwitch™篩選陣列，以便選擇高值EpiSwitch™標記以供轉譯至EpiSwitch™ PCR平台上。
步驟1 基於其經校正p值(偽發現率，FDR)選擇探針，該P值為經修改線性回歸模型之結果。選擇低於p值＜=0.1的探針且接著藉由其表觀遺傳比率(ER)進一步降低，探針ER必須為＜=-1.1或=＞1.1，以便經選擇用於進一步分析。最後的濾波為變化係數(CV)，探針必須低於＜=0.3。
步驟2 基於其ER選擇來自統計清單的前40種標記，以供選擇作為用於PCR轉譯之標記。具有最高負ER負載之前20種標記及具有最高正ER負載之前20種標記形成清單。
步驟3 來自步驟1之所得標記(統計學上顯著之探針)形成使用超幾何富集(HE)進行富集分析的基礎。此分析使得能夠自顯著探針清單減少標記，且與來自步驟2之標記一起形成轉譯至EpiSwitch™ PCR平台上的探針清單。
統計探針係由HE處理以判定哪些基因位置具有統計學上顯著之探針之富集，從而指示哪些基因位置為表觀遺傳差異之中心。
選擇基於校正p值之最顯著富集基因座以用於探針清單產生。選擇p值低於0.3或0.2的基因位置。映射至此等基因位置之統計探針與來自步驟2之標記一起形成用於EpiSwitch™ PCR轉譯之高值標記。
陣列設計及處理 陣列設計 1. 使用SII軟體(當前v3.2)處理基因座以： a. 撤離此等特定基因座處的基因體之序列(上游50kb及下游20kb之基因序列) b. 限定此區域內之序列參與CC的機率 c. 使用特定RE切割序列 d. 判定哪些限制片段有可能在某些定向中相互作用 e. 將不同CC一起相互作用之可能性進行分級 2. 判定陣列大小且因此判定可利用的探針位置之數目(x) 3. 撤離x/4種相互作用。 4. 對於各相互作用，限定至部分1之限制位點30bp及部分2之限制位點30bp的序列。檢查彼等區域是否重複，若重複則排除且在清單上向下進行下一次相互作用。接合兩個30bp以限定探針。 5. 產生x/4探針加經限定對照探針之清單且重複4次以產生待在陣列上產生的清單 6. 將探針清單上傳於Agilent Sure設計網站上以用於定製CGH陣列。 7. 使用探針群組來設計Agilent定製CGH陣列。
陣列處理 1. 使用EpiSwitch™標準操作程序(SOP)處理樣品以用於模板生產。 2. 藉由陣列處理實驗室用乙醇沈澱淨化。 3. 根據Agilent SureTag完整DNA標記套組(用於血液、細胞或組織的基因體DNA分析酶促標記的基於Agilent寡核苷酸陣列之CGH)處理樣品 4. 使用Agilent C掃描器使用Agilent特徵提取軟體進行掃描。
EpiSwitch TM 生物標記標籤證實複雜疾病表型分層中的高穩定性、靈敏性及特異性。此技術利用表觀遺傳學科學中的最新突破，監測且評估染色體構形標籤作為表觀遺傳生物標記之高度資訊性類別。理論環境中採用的當前研究方法需要3至7天來進行細胞材料之生物化學處理以便偵測CCS。彼等程序具有有限的靈敏性及可再生性；且另外在設計階段不具有由EpiSwitch ™分析型封裝提供的針對性見解的益處。
EpiSwitch™ 陣列電腦模擬標記鑑別 藉由EpiSwitch™陣列對來自測試群體的臨床樣品直接評估基因體上之CCS位點，以鑑別所有相關分層導引生物標記。EpiSwitch™陣列平台由於其高通量能力及其快速地篩選大量基因座之能力而用於標記鑑別。所使用之陣列為Agilent定製CGH陣列，其允許詢問經由電腦模擬軟體鑑別之標記。
EpiSwitch™ PCR 接著藉由EpiSwitch ™ PCR或DNA 定序器(亦即Roche 454、Nanopore MinION等)驗證由EpiSwitch ™陣列鑑別之潛在標記。選擇統計學上顯著且顯示最佳可再生性之最前面的PCR標記以用於進一步減少成最終EpiSwitch ™標籤設置，且針對單獨樣品群體進行驗證。可遵循所確定的標準化操作程序方案由經訓練的技術員執行EpiSwitch ™ PCR。所有方案及試劑之製造係在ISO 13485及9001評審下執行，以確保產品質量及轉變方案之能力。EpiSwitch ™PCR 及EpiSwitch ™陣列生物標記平台與對全血及細胞株兩者之分析相容。測試足夠靈敏以使用小體積之血液偵測極低複本數中之異常。
實例 1 鑑別傳播個別染色體構形不僅特定針對泛自閉症障礙 ， 且亦針對輕度自閉症相比於重度自閉症及健康對照的更特定差異 ASD起因之研究因無法基於目標生物標記鑑別自閉群體中之生物學上有意義的子群組而變得複雜，其中當前診斷及照護受精神病學、心理學及兒科學途徑之間的限制、界限及差異影響。當前診斷工具係基於：1)經修訂自閉症診斷訪談(ADI-R)；2)自閉症診斷觀測時間表(ADOS)；兒童自閉症等級量表(CARS)，特定言之用於經由觀測兒童評定嚴重程度。亦使用社交及交際障礙之診斷訪談(DISCO)。大體而言，社交發育缺陷將泛自閉症障礙與其他發育障礙進行區分。
靶向ADS症狀之當前藥物旨在調節社會環境中之行為治療。神經活性藥物、抗驚厥劑、抗抑鬱劑、抗精神病劑。舉例而言，抗精神病劑利培酮及阿立哌唑經FDA批准。此等治療之副作用：體重增加、流口水、攻擊性，通常勝過益處。在不具有與疾病失調之生物亞型有關的目標生物標記的情況下，在個人化醫療之情形下，仍難以針對個別患者選擇有益藥物治療。
吾等使用相對於所彙集健康對照之平均化圖譜，藉由臨床上標註為輕度ASD之12位個別患者及12位患有重度ASD之患者之染色體構形對血液圖譜進行無偏差的完整基因體篩選。
在此等比較中偵測染色體構形不由任何特定基因或對特定基因的任何偏差或關注驅動。針對子群組中之一者鑑別統計學上顯著之染色體構形鑑別了組裝拓樸自主染色體域之調節域，其藉由3D架構之性質影響在範圍內捕獲的基因之調節。其將允許評定生物相關性，將經由EpiSwitch篩選捕獲的基因的所發現無偏差全身性生物標記同與ASD之生物相關性進行比較。實體上，染色體構形長程相互作用之目標位點/錨定點始終在基因體(包括內含子)之非編碼部分內。其並不改變基因體序列(亦即，因其調節性質為非基因的)且因此與任一基因對蛋白質胺基酸組成的任何影響沒有直接關係。
圖1展示存在於輕度或重度ASD (相對於健康對照(HC)進行鑑別)中的前200種統計學上顯著之標記。此兩個標記群組具有重疊，145種標記為統計學上顯著且當相較於HC時存在於重度及輕度ASD兩者中。51種重度ASD標記係重度類型所特有的。55種輕度ASD標記係輕度類型所特有的。
圖2展示針對已確定的顯著標記，在重疊(上游、下游，在域內部重疊)之多個組合情境中鑑別出最近編碼區(基因)作為染色質長程域。與蛋白質編碼區重疊的所有此等組合已經展示具有染色體構形域可如何影響基因之調節的生物實例。
針對在其調節範圍內將潛在地受影響的基因分析輕度ASD所特有的標記(僅存在於輕度ASD中或僅不存在於ASD中的染色體構形)。遍及其蛋白質產物之此等基因接著用於標準Cytoscape網絡建構中，其中相對於蛋白質調節網絡及路徑之已知全身性資料庫檢查蛋白質。結果展示，在輕度ASD失調下藉由染色體構形選擇之基因符合一種緊密的已知調節相互作用網絡及若干關鍵生物學路徑。該清單之頂部為軸突蛋白及神經配蛋白調節之路徑。亦鑑別出Hippo路徑。
已相對於已知轉錄因子結合位點(TFBS)進行特定標記之類似分析。針對重度ADS所特有、輕度ASD所特有及重度及輕度ASD兩者所常見的標記進行此分析。在圖3中在VENN圖示上繪製各群組之顯著富集之TF之數目。舉例而言，對於輕度ASD所特有的標記，特有地富集18種TF，與重度ASD標記之區域中觀測到的富集共用7+5種TF，與常見共用輕度及重度ASD標記富集的TF共用5+5種TF，且針對所有三組ASD標記(輕度、重度、常見時共用)時共用5種TF。鑑別出的經富集TF群組用於標準STRING網絡及路徑富集工具，以經由TF評估哪些調節路徑及網絡受三種標記群組影響。
具有特有輕度AD標記之TF的String網絡經富集以用於控制雌激素信號傳導及Th17分化。圖4展示輕度ASD標記之TF富集路徑。請注意軸突蛋白及神經配蛋白、hippo、成癮路徑。
表5展示相同分析但不僅基於特有地存在於輕度ASD中之染色體構形標記，且亦基於特有地不存在於輕度ASD中之染色體構形標記。標記之特有存在對於偵測測試具有重要的實踐優勢，而標記之特有缺失具有就調節而言有價值的生物見解。針對由輕度及重度ASD兩者與鑑別出之IL4、IL13及Hippo共用的標記進行相同分析。
表6展示與表5相同的分析，但針對輕度及重度ASD兩者的共用(常見) ASD標記。請注意HPV感染路徑。
重度ASD之Cytoscape網絡鑑別IL-4介導之信號傳導路徑。
表7為考慮所有重度ASD特有缺失染色體構形，而非僅特有的存在一種的網絡分析。
圖7為圖3之重複，作為在對重度ASD標記進行String網絡及富集分析之前的提醒。
針對重度ASD標記的TF之String分析及路徑富集鑑別出病毒感染路徑、腦發育及雌激素依賴性GEX。
圖6展示一系列鑑別出的輕度ASD標記路徑以用於進一步分析。圖7展示針對重度ASD的相同標記路徑。
圖8展示基於輕度路徑標記之主分量分析。左邊大橢圓-輕度ASD，左邊小橢圓-重度ASD，右邊橢圓-健康對照。應注意將HC與兩種類型之ASD完全分離，其中相較於輕度ASD，重度ASD以緊密群組驅動(來自輕度ASD標記透視圖的輕度及重度ASD圖譜中之明顯差異)。
圖9展示使用重度ASD路徑標記之相同分析。應注意HC(右邊橢圓)與兩種類型之ASD (左邊橢圓)的較強分離。
分析基因位置GRIN2A，其中如在血液中偵測到重度或輕度ASD特有的顯著EpiSwitchTM 二進位標記，參照H3K27ac的峰位置(峰自身較寬且具有背景雜訊)，如在腦死後活檢體上偵測到。將H3K27ac視為在某些時刻與3D染色體架構之元件相關。回顧性地觀測到，非侵入性二進位標記與兩個時刻之所標示峰位置相關。並非所有H3K27ac峰與輕度ASD患者與重度ASD患者之間的顯著傳播差異相關。
表8至表10提供具有特定效能準則的其他標記之清單及組。對於表10，給出SHAP值，亦即SHapley Additive exPlanations。SHAP值展示各預測因子對目標變量有多少貢獻。
圖11展示輕度ASD所特有之標記的網絡及路徑。
圖12展示在所有輕度ASD標記上形成的網絡之富集。
圖13展示常見ASD標記之路徑富集。
圖14展示在所有常見ASD標記上形成的網絡之富集。
圖15展示重度ASD所特有之標記的網絡路徑。
圖16展示由重度ASD所特有之標記形成的網絡之富集。
圖17展示針對所有重度ASD標記形成的網絡之富集。
圖18展示使用重度ASD標記建構的TF網絡。
圖19展示表10之標記的效能特徵。訓練資料在左側且測試在右側。
結論 EpiSwitch定製Agilent CGH陣列全基因體篩選提供統計學上顯著之標記，其在以下群組之間係顯著的： 1. 存在於健康對照(HC)中，但不存在於輕度及重度ASD中 2. 輕度或重度ASD特有，且不存在於HC中 3. 常見於重度及輕度ASD中，但不存在於HC中 4. 在重度或輕度ASD中不存在的特有現象
在鑑別及患有ASD之患者且對其進行子分類的潛在地令人混淆、主觀及矛盾的方式的情形下，血液中染色體構形水準的無偏差總基因體篩選(作為與ASD相關的全身性非基因失調之量測值)已鑑別統計學上顯著之具有傳播能力的非侵入性生物標記以繼續在健康對照、輕度及重度ASD之間進行區分。對受所鑑別染色體構形控制的基因體區域的分析與牽涉ASD之生物路徑機制、神經失調(軸突蛋白等)、成癮、雌激素、HPV感染及免疫系統重設(NK細胞)一致。免疫反應展示重度ASD子群組中之特定存在。
   探針 基因座
1 ORF1_13_31010097_31011555_31022136_31024228_FF HSPH1; TEX26
2 ORF1_13_31010097_31011555_31022136_31024228_FF HSPH1; TEX26
3 ORF1_2_227779837_227782633_227875567_227878014_FF CCL20; DAW1; rs113776284; rs7556897; rs4973341; rs1811711; rs13384448; rs7591163
4 ORF1_2_227779837_227782633_227875567_227878014_FF CCL20; DAW1; rs113776284; rs7556897; rs4973341; rs1811711; rs13384448; rs7591163
5 ORF1_8_21022651_21025530_21093029_21096890_RR rs7015657; rs500816
6 ORF1_8_21022651_21025530_21093029_21096890_RR rs7015657; rs500816
7 ORF10_11_49143461_49148959_49212875_49219818_FF FOLH1; TRIM64C; rs368939818; rs61886492; rs770894245; rs747052707; rs202680; rs202676
8 ORF10_11_49143461_49148959_49212875_49219818_FF FOLH1; TRIM64C; rs368939818; rs61886492; rs770894245; rs747052707; rs202680; rs202676
9 ORF10_11_75290920_75295115_75323931_75326829_RR ARRB1; rs7952044; rs737410
10 ORF10_11_75290920_75295115_75323931_75326829_RR ARRB1; rs7952044; rs737410
11 ORF10_13_27276527_27282043_27309940_27312084_RR RASL11A; rs9512637
12 ORF10_13_27276527_27282043_27309940_27312084_RR RASL11A; rs9512637
13 ORF10_2_169020149_169021769_169092304_169105070_FF ABCB11; DHRS9; rs886043986; rs2161037
14 ORF10_2_169020149_169021769_169092304_169105070_FF ABCB11; DHRS9; rs886043986; rs2161037
15 ORF10_4_175807779_175809817_175829279_175833051_FR GPM6A; rs13144140
16 ORF10_4_175807779_175809817_175829279_175833051_FR GPM6A; rs13144140
17 ORF10_5_78549630_78552354_78564492_78567388_RF LHFPL2; rs72315235; rs344650
18 ORF10_5_78549630_78552354_78564492_78567388_RF LHFPL2; rs72315235; rs344650
19 ORF10_9_38681931_38686861_38745325_38749296_FF ANKRD18A; CNTNAP3
20 ORF10_9_38681931_38686861_38745325_38749296_FF ANKRD18A; CNTNAP3
21 ORF100_2_209628749_209631690_209659511_209662054_FF MAP2; rs146432517; rs9288410
22 ORF100_2_209628749_209631690_209659511_209662054_FF MAP2; rs146432517; rs9288410
23 ORF101_6_127085111_127088243_127117219_127121367_RR RSPO3; rs1936807; rs4580892; rs719726; rs2745349; rs1936792; rs1936797; rs1936799; rs1936800; rs1555091
24 ORF101_6_127085111_127088243_127117219_127121367_RR RSPO3; rs1936807; rs4580892; rs719726; rs2745349; rs1936792; rs1936797; rs1936799; rs1936800; rs1555091
25 ORF102_3_179882870_179885277_179956050_179960326_FR PEX5L; rs146906651
26 ORF102_3_179882870_179885277_179956050_179960326_FR PEX5L; rs146906651
27 ORF104_6_159103259_159105928_159122150_159125286_RF rs2249937; rs9355260
28 ORF104_6_159103259_159105928_159122150_159125286_RF rs2249937; rs9355260
29 ORF106_1_152738349_152759424_152785124_152809368_RF KPRP; LCE1B; LCE1C; LCE1D; LCE1E; LCE1F; rs7517755; rs77199844; rs6701216
30 ORF106_1_152738349_152759424_152785124_152809368_RF KPRP; LCE1B; LCE1C; LCE1D; LCE1E; LCE1F; rs7517755; rs77199844; rs6701216
31 ORF106_8_74050342_74056528_74077219_74079715_RR LY96; rs6472827
32 ORF106_8_74050342_74056528_74077219_74079715_RR LY96; rs6472827
33 ORF107_18_10063278_10067780_9946347_9948516_RF VAPA; rs8089099; rs29067; rs29066
34 ORF107_18_10063278_10067780_9946347_9948516_RF VAPA; rs8089099; rs29067; rs29066
35 ORF107_6_140794230_140798634_140883673_140900284_RF rs146383502; rs11155133
36 ORF107_6_140794230_140798634_140883673_140900284_RF rs11155133
37 ORF11_12_10066384_10067858_10157054_10158072_FF CLEC1A; CLEC7A; OLR1; rs16910526; rs16910527; rs7309123; rs2078178; rs3901533
38 ORF11_12_10066384_10067858_10157054_10158072_FF CLEC1A; CLEC7A; OLR1; rs16910526; rs16910527; rs7309123; rs2078178; rs3901533
39 ORF11_2_20303337_20304942_20328998_20331608_FR PUM2; rs111612372
40 ORF11_2_20303337_20304942_20328998_20331608_FR PUM2; rs111612372
41 ORF11_2_216695404_216702694_216719705_216724855_FR IGFBP2; IGFBP5
42 ORF11_2_216695404_216702694_216719705_216724855_FR IGFBP2; IGFBP5
43 ORF11_4_152216416_152218364_152265231_152270280_FF FBXW7; rs522743
44 ORF11_4_152216416_152218364_152265231_152270280_FF FBXW7; rs522743
45 ORF11_4_153729106_153731311_153760093_153764783_FF RNF175; SFRP2
46 ORF11_4_153729106_153731311_153760093_153764783_FF RNF175; SFRP2
47 ORF11_4_153729106_153731311_153764783_153769098_FF RNF175; SFRP2
48 ORF11_4_153729106_153731311_153764783_153769098_FF RNF175; SFRP2
49 ORF11_5_6223946_6226870_6298491_6302848_FR rs12518614
50 ORF11_5_6223946_6226870_6298491_6302848_FR rs12518614
51 ORF11_9_38681931_38686861_38758125_38760727_FF ANKRD18A; CNTNAP3
52 ORF11_9_38681931_38686861_38758125_38760727_FF ANKRD18A; CNTNAP3
表1.a1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
1 41; 40 2; 2; 2; 2 0.26460109; 0.271883499; 0.261899069; 0.269983451
2 41; 40 2; 2; 2; 2 0.26460109; 0.271883499; 0.261899069; 0.269983451
3 52; 38 1; 1; 2; 1 0.266738689; 0.244043749; 0.255573168; 0.325888812
4 52; 38 1; 1; 2; 1 0.266738689; 0.244043749; 0.255573168; 0.325888812
5 NA NA NA
6 NA NA NA
7 25; 22 3; 4; 1; 2 0.05677955; 0.016055763; 0.372324987; 0.173304212
8 25; 22 3; 4; 1; 2 0.05677955; 0.016055763; 0.372324987; 0.173304212
9 27 1; 1 0.374553651; 0.37173223
10 27 1; 1 0.374553651; 0.37173223
11 136 1; 1 0.024430673; 0.016981585
12 136 1; 1 0.024430673; 0.016981585
13 28; 49 2; 2; 2; 3 0.204457601; 0.219149094; 0.276096976; 0.190339907
14 28; 49 2; 2; 2; 3 0.204457601; 0.219149094; 0.276096976; 0.190339907
15 68 3; 4 0.224345313; 0.163371308
16 68 3; 4 0.224345313; 0.163371308
17 32 1; 1 0.363856051; 0.35529211
18 32 1; 1 0.363856051; 0.35529211
19 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
20 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
21 60 5; 7 0.05512946; 0.009185497
22 60 5; 7 0.05512946; 0.009185497
23 7 1; 1 0.215038813; 0.227740664
24 7 1; 1 0.215038813; 0.227740664
25 9 1; 1 0.255358235; 0.268692312
26 9 1; 1 0.255358235; 0.268692312
27 NA NA NA
28 NA NA NA
29 5; 14; 14; 14; 14; 12 1; 1; 1; 1; 1; 1; 1; 1; 1; 1; 1; 1 0.166301763; 0.177271291; 0.325643034; 0.337131196; 0.325643034; 0.337131196; 0.325643034; 0.337131196; 0.325643034; 0.337131196; 0.302214299; 0.314913912
30 5; 14; 14; 14; 14; 12 1; 1; 1; 1; 1; 1; 1; 1; 1; 1; 1; 1 0.166301763; 0.177271291; 0.325643034; 0.337131196; 0.325643034; 0.337131196; 0.325643034; 0.337131196; 0.325643034; 0.337131196; 0.302214299; 0.314913912
31 29 2; 2 0.211050406; 0.22548219
32 29 2; 2 0.211050406; 0.22548219
33 111 2; 2 0.12134432; 0.099229264
34 111 2; 2 0.12134432; 0.099229264
35 NA NA NA
36 NA NA NA
37 44; 68; 79 2; 2; 2; 2; 2; 3 0.270943694; 0.275697963; 0.251156755; 0.236353672; 0.219227; 0.224909805
38 44; 68; 79 2; 2; 2; 2; 2; 3 0.270943694; 0.275697963; 0.251156755; 0.236353672; 0.219227; 0.224909805
39 54 5; 6 0.040491239; 0.018151611
40 54 5; 6 0.040491239; 0.018151611
41 27; 73 1; 1; 1; 1 0.374553651; 0.37173223; 0.162201186; 0.138576645
42 27; 73 1; 1; 1; 1 0.374553651; 0.37173223; 0.162201186; 0.138576645
43 143 3; 2 0.107765005; 0.041422991
44 143 3; 2 0.107765005; 0.041422991
45 22; 13 2; 3; 2; 2 0.158567173; 0.050708849; 0.076537269; 0.086128906
46 22; 13 2; 3; 2; 2 0.158567173; 0.050708849; 0.076537269; 0.086128906
47 22; 13 2; 3; 2; 2 0.158567173; 0.050708849; 0.076537269; 0.086128906
48 22; 13 2; 3; 2; 2 0.158567173; 0.050708849; 0.076537269; 0.086128906
49 NA NA NA
50 NA NA NA
51 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
52 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
表1.a2
   FDR_HyperG Percent_Sig logFC AveExpr
1 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.88; 4.88; 5; 5 0.868612787 0.868612787
2 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.88; 4.88; 5; 5 0.598904033 0.598904033
3 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.92; 1.92; 5.26; 2.63 0.62710618 0.62710618
4 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.92; 1.92; 5.26; 2.63 0.530641835 0.530641835
5 NA NA 0.7513734 0.7513734
6 NA NA 0.747960815 0.747960815
7 0.375519541; 0.376115439; 0.375519541; 0.376115439 12; 16; 4.55; 9.09 0.674825025 0.674825025
8 0.375519541; 0.376115439; 0.375519541; 0.376115439 12; 16; 4.55; 9.09 0.65954888 0.65954888
9 0.375519541; 0.376115439 3.7; 3.7 0.602294433 0.602294433
10 0.375519541; 0.376115439 3.7; 3.7 0.595906629 0.595906629
11 0.375519541; 0.376115439 0.74; 0.74 0.555587425 0.555587425
12 0.375519541; 0.376115439 0.74; 0.74 0.550786641 0.550786641
13 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.14; 7.14; 4.08; 6.12 0.938628219 0.938628219
14 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.14; 7.14; 4.08; 6.12 0.755897322 0.755897322
15 0.375519541; 0.376115439 4.41; 5.88 0.650827971 0.650827971
16 0.375519541; 0.376115439 4.41; 5.88 0.561812306 0.561812306
17 0.375519541; 0.376115439 3.12; 3.12 0.7178366 0.7178366
18 0.375519541; 0.376115439 3.12; 3.12 0.664533836 0.664533836
19 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.720345164 0.720345164
20 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.585763865 0.585763865
21 0.375519541; 0.275564898 8.33; 11.67 0.728255496 0.728255496
22 0.375519541; 0.275564898 8.33; 11.67 0.626985795 0.626985795
23 0.375519541; 0.376115439 14.29; 14.29 0.805818181 0.805818181
24 0.375519541; 0.376115439 14.29; 14.29 0.754843188 0.754843188
25 0.375519541; 0.376115439 11.11; 11.11 0.569380297 0.569380297
26 0.375519541; 0.376115439 11.11; 11.11 0.500263031 0.500263031
27 NA NA 0.509897575 0.509897575
28 NA NA 0.50657948 0.50657948
29 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 20; 20; 7.14; 7.14; 7.14; 7.14; 7.14; 7.14; 7.14; 7.14; 8.33; 8.33 0.866207217 0.866207217
30 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 20; 20; 7.14; 7.14; 7.14; 7.14; 7.14; 7.14; 7.14; 7.14; 8.33; 8.33 0.796884387 0.796884387
31 0.375519541; 0.376115439 6.9; 6.9 0.676235261 0.676235261
32 0.375519541; 0.376115439 6.9; 6.9 0.65992899 0.65992899
33 0.375519541; 0.376115439 1.8; 1.8 0.537783958 0.537783958
34 0.375519541; 0.376115439 1.8; 1.8 0.525514832 0.525514832
35 NA NA 0.613602351 0.613602351
36 NA NA 0.577796521 0.577796521
37 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 2.94; 2.94; 2.53; 3.8 0.850834682 0.850834682
38 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 2.94; 2.94; 2.53; 3.8 0.799471663 0.799471663
39 0.375519541; 0.376115439 9.26; 11.11 0.700295531 0.700295531
40 0.375519541; 0.376115439 9.26; 11.11 0.659362838 0.659362838
41 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.7; 3.7; 1.37; 1.37 0.604361909 0.604361909
42 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.7; 3.7; 1.37; 1.37 0.538807176 0.538807176
43 0.375519541; 0.376115439 2.1; 1.4 0.517282981 0.517282981
44 0.375519541; 0.376115439 2.1; 1.4 0.507863493 0.507863493
45 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.09; 13.64; 15.38; 15.38 0.64156671 0.64156671
46 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.09; 13.64; 15.38; 15.38 0.573819811 0.573819811
47 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.09; 13.64; 15.38; 15.38 0.652146396 0.652146396
48 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.09; 13.64; 15.38; 15.38 0.555942825 0.555942825
49 NA NA 0.609340305 0.609340305
50 NA NA 0.59761426 0.59761426
51 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.677345043 0.677345043
52 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.57758614 0.57758614
表1.a3
   t P值 adj.P.Val B FC FC_1 LS
1 15.48213629 0.00000000290 0.00000295 11.76634134 1.825906369 1.825906369 1
2 10.90560599 0.000000141 0.0000121 7.993827062 1.514565565 1.514565565 1
3 14.54112017 0.00000000592 0.00000425 11.09715078 1.544463932 1.544463932 1
4 12.04390392 0.0000000472 0.00000648 9.09410211 1.444571722 1.444571722 1
5 25.72439074 0.00000000000747 0.00000021 17.12798872 1.683394607 1.683394607 1
6 12.9172327 0.0000000225 0.00000846 9.819863175 1.679417371 1.679417371 1
7 12.13583206 0.0000000433 0.00000621 9.17851343 1.596403143 1.596403143 1
8 6.326625846 0.0000389 0.000771167 2.314278452 1.579588621 1.579588621 1
9 11.19275614 0.000000106 0.0000101 8.281365671 1.518129049 1.518129049 1
10 14.86623147 0.00000000460 0.00000374 11.3338263 1.511422107 1.511422107 1
11 9.97024001 0.000000387 0.0000415 7.010942014 1.469766959 1.469766959 1
12 7.304237986 0.0000095 0.000168592 3.689574847 1.464884218 1.464884218 1
13 5.188268027 0.000230155 0.002611351 0.486477599 1.916704881 1.916704881 1
14 7.96757943 0.00000396 0.0000951 4.592800505 1.688681585 1.688681585 1
15 8.406146792 0.00000234 0.000126067 5.19109577 1.570069009 1.570069009 1
16 9.176454561 0.00000091 0.0000378 6.102024196 1.47612235 1.47612235 1
17 10.68763964 0.000000176 0.0000138 7.770816129 1.644713846 1.644713846 1
18 7.604376575 0.0000065 0.000238672 4.149051664 1.585056027 1.585056027 1
19 5.982165578 0.0000653 0.001097327 1.780661324 1.647576169 1.647576169 1
20 6.985570256 0.0000148 0.00022515 3.235258081 1.500833427 1.500833427 1
21 11.11001278 0.000000119 0.0000206 8.182990839 1.656634681 1.656634681 1
22 14.50519177 0.00000000581 0.00000221 11.15480936 1.544335061 1.544335061 1
23 15.37164789 0.000000003 0.00000157 11.79292692 1.748136914 1.748136914 1
24 13.21152003 0.0000000175 0.00000747 10.06384086 1.687448167 1.687448167 1
25 3.215141267 0.007467378 0.029467513 -3.045565381 1.483886037 1.483886037 1
26 2.948006208 0.012206989 0.030334629 -3.634544291 1.414471424 1.414471424 1
27 8.348609612 0.00000251 0.000132277 5.118936878 1.423949097 1.423949097 1
28 9.450440119 0.000000665 0.0000309 6.42147295 1.420677881 1.420677881 1
29 17.02141727 0.000000000928 0.000000911 12.90295478 1.822864364 1.822864364 1
30 10.01427596 0.000000369 0.0000403 7.058479282 1.737345139 1.737345139 1
31 12.30252086 0.0000000372 0.00000569 9.329970688 1.597964392 1.597964392 1
32 14.06352468 0.00000000863 0.00000511 10.73843464 1.580004854 1.580004854 1
33 7.952019371 0.00000404 0.0000963 4.572250314 1.451740867 1.451740867 1
34 7.231237094 0.0000107 0.000330369 3.636164955 1.439447161 1.439447161 1
35 15.15831191 0.00000000369 0.00000351 11.54146845 1.530074979 1.530074979 1
36 18.45463633 0.000000000364 0.000000599 13.76937805 1.492567856 1.492567856 1
37 9.704773837 0.000000517 0.0000497 6.720302935 1.803544078 1.803544078 1
38 11.49090413 0.0000000795 0.00000863 8.572631871 1.740463626 1.740463626 1
39 11.48453583 0.000000083 0.0000165 8.543169301 1.624837601 1.624837601 1
40 11.05061974 0.000000122 0.000011 8.139913014 1.579384939 1.579384939 1
41 10.20129572 0.000000302 0.0000361 7.258274228 1.520306187 1.520306187 1
42 11.03643039 0.000000124 0.0000111 8.12569815 1.452770866 1.452770866 1
43 19.27838714 0.000000000219 0.000000503 14.23104616 1.43125723 1.43125723 1
44 12.12361632 0.0000000456 0.000012 9.1316772 1.42194286 1.42194286 1
45 10.64291847 0.000000191 0.0000275 7.716972128 1.560022363 1.560022363 1
46 9.673151208 0.000000519 0.0000266 6.675396652 1.488459339 1.488459339 1
47 11.98349768 0.0000000519 0.0000129 9.005365404 1.571504492 1.571504492 1
48 8.403692855 0.00000229 0.0000672 5.156809921 1.470129073 1.470129073 1
49 8.55926631 0.00000189 0.0000595 5.352541561 1.525561463 1.525561463 1
50 13.03017616 0.0000000204 0.00000803 9.91419092 1.513212144 1.513212144 1
51 5.77751212 0.0000896 0.001355138 1.455590078 1.599194087 1.599194087 1
52 6.932319235 0.0000159 0.000237022 3.158007229 1.492350217 1.492350217 1
表1.a4
      探針序列 探針位置
偵測到之環 60 mer Chr
1 mHC GAAACAGAATTTCAAAAGGATACTATATTCGATTGATACATGAGTTTTAGTATTTTTTGA 13
2 sHC GAAACAGAATTTCAAAAGGATACTATATTCGATTGATACATGAGTTTTAGTATTTTTTGA 13
3 mHC GCATTGTTTCTTCATTTTATTTTATTTTTCGAAGTCTTCAAGCTGACTACTAAAAATTGG 2
4 sHC GCATTGTTTCTTCATTTTATTTTATTTTTCGAAGTCTTCAAGCTGACTACTAAAAATTGG 2
5 sHC CAGTAATCCTAGAAAGACAACTGATACATCGATTTTCATTTGAAATCTTTCTAATATTCC 8
6 mHC CAGTAATCCTAGAAAGACAACTGATACATCGATTTTCATTTGAAATCTTTCTAATATTCC 8
7 sHC ATTTTTTTTTATTATTATACTTTTAAGTTCGAGCTTTTTGATAAAATTTGAAAAACACAT 11
8 mHC ATTTTTTTTTATTATTATACTTTTAAGTTCGAGCTTTTTGATAAAATTTGAAAAACACAT 11
9 sHC ATAATAAACAAGCAAAATATGTGTACATTCGAGATACTACGAGTTAATAGCATAGGAGAT 11
10 mHC ATAATAAACAAGCAAAATATGTGTACATTCGAGATACTACGAGTTAATAGCATAGGAGAT 11
11 mHC TATTATAATTGACTTATTTTTCCATTATTCGAATACATTTTTCTCTTTGAGTGGGAAGAA 13
12 sHC TATTATAATTGACTTATTTTTCCATTATTCGAATACATTTTTCTCTTTGAGTGGGAAGAA 13
13 mHC TATATTTAATTATAATTGTAACACAATGTCGATATTGAATGACTTCATGTTGTGAAGTTG 2
14 sHC TATATTTAATTATAATTGTAACACAATGTCGATATTGAATGACTTCATGTTGTGAAGTTG 2
15 mHC AATGCTTAAACACCAAGTATATATATTTTCGATATAGTTTAGTTATAACCATAATCATAT 4
16 sHC AATGCTTAAACACCAAGTATATATATTTTCGATATAGTTTAGTTATAACCATAATCATAT 4
17 sHC TTTTCATTTTTTTTTTAAATATGCTATTTCGATTTTCTTTCATCAGGAGTAAGTTTATAG 5
18 mHC TTTTCATTTTTTTTTTAAATATGCTATTTCGATTTTCTTTCATCAGGAGTAAGTTTATAG 5
19 mHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGATGTTACTCTGGAAACAAAGGTCCCCTTG 9
20 sHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGATGTTACTCTGGAAACAAAGGTCCCCTTG 9
21 mHC ATATGAAACCAAATATATAAACTTATTTTCGATTAAGAATTACCGTCTTAAGAAAATCTC 2
22 sHC ATATGAAACCAAATATATAAACTTATTTTCGATTAAGAATTACCGTCTTAAGAAAATCTC 2
23 sHC ATTTTTTTTAGCCCTATCTTCACAGGTATCGACTAAATACTTCTTCAGTAATTACTGAAA 6
24 mHC ATTTTTTTTAGCCCTATCTTCACAGGTATCGACTAAATACTTCTTCAGTAATTACTGAAA 6
25 mHC ATATTACCTTATTTGGAAACAGTTTCATTCGAGTGGCTCAAATGATTATTTTTATAGTTT 3
26 sHC ATATTACCTTATTTGGAAACAGTTTCATTCGAGTGGCTCAAATGATTATTTTTATAGTTT 3
27 mHC ACTTGCTTCTATAAACATTATTGTAAGATCGAGACTCAAAATCATTTGACTCTTCTACAA 6
28 sHC ACTTGCTTCTATAAACATTATTGTAAGATCGAGACTCAAAATCATTTGACTCTTCTACAA 6
29 sHC CTATAGAAATTAAAATAATATTAAGAGTTCGATTATTCTGCTATACTTTTCTCATTATAA 1
30 mHC CTATAGAAATTAAAATAATATTAAGAGTTCGATTATTCTGCTATACTTTTCTCATTATAA 1
31 sHC ACTAAATTTATTTTAACTTTTTTTTTAATCGAGAGTTTTTATAGCACTTACTCTGAGTCT 8
32 mHC ACTAAATTTATTTTAACTTTTTTTTTAATCGAGAGTTTTTATAGCACTTACTCTGAGTCT 8
33 sHC ATGTAAAGAATTTAAAAATAATCAGTTGTCGAGATTATTTTTCAATTTTGGGTGCTCTTC 18
34 mHC ATGTAAAGAATTTAAAAATAATCAGTTGTCGAGATTATTTTTCAATTTTGGGTGCTCTTC 18
35 mHC TACCTTTAACAAAATTCTCTAGACTTTTTCGATTTACATTCTGTTGTTTCATTGCATTAT 6
36 sHC TACCTTTAACAAAATTCTCTAGACTTTTTCGATTTACATTCTGTTGTTTCATTGCATTAT 6
37 mHC ATATTGGTAGAATAATAGTAGATACTATTCGAATGGTATATCCTCATAGTTTTAATCTGT 12
38 sHC ATATTGGTAGAATAATAGTAGATACTATTCGAATGGTATATCCTCATAGTTTTAATCTGT 12
39 mHC TATATGGTACATATTATACATATTTCTATCGATTTTTACAAGAAATTTAAAAATTAGCTT 2
40 sHC TATATGGTACATATTATACATATTTCTATCGATTTTTACAAGAAATTTAAAAATTAGCTT 2
41 mHC ATCCAGATGACCTAAAATATGTTTATTTTCGAAACAATCTCATTTGACAGATGAAGAAAC 2
42 sHC ATCCAGATGACCTAAAATATGTTTATTTTCGAAACAATCTCATTTGACAGATGAAGAAAC 2
43 sHC AACTCTGTATTTTCTTTTGTAAGATTCATCGATCAATAAATCTTTAATCACATTCACAAA 4
44 mHC AACTCTGTATTTTCTTTTGTAAGATTCATCGATCAATAAATCTTTAATCACATTCACAAA 4
45 mHC CATAAATAAACACATGAAATATATGAAATCGAAATTAACCAGAAATCCGAGAACCTGAAA 4
46 sHC CATAAATAAACACATGAAATATATGAAATCGAAATTAACCAGAAATCCGAGAACCTGAAA 4
47 mHC CATAAATAAACACATGAAATATATGAAATCGAAAACTAAATCTCTAATCTCTAACCTTTC 4
48 sHC CATAAATAAACACATGAAATATATGAAATCGAAAACTAAATCTCTAATCTCTAACCTTTC 4
49 sHC TATCTAGATGTAGGTATATATTTATCTATCGATATCTCTGTTTTCTTTTGACTGGTGGTT 5
50 mHC TATCTAGATGTAGGTATATATTTATCTATCGATATCTCTGTTTTCTTTTGACTGGTGGTT 5
51 mHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGAAGTGAAACTGCCTTTGATGGGCTCATCA 9
52 sHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGAAGTGAAACTGCCTTTGATGGGCTCATCA 9
表1.a5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
1 31011524 31011555 31024197 31024228 13 31007554 31011555 31020227 31024228
2 31011524 31011555 31024197 31024228 13 31007554 31011555 31020227 31024228
3 227782602 227782633 227877983 227878014 2 227778632 227782633 227874013 227878014
4 227782602 227782633 227877983 227878014 2 227778632 227782633 227874013 227878014
5 21022651 21022682 21093029 21093060 8 21022651 21026652 21093029 21097030
6 21022651 21022682 21093029 21093060 8 21022651 21026652 21093029 21097030
7 49148928 49148959 49219787 49219818 11 49144958 49148959 49215817 49219818
8 49148928 49148959 49219787 49219818 11 49144958 49148959 49215817 49219818
9 75290920 75290951 75323931 75323962 11 75290920 75294921 75323931 75327932
10 75290920 75290951 75323931 75323962 11 75290920 75294921 75323931 75327932
11 27276527 27276558 27309940 27309971 13 27276527 27280528 27309940 27313941
12 27276527 27276558 27309940 27309971 13 27276527 27280528 27309940 27313941
13 169021738 169021769 169105039 169105070 2 169017768 169021769 169101069 169105070
14 169021738 169021769 169105039 169105070 2 169017768 169021769 169101069 169105070
15 175809786 175809817 175829279 175829310 4 175805816 175809817 175829279 175833280
16 175809786 175809817 175829279 175829310 4 175805816 175809817 175829279 175833280
17 78549630 78549661 78567357 78567388 5 78549630 78553631 78563387 78567388
18 78549630 78549661 78567357 78567388 5 78549630 78553631 78563387 78567388
19 38686830 38686861 38749265 38749296 9 38682860 38686861 38745295 38749296
20 38686830 38686861 38749265 38749296 9 38682860 38686861 38745295 38749296
21 209631659 209631690 209662023 209662054 2 209627689 209631690 209658053 209662054
22 209631659 209631690 209662023 209662054 2 209627689 209631690 209658053 209662054
23 127085111 127085142 127117219 127117250 6 127085111 127089112 127117219 127121220
24 127085111 127085142 127117219 127117250 6 127085111 127089112 127117219 127121220
25 179885246 179885277 179956050 179956081 3 179881276 179885277 179956050 179960051
26 179885246 179885277 179956050 179956081 3 179881276 179885277 179956050 179960051
27 159103259 159103290 159125255 159125286 6 159103259 159107260 159121285 159125286
28 159103259 159103290 159125255 159125286 6 159103259 159107260 159121285 159125286
29 152738349 152738380 152809337 152809368 1 152738349 152742350 152805367 152809368
30 152738349 152738380 152809337 152809368 1 152738349 152742350 152805367 152809368
31 74050342 74050373 74077219 74077250 8 74050342 74054343 74077219 74081220
32 74050342 74050373 74077219 74077250 8 74050342 74054343 74077219 74081220
33 10063278 10063309 9948485 9948516 18 10063278 10067279 9944515 9948516
34 10063278 10063309 9948485 9948516 18 10063278 10067279 9944515 9948516
35 140794230 140794261 140900253 140900284 6 140794230 140798231 140896283 140900284
36 140794230 140794261 140900253 140900284 6 140794230 140798231 140896283 140900284
37 10067827 10067858 10158041 10158072 12 10063857 10067858 10154071 10158072
38 10067827 10067858 10158041 10158072 12 10063857 10067858 10154071 10158072
39 20304911 20304942 20328998 20329029 2 20300941 20304942 20328998 20332999
40 20304911 20304942 20328998 20329029 2 20300941 20304942 20328998 20332999
41 216702663 216702694 216719705 216719736 2 216698693 216702694 216719705 216723706
42 216702663 216702694 216719705 216719736 2 216698693 216702694 216719705 216723706
43 152218333 152218364 152270249 152270280 4 152214363 152218364 152266279 152270280
44 152218333 152218364 152270249 152270280 4 152214363 152218364 152266279 152270280
45 153731280 153731311 153764752 153764783 4 153727310 153731311 153760782 153764783
46 153731280 153731311 153764752 153764783 4 153727310 153731311 153760782 153764783
47 153731280 153731311 153769067 153769098 4 153727310 153731311 153765097 153769098
48 153731280 153731311 153769067 153769098 4 153727310 153731311 153765097 153769098
49 6226839 6226870 6298491 6298522 5 6222869 6226870 6298491 6302492
50 6226839 6226870 6298491 6298522 5 6222869 6226870 6298491 6302492
51 38686830 38686861 38760696 38760727 9 38682860 38686861 38756726 38760727
52 38686830 38686861 38760696 38760727 9 38682860 38686861 38756726 38760727
表1.a6
   探針 PCR- 引子 1_ID PCR_ 引子 1
1 ORF1_13_31010097_31011555_31022136_31024228_FF OBD159_001 CTTCTGGAGTCACTTTCTCTTTTAGA
2 ORF1_13_31010097_31011555_31022136_31024228_FF OBD159_001 CTTCTGGAGTCACTTTCTCTTTTAGA
3 ORF1_2_227779837_227782633_227875567_227878014_FF OBD159_005 CTGAAGTTGTAGCAGGCAGCATCCAT
4 ORF1_2_227779837_227782633_227875567_227878014_FF OBD159_005 CTGAAGTTGTAGCAGGCAGCATCCAT
5 ORF1_8_21022651_21025530_21093029_21096890_RR OBD159_009 GGTGAGGCTTCTGTTTTCGGGAGG
6 ORF1_8_21022651_21025530_21093029_21096890_RR OBD159_009 GGTGAGGCTTCTGTTTTCGGGAGG
7 ORF10_11_49143461_49148959_49212875_49219818_FF OBD159_013 GTTTCAGGACCACCCTCTACACC
8 ORF10_11_49143461_49148959_49212875_49219818_FF OBD159_013 GTTTCAGGACCACCCTCTACACC
9 ORF10_11_75290920_75295115_75323931_75326829_RR OBD159_017 CTGTTCTGGGTGCTTGGGATAGATGC
10 ORF10_11_75290920_75295115_75323931_75326829_RR OBD159_017 CTGTTCTGGGTGCTTGGGATAGATGC
11 ORF10_13_27276527_27282043_27309940_27312084_RR OBD159_021 GTGCCCTTCGCCTAAACACAAGC
12 ORF10_13_27276527_27282043_27309940_27312084_RR OBD159_021 GTGCCCTTCGCCTAAACACAAGC
13 ORF10_2_169020149_169021769_169092304_169105070_FF OBD159_025 CAACCTAACACAACATAGCCTGC
14 ORF10_2_169020149_169021769_169092304_169105070_FF OBD159_025 CAACCTAACACAACATAGCCTGC
15 ORF10_4_175807779_175809817_175829279_175833051_FR OBD159_029 TCTGACTGAACACATATGCT
16 ORF10_4_175807779_175809817_175829279_175833051_FR OBD159_029 TCTGACTGAACACATATGCT
17 ORF10_5_78549630_78552354_78564492_78567388_RF OBD159_033 GTGAAACCACCAGAGTAGTCAGGAAG
18 ORF10_5_78549630_78552354_78564492_78567388_RF OBD159_033 GTGAAACCACCAGAGTAGTCAGGAAG
19 ORF10_9_38681931_38686861_38745325_38749296_FF OBD159_037 GCCAGAAGTTCACAGGCAGGGTG
20 ORF10_9_38681931_38686861_38745325_38749296_FF OBD159_037 GCCAGAAGTTCACAGGCAGGGTG
21 ORF100_2_209628749_209631690_209659511_209662054_FF OBD159_041 CCCTCAGGCTTCTGTTGTTGGCA
22 ORF100_2_209628749_209631690_209659511_209662054_FF OBD159_041 CCCTCAGGCTTCTGTTGTTGGCA
23 ORF101_6_127085111_127088243_127117219_127121367_RR OBD159_045 GTTGCTGCCAGAGACCCATCCCA
24 ORF101_6_127085111_127088243_127117219_127121367_RR OBD159_045 GTTGCTGCCAGAGACCCATCCCA
25 ORF102_3_179882870_179885277_179956050_179960326_FR OBD159_049 GGAGAGTATTATGGATTGAGTGGTCT
26 ORF102_3_179882870_179885277_179956050_179960326_FR OBD159_049 GGAGAGTATTATGGATTGAGTGGTCT
27 ORF104_6_159103259_159105928_159122150_159125286_RF OBD159_053 CCACTTGCCCTGTGCTCGCCAGC
28 ORF104_6_159103259_159105928_159122150_159125286_RF OBD159_053 CCACTTGCCCTGTGCTCGCCAGC
29 ORF106_1_152738349_152759424_152785124_152809368_RF OBD159_057 GACATTTGGTGACCCATTACTCAACA
30 ORF106_1_152738349_152759424_152785124_152809368_RF OBD159_057 GACATTTGGTGACCCATTACTCAACA
31 ORF106_8_74050342_74056528_74077219_74079715_RR OBD159_061 GGCGGGTGGGTATGTGTTATGGG
32 ORF106_8_74050342_74056528_74077219_74079715_RR OBD159_061 GGCGGGTGGGTATGTGTTATGGG
33 ORF107_18_10063278_10067780_9946347_9948516_RF OBD159_065 TTTGGCAAGGCATAGAATAGAATA
34 ORF107_18_10063278_10067780_9946347_9948516_RF OBD159_065 TTTGGCAAGGCATAGAATAGAATA
35 ORF107_6_140794230_140798634_140883673_140900284_RF OBD159_069 GTGTCACAATAAAATGGCATAAAA
36 ORF107_6_140794230_140798634_140883673_140900284_RF OBD159_069 GTGTCACAATAAAATGGCATAAAA
37 ORF11_12_10066384_10067858_10157054_10158072_FF OBD159_073 TCTCTTTCATTGAGTTCTAAGTTA
38 ORF11_12_10066384_10067858_10157054_10158072_FF OBD159_073 TCTCTTTCATTGAGTTCTAAGTTA
39 ORF11_2_20303337_20304942_20328998_20331608_FR OBD159_077 CATTTGTCAACTCACACTCTAAAA
40 ORF11_2_20303337_20304942_20328998_20331608_FR OBD159_077 CATTTGTCAACTCACACTCTAAAA
41 ORF11_2_216695404_216702694_216719705_216724855_FR OBD159_081 GGTGTTACTTGGCTTCTATGCCTTAG
42 ORF11_2_216695404_216702694_216719705_216724855_FR OBD159_081 GGTGTTACTTGGCTTCTATGCCTTAG
43 ORF11_4_152216416_152218364_152265231_152270280_FF OBD159_085 TGAAATGAGCAGGTGGGAGTAGGTGG
44 ORF11_4_152216416_152218364_152265231_152270280_FF OBD159_085 TGAAATGAGCAGGTGGGAGTAGGTGG
45 ORF11_4_153729106_153731311_153760093_153764783_FF OBD159_089 TATGAAATGTAGGAATGCTGTCCCTC
46 ORF11_4_153729106_153731311_153760093_153764783_FF OBD159_089 TATGAAATGTAGGAATGCTGTCCCTC
47 ORF11_4_153729106_153731311_153764783_153769098_FF OBD159_093 TATGAAATGTAGGAATGCTGTCCCTC
48 ORF11_4_153729106_153731311_153764783_153769098_FF OBD159_093 TATGAAATGTAGGAATGCTGTCCCTC
49 ORF11_5_6223946_6226870_6298491_6302848_FR OBD159_097 CTGTTCTCAGCAATGGAATCTCAGGT
50 ORF11_5_6223946_6226870_6298491_6302848_FR OBD159_097 CTGTTCTCAGCAATGGAATCTCAGGT
51 ORF11_9_38681931_38686861_38758125_38760727_FF OBD159_101 CAGAAGTTCACAGGCAGGGTGTCTTG
52 ORF11_9_38681931_38686861_38758125_38760727_FF OBD159_101 CAGAAGTTCACAGGCAGGGTGTCTTG
表1.a7
   PCR- 引子 2_ID PCR_ 引子 2 基因 標記 GLMNET
1 OBD159_003 AGCCTGGGCGACAGAGTGAGACT HSPH1; TEX26 OBD159_001_003 -0.00243741
2 OBD159_003 AGCCTGGGCGACAGAGTGAGACT HSPH1; TEX26 OBD159_001_003 -0.00243741
3 OBD159_007 GAGGTTTTGTCACAGCGAAGCAGTCA CCL20; DAW1; rs113776284; rs7556897; rs4973341; rs1811711; rs13384448; rs7591163 OBD159_005_007 -0.002876667
4 OBD159_007 GAGGTTTTGTCACAGCGAAGCAGTCA CCL20; DAW1; rs113776284; rs7556897; rs4973341; rs1811711; rs13384448; rs7591163 OBD159_005_007 -0.002876667
5 OBD159_011 AGGATTTGGGTCCCTGGTCTCCA rs7015657; rs500816 OBD159_009_011 -0.002158394
6 OBD159_011 AGGATTTGGGTCCCTGGTCTCCA rs7015657; rs500816 OBD159_009_011 -0.002158394
7 OBD159_015 CCAGTTCTTCCCTTCCAGAGCAGG FOLH1; TRIM64C; rs368939818; rs61886492; rs770894245; rs747052707; rs202680; rs202676 OBD159_013_015 -0.000632005
8 OBD159_015 CCAGTTCTTCCCTTCCAGAGCAGG FOLH1; TRIM64C; rs368939818; rs61886492; rs770894245; rs747052707; rs202680; rs202676 OBD159_013_015 -0.000632005
9 OBD159_019 TTTGTGCTTCTTGCTGTGTGTGTGTG ARRB1; rs7952044; rs737410 OBD159_017_019 -0.004167216
10 OBD159_019 TTTGTGCTTCTTGCTGTGTGTGTGTG ARRB1; rs7952044; rs737410 OBD159_017_019 -0.004167216
11 OBD159_023 GAGACTCTGACCCGTCCCCTGAT RASL11A; rs9512637 OBD159_021_023 -0.003093498
12 OBD159_023 GAGACTCTGACCCGTCCCCTGAT RASL11A; rs9512637 OBD159_021_023 -0.003093498
13 OBD159_027 CAAGTGACTCCATTTTGGTTGTGACA ABCB11; DHRS9; rs886043986; rs2161037 OBD159_025_027 -0.002380456
14 OBD159_027 CAAGTGACTCCATTTTGGTTGTGACA ABCB11; DHRS9; rs886043986; rs2161037 OBD159_025_027 -0.002380456
15 OBD159_031 AATACCAACAATAATTTGT GPM6A; rs13144140 OBD159_029_031 -0.000660848
16 OBD159_031 AATACCAACAATAATTTGT GPM6A; rs13144140 OBD159_029_031 -0.000660848
17 OBD159_035 GAAAGTGGTCTTCCTCCGCCTCTAT LHFPL2; rs72315235; rs344650 OBD159_033_035 -0.000406493
18 OBD159_035 GAAAGTGGTCTTCCTCCGCCTCTAT LHFPL2; rs72315235; rs344650 OBD159_033_035 -0.000406493
19 OBD159_039 GCCCAACTCTGCCTGCTGAAATC ANKRD18A; CNTNAP3 OBD159_037_039 -0.002198949
20 OBD159_039 GCCCAACTCTGCCTGCTGAAATC ANKRD18A; CNTNAP3 OBD159_037_039 -0.002198949
21 OBD159_043 GCAGGTATTGCCAGCCACAGCGT MAP2; rs146432517; rs9288410 OBD159_041_043 -0.003078755
22 OBD159_043 GCAGGTATTGCCAGCCACAGCGT MAP2; rs146432517; rs9288410 OBD159_041_043 -0.003078755
23 OBD159_047 CGGTAGCACCAGCCGATGAACTT RSPO3; rs1936807; rs4580892; rs719726; rs2745349; rs1936792; rs1936797; rs1936799; rs1936800; rs1555091 OBD159_045_047 -0.002660313
24 OBD159_047 CGGTAGCACCAGCCGATGAACTT RSPO3; rs1936807; rs4580892; rs719726; rs2745349; rs1936792; rs1936797; rs1936799; rs1936800; rs1555091 OBD159_045_047 -0.002660313
25 OBD159_051 CTCTAAGCCTTGACTTCCCTATCAGC PEX5L; rs146906651 OBD159_049_051 0.000980386
26 OBD159_051 CTCTAAGCCTTGACTTCCCTATCAGC PEX5L; rs146906651 OBD159_049_051 0.000980386
27 OBD159_055 GAGAAAATCTTGAATGGGAATCCAGT rs2249937; rs9355260 OBD159_053_055 -0.004017137
28 OBD159_055 GAGAAAATCTTGAATGGGAATCCAGT rs2249937; rs9355260 OBD159_053_055 -0.004017137
29 OBD159_059 GGAGGCATTTGGCTTGTCCCCAGATT KPRP; LCE1B; LCE1C; LCE1D; LCE1E; LCE1F; rs7517755; rs77199844; rs6701216 OBD159_057_059 -0.001306703
30 OBD159_059 GGAGGCATTTGGCTTGTCCCCAGATT KPRP; LCE1B; LCE1C; LCE1D; LCE1E; LCE1F; rs7517755; rs77199844; rs6701216 OBD159_057_059 -0.001306703
31 OBD159_063 GGTCTTCATTCCTGGTTCCTGGC LY96; rs6472827 OBD159_061_063 -0.003175406
32 OBD159_063 GGTCTTCATTCCTGGTTCCTGGC LY96; rs6472827 OBD159_061_063 -0.003175406
33 OBD159_067 TTTGGCAAGGCATAGAATAGAATA VAPA; rs8089099; rs29067; rs29066 OBD159_065_067 -0.001345057
34 OBD159_067 TTTGGCAAGGCATAGAATAGAATA VAPA; rs8089099; rs29067; rs29066 OBD159_065_067 -0.001345057
35 OBD159_071 CATCCCATTCTCAGCATTTGATTA rs146383502; rs11155133 OBD159_069_071 -0.003773782
36 OBD159_071 CATCCCATTCTCAGCATTTGATTA rs11155133 OBD159_069_071 -0.003773782
37 OBD159_075 TGAGATTGTGCCACTGAACTCCAG CLEC1A; CLEC7A; OLR1; rs16910526; rs16910527; rs7309123; rs2078178; rs3901533 OBD159_073_075 -0.002317351
38 OBD159_075 TGAGATTGTGCCACTGAACTCCAG CLEC1A; CLEC7A; OLR1; rs16910526; rs16910527; rs7309123; rs2078178; rs3901533 OBD159_073_075 -0.002317351
39 OBD159_079 TGGTTTACTGCTGTAGCCTTGACCT PUM2; rs111612372 OBD159_077_079 -0.003104042
40 OBD159_079 TGGTTTACTGCTGTAGCCTTGACCT PUM2; rs111612372 OBD159_077_079 -0.003104042
41 OBD159_083 GCTGCTTAGGGACACCGAAAAGGTTC IGFBP2; IGFBP5 OBD159_081_083 -0.000193892
42 OBD159_083 GCTGCTTAGGGACACCGAAAAGGTTC IGFBP2; IGFBP5 OBD159_081_083 -0.000193892
43 OBD159_087 CGGAAAATGAGGAAGAGAGGAGGATA FBXW7; rs522743 OBD159_085_087 -0.003996906
44 OBD159_087 CGGAAAATGAGGAAGAGAGGAGGATA FBXW7; rs522743 OBD159_085_087 -0.003996906
45 OBD159_091 GGTTCGTGTAACAGCCAGTTCATTTA RNF175; SFRP2 OBD159_089_091 -0.000814697
46 OBD159_091 GGTTCGTGTAACAGCCAGTTCATTTA RNF175; SFRP2 OBD159_089_091 -0.000814697
47 OBD159_095 CCAGGCTACACAGACATAGTTGT RNF175; SFRP2 OBD159_093_095 -0.000471857
48 OBD159_095 CCAGGCTACACAGACATAGTTGT RNF175; SFRP2 OBD159_093_095 -0.000471857
49 OBD159_099 CAATAACTGAATGGCTGAGTCTGAAA rs12518614 OBD159_097_099 -0.004138741
50 OBD159_099 CAATAACTGAATGGCTGAGTCTGAAA rs12518614 OBD159_097_099 -0.004138741
51 OBD159_103 CATTTGGAATCTTCTCACGGTTGCTG ANKRD18A; CNTNAP3 OBD159_101_103 -0.002219289
52 OBD159_103 CATTTGGAATCTTCTCACGGTTGCTG ANKRD18A; CNTNAP3 OBD159_101_103 -0.002219289
表1.a8
   探針 基因座
53 ORF11_9_38681931_38686861_38760727_38762491_FF ANKRD18A; CNTNAP3
54 ORF11_9_38681931_38686861_38760727_38762491_FF ANKRD18A; CNTNAP3
55 ORF11_X_38261316_38264212_38327821_38333719_FR RP5-972B16.2; RPGR; rs5963409; rs771214648; rs606231180; rs606231181; rs137852551; rs267607019; rs730882261; rs398122960; rs527236108; rs869312185; rs1060501181; rs62635004; rs771039023; rs527236109; rs62640593; rs527236112; rs62640590; rs62640589; rs527236111; rs62640587; rs62642057; rs878853374; rs138018739; rs62650220; rs62638651; rs62650218; rs137852550; rs62638646; rs62638644; rs62638643; rs62638637; rs62638636; rs111631988; rs62638634; rs62638630; rs62638629
56 ORF11_X_38261316_38264212_38327821_38333719_FR RP5-972B16.2; RPGR; rs5963409; rs771214648; rs606231180; rs606231181; rs137852551; rs267607019; rs730882261; rs398122960; rs527236108; rs869312185; rs1060501181; rs62635004; rs771039023; rs527236109; rs62640593; rs527236112; rs62640590; rs62640589; rs527236111; rs62640587; rs62642057; rs878853374; rs138018739; rs62650220; rs62638651; rs62650218; rs137852550; rs62638646; rs62638644; rs62638643; rs62638637; rs62638636; rs111631988; rs62638634; rs62638630; rs62638629
57 ORF110_2_21300802_21304831_21382106_21387178_FF rs59014890; rs2337901
58 ORF110_2_21300802_21304831_21382106_21387178_FF rs59014890; rs2337901
59 ORF111_9_28333777_28339631_28367003_28368817_FR LINGO2; rs7851437
60 ORF111_9_28333777_28339631_28367003_28368817_FR LINGO2; rs7851437
61 ORF112_2_21325579_21332004_21387178_21390560_FR rs2337901; rs11897825
62 ORF112_2_21325579_21332004_21387178_21390560_FR rs2337901; rs11897825
63 ORF112_3_127239888_127246012_127301511_127306201_RR C3orf56; rs7610266
64 ORF112_3_127239888_127246012_127301511_127306201_RR C3orf56; rs7610266
65 ORF113_2_21325579_21332004_21387178_21390560_FF rs2337901; rs11897825
66 ORF113_2_21325579_21332004_21387178_21390560_FF rs2337901; rs11897825
67 ORF115_9_105415801_105419712_105449848_105451637_RF FKTN; FSD1L; SLC44A1
68 ORF115_9_105415801_105419712_105449848_105451637_RF FKTN; FSD1L; SLC44A1
69 ORF116_3_37914711_37917540_37993419_37999345_FR CTDSPL; PLCD1; VILL; rs7372209
70 ORF116_3_37914711_37917540_37993419_37999345_FR CTDSPL; PLCD1; VILL; rs7372209
71 ORF117_13_87499323_87503053_87526042_87529747_FF SLITRK5
72 ORF117_13_87499323_87503053_87526042_87529747_FF SLITRK5
73 ORF117_2_209621630_209626755_209659511_209662054_FF MAP2; rs146432517; rs9288410
74 ORF117_2_209621630_209626755_209659511_209662054_FF MAP2; rs146432517; rs9288410
75 ORF119_1_213896516_213907154_213954211_213958027_RF rs7529073; rs4342822
76 ORF119_1_213896516_213907154_213954211_213958027_RF rs7529073; rs4342822
77 ORF119_8_13602479_13607345_13658646_13661358_RR C8orf48
78 ORF119_8_13602479_13607345_13658646_13661358_RR C8orf48
79 ORF12_1_13873315_13874983_13945271_13952984_RF rs7542939
80 ORF12_1_13873315_13874983_13945271_13952984_RF rs7542939
81 ORF12_1_240091688_240094684_240158711_240162261_FR FMN2; rs727502861; rs727502860
82 ORF12_1_240091688_240094684_240158711_240162261_FR FMN2; rs727502861; rs727502860
83 ORF12_1_36409666_36411937_36433268_36434547_RR LSM10; OSCP1
84 ORF12_1_36409666_36411937_36433268_36434547_RR LSM10; OSCP1
85 ORF12_12_75070822_75072825_75136236_75139196_RR CAPS2; KCNC2
86 ORF12_12_75070822_75072825_75136236_75139196_RR CAPS2; KCNC2
87 ORF12_14_50687093_50690663_50737547_50743189_FR NIN; rs387907308; rs146291102
88 ORF12_14_50687093_50690663_50737547_50743189_FR NIN; rs387907308; rs146291102
89 ORF12_2_11479893_11482767_11532162_11535545_RR NIN; rs387907308; rs146291102
90 ORF12_2_11479893_11482767_11532162_11535545_RR E2F6; GREB1; rs77294520
91 ORF12_4_37796365_37802481_37862832_37864637_RR GAFA3; PGM2
92 ORF12_4_37796365_37802481_37862832_37864637_RR GAFA3; PGM2
93 ORF12_9_38681931_38686861_38738766_38743008_FF ANKRD18A; CNTNAP3
94 ORF12_9_38681931_38686861_38738766_38743008_FF ANKRD18A; CNTNAP3
95 ORF12_X_115884702_115886518_115936015_115945579_RF PLS3; rs201386833
96 ORF12_X_115884702_115886518_115936015_115945579_RF PLS3; rs201386833
97 ORF12_X_38261316_38264212_38327821_38333719_FF RP5-972B16.2; RPGR; rs5963409; rs771214648; rs606231180; rs606231181; rs137852551; rs267607019; rs730882261; rs398122960; rs527236108; rs869312185; rs1060501181; rs62635004; rs771039023; rs527236109; rs62640593; rs527236112; rs62640590; rs62640589; rs527236111; rs62640587; rs62642057; rs878853374; rs138018739; rs62650220; rs62638651; rs62650218; rs137852550; rs62638646; rs62638644; rs62638643; rs62638637; rs62638636; rs111631988; rs62638634; rs62638630; rs62638629
98 ORF12_X_38261316_38264212_38327821_38333719_FF RP5-972B16.2; RPGR; rs5963409; rs771214648; rs606231180; rs606231181; rs137852551; rs267607019; rs730882261; rs398122960; rs527236108; rs869312185; rs1060501181; rs62635004; rs771039023; rs527236109; rs62640593; rs527236112; rs62640590; rs62640589; rs527236111; rs62640587; rs62642057; rs878853374; rs138018739; rs62650220; rs62638651; rs62650218; rs137852550; rs62638646; rs62638644; rs62638643; rs62638637; rs62638636; rs111631988; rs62638634; rs62638630; rs62638629
99 ORF123_6_84727932_84732502_84775145_84786636_FF TBX18; rs72912698; rs760905589; rs869320679; rs797045022; rs77693245
100 ORF123_6_84727932_84732502_84775145_84786636_FF TBX18; rs72912698; rs760905589; rs869320679; rs797045022; rs77693245
101 ORF125_21_15444025_15470065_15500094_15503881_RF rs1736020; rs1297265; rs2823286; rs2823288; rs2823310
102 ORF125_21_15444025_15470065_15500094_15503881_RF rs1736020; rs1297265; rs2823286; rs2823288; rs2823310
103 ORF127_5_127434266_127436041_127487600_127490915_RF MEGF10; rs794726677; rs387907071; rs387907072; rs199750143; rs794726678; rs989552169
104 ORF127_5_127434266_127436041_127487600_127490915_RF MEGF10; rs794726677; rs387907071; rs387907072; rs199750143; rs794726678; rs989552169
105 ORF13_1_207936305_207938059_207957832_207960627_RR rs2745959; rs2745967; rs11578508
106 ORF13_1_207936305_207938059_207957832_207960627_RR rs2745959; rs2745967; rs11578508
107 ORF13_11_49143461_49148959_49200052_49204610_FR FOLH1; rs202676; rs368939818; rs61886492; rs770894245; rs747052707; rs202680
108 ORF13_11_49143461_49148959_49200052_49204610_FR FOLH1; rs202676; rs368939818; rs61886492; rs770894245; rs747052707; rs202680
109 ORF13_12_83941063_83942894_83954032_83957600_FF rs11116045; rs1545843
110 ORF13_12_83941063_83942894_83954032_83957600_FF rs11116045; rs1545843
111 ORF13_13_98188349_98189635_98215516_98217335_FR FARP1; RNF113B
112 ORF13_13_98188349_98189635_98215516_98217335_FR FARP1; RNF113B
表1.b1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
53 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
54 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
55 37; 34 2; 2; 2; 2 0.251937703; 0.262259643; 0.239085742; 0.251319324
56 37; 34 2; 2; 2; 2 0.251937703; 0.262259643; 0.239085742; 0.251319324
57 NA NA NA
58 NA NA NA
59 20 6; 4 7.69e-05; 0.007618647
60 20 6; 4 7.69e-05; 0.007618647
61 NA NA NA
62 NA NA NA
63 31 1; 1 0.366789724; 0.359323344
64 31 1; 1 0.366789724; 0.359323344
65 NA NA NA
66 NA NA NA
67 4; 18; 18 1; 1; 2; 2; 2; 2 0.138432982; 0.14804367; 0.123103064; 0.136301816; 0.123103064; 0.136301816
68 4; 18; 18 1; 1; 2; 2; 2; 2 0.138432982; 0.14804367; 0.123103064; 0.136301816; 0.123103064; 0.136301816
69 47; 8; 34 1; 1; 1; 1; 1; 1 0.29419612; 0.273584951; 0.236185646; 0.249326315; 0.357029649; 0.346365974
70 47; 8; 34 1; 1; 1; 1; 1; 1 0.29419612; 0.273584951; 0.236185646; 0.249326315; 0.357029649; 0.346365974
71 6 1; 1 0.191789359; 0.203777963
72 6 1; 1 0.191789359; 0.203777963
73 60 5; 7 0.05512946; 0.009185497
74 60 5; 7 0.05512946; 0.009185497
75 NA NA NA
76 NA NA NA
77 8 2; 1 0.033505489; 0.249326315
78 8 2; 1 0.033505489; 0.249326315
79 NA NA NA
80 NA NA NA
81 52 1; 1 0.266738689; 0.244043749
82 52 1; 1 0.266738689; 0.244043749
83 124; 112 3; 3; 3; 3 0.149414204; 0.126913559; 0.17713842; 0.156487188
84 124; 112 3; 3; 3; 3 0.149414204; 0.126913559; 0.17713842; 0.156487188
85 13; 13 4; 4; 4; 4 0.001148684; 0.001517434; 0.001148684; 0.001517434
86 13; 13 4; 4; 4; 4 0.001148684; 0.001517434; 0.001148684; 0.001517434
87 19 1; 1 0.362286681; 0.369026848
88 19 1; 1 0.362286681; 0.369026848
89 48; 40 4; 1; 4; 1 0.078104352; 0.267628012; 0.050377953; 0.314741981
90 48; 40 4; 1; 4; 1 0.078104352; 0.267628012; 0.050377953; 0.314741981
91 37; 37 5; 8; 5; 8 0.010942367; 0.000107113; 0.010942367; 0.000107113
92 37; 37 5; 8; 5; 8 0.010942367; 0.000107113; 0.010942367; 0.000107113
93 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
94 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
95 29 2; 5 0.211050406; 0.005560973
96 29 2; 5 0.211050406; 0.005560973
97 37; 34 2; 2; 2; 2 0.251937703; 0.262259643; 0.239085742; 0.251319324
98 37; 34 2; 2; 2; 2 0.251937703; 0.262259643; 0.239085742; 0.251319324
99 20 4; 5 0.005899409; 0.001067155
100 20 4; 5 0.005899409; 0.001067155
101 NA NA NA
102 NA NA NA
103 26 3; 3 0.061689421; 0.072111
104 26 3; 3 0.061689421; 0.072111
105 NA NA NA
106 NA NA NA
107 25 3; 4 0.05677955; 0.016055763
108 25 3; 4 0.05677955; 0.016055763
109 NA NA NA
110 NA NA NA
111 22; 19 1; 1; 1; 1 0.372324987; 0.375573766; 0.362286681; 0.369026848
112 22; 19 1; 1; 1; 1 0.372324987; 0.375573766; 0.362286681; 0.369026848
表1.b2
   FDR_HyperG Percent_Sig logFC AveExpr
53 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.821558647 0.821558647
54 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.657823469 0.657823469
55 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.41; 5.41; 5.88; 5.88 0.605549866 0.605549866
56 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.41; 5.41; 5.88; 5.88 0.509980504 0.509980504
57 NA NA 0.829723114 0.829723114
58 NA NA 0.704138453 0.704138453
59 0.008046243; 0.242844385 30; 20 0.572598955 0.572598955
60 0.008046243; 0.242844385 30; 20 0.527267248 0.527267248
61 NA NA 0.79819641 0.79819641
62 NA NA 0.714249608 0.714249608
63 0.375519541; 0.376115439 3.23; 3.23 0.549593463 0.549593463
64 0.375519541; 0.376115439 3.23; 3.23 0.519184321 0.519184321
65 NA NA 0.76945482 0.76945482
66 NA NA 0.637422788 0.637422788
67 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 25; 25; 11.11; 11.11; 11.11; 11.11 0.633540142 0.633540142
68 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 25; 25; 11.11; 11.11; 11.11; 11.11 0.567144081 0.567144081
69 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.13; 2.13; 12.5; 12.5; 2.94; 2.94 0.734451615 0.734451615
70 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.13; 2.13; 12.5; 12.5; 2.94; 2.94 0.541384922 0.541384922
71 0.375519541; 0.376115439 16.67; 16.67 0.565217156 0.565217156
72 0.375519541; 0.376115439 16.67; 16.67 0.553862818 0.553862818
73 0.375519541; 0.275564898 8.33; 11.67 0.778409164 0.778409164
74 0.375519541; 0.275564898 8.33; 11.67 0.551177343 0.551177343
75 NA NA 0.669924722 0.669924722
76 NA NA 0.611561332 0.611561332
77 0.375519541; 0.376115439 25; 12.5 0.752596399 0.752596399
78 0.375519541; 0.376115439 25; 12.5 0.707611524 0.707611524
79 NA NA 0.667711917 0.667711917
80 NA NA 0.583354186 0.583354186
81 0.375519541; 0.376115439 1.92; 1.92 0.54528191 0.54528191
82 0.375519541; 0.376115439 1.92; 1.92 0.536628352 0.536628352
83 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.42; 2.42; 2.68; 2.68 0.604378471 0.604378471
84 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.42; 2.42; 2.68; 2.68 0.584997109 0.584997109
85 0.069549998; 0.082088441; 0.069549998; 0.082088441 30.77; 30.77; 30.77; 30.77 0.577457295 0.577457295
86 0.069549998; 0.082088441; 0.069549998; 0.082088441 30.77; 30.77; 30.77; 30.77 0.529824851 0.529824851
87 0.375519541; 0.376115439 5.26; 5.26 0.569001696 0.569001696
88 0.375519541; 0.376115439 5.26; 5.26 0.502346815 0.502346815
89 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.33; 2.08; 10; 2.5 0.575891896 0.575891896
90 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.33; 2.08; 10; 2.5 0.543154472 0.543154472
91 0.357678624; 0.013656923; 0.357678624; 0.013656923 13.51; 21.62; 13.51; 21.62 0.839780241 0.839780241
92 0.357678624; 0.013656923; 0.357678624; 0.013656923 13.51; 21.62; 13.51; 21.62 0.778361716 0.778361716
93 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.683977936 0.683977936
94 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.589298368 0.589298368
95 0.375519541; 0.217379602 6.9; 17.24 0.548467044 0.548467044
96 0.375519541; 0.217379602 6.9; 17.24 0.495803892 0.495803892
97 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.41; 5.41; 5.88; 5.88 0.760795331 0.760795331
98 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.41; 5.41; 5.88; 5.88 0.635541076 0.635541076
99 0.242080288; 0.077749847 20; 25 1.005383323 1.005383323
100 0.242080288; 0.077749847 20; 25 0.876730419 0.876730419
101 NA NA 0.616499755 0.616499755
102 NA NA 0.49510704 0.49510704
103 0.375519541; 0.376115439 11.54; 11.54 0.716763408 0.716763408
104 0.375519541; 0.376115439 11.54; 11.54 0.599380997 0.599380997
105 NA NA 0.656992374 0.656992374
106 NA NA 0.50757894 0.50757894
107 0.375519541; 0.376115439 12; 16 0.840543337 0.840543337
108 0.375519541; 0.376115439 12; 16 0.786719361 0.786719361
109 NA NA 0.657267171 0.657267171
110 NA NA 0.630565161 0.630565161
111 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 5.26; 5.26 0.635562953 0.635562953
112 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 5.26; 5.26 0.533287999 0.533287999
表1.b3
   t P值 adj.P.Val B FC FC_1 LS
53 5.778191883 0.0000895 0.001353955 1.456679722 1.767314318 1.767314318 1
54 6.892181385 0.0000168 0.000246011 3.099524657 1.57770062 1.57770062 1
55 9.253302738 0.000000833 0.0000357 6.19242406 1.521558567 1.521558567 1
56 11.26586399 0.000000103 0.0000188 8.334293711 1.424030952 1.424030952 1
57 10.28202262 0.000000278 0.0000341 7.34348108 1.777344217 1.777344217 1
58 9.413999651 0.000000693 0.0000319 6.379439954 1.629171467 1.629171467 1
59 10.11175044 0.000000332 0.000038 7.163032837 1.487200288 1.487200288 1
60 11.94636528 0.0000000516 0.00000675 9.003842662 1.441196694 1.441196694 1
61 24.58135563 0.0000000000137 0.000000456 16.37874866 1.738925843 1.738925843 1
62 15.25333763 0.00000000327 0.00000161 11.70817215 1.640629652 1.640629652 1
63 7.860091111 0.00000465 0.000194825 4.490099359 1.463673189 1.463673189 1
64 5.522644599 0.00013213 0.001008571 0.969392732 1.43314474 1.43314474 1
65 18.32758338 0.000000000417 0.00000139 13.52750828 1.704625501 1.704625501 1
66 13.94718949 0.00000000907 0.00000273 10.72148372 1.555547865 1.555547865 1
67 11.52508667 0.0000000798 0.0000163 8.581472574 1.551367132 1.551367132 1
68 10.08307691 0.000000332 0.0000201 7.12980296 1.481587756 1.481587756 1
69 9.299955364 0.000000813 0.0000651 6.263268508 1.663764933 1.663764933 1
70 9.505890351 0.000000625 0.0000298 6.485169411 1.455368935 1.455368935 1
71 5.824949583 0.0000832 0.001291332 1.531472866 1.479610205 1.479610205 1
72 4.959175271 0.000332747 0.001973317 0.016938829 1.46801104 1.46801104 1
73 9.757225935 0.000000488 0.0000478 6.778287569 1.715238465 1.715238465 1
74 10.54534743 0.000000204 0.0000152 7.622959726 1.465280982 1.465280982 1
75 9.815136335 0.000000444 0.0000241 6.834662497 1.59098995 1.59098995 1
76 9.53516435 0.000000623 0.0000554 6.530885843 1.527911871 1.527911871 1
77 17.23990268 0.000000000801 0.000000846 13.04055978 1.684822255 1.684822255 1
78 10.60096551 0.000000199 0.0000282 7.674168825 1.633098177 1.633098177 1
79 12.12630571 0.0000000455 0.000012 9.134087029 1.588551561 1.588551561 1
80 9.576235943 0.000000578 0.0000284 6.5655214 1.498328734 1.498328734 1
81 13.7603685 0.000000011 0.00000579 10.50364376 1.459305472 1.459305472 1
82 7.554087927 0.00000679 0.00013468 4.036394527 1.450578481 1.450578481 1
83 17.27604989 0.000000000782 0.000000844 13.06312691 1.52032364 1.52032364 1
84 20.77446481 0.0000000000975 0.00000086 14.78427402 1.500035983 1.500035983 1
85 9.476856238 0.000000646 0.0000303 6.451857113 1.492216944 1.492216944 1
86 4.701168771 0.000520651 0.00463369 -0.350283943 1.443753907 1.443753907 1
87 7.730294698 0.00000551 0.000216233 4.318032369 1.483496677 1.483496677 1
88 10.01953707 0.000000355 0.0000209 7.060443564 1.416515919 1.416515919 1
89 9.902517743 0.000000416 0.0000434 6.937463666 1.490598689 1.490598689 1
90 15.22110504 0.00000000335 0.00000164 11.68495444 1.457155126 1.457155126 1
91 14.63678274 0.00000000549 0.0000041 11.16741021 1.789777493 1.789777493 1
92 11.54363869 0.0000000755 0.00000841 8.623396595 1.715182054 1.715182054 1
93 6.528038663 0.0000289 0.000636125 2.618471694 1.606563423 1.606563423 1
94 7.982440923 0.00000388 0.0000941 4.612400208 1.504514872 1.504514872 1
95 3.325957648 0.006084037 0.025942826 -2.841364307 1.462530837 1.462530837 1
96 3.959937544 0.001899013 0.007183188 -1.766742449 1.41010627 1.41010627 1
97 13.39746234 0.0000000143 0.00000343 10.27616465 1.694424472 1.694424472 1
98 8.949997713 0.00000122 0.000084 5.854134441 1.553520281 1.553520281 1
99 16.50897497 0.00000000139 0.00000219 12.44435513 2.007476811 2.007476811 1
100 8.460462909 0.00000213 0.0000643 5.228560837 1.836209179 1.836209179 1
101 11.89527738 0.0000000563 0.0000134 8.925067536 1.533150958 1.533150958 1
102 11.69713138 0.0000000653 0.00000768 8.769894288 1.409425322 1.409425322 1
103 12.45056206 0.0000000326 0.00000533 9.462780811 1.643490831 1.643490831 1
104 13.56747572 0.0000000129 0.00000631 10.35127768 1.515066372 1.515066372 1
105 14.74583165 0.00000000505 0.00000398 11.24686929 1.576792013 1.576792013 1
106 9.135658327 0.000000954 0.0000389 6.053777075 1.421662428 1.421662428 1
107 13.74582787 0.0000000112 0.00000579 10.49223964 1.790724424 1.790724424 1
108 14.26887695 0.000000007 0.00000243 10.97352139 1.725147074 1.725147074 1
109 12.63211522 0.0000000277 0.00000492 9.6235096 1.577092381 1.577092381 1
110 6.351029156 0.0000375 0.000753966 2.35144083 1.548171355 1.548171355 1
111 11.79956703 0.0000000592 0.00000729 8.866629894 1.553543839 1.553543839 1
112 6.37193688 0.0000363 0.000737519 2.383212703 1.44722376 1.44722376 1
表1.b4
      探針序列 探針 位置
偵測到之環 60 mer Chr
53 mHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGAAACAGTATTTTCAAAAATAAAATAGACC 9
54 sHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGAAACAGTATTTTCAAAAATAAAATAGACC 9
55 sHC AAAGGAAATATTAAGTATGGAAATACTTTCGACACACAATTATGACACTACTAGTAATAG X
56 mHC AAAGGAAATATTAAGTATGGAAATACTTTCGACACACAATTATGACACTACTAGTAATAG X
57 mHC CAATTCAGATAATAATACTTTTATAATGTCGACAGAGCTACATTAAAAAGGAGAATCTCC 2
58 sHC CAATTCAGATAATAATACTTTTATAATGTCGACAGAGCTACATTAAAAAGGAGAATCTCC 2
59 mHC GCCCACTAAATAGTAATATTAGGATCTATCGATTTCCCACATGGAATATACAGATTTAGC 9
60 sHC GCCCACTAAATAGTAATATTAGGATCTATCGATTTCCCACATGGAATATACAGATTTAGC 9
61 mHC CAAGAAGAAGGGATAAAATACTACTTCTTCGAAAGTGACAATAACCTCCATAATTAAGGG 2
62 sHC CAAGAAGAAGGGATAAAATACTACTTCTTCGAAAGTGACAATAACCTCCATAATTAAGGG 2
63 mHC TTATATGTTTTAAATAACAAAAATTATATCGATCATCTATCTACATGTGTGTATCTCTAT 3
64 sHC TTATATGTTTTAAATAACAAAAATTATATCGATCATCTATCTACATGTGTGTATCTCTAT 3
65 mHC CAAGAAGAAGGGATAAAATACTACTTCTTCGAGATAATTTGAGATTAAATTGACAACATA 2
66 sHC CAAGAAGAAGGGATAAAATACTACTTCTTCGAGATAATTTGAGATTAAATTGACAACATA 2
67 mHC GGAAATAAACAGAGGGATTTTGTTTATATCGATTATCTTACATGTTTCTTAGAATGAATG 9
68 sHC GGAAATAAACAGAGGGATTTTGTTTATATCGATTATCTTACATGTTTCTTAGAATGAATG 9
69 mHC TAGATGAATAAATTTAGACCTTATTAGGTCGAAAAAACTGGAAAAAAAAATTGTCAAGTG 3
70 sHC TAGATGAATAAATTTAGACCTTATTAGGTCGAAAAAACTGGAAAAAAAAATTGTCAAGTG 3
71 mHC CTACTCTTATTCTTCTCTCAAGAAATTATCGATGTTTGAGAAATATACAAATAAAGTAAT 13
72 sHC CTACTCTTATTCTTCTCTCAAGAAATTATCGATGTTTGAGAAATATACAAATAAAGTAAT 13
73 mHC CAATATTATATGTAGAGATTCTTTCATATCGATTAAGAATTACCGTCTTAAGAAAATCTC 2
74 sHC CAATATTATATGTAGAGATTCTTTCATATCGATTAAGAATTACCGTCTTAAGAAAATCTC 2
75 sHC AGCACAAAATAATATAGCATAAAACATATCGACTTATCTGATTTTCACCTCAAATGACCT 1
76 mHC AGCACAAAATAATATAGCATAAAACATATCGACTTATCTGATTTTCACCTCAAATGACCT 1
77 sHC TATTTGTAAATATTTTAGTATTTACAAATCGATTTTCATAATATCCTAAATATGATATAG 8
78 mHC TATTTGTAAATATTTTAGTATTTACAAATCGATTTTCATAATATCCTAAATATGATATAG 8
79 mHC TACATTTTTAGCTCATCATAAAAGATATTCGATTATTTAGAAAAAGAAATGAAGAGATGG 1
80 sHC TACATTTTTAGCTCATCATAAAAGATATTCGATTATTTAGAAAAAGAAATGAAGAGATGG 1
81 mHC ATGAAATAGAGTGTTAGAATTTAATGAATCGAACTGATTAATAATTTTCTTCTGAACCCC 1
82 sHC ATGAAATAGAGTGTTAGAATTTAATGAATCGAACTGATTAATAATTTTCTTCTGAACCCC 1
83 sHC TGGTAAATTGGAGCAGGTGACCTGGGAGTCGAGGCAGCTGCAGGATTTAAATTGGCTGAG 1
84 mHC TGGTAAATTGGAGCAGGTGACCTGGGAGTCGAGGCAGCTGCAGGATTTAAATTGGCTGAG 1
85 sHC TTAACATCTTATTCTAAAAAATAGTTTATCGAAAAATCAGAAATCAGTAACCTAATACTG 12
86 mHC TTAACATCTTATTCTAAAAAATAGTTTATCGAAAAATCAGAAATCAGTAACCTAATACTG 12
87 mHC GGTAATATTTAACTATAGTTCTCAATACTCGAGTGATAAATATTTTGCCAACTTATAAGG 14
88 sHC GGTAATATTTAACTATAGTTCTCAATACTCGAGTGATAAATATTTTGCCAACTTATAAGG 14
89 mHC TTTTCTCAGCTAAGAAAACAAATGAGATTCGAGTCATTAATTCTTGCTTCTTAACTGCTT 2
90 sHC TTTTCTCAGCTAAGAAAACAAATGAGATTCGAGTCATTAATTCTTGCTTCTTAACTGCTT 2
91 mHC AAAGATATAATGTTTCACATATTTTAAATCGATATATTCTACAAACTGCTTTATTGTAGA 4
92 sHC AAAGATATAATGTTTCACATATTTTAAATCGATATATTCTACAAACTGCTTTATTGTAGA 4
93 mHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGACATCCAAGGTCTTCACAATGTGGCTGAC 9
94 sHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGACATCCAAGGTCTTCACAATGTGGCTGAC 9
95 mHC CACACTTGAGCTCATTGTAAACCAAAGCTCGAGAGCGGTCCCGTGGGGGCGGTGTTACTC X
96 sHC CACACTTGAGCTCATTGTAAACCAAAGCTCGAGAGCGGTCCCGTGGGGGCGGTGTTACTC X
97 sHC AAAGGAAATATTAAGTATGGAAATACTTTCGAGAAAGAAACAAATACAGCTAGGAAGCAT X
98 mHC AAAGGAAATATTAAGTATGGAAATACTTTCGAGAAAGAAACAAATACAGCTAGGAAGCAT X
99 mHC AATTATTCAAAAAGACACAATTGTTTTCTCGAACATGTTTTAGTGATTTATATTCACTCA 6
100 sHC AATTATTCAAAAAGACACAATTGTTTTCTCGAACATGTTTTAGTGATTTATATTCACTCA 6
101 mHC AATTCCATATTTTCTAGAAAACAAAAAATCGATTTTAGAAGACTTGAAAAAGTTGTAATT 21
102 sHC AATTCCATATTTTCTAGAAAACAAAAAATCGATTTTAGAAGACTTGAAAAAGTTGTAATT 21
103 sHC AAACTATGTAAAGAAAATTTGAAGAATTTCGATTTTTATTGCCAGAAACGACTCTTAAAG 5
104 mHC AAACTATGTAAAGAAAATTTGAAGAATTTCGATTTTTATTGCCAGAAACGACTCTTAAAG 5
105 mHC CATGTATTTATATTAATATCAAACAAGATCGACCATTATAAAGATTTAACTATTTTATGC 1
106 sHC CATGTATTTATATTAATATCAAACAAGATCGACCATTATAAAGATTTAACTATTTTATGC 1
107 mHC ATTTTTTTTTATTATTATACTTTTAAGTTCGAATCTTTCTAAAACACAGTAAACTCAAAC 11
108 sHC ATTTTTTTTTATTATTATACTTTTAAGTTCGAATCTTTCTAAAACACAGTAAACTCAAAC 11
109 sHC TATGTATTTATATATGATTACCATTATGTCGATGAATCAACATTTTCCAAAATAATACAT 12
110 mHC TATGTATTTATATATGATTACCATTATGTCGATGAATCAACATTTTCCAAAATAATACAT 12
111 sHC CCAATATGTATTCAAATTAAATACGTATTCGACTTTATACTATATGAGAATAAAAAAAGA 13
112 mHC CCAATATGTATTCAAATTAAATACGTATTCGACTTTATACTATATGAGAATAAAAAAAGA 13
表1.b5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
53 38686830 38686861 38762460 38762491 9 38682860 38686861 38758490 38762491
54 38686830 38686861 38762460 38762491 9 38682860 38686861 38758490 38762491
55 38264181 38264212 38327821 38327852 X 38260211 38264212 38327821 38331822
56 38264181 38264212 38327821 38327852 X 38260211 38264212 38327821 38331822
57 21304800 21304831 21387147 21387178 2 21300830 21304831 21383177 21387178
58 21304800 21304831 21387147 21387178 2 21300830 21304831 21383177 21387178
59 28339600 28339631 28367003 28367034 9 28335630 28339631 28367003 28371004
60 28339600 28339631 28367003 28367034 9 28335630 28339631 28367003 28371004
61 21331973 21332004 21387178 21387209 2 21328003 21332004 21387178 21391179
62 21331973 21332004 21387178 21387209 2 21328003 21332004 21387178 21391179
63 127239888 127239919 127301511 127301542 3 127239888 127243889 127301511 127305512
64 127239888 127239919 127301511 127301542 3 127239888 127243889 127301511 127305512
65 21331973 21332004 21390529 21390560 2 21328003 21332004 21386559 21390560
66 21331973 21332004 21390529 21390560 2 21328003 21332004 21386559 21390560
67 105415801 105415832 105451606 105451637 9 105415801 105419802 105447636 105451637
68 105415801 105415832 105451606 105451637 9 105415801 105419802 105447636 105451637
69 37917509 37917540 37993419 37993450 3 37913539 37917540 37993419 37997420
70 37917509 37917540 37993419 37993450 3 37913539 37917540 37993419 37997420
71 87503022 87503053 87529716 87529747 13 87499052 87503053 87525746 87529747
72 87503022 87503053 87529716 87529747 13 87499052 87503053 87525746 87529747
73 209626724 209626755 209662023 209662054 2 209622754 209626755 209658053 209662054
74 209626724 209626755 209662023 209662054 2 209622754 209626755 209658053 209662054
75 213896516 213896547 213957996 213958027 1 213896516 213900517 213954026 213958027
76 213896516 213896547 213957996 213958027 1 213896516 213900517 213954026 213958027
77 13602479 13602510 13658646 13658677 8 13602479 13606480 13658646 13662647
78 13602479 13602510 13658646 13658677 8 13602479 13606480 13658646 13662647
79 13873315 13873346 13952953 13952984 1 13873315 13877316 13948983 13952984
80 13873315 13873346 13952953 13952984 1 13873315 13877316 13948983 13952984
81 240094653 240094684 240158711 240158742 1 240090683 240094684 240158711 240162712
82 240094653 240094684 240158711 240158742 1 240090683 240094684 240158711 240162712
83 36409666 36409697 36433268 36433299 1 36409666 36413667 36433268 36437269
84 36409666 36409697 36433268 36433299 1 36409666 36413667 36433268 36437269
85 75070822 75070853 75136236 75136267 12 75070822 75074823 75136236 75140237
86 75070822 75070853 75136236 75136267 12 75070822 75074823 75136236 75140237
87 50690632 50690663 50737547 50737578 14 50686662 50690663 50737547 50741548
88 50690632 50690663 50737547 50737578 14 50686662 50690663 50737547 50741548
89 11479893 11479924 11532162 11532193 2 11479893 11483894 11532162 11536163
90 11479893 11479924 11532162 11532193 2 11479893 11483894 11532162 11536163
91 37796365 37796396 37862832 37862863 4 37796365 37800366 37862832 37866833
92 37796365 37796396 37862832 37862863 4 37796365 37800366 37862832 37866833
93 38686830 38686861 38742977 38743008 9 38682860 38686861 38739007 38743008
94 38686830 38686861 38742977 38743008 9 38682860 38686861 38739007 38743008
95 115884702 115884733 115945548 115945579 X 115884702 115888703 115941578 115945579
96 115884702 115884733 115945548 115945579 X 115884702 115888703 115941578 115945579
97 38264181 38264212 38333688 38333719 X 38260211 38264212 38329718 38333719
98 38264181 38264212 38333688 38333719 X 38260211 38264212 38329718 38333719
99 84732471 84732502 84786605 84786636 6 84728501 84732502 84782635 84786636
100 84732471 84732502 84786605 84786636 6 84728501 84732502 84782635 84786636
101 15444025 15444056 15503850 15503881 21 15444025 15448026 15499880 15503881
102 15444025 15444056 15503850 15503881 21 15444025 15448026 15499880 15503881
103 127434266 127434297 127490884 127490915 5 127434266 127438267 127486914 127490915
104 127434266 127434297 127490884 127490915 5 127434266 127438267 127486914 127490915
105 207936305 207936336 207957832 207957863 1 207936305 207940306 207957832 207961833
106 207936305 207936336 207957832 207957863 1 207936305 207940306 207957832 207961833
107 49148928 49148959 49200052 49200083 11 49144958 49148959 49200052 49204053
108 49148928 49148959 49200052 49200083 11 49144958 49148959 49200052 49204053
109 83942863 83942894 83957569 83957600 12 83938893 83942894 83953599 83957600
110 83942863 83942894 83957569 83957600 12 83938893 83942894 83953599 83957600
111 98189604 98189635 98215516 98215547 13 98185634 98189635 98215516 98219517
112 98189604 98189635 98215516 98215547 13 98185634 98189635 98215516 98219517
表1.b6
   探針 PCR- 引子 1_ID PCR_ 引子 1
53 ORF11_9_38681931_38686861_38760727_38762491_FF OBD159_105 GCCAGAAGTTCACAGGCAGGGTG
54 ORF11_9_38681931_38686861_38760727_38762491_FF OBD159_105 GCCAGAAGTTCACAGGCAGGGTG
55 ORF11_X_38261316_38264212_38327821_38333719_FR OBD159_109 TTACAGGCGTGAGCCACCAAGCC
56 ORF11_X_38261316_38264212_38327821_38333719_FR OBD159_109 TTACAGGCGTGAGCCACCAAGCC
57 ORF110_2_21300802_21304831_21382106_21387178_FF OBD159_113 ATGGCGAACAGAGTGATGGAGGTGAT
58 ORF110_2_21300802_21304831_21382106_21387178_FF OBD159_113 ATGGCGAACAGAGTGATGGAGGTGAT
59 ORF111_9_28333777_28339631_28367003_28368817_FR OBD159_117 CCAGTAGTATGGTGGCTGTGAATA
60 ORF111_9_28333777_28339631_28367003_28368817_FR OBD159_117 CCAGTAGTATGGTGGCTGTGAATA
61 ORF112_2_21325579_21332004_21387178_21390560_FR OBD159_121 GAGGGAGAGAGACTGAAGGCAGG
62 ORF112_2_21325579_21332004_21387178_21390560_FR OBD159_121 GAGGGAGAGAGACTGAAGGCAGG
63 ORF112_3_127239888_127246012_127301511_127306201_RR OBD159_125 TCACCCTCTGCCTCTGTGTTCTCATC
64 ORF112_3_127239888_127246012_127301511_127306201_RR OBD159_125 TCACCCTCTGCCTCTGTGTTCTCATC
65 ORF113_2_21325579_21332004_21387178_21390560_FF OBD159_129 GGAGAGAGACTGAAGGCAGGAATGCT
66 ORF113_2_21325579_21332004_21387178_21390560_FF OBD159_129 GGAGAGAGACTGAAGGCAGGAATGCT
67 ORF115_9_105415801_105419712_105449848_105451637_RF OBD159_133 GAAAATAACTTGGACTTCAGTGTT
68 ORF115_9_105415801_105419712_105449848_105451637_RF OBD159_133 GAAAATAACTTGGACTTCAGTGTT
69 ORF116_3_37914711_37917540_37993419_37999345_FR OBD159_137 ACTCAGTCCCCTCCCTCAGTAGC
70 ORF116_3_37914711_37917540_37993419_37999345_FR OBD159_137 ACTCAGTCCCCTCCCTCAGTAGC
71 ORF117_13_87499323_87503053_87526042_87529747_FF OBD159_141 ACAGGTAGGTAAACATTTCATAAA
72 ORF117_13_87499323_87503053_87526042_87529747_FF OBD159_141 ACAGGTAGGTAAACATTTCATAAA
73 ORF117_2_209621630_209626755_209659511_209662054_FF OBD159_145 CCATTCTTCCAGAGATGTCAAAACCC
74 ORF117_2_209621630_209626755_209659511_209662054_FF OBD159_145 CCATTCTTCCAGAGATGTCAAAACCC
75 ORF119_1_213896516_213907154_213954211_213958027_RF OBD159_149 GCTCCTGCCATTCAGTTTACCATCTA
76 ORF119_1_213896516_213907154_213954211_213958027_RF OBD159_149 GCTCCTGCCATTCAGTTTACCATCTA
77 ORF119_8_13602479_13607345_13658646_13661358_RR OBD159_153 ATACAGCCACTTCAACTTGTCCTAAT
78 ORF119_8_13602479_13607345_13658646_13661358_RR OBD159_153 ATACAGCCACTTCAACTTGTCCTAAT
79 ORF12_1_13873315_13874983_13945271_13952984_RF OBD159_157 TGCTGTGTGACCTTGGGATGTCC
80 ORF12_1_13873315_13874983_13945271_13952984_RF OBD159_157 TGCTGTGTGACCTTGGGATGTCC
81 ORF12_1_240091688_240094684_240158711_240162261_FR OBD159_161 GGTCAGTGTCAAGCAGTCCAATGAGT
82 ORF12_1_240091688_240094684_240158711_240162261_FR OBD159_161 GGTCAGTGTCAAGCAGTCCAATGAGT
83 ORF12_1_36409666_36411937_36433268_36434547_RR OBD159_165 GAAGCGAGTTGCTGTCACTGGAG
84 ORF12_1_36409666_36411937_36433268_36434547_RR OBD159_165 GAAGCGAGTTGCTGTCACTGGAG
85 ORF12_12_75070822_75072825_75136236_75139196_RR OBD159_169 GGGACACAAATAGACCAAGTAAAT
86 ORF12_12_75070822_75072825_75136236_75139196_RR OBD159_169 GGGACACAAATAGACCAAGTAAAT
87 ORF12_14_50687093_50690663_50737547_50743189_FR OBD159_173 GGTGAAATGGGATGGTGTGCTAT
88 ORF12_14_50687093_50690663_50737547_50743189_FR OBD159_173 GGTGAAATGGGATGGTGTGCTAT
89 ORF12_2_11479893_11482767_11532162_11535545_RR OBD159_177 CATAAACTCCTACCAACTAAGAAT
90 ORF12_2_11479893_11482767_11532162_11535545_RR OBD159_177 CATAAACTCCTACCAACTAAGAAT
91 ORF12_4_37796365_37802481_37862832_37864637_RR OBD159_181 AATAAATAGATACCATCCCAGAGC
92 ORF12_4_37796365_37802481_37862832_37864637_RR OBD159_181 AATAAATAGATACCATCCCAGAGC
93 ORF12_9_38681931_38686861_38738766_38743008_FF OBD159_185 CAGAAGTTCACAGGCAGGGTGTC
94 ORF12_9_38681931_38686861_38738766_38743008_FF OBD159_185 CAGAAGTTCACAGGCAGGGTGTC
95 ORF12_X_115884702_115886518_115936015_115945579_RF OBD159_189 CAGGAATCATTTGACACAATCCCC
96 ORF12_X_115884702_115886518_115936015_115945579_RF OBD159_189 CAGGAATCATTTGACACAATCCCC
97 ORF12_X_38261316_38264212_38327821_38333719_FF OBD159_193 AAACAACTACTATCAGATGAGAAAT
98 ORF12_X_38261316_38264212_38327821_38333719_FF OBD159_193 AAACAACTACTATCAGATGAGAAAT
99 ORF123_6_84727932_84732502_84775145_84786636_FF OBD159_197 GGATGTGTGTGTTGATTCAGCCTTGT
100 ORF123_6_84727932_84732502_84775145_84786636_FF OBD159_197 GGATGTGTGTGTTGATTCAGCCTTGT
101 ORF125_21_15444025_15470065_15500094_15503881_RF OBD159_201 CTCTACCTGTATTGTTGGCTAATCAA
102 ORF125_21_15444025_15470065_15500094_15503881_RF OBD159_201 CTCTACCTGTATTGTTGGCTAATCAA
103 ORF127_5_127434266_127436041_127487600_127490915_RF OBD159_205 GGCAAAAGATTTATTAGGGACAACCA
104 ORF127_5_127434266_127436041_127487600_127490915_RF OBD159_205 GGCAAAAGATTTATTAGGGACAACCA
105 ORF13_1_207936305_207938059_207957832_207960627_RR OBD159_209 CAGAAATGTCAAAAGTAAGAGGCAAG
106 ORF13_1_207936305_207938059_207957832_207960627_RR OBD159_209 CAGAAATGTCAAAAGTAAGAGGCAAG
107 ORF13_11_49143461_49148959_49200052_49204610_FR OBD159_213 GGTTTCAGGACCACCCTCTACACCAA
108 ORF13_11_49143461_49148959_49200052_49204610_FR OBD159_213 GGTTTCAGGACCACCCTCTACACCAA
109 ORF13_12_83941063_83942894_83954032_83957600_FF OBD159_217 ACATATATTAATATAATAATGTA
110 ORF13_12_83941063_83942894_83954032_83957600_FF OBD159_217 ACATATATTAATATAATAATGTA
111 ORF13_13_98188349_98189635_98215516_98217335_FR OBD159_221 GAGCAGAACAGAAAGGAACTTGAGTA
112 ORF13_13_98188349_98189635_98215516_98217335_FR OBD159_221 GAGCAGAACAGAAAGGAACTTGAGTA
表1.b7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
53 OBD159_107 GCCCTTGCCCTGTCTCAGAATCT OBD159_105_107 -0.002149419
54 OBD159_107 GCCCTTGCCCTGTCTCAGAATCT OBD159_105_107 -0.002149419
55 OBD159_111 CAGATGTTGGTTTAGATGCTGGG OBD159_109_111 -0.002801859
56 OBD159_111 CAGATGTTGGTTTAGATGCTGGG OBD159_109_111 -0.002801859
57 OBD159_115 TTCTGTGGAGGACCTGGGAAATACTC OBD159_113_115 -0.00307575
58 OBD159_115 TTCTGTGGAGGACCTGGGAAATACTC OBD159_113_115 -0.00307575
59 OBD159_119 CCAGAAAGAATGATGAATGTGTTC OBD159_117_119 -0.001168646
60 OBD159_119 CCAGAAAGAATGATGAATGTGTTC OBD159_117_119 -0.001168646
61 OBD159_123 GCTGGCTGTCCTCTAAAACTCTTA OBD159_121_123 -0.003274843
62 OBD159_123 GCTGGCTGTCCTCTAAAACTCTTA OBD159_121_123 -0.003274843
63 OBD159_127 CCCATTGGCATTCAGTAGAACACTTC OBD159_125_127 -0.000325793
64 OBD159_127 CCCATTGGCATTCAGTAGAACACTTC OBD159_125_127 -0.000325793
65 OBD159_131 GATTGAAGGAGAGAGACTAAAGACGC OBD159_129_131 -0.002905869
66 OBD159_131 GATTGAAGGAGAGAGACTAAAGACGC OBD159_129_131 -0.002905869
67 OBD159_135 TTCAGTCAATCCTTTCAGAGAATA OBD159_133_135 -0.003158055
68 OBD159_135 TTCAGTCAATCCTTTCAGAGAATA OBD159_133_135 -0.003158055
69 OBD159_139 GAGTGGGTTGGGCAGATTAGGCA OBD159_137_139 -0.001264904
70 OBD159_139 GAGTGGGTTGGGCAGATTAGGCA OBD159_137_139 -0.001264904
71 OBD159_143 ATCTCAGGTAACTTGATTCACAAAG OBD159_141_143 -0.001918388
72 OBD159_143 ATCTCAGGTAACTTGATTCACAAAG OBD159_141_143 -0.001918388
73 OBD159_147 CAGGTATTGCCAGCCACAGCGTTTGA OBD159_145_147 -0.003019215
74 OBD159_147 CAGGTATTGCCAGCCACAGCGTTTGA OBD159_145_147 -0.003019215
75 OBD159_151 GACTCAAACAGTAAAATAGGGCACCA OBD159_149_151 -0.003218412
76 OBD159_151 GACTCAAACAGTAAAATAGGGCACCA OBD159_149_151 -0.003218412
77 OBD159_155 GCAAGTGCTCATCTCTAAACAACAAC OBD159_153_155 -0.000118105
78 OBD159_155 GCAAGTGCTCATCTCTAAACAACAAC OBD159_153_155 -0.000118105
79 OBD159_159 CTCCCTTTCCCAGTTTGAGCCCC OBD159_157_159 -0.00349468
80 OBD159_159 CTCCCTTTCCCAGTTTGAGCCCC OBD159_157_159 -0.00349468
81 OBD159_163 TTTATGAGAGTGTGGACAAAATAGGG OBD159_161_163 -0.000877317
82 OBD159_163 TTTATGAGAGTGTGGACAAAATAGGG OBD159_161_163 -0.000877317
83 OBD159_167 CCCCAACACAAACTGTCCTCAGGC OBD159_165_167 -0.005982598
84 OBD159_167 CCCCAACACAAACTGTCCTCAGGC OBD159_165_167 -0.005982598
85 OBD159_171 GTTTCACTTAGTTCTATTCTGATTT OBD159_169_171 -0.000811956
86 OBD159_171 GTTTCACTTAGTTCTATTCTGATTT OBD159_169_171 -0.000811956
87 OBD159_175 AGCCTGGGTAACAGAGTGAGACT OBD159_173_175 -0.001474355
88 OBD159_175 AGCCTGGGTAACAGAGTGAGACT OBD159_173_175 -0.001474355
89 OBD159_179 AGAGTGTTGACTGATGAAGGGCTC OBD159_177_179 -0.002586393
90 OBD159_179 AGAGTGTTGACTGATGAAGGGCTC OBD159_177_179 -0.002586393
91 OBD159_183 CTAACATTTCTTTTCTCCACAGTA OBD159_181_183 -0.003333301
92 OBD159_183 CTAACATTTCTTTTCTCCACAGTA OBD159_181_183 -0.003333301
93 OBD159_187 TTTGGCTGGAGCACGGAGTCTGC OBD159_185_187 -0.001801783
94 OBD159_187 TTTGGCTGGAGCACGGAGTCTGC OBD159_185_187 -0.001801783
95 OBD159_191 CTCCACTTCTACCACCACGAGTA OBD159_189_191 -0.002029191
96 OBD159_191 CTCCACTTCTACCACCACGAGTA OBD159_189_191 -0.002029191
97 OBD159_195 TTTCTGGAGCATTGTATGTCAACT OBD159_193_195 -0.002251075
98 OBD159_195 TTTCTGGAGCATTGTATGTCAACT OBD159_193_195 -0.002251075
99 OBD159_199 GATGACTGTTTTCAGAGACAATGGAA OBD159_197_199 -0.001778734
100 OBD159_199 GATGACTGTTTTCAGAGACAATGGAA OBD159_197_199 -0.001778734
101 OBD159_203 TTTTCCTGTCAGTGAACACCGTG OBD159_201_203 -0.000267413
102 OBD159_203 TTTTCCTGTCAGTGAACACCGTG OBD159_201_203 -0.000267413
103 OBD159_207 TTGGCATAAAGCAGGGCTCCAGGAAT OBD159_205_207 -0.002392578
104 OBD159_207 TTGGCATAAAGCAGGGCTCCAGGAAT OBD159_205_207 -0.002392578
105 OBD159_211 GCTTCCTCTGCCCCATCTACAAACAT OBD159_209_211 -0.004107822
106 OBD159_211 GCTTCCTCTGCCCCATCTACAAACAT OBD159_209_211 -0.004107822
107 OBD159_215 CCTACCCAAATAAGACTCATCCCAAC OBD159_213_215 -0.002783152
108 OBD159_215 CCTACCCAAATAAGACTCATCCCAAC OBD159_213_215 -0.002783152
109 OBD159_219 TTGCAACTAACCATGAAGAA OBD159_217_219 -0.001155074
110 OBD159_219 TTGCAACTAACCATGAAGAA OBD159_217_219 -0.001155074
111 OBD159_223 TAGACAGAACAGGCAGGCAGTTGGAC OBD159_221_223 -0.002281455
112 OBD159_223 TAGACAGAACAGGCAGGCAGTTGGAC OBD159_221_223 -0.002281455
表1.b8
   基因
53 ANKRD18A; CNTNAP3
54 ANKRD18A; CNTNAP3
55 RP5-972B16.2; RPGR; rs5963409; rs771214648; rs606231180; rs606231181; rs137852551; rs267607019; rs730882261; rs398122960; rs527236108; rs869312185; rs1060501181; rs62635004; rs771039023; rs527236109; rs62640593; rs527236112; rs62640590; rs62640589; rs527236111; rs62640587; rs62642057; rs878853374; rs138018739; rs62650220; rs62638651; rs62650218; rs137852550; rs62638646; rs62638644; rs62638643; rs62638637; rs62638636; rs111631988; rs62638634; rs62638630; rs62638629
56 RP5-972B16.2; RPGR; rs5963409; rs771214648; rs606231180; rs606231181; rs137852551; rs267607019; rs730882261; rs398122960; rs527236108; rs869312185; rs1060501181; rs62635004; rs771039023; rs527236109; rs62640593; rs527236112; rs62640590; rs62640589; rs527236111; rs62640587; rs62642057; rs878853374; rs138018739; rs62650220; rs62638651; rs62650218; rs137852550; rs62638646; rs62638644; rs62638643; rs62638637; rs62638636; rs111631988; rs62638634; rs62638630; rs62638629
57 rs59014890; rs2337901
58 rs59014890; rs2337901
59 LINGO2; rs7851437
60 LINGO2; rs7851437
61 rs2337901; rs11897825
62 rs2337901; rs11897825
63 C3orf56; rs7610266
64 C3orf56; rs7610266
65 rs2337901; rs11897825
66 rs2337901; rs11897825
67 FKTN; FSD1L; SLC44A1
68 FKTN; FSD1L; SLC44A1
69 CTDSPL; PLCD1; VILL; rs7372209
70 CTDSPL; PLCD1; VILL; rs7372209
71 SLITRK5
72 SLITRK5
73 MAP2; rs146432517; rs9288410
74 MAP2; rs146432517; rs9288410
75 rs7529073; rs4342822
76 rs7529073; rs4342822
77 C8orf48
78 C8orf48
79 rs7542939
80 rs7542939
81 FMN2; rs727502861; rs727502860
82 FMN2; rs727502861; rs727502860
83 LSM10; OSCP1
84 LSM10; OSCP1
85 CAPS2; KCNC2
86 CAPS2; KCNC2
87 NIN; rs387907308; rs146291102
88 NIN; rs387907308; rs146291102
89 E2F6; GREB1; rs77294520
90 E2F6; GREB1; rs77294520
91 GAFA3; PGM2
92 GAFA3; PGM2
93 ANKRD18A; CNTNAP3
94 ANKRD18A; CNTNAP3
95 PLS3; rs201386833
96 PLS3; rs201386833
97 RP5-972B16.2; RPGR; rs5963409; rs771214648; rs606231180; rs606231181; rs137852551; rs267607019; rs730882261; rs398122960; rs527236108; rs869312185; rs1060501181; rs62635004; rs771039023; rs527236109; rs62640593; rs527236112; rs62640590; rs62640589; rs527236111; rs62640587; rs62642057; rs878853374; rs138018739; rs62650220; rs62638651; rs62650218; rs137852550; rs62638646; rs62638644; rs62638643; rs62638637; rs62638636; rs111631988; rs62638634; rs62638630; rs62638629
98 RP5-972B16.2; RPGR; rs5963409; rs771214648; rs606231180; rs606231181; rs137852551; rs267607019; rs730882261; rs398122960; rs527236108; rs869312185; rs1060501181; rs62635004; rs771039023; rs527236109; rs62640593; rs527236112; rs62640590; rs62640589; rs527236111; rs62640587; rs62642057; rs878853374; rs138018739; rs62650220; rs62638651; rs62650218; rs137852550; rs62638646; rs62638644; rs62638643; rs62638637; rs62638636; rs111631988; rs62638634; rs62638630; rs62638629
99 TBX18; rs72912698; rs760905589; rs869320679; rs797045022; rs77693245
100 TBX18; rs72912698; rs760905589; rs869320679; rs797045022; rs77693245
101 rs1736020; rs1297265; rs2823286; rs2823288; rs2823310
102 rs1736020; rs1297265; rs2823286; rs2823288; rs2823310
103 MEGF10; rs794726677; rs387907071; rs387907072; rs199750143; rs794726678; rs989552169
104 MEGF10; rs794726677; rs387907071; rs387907072; rs199750143; rs794726678; rs989552169
105 rs2745959; rs2745967; rs11578508
106 rs2745959; rs2745967; rs11578508
107 FOLH1; rs202676; rs368939818; rs61886492; rs770894245; rs747052707; rs202680
108 FOLH1; rs202676; rs368939818; rs61886492; rs770894245; rs747052707; rs202680
109 rs11116045; rs1545843
110 rs11116045; rs1545843
111 FARP1; RNF113B
112 FARP1; RNF113B
表1.b9
   探針 基因座
113 ORF13_16_10047306_10049395_10119747_10125313_FF GRIN2A; rs7192557
114 ORF13_16_10047306_10049395_10119747_10125313_FF GRIN2A; rs7192557
115 ORF13_19_46459835_46460902_46479838_46481514_RF PNMAL1; PNMAL2; PPP5D1
116 ORF13_19_46459835_46460902_46479838_46481514_RF PNMAL1; PNMAL2; PPP5D1
117 ORF13_21_41872387_41876215_41926859_41930173_RR C2CD2; PRDM15; ZBTB21; rs451390
118 ORF13_21_41872387_41876215_41926859_41930173_RR C2CD2; PRDM15; ZBTB21; rs451390
119 ORF13_22_16921135_16923046_16987493_16991720_FR GAB4; rs41433045
120 ORF13_22_16921135_16923046_16987493_16991720_FR GAB4; rs41433045
121 ORF13_3_65738736_65743505_65758131_65766427_RR MAGI1; rs11924265
122 ORF13_3_65738736_65743505_65758131_65766427_RR MAGI1; rs11924265
123 ORF13_3_65738736_65743505_65827279_65831993_RR MAGI1; rs7633294; rs11924265; rs1909492; rs145965284
124 ORF13_3_65738736_65743505_65827279_65831993_RR MAGI1; rs7633294; rs11924265; rs1909492; rs145965284
125 ORF13_7_79409384_79415984_79434265_79448888_FF MAGI2; rs1135402912
126 ORF13_7_79409384_79415984_79434265_79448888_FF MAGI2; rs1135402912
127 ORF13_8_10137237_10138418_10247633_10250634_RR MSRA; rs7001567; rs10107815; rs73191547; rs17749155; rs2975735
128 ORF13_8_10137237_10138418_10247633_10250634_RR MSRA; rs7001567; rs10107815; rs73191547; rs17749155; rs2975735
129 ORF130_3_16438382_16444965_16496760_16499694_FR RFTN1; rs3856834
130 ORF130_3_16438382_16444965_16496760_16499694_FR RFTN1; rs3856834
131 ORF131_13_36625595_36628054_36670823_36673255_FR SERTM1; rs11619726
132 ORF131_13_36625595_36628054_36670823_36673255_FR SERTM1; rs11619726
133 ORF132_X_38848295_38850360_38907082_38913455_RR MID1IP1; rs199860
134 ORF132_X_38848295_38850360_38907082_38913455_RR MID1IP1; rs199860
135 ORF133_14_68255587_68260022_68325745_68327713_FF RAD51B; rs1570106; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566
136 ORF133_14_68255587_68260022_68325745_68327713_FF RAD51B; rs1570106; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566
137 ORF133_5_127388766_127390678_127434266_127436041_FR MEGF10; rs387907071; rs143954261; rs387907073; rs794726679; rs1057518682; rs794726677
138 ORF133_5_127388766_127390678_127434266_127436041_FR MEGF10; rs387907071; rs143954261; rs387907073; rs794726679; rs1057518682; rs794726677
139 ORF134_21_30984126_30988102_30998437_31002269_RF KRTAP19-8; rs8134605
140 ORF134_21_30984126_30988102_30998437_31002269_RF KRTAP19-8; rs8134605
141 ORF135_14_78345645_78349226_78398012_78400321_RF NRXN3; rs11624704
142 ORF135_14_78345645_78349226_78398012_78400321_RF NRXN3; rs11624704
143 ORF135_6_84752549_84755954_84775145_84786636_FR TBX18; rs869320679; rs797045022; rs77693245
144 ORF135_6_84752549_84755954_84775145_84786636_FR TBX18; rs869320679; rs797045022; rs77693245
145 ORF135_8_3431982_3435558_3460548_3464200_RF CSMD1; rs2938236; rs17066135
146 ORF135_8_3431982_3435558_3460548_3464200_RF CSMD1; rs2938236; rs17066135
147 ORF136_11_33584612_33595244_33612657_33615678_FF KIAA1549L; rs4755718; rs2076625
148 ORF136_11_33584612_33595244_33612657_33615678_FF KIAA1549L; rs4755718; rs2076625
149 ORF136_16_23139410_23143862_23210381_23212701_RR SCNN1G; USP31; rs137853342; rs5736
150 ORF136_16_23139410_23143862_23210381_23212701_RR SCNN1G; USP31; rs137853342; rs5736
151 ORF136_3_65835051_65839403_65852931_65856153_FF MAGI1; rs145965284
152 ORF136_3_65835051_65839403_65852931_65856153_FF MAGI1; rs145965284
153 ORF138_11_84067130_84068735_84120868_84126600_FR DLG2; rs790356
154 ORF138_11_84067130_84068735_84120868_84126600_FR DLG2; rs790356
155 ORF139_2_38148629_38155476_38206549_38210637_FR ATL2; CYP1B1
156 ORF139_2_38148629_38155476_38206549_38210637_FR ATL2; CYP1B1
157 ORF139_3_43868341_43870688_43889253_43893962_RR rs6441806; rs75594032
158 ORF139_3_43868341_43870688_43889253_43893962_RR rs6441806; rs75594032
159 ORF139_X_103107164_103111839_103149176_103158530_FF BEX4; NXF3
160 ORF139_X_103107164_103111839_103149176_103158530_FF BEX4; NXF3
161 ORF14_1_36409666_36411937_36433268_36434547_RR LSM10; OSCP1
162 ORF14_1_36409666_36411937_36433268_36434547_RR LSM10; OSCP1
163 ORF14_11_49143461_49148959_49200052_49204610_FF FOLH1; rs202676; rs368939818; rs61886492; rs770894245; rs747052707; rs202680
164 ORF14_11_49143461_49148959_49200052_49204610_FF FOLH1; rs202676; rs368939818; rs61886492; rs770894245; rs747052707; rs202680
165 ORF14_12_13672704_13680228_13739178_13742093_RF GRIN2B; rs1060499526; rs2192970; rs2284411; rs2268118
166 ORF14_12_13672704_13680228_13739178_13742093_RF GRIN2B; rs1060499526; rs2192970; rs2284411; rs2268118
167 ORF14_2_169020149_169021769_169079530_169081990_FR ABCB11; DHRS9; rs886043986; rs2161037
168 ORF14_2_169020149_169021769_169079530_169081990_FR ABCB11; DHRS9; rs886043986; rs2161037
169 ORF14_2_20283807_20286153_20303337_20304942_RF PUM2; rs111612372
170 ORF14_2_20283807_20286153_20303337_20304942_RF PUM2; rs111612372
171 ORF14_2_20303337_20304942_20379482_20381283_FF PUM2; rs585017
172 ORF14_2_20303337_20304942_20379482_20381283_FF PUM2; rs585017
173 ORF14_6_84752549_84755954_84775145_84786636_FR TBX18; rs869320679; rs797045022; rs77693245
174 ORF14_6_84752549_84755954_84775145_84786636_FR TBX18; rs869320679; rs797045022; rs77693245
175 ORF14_8_52230322_52233827_52248401_52253166_FF ST18; rs2360806
176 ORF14_8_52230322_52233827_52248401_52253166_FF ST18; rs2360806
177 ORF14_8_65560550_65562514_65658401_65661888_FR ARMC1; MTFR1; rs6991838
178 ORF14_8_65560550_65562514_65658401_65661888_FR ARMC1; MTFR1; rs6991838
179 ORF14_9_38648333_38653476_38681931_38686861_RF ANKRD18A; CNTNAP3
180 ORF14_9_38648333_38653476_38681931_38686861_RF ANKRD18A; CNTNAP3
181 ORF140_7_28717278_28719857_28731416_28736388_RR CREB5; rs56388170
182 ORF140_7_28717278_28719857_28731416_28736388_RR CREB5; rs56388170
183 ORF140_7_36976432_36980351_37039732_37049390_RR ELMO1; rs6942726; rs17170851
184 ORF140_7_36976432_36980351_37039732_37049390_RR ELMO1; rs6942726; rs17170851
185 ORF141_2_77514867_77519288_77576705_77580735_RF LRRTM4; rs61354037
186 ORF141_2_77514867_77519288_77576705_77580735_RF LRRTM4; rs61354037
187 ORF142_1_55502863_55511336_55533743_55538240_RR rs1998013; rs10888935
188 ORF142_1_55502863_55511336_55533743_55538240_RR rs1998013; rs10888935
189 ORF142_2_195535991_195542111_195583610_195589061_RF DNAH7; SLC39A10
190 ORF142_2_195535991_195542111_195583610_195589061_RF DNAH7; SLC39A10
191 ORF144_9_33273553_33275175_33317596_33319558_RR BAG1; CHMP5; NFX1
192 ORF144_9_33273553_33275175_33317596_33319558_RR BAG1; CHMP5; NFX1
193 ORF145_2_42093750_42101196_42140119_42144540_RF EML4; rs17029233
194 ORF145_2_42093750_42101196_42140119_42144540_RF EML4; rs17029233
195 ORF145_7_45364155_45370311_45421686_45426816_FR ADCY1; rs1294908
196 ORF145_7_45364155_45370311_45421686_45426816_FR ADCY1; rs1294908
197 ORF147_15_96308452_96311035_96328347_96331473_FR NR2F2; rs587777373; rs2398180
198 ORF147_15_96308452_96311035_96328347_96331473_FR NR2F2; rs587777373; rs2398180
199 ORF148_10_22661441_22663284_22705207_22709478_FF PIP4K2A; rs1409395; rs370356098
200 ORF148_10_22661441_22663284_22705207_22709478_FF PIP4K2A; rs1409395; rs370356098
201 ORF148_2_198067347_198074546_198099686_198102962_FR PLCL1; rs7587251; rs6745726; rs1368989; rs12105927; rs7590828; rs1866666; rs1036333; rs2164068; rs1064213; rs11684176
202 ORF148_2_198067347_198074546_198099686_198102962_FR PLCL1; rs7587251; rs6745726; rs1368989; rs12105927; rs7590828; rs1866666; rs1036333; rs2164068; rs1064213; rs11684176
203 ORF15_10_76403646_76410014_76480867_76489182_RR C10orf11; rs10509373; rs11593840
204 ORF15_10_76403646_76410014_76480867_76489182_RR C10orf11; rs10509373; rs11593840
205 ORF15_2_66539108_66541258_66592400_66595314_RR MEIS1; rs10865355; rs11897119; rs2300478; rs2300481
206 ORF15_2_66539108_66541258_66592400_66595314_RR MEIS1; rs10865355; rs11897119; rs2300478; rs2300481
207 ORF15_8_10100695_10103743_10173552_10175271_FF MSRA; rs73191547; rs10087178; rs10107815
208 ORF15_8_10100695_10103743_10173552_10175271_FF MSRA; rs73191547; rs10087178; rs10107815
209 ORF15_8_65560550_65562514_65637133_65640837_FR ARMC1; rs6991838
210 ORF15_8_65560550_65562514_65637133_65640837_FR ARMC1; rs6991838
211 ORF151_14_106693397_106698909_106739902_106745380_FF rs2337406; rs11846409
212 ORF151_14_106693397_106698909_106739902_106745380_FF rs2337406; rs11846409
表1.c1
   Probe_Count _Total Probe_Count _Sig HyperG_Stats
113 105 2; 1 0.137861813; 0.050084955
114 105 2; 1 0.137861813; 0.050084955
115 28; 32; 32 3; 4; 3; 4; 3; 4 0.071800115; 0.02285211; 0.09275567; 0.033810966; 0.09275567; 0.033810966
116 28; 32; 32 3; 4; 3; 4; 3; 4 0.071800115; 0.02285211; 0.09275567; 0.033810966; 0.09275567; 0.033810966
117 42; 25; 43 1; 1; 1; 1; 1; 1 0.320791853; 0.303213711; 0.375519541; 0.375121431; 0.315614698; 0.297350686
118 42; 25; 43 1; 1; 1; 1; 1; 1 0.320791853; 0.303213711; 0.375519541; 0.375121431; 0.315614698; 0.297350686
119 19 1; 1 0.362286681; 0.369026848
120 19 1; 1 0.362286681; 0.369026848
121 55 5; 5 0.042810093; 0.05348201
122 55 5; 5 0.042810093; 0.05348201
123 55 5; 5 0.042810093; 0.05348201
124 55 5; 5 0.042810093; 0.05348201
125 18 1; 1 0.357137933; 0.364965787
126 18 1; 1 0.357137933; 0.364965787
127 115 4; 4 0.193790369; 0.18374459
128 115 4; 4 0.193790369; 0.18374459
129 55 2; 3 0.274632664; 0.209439509
130 55 2; 3 0.274632664; 0.209439509
131 29 2; 2 0.211050406; 0.22548219
132 29 2; 2 0.211050406; 0.22548219
133 10 1; 1 0.272678156; 0.285987033
134 10 1; 1 0.272678156; 0.285987033
135 17 3; 2 0.023054538; 0.126473611
136 17 3; 2 0.023054538; 0.126473611
137 26 3; 3 0.061689421; 0.072111
138 26 3; 3 0.061689421; 0.072111
139 60 2; 2 0.268298503; 0.259153243
140 60 2; 2 0.268298503; 0.259153243
141 41 1; 1 0.325868449; 0.309016356
142 41 1; 1 0.325868449; 0.309016356
143 20 4; 5 0.005899409; 0.001067155
144 20 4; 5 0.005899409; 0.001067155
145 34 1; 1 0.357029649; 0.346365974
146 34 1; 1 0.357029649; 0.346365974
147 65 1; 2 0.198659276; 0.245566966
148 65 1; 2 0.198659276; 0.245566966
149 26; 18 2; 1; 1; 1 0.19032457; 0.373699919; 0.357137933; 0.364965787
150 26; 18 2; 1; 1; 1 0.19032457; 0.373699919; 0.357137933; 0.364965787
151 55 5; 5 0.042810093; 0.05348201
152 55 5; 5 0.042810093; 0.05348201
153 22 3; 3 0.042821316; 0.050708849
154 22 3; 3 0.042821316; 0.050708849
155 23; 34 4; 3; 4; 3 0.009574125; 0.055866229; 0.0324282; 0.117734198
156 23; 34 4; 3; 4; 3 0.009574125; 0.055866229; 0.0324282; 0.117734198
157 NA NA NA
158 NA NA NA
159 17; 17 1; 2; 1; 2 0.350975055; 0.126473611; 0.350975055; 0.126473611
160 17; 17 1; 2; 1; 2 0.350975055; 0.126473611; 0.350975055; 0.126473611
161 124; 112 3; 3; 3; 3 0.149414204; 0.126913559; 0.17713842; 0.156487188
162 124; 112 3; 3; 3; 3 0.149414204; 0.126913559; 0.17713842; 0.156487188
163 25 3; 4 0.05677955; 0.016055763
164 25 3; 4 0.05677955; 0.016055763
165 60 1; 2 0.22379944; 0.259153243
166 60 1; 2 0.22379944; 0.259153243
167 28; 49 2; 2; 2; 3 0.204457601; 0.219149094; 0.276096976; 0.190339907
168 28; 49 2; 2; 2; 3 0.204457601; 0.219149094; 0.276096976; 0.190339907
169 54 5; 6 0.040491239; 0.018151611
170 54 5; 6 0.040491239; 0.018151611
171 54 5; 6 0.040491239; 0.018151611
172 54 5; 6 0.040491239; 0.018151611
173 20 4; 5 0.005899409; 0.001067155
174 20 4; 5 0.005899409; 0.001067155
175 78 2; 4 0.222357541; 0.186212358
176 78 2; 4 0.222357541; 0.186212358
177 48; 28 5; 4; 2; 1 0.02780594; 0.092112824; 0.204457601; 0.369266824
178 48; 28 5; 4; 2; 1 0.02780594; 0.092112824; 0.204457601; 0.369266824
179 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
180 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
181 54 3; 3 0.193670022; 0.206710786
182 54 3; 3 0.193670022; 0.206710786
183 135 4; 2 0.167299602; 0.052146884
184 135 4; 2 0.167299602; 0.052146884
185 9 3; 2 0.00391071; 0.047199169
186 9 3; 2 0.00391071; 0.047199169
187 NA NA NA
188 NA NA NA
189 61; 81 2; 3; 3; 3 0.26657373; 0.222001213; 0.227770757; 0.222648484
190 61; 81 2; 3; 3; 3 0.26657373; 0.222001213; 0.227770757; 0.222648484
191 12; 22; 28 4; 1; 5; 1; 5; 1 0.000827358; 0.314913912; 0.001196845; 0.375573766; 0.003522831; 0.369266824
192 12; 22; 28 4; 1; 5; 1; 5; 1 0.000827358; 0.314913912; 0.001196845; 0.375573766; 0.003522831; 0.369266824
193 35 1; 1 0.353195365; 0.341533433
194 35 1; 1 0.353195365; 0.341533433
195 30 2; 2 0.21731878; 0.231426351
196 30 2; 2 0.21731878; 0.231426351
197 62 3; 3 0.214894644; 0.223472567
198 62 3; 3 0.214894644; 0.223472567
199 51 1; 1 0.272236181; 0.249886334
200 51 1; 1 0.272236181; 0.249886334
201 27 1; 2 0.374553651; 0.212429916
202 27 1; 2 0.374553651; 0.212429916
203 76 4; 4 0.169506823; 0.182516854
204 76 4; 4 0.169506823; 0.182516854
205 57 4; 2 0.110951788; 0.26588291
206 57 4; 2 0.110951788; 0.26588291
207 115 4; 4 0.193790369; 0.18374459
208 115 4; 4 0.193790369; 0.18374459
209 48 5; 4 0.02780594; 0.092112824
210 48 5; 4 0.02780594; 0.092112824
211 NA NA NA
212 NA NA NA
表1.c2
   FDR_HyperG Percent_Sig logFC AveExpr
113 0.375519541; 0.376115439 1.9; 0.95 0.642054929 0.642054929
114 0.375519541; 0.376115439 1.9; 0.95 0.534888101 0.534888101
115 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.71; 14.29; 9.38; 12.5; 9.38; 12.5 0.559389203 0.559389203
116 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.71; 14.29; 9.38; 12.5; 9.38; 12.5 0.527003029 0.527003029
117 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.38; 2.38; 4; 4; 2.33; 2.33 0.777909524 0.777909524
118 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.38; 2.38; 4; 4; 2.33; 2.33 0.685362008 0.685362008
119 0.375519541; 0.376115439 5.26; 5.26 0.69171806 0.69171806
120 0.375519541; 0.376115439 5.26; 5.26 0.674817566 0.674817566
121 0.375519541; 0.376115439 9.09; 9.09 0.833849291 0.833849291
122 0.375519541; 0.376115439 9.09; 9.09 0.695864718 0.695864718
123 0.375519541; 0.376115439 9.09; 9.09 0.608567925 0.608567925
124 0.375519541; 0.376115439 9.09; 9.09 0.574949497 0.574949497
125 0.375519541; 0.376115439 5.56; 5.56 0.639632985 0.639632985
126 0.375519541; 0.376115439 5.56; 5.56 0.536103928 0.536103928
127 0.375519541; 0.376115439 3.48; 3.48 0.525096445 0.525096445
128 0.375519541; 0.376115439 3.48; 3.48 0.501604871 0.501604871
129 0.375519541; 0.376115439 3.64; 5.45 0.629919082 0.629919082
130 0.375519541; 0.376115439 3.64; 5.45 0.546528148 0.546528148
131 0.375519541; 0.376115439 6.9; 6.9 0.611119135 0.611119135
132 0.375519541; 0.376115439 6.9; 6.9 0.590770741 0.590770741
133 0.375519541; 0.376115439 10; 10 0.834668158 0.834668158
134 0.375519541; 0.376115439 10; 10 0.631440161 0.631440161
135 0.375519541; 0.376115439 17.65; 11.76 0.680155782 0.680155782
136 0.375519541; 0.376115439 17.65; 11.76 0.664622124 0.664622124
137 0.375519541; 0.376115439 11.54; 11.54 0.607866815 0.607866815
138 0.375519541; 0.376115439 11.54; 11.54 0.552626553 0.552626553
139 0.375519541; 0.376115439 3.33; 3.33 0.669529858 0.669529858
140 0.375519541; 0.376115439 3.33; 3.33 0.665404676 0.665404676
141 0.375519541; 0.376115439 2.44; 2.44 0.592000703 0.592000703
142 0.375519541; 0.376115439 2.44; 2.44 0.574160237 0.574160237
143 0.242080288; 0.077749847 20; 25 0.635545627 0.635545627
144 0.242080288; 0.077749847 20; 25 0.565387572 0.565387572
145 0.375519541; 0.376115439 2.94; 2.9 0.570456105 0.570456105
146 0.375519541; 0.376115439 2.94; 2.94 0.535588266 0.535588266
147 0.375519541; 0.376115439 1.54; 3.08 0.621664701 0.621664701
148 0.375519541; 0.376115439 1.54; 3.08 0.567979364 0.567979364
149 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.69; 3.85; 5.56; 5.56 0.786058889 0.786058889
150 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.69; 3.85; 5.56; 5.56 0.664874819 0.664874819
151 0.375519541; 0.376115439 9.09; 9.09 0.913306418 0.913306418
152 0.375519541; 0.376115439 9.09; 9.09 0.85049037 0.85049037
153 0.375519541; 0.376115439 13.64; 13.64 0.89651913 0.89651913
154 0.375519541; 0.376115439 13.64; 13.64 0.797428847 0.797428847
155 0.357661967; 0.376115439; 0.375519541; 0.376115439 17.39; 13.04; 11.76; 8.82 0.709322488 0.709322488
156 0.357661967; 0.376115439; 0.375519541; 0.376115439 17.39; 13.04; 11.76; 8.82 0.689453202 0.689453202
157 NA NA 0.8399913 0.8399913
158 NA NA 0.71642198 0.71642198
159 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 11.76; 5.88; 11.76 1.020404508 1.020404508
160 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 11.76; 5.88; 11.76 0.96486656 0.96486656
161 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.42; 2.42; 2.68; 2.68 0.600126118 0.600126118
162 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.42; 2.42; 2.68; 2.68 0.587561129 0.587561129
163 0.375519541; 0.376115439 12; 16 0.752070326 0.752070326
164 0.375519541; 0.376115439 12; 16 0.646095977 0.646095977
165 0.375519541; 0.376115439 1.67; 3.33 0.772231914 0.772231914
166 0.375519541; 0.376115439 1.67; 3.33 0.756505991 0.756505991
167 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.14; 7.14; 4.08; 6.12 0.707732194 0.707732194
168 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.14; 7.14; 4.08; 6.12 0.647895485 0.647895485
169 0.375519541; 0.376115439 9.26; 11.11 0.634884917 0.634884917
170 0.375519541; 0.376115439 9.26; 11.11 0.537608783 0.537608783
171 0.375519541; 0.376115439 9.26; 11.11 0.873814619 0.873814619
172 0.375519541; 0.376115439 9.26; 11.11 0.66582529 0.66582529
173 0.242080288; 0.077749847 20; 25 0.592740002 0.592740002
174 0.242080288; 0.077749847 20; 25 0.567930462 0.567930462
175 0.375519541; 0.376115439 2.56; 5.13 0.650656625 0.650656625
176 0.375519541; 0.376115439 2.56; 5.13 0.57605457 0.57605457
177 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.42; 8.33; 7.14; 3.57 0.882684402 0.882684402
178 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.42; 8.33; 7.14; 3.57 0.78560934 0.78560934
179 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.56533113 0.56533113
180 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.493648488 0.493648488
181 0.375519541; 0.376115439 5.56; 5.56 0.899280884 0.899280884
182 0.375519541; 0.376115439 5.56; 5.56 0.754589946 0.754589946
183 0.375519541; 0.376115439 2.96; 1.48 0.54191602 0.54191602
184 0.375519541; 0.376115439 2.96; 1.48 0.536557556 0.536557556
185 0.185936467; 0.376115439 33.33; 22.22 0.528816654 0.528816654
186 0.185936467; 0.376115439 33.33; 22.22 0.510412189 0.510412189
187 NA NA 0.570106196 0.570106196
188 NA NA 0.547188195 0.547188195
189 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.28; 4.92; 3.7; 3.7 0.925148196 0.925148196
190 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.28; 4.92; 3.7; 3.7 0.860859073 0.860859073
191 0.069549998; 0.376115439; 0.069549998; 0.376115439; 0.184244052; 0.376115439 33.33; 8.33; 22.73; 4.55; 17.86; 3.57 0.830272909 0.830272909
192 0.069549998; 0.376115439; 0.069549998; 0.376115439; 0.184244052; 0.376115439 33.33; 8.33; 22.73; 4.55; 17.86; 3.57 0.605028673 0.605028673
193 0.375519541; 0.376115439 2.86; 2.86 0.629699885 0.629699885
194 0.375519541; 0.376115439 2.86; 2.86 0.608805138 0.608805138
195 0.375519541; 0.376115439 6.67; 6.67 0.688184104 0.688184104
196 0.375519541; 0.376115439 6.67; 6.67 0.631925311 0.631925311
197 0.375519541; 0.376115439 4.84; 4.84 0.66816546 0.66816546
198 0.375519541; 0.376115439 4.84; 4.84 0.496321797 0.496321797
199 0.375519541; 0.376115439 1.96; 1.96 0.559048166 0.559048166
200 0.375519541; 0.376115439 1.96; 1.96 0.546506729 0.546506729
201 0.375519541; 0.376115439 3.7; 7.41 0.660605853 0.660605853
202 0.375519541; 0.376115439 3.7; 7.41 0.620982224 0.620982224
203 0.375519541; 0.376115439 5.26; 5.26 0.548392035 0.548392035
204 0.375519541; 0.376115439 5.26; 5.26 0.544462095 0.544462095
205 0.375519541; 0.376115439 7.02; 3.51 0.633583316 0.633583316
206 0.375519541; 0.376115439 7.02; 3.51 0.527645503 0.527645503
207 0.375519541; 0.376115439 3.48; 3.48 0.5396147 0.5396147
208 0.375519541; 0.376115439 3.48; 3.48 0.532813708 0.532813708
209 0.375519541; 0.376115439 10.42; 8.33 0.694623516 0.694623516
210 0.375519541; 0.376115439 10.42; 8.33 0.669053043 0.669053043
211 NA NA 0.677090319 0.677090319
212 NA NA 0.525571424 0.525571424
表1.c3
   t P值 adj.P.Val B FC FC_1 LS
113 12.29657599 0.0000000389 0.0000112 9.28555547 1.560550375 1.560550375 1
114 9.863570244 0.000000421 0.0000233 6.888532755 1.448829775 1.448829775 1
115 8.570462938 0.00000186 0.000059 5.366520046 1.473645185 1.473645185 1
116 7.239748622 0.0000106 0.000327829 3.648069676 1.440932774 1.440932774 1
117 12.23174867 0.0000000397 0.00000589 9.265915789 1.714644539 1.714644539 1
118 8.825906239 0.00000141 0.0000917 5.705820315 1.608105445 1.608105445 1
119 7.339515775 0.00000926 0.000301666 3.786888778 1.615205871 1.615205871 1
120 8.215028312 0.00000289 0.0000778 4.915625384 1.59639489 1.59639489 1
121 19.14681066 0.000000000252 0.00000103 13.97183644 1.782434783 1.782434783 1
122 14.54846247 0.00000000561 0.00000218 11.18765775 1.619855045 1.619855045 1
123 11.04549051 0.000000127 0.0000213 8.119748088 1.524744937 1.524744937 1
124 15.11740631 0.00000000362 0.00000171 11.60988606 1.489625316 1.489625316 1
125 7.756918889 0.00000532 0.000211946 4.353501606 1.557932778 1.557932778 1
126 8.756135369 0.00000149 0.0000515 5.596232128 1.450051287 1.450051287 1
127 18.04698486 0.000000000499 0.00000152 13.3693963 1.439029777 1.439029777 1
128 11.23507651 0.000000102 0.00000993 8.323155136 1.415787626 1.415787626 1
129 16.15349133 0.00000000170 0.00000121 12.33518156 1.547478196 1.547478196 1
130 12.83197859 0.0000000242 0.00000874 9.748081285 1.460566603 1.460566603 1
131 13.87996531 0.00000001 0.0000055 10.59694422 1.527443626 1.527443626 1
132 11.16934802 0.000000109 0.0000103 8.258187013 1.506051121 1.506051121 1
133 15.50546579 0.00000000285 0.00000294 11.78233016 1.783446771 1.783446771 1
134 7.456443365 0.00000774 0.000146321 3.901820902 1.549110612 1.549110612 1
135 9.171197371 0.000000915 0.0000379 6.095816878 1.602312763 1.602312763 1
136 15.72367178 0.00000000243 0.00000276 11.93052546 1.585153029 1.585153029 1
137 8.352727895 0.00000244 0.0000699 5.092073514 1.524004133 1.524004133 1
138 8.826468071 0.00000141 0.0000917 5.706495712 1.46675362 1.46675362 1
139 9.778292783 0.000000476 0.0000471 6.801498437 1.590554557 1.590554557 1
140 16.33513633 0.00000000149 0.00000114 12.45688849 1.586013087 1.586013087 1
141 6.305428984 0.0000401 0.000788065 2.28193028 1.507335644 1.507335644 1
142 12.84449383 0.000000023 0.00000441 9.808591378 1.488810605 1.488810605 1
143 13.38587721 0.0000000151 0.00000688 10.20566573 1.553525182 1.553525182 1
144 12.59163536 0.0000000287 0.000005 9.587875271 1.479784992 1.479784992 1
145 9.442845356 0.000000671 0.0000311 6.412723986 1.484992974 1.484992974 1
146 7.596849376 0.00000656 0.000239887 4.138885561 1.449533088 1.449533088 1
147 11.62558761 0.0000000725 0.0000153 8.67583038 1.538649579 1.538649579 1
148 15.26126084 0.00000000325 0.00000161 11.71387103 1.482445805 1.482445805 1
149 6.105674865 0.0000541 0.000962931 1.973943798 1.724357475 1.724357475 1
150 8.371648256 0.00000238 0.0000689 5.116142152 1.585430702 1.585430702 1
151 15.88124985 0.00000000217 0.00000259 12.03604736 1.883356898 1.883356898 1
152 18.19418346 0.000000000429 0.000000653 13.61809441 1.803113697 1.803113697 1
153 20.04156697 0.000000000148 0.00000103 14.42944596 1.86156905 1.86156905 1
154 12.881791 0.0000000222 0.00000435 9.840773338 1.738000921 1.738000921 1
155 12.3642085 0.0000000366 0.0000108 9.345123175 1.635036099 1.635036099 1
156 9.152158447 0.000000935 0.0000385 6.073312254 1.612672181 1.612672181 1
157 19.10878979 0.000000000257 0.00000103 13.95176635 1.790039347 1.790039347 1
158 10.43275288 0.000000229 0.0000161 7.504665857 1.643101929 1.643101929 1
159 21.00404466 0.0000000000807 0.00000039 15.12202904 2.028487635 2.028487635 1
160 12.79168312 0.0000000251 0.00000885 9.713978326 1.951882976 1.951882976 1
161 21.66770766 0.0000000000597 0.000000663 15.19411522 1.515849073 1.515849073 1
162 13.98057328 0.00000000883 0.00000269 10.74792677 1.502704282 1.502704282 1
163 13.876189 0.00000000961 0.00000281 10.66502031 1.684208004 1.684208004 1
164 11.81234601 0.0000000608 0.0000138 8.849033958 1.564927669 1.564927669 1
165 11.53329799 0.0000000792 0.0000162 8.589212532 1.707909954 1.707909954 1
166 14.31826594 0.00000000673 0.00000237 11.01167664 1.689394186 1.689394186 1
167 11.24102356 0.000000105 0.000019 8.31031525 1.633234778 1.633234778 1
168 14.54104319 0.00000000565 0.00000218 11.18203304 1.566880858 1.566880858 1
169 19.3999006 0.000000000204 0.000000503 14.29706452 1.552813878 1.552813878 1
170 10.07154199 0.000000347 0.000039 7.12001582 1.451564605 1.451564605 1
171 15.60748179 0.00000000264 0.00000286 11.85191731 1.832501804 1.832501804 1
172 10.83942215 0.000000151 0.0000126 7.926551142 1.586475553 1.586475553 1
173 11.54164794 0.0000000757 0.00000841 8.621484254 1.508108266 1.508108266 1
174 9.732052458 0.000000501 0.0000487 6.750493527 1.482395556 1.482395556 1
175 9.854433288 0.000000438 0.0000448 6.885017151 1.569882546 1.569882546 1
176 9.330647052 0.000000762 0.0000339 6.282774663 1.490766774 1.490766774 1
177 12.25442736 0.0000000405 0.0000114 9.24826214 1.843802848 1.843802848 1
178 12.90483498 0.0000000218 0.00000431 9.860609412 1.723820242 1.723820242 1
179 6.227858807 0.000045 0.000850219 2.163006432 1.4797271 1.4797271 1
180 7.44435462 0.00000786 0.000147933 3.885074196 1.408001126 1.408001126 1
181 13.07374694 0.0000000196 0.00000788 9.950348451 1.865136068 1.865136068 1
182 19.91676727 0.000000000150 0.000000464 14.57215105 1.687151988 1.687151988 1
183 10.98867694 0.000000135 0.0000221 8.063765262 1.455904797 1.455904797 1
184 16.12532926 0.00000000173 0.00000121 12.31617161 1.4505073 1.4505073 1
185 9.761017839 0.000000471 0.000025 6.774194723 1.442745323 1.442745323 1
186 8.292905428 0.00000269 0.000138197 5.048700551 1.424457116 1.424457116 1
187 14.16188606 0.00000000763 0.00000252 10.89037664 1.48463285 1.48463285 1
188 10.9669012 0.000000138 0.0000224 8.042234039 1.46123498 1.46123498 1
189 12.41082654 0.0000000351 0.0000105 9.385986987 1.898879288 1.898879288 1
190 15.0227439 0.00000000389 0.00000178 11.54085912 1.816119422 1.816119422 1
191 7.831039921 0.00000472 0.000106638 4.411447921 1.778021672 1.778021672 1
192 6.383716681 0.0000357 0.000729587 2.40108624 1.521008982 1.521008982 1
193 14.04269586 0.00000000839 0.00000263 10.796955 1.547243096 1.547243096 1
194 9.786691524 0.000000472 0.0000468 6.810739504 1.524995661 1.524995661 1
195 11.80999999 0.0000000609 0.0000138 8.846875259 1.611254183 1.611254183 1
196 10.87786687 0.000000145 0.0000123 7.965676533 1.549631635 1.549631635 1
197 12.34739858 0.0000000372 0.0000109 9.330349145 1.589051035 1.589051035 1
198 19.10074585 0.000000000244 0.000000514 14.13358838 1.410612566 1.410612566 1
199 11.15023282 0.000000111 0.0000104 8.239225146 1.473296873 1.473296873 1
200 10.17124154 0.000000312 0.0000369 7.226393871 1.46054492 1.46054492 1
201 10.98010134 0.000000136 0.0000222 8.05529085 1.580746311 1.580746311 1
202 17.71105209 0.000000000586 0.000000747 13.330373 1.537921882 1.537921882 1
203 22.07702074 0.0000000000450 0.00000032 15.62922376 1.462454799 1.462454799 1
204 10.42317496 0.000000239 0.0000316 7.490992927 1.458476453 1.458476453 1
205 14.44991956 0.00000000607 0.00000227 11.11269518 1.551413559 1.551413559 1
206 14.9951486 0.00000000417 0.00000369 11.42604699 1.441574607 1.441574607 1
207 12.26156198 0.0000000386 0.00000581 9.292944196 1.453584258 1.453584258 1
208 16.76008538 0.00000000117 0.0000021 12.60248449 1.446748058 1.446748058 1
209 11.64102375 0.0000000688 0.00000796 8.716560039 1.618462027 1.618462027 1
210 8.321741849 0.0000026 0.000135064 5.085106196 1.590028961 1.590028961 1
211 8.075983057 0.00000353 0.000163981 4.771615491 1.598911756 1.598911756 1
212 11.47180426 0.0000000809 0.00000873 8.554190275 1.439503627 1.439503627 1
1.c4
      探針序列 探針位置
偵測到之環 60 mer Chr
113 mHC TTTATTGATTTTTTACTATTTTTTTTTTTCGACAATAAATGCAAAAAGTTTGAAAAAATC 16
114 sHC TTTATTGATTTTTTACTATTTTTTTTTTTCGACAATAAATGCAAAAAGTTTGAAAAAATC 16
115 sHC TTTTTAAAGAAGGTTTGTATCATATTTCTCGATATTATTCTATCAGTCCTGCAGTCCTGT 19
116 mHC TTTTTAAAGAAGGTTTGTATCATATTTCTCGATATTATTCTATCAGTCCTGCAGTCCTGT 19
117 sHC CAATATTTTCAGAGTCATAATATATACATCGAATAATTTTCACTTTCATCACATTCTGTA 21
118 mHC CAATATTTTCAGAGTCATAATATATACATCGAATAATTTTCACTTTCATCACATTCTGTA 21
119 mHC TACCTTTATTTTTGAAGCATATCTTCACTCGAAATTTAATTTAATTTTAATTAGCTTAAA 22
120 sHC TACCTTTATTTTTGAAGCATATCTTCACTCGAAATTTAATTTAATTTTAATTAGCTTAAA 22
121 mHC CCTTTCAATGTATTGTTACTGCTACTCATCGAGGAGATAAATCTCCCAGTCCTAGTTGGT 3
122 sHC CCTTTCAATGTATTGTTACTGCTACTCATCGAGGAGATAAATCTCCCAGTCCTAGTTGGT 3
123 mHC CCTTTCAATGTATTGTTACTGCTACTCATCGAAAGTTGATGCCAAATTGGGAAGTAAGAC 3
124 sHC CCTTTCAATGTATTGTTACTGCTACTCATCGAAAGTTGATGCCAAATTGGGAAGTAAGAC 3
125 mHC AATTGTATATTAGACTAGATTAGACTATTCGAATGTTAAATATGATTATTTGCTTTTTAT 7
126 sHC AATTGTATATTAGACTAGATTAGACTATTCGAATGTTAAATATGATTATTTGCTTTTTAT 7
127 mHC AACCAATTTTTTAAAATATGCTTTTAAGTCGATTGGATATGAACACTACCTGCTAAGTTA 8
128 sHC AACCAATTTTTTAAAATATGCTTTTAAGTCGATTGGATATGAACACTACCTGCTAAGTTA 8
129 sHC TTTAGTATTAGAAATGTTTTGGTCTTTATCGAAAGACACGTATGAGAAAGCTAACAGTAG 3
130 mHC TTTAGTATTAGAAATGTTTTGGTCTTTATCGAAAGACACGTATGAGAAAGCTAACAGTAG 3
131 mHC GGATCAAACCCTTCATATATACCAATTATCGAAATATGAATCATCTTTGTCCAGTATGGA 13
132 sHC GGATCAAACCCTTCATATATACCAATTATCGAAATATGAATCATCTTTGTCCAGTATGGA 13
133 mHC TTTTTTATATCATACTTTTGGTTTTAAATCGATTTCCTCTGTAAAATTATAGAATGGACT X
134 sHC TTTTTTATATCATACTTTTGGTTTTAAATCGATTTCCTCTGTAAAATTATAGAATGGACT X
135 sHC CACAAAATAACAAATATATAAGATATTTTCGAAGATTAATATCTACTCATAATGGTTAGA 14
136 mHC CACAAAATAACAAATATATAAGATATTTTCGAAGATTAATATCTACTCATAATGGTTAGA 14
137 sHC TCATCTTCTATAAAAATCATTTAATTAATCGATTTTTATTGCCAGAAACGACTCTTAAAG 5
138 mHC TCATCTTCTATAAAAATCATTTAATTAATCGATTTTTATTGCCAGAAACGACTCTTAAAG 5
139 mHC AATAACAATTCACCAAAATTTTAAACATTCGAATTTTTAAATTTATTTCTGTAAATAAAG 21
140 sHC AATAACAATTCACCAAAATTTTAAACATTCGAATTTTTAAATTTATTTCTGTAAATAAAG 21
141 mHC AAAGATTAGTTTCAAAATTTCTATAAACTCGATGGATATAGCAAACCAATTGGTTTCCCT 14
142 sHC AAAGATTAGTTTCAAAATTTCTATAAACTCGATGGATATAGCAAACCAATTGGTTTCCCT 14
143 mHC GGTATTTCTTTTATGTATGATATATTCTTCGAGTCGCTCAGAAGCGACCTAAAGAAGGCA 6
144 sHC GGTATTTCTTTTATGTATGATATATTCTTCGAGTCGCTCAGAAGCGACCTAAAGAAGGCA 6
145 sHC ATGCAGTTCATCAACTAGTGTGATGAACTCGAATGTGATCATGTAAGAGATCACTGTGTG 8
146 mHC ATGCAGTTCATCAACTAGTGTGATGAACTCGAATGTGATCATGTAAGAGATCACTGTGTG 8
147 mHC CTATATTTGCTTCATAATTTTTTCTTTTTCGACATTGAAGTGTATACCAGTCTACTTTTG 11
148 sHC CTATATTTGCTTCATAATTTTTTCTTTTTCGACATTGAAGTGTATACCAGTCTACTTTTG 11
149 mHC ATCAGTTTATTTTACTTTATTTTTTATTTCGAAAAAATGAAACGATACAGCAACATTGAG 16
150 sHC ATCAGTTTATTTTACTTTATTTTTTATTTCGAAAAAATGAAACGATACAGCAACATTGAG 16
151 mHC TTATATCATTATTTTATAATGTATTCCTTCGAAATATAAGTTAGTTAAAATTAAACATAA 3
152 sHC TTATATCATTATTTTATAATGTATTCCTTCGAAATATAAGTTAGTTAAAATTAAACATAA 3
153 mHC CTCATTATACTGAGTTTATTTGTTTTATTCGAATAACTATATCCTTACATTCAGTCACTA 11
154 sHC CTCATTATACTGAGTTTATTTGTTTTATTCGAATAACTATATCCTTACATTCAGTCACTA 11
155 mHC TCATAAAATAATAATTAACAAACATACATCGAACATACTAATCTTTTTACCAAGTGTTTG 2
156 sHC TCATAAAATAATAATTAACAAACATACATCGAACATACTAATCTTTTTACCAAGTGTTTG 2
157 mHC TAGCTGTTTAATTATCAATATATTAATTTCGATAATTTTCTCTCTTCCATTTTCTTTATT 3
158 sHC TAGCTGTTTAATTATCAATATATTAATTTCGATAATTTTCTCTCTTCCATTTTCTTTATT 3
159 sHC AATATATTTCTAAAATATGTAAATATATTCGATATATGTTTTATGAGTAAAGAAGCAGAT X
160 mHC AATATATTTCTAAAATATGTAAATATATTCGATATATGTTTTATGAGTAAAGAAGCAGAT X
161 mHC TGGTAAATTGGAGCAGGTGACCTGGGAGTCGAGGCAGCTGCAGGATTTAAATTGGCTGAG 1
162 sHC TGGTAAATTGGAGCAGGTGACCTGGGAGTCGAGGCAGCTGCAGGATTTAAATTGGCTGAG 1
163 sHC ATTTTTTTTTATTATTATACTTTTAAGTTCGAACTTCTTTATCTTTGTGGAAAACCCTCC 11
164 mHC ATTTTTTTTTATTATTATACTTTTAAGTTCGAACTTCTTTATCTTTGTGGAAAACCCTCC 11
165 mHC GTTCTCTGACTTTTTATACCTAAGATAATCGATATGAAAATGTTCTATTCTATTATCTCA 12
166 sHC GTTCTCTGACTTTTTATACCTAAGATAATCGATATGAAAATGTTCTATTCTATTATCTCA 12
167 mHC TATATTTAATTATAATTGTAACACAATGTCGAAGGAAAAATTAGGAAATAATTGTAAGAA 2
168 sHC TATATTTAATTATAATTGTAACACAATGTCGAAGGAAAAATTAGGAAATAATTGTAAGAA 2
169 sHC TATATGGTACATATTATACATATTTCTATCGAAGAAGAAGGATTAAAAAAACTGGGAGTA 2
170 mHC TATATGGTACATATTATACATATTTCTATCGAAGAAGAAGGATTAAAAAAACTGGGAGTA 2
171 mHC TATATGGTACATATTATACATATTTCTATCGAGAAATAAACTCATATATTTATGATCTAC 2
172 sHC TATATGGTACATATTATACATATTTCTATCGAGAAATAAACTCATATATTTATGATCTAC 2
173 sHC GGTATTTCTTTTATGTATGATATATTCTTCGAGTCGCTCAGAAGCGACCTAAAGAAGGCA 6
174 mHC GGTATTTCTTTTATGTATGATATATTCTTCGAGTCGCTCAGAAGCGACCTAAAGAAGGCA 6
175 mHC GTTTCTTTTTAAAGTAAATTAAATTTAATCGAAGTATGCACTGTAACTTCTATAATCTTA 8
176 sHC GTTTCTTTTTAAAGTAAATTAAATTTAATCGAAGTATGCACTGTAACTTCTATAATCTTA 8
177 mHC TATCTCTATGTAATAATCACTAAAAGTATCGAGCTACATACTATTATATATTTTCACAGT 8
178 sHC TATCTCTATGTAATAATCACTAAAAGTATCGAGCTACATACTATTATATATTTTCACAGT 8
179 mHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGAGAGCTGGTCTTGACGAGGTGTGCCTTGC 9
180 sHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGAGAGCTGGTCTTGACGAGGTGTGCCTTGC 9
181 mHC TATGAAAATATAAAAGAATATAAAGAGTTCGATTATGTGTCTTGAAAACAAGAATTGAGA 7
182 sHC TATGAAAATATAAAAGAATATAAAGAGTTCGATTATGTGTCTTGAAAACAAGAATTGAGA 7
183 mHC CTAATAATAATTATGCTGTTAAGCTCAATCGACAATAAATACTTAAAATTCACACGGTTT 7
184 sHC CTAATAATAATTATGCTGTTAAGCTCAATCGACAATAAATACTTAAAATTCACACGGTTT 7
185 sHC TATATATTAAGTTATACAACATGATATTTCGAAGGAAAAAATTGATATACAGAATGAAGC 2
186 mHC TATATATTAAGTTATACAACATGATATTTCGAAGGAAAAAATTGATATACAGAATGAAGC 2
187 sHC GTTATTATACTGCTAAATAATAAGATCCTCGAGCTTCACTTTTTATATATGTAAAATGGA 1
188 mHC GTTATTATACTGCTAAATAATAAGATCCTCGAGCTTCACTTTTTATATATGTAAAATGGA 1
189 mHC ATTTTTAATTATTAAAAAATAATGTTTTTCGACTTGTATTACCTCATGTAGTTCTCATAT 2
190 sHC ATTTTTAATTATTAAAAAATAATGTTTTTCGACTTGTATTACCTCATGTAGTTCTCATAT 2
191 sHC TTTAGGAAAATAAATCTGACCAAAAAATTCGAGGCCGCAGTAAGCTGTGTTCACACCACT 9
192 mHC TTTAGGAAAATAAATCTGACCAAAAAATTCGAGGCCGCAGTAAGCTGTGTTCACACCACT 9
193 sHC TTTAATCAGTTTCCTTTTTTTTTTTTTTTCGAAAAAAAAAAAAAGCCATTGAAGGGATTT 2
194 mHC TTTAATCAGTTTCCTTTTTTTTTTTTTTTCGAAAAAAAAAAAAAGCCATTGAAGGGATTT 2
195 mHC TTACTCACTTATTAGTCTATTAAGATTTTCGATTAAGTCTAATTTAGCACTTTCTCTTTT 7
196 sHC TTACTCACTTATTAGTCTATTAAGATTTTCGATTAAGTCTAATTTAGCACTTTCTCTTTT 7
197 mHC AAATAACTTACATATGGACATGAGTATATCGATATTGTTCCTTCCCATGTTTGTAAAAGG 15
198 sHC AAATAACTTACATATGGACATGAGTATATCGATATTGTTCCTTCCCATGTTTGTAAAAGG 15
199 sHC TCTGATATATATTTGCTAAGGTAGTAAATCGAAATACAAATTTTGGAATTGAAGGGAATT 10
200 mHC TCTGATATATATTTGCTAAGGTAGTAAATCGAAATACAAATTTTGGAATTGAAGGGAATT 10
201 mHC GTAAATATTACCATTAAAAACTGAAAAGTCGATTATCTCTTTATGACGTTTATTAGACAA 2
202 sHC GTAAATATTACCATTAAAAACTGAAAAGTCGATTATCTCTTTATGACGTTTATTAGACAA 2
203 sHC ACTCTTCAAAATTATAATTATCAACAATTCGAAGAATACCTTAAAGGTAATCATATGTAT 10
204 mHC ACTCTTCAAAATTATAATTATCAACAATTCGAAGAATACCTTAAAGGTAATCATATGTAT 10
205 sHC AAGGCAGGTGGATCATAAGGTCAGGAGATCGAAAAAAAAATAAAAAAATAAAAAAATAAA 2
206 mHC AAGGCAGGTGGATCATAAGGTCAGGAGATCGAAAAAAAAATAAAAAAATAAAAAAATAAA 2
207 sHC TTTAAAATGCTTTAAAATTGTTTAAATATCGATTCTAGAGGAAGTCAAATAAAACAATGG 8
208 mHC TTTAAAATGCTTTAAAATTGTTTAAATATCGATTCTAGAGGAAGTCAAATAAAACAATGG 8
209 sHC TATCTCTATGTAATAATCACTAAAAGTATCGAGTACATAGCTCTGACATATTTATATGTA 8
210 mHC TATCTCTATGTAATAATCACTAAAAGTATCGAGTACATAGCTCTGACATATTTATATGTA 8
211 mHC AATACACTACAGCTATATGTCCCTGTCTTCGAAGACAGGGACATATAGCTGTAGTGTATT 14
212 sHC AATACACTACAGCTATATGTCCCTGTCTTCGAAGACAGGGACATATAGCTGTAGTGTATT 14
表1.c5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
113 10049364 10049395 10125282 10125313 16 10045394 10049395 10121312 10125313
114 10049364 10049395 10125282 10125313 16 10045394 10049395 10121312 10125313
115 46459835 46459866 46481483 46481514 19 46459835 46463836 46477513 46481514
116 46459835 46459866 46481483 46481514 19 46459835 46463836 46477513 46481514
117 41872387 41872418 41926859 41926890 21 41872387 41876388 41926859 41930860
118 41872387 41872418 41926859 41926890 21 41872387 41876388 41926859 41930860
119 16923015 16923046 16987493 16987524 22 16919045 16923046 16987493 16991494
120 16923015 16923046 16987493 16987524 22 16919045 16923046 16987493 16991494
121 65738736 65738767 65758131 65758162 3 65738736 65742737 65758131 65762132
122 65738736 65738767 65758131 65758162 3 65738736 65742737 65758131 65762132
123 65738736 65738767 65827279 65827310 3 65738736 65742737 65827279 65831280
124 65738736 65738767 65827279 65827310 3 65738736 65742737 65827279 65831280
125 79415953 79415984 79448857 79448888 7 79411983 79415984 79444887 79448888
126 79415953 79415984 79448857 79448888 7 79411983 79415984 79444887 79448888
127 10137237 10137268 10247633 10247664 8 10137237 10141238 10247633 10251634
128 10137237 10137268 10247633 10247664 8 10137237 10141238 10247633 10251634
129 16444934 16444965 16496760 16496791 3 16440964 16444965 16496760 16500761
130 16444934 16444965 16496760 16496791 3 16440964 16444965 16496760 16500761
131 36628023 36628054 36670823 36670854 13 36624053 36628054 36670823 36674824
132 36628023 36628054 36670823 36670854 13 36624053 36628054 36670823 36674824
133 38848295 38848326 38907082 38907113 X 38848295 38852296 38907082 38911083
134 38848295 38848326 38907082 38907113 X 38848295 38852296 38907082 38911083
135 68259991 68260022 68327682 68327713 14 68256021 68260022 68323712 68327713
136 68259991 68260022 68327682 68327713 14 68256021 68260022 68323712 68327713
137 127390647 127390678 127434266 127434297 5 127386677 127390678 127434266 127438267
138 127390647 127390678 127434266 127434297 5 127386677 127390678 127434266 127438267
139 30984126 30984157 31002238 31002269 21 30984126 30988127 30998268 31002269
140 30984126 30984157 31002238 31002269 21 30984126 30988127 30998268 31002269
141 78345645 78345676 78400290 78400321 14 78345645 78349646 78396320 78400321
142 78345645 78345676 78400290 78400321 14 78345645 78349646 78396320 78400321
143 84755923 84755954 84775145 84775176 6 84751953 84755954 84775145 84779146
144 84755923 84755954 84775145 84775176 6 84751953 84755954 84775145 84779146
145 3431982 3432013 3464169 3464200 8 3431982 3435983 3460199 3464200
146 3431982 3432013 3464169 3464200 8 3431982 3435983 3460199 3464200
147 33595213 33595244 33615647 33615678 11 33591243 33595244 33611677 33615678
148 33595213 33595244 33615647 33615678 11 33591243 33595244 33611677 33615678
149 23139410 23139441 23210381 23210412 16 23139410 23143411 23210381 23214382
150 23139410 23139441 23210381 23210412 16 23139410 23143411 23210381 23214382
151 65839372 65839403 65856122 65856153 3 65835402 65839403 65852152 65856153
152 65839372 65839403 65856122 65856153 3 65835402 65839403 65852152 65856153
153 84068704 84068735 84120868 84120899 11 84064734 84068735 84120868 84124869
154 84068704 84068735 84120868 84120899 11 84064734 84068735 84120868 84124869
155 38155445 38155476 38206549 38206580 2 38151475 38155476 38206549 38210550
156 38155445 38155476 38206549 38206580 2 38151475 38155476 38206549 38210550
157 43868341 43868372 43889253 43889284 3 43868341 43872342 43889253 43893254
158 43868341 43868372 43889253 43889284 3 43868341 43872342 43889253 43893254
159 103111808 103111839 103158499 103158530 X 103107838 103111839 103154529 103158530
160 103111808 103111839 103158499 103158530 X 103107838 103111839 103154529 103158530
161 36409666 36409697 36433268 36433299 1 36409666 36413667 36433268 36437269
162 36409666 36409697 36433268 36433299 1 36409666 36413667 36433268 36437269
163 49148928 49148959 49204579 49204610 11 49144958 49148959 49200609 49204610
164 49148928 49148959 49204579 49204610 11 49144958 49148959 49200609 49204610
165 13672704 13672735 13742062 13742093 12 13672704 13676705 13738092 13742093
166 13672704 13672735 13742062 13742093 12 13672704 13676705 13738092 13742093
167 169021738 169021769 169079530 169079561 2 169017768 169021769 169079530 169083531
168 169021738 169021769 169079530 169079561 2 169017768 169021769 169079530 169083531
169 20283807 20283838 20304911 20304942 2 20283807 20287808 20300941 20304942
170 20283807 20283838 20304911 20304942 2 20283807 20287808 20300941 20304942
171 20304911 20304942 20381252 20381283 2 20300941 20304942 20377282 20381283
172 20304911 20304942 20381252 20381283 2 20300941 20304942 20377282 20381283
173 84755923 84755954 84775145 84775176 6 84751953 84755954 84775145 84779146
174 84755923 84755954 84775145 84775176 6 84751953 84755954 84775145 84779146
175 52233796 52233827 52253135 52253166 8 52229826 52233827 52249165 52253166
176 52233796 52233827 52253135 52253166 8 52229826 52233827 52249165 52253166
177 65562483 65562514 65658401 65658432 8 65558513 65562514 65658401 65662402
178 65562483 65562514 65658401 65658432 8 65558513 65562514 65658401 65662402
179 38648333 38648364 38686830 38686861 9 38648333 38652334 38682860 38686861
180 38648333 38648364 38686830 38686861 9 38648333 38652334 38682860 38686861
181 28717278 28717309 28731416 28731447 7 28717278 28721279 28731416 28735417
182 28717278 28717309 28731416 28731447 7 28717278 28721279 28731416 28735417
183 36976432 36976463 37039732 37039763 7 36976432 36980433 37039732 37043733
184 36976432 36976463 37039732 37039763 7 36976432 36980433 37039732 37043733
185 77514867 77514898 77580704 77580735 2 77514867 77518868 77576734 77580735
186 77514867 77514898 77580704 77580735 2 77514867 77518868 77576734 77580735
187 55502863 55502894 55533743 55533774 1 55502863 55506864 55533743 55537744
188 55502863 55502894 55533743 55533774 1 55502863 55506864 55533743 55537744
189 195535991 195536022 195589030 195589061 2 195535991 195539992 195585060 195589061
190 195535991 195536022 195589030 195589061 2 195535991 195539992 195585060 195589061
191 33273553 33273584 33317596 33317627 9 33273553 33277554 33317596 33321597
192 33273553 33273584 33317596 33317627 9 33273553 33277554 33317596 33321597
193 42093750 42093781 42144509 42144540 2 42093750 42097751 42140539 42144540
194 42093750 42093781 42144509 42144540 2 42093750 42097751 42140539 42144540
195 45370280 45370311 45421686 45421717 7 45366310 45370311 45421686 45425687
196 45370280 45370311 45421686 45421717 7 45366310 45370311 45421686 45425687
197 96311004 96311035 96328347 96328378 15 96307034 96311035 96328347 96332348
198 96311004 96311035 96328347 96328378 15 96307034 96311035 96328347 96332348
199 22663253 22663284 22709447 22709478 10 22659283 22663284 22705477 22709478
200 22663253 22663284 22709447 22709478 10 22659283 22663284 22705477 22709478
201 198074515 198074546 198099686 198099717 2 198070545 198074546 198099686 198103687
202 198074515 198074546 198099686 198099717 2 198070545 198074546 198099686 198103687
203 76403646 76403677 76480867 76480898 10 76403646 76407647 76480867 76484868
204 76403646 76403677 76480867 76480898 10 76403646 76407647 76480867 76484868
205 66539108 66539139 66592400 66592431 2 66539108 66543109 66592400 66596401
206 66539108 66539139 66592400 66592431 2 66539108 66543109 66592400 66596401
207 10103712 10103743 10175240 10175271 8 10099742 10103743 10171270 10175271
208 10103712 10103743 10175240 10175271 8 10099742 10103743 10171270 10175271
209 65562483 65562514 65637133 65637164 8 65558513 65562514 65637133 65641134
210 65562483 65562514 65637133 65637164 8 65558513 65562514 65637133 65641134
211 106698878 106698909 106745349 106745380 14 106694908 106698909 106741379 106745380
212 106698878 106698909 106745349 106745380 14 106694908 106698909 106741379 106745380
表1.c6
   探針 PCR- 引子 1_ID PCR_ 引子 1
113 ORF13_16_10047306_10049395_10119747_10125313_FF OBD159_225 CTCAAGTTGTCACAGCATTACCACCT
114 ORF13_16_10047306_10049395_10119747_10125313_FF OBD159_225 CTCAAGTTGTCACAGCATTACCACCT
115 ORF13_19_46459835_46460902_46479838_46481514_RF OBD159_229 CAGTCTTGGCTGGTGATGATTCCTGA
116 ORF13_19_46459835_46460902_46479838_46481514_RF OBD159_229 CAGTCTTGGCTGGTGATGATTCCTGA
117 ORF13_21_41872387_41876215_41926859_41930173_RR OBD159_233 CCTCCTGAACCACCACCTCTGGC
118 ORF13_21_41872387_41876215_41926859_41930173_RR OBD159_233 CCTCCTGAACCACCACCTCTGGC
119 ORF13_22_16921135_16923046_16987493_16991720_FR OBD159_237 CAAGTAATCATTTCTCTTCATTTTG
120 ORF13_22_16921135_16923046_16987493_16991720_FR OBD159_237 CAAGTAATCATTTCTCTTCATTTTG
121 ORF13_3_65738736_65743505_65758131_65766427_RR OBD159_241 AAGCCCTTGTTGAGACCTACTTCCTC
122 ORF13_3_65738736_65743505_65758131_65766427_RR OBD159_241 AAGCCCTTGTTGAGACCTACTTCCTC
123 ORF13_3_65738736_65743505_65827279_65831993_RR OBD159_245 AAGCCCTTGTTGAGACCTACTTCCTC
124 ORF13_3_65738736_65743505_65827279_65831993_RR OBD159_245 AAGCCCTTGTTGAGACCTACTTCCTC
125 ORF13_7_79409384_79415984_79434265_79448888_FF OBD159_249 TAAACTTGCTGGTCTCTTCCACAGTA
126 ORF13_7_79409384_79415984_79434265_79448888_FF OBD159_249 TAAACTTGCTGGTCTCTTCCACAGTA
127 ORF13_8_10137237_10138418_10247633_10250634_RR OBD159_253 GGCAGCCTACTTTGCTTGCTCTCAA
128 ORF13_8_10137237_10138418_10247633_10250634_RR OBD159_253 GGCAGCCTACTTTGCTTGCTCTCAA
129 ORF130_3_16438382_16444965_16496760_16499694_FR OBD159_257 CCACTACAACCACCATCACTCGC
130 ORF130_3_16438382_16444965_16496760_16499694_FR OBD159_257 CCACTACAACCACCATCACTCGC
131 ORF131_13_36625595_36628054_36670823_36673255_FR OBD159_261 GGTAGTCTCTGAGGTGTCATTCT
132 ORF131_13_36625595_36628054_36670823_36673255_FR OBD159_261 GGTAGTCTCTGAGGTGTCATTCT
133 ORF132_X_38848295_38850360_38907082_38913455_RR OBD159_265 GCCAACACATCAGGAGTGGGAAG
134 ORF132_X_38848295_38850360_38907082_38913455_RR OBD159_265 GCCAACACATCAGGAGTGGGAAG
135 ORF133_14_68255587_68260022_68325745_68327713_FF OBD159_269 GTGTTGGGCATTGAGAAAGTGGTGAA
136 ORF133_14_68255587_68260022_68325745_68327713_FF OBD159_269 GTGTTGGGCATTGAGAAAGTGGTGAA
137 ORF133_5_127388766_127390678_127434266_127436041_FR OBD159_273 CTCCTGACCTCAAATGATACTCTTGT
138 ORF133_5_127388766_127390678_127434266_127436041_FR OBD159_273 CTCCTGACCTCAAATGATACTCTTGT
139 ORF134_21_30984126_30988102_30998437_31002269_RF OBD159_277 TAACCAGGGTAGCCTTGATGCCAGC
140 ORF134_21_30984126_30988102_30998437_31002269_RF OBD159_277 TAACCAGGGTAGCCTTGATGCCAGC
141 ORF135_14_78345645_78349226_78398012_78400321_RF OBD159_281 GCCAAGAAGTAGTAGTTATTCCCTCC
142 ORF135_14_78345645_78349226_78398012_78400321_RF OBD159_281 GCCAAGAAGTAGTAGTTATTCCCTCC
143 ORF135_6_84752549_84755954_84775145_84786636_FR OBD159_285 AAGACATTGTTTAGCAACTTCCAA
144 ORF135_6_84752549_84755954_84775145_84786636_FR OBD159_285 AAGACATTGTTTAGCAACTTCCAA
145 ORF135_8_3431982_3435558_3460548_3464200_RF OBD159_289 CAGCAGCACATCACAGGAAACAGTTC
146 ORF135_8_3431982_3435558_3460548_3464200_RF OBD159_289 CAGCAGCACATCACAGGAAACAGTTC
147 ORF136_11_33584612_33595244_33612657_33615678_FF OBD159_293 GAATAAGCACTTCTTCTTGGATTAGC
148 ORF136_11_33584612_33595244_33612657_33615678_FF OBD159_293 GAATAAGCACTTCTTCTTGGATTAGC
149 ORF136_16_23139410_23143862_23210381_23212701_RR OBD159_297 GCAGGAAAACCAGGAAGGCAGAG
150 ORF136_16_23139410_23143862_23210381_23212701_RR OBD159_297 GCAGGAAAACCAGGAAGGCAGAG
151 ORF136_3_65835051_65839403_65852931_65856153_FF OBD159_301 ACCTACTGTGCTGCCAGACATAGAAA
152 ORF136_3_65835051_65839403_65852931_65856153_FF OBD159_301 ACCTACTGTGCTGCCAGACATAGAAA
153 ORF138_11_84067130_84068735_84120868_84126600_FR OBD159_305 CCAGTTATTTGCTCCAGTGTTCCTCC
154 ORF138_11_84067130_84068735_84120868_84126600_FR OBD159_305 CCAGTTATTTGCTCCAGTGTTCCTCC
155 ORF139_2_38148629_38155476_38206549_38210637_FR OBD159_309 CCCGCCCACATCCTGAGAATCCTTTT
156 ORF139_2_38148629_38155476_38206549_38210637_FR OBD159_309 CCCGCCCACATCCTGAGAATCCTTTT
157 ORF139_3_43868341_43870688_43889253_43893962_RR OBD159_313 CTCTTCTGACCCTTTGCCCTTCCCAT
158 ORF139_3_43868341_43870688_43889253_43893962_RR OBD159_313 CTCTTCTGACCCTTTGCCCTTCCCAT
159 ORF139_X_103107164_103111839_103149176_103158530_FF OBD159_317 GGGATGCCTGGGACATAAGTCAGATG
160 ORF139_X_103107164_103111839_103149176_103158530_FF OBD159_317 GGGATGCCTGGGACATAAGTCAGATG
161 ORF14_1_36409666_36411937_36433268_36434547_RR OBD159_165 GAAGCGAGTTGCTGTCACTGGAG
162 ORF14_1_36409666_36411937_36433268_36434547_RR OBD159_165 GAAGCGAGTTGCTGTCACTGGAG
163 ORF14_11_49143461_49148959_49200052_49204610_FF OBD159_321 GTTTCAGGACCACCCTCTACACC
164 ORF14_11_49143461_49148959_49200052_49204610_FF OBD159_321 GTTTCAGGACCACCCTCTACACC
165 ORF14_12_13672704_13680228_13739178_13742093_RF OBD159_325 AGCCCTTGGCACATAGTATTCACTCA
166 ORF14_12_13672704_13680228_13739178_13742093_RF OBD159_325 AGCCCTTGGCACATAGTATTCACTCA
167 ORF14_2_169020149_169021769_169079530_169081990_FR OBD159_329 CAACCTAACACAACATAGCCTGC
168 ORF14_2_169020149_169021769_169079530_169081990_FR OBD159_329 CAACCTAACACAACATAGCCTGC
169 ORF14_2_20283807_20286153_20303337_20304942_RF OBD159_333 CATTTGTCAACTCACACTCTAAAA
170 ORF14_2_20283807_20286153_20303337_20304942_RF OBD159_333 CATTTGTCAACTCACACTCTAAAA
171 ORF14_2_20303337_20304942_20379482_20381283_FF OBD159_337 ACATTTGTCAACTCACACTCTAAA
172 ORF14_2_20303337_20304942_20379482_20381283_FF OBD159_337 ACATTTGTCAACTCACACTCTAAA
173 ORF14_6_84752549_84755954_84775145_84786636_FR OBD159_285 AAGACATTGTTTAGCAACTTCCAA
174 ORF14_6_84752549_84755954_84775145_84786636_FR OBD159_285 AAGACATTGTTTAGCAACTTCCAA
175 ORF14_8_52230322_52233827_52248401_52253166_FF OBD159_341 TATTATTTTCATTGGCTTTCACCAG
176 ORF14_8_52230322_52233827_52248401_52253166_FF OBD159_341 TATTATTTTCATTGGCTTTCACCAG
177 ORF14_8_65560550_65562514_65658401_65661888_FR OBD159_345 CCTTGATAGAGAAAACAAAATGCTT
178 ORF14_8_65560550_65562514_65658401_65661888_FR OBD159_345 CCTTGATAGAGAAAACAAAATGCTT
179 ORF14_9_38648333_38653476_38681931_38686861_RF OBD159_349 CAGAAGTTCACAGGCAGGGTGTC
180 ORF14_9_38648333_38653476_38681931_38686861_RF OBD159_349 CAGAAGTTCACAGGCAGGGTGTC
181 ORF140_7_28717278_28719857_28731416_28736388_RR OBD159_353 CCCCAGAGTTCCTTTGGCTCCCA
182 ORF140_7_28717278_28719857_28731416_28736388_RR OBD159_353 CCCCAGAGTTCCTTTGGCTCCCA
183 ORF140_7_36976432_36980351_37039732_37049390_RR OBD159_357 CAATGGGATACTTCTCTTGGGTTTGG
184 ORF140_7_36976432_36980351_37039732_37049390_RR OBD159_357 CAATGGGATACTTCTCTTGGGTTTGG
185 ORF141_2_77514867_77519288_77576705_77580735_RF OBD159_361 GGTGATGGGACTAAGCCTCAGGTTTT
186 ORF141_2_77514867_77519288_77576705_77580735_RF OBD159_361 GGTGATGGGACTAAGCCTCAGGTTTT
187 ORF142_1_55502863_55511336_55533743_55538240_RR OBD159_365 CCAGAGAGCCAGTGCTTTCAACTCCA
188 ORF142_1_55502863_55511336_55533743_55538240_RR OBD159_365 CCAGAGAGCCAGTGCTTTCAACTCCA
189 ORF142_2_195535991_195542111_195583610_195589061_RF OBD159_369 CAGGCTATTGGAATGGCTGAAGTGTG
190 ORF142_2_195535991_195542111_195583610_195589061_RF OBD159_369 CAGGCTATTGGAATGGCTGAAGTGTG
191 ORF144_9_33273553_33275175_33317596_33319558_RR OBD159_373 CCTACACACACACAACAGCAAAATAA
192 ORF144_9_33273553_33275175_33317596_33319558_RR OBD159_373 CCTACACACACACAACAGCAAAATAA
193 ORF145_2_42093750_42101196_42140119_42144540_RF OBD159_377 AGGGAAGAAGGCTGCTATGTATTGGG
194 ORF145_2_42093750_42101196_42140119_42144540_RF OBD159_377 AGGGAAGAAGGCTGCTATGTATTGGG
195 ORF145_7_45364155_45370311_45421686_45426816_FR OBD159_381 TTTAGCAGTGAAGTCATCAGGTCCT
196 ORF145_7_45364155_45370311_45421686_45426816_FR OBD159_381 TTTAGCAGTGAAGTCATCAGGTCCT
197 ORF147_15_96308452_96311035_96328347_96331473_FR OBD159_385 TCAAAATGATAGGTTCACAGTTCGTG
198 ORF147_15_96308452_96311035_96328347_96331473_FR OBD159_385 TCAAAATGATAGGTTCACAGTTCGTG
199 ORF148_10_22661441_22663284_22705207_22709478_FF OBD159_389 CACATTCTTTTGGGCTCTGCCACTCC
200 ORF148_10_22661441_22663284_22705207_22709478_FF OBD159_389 CACATTCTTTTGGGCTCTGCCACTCC
201 ORF148_2_198067347_198074546_198099686_198102962_FR OBD159_393 GGACTCCAAAGTGACTAAAATCAATG
202 ORF148_2_198067347_198074546_198099686_198102962_FR OBD159_393 GGACTCCAAAGTGACTAAAATCAATG
203 ORF15_10_76403646_76410014_76480867_76489182_RR OBD159_397 AGAACCCTGGTCCCACCCCTTTA
204 ORF15_10_76403646_76410014_76480867_76489182_RR OBD159_397 AGAACCCTGGTCCCACCCCTTTA
205 ORF15_2_66539108_66541258_66592400_66595314_RR OBD159_401 GTAATACCAGCACTTTAGGAGGC
206 ORF15_2_66539108_66541258_66592400_66595314_RR OBD159_401 GTAATACCAGCACTTTAGGAGGC
207 ORF15_8_10100695_10103743_10173552_10175271_FF OBD159_405 AGTGAGATAATGTGCCTGAAAGCAAT
208 ORF15_8_10100695_10103743_10173552_10175271_FF OBD159_405 AGTGAGATAATGTGCCTGAAAGCAAT
209 ORF15_8_65560550_65562514_65637133_65640837_FR OBD159_409 ACCTTGATAGAGAAAACAAAATGCT
210 ORF15_8_65560550_65562514_65637133_65640837_FR OBD159_409 ACCTTGATAGAGAAAACAAAATGCT
211 ORF151_14_106693397_106698909_106739902_106745380_FF OBD159_413 CGCAACGGGTCCCAGCATCATCT
212 ORF151_14_106693397_106698909_106739902_106745380_FF OBD159_413 CGCAACGGGTCCCAGCATCATCT
表1.c7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
113 OBD159_227 CTTGACCTCTTGACGCCTTCTACTTC OBD159_225_227 -0.003478138
114 OBD159_227 CTTGACCTCTTGACGCCTTCTACTTC OBD159_225_227 -0.003478138
115 OBD159_231 CCCTTCAGTGGAACCTTACCCAACAA OBD159_229_231 -0.002532463
116 OBD159_231 CCCTTCAGTGGAACCTTACCCAACAA OBD159_229_231 -0.002532463
117 OBD159_235 GGAGTTCTTTCCTTGGGTGTTACAG OBD159_233_235 -0.001863826
118 OBD159_235 GGAGTTCTTTCCTTGGGTGTTACAG OBD159_233_235 -0.001863826
119 OBD159_239 GATTCCTAAGAAACCTACCATTAT OBD159_237_239 -0.001138844
120 OBD159_239 GATTCCTAAGAAACCTACCATTAT OBD159_237_239 -0.001138844
121 OBD159_243 TGTGGAAAGGTGATTGGCTCAACAGC OBD159_241_243 -0.00258233
122 OBD159_243 TGTGGAAAGGTGATTGGCTCAACAGC OBD159_241_243 -0.00258233
123 OBD159_247 GAGCAAGAGCAGTTTGGCTGTGTTGT OBD159_245_247 -0.00500142
124 OBD159_247 GAGCAAGAGCAGTTTGGCTGTGTTGT OBD159_245_247 -0.00500142
125 OBD159_251 CATTGCTCTACCCCACCTTCTGAGGA OBD159_249_251 -0.000699189
126 OBD159_251 CATTGCTCTACCCCACCTTCTGAGGA OBD159_249_251 -0.000699189
127 OBD159_255 CTCTCCTTCTGTGTATGGGTAAGACC OBD159_253_255 -0.004180686
128 OBD159_255 CTCTCCTTCTGTGTATGGGTAAGACC OBD159_253_255 -0.004180686
129 OBD159_259 GTTTGGGCGGTTTCCAGGATGGG OBD159_257_259 -0.003029176
130 OBD159_259 GTTTGGGCGGTTTCCAGGATGGG OBD159_257_259 -0.003029176
131 OBD159_263 CTACTAAGTGGCTAATGGGTGGG OBD159_261_263 -0.003552931
132 OBD159_263 CTACTAAGTGGCTAATGGGTGGG OBD159_261_263 -0.003552931
133 OBD159_267 GCTTCCCTCCTCTGTAGCCAATAGC OBD159_265_267 -0.001420022
134 OBD159_267 GCTTCCCTCCTCTGTAGCCAATAGC OBD159_265_267 -0.001420022
135 OBD159_271 GCCAAAGACTCCTCTGGGAATCCAAC OBD159_269_271 -0.003881009
136 OBD159_271 GCCAAAGACTCCTCTGGGAATCCAAC OBD159_269_271 -0.003881009
137 OBD159_275 TCTTGGCATAAAGCAGGGCTCCAGGA OBD159_273_275 -0.000941074
138 OBD159_275 TCTTGGCATAAAGCAGGGCTCCAGGA OBD159_273_275 -0.000941074
139 OBD159_279 TTGTCAGTGTTACAGGATTAGACTCC OBD159_277_279 -0.002446219
140 OBD159_279 TTGTCAGTGTTACAGGATTAGACTCC OBD159_277_279 -0.002446219
141 OBD159_283 CCTCAACATCCCAAAACGGGTTCCTC OBD159_281_283 -0.003527946
142 OBD159_283 CCTCAACATCCCAAAACGGGTTCCTC OBD159_281_283 -0.003527946
143 OBD159_287 TTTGTAAACGGTTGGGAGACTTAG OBD159_285_287 -0.002652581
144 OBD159_287 TTTGTAAACGGTTGGGAGACTTAG OBD159_285_287 -0.002652581
145 OBD159_291 AACTGGGTTCTGGGACTTTTCCTCAG OBD159_289_291 -0.003934436
146 OBD159_291 AACTGGGTTCTGGGACTTTTCCTCAG OBD159_289_291 -0.003934436
147 OBD159_295 GGGATGTTGCCTCCGAGACAAAA OBD159_293_295 -0.005396785
148 OBD159_295 GGGATGTTGCCTCCGAGACAAAA OBD159_293_295 -0.005396785
149 OBD159_299 GGGAGCCAGAGAACACCTGCTTC OBD159_297_299 -0.000755854
150 OBD159_299 GGGAGCCAGAGAACACCTGCTTC OBD159_297_299 -0.000755854
151 OBD159_303 GAGGGACTGGGTGGGAGGAGTATTTT OBD159_301_303 -0.000778321
152 OBD159_303 GAGGGACTGGGTGGGAGGAGTATTTT OBD159_301_303 -0.000778321
153 OBD159_307 CTCCAACTGACCACTAAAACCACATA OBD159_305_307 -0.001663304
154 OBD159_307 CTCCAACTGACCACTAAAACCACATA OBD159_305_307 -0.001663304
155 OBD159_311 AGTTCCACTTCCCCATACTCACAAAC OBD159_309_311 -0.001494243
156 OBD159_311 AGTTCCACTTCCCCATACTCACAAAC OBD159_309_311 -0.001494243
157 OBD159_315 GGGCTAAAGTGGGTAAAGTCTCAAAA OBD159_313_315 -0.001782575
158 OBD159_315 GGGCTAAAGTGGGTAAAGTCTCAAAA OBD159_313_315 -0.001782575
159 OBD159_319 GACACTCACACACAGAAATACTGCCA OBD159_317_319 -0.002307627
160 OBD159_319 GACACTCACACACAGAAATACTGCCA OBD159_317_319 -0.002307627
161 OBD159_167 CCCCAACACAAACTGTCCTCAGGC OBD159_165_167 -0.005406694
162 OBD159_167 CCCCAACACAAACTGTCCTCAGGC OBD159_165_167 -0.005406694
163 OBD159_323 GACCATACCTTGCCAGACCTCCAC OBD159_321_323 -0.000820401
164 OBD159_323 GACCATACCTTGCCAGACCTCCAC OBD159_321_323 -0.000820401
165 OBD159_327 TATGTTGTTGCCCTTGATACGGTAGC OBD159_325_327 -0.003236838
166 OBD159_327 TATGTTGTTGCCCTTGATACGGTAGC OBD159_325_327 -0.003236838
167 OBD159_331 GGATTACAGGCGTGAGCCACCAC OBD159_329_331 -0.001954353
168 OBD159_331 GGATTACAGGCGTGAGCCACCAC OBD159_329_331 -0.001954353
169 OBD159_335 ATGAGGCACTTGATTTTGAACTTC OBD159_333_335 -0.003110365
170 OBD159_335 ATGAGGCACTTGATTTTGAACTTC OBD159_333_335 -0.003110365
171 OBD159_339 TATCCAGTCTCCCAACATCATTTGT OBD159_337_339 -0.002009345
172 OBD159_339 TATCCAGTCTCCCAACATCATTTGT OBD159_337_339 -0.002009345
173 OBD159_287 TTTGTAAACGGTTGGGAGACTTAG OBD159_285_287 -0.00372894
174 OBD159_287 TTTGTAAACGGTTGGGAGACTTAG OBD159_285_287 -0.00372894
175 OBD159_343 TATTTCCCTAACATAACGATAGTGC OBD159_341_343 -0.002079504
176 OBD159_343 TATTTCCCTAACATAACGATAGTGC OBD159_341_343 -0.002079504
177 OBD159_347 GTAGAAGAGAAACCCAGATAAATA OBD159_345_347 -0.001315086
178 OBD159_347 GTAGAAGAGAAACCCAGATAAATA OBD159_345_347 -0.001315086
179 OBD159_351 GACCACAGGCACCACCATACCCT OBD159_349_351 -0.002703631
180 OBD159_351 GACCACAGGCACCACCATACCCT OBD159_349_351 -0.002703631
181 OBD159_355 CCCGAACTCCCTTCCTGTTTTGG OBD159_353_355 -0.001783895
182 OBD159_355 CCCGAACTCCCTTCCTGTTTTGG OBD159_353_355 -0.001783895
183 OBD159_359 ACAGGAAAGCCTACTGGACAACATTG OBD159_357_359 -0.002901823
184 OBD159_359 ACAGGAAAGCCTACTGGACAACATTG OBD159_357_359 -0.002901823
185 OBD159_363 AGTGTGCTTGGTTGAACTGAATCATT OBD159_361_363 -0.002666837
186 OBD159_363 AGTGTGCTTGGTTGAACTGAATCATT OBD159_361_363 -0.002666837
187 OBD159_367 GGCAACTAACACTTGTCTCACCTTCA OBD159_365_367 -0.002519385
188 OBD159_367 GGCAACTAACACTTGTCTCACCTTCA OBD159_365_367 -0.002519385
189 OBD159_371 CCTGCTCTGCCACTAACCAAGTATGT OBD159_369_371 -0.003311287
190 OBD159_371 CCTGCTCTGCCACTAACCAAGTATGT OBD159_369_371 -0.003311287
191 OBD159_375 GGACTACAGGCGTGAGCCACCAC OBD159_373_375 -0.002586717
192 OBD159_375 GGACTACAGGCGTGAGCCACCAC OBD159_373_375 -0.002586717
193 OBD159_379 ATCCATCCTTCTCACAGCAGCCAAGA OBD159_377_379 -0.000261394
194 OBD159_379 ATCCATCCTTCTCACAGCAGCCAAGA OBD159_377_379 -0.000261394
195 OBD159_383 ATTGAATAGCCATCAGCAAGAAAA OBD159_381_383 -0.003357596
196 OBD159_383 ATTGAATAGCCATCAGCAAGAAAA OBD159_381_383 -0.003357596
197 OBD159_387 TGAGACTTCCATAGCAGATTACCTTT OBD159_385_387 -0.004574718
198 OBD159_387 TGAGACTTCCATAGCAGATTACCTTT OBD159_385_387 -0.004574718
199 OBD159_391 GAACCTCATCTGTCTAACCACAAACC OBD159_389_391 -0.002633812
200 OBD159_391 GAACCTCATCTGTCTAACCACAAACC OBD159_389_391 -0.002633812
201 OBD159_395 TAGTTCAAGTTCTTCTCAAAAGCCCC OBD159_393_395 -0.003551604
202 OBD159_395 TAGTTCAAGTTCTTCTCAAAAGCCCC OBD159_393_395 -0.003551604
203 OBD159_399 GAGTCGCTGTCCCAATGGCAGGA OBD159_397_399 -0.004114077
204 OBD159_399 GAGTCGCTGTCCCAATGGCAGGA OBD159_397_399 -0.004114077
205 OBD159_403 CCATTTTACAGGTGAACAAACTGATG OBD159_401_403 -0.004584406
206 OBD159_403 CCATTTTACAGGTGAACAAACTGATG OBD159_401_403 -0.004584406
207 OBD159_407 TAGCCCCTTTCCCACAACTTTTCTGC OBD159_405_407 -0.002097489
208 OBD159_407 TAGCCCCTTTCCCACAACTTTTCTGC OBD159_405_407 -0.002097489
209 OBD159_411 GTTCAAGGTTTCCCTCTGCTTCTA OBD159_409_411 -0.001313422
210 OBD159_411 GTTCAAGGTTTCCCTCTGCTTCTA OBD159_409_411 -0.001313422
211 OBD159_415 CTTGCCTTACCACCTGCTCTTCC OBD159_413_415 -0.003147124
212 OBD159_415 CTTGCCTTACCACCTGCTCTTCC OBD159_413_415 -0.003147124
表1.c8
   基因
113 GRIN2A; rs7192557
114 GRIN2A; rs7192557
115 PNMAL1; PNMAL2; PPP5D1
116 PNMAL1; PNMAL2; PPP5D1
117 C2CD2; PRDM15; ZBTB21; rs451390
118 C2CD2; PRDM15; ZBTB21; rs451390
119 GAB4; rs41433045
120 GAB4; rs41433045
121 MAGI1; rs11924265
122 MAGI1; rs11924265
123 MAGI1; rs7633294; rs11924265; rs1909492; rs145965284
124 MAGI1; rs7633294; rs11924265; rs1909492; rs145965284
125 MAGI2; rs1135402912
126 MAGI2; rs1135402912
127 MSRA; rs7001567; rs10107815; rs73191547; rs17749155; rs2975735
128 MSRA; rs7001567; rs10107815; rs73191547; rs17749155; rs2975735
129 RFTN1; rs3856834
130 RFTN1; rs3856834
131 SERTM1; rs11619726
132 SERTM1; rs11619726
133 MID1IP1; rs199860
134 MID1IP1; rs199860
135 RAD51B; rs1570106; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566
136 RAD51B; rs1570106; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566
137 MEGF10; rs387907071; rs143954261; rs387907073; rs794726679; rs1057518682; rs794726677
138 MEGF10; rs387907071; rs143954261; rs387907073; rs794726679; rs1057518682; rs794726677
139 KRTAP19-8; rs8134605
140 KRTAP19-8; rs8134605
141 NRXN3; rs11624704
142 NRXN3; rs11624704
143 TBX18; rs869320679; rs797045022; rs77693245
144 TBX18; rs869320679; rs797045022; rs77693245
145 CSMD1; rs2938236; rs17066135
146 CSMD1; rs2938236; rs17066135
147 KIAA1549L; rs4755718; rs2076625
148 KIAA1549L; rs4755718; rs2076625
149 SCNN1G; USP31; rs137853342; rs5736
150 SCNN1G; USP31; rs137853342; rs5736
151 MAGI1; rs145965284
152 MAGI1; rs145965284
153 DLG2; rs790356
154 DLG2; rs790356
155 ATL2; CYP1B1
156 ATL2; CYP1B1
157 rs6441806; rs75594032
158 rs6441806; rs75594032
159 BEX4; NXF3
160 BEX4; NXF3
161 LSM10; OSCP1
162 LSM10; OSCP1
163 FOLH1; rs202676; rs368939818; rs61886492; rs770894245; rs747052707; rs202680
164 FOLH1; rs202676; rs368939818; rs61886492; rs770894245; rs747052707; rs202680
165 GRIN2B; rs1060499526; rs2192970; rs2284411; rs2268118
166 GRIN2B; rs1060499526; rs2192970; rs2284411; rs2268118
167 ABCB11; DHRS9; rs886043986; rs2161037
168 ABCB11; DHRS9; rs886043986; rs2161037
169 PUM2; rs111612372
170 PUM2; rs111612372
171 PUM2; rs585017
172 PUM2; rs585017
173 TBX18; rs869320679; rs797045022; rs77693245
174 TBX18; rs869320679; rs797045022; rs77693245
175 ST18; rs2360806
176 ST18; rs2360806
177 ARMC1; MTFR1; rs6991838
178 ARMC1; MTFR1; rs6991838
179 ANKRD18A; CNTNAP3
180 ANKRD18A; CNTNAP3
181 CREB5; rs56388170
182 CREB5; rs56388170
183 ELMO1; rs6942726; rs17170851
184 ELMO1; rs6942726; rs17170851
185 LRRTM4; rs61354037
186 LRRTM4; rs61354037
187 rs1998013; rs10888935
188 rs1998013; rs10888935
189 DNAH7; SLC39A10
190 DNAH7; SLC39A10
191 BAG1; CHMP5; NFX1
192 BAG1; CHMP5; NFX1
193 EML4; rs17029233
194 EML4; rs17029233
195 ADCY1; rs1294908
196 ADCY1; rs1294908
197 NR2F2; rs587777373; rs2398180
198 NR2F2; rs587777373; rs2398180
199 PIP4K2A; rs1409395; rs370356098
200 PIP4K2A; rs1409395; rs370356098
201 PLCL1; rs7587251; rs6745726; rs1368989; rs12105927; rs7590828; rs1866666; rs1036333; rs2164068; rs1064213; rs11684176
202 PLCL1; rs7587251; rs6745726; rs1368989; rs12105927; rs7590828; rs1866666; rs1036333; rs2164068; rs1064213; rs11684176
203 C10orf11; rs10509373; rs11593840
204 C10orf11; rs10509373; rs11593840
205 MEIS1; rs10865355; rs11897119; rs2300478; rs2300481
206 MEIS1; rs10865355; rs11897119; rs2300478; rs2300481
207 MSRA; rs73191547; rs10087178; rs10107815
208 MSRA; rs73191547; rs10087178; rs10107815
209 ARMC1; rs6991838
210 ARMC1; rs6991838
211 rs2337406; rs11846409
212 rs2337406; rs11846409
表1.c9
   探針 基因座
213 ORF152_14_106693397_106698909_106739902_106745380_RR rs2337406; rs11846409
214 ORF152_14_106693397_106698909_106739902_106745380_RR rs2337406; rs11846409
215 ORF153_3_65835051_65839403_65898255_65903690_FF MAGI1; rs145965284
216 ORF153_3_65835051_65839403_65898255_65903690_FF MAGI1; rs145965284
217 ORF153_7_131130568_131132000_131219450_131221740_RR MKLN1; rs114034759
218 ORF153_7_131130568_131132000_131219450_131221740_RR MKLN1; rs114034759
219 ORF154_6_73688989_73690148_73751804_73758297_FF CD109; SLC17A5
220 ORF154_6_73688989_73690148_73751804_73758297_FF CD109; SLC17A5
221 ORF155_18_3106299_3108561_3129940_3131675_RR MYOM1; rs751200138
222 ORF155_18_3106299_3108561_3129940_3131675_RR MYOM1; rs751200138
223 ORF155_5_36136424_36142007_36160830_36164969_FF LMBRD2; SKP2; rs2270909; rs12657634; rs10941274; rs12655052; rs3804446
224 ORF155_5_36136424_36142007_36160830_36164969_FF LMBRD2; SKP2; rs2270909; rs12657634; rs10941274; rs12655052; rs3804446
225 ORF158_5_26999889_27004744_27042244_27044606_RF CDH9; rs201058683
226 ORF158_5_26999889_27004744_27042244_27044606_RF CDH9; rs201058683
227 ORF16_1_36409666_36411937_36433268_36434547_RR LSM10; OSCP1
228 ORF16_1_36409666_36411937_36433268_36434547_RR LSM10; OSCP1
229 ORF16_2_66446190_66449017_66470757_66475654_FR MEIS1; rs11692361
230 ORF16_2_66446190_66449017_66470757_66475654_FR MEIS1; rs11692361
231 ORF16_3_107626100_107637571_107708851_107713617_RR BBX; rs11710737
232 ORF16_3_107626100_107637571_107708851_107713617_RR BBX; rs11710737
233 ORF16_4_175829279_175833051_175892267_175894404_RR GPM6A; rs1106568
234 ORF16_4_175829279_175833051_175892267_175894404_RR GPM6A; rs1106568
235 ORF16_5_6223946_6226870_6283431_6289065_FR rs12518614
236 ORF16_5_6223946_6226870_6283431_6289065_FR rs12518614
237 ORF16_8_52380368_52388099_52462030_52466077_RR ST18; rs7820212
238 ORF16_8_52380368_52388099_52462030_52466077_RR ST18; rs7820212
239 ORF16_8_67971637_67976278_68010294_68014710_RR PREX2; rs4512367
240 ORF16_8_67971637_67976278_68010294_68014710_RR PREX2; rs4512367
241 ORF16_9_38681931_38686861_38768696_38769724_FR ANKRD18A; CNTNAP3
242 ORF16_9_38681931_38686861_38768696_38769724_FR ANKRD18A; CNTNAP3
243 ORF160_5_93562856_93565579_93582366_93583770_FF NR2F1; rs587777277
244 ORF160_5_93562856_93565579_93582366_93583770_FF NR2F1; rs587777277
245 ORF162_14_51804670_51807147_51886119_51892276_RF FRMD6; GNG2; rs8015138
246 ORF162_14_51804670_51807147_51886119_51892276_RF FRMD6; GNG2; rs8015138
247 ORF162_6_146094504_146104695_146155392_146161780_RR GRM1; SHPRH
248 ORF162_6_146094504_146104695_146155392_146161780_RR GRM1; SHPRH
249 ORF163_19_36775089_36776260_36803032_36806792_FR ZNF790; ZNF850
250 ORF163_19_36775089_36776260_36803032_36806792_FR ZNF790; ZNF850
251 ORF164_1_229859020_229862315_229908605_229911291_RF GALNT2; rs4925506
252 ORF164_1_229859020_229862315_229908605_229911291_RF GALNT2; rs4925506
253 ORF164_7_45364155_45370311_45384350_45391053_FF ADCY1; rs1294908
254 ORF164_7_45364155_45370311_45384350_45391053_FF ADCY1; rs1294908
255 ORF166_12_130196441_130198032_130248318_130252496_FF FZD10; PIWIL1
256 ORF166_12_130196441_130198032_130248318_130252496_FF FZD10; PIWIL1
257 ORF166_14_89880613_89884758_89952946_89954082_RR EFCAB11; TDP1
258 ORF166_14_89880613_89884758_89952946_89954082_RR EFCAB11; TDP1
259 ORF169_1_206307932_206310423_206383244_206385305_FF SRGAP2; rs2987927
260 ORF169_1_206307932_206310423_206383244_206385305_FF SRGAP2; rs2987927
261 ORF17_1_76086337_76098934_76123667_76127663_FF ST6GALNAC3; rs915404
262 ORF17_1_76086337_76098934_76123667_76127663_FF ST6GALNAC3; rs915404
263 ORF17_11_128975846_128978309_129021767_129026895_FR ARHGAP32; rs11221522
264 ORF17_11_128975846_128978309_129021767_129026895_FR ARHGAP32; rs11221522
265 ORF17_2_78763526_78765449_78792347_78798562_FF REG3G
266 ORF17_2_78763526_78765449_78792347_78798562_FF REG3G
267 ORF17_21_17393292_17394472_17434190_17435748_RR CXADR
268 ORF17_21_17393292_17394472_17434190_17435748_RR CXADR
269 ORF17_4_37859966_37862832_37927829_37933173_FF GAFA3; PGM2; PTTG2; TBC1D1; rs17578878; rs35859249
270 ORF17_4_37859966_37862832_37927829_37933173_FF GAFA3; PGM2; PTTG2; TBC1D1; rs17578878; rs35859249
271 ORF17_7_23187280_23192079_23219086_23222886_FR NUPL2; rs858249
272 ORF17_7_23187280_23192079_23219086_23222886_FR NUPL2; rs858249
273 ORF17_8_65560550_65562514_65630980_65632323_FR ARMC1; rs6991838
274 ORF17_8_65560550_65562514_65630980_65632323_FR ARMC1; rs6991838
275 ORF17_8_88542085_88553888_88592759_88597112_RF rs10504861; rs7838490; rs7819570; rs11995572
276 ORF17_8_88542085_88553888_88592759_88597112_RF rs10504861; rs7838490; rs7819570; rs11995572
277 ORF170_2_56323476_56329636_56390760_56394124_FF CCDC85A; rs186920977; rs6747380; rs17268785
278 ORF170_2_56323476_56329636_56390760_56394124_FF CCDC85A; rs186920977; rs6747380; rs17268785
279 ORF171_3_63280859_63282281_63308360_63313318_FR SYNPR; rs13098482
280 ORF171_3_63280859_63282281_63308360_63313318_FR SYNPR; rs13098482
281 ORF171_8_27764811_27768513_27798255_27800731_RF CCDC25; ESCO2; rs80359869; rs80359844; rs80359845; rs80359846; rs80359847; rs80359848; rs80359849; rs80359850; rs80359851; rs80359852; rs80359853; rs80359854; rs80359855; rs80359856; rs80359857; rs797045565; rs797045566; rs80359858; rs80359859; rs80359861; rs80359862; rs146312522; rs80359863; rs80359864; rs80359865; rs80359866; rs80359867; rs80359868
282 ORF171_8_27764811_27768513_27798255_27800731_RF CCDC25; ESCO2; rs80359869; rs80359844; rs80359845; rs80359846; rs80359847; rs80359848; rs80359849; rs80359850; rs80359851; rs80359852; rs80359853; rs80359854; rs80359855; rs80359856; rs80359857; rs797045565; rs797045566; rs80359858; rs80359859; rs80359861; rs80359862; rs146312522; rs80359863; rs80359864; rs80359865; rs80359866; rs80359867; rs80359868
283 ORF173_8_113409304_113413871_113438847_113446082_FF CSMD3; rs189590409
284 ORF173_8_113409304_113413871_113438847_113446082_FF CSMD3; rs189590409
285 ORF176_12_96187243_96188661_96237099_96241349_RF CDK17; ELK3; rs4762284
286 ORF176_12_96187243_96188661_96237099_96241349_RF CDK17; ELK3; rs4762284
表1.d1
   Probe_Count _Total Probe_Count _Sig HyperG_Stats
213 NA NA NA
214 NA NA NA
215 55 5; 5 0.042810093; 0.05348201
216 55 5; 5 0.042810093; 0.05348201
217 121 1; 1 0.039588815; 0.028906509
218 121 1; 1 0.039588815; 0.028906509
219 34; 34 3; 3; 3; 3 0.103367502; 0.117734198; 0.103367502; 0.117734198
220 34; 34 3; 3; 3; 3 0.103367502; 0.117734198; 0.103367502; 0.117734198
221 13 1; 1 0.314642613; 0.32680192
222 13 1; 1 0.314642613; 0.32680192
223 16; 16 1; 2; 1; 2 0.343724359; 0.116490918; 0.343724359; 0.116490918
224 16; 16 1; 2; 1; 2 0.343724359; 0.116490918; 0.343724359; 0.116490918
225 30 3; 1 0.082195447; 0.363021342
226 30 3; 1 0.082195447; 0.363021342
227 124; 112 3; 3; 3; 3 0.149414204; 0.126913559; 0.17713842; 0.156487188
228 124; 112 3; 3; 3; 3 0.149414204; 0.126913559; 0.17713842; 0.156487188
229 57 4; 2 0.110951788; 0.26588291
230 57 4; 2 0.110951788; 0.26588291
231 30 4; 5 0.022454364; 0.006393518
232 30 4; 5 0.022454364; 0.006393518
233 68 3; 4 0.224345313; 0.163371308
234 68 3; 4 0.224345313; 0.163371308
235 NA NA NA
236 NA NA NA
237 78 2; 4 0.222357541; 0.186212358
238 78 2; 4 0.222357541; 0.186212358
239 10 1; 1 0.272678156; 0.285987033
240 10 1; 1 0.272678156; 0.285987033
241 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
242 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
243 20 1; 2 0.366490901; 0.155331399
244 20 1; 2 0.366490901; 0.155331399
245 13; 36 1; 1; 2; 3 0.314642613; 0.32680192; 0.247980559; 0.12891994
246 13; 36 1; 1; 2; 3 0.314642613; 0.32680192; 0.247980559; 0.12891994
247 28; 28 1; 2; 1; 2 0.373281001; 0.219149094; 0.373281001; 0.219149094
248 28; 28 1; 2; 1; 2 0.373281001; 0.219149094; 0.373281001; 0.219149094
249 7; 12 1; 1; 1; 1 0.215038813; 0.227740664; 0.302214299; 0.314913912
250 7; 12 1; 1; 1; 1 0.215038813; 0.227740664; 0.302214299; 0.314913912
251 44 4; 3 0.063857117; 0.169607427
252 44 4; 3 0.063857117; 0.169607427
253 30 2; 2 0.21731878; 0.231426351
254 30 2; 2 0.21731878; 0.231426351
255 52; 88 1; 1; 1; 1 0.266738689; 0.244043749; 0.107508983; 0.08745761
256 52; 88 1; 1; 1; 1 0.266738689; 0.244043749; 0.107508983; 0.08745761
257 81; 71 1; 2; 1; 2 0.130826821; 0.192025586; 0.170848338; 0.226583412
258 81; 71 1; 2; 1; 2 0.130826821; 0.192025586; 0.170848338; 0.226583412
259 41 2; 2 0.26460109; 0.271883499
260 41 2; 2 0.26460109; 0.271883499
261 45 5; 5 0.022343156; 0.028833151
262 45 5; 5 0.022343156; 0.028833151
263 3 1; 1 0.108032075; 0.115907508
264 3 1; 1 0.108032075; 0.115907508
265 3 3; 2 0; 0.001770535
266 3 3; 2 0; 0.001770535
267 45 6; 1 0.006017292; 0.285503815
268 45 6; 1 0.006017292; 0.285503815
269 37; 37; 16; 40 5; 8; 5; 8; 1; 2; 2; 3 0.010942367; 0.000107113; 0.010942367; 0.000107113; 0.343724359; 0.116490918; 0.261899069; 0.150241062
270 37; 37; 16; 40 5; 8; 5; 8; 1; 2; 2; 3 0.010942367; 0.000107113; 0.010942367; 0.000107113; 0.343724359; 0.116490918; 0.261899069; 0.150241062
271 51 1; 1 0.272236181; 0.249886334
272 51 1; 1 0.272236181; 0.249886334
273 48 5; 4 0.02780594; 0.092112824
274 48 5; 4 0.02780594; 0.092112824
275 NA NA NA
276 NA NA NA
277 35 4; 2 0.035189793; 0.255336195
278 35 4; 2 0.035189793; 0.255336195
279 41 2; 1 0.26460109; 0.309016356
280 41 2; 1 0.26460109; 0.309016356
281 64; 45 1; 1; 1; 1 0.203553997; 0.179089876; 0.305019886; 0.285503815
282 64; 45 1; 1; 1; 1 0.203553997; 0.179089876; 0.305019886; 0.285503815
283 12 1; 2 0.302214299; 0.076075379
284 12 1; 2 0.302214299; 0.076075379
285 13; 13 1; 1; 2; 3 0.314642613; 0.32680192; 0.076537269; 0.013853987
286 13; 13 1; 1; 2; 3 0.314642613; 0.32680192; 0.076537269; 0.013853987
表1.d2
   FDR_HyperG Percent_Sig logFC AveExpr
213 NA NA 0.555765552 0.555765552
214 NA NA 0.492575943 0.492575943
215 0.375519541; 0.376115439 9.09; 9.09 0.984216332 0.984216332
216 0.375519541; 0.376115439 9.09; 9.09 0.904733665 0.904733665
217 0.375519541; 0.376115439 0.83; 0.83 0.679292964 0.679292964
218 0.375519541; 0.376115439 0.83; 0.83 0.675599569 0.675599569
219 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.82; 8.82; 8.82; 8.82 0.631496413 0.631496413
220 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.82; 8.82; 8.82; 8.82 0.624545129 0.624545129
221 0.375519541; 0.376115439 7.69; 7.69 0.686983289 0.686983289
222 0.375519541; 0.376115439 7.69; 7.69 0.655999636 0.655999636
223 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.25; 12.5; 6.25; 12.5 0.70992284 0.70992284
224 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.25; 12.5; 6.25; 12.5 0.685092872 0.685092872
225 0.375519541; 0.376115439 10; 3.33 0.579134595 0.579134595
226 0.375519541; 0.376115439 10; 3.33 0.525435803 0.525435803
227 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.42; 2.42; 2.68; 2.68 0.583374913 0.583374913
228 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.42; 2.42; 2.68; 2.68 0.546729205 0.546729205
229 0.375519541; 0.376115439 7.02; 3.51 1.050848942 1.050848942
230 0.375519541; 0.376115439 7.02; 3.51 0.997588794 0.997588794
231 0.375519541; 0.217379602 13.33; 16.67 0.718226025 0.718226025
232 0.375519541; 0.217379602 13.33; 16.67 0.518370475 0.518370475
233 0.375519541; 0.376115439 4.41; 5.88 0.587276619 0.587276619
234 0.375519541; 0.376115439 4.41; 5.88 0.553712202 0.553712202
235 NA NA 0.528734129 0.528734129
236 NA NA 0.519765114 0.519765114
237 0.375519541; 0.376115439 2.56; 5.13 0.657404682 0.657404682
238 0.375519541; 0.376115439 2.56; 5.13 0.652559324 0.652559324
239 0.375519541; 0.376115439 10; 10 0.615586809 0.615586809
240 0.375519541; 0.376115439 10; 10 0.562580238 0.562580238
241 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.755371177 0.755371177
242 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.610723495 0.610723495
243 0.375519541; 0.376115439 5; 10 0.726687643 0.726687643
244 0.375519541; 0.376115439 5; 10 0.684934753 0.684934753
245 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.69; 7.69; 5.56; 8.33 0.592746388 0.592746388
246 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.69; 7.69; 5.56; 8.33 0.50869677 0.50869677
247 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.57; 7.14; 3.57; 7.14 0.57957564 0.57957564
248 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.57; 7.14; 3.57; 7.14 0.569686123 0.569686123
249 0.375519541; 0.376115439; 0.375519541; 0.376115439 14.29; 14.29; 8.33; 8.33 0.731224565 0.731224565
250 0.375519541; 0.376115439; 0.375519541; 0.376115439 14.29; 14.29; 8.33; 8.33 0.634525197 0.634525197
251 0.375519541; 0.376115439 9.09; 6.82 0.60784154 0.60784154
252 0.375519541; 0.376115439 9.09; 6.82 0.521330725 0.521330725
253 0.375519541; 0.376115439 6.67; 6.67 0.913741587 0.913741587
254 0.375519541; 0.376115439 6.67; 6.67 0.742478856 0.742478856
255 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.92; 1.92; 1.14; 1.14 0.968228342 0.968228342
256 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.92; 1.92; 1.14; 1.14 0.860213569 0.860213569
257 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.23; 2.47; 1.41; 2.82 0.63321845 0.63321845
258 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.23; 2.47; 1.41; 2.82 0.620644012 0.620644012
259 0.375519541; 0.376115439 4.88; 4.88 0.687605502 0.687605502
260 0.375519541; 0.376115439 4.88; 4.88 0.672032414 0.672032414
261 0.375519541; 0.376115439 11.11; 11.11 0.727600901 0.727600901
262 0.375519541; 0.376115439 11.11; 11.11 0.657100455 0.657100455
263 0.375519541; 0.376115439 33.33; 33.33 0.716018427 0.716018427
264 0.375519541; 0.376115439 33.33; 33.33 0.648215413 0.648215413
265 0; 0.082088441 100; 100 0.608572853 0.608572853
266 0; 0.082088441 100; 100 0.581521773 0.581521773
267 0.242080288; 0.376115439 13.33; 2.22 0.784915067 0.784915067
268 0.242080288; 0.376115439 13.33; 2.22 0.643748555 0.643748555
269 0.357678624; 0.013656923; 0.357678624; 0.013656923; 0.375519541; 0.376115439; 0.375519541; 0.376115439 13.51; 21.62; 13.51; 21.62; 6.25; 12.5; 5; 7.5 0.732003297 0.732003297
270 0.357678624; 0.013656923; 0.357678624; 0.013656923; 0.375519541; 0.376115439; 0.375519541; 0.376115439 13.51; 21.62; 13.51; 21.62; 6.25; 12.5; 5; 7.5 0.59203768 0.59203768
271 0.375519541; 0.376115439 1.96; 1.96 0.837432144 0.837432144
272 0.375519541; 0.376115439 1.96; 1.96 0.75493067 0.75493067
273 0.375519541; 0.376115439 10.42; 8.33 0.78755073 0.78755073
274 0.375519541; 0.376115439 10.42; 8.33 0.702870259 0.702870259
275 NA NA 1.046784237 1.046784237
276 NA NA 0.973096611 0.973096611
277 0.375519541; 0.376115439 11.43; 5.71 0.623032467 0.623032467
278 0.375519541; 0.376115439 11.43; 5.71 0.513312306 0.513312306
279 0.375519541; 0.376115439 4.88; 2.44 0.715626316 0.715626316
280 0.375519541; 0.376115439 4.88; 2.44 0.653108277 0.653108277
281 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.56; 1.56; 2.22; 2.22 0.542949491 0.542949491
282 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.56; 1.56; 2.22; 2.22 0.541851946 0.541851946
283 0.375519541; 0.376115439 8.33; 16.67 0.64477187 0.64477187
284 0.375519541; 0.376115439 8.33; 16.67 0.525770097 0.525770097
285 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.69; 7.69; 15.38; 23.08 0.711747903 0.711747903
286 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.69; 7.69; 15.38; 23.08 0.691863386 0.691863386
表1.d3
   t P值 adj.P.Val B FC FC_1 LS
213 7.260165345 0.0000103 0.00032205 3.676586181 1.46994844 1.46994844 1
214 5.339439015 0.000177541 0.001246386 0.664445729 1.406954763 1.406954763 1
215 16.23202167 0.00000000169 0.00000233 12.26654232 1.978238447 1.978238447 1
216 14.18093827 0.00000000751 0.00000251 10.90523174 1.872198837 1.872198837 1
217 11.80434759 0.0000000613 0.0000138 8.841672429 1.601354771 1.601354771 1
218 12.02061316 0.0000000482 0.00000654 9.072614972 1.597260439 1.597260439 1
219 10.02330272 0.000000354 0.0000209 7.064564936 1.549171014 1.549171014 1
220 9.704432552 0.000000517 0.0000497 6.719924741 1.541724654 1.541724654 1
221 19.221459 0.000000000240 0.00000103 14.01108919 1.609913627 1.609913627 1
222 11.9389033 0.000000052 0.00000676 8.996907807 1.575707374 1.575707374 1
223 18.5672982 0.000000000359 0.00000126 13.66014624 1.635716631 1.635716631 1
224 15.02118219 0.00000000390 0.00000178 11.53971631 1.607805479 1.607805479 1
225 10.45337524 0.000000232 0.0000309 7.522312852 1.493952827 1.493952827 1
226 5.727638406 0.0000955 0.000800788 1.305056222 1.439368313 1.439368313 1
227 13.09171547 0.0000000185 0.00000396 10.02014744 1.49835026 1.49835026 1
228 15.57027442 0.00000000272 0.00000287 11.82659932 1.460770165 1.460770165 1
229 17.46312676 0.000000000729 0.00000168 13.03019046 2.071748592 2.071748592 1
230 19.47078279 0.000000000195 0.000000498 14.33533501 1.996660151 1.996660151 1
231 10.18859459 0.000000306 0.0000364 7.244811857 1.645157862 1.645157862 1
232 7.424246798 0.00000808 0.000150679 3.857176398 1.432336509 1.432336509 1
233 9.162816338 0.000000951 0.0000719 6.104525201 1.502407967 1.502407967 1
234 9.514869484 0.000000619 0.0000296 6.495454048 1.467857789 1.467857789 1
235 9.57959508 0.000000576 0.0000283 6.569345699 1.442662798 1.442662798 1
236 5.872975811 0.0000773 0.001227022 1.607969852 1.433721804 1.433721804 1
237 12.8429881 0.000000024 0.00000869 9.757379266 1.577242709 1.577242709 1
238 14.62271022 0.00000000530 0.00000212 11.24377521 1.571954352 1.571954352 1
239 2.726005115 0.018424033 0.04224655 -4.03847984 1.532181078 1.532181078 1
240 9.344586893 0.000000773 0.0000634 6.314497427 1.476908285 1.476908285 1
241 5.878256372 0.0000766 0.001219955 1.616360692 1.688065842 1.688065842 1
242 6.610580495 0.0000252 0.000320602 2.6830041 1.527024802 1.527024802 1
243 15.96846986 0.00000000204 0.00000251 12.09392263 1.654835306 1.654835306 1
244 12.97764894 0.0000000205 0.00000415 9.92304991 1.607629273 1.607629273 1
245 14.16069263 0.00000000799 0.00000491 10.81250789 1.508114941 1.508114941 1
246 10.13226105 0.000000315 0.0000195 7.183226122 1.422764389 1.422764389 1
247 12.12472668 0.0000000455 0.000012 9.132672207 1.494409613 1.494409613 1
248 6.558598076 0.0000272 0.000336042 2.604916707 1.484200628 1.484200628 1
249 14.28865646 0.00000000721 0.00000475 10.90919894 1.660047548 1.660047548 1
250 12.23181776 0.0000000397 0.00000589 9.265978503 1.552426749 1.552426749 1
251 9.36635516 0.000000732 0.000033 6.324274905 1.523977434 1.523977434 1
252 9.435204652 0.000000697 0.0000594 6.417862317 1.435278522 1.435278522 1
253 13.53412308 0.0000000133 0.00000636 10.3246933 1.883925072 1.883925072 1
254 13.06000286 0.0000000191 0.000004 9.993240024 1.673048022 1.673048022 1
255 9.932830648 0.000000403 0.0000425 6.970408871 1.956436576 1.956436576 1
256 11.97244336 0.0000000504 0.00000668 9.028045246 1.815307019 1.815307019 1
257 13.38530727 0.0000000151 0.00000688 10.20520537 1.551021248 1.551021248 1
258 16.21810555 0.00000000162 0.00000118 12.3786542 1.537561388 1.537561388 1
259 13.08809821 0.0000000194 0.00000782 9.96222989 1.610608109 1.610608109 1
260 17.49673479 0.000000000675 0.000000801 13.19969713 1.59331599 1.59331599 1
261 11.3234876 0.0000000934 0.00000943 8.40997782 1.655883186 1.655883186 1
262 10.33956834 0.000000261 0.0000331 7.403844592 1.576910145 1.576910145 1
263 13.37427123 0.0000000146 0.00000347 10.25695904 1.642642382 1.642642382 1
264 10.50748087 0.000000219 0.00003 7.578213938 1.567228364 1.567228364 1
265 13.60186555 0.000000012 0.00000309 10.44395365 1.524750145 1.524750145 1
266 11.90195534 0.0000000559 0.0000134 8.931166808 1.496426866 1.496426866 1
267 11.22011494 0.000000107 0.0000193 8.290092068 1.722990882 1.722990882 1
268 9.919790976 0.000000396 0.0000224 6.95077435 1.562383432 1.562383432 1
269 11.68690688 0.0000000684 0.0000148 8.73300385 1.660943844 1.660943844 1
270 12.30985713 0.000000037 0.00000569 9.336589654 1.507374278 1.507374278 1
271 14.15860604 0.000000008 0.00000491 10.81092318 1.786866862 1.786866862 1
272 17.42726451 0.000000000707 0.000000818 13.15692781 1.687550493 1.687550493 1
273 11.35923764 0.0000000902 0.00000925 8.44490275 1.726141495 1.726141495 1
274 15.50537662 0.00000000285 0.00000294 11.7822691 1.627739982 1.627739982 1
275 6.671069956 0.0000235 0.000553643 2.831017554 2.065919783 2.065919783 1
276 9.939739376 0.000000387 0.000022 6.972784712 1.96304958 1.96304958 1
277 10.48658633 0.000000224 0.0000303 7.556657964 1.540109008 1.540109008 1
278 10.6808888 0.000000177 0.0000139 7.763842221 1.427323451 1.427323451 1
279 16.7420602 0.00000000112 0.000000998 12.72395428 1.642195988 1.642195988 1
280 17.0717273 0.000000000946 0.00000189 12.79475608 1.572552603 1.572552603 1
281 11.71698674 0.0000000665 0.0000146 8.760940678 1.456948105 1.456948105 1
282 19.31548313 0.000000000214 0.000000503 14.25125578 1.455840138 1.455840138 1
283 10.21192721 0.000000289 0.0000186 7.269270408 1.563492036 1.563492036 1
284 11.53933542 0.0000000787 0.0000162 8.59489991 1.439701874 1.439701874 1
285 11.4882289 0.0000000797 0.00000864 8.57005061 1.637787183 1.637787183 1
286 12.53535025 0.0000000314 0.00000988 9.494366239 1.615368583 1.615368583 1
表1.d4
      探針序列 探針 位置
偵測到之環 60 mer Chr
213 mHC TTTGTGTTTCATGACCTGCTAAATACTTTCGAAAGTATTTAGCAGGTCATGAAACACAAA 14
214 sHC TTTGTGTTTCATGACCTGCTAAATACTTTCGAAAGTATTTAGCAGGTCATGAAACACAAA 14
215 mHC TTATATCATTATTTTATAATGTATTCCTTCGAAATAAGCACTTAGGAAGTTTGAGTAAAT 3
216 sHC TTATATCATTATTTTATAATGTATTCCTTCGAAATAAGCACTTAGGAAGTTTGAGTAAAT 3
217 mHC TCTGTCATCTTCTTACGTATTAACATTATCGAATATTTGTGATTTGAAATTTGTCCTGGT 7
218 sHC TCTGTCATCTTCTTACGTATTAACATTATCGAATATTTGTGATTTGAAATTTGTCCTGGT 7
219 sHC TTTCTTGTATTTCATTATGTACATCTATTCGATAAAACTTTTTTTCTATAGTTCTCTGAC 6
220 mHC TTTCTTGTATTTCATTATGTACATCTATTCGATAAAACTTTTTTTCTATAGTTCTCTGAC 6
221 mHC GTTTCATTTCATATTTTCACAAAAGATCTCGAATTATGTGCAGTACTACAATAGTAATGG 18
222 sHC GTTTCATTTCATATTTTCACAAAAGATCTCGAATTATGTGCAGTACTACAATAGTAATGG 18
223 mHC AACATATATAAGCTTTTTACTTAAAAGTTCGATAATACTGTATTGTAGTCAGAATGTTTG 5
224 sHC AACATATATAAGCTTTTTACTTAAAAGTTCGATAATACTGTATTGTAGTCAGAATGTTTG 5
225 mHC CACTTAACAATATAATGTATAAATCTCCTCGAAGAAAATGCTGAAGAATATCTTAATGAC 5
226 sHC CACTTAACAATATAATGTATAAATCTCCTCGAAGAAAATGCTGAAGAATATCTTAATGAC 5
227 sHC TGGTAAATTGGAGCAGGTGACCTGGGAGTCGAGGCAGCTGCAGGATTTAAATTGGCTGAG 1
228 mHC TGGTAAATTGGAGCAGGTGACCTGGGAGTCGAGGCAGCTGCAGGATTTAAATTGGCTGAG 1
229 mHC CAAAGTACTACTTTAATTTATGACATAATCGAACACAGAAGTATTTATCTGAAAAGTGGA 2
230 sHC CAAAGTACTACTTTAATTTATGACATAATCGAACACAGAAGTATTTATCTGAAAAGTGGA 2
231 mHC TTTAAAATTGTTGACAGAAAATATATTATCGACATATATTTACCTACATAGAAGAGTATG 3
232 sHC TTTAAAATTGTTGACAGAAAATATATTATCGACATATATTTACCTACATAGAAGAGTATG 3
233 mHC ATATGATTATGGTTATAACTAAACTATATCGAACTTACTTCATTAACCTTAAAAAATACA 4
234 sHC ATATGATTATGGTTATAACTAAACTATATCGAACTTACTTCATTAACCTTAAAAAATACA 4
235 sHC TATCTAGATGTAGGTATATATTTATCTATCGACTTTCAAGCAAAGAAAATGCAAATATGC 5
236 mHC TATCTAGATGTAGGTATATATTTATCTATCGACTTTCAAGCAAAGAAAATGCAAATATGC 5
237 mHC CTGGAAGCCTTACAGATGACATAAACAATCGAATAAATAATGGAGCTAAATGGCATATAT 8
238 sHC CTGGAAGCCTTACAGATGACATAAACAATCGAATAAATAATGGAGCTAAATGGCATATAT 8
239 sHC CTAATTTCATTTCTTTTTAGTTTCCTCTTCGATACCTTGAATTATAATACTTGTTCTGAT 8
240 mHC CTAATTTCATTTCTTTTTAGTTTCCTCTTCGATACCTTGAATTATAATACTTGTTCTGAT 8
241 mHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGAGGTTCAGCACCGTAGGTGTAGCGCAGGC 9
242 sHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGAGGTTCAGCACCGTAGGTGTAGCGCAGGC 9
243 mHC TTCAATTGTACTGTTAATATTTTATTTCTCGAATAAATAATCCTCTTCTTTTCCTCTTTC 5
244 sHC TTCAATTGTACTGTTAATATTTTATTTCTCGAATAAATAATCCTCTTCTTTTCCTCTTTC 5
245 mHC ATATGTAGATATATGTTTTCAAGCAATATCGAAGAGTAGTACCTTATCAAAGCTTTGCAG 14
246 sHC ATATGTAGATATATGTTTTCAAGCAATATCGAAGAGTAGTACCTTATCAAAGCTTTGCAG 14
247 mHC AATAGTATAATTAAAATAGTAAAGAAAATCGATATACCATAGGTGTATAGTAGGTTATGC 6
248 sHC AATAGTATAATTAAAATAGTAAAGAAAATCGATATACCATAGGTGTATAGTAGGTTATGC 6
249 mHC GTACATTTAATGAAACTACTAAAATATTTCGAATAGAAATACAATGCCAGACACATAAGT 19
250 sHC GTACATTTAATGAAACTACTAAAATATTTCGAATAGAAATACAATGCCAGACACATAAGT 19
251 sHC GATGATCAACATTCATTGAGAATGAAAATCGATTTATAACAAAAATAAACACTGTAGAAA 1
252 mHC GATGATCAACATTCATTGAGAATGAAAATCGATTTATAACAAAAATAAACACTGTAGAAA 1
253 mHC TTACTCACTTATTAGTCTATTAAGATTTTCGATATAAAACTTATAAATGGTTTATTTCTG 7
254 sHC TTACTCACTTATTAGTCTATTAAGATTTTCGATATAAAACTTATAAATGGTTTATTTCTG 7
255 mHC ACATATATATATATATATTTAATATACATCGATAGATAATTGTCTTCCAGAATATTTTAA 12
256 sHC ACATATATATATATATATTTAATATACATCGATAGATAATTGTCTTCCAGAATATTTTAA 12
257 mHC AATTAGTATTTATTTTTTCTATTTTATTTCGAATGAATGTAACAGGAAAGCAGAAAAGCA 14
258 sHC AATTAGTATTTATTTTTTCTATTTTATTTCGAATGAATGTAACAGGAAAGCAGAAAAGCA 14
259 mHC TTATTATAAATAAGTGTATATGTGAAATTCGATGTGTTTCTATTTTTAAAACCTCTTAAC 1
260 sHC TTATTATAAATAAGTGTATATGTGAAATTCGATGTGTTTCTATTTTTAAAACCTCTTAAC 1
261 sHC CCTTTCAAATTTAGATTTAAAATCTATTTCGATGCTACTAAAAGCAGCAATAATACTTTC 1
262 mHC CCTTTCAAATTTAGATTTAAAATCTATTTCGATGCTACTAAAAGCAGCAATAATACTTTC 1
263 sHC TTTAAACTATTTTTAAAAGAGTACTTTTTCGACTTGGTACAAAATCAAAGTAAGAAGTAT 11
264 mHC TTTAAACTATTTTTAAAAGAGTACTTTTTCGACTTGGTACAAAATCAAAGTAAGAAGTAT 11
265 sHC CTATATTGTAGCTCTATTTTCTCTAAATTCGAAGAATCATGCCTTAATGGATTGAAACAA 2
266 mHC CTATATTGTAGCTCTATTTTCTCTAAATTCGAAGAATCATGCCTTAATGGATTGAAACAA 2
267 mHC TTTTTATTTTATCTTTTATTTTATTTTTTCGAATTCATGTTTTTTCTCTTGGAATTTTCT 21
268 sHC TTTTTATTTTATCTTTTATTTTATTTTTTCGAATTCATGTTTTTTCTCTTGGAATTTTCT 21
269 mHC CCTACCAGAACTCTTAAATCTATAATATTCGAAATTTTATTATCTTAGGTGAGAAAATAG 4
270 sHC CCTACCAGAACTCTTAAATCTATAATATTCGAAATTTTATTATCTTAGGTGAGAAAATAG 4
271 mHC GTAACTACTACATTTTAGTATATTTCTTTCGATCAGAAGTTAACTCTAATTGAATCATAG 7
272 sHC GTAACTACTACATTTTAGTATATTTCTTTCGATCAGAAGTTAACTCTAATTGAATCATAG 7
273 sHC TATCTCTATGTAATAATCACTAAAAGTATCGATTCATGCTTGGTTGAATCAGACAATGTC 8
274 mHC TATCTCTATGTAATAATCACTAAAAGTATCGATTCATGCTTGGTTGAATCAGACAATGTC 8
275 mHC ATCTCATTTAACAAAAGATGAGTAAAAATCGATTTTTTAACGAATGTATCTGAAAATAGC 8
276 sHC ATCTCATTTAACAAAAGATGAGTAAAAATCGATTTTTTAACGAATGTATCTGAAAATAGC 8
277 mHC TCGCTTTTCTTATATAAAGGAACATTTCTCGAGTGGTAATGTACCAATCATTCATTGATT 2
278 sHC TCGCTTTTCTTATATAAAGGAACATTTCTCGAGTGGTAATGTACCAATCATTCATTGATT 2
279 sHC TTCTCATGTTTCTTTTTCTGACTAAATGTCGATTGAGATATAATTGACATAATAAATTAC 3
280 mHC TTCTCATGTTTCTTTTTCTGACTAAATGTCGATTGAGATATAATTGACATAATAAATTAC 3
281 mHC TCTGTGATTAATGGATAAATGTGATATATCGACAGCATTTACTATTCATGTTACTTCATT 8
282 sHC TCTGTGATTAATGGATAAATGTGATATATCGACAGCATTTACTATTCATGTTACTTCATT 8
283 sHC TTTATTTACCTTCTTGTATGAATATTGATCGAATCTCAACATCCTTAACATAGTTACATC 8
284 mHC TTTATTTACCTTCTTGTATGAATATTGATCGAATCTCAACATCCTTAACATAGTTACATC 8
285 sHC ATATGCTTTTTTTAAATTACAAAACTTATCGATCATTTTTTAAATTTAAAACTCTGAAGC 12
286 mHC ATATGCTTTTTTTAAATTACAAAACTTATCGATCATTTTTTAAATTTAAAACTCTGAAGC 12
表1.d5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
213 106693397 106693428 106739902 106739933 14 106693397 106697398 106739902 106743903
214 106693397 106693428 106739902 106739933 14 106693397 106697398 106739902 106743903
215 65839372 65839403 65903659 65903690 3 65835402 65839403 65899689 65903690
216 65839372 65839403 65903659 65903690 3 65835402 65839403 65899689 65903690
217 131130568 131130599 131219450 131219481 7 131130568 131134569 131219450 131223451
218 131130568 131130599 131219450 131219481 7 131130568 131134569 131219450 131223451
219 73690117 73690148 73758266 73758297 6 73686147 73690148 73754296 73758297
220 73690117 73690148 73758266 73758297 6 73686147 73690148 73754296 73758297
221 3106299 3106330 3129940 3129971 18 3106299 3110300 3129940 3133941
222 3106299 3106330 3129940 3129971 18 3106299 3110300 3129940 3133941
223 36141976 36142007 36164938 36164969 5 36138006 36142007 36160968 36164969
224 36141976 36142007 36164938 36164969 5 36138006 36142007 36160968 36164969
225 26999889 26999920 27044575 27044606 5 26999889 27003890 27040605 27044606
226 26999889 26999920 27044575 27044606 5 26999889 27003890 27040605 27044606
227 36409666 36409697 36433268 36433299 1 36409666 36413667 36433268 36437269
228 36409666 36409697 36433268 36433299 1 36409666 36413667 36433268 36437269
229 66448986 66449017 66470757 66470788 2 66445016 66449017 66470757 66474758
230 66448986 66449017 66470757 66470788 2 66445016 66449017 66470757 66474758
231 107626100 107626131 107708851 107708882 3 107626100 107630101 107708851 107712852
232 107626100 107626131 107708851 107708882 3 107626100 107630101 107708851 107712852
233 175829279 175829310 175892267 175892298 4 175829279 175833280 175892267 175896268
234 175829279 175829310 175892267 175892298 4 175829279 175833280 175892267 175896268
235 6226839 6226870 6283431 6283462 5 6222869 6226870 6283431 6287432
236 6226839 6226870 6283431 6283462 5 6222869 6226870 6283431 6287432
237 52380368 52380399 52462030 52462061 8 52380368 52384369 52462030 52466031
238 52380368 52380399 52462030 52462061 8 52380368 52384369 52462030 52466031
239 67971637 67971668 68010294 68010325 8 67971637 67975638 68010294 68014295
240 67971637 67971668 68010294 68010325 8 67971637 67975638 68010294 68014295
241 38686830 38686861 38768696 38768727 9 38682860 38686861 38768696 38772697
242 38686830 38686861 38768696 38768727 9 38682860 38686861 38768696 38772697
243 93565548 93565579 93583739 93583770 5 93561578 93565579 93579769 93583770
244 93565548 93565579 93583739 93583770 5 93561578 93565579 93579769 93583770
245 51804670 51804701 51892245 51892276 14 51804670 51808671 51888275 51892276
246 51804670 51804701 51892245 51892276 14 51804670 51808671 51888275 51892276
247 146094504 146094535 146155392 146155423 6 146094504 146098505 146155392 146159393
248 146094504 146094535 146155392 146155423 6 146094504 146098505 146155392 146159393
249 36776229 36776260 36803032 36803063 19 36772259 36776260 36803032 36807033
250 36776229 36776260 36803032 36803063 19 36772259 36776260 36803032 36807033
251 229859020 229859051 229911260 229911291 1 229859020 229863021 229907290 229911291
252 229859020 229859051 229911260 229911291 1 229859020 229863021 229907290 229911291
253 45370280 45370311 45391022 45391053 7 45366310 45370311 45387052 45391053
254 45370280 45370311 45391022 45391053 7 45366310 45370311 45387052 45391053
255 130198001 130198032 130252465 130252496 12 130194031 130198032 130248495 130252496
256 130198001 130198032 130252465 130252496 12 130194031 130198032 130248495 130252496
257 89880613 89880644 89952946 89952977 14 89880613 89884614 89952946 89956947
258 89880613 89880644 89952946 89952977 14 89880613 89884614 89952946 89956947
259 206310392 206310423 206385274 206385305 1 206306422 206310423 206381304 206385305
260 206310392 206310423 206385274 206385305 1 206306422 206310423 206381304 206385305
261 76098903 76098934 76127632 76127663 1 76094933 76098934 76123662 76127663
262 76098903 76098934 76127632 76127663 1 76094933 76098934 76123662 76127663
263 128978278 128978309 129021767 129021798 11 128974308 128978309 129021767 129025768
264 128978278 128978309 129021767 129021798 11 128974308 128978309 129021767 129025768
265 78765418 78765449 78798531 78798562 2 78761448 78765449 78794561 78798562
266 78765418 78765449 78798531 78798562 2 78761448 78765449 78794561 78798562
267 17393292 17393323 17434190 17434221 21 17393292 17397293 17434190 17438191
268 17393292 17393323 17434190 17434221 21 17393292 17397293 17434190 17438191
269 37862801 37862832 37933142 37933173 4 37858831 37862832 37929172 37933173
270 37862801 37862832 37933142 37933173 4 37858831 37862832 37929172 37933173
271 23192048 23192079 23219086 23219117 7 23188078 23192079 23219086 23223087
272 23192048 23192079 23219086 23219117 7 23188078 23192079 23219086 23223087
273 65562483 65562514 65630980 65631011 8 65558513 65562514 65630980 65634981
274 65562483 65562514 65630980 65631011 8 65558513 65562514 65630980 65634981
275 88542085 88542116 88597081 88597112 8 88542085 88546086 88593111 88597112
276 88542085 88542116 88597081 88597112 8 88542085 88546086 88593111 88597112
277 56329605 56329636 56394093 56394124 2 56325635 56329636 56390123 56394124
278 56329605 56329636 56394093 56394124 2 56325635 56329636 56390123 56394124
279 63282250 63282281 63308360 63308391 3 63278280 63282281 63308360 63312361
280 63282250 63282281 63308360 63308391 3 63278280 63282281 63308360 63312361
281 27764811 27764842 27800700 27800731 8 27764811 27768812 27796730 27800731
282 27764811 27764842 27800700 27800731 8 27764811 27768812 27796730 27800731
283 113413840 113413871 113446051 113446082 8 113409870 113413871 113442081 113446082
284 113413840 113413871 113446051 113446082 8 113409870 113413871 113442081 113446082
285 96187243 96187274 96241318 96241349 12 96187243 96191244 96237348 96241349
286 96187243 96187274 96241318 96241349 12 96187243 96191244 96237348 96241349
表1.d6
   探針 PCR- 引子 1_ID PCR_ 引子 1
213 ORF152_14_106693397_106698909_106739902_106745380_RR OBD159_417 TTATGCCCCACCTTCTTCAGTGTAAT
214 ORF152_14_106693397_106698909_106739902_106745380_RR OBD159_417 TTATGCCCCACCTTCTTCAGTGTAAT
215 ORF153_3_65835051_65839403_65898255_65903690_FF OBD159_421 ACCTACTGTGCTGCCAGACATAGAAA
216 ORF153_3_65835051_65839403_65898255_65903690_FF OBD159_421 ACCTACTGTGCTGCCAGACATAGAAA
217 ORF153_7_131130568_131132000_131219450_131221740_RR OBD159_425 TCCCTTGAAAACCTGTGTCCAATGAC
218 ORF153_7_131130568_131132000_131219450_131221740_RR OBD159_425 TCCCTTGAAAACCTGTGTCCAATGAC
219 ORF154_6_73688989_73690148_73751804_73758297_FF OBD159_429 TCAGTGTTTGCTTTTCCCTTGAAT
220 ORF154_6_73688989_73690148_73751804_73758297_FF OBD159_429 TCAGTGTTTGCTTTTCCCTTGAAT
221 ORF155_18_3106299_3108561_3129940_3131675_RR OBD159_433 AGGTTGAAGTTGAAACACAGATGT
222 ORF155_18_3106299_3108561_3129940_3131675_RR OBD159_433 AGGTTGAAGTTGAAACACAGATGT
223 ORF155_5_36136424_36142007_36160830_36164969_FF OBD159_437 TTTTTAATAGTGCTTCAAA
224 ORF155_5_36136424_36142007_36160830_36164969_FF OBD159_437 TTTTTAATAGTGCTTCAAA
225 ORF158_5_26999889_27004744_27042244_27044606_RF OBD159_441 CTCTTTTATTTACCACTCCATTCTTCCA
226 ORF158_5_26999889_27004744_27042244_27044606_RF OBD159_441 CTCTTTTATTTACCACTCCATTCTTCCA
227 ORF16_1_36409666_36411937_36433268_36434547_RR OBD159_165 GAAGCGAGTTGCTGTCACTGGAG
228 ORF16_1_36409666_36411937_36433268_36434547_RR OBD159_165 GAAGCGAGTTGCTGTCACTGGAG
229 ORF16_2_66446190_66449017_66470757_66475654_FR OBD159_445 CCACTGTCAGGGAAATAGTTGAAGGA
230 ORF16_2_66446190_66449017_66470757_66475654_FR OBD159_445 CCACTGTCAGGGAAATAGTTGAAGGA
231 ORF16_3_107626100_107637571_107708851_107713617_RR OBD159_449 CAGAAAAGCCCAGGAAGGTATCAGAT
232 ORF16_3_107626100_107637571_107708851_107713617_RR OBD159_449 CAGAAAAGCCCAGGAAGGTATCAGAT
233 ORF16_4_175829279_175833051_175892267_175894404_RR OBD159_453 CCACTGACTTCACTGTTTAA
234 ORF16_4_175829279_175833051_175892267_175894404_RR OBD159_453 CCACTGACTTCACTGTTTAA
235 ORF16_5_6223946_6226870_6283431_6289065_FR OBD159_457 CTGTTCTCAGCAATGGAATCTCAGGT
236 ORF16_5_6223946_6226870_6283431_6289065_FR OBD159_457 CTGTTCTCAGCAATGGAATCTCAGGT
237 ORF16_8_52380368_52388099_52462030_52466077_RR OBD159_461 AGGGAGAGGAGACAGATGTTCTTTCT
238 ORF16_8_52380368_52388099_52462030_52466077_RR OBD159_461 AGGGAGAGGAGACAGATGTTCTTTCT
239 ORF16_8_67971637_67976278_68010294_68014710_RR OBD159_465 CACTGTTGTCTTATTGCCTTGCTCAG
240 ORF16_8_67971637_67976278_68010294_68014710_RR OBD159_465 CACTGTTGTCTTATTGCCTTGCTCAG
241 ORF16_9_38681931_38686861_38768696_38769724_FR OBD159_469 CAGAAGTTCACAGGCAGGGTGTC
242 ORF16_9_38681931_38686861_38768696_38769724_FR OBD159_469 CAGAAGTTCACAGGCAGGGTGTC
243 ORF160_5_93562856_93565579_93582366_93583770_FF OBD159_473 ATGCCCAGTCATAGGTGATAAGATTA
244 ORF160_5_93562856_93565579_93582366_93583770_FF OBD159_473 ATGCCCAGTCATAGGTGATAAGATTA
245 ORF162_14_51804670_51807147_51886119_51892276_RF OBD159_477 GTTCCTCTTGCTCCACTTGTCAACAG
246 ORF162_14_51804670_51807147_51886119_51892276_RF OBD159_477 GTTCCTCTTGCTCCACTTGTCAACAG
247 ORF162_6_146094504_146104695_146155392_146161780_RR OBD159_481 CACATACACAGGGTAACCTAAGGAAG
248 ORF162_6_146094504_146104695_146155392_146161780_RR OBD159_481 CACATACACAGGGTAACCTAAGGAAG
249 ORF163_19_36775089_36776260_36803032_36806792_FR OBD159_485 ATGATAGGCACATACTCTCCTCTG
250 ORF163_19_36775089_36776260_36803032_36806792_FR OBD159_485 ATGATAGGCACATACTCTCCTCTG
251 ORF164_1_229859020_229862315_229908605_229911291_RF OBD159_489 TGTCATTTTCACACCATCCTCCCCAT
252 ORF164_1_229859020_229862315_229908605_229911291_RF OBD159_489 TGTCATTTTCACACCATCCTCCCCAT
253 ORF164_7_45364155_45370311_45384350_45391053_FF OBD159_493 GAGTTTGGAGGTGTTCTCTGCCCTTT
254 ORF164_7_45364155_45370311_45384350_45391053_FF OBD159_493 GAGTTTGGAGGTGTTCTCTGCCCTTT
255 ORF166_12_130196441_130198032_130248318_130252496_FF OBD159_497 GCGGAGGGAGAGTCACGCAAGAT
256 ORF166_12_130196441_130198032_130248318_130252496_FF OBD159_497 GCGGAGGGAGAGTCACGCAAGAT
257 ORF166_14_89880613_89884758_89952946_89954082_RR OBD159_501 ACCCAGGTGGTATGACTCCAGAG
258 ORF166_14_89880613_89884758_89952946_89954082_RR OBD159_501 ACCCAGGTGGTATGACTCCAGAG
259 ORF169_1_206307932_206310423_206383244_206385305_FF OBD159_505 GAGGCTCAGGCAACATCCTACTTTCA
260 ORF169_1_206307932_206310423_206383244_206385305_FF OBD159_505 GAGGCTCAGGCAACATCCTACTTTCA
261 ORF17_1_76086337_76098934_76123667_76127663_FF OBD159_509 CTTTACTGGTGTCTTTTATGAACAA
262 ORF17_1_76086337_76098934_76123667_76127663_FF OBD159_509 CTTTACTGGTGTCTTTTATGAACAA
263 ORF17_11_128975846_128978309_129021767_129026895_FR OBD159_513 GCTGGTCTTGAACTCCTGGCTTC
264 ORF17_11_128975846_128978309_129021767_129026895_FR OBD159_513 GCTGGTCTTGAACTCCTGGCTTC
265 ORF17_2_78763526_78765449_78792347_78798562_FF OBD159_517 GATTTCTCAGTTTACATAGTTCAAA
266 ORF17_2_78763526_78765449_78792347_78798562_FF OBD159_517 GATTTCTCAGTTTACATAGTTCAAA
267 ORF17_21_17393292_17394472_17434190_17435748_RR OBD159_521 TACCAGGGCTGAGGGTGTTGTCCTAT
268 ORF17_21_17393292_17394472_17434190_17435748_RR OBD159_521 TACCAGGGCTGAGGGTGTTGTCCTAT
269 ORF17_4_37859966_37862832_37927829_37933173_FF OBD159_525 ACCTAAATAGTTATGAACAGTTTC
270 ORF17_4_37859966_37862832_37927829_37933173_FF OBD159_525 ACCTAAATAGTTATGAACAGTTTC
271 ORF17_7_23187280_23192079_23219086_23222886_FR OBD159_529 AAGTCAAGGCGGCAGTGAGCCAC
272 ORF17_7_23187280_23192079_23219086_23222886_FR OBD159_529 AAGTCAAGGCGGCAGTGAGCCAC
273 ORF17_8_65560550_65562514_65630980_65632323_FR OBD159_533 CATTTCTCTGCTGCCATCTCGTGGAT
274 ORF17_8_65560550_65562514_65630980_65632323_FR OBD159_533 CATTTCTCTGCTGCCATCTCGTGGAT
275 ORF17_8_88542085_88553888_88592759_88597112_RF OBD159_537 ACCTGACCAAACTTGAATAAATCA
276 ORF17_8_88542085_88553888_88592759_88597112_RF OBD159_537 ACCTGACCAAACTTGAATAAATCA
277 ORF170_2_56323476_56329636_56390760_56394124_FF OBD159_541 CTGGAGAGGAGGAGTCTTGTTTGCTT
278 ORF170_2_56323476_56329636_56390760_56394124_FF OBD159_541 CTGGAGAGGAGGAGTCTTGTTTGCTT
279 ORF171_3_63280859_63282281_63308360_63313318_FR OBD159_545 AACTATTTTCACATCATCTTGTAAG
280 ORF171_3_63280859_63282281_63308360_63313318_FR OBD159_545 AACTATTTTCACATCATCTTGTAAG
281 ORF171_8_27764811_27768513_27798255_27800731_RF OBD159_549 GGTGTGGAATACAATCTGATGGTTTC
282 ORF171_8_27764811_27768513_27798255_27800731_RF OBD159_549 GGTGTGGAATACAATCTGATGGTTTC
283 ORF173_8_113409304_113413871_113438847_113446082_FF OBD159_553 AGTTCTCAACCTGTGGGATGTATTAT
284 ORF173_8_113409304_113413871_113438847_113446082_FF OBD159_553 AGTTCTCAACCTGTGGGATGTATTAT
285 ORF176_12_96187243_96188661_96237099_96241349_RF OBD159_557 GGCTTTATGCCTGGGTCAGTTCTCCT
286 ORF176_12_96187243_96188661_96237099_96241349_RF OBD159_557 GGCTTTATGCCTGGGTCAGTTCTCCT
表1.d7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
213 OBD159_419 TTATGCCCCACCTTCTTCAGGGTAAT OBD159_417_419 -0.00076144
214 OBD159_419 TTATGCCCCACCTTCTTCAGGGTAAT OBD159_417_419 -0.00076144
215 OBD159_423 CCAGGATAACAGCAATGCCTACTTCC OBD159_421_423 -0.001555895
216 OBD159_423 CCAGGATAACAGCAATGCCTACTTCC OBD159_421_423 -0.001555895
217 OBD159_427 ATTACCTCACCCTTCCTCCTGTGCTG OBD159_425_427 -0.002923934
218 OBD159_427 ATTACCTCACCCTTCCTCCTGTGCTG OBD159_425_427 -0.002923934
219 OBD159_431 TTGAATGGTGAGGTGCCTTGTTAT OBD159_429_431 -0.000485603
220 OBD159_431 TTGAATGGTGAGGTGCCTTGTTAT OBD159_429_431 -0.000485603
221 OBD159_435 AAGAAAACGAAGGAAGGAAGATTC OBD159_433_435 -0.00351129
222 OBD159_435 AAGAAAACGAAGGAAGGAAGATTC OBD159_433_435 -0.00351129
223 OBD159_439 TTATAACAAAATATCATG OBD159_437_439 -0.002029871
224 OBD159_439 TTATAACAAAATATCATG OBD159_437_439 -0.002029871
225 OBD159_443 AAAACTCATTGCCAAACCCAAGGTCAT OBD159_441_443 -0.002006752
226 OBD159_443 AAAACTCATTGCCAAACCCAAGGTCAT OBD159_441_443 -0.002006752
227 OBD159_167 CCCCAACACAAACTGTCCTCAGGC OBD159_165_167 -0.005793058
228 OBD159_167 CCCCAACACAAACTGTCCTCAGGC OBD159_165_167 -0.005793058
229 OBD159_447 ATCAATGCCTGTGAACTATGAAAAGC OBD159_445_447 -0.002760872
230 OBD159_447 ATCAATGCCTGTGAACTATGAAAAGC OBD159_445_447 -0.002760872
231 OBD159_451 CCCTCCAACTGCTTGCCTATCCTTTG OBD159_449_451 -0.002333999
232 OBD159_451 CCCTCCAACTGCTTGCCTATCCTTTG OBD159_449_451 -0.002333999
233 OBD159_455 TCAAATGTCCAATACTGTCTATC OBD159_453_455 -0.001769071
234 OBD159_455 TCAAATGTCCAATACTGTCTATC OBD159_453_455 -0.001769071
235 OBD159_459 TCCCTTCTCCTGATTTTCCCTGTGGA OBD159_457_459 -0.002314144
236 OBD159_459 TCCCTTCTCCTGATTTTCCCTGTGGA OBD159_457_459 -0.002314144
237 OBD159_463 CTTCAAGTCTGTTTGCCTATTATTGC OBD159_461_463 -0.002502897
238 OBD159_463 CTTCAAGTCTGTTTGCCTATTATTGC OBD159_461_463 -0.002502897
239 OBD159_467 CCCTTTCTCCTCCTCTCTGCTCCTAT OBD159_465_467 -0.001657289
240 OBD159_467 CCCTTTCTCCTCCTCTCTGCTCCTAT OBD159_465_467 -0.001657289
241 OBD159_471 GCTCCAGCACCGTATTTCGCCTG OBD159_469_471 -0.001827556
242 OBD159_471 GCTCCAGCACCGTATTTCGCCTG OBD159_469_471 -0.001827556
243 OBD159_475 GAAGCAGAAGAAGGAGCAAGAAAG OBD159_473_475 -0.003164542
244 OBD159_475 GAAGCAGAAGAAGGAGCAAGAAAG OBD159_473_475 -0.003164542
245 OBD159_479 GCTTCAGTAAATACCGCCAAACG OBD159_477_479 -0.003908131
246 OBD159_479 GCTTCAGTAAATACCGCCAAACG OBD159_477_479 -0.003908131
247 OBD159_483 CTGAAAAGATGCTCTGCTACTGGGTG OBD159_481_483 -0.000935051
248 OBD159_483 CTGAAAAGATGCTCTGCTACTGGGTG OBD159_481_483 -0.000935051
249 OBD159_487 TATCGGAACGGTAACCAATCTCATTA OBD159_485_487 -0.002492994
250 OBD159_487 TATCGGAACGGTAACCAATCTCATTA OBD159_485_487 -0.002492994
251 OBD159_491 TGAAAGAGGCACCAGATGCGGAGGAA OBD159_489_491 -0.003044831
252 OBD159_491 TGAAAGAGGCACCAGATGCGGAGGAA OBD159_489_491 -0.003044831
253 OBD159_495 CCAACAACAATCTCCTTCCTCTCTAT OBD159_493_495 -0.000859479
254 OBD159_495 CCAACAACAATCTCCTTCCTCTCTAT OBD159_493_495 -0.000859479
255 OBD159_499 GCTGGGAGGGTCTTACACTGAGT OBD159_497_499 -0.002097728
256 OBD159_499 GCTGGGAGGGTCTTACACTGAGT OBD159_497_499 -0.002097728
257 OBD159_503 GGCAAGTTTCCTGCTCACCCCTG OBD159_501_503 -0.003841992
258 OBD159_503 GGCAAGTTTCCTGCTCACCCCTG OBD159_501_503 -0.003841992
259 OBD159_507 CTCTGAAGCCAAGCATAGATAGATGG OBD159_505_507 -0.003217459
260 OBD159_507 CTCTGAAGCCAAGCATAGATAGATGG OBD159_505_507 -0.003217459
261 OBD159_511 GAAGGTTCTGTCTTTATTTACAAT OBD159_509_511 -0.001863975
262 OBD159_511 GAAGGTTCTGTCTTTATTTACAAT OBD159_509_511 -0.001863975
263 OBD159_515 CGAGGTGGTAAAGTCAGCAAGTTA OBD159_513_515 -0.00204202
264 OBD159_515 CGAGGTGGTAAAGTCAGCAAGTTA OBD159_513_515 -0.00204202
265 OBD159_519 ATCTCTTAGTCTTAGCATCTATCA OBD159_517_519 -0.002864437
266 OBD159_519 ATCTCTTAGTCTTAGCATCTATCA OBD159_517_519 -0.002864437
267 OBD159_523 GGTATTGGCAACTAAAACGATTCCTC OBD159_521_523 -0.002896744
268 OBD159_523 GGTATTGGCAACTAAAACGATTCCTC OBD159_521_523 -0.002896744
269 OBD159_527 GGTGACAGACTGAGACTCCATTTA OBD159_525_527 -0.002960188
270 OBD159_527 GGTGACAGACTGAGACTCCATTTA OBD159_525_527 -0.002960188
271 OBD159_531 GCCTTCCACCAAGTCACAAAGAC OBD159_529_531 -0.003593697
272 OBD159_531 GCCTTCCACCAAGTCACAAAGAC OBD159_529_531 -0.003593697
273 OBD159_535 CAGTGACCACAGTTTCTGCCTCTG OBD159_533_535 -0.003278418
274 OBD159_535 CAGTGACCACAGTTTCTGCCTCTG OBD159_533_535 -0.003278418
275 OBD159_539 CATTTCATTCTACTGGATTCAGAT OBD159_537_539 -0.002009464
276 OBD159_539 CATTTCATTCTACTGGATTCAGAT OBD159_537_539 -0.002009464
277 OBD159_543 CTCACTAATGACATCCCACATCGCAG OBD159_541_543 -0.005427277
278 OBD159_543 CTCACTAATGACATCCCACATCGCAG OBD159_541_543 -0.005427277
279 OBD159_547 AGAAAGTCTCAAACAGAAGGCAAAT OBD159_545_547 -0.004238773
280 OBD159_547 AGAAAGTCTCAAACAGAAGGCAAAT OBD159_545_547 -0.004238773
281 OBD159_551 GGGTTAGTAGGAGAAATGTAAAACTC OBD159_549_551 -0.002929423
282 OBD159_551 GGGTTAGTAGGAGAAATGTAAAACTC OBD159_549_551 -0.002929423
283 OBD159_555 AAAGTGCTAAGTTTGTGAGGTGATAG OBD159_553_555 -0.003533315
284 OBD159_555 AAAGTGCTAAGTTTGTGAGGTGATAG OBD159_553_555 -0.003533315
285 OBD159_559 CCTAACACCTGCCAAGAAAGTGCTAA OBD159_557_559 -0.001914862
286 OBD159_559 CCTAACACCTGCCAAGAAAGTGCTAA OBD159_557_559 -0.001914862
表1.d8
   基因
213 rs2337406; rs11846409
214 rs2337406; rs11846409
215 MAGI1; rs145965284
216 MAGI1; rs145965284
217 MKLN1; rs114034759
218 MKLN1; rs114034759
219 CD109; SLC17A5
220 CD109; SLC17A5
221 MYOM1; rs751200138
222 MYOM1; rs751200138
223 LMBRD2; SKP2; rs2270909; rs12657634; rs10941274; rs12655052; rs3804446
224 LMBRD2; SKP2; rs2270909; rs12657634; rs10941274; rs12655052; rs3804446
225 CDH9; rs201058683
226 CDH9; rs201058683
227 LSM10; OSCP1
228 LSM10; OSCP1
229 MEIS1; rs11692361
230 MEIS1; rs11692361
231 BBX; rs11710737
232 BBX; rs11710737
233 GPM6A; rs1106568
234 GPM6A; rs1106568
235 rs12518614
236 rs12518614
237 ST18; rs7820212
238 ST18; rs7820212
239 PREX2; rs4512367
240 PREX2; rs4512367
241 ANKRD18A; CNTNAP3
242 ANKRD18A; CNTNAP3
243 NR2F1; rs587777277
244 NR2F1; rs587777277
245 FRMD6; GNG2; rs8015138
246 FRMD6; GNG2; rs8015138
247 GRM1; SHPRH
248 GRM1; SHPRH
249 ZNF790; ZNF850
250 ZNF790; ZNF850
251 GALNT2; rs4925506
252 GALNT2; rs4925506
253 ADCY1; rs1294908
254 ADCY1; rs1294908
255 FZD10; PIWIL1
256 FZD10; PIWIL1
257 EFCAB11; TDP1
258 EFCAB11; TDP1
259 SRGAP2; rs2987927
260 SRGAP2; rs2987927
261 ST6GALNAC3; rs915404
262 ST6GALNAC3; rs915404
263 ARHGAP32; rs11221522
264 ARHGAP32; rs11221522
265 REG3G
266 REG3G
267 CXADR
268 CXADR
269 GAFA3; PGM2; PTTG2; TBC1D1; rs17578878; rs35859249
270 GAFA3; PGM2; PTTG2; TBC1D1; rs17578878; rs35859249
271 NUPL2; rs858249
272 NUPL2; rs858249
273 ARMC1; rs6991838
274 ARMC1; rs6991838
275 rs10504861; rs7838490; rs7819570; rs11995572
276 rs10504861; rs7838490; rs7819570; rs11995572
277 CCDC85A; rs186920977; rs6747380; rs17268785
278 CCDC85A; rs186920977; rs6747380; rs17268785
279 SYNPR; rs13098482
280 SYNPR; rs13098482
281 CCDC25; ESCO2; rs80359869; rs80359844; rs80359845; rs80359846; rs80359847; rs80359848; rs80359849; rs80359850; rs80359851; rs80359852; rs80359853; rs80359854; rs80359855; rs80359856; rs80359857; rs797045565; rs797045566; rs80359858; rs80359859; rs80359861; rs80359862; rs146312522; rs80359863; rs80359864; rs80359865; rs80359866; rs80359867; rs80359868
282 CCDC25; ESCO2; rs80359869; rs80359844; rs80359845; rs80359846; rs80359847; rs80359848; rs80359849; rs80359850; rs80359851; rs80359852; rs80359853; rs80359854; rs80359855; rs80359856; rs80359857; rs797045565; rs797045566; rs80359858; rs80359859; rs80359861; rs80359862; rs146312522; rs80359863; rs80359864; rs80359865; rs80359866; rs80359867; rs80359868
283 CSMD3; rs189590409
284 CSMD3; rs189590409
285 CDK17; ELK3; rs4762284
286 CDK17; ELK3; rs4762284
表1.d9
   探針 基因座
287 ORF176_6_70049970_70053583_70128487_70130693_RR COL19A1; rs771562232
288 ORF176_6_70049970_70053583_70128487_70130693_RR COL19A1; rs771562232
289 ORF177_4_175618295_175622237_175657671_175665421_FF GPM6A; rs13144140
290 ORF177_4_175618295_175622237_175657671_175665421_FF GPM6A; rs13144140
291 ORF178_6_157189218_157193153_157237058_157240060_FF ARID1B; rs1057518918; rs1057518691; rs773740590; rs886044620; rs797044859; rs879253746; rs797045278; rs1057518984; rs797045279; rs797045280; rs797045281; rs797045282; rs886041706; rs797045283; rs9406316
292 ORF178_6_157189218_157193153_157237058_157240060_FF ARID1B; rs1057518918; rs1057518691; rs773740590; rs886044620; rs797044859; rs879253746; rs797045278; rs1057518984; rs797045279; rs797045280; rs797045281; rs797045282; rs886041706; rs797045283; rs9406316
293 ORF179_6_151443530_151449164_151503790_151504867_FR C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256
294 ORF179_6_151443530_151449164_151503790_151504867_FR C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256
295 ORF179_X_110436218_110442213_110470734_110476806_FF AMMECR1; RGAG1; rs1573036
296 ORF179_X_110436218_110442213_110470734_110476806_FF AMMECR1; RGAG1; rs1573036
297 ORF18_12_75093036_75104058_75141366_75143140_RF CAPS2; KCNC2
298 ORF18_12_75093036_75104058_75141366_75143140_RF CAPS2; KCNC2
299 ORF18_2_20303337_20304942_20340862_20341927_FR PUM2; rs111612372
300 ORF18_2_20303337_20304942_20340862_20341927_FR PUM2; rs111612372
301 ORF18_3_107703592_107708851_107736901_107739665_RR BBX; rs11710737
302 ORF18_3_107703592_107708851_107736901_107739665_RR BBX; rs11710737
303 ORF18_4_37845589_37847420_37859966_37862832_RF GAFA3; PGM2
304 ORF18_4_37845589_37847420_37859966_37862832_RF GAFA3; PGM2
305 ORF18_4_37845589_37847420_37862832_37864637_RR GAFA3; PGM2
306 ORF18_4_37845589_37847420_37862832_37864637_RR GAFA3; PGM2
307 ORF18_8_22370928_22373682_22443319_22445881_FF PIWIL2; PPP3CC; SLC39A14; rs879253763; rs879253764; rs879253765; rs1039778197; rs879253766; rs750281602; rs7833266; rs2272080
308 ORF18_8_22370928_22373682_22443319_22445881_FF PIWIL2; PPP3CC; SLC39A14; rs879253763; rs879253764; rs879253765; rs1039778197; rs879253766; rs750281602; rs7833266; rs2272080
309 ORF18_9_38681931_38686861_38768696_38769724_FF ANKRD18A; CNTNAP3
310 ORF18_9_38681931_38686861_38768696_38769724_FF ANKRD18A; CNTNAP3
311 ORF18_X_130743981_130757818_130793708_130805512_RR ARHGAP36; ENOX2
312 ORF18_X_130743981_130757818_130793708_130805512_RR ARHGAP36; ENOX2
313 ORF180_2_195583610_195589061_195640867_195645128_FR DNAH7; SLC39A10
314 ORF180_2_195583610_195589061_195640867_195645128_FR DNAH7; SLC39A10
315 ORF181_2_129231919_129233302_129249318_129258610_FF rs7567687; rs1660895
316 ORF181_2_129231919_129233302_129249318_129258610_FF rs7567687; rs1660895
317 ORF182_7_28717278_28719857_28738396_28739641_RF CREB5; rs56388170
318 ORF182_7_28717278_28719857_28738396_28739641_RF CREB5; rs56388170
319 ORF185_18_58155952_58157838_58215328_58217936_RF NEDD4L; rs4149601
320 ORF185_18_58155952_58157838_58215328_58217936_RF NEDD4L; rs4149601
321 ORF185_4_82581680_82585686_82618801_82621987_FR rs13138355; rs72909131
322 ORF185_4_82581680_82585686_82618801_82621987_FR rs13138355; rs72909131
323 ORF185_6_151443530_151449164_151537463_151538576_FR C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256; rs9479055; rs6931664
324 ORF185_6_151443530_151449164_151537463_151538576_FR C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256; rs9479055; rs6931664
325 ORF185_9_131590628_131592768_131652374_131654389_FF RAPGEF1; rs4740283; rs11243444
326 ORF185_9_131590628_131592768_131652374_131654389_FF RAPGEF1; rs4740283; rs11243444
327 ORF187_9_28314155_28333777_28367003_28368817_FR LINGO2; rs10812774
328 ORF187_9_28314155_28333777_28367003_28368817_FR LINGO2; rs10812774
329 ORF188_2_209095320_209098567_209157796_209164211_RR MAP2; PTH2R
330 ORF188_2_209095320_209098567_209157796_209164211_RR MAP2; PTH2R
331 ORF19_2_78765449_78768597_78804372_78809080_RF REG3G
332 ORF19_2_78765449_78768597_78804372_78809080_RF REG3G
333 ORF19_3_107708851_107713617_107779656_107783232_FF BBX; rs670752; rs11710737; rs6437740
334 ORF19_3_107708851_107713617_107779656_107783232_FF BBX; rs670752; rs11710737; rs6437740
335 ORF19_3_24254159_24259126_24306563_24314015_FF THRB; rs1505297; rs826230; rs826231; rs862247; rs826236; rs826238; rs826240; rs1868575; rs113700287; rs1158265; rs9830674; rs2167115; rs1505307; rs1505283; rs12485694; rs869785; rs869784; rs9310736; rs7622481
336 ORF19_3_24254159_24259126_24306563_24314015_FF THRB; rs1505297; rs826230; rs826231; rs862247; rs826236; rs826238; rs826240; rs1868575; rs113700287; rs1158265; rs9830674; rs2167115; rs1505307; rs1505283; rs12485694; rs869785; rs869784; rs9310736; rs7622481
337 ORF19_6_169185535_169187937_169230654_169232256_FR THBS2; rs9406328
338 ORF19_6_169185535_169187937_169230654_169232256_FR THBS2; rs9406328
339 ORF19_8_65560550_65562514_65628655_65630980_FF ARMC1; rs6991838
340 ORF19_8_65560550_65562514_65628655_65630980_FF ARMC1; rs6991838
341 ORF19_8_89905359_89910373_89958362_89963906_FR NBN; OSGIN2; rs121908973; rs10464867; rs14448; rs13312986; rs1063054; rs2735383; rs142301194; rs1057517262; rs756363734; rs786204181; rs1064795816; rs730881864; rs730881857; rs786201965; rs775397477; rs1057517075; rs786203223; rs786203920; rs1057516869; rs1061302; rs1057516852; rs587782653; rs1057516668; rs587782545; rs1060503466; rs1377580273; rs1057516611; rs61753717; rs864622143; rs786201745; rs749918573; rs766044684; rs1060503481; rs776417262; rs1057516332; rs1060503480; rs587782344; rs759232053; rs786203180; rs587782130; rs864622333; rs876659666; rs730881850; rs1060503467; rs709816; rs746965070; rs587781969; rs1057519588; rs1057517102; rs1057517209; rs121908974; rs876660290; rs767215758; rs876659521
342 ORF19_8_89905359_89910373_89958362_89963906_FR NBN; OSGIN2; rs121908973; rs10464867; rs14448; rs13312986; rs1063054; rs2735383; rs142301194; rs1057517262; rs756363734; rs786204181; rs1064795816; rs730881864; rs730881857; rs786201965; rs775397477; rs1057517075; rs786203223; rs786203920; rs1057516869; rs1061302; rs1057516852; rs587782653; rs1057516668; rs587782545; rs1060503466; rs1377580273; rs1057516611; rs61753717; rs864622143; rs786201745; rs749918573; rs766044684; rs1060503481; rs776417262; rs1057516332; rs1060503480; rs587782344; rs759232053; rs786203180; rs587782130; rs864622333; rs876659666; rs730881850; rs1060503467; rs709816; rs746965070; rs587781969; rs1057519588; rs1057517102; rs1057517209; rs121908974; rs876660290; rs767215758; rs876659521
343 ORF19_9_38681931_38686861_38760727_38762491_FR ANKRD18A; CNTNAP3
344 ORF19_9_38681931_38686861_38760727_38762491_FR ANKRD18A; CNTNAP3
345 ORF190_6_70118659_70128487_70187099_70190406_RF COL19A1; rs658805; rs771562232
346 ORF190_6_70118659_70128487_70187099_70190406_RF COL19A1; rs658805; rs771562232
347 ORF191_10_31830982_31838036_31880198_31881483_FF ARHGAP12; rs211257
348 ORF191_10_31830982_31838036_31880198_31881483_FF ARHGAP12; rs211257
349 ORF191_2_72535662_72545373_72613114_72619302_FR EXOC6B; rs2421095
350 ORF191_2_72535662_72545373_72613114_72619302_FR EXOC6B; rs2421095
351 ORF194_3_24254159_24259126_24306563_24314015_FF THRB; rs1505297; rs826230; rs826231; rs862247; rs826236; rs826238; rs826240; rs1868575; rs113700287; rs1158265; rs9830674; rs2167115; rs1505307; rs1505283; rs12485694; rs869785; rs869784; rs9310736; rs7622481
352 ORF194_3_24254159_24259126_24306563_24314015_FF THRB; rs1505297; rs826230; rs826231; rs862247; rs826236; rs826238; rs826240; rs1868575; rs113700287; rs1158265; rs9830674; rs2167115; rs1505307; rs1505283; rs12485694; rs869785; rs869784; rs9310736; rs7622481
353 ORF194_5_24638174_24644400_24709728_24712840_RF CDH10
354 ORF194_5_24638174_24644400_24709728_24712840_RF CDH10
355 ORF194_X_46916544_46918054_46983732_46995250_RR JADE3; RP2
356 ORF194_X_46916544_46918054_46983732_46995250_RR JADE3; RP2
357 ORF197_19_44168555_44170532_44257710_44261871_RR ZNF226; ZNF227; ZNF233; ZNF234; ZNF235
358 ORF197_19_44168555_44170532_44257710_44261871_RR ZNF226; ZNF227; ZNF233; ZNF234; ZNF235
359 ORF198_7_7793942_7796470_7867790_7872166_RR rs17137412; rs37972
360 ORF198_7_7793942_7796470_7867790_7872166_RR rs17137412; rs37972
表1.e1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
287 18 3; 3 0.026589963; 0.031898647
288 18 3; 3 0.026589963; 0.031898647
289 68 3; 4 0.224345313; 0.163371308
290 68 3; 4 0.224345313; 0.163371308
291 73 1; 1 0.162201186; 0.138576645
292 73 1; 1 0.162201186; 0.138576645
293 63; 46; 75 3; 5; 2; 4; 3; 5 0.216848517; 0.076682692; 0.273777277; 0.084172061; 0.228845362; 0.1125292
294 63; 46; 75 3; 5; 2; 4; 3; 5 0.216848517; 0.076682692; 0.273777277; 0.084172061; 0.228845362; 0.1125292
295 8; 8 1; 1; 1; 1 0.236185646; 0.249326315; 0.236185646; 0.249326315
296 8; 8 1; 1; 1; 1 0.236185646; 0.249326315; 0.236185646; 0.249326315
297 13; 13 4; 4; 4; 4 0.001148684; 0.001517434; 0.001148684; 0.001517434
298 13; 13 4; 4; 4; 4 0.001148684; 0.001517434; 0.001148684; 0.001517434
299 54 5; 6 0.040491239; 0.018151611
300 54 5; 6 0.040491239; 0.018151611
301 30 4; 5 0.022454364; 0.006393518
302 30 4; 5 0.022454364; 0.006393518
303 37; 37 5; 8; 5; 8 0.010942367; 0.000107113; 0.010942367; 0.000107113
304 37; 37 5; 8; 5; 8 0.010942367; 0.000107113; 0.010942367; 0.000107113
305 37; 37 5; 8; 5; 8 0.010942367; 0.000107113; 0.010942367; 0.000107113
306 37; 37 5; 8; 5; 8 0.010942367; 0.000107113; 0.010942367; 0.000107113
307 52; 32; 49 2; 2; 1; 2; 2; 2 0.276304155; 0.273929087; 0.363856051; 0.242145801; 0.276096976; 0.276409079
308 52; 32; 49 2; 2; 1; 2; 2; 2 0.276304155; 0.273929087; 0.363856051; 0.242145801; 0.276096976; 0.27640907
309 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
310 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
311 9; 34 1; 2; 1; 2 0.255358235; 0.047199169; 0.357029649; 0.251319324
312 9; 34 1; 2; 1; 2 0.255358235; 0.047199169; 0.357029649; 0.251319324
313 61; 81 2; 3; 3; 3 0.26657373; 0.222001213; 0.227770757; 0.222648484
314 61; 81 2; 3; 3; 3 0.26657373; 0.222001213; 0.227770757; 0.222648484
315 NA NA NA
316 NA NA NA
317 54 3; 3 0.193670022; 0.206710786
318 54 3; 3 0.193670022; 0.206710786
319 33 4; 2 0.029769861; 0.246924146
320 33 4; 2 0.029769861; 0.246924146
321 NA NA NA
322 NA NA NA
323 63; 46; 75 3; 5; 2; 4; 3; 5 0.216848517; 0.076682692; 0.273777277; 0.084172061; 0.228845362; 0.1125292
324 63; 46; 75 3; 5; 2; 4; 3; 5 0.216848517; 0.076682692; 0.273777277; 0.084172061; 0.228845362; 0.1125292
325 65 2; 2 0.258408092; 0.245566966
326 65 2; 2 0.258408092; 0.245566966
327 20 6; 4 7.69e-05; 0.007618647
328 20 6; 4 7.69e-05; 0.007618647
329 60; 1 5; 7; 1; 1 0.05512946; 0.009185497; 0.038988153; 0.042102538
330 60; 1 5; 7; 1; 1 0.05512946; 0.009185497; 0.038988153; 0.042102538
331 3 3; 2 0; 0.001770535
332 3 3; 2 0; 0.001770535
333 30 4; 5 0.022454364; 0.006393518
334 30 4; 5 0.022454364; 0.006393518
335 14 3; 2 0.013899641; 0.096260668
336 14 3; 2 0.013899641; 0.096260668
337 46 2; 3 0.273777277; 0.178397403
338 46 2; 3 0.273777277; 0.178397403
339 48 5; 4 0.02780594; 0.092112824
340 48 5; 4 0.02780594; 0.092112824
341 11; 14 1; 1; 1; 2 0.288260522; 0.301350316; 0.325643034; 0.096260668
342 11; 14 1; 1; 1; 2 0.288260522; 0.301350316; 0.325643034; 0.096260668
343 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
344 21; 8 8; 8; 8; 8 6.3e-07; 1.12e-06; 5.16e-12; 9.55e-12
345 18 3; 3 0.026589963; 0.031898647
346 18 3; 3 0.026589963; 0.031898647
347 12 1; 1 0.302214299; 0.314913912
348 12 1; 1 0.302214299; 0.314913912
349 20 1; 1 0.366490901; 0.372098641
350 20 1; 1 0.366490901; 0.372098641
351 14 3; 2 0.013899641; 0.096260668
352 14 3; 2 0.013899641; 0.096260668
353 13 1; 1 0.314642613; 0.32680192
354 13 1; 1 0.314642613; 0.32680192
355 17; 3 1; 1; 1; 1 0.350975055; 0.359834557; 0.108032075; 0.115907508
356 17; 3 1; 1; 1; 1 0.350975055; 0.359834557; 0.108032075; 0.115907508
357 7; 10; 10; 4; 10 1; 1; 1; 1; 1; 1; 1; 1; 1; 1 0.215038813; 0.227740664; 0.272678156; 0.285987033; 0.272678156; 0.285987033; 0.138432982; 0.14804367; 0.272678156; 0.285987033
358 7; 10; 10; 4; 10 1; 1; 1; 1; 1; 1; 1; 1; 1; 1 0.215038813; 0.227740664; 0.272678156; 0.285987033; 0.272678156; 0.285987033; 0.138432982; 0.14804367; 0.272678156; 0.285987033
359 NA NA NA
360 NA NA NA
表1.e2
   FDR_HyperG Percent_Sig logFC AveExpr
287 0.375519541; 0.376115439 16.67; 16.67 0.743060399 0.743060399
288 0.375519541; 0.376115439 16.67; 16.67 0.69286775 0.69286775
289 0.375519541; 0.376115439 4.41; 5.88 0.572881601 0.572881601
290 0.375519541; 0.376115439 4.41; 5.88 0.554041986 0.554041986
291 0.375519541; 0.376115439 1.37; 1.37 0.847472811 0.847472811
292 0.375519541; 0.376115439 1.37; 1.37 0.826205454 0.826205454
293 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 7.94; 4.35; 8.7; 4; 6.67 0.546916456 0.546916456
294 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 7.94; 4.35; 8.7; 4; 6.67 0.535096369 0.535096369
295 0.375519541; 0.376115439; 0.375519541; 0.376115439 12.5; 12.5; 12.5; 12.5 0.676303004 0.676303004
296 0.375519541; 0.376115439; 0.375519541; 0.376115439 12.5; 12.5; 12.5; 12.5 0.533842136 0.533842136
297 0.069549998; 0.082088441; 0.069549998; 0.082088441 30.77; 30.77; 30.77; 30.77 0.608450973 0.608450973
298 0.069549998; 0.082088441; 0.069549998; 0.082088441 30.77; 30.77; 30.77; 30.77 0.52321187 0.52321187
299 0.375519541; 0.376115439 9.26; 11.11 0.843438189 0.843438189
300 0.375519541; 0.376115439 9.26; 11.11 0.825036898 0.825036898
301 0.375519541; 0.217379602 13.33; 16.67 0.519816137 0.519816137
302 0.375519541; 0.217379602 13.33; 16.67 0.518513646 0.518513646
303 0.357678624; 0.013656923; 0.357678624; 0.013656923 13.51; 21.62; 13.51; 21.62 0.616631247 0.616631247
304 0.357678624; 0.013656923; 0.357678624; 0.013656923 13.51; 21.62; 13.51; 21.62 0.578396959 0.578396959
305 0.357678624; 0.013656923; 0.357678624; 0.013656923 13.51; 21.62; 13.51; 21.62 0.791519135 0.791519135
306 0.357678624; 0.013656923; 0.357678624; 0.013656923 13.51; 21.62; 13.51; 21.62 0.69245514 0.69245514
307 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.85; 3.85; 3.12; 6.25; 4.08; 4.08 0.701431344 0.701431344
308 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.85; 3.85; 3.12; 6.25; 4.08; 4.08 0.658724646 0.658724646
309 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.694869829 0.694869829
310 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.571266171 0.571266171
311 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 22.22; 2.94; 5.88 0.682462284 0.682462284
312 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 22.22; 2.94; 5.88 0.609898655 0.609898655
313 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.28; 4.92; 3.7; 3.7 0.875323772 0.875323772
314 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.28; 4.92; 3.7; 3.7 0.803435131 0.803435131
315 NA NA 0.593346815 0.593346815
316 NA NA 0.499638042 0.499638042
317 0.375519541; 0.376115439 5.56; 5.56 0.934419976 0.934419976
318 0.375519541; 0.376115439 5.56; 5.56 0.841538744 0.841538744
319 0.375519541; 0.376115439 12.12; 6.06 0.6441859 0.6441859
320 0.375519541; 0.376115439 12.12; 6.06 0.589681807 0.589681807
321 NA NA 0.698803831 0.698803831
322 NA NA 0.561454343 0.561454343
323 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 7.94; 4.35; 8.7; 4; 6.67 0.506604445 0.506604445
324 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 7.94; 4.35; 8.7; 4; 6.67 0.494121362 0.494121362
325 0.375519541; 0.376115439 3.08; 3.08 0.731953563 0.731953563
326 0.375519541; 0.376115439 3.08; 3.08 0.654724778 0.654724778
327 0.008046243; 0.242844385 30; 20 0.843775275 0.843775275
328 0.008046243; 0.242844385 30; 20 0.684458116 0.684458116
329 0.375519541; 0.275564898; 0.375519541; 0.376115439 8.33; 11.67; 100; 100 0.870854788 0.870854788
330 0.375519541; 0.275564898; 0.375519541; 0.376115439 8.33; 11.67; 100; 100 0.686466545 0.686466545
331 0; 0.082088441 100; 100 0.534288724 0.534288724
332 0; 0.082088441 100; 100 0.519928663 0.519928663
333 0.375519541; 0.217379602 13.33; 16.67 0.610561918 0.610561918
334 0.375519541; 0.217379602 13.33; 16.67 0.564884491 0.564884491
335 0.375519541; 0.376115439 21.43; 14.29 0.574528501 0.574528501
336 0.375519541; 0.376115439 21.43; 14.29 0.53282889 0.53282889
337 0.375519541; 0.376115439 4.35; 6.52 0.796010876 0.796010876
338 0.375519541; 0.376115439 4.35; 6.52 0.739967602 0.739967602
339 0.375519541; 0.376115439 10.42; 8.33 0.516922094 0.516922094
340 0.375519541; 0.376115439 10.42; 8.33 0.515009153 0.515009153
341 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.09; 9.09; 7.14; 14.29 0.537064279 0.537064279
342 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.09; 9.09; 7.14; 14.29 0.534110975 0.534110975
343 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.688184297 0.688184297
344 0.000109745; 0.00028483; 1.35e-09; 4.87e-09 38.1; 38.1; 100; 100 0.561280923 0.561280923
345 0.375519541; 0.376115439 16.67; 16.67 0.6396234 0.6396234
346 0.375519541; 0.376115439 16.67; 16.67 0.62977534 0.62977534
347 0.375519541; 0.376115439 8.33; 8.33 0.797414414 0.797414414
348 0.375519541; 0.376115439 8.33; 8.33 0.712359797 0.712359797
349 0.375519541; 0.376115439 5; 5 0.575759347 0.575759347
350 0.375519541; 0.376115439 5; 5 0.49258676 0.49258676
351 0.375519541; 0.376115439 21.43; 14.29 0.565428207 0.565428207
352 0.375519541; 0.376115439 21.43; 14.29 0.529609408 0.529609408
353 0.375519541; 0.376115439 7.69; 7.69 0.554546607 0.554546607
354 0.375519541; 0.376115439 7.69; 7.69 0.528816642 0.528816642
355 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 5.88; 33.33; 33.33 0.703969549 0.703969549
356 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 5.88; 33.33; 33.33 0.676506328 0.676506328
357 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 14.29; 14.29; 10; 10; 10; 10; 25; 25; 10; 10 0.688148639 0.688148639
358 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 14.29; 14.29; 10; 10; 10; 10; 25; 25; 10; 10 0.659914521 0.659914521
359 NA NA 0.671202878 0.671202878
360 NA NA 0.575613955 0.575613955
表1.e3
   t P值 adj.P.Val B FC FC_1 LS
287 14.79804494 0.00000000485 0.00000387 11.28467862 1.673722555 1.673722555 1
288 17.82482686 0.000000000545 0.000000726 13.3989763 1.616493549 1.616493549 1
289 12.91122911 0.0000000226 0.00000847 9.814824696 1.487491682 1.487491682 1
290 11.21353517 0.000000104 0.00001 8.301902675 1.468193363 1.468193363 1
291 12.15769748 0.0000000442 0.000012 9.162175379 1.799346224 1.799346224 1
292 7.763755476 0.00000515 0.000113029 4.321223889 1.773015875 1.773015875 1
293 11.40568259 0.0000000895 0.0000173 8.468302773 1.460959775 1.460959775 1
294 8.861237956 0.00000132 0.0000474 5.724536025 1.449038944 1.449038944 1
295 9.499895126 0.000000629 0.0000299 6.478297904 1.598039428 1.598039428 1
296 5.637118565 0.000111697 0.001574022 1.229130688 1.447779744 1.447779744 1
297 12.54327613 0.0000000312 0.00000985 9.501226666 1.524621338 1.524621338 1
298 19.75351316 0.000000000165 0.000000477 14.48625207 1.437151217 1.437151217 1
299 20.82530404 0.0000000000891 0.00000039 15.03420497 1.794321224 1.794321224 1
300 12.16144032 0.000000044 0.000012 9.165519416 1.771580348 1.771580348 1
301 15.50410556 0.00000000272 0.00000148 11.88695557 1.43377251 1.43377251 1
302 11.43283696 0.0000000872 0.000017 8.4941417 1.432478659 1.432478659 1
303 8.091251762 0.00000346 0.000162025 4.791306687 1.5332907 1.5332907 1
304 8.889858739 0.00000127 0.0000463 5.759261158 1.49318918 1.49318918 1
305 13.0614879 0.0000000198 0.00000792 9.940188169 1.73089611 1.73089611 1
306 10.13449544 0.000000314 0.0000195 7.185647609 1.616031299 1.616031299 1
307 17.12053769 0.000000000868 0.000000895 12.96563906 1.626117316 1.626117316 1
308 11.67800798 0.000000069 0.0000149 8.724725184 1.578686435 1.578686435 1
309 5.377075419 0.000169218 0.002110359 0.802297875 1.618738371 1.618738371 1
310 6.099949932 0.0000537 0.00053451 1.899523005 1.485827024 1.485827024 1
311 10.21023183 0.00000029 0.0000186 7.267445548 1.604876502 1.604876502 1
312 7.117148255 0.0000125 0.000365074 3.475653858 1.526151997 1.526151997 1
313 17.54374798 0.000000000691 0.00000167 13.07787093 1.834419723 1.834419723 1
314 20.65930634 0.0000000000979 0.00000039 14.95175502 1.745251717 1.745251717 1
315 13.88146564 0.00000001 0.0000055 10.59810905 1.508742726 1.508742726 1
316 5.926104266 0.0000701 0.000645984 1.62438742 1.413858794 1.413858794 1
317 11.34417863 0.0000000916 0.00000932 8.430204079 1.911122129 1.911122129 1
318 12.89386645 0.0000000229 0.00000857 9.80023923 1.791960385 1.791960385 1
319 8.682862194 0.00000167 0.000102493 5.532697246 1.562857131 1.562857131 1
320 10.89680686 0.000000143 0.0000122 7.984904648 1.504914795 1.504914795 1
321 5.568028354 0.000124615 0.001702064 1.116657177 1.62315844 1.62315844 1
322 4.050545041 0.001613641 0.006367669 -1.601006161 1.475756139 1.475756139 1
323 17.28762581 0.000000000819 0.0000018 12.92544124 1.420702465 1.420702465 1
324 10.55306209 0.000000202 0.0000151 7.63102272 1.408462704 1.408462704 1
325 13.01763676 0.0000000206 0.00000805 9.903761182 1.660886588 1.660886588 1
326 9.195548619 0.00000089 0.0000372 6.124544214 1.574315593 1.574315593 1
327 12.02519226 0.0000000499 0.0000126 9.043107691 1.794740517 1.794740517 1
328 13.3734662 0.0000000146 0.00000347 10.25629174 1.607098233 1.607098233 1
329 11.57704591 0.000000076 0.0000158 8.630357322 1.828746101 1.828746101 1
330 9.119712318 0.000000971 0.0000394 6.034870076 1.609337092 1.609337092 1
331 11.89618574 0.0000000541 0.00000692 8.957125961 1.448227974 1.448227974 1
332 9.888133631 0.000000423 0.0000439 6.921798706 1.433884345 1.433884345 1
333 10.93247539 0.000000142 0.0000229 8.008110873 1.52685379 1.52685379 1
334 7.477823387 0.00000752 0.000143556 3.931392434 1.479269067 1.479269067 1
335 12.4790638 0.0000000317 0.00000524 9.488168688 1.489190689 1.489190689 1
336 13.34668647 0.0000000156 0.00000697 10.17396116 1.446763284 1.446763284 1
337 6.818288352 0.000019 0.000483128 3.046799664 1.736293544 1.736293544 1
338 4.346150204 0.000954612 0.004295132 -1.065051949 1.670138332 1.670138332 1
339 9.051835894 0.00000105 0.0000413 5.954082233 1.430899249 1.430899249 1
340 6.535333442 0.0000286 0.000631898 2.62938138 1.429003206 1.429003206 1
341 12.02753101 0.0000000498 0.0000126 9.045220814 1.451016857 1.451016857 1
342 13.77879282 0.0000000104 0.00000291 10.58706514 1.448049555 1.448049555 1
343 5.570795634 0.000124068 0.001696213 1.121175096 1.611254399 1.611254399 1
344 5.819089703 0.0000827 0.000723642 1.452893167 1.475578755 1.475578755 1
345 10.99347808 0.000000129 0.0000114 8.082564002 1.557922427 1.557922427 1
346 7.291733847 0.00000988 0.00031393 3.720569026 1.547324022 1.547324022 1
347 16.34689112 0.00000000148 0.00000114 12.4647108 1.737983534 1.737983534 1
348 13.135413 0.0000000186 0.0000077 10.00130376 1.638481969 1.638481969 1
349 13.36085973 0.0000000154 0.00000694 10.18543862 1.490461745 1.490461745 1
350 6.954716167 0.0000154 0.00023183 3.190545206 1.406965312 1.406965312 1
351 12.60506746 0.0000000284 0.00000497 9.599712317 1.479826672 1.479826672 1
352 12.62371363 0.0000000291 0.00000947 9.570596966 1.443538322 1.443538322 1
353 14.39806455 0.00000000662 0.00000459 10.99110447 1.468706993 1.468706993 1
354 11.91678031 0.0000000531 0.00000684 8.976322614 1.442745311 1.442745311 1
355 9.495063948 0.000000652 0.000057 6.485669588 1.628980743 1.628980743 1
356 8.676700215 0.00000164 0.0000546 5.498436395 1.598264661 1.598264661 1
357 14.34994802 0.00000000687 0.00000467 10.95516949 1.611214575 1.611214575 1
358 10.42711402 0.000000231 0.0000162 7.498711132 1.579989008 1.579989008 1
359 8.231730658 0.0000029 0.000144892 4.971137159 1.592400111 1.592400111 1
360 14.99572789 0.00000000398 0.00000178 11.52107107 1.490311547 1.490311547 1
表1.e4
      探針序列 探針位置
偵測到之環 60 mer Chr
287 mHC AAAATCAGTTAATTGGAATTAATATAATTCGATTACTGAAGAGTCCATTAGAGTAAGCAG 6
288 sHC AAAATCAGTTAATTGGAATTAATATAATTCGATTACTGAAGAGTCCATTAGAGTAAGCAG 6
289 mHC CTAAGCAGAGACTAAGAATATCTTAAAGTCGATTTTATTTTTTTTTAAGGATCTGTTACA 4
290 sHC CTAAGCAGAGACTAAGAATATCTTAAAGTCGATTTTATTTTTTTTTAAGGATCTGTTACA 4
291 mHC TTTTATATGTTTAACAGAATAGTATATATCGAAACTGGTTTATGTATAAAATATTAGGAC 6
292 sHC TTTTATATGTTTAACAGAATAGTATATATCGAAACTGGTTTATGTATAAAATATTAGGAC 6
293 mHC GAGGCGGGTGATTCACAAGGTCAGATGTTCGATTTGGGTATATCTAATGTTTTCTCATGA 6
294 sHC GAGGCGGGTGATTCACAAGGTCAGATGTTCGATTTGGGTATATCTAATGTTTTCTCATGA 6
295 sHC GCTGATTGTTGCTATATTGGAATTTGGATCGAATTTATTGGCATATAATTGTTCATAGCA X
296 mHC GCTGATTGTTGCTATATTGGAATTTGGATCGAATTTATTGGCATATAATTGTTCATAGCA X
297 mHC AAGAATATCATCCTGGAAGTTAGGAAATTCGAGTAGCTATCTGTTTCTTCTATATCTAAA 12
298 sHC AAGAATATCATCCTGGAAGTTAGGAAATTCGAGTAGCTATCTGTTTCTTCTATATCTAAA 12
299 sHC TATATGGTACATATTATACATATTTCTATCGATCTCATTTGTCCATTTGCAAATGGAAAC 2
300 mHC TATATGGTACATATTATACATATTTCTATCGATCTCATTTGTCCATTTGCAAATGGAAAC 2
301 sHC TTGAAACTTTAACTCTGTCAAGATGTTATCGAAGGTATCAATATCTGTGTAGTTGTATGA 3
302 mHC TTGAAACTTTAACTCTGTCAAGATGTTATCGAAGGTATCAATATCTGTGTAGTTGTATGA 3
303 mHC CCTACCAGAACTCTTAAATCTATAATATTCGATTCTTGATTAAATAATCTTTTATTTTCA 4
304 sHC CCTACCAGAACTCTTAAATCTATAATATTCGATTCTTGATTAAATAATCTTTTATTTTCA 4
305 mHC TGAAAATAAAAGATTATTTAATCAAGAATCGATATATTCTACAAACTGCTTTATTGTAGA 4
306 sHC TGAAAATAAAAGATTATTTAATCAAGAATCGATATATTCTACAAACTGCTTTATTGTAGA 4
307 sHC TATAAGACAGTAATTTCAGAATTACTGTTCGATTAGCACTGATTTTGAATGTTTCAAAAG 8
308 mHC TATAAGACAGTAATTTCAGAATTACTGTTCGATTAGCACTGATTTTGAATGTTTCAAAAG 8
309 mHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGATACAGGTATGCAAGTTCTTATTTTTTGT 9
310 sHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGATACAGGTATGCAAGTTCTTATTTTTTGT 9
311 sHC ATTAAATATAACCTATTATCCTTATCACTCGAGAAAAGTCTGAACTAAATCTGTTAAGGT X
312 mHC ATTAAATATAACCTATTATCCTTATCACTCGAGAAAAGTCTGAACTAAATCTGTTAAGGT X
313 mHC ATTTTTAATTATTAAAAAATAATGTTTTTCGACAGGTTAAGGATAAAGAGAAAATATTAA 2
314 sHC ATTTTTAATTATTAAAAAATAATGTTTTTCGACAGGTTAAGGATAAAGAGAAAATATTAA 2
315 mHC AGGTAATTAAGACAAGAAAGACATTTATTCGATATACATTCTTTGTACTTATTGTTGATA 2
316 sHC AGGTAATTAAGACAAGAAAGACATTTATTCGATATACATTCTTTGTACTTATTGTTGATA 2
317 sHC GTCATAAAATATTACCAGAAAAGCATATTCGAACTCTTTATATTCTTTTATATTTTCATA 7
318 mHC GTCATAAAATATTACCAGAAAAGCATATTCGAACTCTTTATATTCTTTTATATTTTCATA 7
319 mHC CGTAATGTTATTTTTAAAAACGTACTTTTCGATGTCTAATGAGACAGTGGAATTCTACTT 18
320 sHC CGTAATGTTATTTTTAAAAACGTACTTTTCGATGTCTAATGAGACAGTGGAATTCTACTT 18
321 mHC AAGTTTTTTTTCGCTATAGTTACAGTACTCGAATTGGGTGATTTGAGTAGAGTTTAATCA 4
322 sHC AAGTTTTTTTTCGCTATAGTTACAGTACTCGAATTGGGTGATTTGAGTAGAGTTTAATCA 4
323 mHC GAGGCGGGTGATTCACAAGGTCAGATGTTCGATATCACAGAACTCATAAAAGTTAAAATG 6
324 sHC GAGGCGGGTGATTCACAAGGTCAGATGTTCGATATCACAGAACTCATAAAAGTTAAAATG 6
325 mHC TTTTAAATTTTTATTATGATTATTATTTTCGATTAATAAGATGTTTTCAGACACTGGAAC 9
326 sHC TTTTAAATTTTTATTATGATTATTATTTTCGATTAATAAGATGTTTTCAGACACTGGAAC 9
327 mHC AAAGTCATACAACTACTATGTAAGATATTCGATTTCCCACATGGAATATACAGATTTAGC 9
328 sHC AAAGTCATACAACTACTATGTAAGATATTCGATTTCCCACATGGAATATACAGATTTAGC 9
329 mHC ACAGAATTAAATTGTATGTCAAGTTACTTCGAAAGGTCTTTCTAGTGATACATTTAAACT 2
330 sHC ACAGAATTAAATTGTATGTCAAGTTACTTCGAAAGGTCTTTCTAGTGATACATTTAAACT 2
331 sHC AGATGATAAACAATGCATTTGGAATATATCGATTTTAAATTTATTCCTAATTTCTAAGGT 2
332 mHC AGATGATAAACAATGCATTTGGAATATATCGATTTTAAATTTATTCCTAATTTCTAAGGT 2
333 mHC TTACATTAAATAGCAATTAAAACATTTTTCGAAAACAAATAGATAAGATTTAATTGTAGT 3
334 sHC TTACATTAAATAGCAATTAAAACATTTTTCGAAAACAAATAGATAAGATTTAATTGTAGT 3
335 sHC AACTCTTCCATAAAGATTTATCAAAAATTCGAAAAGAAGAACAAGAAAAAGCCTAATTCC 3
336 mHC AACTCTTCCATAAAGATTTATCAAAAATTCGAAAAGAAGAACAAGAAAAAGCCTAATTCC 3
337 mHC TTAAAAAAGATTTAAAAAGTCAAAAGAGTCGAAGTTATTAAATTTCCATCTAAAATTCCA 6
338 sHC TTAAAAAAGATTTAAAAAGTCAAAAGAGTCGAAGTTATTAAATTTCCATCTAAAATTCCA 6
339 sHC TATCTCTATGTAATAATCACTAAAAGTATCGAAAATACTGTACAATAGTCTCAGGATTTG 8
340 mHC TATCTCTATGTAATAATCACTAAAAGTATCGAAAATACTGTACAATAGTCTCAGGATTTG 8
341 mHC ATGTATATTTTTCATCTAATATACAAAGTCGATGTTCACACAATGCCAAAATTGTGTAAG 8
342 sHC ATGTATATTTTTCATCTAATATACAAAGTCGATGTTCACACAATGCCAAAATTGTGTAAG 8
343 mHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGATTAGTGGTTATTTTATTTCTATAATTTC 9
344 sHC CCACGGAGGGGTCCTTCTGAACTGCAATTCGATTAGTGGTTATTTTATTTCTATAATTTC 9
345 sHC TGAAGGTTAGATTTTCTTAATAACATTTTCGAGTACTACTTTGAAGATAAGACATTTTGT 6
346 mHC TGAAGGTTAGATTTTCTTAATAACATTTTCGAGTACTACTTTGAAGATAAGACATTTTGT 6
347 sHC ATAAATAATGACAAGTTATTTTATGTAATCGAGACCCCTCAAAAGATATTTTCAGACTTT 10
348 mHC ATAAATAATGACAAGTTATTTTATGTAATCGAGACCCCTCAAAAGATATTTTCAGACTTT 10
349 mHC GAAGTATTTCATTTAAAAAAAAATCAAATCGATGTATTTTTTGACTTAATGATCAGTGTT 2
350 sHC GAAGTATTTCATTTAAAAAAAAATCAAATCGATGTATTTTTTGACTTAATGATCAGTGTT 2
351 sHC AACTCTTCCATAAAGATTTATCAAAAATTCGAAAAGAAGAACAAGAAAAAGCCTAATTCC 3
352 mHC AACTCTTCCATAAAGATTTATCAAAAATTCGAAAAGAAGAACAAGAAAAAGCCTAATTCC 3
353 mHC TGTAATATAATTTTTTCTTTGAGATTTCTCGATAGCAAGTACTTATGCCTATTCCCAAGT 5
354 sHC TGTAATATAATTTTTTCTTTGAGATTTCTCGATAGCAAGTACTTATGCCTATTCCCAAGT 5
355 mHC GTGGAGTTTATCTTAACCACTTTTACAATCGAATAAGTACTTCATTTGCTGTATGCCCTT X
356 sHC GTGGAGTTTATCTTAACCACTTTTACAATCGAATAAGTACTTCATTTGCTGTATGCCCTT X
357 mHC AATAATTTCTCAATACTCTAGAAAGATATCGACTTAGGTAAAAAACTTGACAAGAGACAA 19
358 sHC AATAATTTCTCAATACTCTAGAAAGATATCGACTTAGGTAAAAAACTTGACAAGAGACAA 19
359 mHC GTGATGAAACTTAAAAAAAAATTTTTTTTCGAATTTTAAAAAATGGTTAATTGCTTCTAG 7
360 sHC GTGATGAAACTTAAAAAAAAATTTTTTTTCGAATTTTAAAAAATGGTTAATTGCTTCTAG 7
表1.e5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
287 70049970 70050001 70128487 70128518 6 70049970 70053971 70128487 70132488
288 70049970 70050001 70128487 70128518 6 70049970 70053971 70128487 70132488
289 175622206 175622237 175665390 175665421 4 175618236 175622237 175661420 175665421
290 175622206 175622237 175665390 175665421 4 175618236 175622237 175661420 175665421
291 157193122 157193153 157240029 157240060 6 157189152 157193153 157236059 157240060
292 157193122 157193153 157240029 157240060 6 157189152 157193153 157236059 157240060
293 151449133 151449164 151503790 151503821 6 151445163 151449164 151503790 151507791
294 151449133 151449164 151503790 151503821 6 151445163 151449164 151503790 151507791
295 110442182 110442213 110476775 110476806 X 110438212 110442213 110472805 110476806
296 110442182 110442213 110476775 110476806 X 110438212 110442213 110472805 110476806
297 75093036 75093067 75143109 75143140 12 75093036 75097037 75139139 75143140
298 75093036 75093067 75143109 75143140 12 75093036 75097037 75139139 75143140
299 20304911 20304942 20340862 20340893 2 20300941 20304942 20340862 20344863
300 20304911 20304942 20340862 20340893 2 20300941 20304942 20340862 20344863
301 107703592 107703623 107736901 107736932 3 107703592 107707593 107736901 107740902
302 107703592 107703623 107736901 107736932 3 107703592 107707593 107736901 107740902
303 37845589 37845620 37862801 37862832 4 37845589 37849590 37858831 37862832
304 37845589 37845620 37862801 37862832 4 37845589 37849590 37858831 37862832
305 37845589 37845620 37862832 37862863 4 37845589 37849590 37862832 37866833
306 37845589 37845620 37862832 37862863 4 37845589 37849590 37862832 37866833
307 22373651 22373682 22445850 22445881 8 22369681 22373682 22441880 22445881
308 22373651 22373682 22445850 22445881 8 22369681 22373682 22441880 22445881
309 38686830 38686861 38769693 38769724 9 38682860 38686861 38765723 38769724
310 38686830 38686861 38769693 38769724 9 38682860 38686861 38765723 38769724
311 130743981 130744012 130793708 130793739 X 130743981 130747982 130793708 130797709
312 130743981 130744012 130793708 130793739 X 130743981 130747982 130793708 130797709
313 195589030 195589061 195640867 195640898 2 195585060 195589061 195640867 195644868
314 195589030 195589061 195640867 195640898 2 195585060 195589061 195640867 195644868
315 129233271 129233302 129258579 129258610 2 129229301 129233302 129254609 129258610
316 129233271 129233302 129258579 129258610 2 129229301 129233302 129254609 129258610
317 28717278 28717309 28739610 28739641 7 28717278 28721279 28735640 28739641
318 28717278 28717309 28739610 28739641 7 28717278 28721279 28735640 28739641
319 58155952 58155983 58217905 58217936 18 58155952 58159953 58213935 58217936
320 58155952 58155983 58217905 58217936 18 58155952 58159953 58213935 58217936
321 82585655 82585686 82618801 82618832 4 82581685 82585686 82618801 82622802
322 82585655 82585686 82618801 82618832 4 82581685 82585686 82618801 82622802
323 151449133 151449164 151537463 151537494 6 151445163 151449164 151537463 151541464
324 151449133 151449164 151537463 151537494 6 151445163 151449164 151537463 151541464
325 131592737 131592768 131654358 131654389 9 131588767 131592768 131650388 131654389
326 131592737 131592768 131654358 131654389 9 131588767 131592768 131650388 131654389
327 28333746 28333777 28367003 28367034 9 28329776 28333777 28367003 28371004
328 28333746 28333777 28367003 28367034 9 28329776 28333777 28367003 28371004
329 209095320 209095351 209157796 209157827 2 209095320 209099321 209157796 209161797
330 209095320 209095351 209157796 209157827 2 209095320 209099321 209157796 209161797
331 78765449 78765480 78809049 78809080 2 78765449 78769450 78805079 78809080
332 78765449 78765480 78809049 78809080 2 78765449 78769450 78805079 78809080
333 107713586 107713617 107783201 107783232 3 107709616 107713617 107779231 107783232
334 107713586 107713617 107783201 107783232 3 107709616 107713617 107779231 107783232
335 24259095 24259126 24313984 24314015 3 24255125 24259126 24310014 24314015
336 24259095 24259126 24313984 24314015 3 24255125 24259126 24310014 24314015
337 169187906 169187937 169230654 169230685 6 169183936 169187937 169230654 169234655
338 169187906 169187937 169230654 169230685 6 169183936 169187937 169230654 169234655
339 65562483 65562514 65630949 65630980 8 65558513 65562514 65626979 65630980
340 65562483 65562514 65630949 65630980 8 65558513 65562514 65626979 65630980
341 89910342 89910373 89958362 89958393 8 89906372 89910373 89958362 89962363
342 89910342 89910373 89958362 89958393 8 89906372 89910373 89958362 89962363
343 38686830 38686861 38760727 38760758 9 38682860 38686861 38760727 38764728
344 38686830 38686861 38760727 38760758 9 38682860 38686861 38760727 38764728
345 70118659 70118690 70190375 70190406 6 70118659 70122660 70186405 70190406
346 70118659 70118690 70190375 70190406 6 70118659 70122660 70186405 70190406
347 31838005 31838036 31881452 31881483 10 31834035 31838036 31877482 31881483
348 31838005 31838036 31881452 31881483 10 31834035 31838036 31877482 31881483
349 72545342 72545373 72613114 72613145 2 72541372 72545373 72613114 72617115
350 72545342 72545373 72613114 72613145 2 72541372 72545373 72613114 72617115
351 24259095 24259126 24313984 24314015 3 24255125 24259126 24310014 24314015
352 24259095 24259126 24313984 24314015 3 24255125 24259126 24310014 24314015
353 24638174 24638205 24712809 24712840 5 24638174 24642175 24708839 24712840
354 24638174 24638205 24712809 24712840 5 24638174 24642175 24708839 24712840
355 46916544 46916575 46983732 46983763 X 46916544 46920545 46983732 46987733
356 46916544 46916575 46983732 46983763 X 46916544 46920545 46983732 46987733
357 44168555 44168586 44257710 44257741 19 44168555 44172556 44257710 44261711
358 44168555 44168586 44257710 44257741 19 44168555 44172556 44257710 44261711
359 7793942 7793973 7867790 7867821 7 7793942 7797943 7867790 7871791
360 7793942 7793973 7867790 7867821 7 7793942 7797943 7867790 7871791
表1.e6
   探針 PCR- 引子 1_ID PCR_ 引子 1
287 ORF176_6_70049970_70053583_70128487_70130693_RR OBD159_561 TGGTTAGGTTCAAACTCAGGTAGCCT
288 ORF176_6_70049970_70053583_70128487_70130693_RR OBD159_561 TGGTTAGGTTCAAACTCAGGTAGCCT
289 ORF177_4_175618295_175622237_175657671_175665421_FF OBD159_565 AAGGCAGAGGATAAGATAGTGGTCTC
290 ORF177_4_175618295_175622237_175657671_175665421_FF OBD159_565 AAGGCAGAGGATAAGATAGTGGTCTC
291 ORF178_6_157189218_157193153_157237058_157240060_FF OBD159_569 GCCTTCCCTGCCTTCTTACTTCC
292 ORF178_6_157189218_157193153_157237058_157240060_FF OBD159_569 GCCTTCCCTGCCTTCTTACTTCC
293 ORF179_6_151443530_151449164_151503790_151504867_FR OBD159_573 CGCCTGTAACCCCAGCATTTTGG
294 ORF179_6_151443530_151449164_151503790_151504867_FR OBD159_573 CGCCTGTAACCCCAGCATTTTGG
295 ORF179_X_110436218_110442213_110470734_110476806_FF OBD159_577 ACAGGGACTGAGCAGGTCGCTGAAAA
296 ORF179_X_110436218_110442213_110470734_110476806_FF OBD159_577 ACAGGGACTGAGCAGGTCGCTGAAAA
297 ORF18_12_75093036_75104058_75141366_75143140_RF OBD159_581 ATCCTCAGAATGGGTCCGTCTCAGAG
298 ORF18_12_75093036_75104058_75141366_75143140_RF OBD159_581 ATCCTCAGAATGGGTCCGTCTCAGAG
299 ORF18_2_20303337_20304942_20340862_20341927_FR OBD159_585 CAGCACAGTGGAGTGGTCGTGAC
300 ORF18_2_20303337_20304942_20340862_20341927_FR OBD159_585 CAGCACAGTGGAGTGGTCGTGAC
301 ORF18_3_107703592_107708851_107736901_107739665_RR OBD159_589 GATAAAAGCCCTACAAGTGCTAATCA
302 ORF18_3_107703592_107708851_107736901_107739665_RR OBD159_589 GATAAAAGCCCTACAAGTGCTAATCA
303 ORF18_4_37845589_37847420_37859966_37862832_RF OBD159_593 CTTACAGCCTTCCAAAATAACTCCAG
304 ORF18_4_37845589_37847420_37859966_37862832_RF OBD159_593 CTTACAGCCTTCCAAAATAACTCCAG
305 ORF18_4_37845589_37847420_37862832_37864637_RR OBD159_597 TGCCACAGCAAGTCTATCAGCATCCG
306 ORF18_4_37845589_37847420_37862832_37864637_RR OBD159_597 TGCCACAGCAAGTCTATCAGCATCCG
307 ORF18_8_22370928_22373682_22443319_22445881_FF OBD159_601 CTTTTACTTCAGGGACCCCAGGTGTC
308 ORF18_8_22370928_22373682_22443319_22445881_FF OBD159_601 CTTTTACTTCAGGGACCCCAGGTGTC
309 ORF18_9_38681931_38686861_38768696_38769724_FF OBD159_605 GCCAGAAGTTCACAGGCAGGGTG
310 ORF18_9_38681931_38686861_38768696_38769724_FF OBD159_605 GCCAGAAGTTCACAGGCAGGGTG
311 ORF18_X_130743981_130757818_130793708_130805512_RR OBD159_609 CTACCACCACCAGCATCCCAATACAC
312 ORF18_X_130743981_130757818_130793708_130805512_RR OBD159_609 CTACCACCACCAGCATCCCAATACAC
313 ORF180_2_195583610_195589061_195640867_195645128_FR OBD159_613 CAGGCTATTGGAATGGCTGAAGTGTG
314 ORF180_2_195583610_195589061_195640867_195645128_FR OBD159_613 CAGGCTATTGGAATGGCTGAAGTGTG
315 ORF181_2_129231919_129233302_129249318_129258610_FF OBD159_617 TACCACTTGAAGGGAGGGTTGCTTTT
316 ORF181_2_129231919_129233302_129249318_129258610_FF OBD159_617 TACCACTTGAAGGGAGGGTTGCTTTT
317 ORF182_7_28717278_28719857_28738396_28739641_RF OBD159_621 TTGGAGGGAGAATACAAAGAGTGAGC
318 ORF182_7_28717278_28719857_28738396_28739641_RF OBD159_621 TTGGAGGGAGAATACAAAGAGTGAGC
319 ORF185_18_58155952_58157838_58215328_58217936_RF OBD159_625 TGTAGAGCCAAATAGCCACAGGGATA
320 ORF185_18_58155952_58157838_58215328_58217936_RF OBD159_625 TGTAGAGCCAAATAGCCACAGGGATA
321 ORF185_4_82581680_82585686_82618801_82621987_FR OBD159_629 CTGGACCTTTCCTTGGCTGCCCT
322 ORF185_4_82581680_82585686_82618801_82621987_FR OBD159_629 CTGGACCTTTCCTTGGCTGCCCT
323 ORF185_6_151443530_151449164_151537463_151538576_FR OBD159_633 CGCCTGTAACCCCAGCATTTTGG
324 ORF185_6_151443530_151449164_151537463_151538576_FR OBD159_633 CGCCTGTAACCCCAGCATTTTGG
325 ORF185_9_131590628_131592768_131652374_131654389_FF OBD159_637 CTGTTCAAACCCGTCAGCAGGAT
326 ORF185_9_131590628_131592768_131652374_131654389_FF OBD159_637 CTGTTCAAACCCGTCAGCAGGAT
327 ORF187_9_28314155_28333777_28367003_28368817_FR OBD159_641 AAACCAGTCAATCCTCAAGTGTGC
328 ORF187_9_28314155_28333777_28367003_28368817_FR OBD159_641 AAACCAGTCAATCCTCAAGTGTGC
329 ORF188_2_209095320_209098567_209157796_209164211_RR OBD159_645 CGTGTCTTTTCTCTGGGACCTGTGAT
330 ORF188_2_209095320_209098567_209157796_209164211_RR OBD159_645 CGTGTCTTTTCTCTGGGACCTGTGAT
331 ORF19_2_78765449_78768597_78804372_78809080_RF OBD159_649 GGAAAAGAGATAAACACACAAATA
332 ORF19_2_78765449_78768597_78804372_78809080_RF OBD159_649 GGAAAAGAGATAAACACACAAATA
333 ORF19_3_107708851_107713617_107779656_107783232_FF OBD159_653 CAATCTAATGATGTCCCTCCACTGCT
334 ORF19_3_107708851_107713617_107779656_107783232_FF OBD159_653 CAATCTAATGATGTCCCTCCACTGCT
335 ORF19_3_24254159_24259126_24306563_24314015_FF OBD159_657 GCCTCCTGATGCTTCCTTCGTGCCCC
336 ORF19_3_24254159_24259126_24306563_24314015_FF OBD159_657 GCCTCCTGATGCTTCCTTCGTGCCCC
337 ORF19_6_169185535_169187937_169230654_169232256_FR OBD159_661 ACACATCCACTGATAGGCAACAACTG
338 ORF19_6_169185535_169187937_169230654_169232256_FR OBD159_661 ACACATCCACTGATAGGCAACAACTG
339 ORF19_8_65560550_65562514_65628655_65630980_FF OBD159_665 CATTTCTCTGCTGCCATCTCGTGGAT
340 ORF19_8_65560550_65562514_65628655_65630980_FF OBD159_665 CATTTCTCTGCTGCCATCTCGTGGAT
341 ORF19_8_89905359_89910373_89958362_89963906_FR OBD159_669 ATCACCTCAGCAGATAGGCATTTA
342 ORF19_8_89905359_89910373_89958362_89963906_FR OBD159_669 ATCACCTCAGCAGATAGGCATTTA
343 ORF19_9_38681931_38686861_38760727_38762491_FR OBD159_673 GCCAGAAGTTCACAGGCAGGGTG
344 ORF19_9_38681931_38686861_38760727_38762491_FR OBD159_673 GCCAGAAGTTCACAGGCAGGGTG
345 ORF190_6_70118659_70128487_70187099_70190406_RF OBD159_677 GAAGTTTCAAATAGGCAAGCCAACCC
346 ORF190_6_70118659_70128487_70187099_70190406_RF OBD159_677 GAAGTTTCAAATAGGCAAGCCAACCC
347 ORF191_10_31830982_31838036_31880198_31881483_FF OBD159_681 TATGGCACTGTGGGAGGTAATGGG
348 ORF191_10_31830982_31838036_31880198_31881483_FF OBD159_681 TATGGCACTGTGGGAGGTAATGGG
349 ORF191_2_72535662_72545373_72613114_72619302_FR OBD159_685 GTTTATTACCTTTCACTGCCAGAT
350 ORF191_2_72535662_72545373_72613114_72619302_FR OBD159_685 GTTTATTACCTTTCACTGCCAGAT
351 ORF194_3_24254159_24259126_24306563_24314015_FF OBD159_657 GCCTCCTGATGCTTCCTTCGTGCCCC
352 ORF194_3_24254159_24259126_24306563_24314015_FF OBD159_657 GCCTCCTGATGCTTCCTTCGTGCCCC
353 ORF194_5_24638174_24644400_24709728_24712840_RF OBD159_689 GATTGAGGGAAGAATACAAGAACTA
354 ORF194_5_24638174_24644400_24709728_24712840_RF OBD159_689 GATTGAGGGAAGAATACAAGAACTA
355 ORF194_X_46916544_46918054_46983732_46995250_RR OBD159_693 AGCACTCTTCCTCCTGACTGTGAGAA
356 ORF194_X_46916544_46918054_46983732_46995250_RR OBD159_693 AGCACTCTTCCTCCTGACTGTGAGAA
357 ORF197_19_44168555_44170532_44257710_44261871_RR OBD159_697 CCTCCCTACTTTTATGGCATCTCTGC
358 ORF197_19_44168555_44170532_44257710_44261871_RR OBD159_697 CCTCCCTACTTTTATGGCATCTCTGC
359 ORF198_7_7793942_7796470_7867790_7872166_RR OBD159_701 GCAAGTTCTCTTCCAGTTGATTTCCT
360 ORF198_7_7793942_7796470_7867790_7872166_RR OBD159_701 GCAAGTTCTCTTCCAGTTGATTTCCT
表1.e7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
287 OBD159_563 TAAGTCTACCTTCTCTCTCCTATTGC OBD159_561_563 -0.003563183
288 OBD159_563 TAAGTCTACCTTCTCTCTCCTATTGC OBD159_561_563 -0.003563183
289 OBD159_567 CCCGAGGGATAGGGATTCTGTTTTGT OBD159_565_567 -0.004067662
290 OBD159_567 CCCGAGGGATAGGGATTCTGTTTTGT OBD159_565_567 -0.004067662
291 OBD159_571 AATCTCCTCTGGTCGCTCCCACC OBD159_569_571 -0.002042219
292 OBD159_571 AATCTCCTCTGGTCGCTCCCACC OBD159_569_571 -0.002042219
293 OBD159_575 ATTGCCAAAAGTGCCCCAAATGATTA OBD159_573_575 -0.002608653
294 OBD159_575 ATTGCCAAAAGTGCCCCAAATGATTA OBD159_573_575 -0.002608653
295 OBD159_579 ACACAACTGACAAATCCTTAGGTGGA OBD159_577_579 -0.003390089
296 OBD159_579 ACACAACTGACAAATCCTTAGGTGGA OBD159_577_579 -0.003390089
297 OBD159_583 TTTCCACTCTCCACCCTCATTTCCTT OBD159_581_583 -0.005421425
298 OBD159_583 TTTCCACTCTCCACCCTCATTTCCTT OBD159_581_583 -0.005421425
299 OBD159_587 CTATGAGGGAGGCATTGTTGTTTC OBD159_585_587 -0.002765198
300 OBD159_587 CTATGAGGGAGGCATTGTTGTTTC OBD159_585_587 -0.002765198
301 OBD159_591 GCTGGCTCCAACAAAACAGGCATTCT OBD159_589_591 -0.003382607
302 OBD159_591 GCTGGCTCCAACAAAACAGGCATTCT OBD159_589_591 -0.003382607
303 OBD159_595 TGCCACAGCAAGTCTATCAGCATCCG OBD159_593_595 -0.001541024
304 OBD159_595 TGCCACAGCAAGTCTATCAGCATCCG OBD159_593_595 -0.001541024
305 OBD159_599 GTTCCATCATAGCAGGATTGGGTCAT OBD159_597_599 -0.003762922
306 OBD159_599 GTTCCATCATAGCAGGATTGGGTCAT OBD159_597_599 -0.003762922
307 OBD159_603 CACTTGATACAATACCAACCCAGAAG OBD159_601_603 -0.002467858
308 OBD159_603 CACTTGATACAATACCAACCCAGAAG OBD159_601_603 -0.002467858
309 OBD159_607 TCTTCCAACATCACTCCCAGGGC OBD159_605_607 -0.002130396
310 OBD159_607 TCTTCCAACATCACTCCCAGGGC OBD159_605_607 -0.002130396
311 OBD159_611 TTCTGCTCACGGAACACAAACACCTT OBD159_609_611 -0.001186762
312 OBD159_611 TTCTGCTCACGGAACACAAACACCTT OBD159_609_611 -0.001186762
313 OBD159_615 GCTGATAATAGTGTGTGTGGGAGGAG OBD159_613_615 -0.002324947
314 OBD159_615 GCTGATAATAGTGTGTGTGGGAGGAG OBD159_613_615 -0.002324947
315 OBD159_619 CAGTGTCTGGATTGAAGTGTAAAGGC OBD159_617_619 -0.001555863
316 OBD159_619 CAGTGTCTGGATTGAAGTGTAAAGGC OBD159_617_619 -0.001555863
317 OBD159_623 GCTAACCACCAGAGTCACACACATCA OBD159_621_623 -0.003169593
318 OBD159_623 GCTAACCACCAGAGTCACACACATCA OBD159_621_623 -0.003169593
319 OBD159_627 TCTGGTTCAAGGAGTGGCTAAGGACC OBD159_625_627 -0.003491777
320 OBD159_627 TCTGGTTCAAGGAGTGGCTAAGGACC OBD159_625_627 -0.003491777
321 OBD159_631 GCATCCCAGCATCTACTTCCCAG OBD159_629_631 -0.000778334
322 OBD159_631 GCATCCCAGCATCTACTTCCCAG OBD159_629_631 -0.000778334
323 OBD159_635 CCTGGATTCTAACTGTGAGTGATAAA OBD159_633_635 -0.003132189
324 OBD159_635 CCTGGATTCTAACTGTGAGTGATAAA OBD159_633_635 -0.003132189
325 OBD159_639 ATCTCAGCATTATTACAACCAGTTCC OBD159_637_639 -0.000924073
326 OBD159_639 ATCTCAGCATTATTACAACCAGTTCC OBD159_637_639 -0.000924073
327 OBD159_643 CCAGAAAGAATGATGAATGTGTTC OBD159_641_643 -0.002329432
328 OBD159_643 CCAGAAAGAATGATGAATGTGTTC OBD159_641_643 -0.002329432
329 OBD159_647 GAGAACATTCCTTTTCCTCTGTAGAA OBD159_645_647 -0.001749435
330 OBD159_647 GAGAACATTCCTTTTCCTCTGTAGAA OBD159_645_647 -0.001749435
331 OBD159_651 GAAAATAGAGGAATGAGATTAGATT OBD159_649_651 -0.002089096
332 OBD159_651 GAAAATAGAGGAATGAGATTAGATT OBD159_649_651 -0.002089096
333 OBD159_655 CTCTAAAATGGCTGCTTCTCAGTGAC OBD159_653_655 -0.000249952
334 OBD159_655 CTCTAAAATGGCTGCTTCTCAGTGAC OBD159_653_655 -0.000249952
335 OBD159_659 CATTTCCTTTTCTACACTGTTCATTCAC OBD159_657_659 -0.004064705
336 OBD159_659 CATTTCCTTTTCTACACTGTTCATTCAC OBD159_657_659 -0.004064705
337 OBD159_663 TATGTTACACCCCTTGGCTACCCAGC OBD159_661_663 -0.002744953
338 OBD159_663 TATGTTACACCCCTTGGCTACCCAGC OBD159_661_663 -0.002744953
339 OBD159_667 GCAGTTGGTGCTCTGTATCCACA OBD159_665_667 -0.002635718
340 OBD159_667 GCAGTTGGTGCTCTGTATCCACA OBD159_665_667 -0.002635718
341 OBD159_671 TTTTCGGCTTTGAAGACTGTTGAT OBD159_669_671 -0.002126128
342 OBD159_671 TTTTCGGCTTTGAAGACTGTTGAT OBD159_669_671 -0.002126128
343 OBD159_675 GCAAGCATCGGAAGCAGACTCAG OBD159_673_675 -0.00192616
344 OBD159_675 GCAAGCATCGGAAGCAGACTCAG OBD159_673_675 -0.00192616
345 OBD159_679 CAATGCCAAGAGCAATGAGGCTACAG OBD159_677_679 -0.002385475
346 OBD159_679 CAATGCCAAGAGCAATGAGGCTACAG OBD159_677_679 -0.002385475
347 OBD159_683 GCCAACACGGAACACACACAAAA OBD159_681_683 -0.002702656
348 OBD159_683 GCCAACACGGAACACACACAAAA OBD159_681_683 -0.002702656
349 OBD159_687 ATGAACTCCACCCAGCAAATGCCT OBD159_685_687 -0.003035174
350 OBD159_687 ATGAACTCCACCCAGCAAATGCCT OBD159_685_687 -0.003035174
351 OBD159_659 CATTTCCTTTTCTACACTGTTCATTCAC OBD159_669_671 -0.000889529
352 OBD159_659 CATTTCCTTTTCTACACTGTTCATTCAC OBD159_669_671 -0.000889529
353 OBD159_691 GTGAAGAGTGGAGGTTTTCTACAGA OBD159_689_691 -0.002347474
354 OBD159_691 GTGAAGAGTGGAGGTTTTCTACAGA OBD159_689_691 -0.002347474
355 OBD159_695 ATGGACGACCCTCTTCCCAGCAAAAT OBD159_693_695 -0.002919455
356 OBD159_695 ATGGACGACCCTCTTCCCAGCAAAAT OBD159_693_695 -0.002919455
357 OBD159_699 TTATGTCTCCCTTCAGTTCCATCAAT OBD159_697_699 -0.001832913
358 OBD159_699 TTATGTCTCCCTTCAGTTCCATCAAT OBD159_697_699 -0.001832913
359 OBD159_703 TTTGTATCCAACCCCTTCCCCAGAGC OBD159_701_703 -0.002112997
360 OBD159_703 TTTGTATCCAACCCCTTCCCCAGAGC OBD159_701_703 -0.002112997
表1.e8
   基因
287 COL19A1; rs771562232
288 COL19A1; rs771562232
289 GPM6A; rs13144140
290 GPM6A; rs13144140
291 ARID1B; rs1057518918; rs1057518691; rs773740590; rs886044620; rs797044859; rs879253746; rs797045278; rs1057518984; rs797045279; rs797045280; rs797045281; rs797045282; rs886041706; rs797045283; rs9406316
292 ARID1B; rs1057518918; rs1057518691; rs773740590; rs886044620; rs797044859; rs879253746; rs797045278; rs1057518984; rs797045279; rs797045280; rs797045281; rs797045282; rs886041706; rs797045283; rs9406316
293 C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256
294 C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256
295 AMMECR1; RGAG1; rs1573036
296 AMMECR1; RGAG1; rs1573036
297 CAPS2; KCNC2
298 CAPS2; KCNC2
299 PUM2; rs111612372
300 PUM2; rs111612372
301 BBX; rs11710737
302 BBX; rs11710737
303 GAFA3; PGM2
304 GAFA3; PGM2
305 GAFA3; PGM2
306 GAFA3; PGM2
307 PIWIL2; PPP3CC; SLC39A14; rs879253763; rs879253764; rs879253765; rs1039778197; rs879253766; rs750281602; rs7833266; rs2272080
308 PIWIL2; PPP3CC; SLC39A14; rs879253763; rs879253764; rs879253765; rs1039778197; rs879253766; rs750281602; rs7833266; rs2272080
309 ANKRD18A; CNTNAP3
310 ANKRD18A; CNTNAP3
311 ARHGAP36; ENOX2
312 ARHGAP36; ENOX2
313 DNAH7; SLC39A10
314 DNAH7; SLC39A10
315 rs7567687; rs1660895
316 rs7567687; rs1660895
317 CREB5; rs56388170
318 CREB5; rs56388170
319 NEDD4L; rs4149601
320 NEDD4L; rs4149601
321 rs13138355; rs72909131
322 rs13138355; rs72909131
323 C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256; rs9479055; rs6931664
324 C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256; rs9479055; rs6931664
325 RAPGEF1; rs4740283; rs11243444
326 RAPGEF1; rs4740283; rs11243444
327 LINGO2; rs10812774
328 LINGO2; rs10812774
329 MAP2; PTH2R
330 MAP2; PTH2R
331 REG3G
332 REG3G
333 BBX; rs670752; rs11710737; rs6437740
334 BBX; rs670752; rs11710737; rs6437740
335 THRB; rs1505297; rs826230; rs826231; rs862247; rs826236; rs826238; rs826240; rs1868575; rs113700287; rs1158265; rs9830674; rs2167115; rs1505307; rs1505283; rs12485694; rs869785; rs869784; rs9310736; rs7622481
336 THRB; rs1505297; rs826230; rs826231; rs862247; rs826236; rs826238; rs826240; rs1868575; rs113700287; rs1158265; rs9830674; rs2167115; rs1505307; rs1505283; rs12485694; rs869785; rs869784; rs9310736; rs7622481
337 THBS2; rs9406328
338 THBS2; rs9406328
339 ARMC1; rs6991838
340 ARMC1; rs6991838
341 NBN; OSGIN2; rs121908973; rs10464867; rs14448; rs13312986; rs1063054; rs2735383; rs142301194; rs1057517262; rs756363734; rs786204181; rs1064795816; rs730881864; rs730881857; rs786201965; rs775397477; rs1057517075; rs786203223; rs786203920; rs1057516869; rs1061302; rs1057516852; rs587782653; rs1057516668; rs587782545; rs1060503466; rs1377580273; rs1057516611; rs61753717; rs864622143; rs786201745; rs749918573; rs766044684; rs1060503481; rs776417262; rs1057516332; rs1060503480; rs587782344; rs759232053; rs786203180; rs587782130; rs864622333; rs876659666; rs730881850; rs1060503467; rs709816; rs746965070; rs587781969; rs1057519588; rs1057517102; rs1057517209; rs121908974; rs876660290; rs767215758; rs876659521
342 NBN; OSGIN2; rs121908973; rs10464867; rs14448; rs13312986; rs1063054; rs2735383; rs142301194; rs1057517262; rs756363734; rs786204181; rs1064795816; rs730881864; rs730881857; rs786201965; rs775397477; rs1057517075; rs786203223; rs786203920; rs1057516869; rs1061302; rs1057516852; rs587782653; rs1057516668; rs587782545; rs1060503466; rs1377580273; rs1057516611; rs61753717; rs864622143; rs786201745; rs749918573; rs766044684; rs1060503481; rs776417262; rs1057516332; rs1060503480; rs587782344; rs759232053; rs786203180; rs587782130; rs864622333; rs876659666; rs730881850; rs1060503467; rs709816; rs746965070; rs587781969; rs1057519588; rs1057517102; rs1057517209; rs121908974; rs876660290; rs767215758; rs876659521
343 ANKRD18A; CNTNAP3
344 ANKRD18A; CNTNAP3
345 COL19A1; rs658805; rs771562232
346 COL19A1; rs658805; rs771562232
347 ARHGAP12; rs211257
348 ARHGAP12; rs211257
349 EXOC6B; rs2421095
350 EXOC6B; rs2421095
351 THRB; rs1505297; rs826230; rs826231; rs862247; rs826236; rs826238; rs826240; rs1868575; rs113700287; rs1158265; rs9830674; rs2167115; rs1505307; rs1505283; rs12485694; rs869785; rs869784; rs9310736; rs7622481
352 THRB; rs1505297; rs826230; rs826231; rs862247; rs826236; rs826238; rs826240; rs1868575; rs113700287; rs1158265; rs9830674; rs2167115; rs1505307; rs1505283; rs12485694; rs869785; rs869784; rs9310736; rs7622481
353 CDH10
354 CDH10
355 JADE3; RP2
356 JADE3; RP2
357 ZNF226; ZNF227; ZNF233; ZNF234; ZNF235
358 ZNF226; ZNF227; ZNF233; ZNF234; ZNF235
359 rs17137412; rs37972
360 rs17137412; rs37972
表1.e9
   探針 基因座
1 ORF1_16_68414192_68421728_68462182_68469147_RF SMPD3; rs2863973
2 ORF1_7_107580951_107585747_107694264_107700145_RF BCAP29; SLC26A4
3 ORF1_8_28471461_28475878_28536205_28541536_FR FBXO16; FZD3
4 ORF10_1_177039010_177043486_177103748_177111201_RF ASTN1
5 ORF10_1_186754095_186757863_186806428_186824334_FR PLA2G4A; rs4140564
6 ORF10_16_5855640_5863059_5995131_5999657_RR NA
7 ORF10_5_160420118_160421640_160489817_160495294_FF PTTG1; SLU7
8 ORF10_6_154294994_154298490_154323035_154324807_FR CNKSR3; IPCEF1; OPRM1
9 ORF10_7_106998395_107001277_107064399_107071524_RR PRKAR2B
10 ORF100_1_77409324_77410804_77438815_77446913_FR AK5; rs6695572
11 ORF101_2_20454246_20457908_20490253_20493006_FR RHOB
12 ORF101_4_152168385_152172738_152191742_152196830_FR FBXW7
13 ORF102_11_9783875_9784929_9820736_9821985_FF SBF2
14 ORF102_21_27949757_27955906_28009218_28020470_RR NA
15 ORF103_18_58202022_58205094_58215328_58217936_RF NEDD4L; rs17064520
16 ORF106_X_39224581_39226649_39303922_39309694_RF NA
17 ORF107_7_38594689_38595956_38633652_38638705_RR AMPH; FAM183B
18 ORF108_11_33554299_33557937_33584612_33595244_RF KIAA1549L
19 ORF11_10_76403646_76410014_76489182_76492128_RR C10orf11; rs10509373; rs11593840
20 ORF11_16_69148710_69150217_69228303_69232126_FF CHTF8; CIRH1A; SNTB2; rs119465999
21 ORF11_18_5035567_5037467_5050686_5056562_FR C18orf42
22 ORF11_22_36707726_36712518_36755709_36758053_RR IFT27; rs5750285
23 ORF110_14_25790070_25797847_25830955_25834255_RF rs12586774; rs862946
24 ORF111_13_34426191_34433129_34463898_34472100_FR NA
25 ORF111_17_76272094_76274120_76321002_76322427_RF PRPSAP1; QRICH2; UBALD2
26 ORF114_3_171158407_171161714_171201848_171211535_RF rs886037841; rs9810566; TNIK
27 ORF115_15_59259334_59261999_59275124_59282145_RF MYO1E
28 ORF115_5_157440866_157447858_157477057_157480958_RR ADAM19; NIPAL4; rs1990950; rs199422216; rs199422217; rs370356566; rs375688767; rs775903553
29 ORF115_9_28293258_28294446_28333777_28339631_FF LINGO2; rs10812774; rs7851437
30 ORF115_X_11308524_11309949_11364232_11365389_RF AMELX; ARHGAP6
31 ORF118_18_11071108_11073538_11120542_11126658_RF PIEZO2; rs7228002
32 ORF12_10_76413183_76419817_76444465_76451876_FR C10orf11
33 ORF12_3_46807202_46811416_46833087_46839270_RF PRSS42; PRSS45; PRSS50
34 ORF120_11_110486946_110488037_110506292_110507507_RR ARHGAP20; FDX1
35 ORF121_3_152326283_152334449_152437463_152442012_RR MBNL1; TMEM14E; rs185894411
36 ORF121_3_182183246_182185848_182234332_182242013_FR NA
37 ORF121_5_68461134_68466125_68476885_68484945_RR rs113246091; rs11960179
38 ORF122_5_7483303_7486792_7540900_7542383_RF ADCY2; rs11948030; rs13166360; rs17231202; rs17826395; rs17826816; rs34043481
39 ORF123_15_80750227_80752685_80777715_80785550_FR ABHD17C; CEMIP; rs11634851
40 ORF124_2_66470757_66475654_66492459_66494190_RF MEIS1; rs11692361
41 ORF125_9_28270698_28275294_28333777_28339631_RF LINGO2; rs10812774; rs7357773
42 ORF127_12_10377744_10380286_10447112_10449189_RF KLRC1; KLRC2; KLRC3; KLRC4; KLRC4-KLRK1; KLRK1; RP11-277P12.6; rs11053781; rs11053802; rs2617167; rs2617170; rs7298732; rs77926410
43 ORF127_16_59884617_59887309_59942777_59950107_RF NA
44 ORF13_1_117665372_117667932_117692654_117695846_FR NA
45 ORF13_1_13894526_13898185_13945271_13952984_RF rs7542939
46 ORF13_12_10157054_10158072_10186674_10187896_FR GABARAPL1; OLR1; TMEM52B
47 ORF13_12_13275230_13278281_13314398_13317948_FR EMP1; rs1479119
48 ORF13_13_110945253_110947067_110985607_110990896_RF ANKRD10
49 ORF13_18_3861153_3868188_3881709_3884399_RF DLGAP1
50 ORF13_2_104860979_104864045_104879992_104882471_RR POU3F3; rs1005999
51 ORF13_2_16010255_16015979_16048422_16049999_FR MYCN
52 ORF13_4_112301960_112303526_112315696_112317586_FR ALPK1; TIFA
53 ORF13_6_137232223_137235679_137362789_137365756_RR IFNGR1; rs13201877
54 ORF130_1_181484002_181486199_181499646_181512034_RF CACNA1E; rs679931
55 ORF131_1_11226037_11228251_11269663_11271072_RR MTOR; UBIAD1
56 ORF132_11_45973750_45978097_46033363_46036668_RF GYLTL1B; PHF21A
57 ORF133_1_103373638_103377704_103450404_103453588_RF RNPC3
58 ORF134_4_22970139_22978081_22994756_23003981_RF rs358231
59 ORF135_21_30984126_30988102_30998437_31002269_FF KRTAP19-8
60 ORF137_12_46952555_46954006_47024050_47025718_RF AMIGO2; SLC38A4
61 ORF137_5_36109952_36117110_36160830_36164969_RF LMBRD2; SKP2
62 ORF138_15_65573794_65596385_65611369_65614380_RF PTPLAD1; SLC24A1; VWA9; rs11632310; rs12906196; rs4366668; rs6494529; rs7165102; rs7178686
63 ORF138_2_87446096_87451261_87563076_87564920_RF PLGLB2
64 ORF138_3_193187039_193193958_193232024_193235318_FR HRASLS
65 ORF139_2_121377681_121382516_121420995_121425842_FF CLASP1; rs62151096
66 ORF14_10_80184350_80188816_80268946_80271961_RF ANXA11; MAT1A; rs10887710; rs1298908; rs2819941; rs3851059; rs7087728
67 ORF14_6_154154477_154163186_154202548_154212736_RR CNKSR3; IPCEF1; OPRM1; rs2236256; rs4869818
68 ORF140_3_169107708_169110909_169149123_169152499_RR MECOM; rs12491785; rs2901381; rs864309724
69 ORF141_1_77409324_77410804_77425166_77437348_FR AK5
70 ORF143_2_21321954_21323411_21382106_21387178_FF rs11897825; rs2337901
71 ORF143_6_146066540_146070987_146155392_146161780_FR GRM1; SHPRH
72 ORF143_7_96186525_96189162_96249981_96253639_FF SLC25A13; rs1060499612; rs746155190; rs763191789; rs80338716; rs80338717; rs80338718; rs80338719; rs80338720; rs879255504
73 ORF144_2_227875567_227878014_227923203_227932124_RF DAW1; rs113776284; rs7591163
74 ORF144_3_16438382_16444965_16548225_16551831_FF RFTN1
75 ORF146_9_8811961_8818994_8830500_8836449_FR PTPRD; rs10120450; rs10120501; rs10121203; rs10758996; rs10815964; rs1434254; rs1836229; rs1975197; rs2053125; rs7048621
76 ORF147_21_30947497_30949256_30984126_30988102_RF KRTAP19-8; rs8134605
77 ORF148_1_229796281_229797522_229849427_229855718_FF rs4925506
78 ORF149_6_149229853_149231712_149287970_149291658_FR TAB2
79 ORF15_1_65274536_65277437_65337853_65339914_FR DNAJC6; rs2477786
80 ORF15_12_98974145_98977016_99003375_99005607_FR ANKS1B; rs7960581
81 ORF15_14_90615204_90618493_90720884_90724855_FR RPS6KA5; TTC7B
82 ORF15_15_33922077_33935249_33988276_33992735_FR AVEN; CHRM5; RYR3; rs661968
表2.a1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
1 38 1 0.340322106
2 54; 59 1; 1 0.232508672; 0.204801276
3 63; 57 3; 3; 3; 3 0.216848517; 0.224771745; 0.202795213; 0.214348844
4 107 2; 3 0.132213333; 0.169050538
5 19 2 0.132230242
6 NA NA NA
7 137; 107 1; 1 0.016382008; 0.046814166
8 163; 163; 140 4; 2; 4; 2; 4; 2 0.117375195; 0.022678142; 0.117375195; 0.022678142; 0.158806697; 0.045194146
9 26 1 0.373699919
10 23 1; 1  0.374075448; 0.376115439
11 27 1 0.37173223
12 143 3; 2 0.107765005; 0.041422991
13 30 1 0.363021342
14 NA NA NA
15 33 4; 2 0.029769861; 0.246924146
16 NA NA NA
17 22; 12 1; 1 0.375573766; 0.314913912
18 65 1; 2 0.198659276; 0.245566966
19 76 4; 4 0.169506823; 0.182516854
20 45; 65; 58 1; 1; 1 0.305019886; 0.198659276; 0.234279681
21 13 1 0.32680192
22 28 1 0.373281001
23 NA NA NA
24 NA NA NA
25 19; 24; 36 1; 1; 1 0.369026848; 0.375945017; 0.336492635
26 NA; 41 NA; 1 NA; 0.325868449
27 45 1; 2 0.305019886; 0.276375861
28 33; 11 1; 1 0.360592644; 0.288260522
29 20 6; 4  7.69e-05; 0.007618647 
30 33; 35 1; 3; 1; 3 0.360592644; 0.112054294; 0.353195365; 0.123360639
31 67 1; 1  0.189085999; 0.164740427 
32 76 4; 4 0.169506823; 0.182516854
33 2; 2; 2 1; 1; 1 0.080664005; 0.080664005; 0.080664005
34 23; 23 1; 1 0.376115439; 0.376115439
35 27; 21 2; 1; 2; 1 0.197546356; 0.37173223; 0.149991246; 0.37425716
36 NA NA NA
37 NA NA NA
38 90 3; 3 0.219233776; 0.208104371
39 40; 46 1; 1 0.330827809; 0.299630226
40 57 4; 2 0.110951788; 0.26588291
41 20 6; 4 7.69e-05; 0.007618647
42 6; 12; 12; 22; 22; 22; 12 1; 1; 1; 1; 1; 1; 1 0.191789359; 0.302214299; 0.302214299; 0.372324987; 0.372324987; 0.372324987; 0.302214299
43 NA NA NA
44 NA NA NA
45 NA NA NA
46 29; 79; 59 2; 2; 2; 3; 2; 2 0.211050406; 0.22548219; 0.219227; 0.224909805; 0.269881341; 0.261532562
47 58 1; 3 0.234279681; 0.216530763
48 26 1 0.373699919
49 53 1 0.238249082
50 86 1 0.11379092
51 63 1 0.184056651
52 11; 11 1; 1 0.301350316; 0.301350316
53 93 2 0.17427462
54 32 1 0.363856051
55 45; 53 1; 1 0.285503815; 0.238249082
56 29; 28 1; 1 0.366349054; 0.369266824
57 14 1 0.325643034
58 NA NA NA
59 60 2; 2 0.268298503; 0.259153243
60 23; 23 1; 1; 1; 1 0.374075448; 0.376115439; 0.374075448; 0.376115439
61 16; 16 1; 2; 1; 2 0.343724359; 0.116490918; 0.343724359; 0.116490918
62 18; 25; 18 1; 1; 1; 1; 1 0.357137933; 0.364965787; 0.375519541; 0.357137933; 0.364965787
63 18 1 0.357137933
64 7 1 0.215038813
65 33 1 0.360592644
66 69; 20 1; 1 0.179812261; 0.366490901
67 163; 163; 140 4; 2; 4; 2; 4; 2 0.117375195; 0.022678142; 0.117375195; 0.022678142; 0.158806697; 0.045194146
68 22 1 0.372324987
69 23 1; 1 0.374075448; 0.376115439
70 NA NA NA
71 28; 28 1; 2; 1; 2 0.373281001; 0.219149094; 0.373281001; 0.219149094
72 33 1 0.360592644
73 38 2; 1 0.255573168; 0.325888812
74 55 2; 3 0.274632664; 0.209439509
75 59 1 0.229012733
76 60 2; 2 0.268298503; 0.259153243
77 NA NA NA
78 26 1; 2 0.375314357; 0.205329626
79 95 1 8.78E-02
80 110 2; 1 0.124006577; 0.042275815
81 88; 76 2; 1 0.167789783; 0.126761755
82 18; 18; 21 1; 1; 1 0.357137933; 0.357137933; 0.369816322
表2.a2
   FDR_HyperG Percent_Sig logFC AveExpr
1 0.375519541 2.63 -0.709015088 -0.709015088
2 0.376115439; 0.376115439 1.85; 169 -0.621824228 -0.621824228
3 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 4.76; 5.26; 5.26 -0.894408824 -0.894408824
4 0.375519541; 0.376115439 1.87; 2.8 -0.762732385 -0.762732385
5 0.375519541 10.53 -0.721208009 -0.721208009
6 NA NA -0.721031531 -0.721031531
7 0.376115439; 0.376115439 0.73; 0.93 -0.677555948 -0.677555948
8 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.45; 1.23; 2.45; 1.23; 2.86; 1.43 -0.627203595 -0.627203595
9 0.376115439 3.85 -0.673868285 -0.673868285
10 0.375519541; 0.376115439 4.35; 4.35 -0.755709116 -0.755709116
11 0.376115439 3.7 -0.715992935 -0.715992935
12 0.375519541; 0.376115439 2.1; 1.4 -0.713103765 -0.713103765
13 0.376115439 3.33 -0.624335514 -0.624335514
14 NA NA -0.725440143 -0.725440143
15 0.375519541; 0.376115439 12.12; 6.06 -0.731354707 -0.731354707
16 NA NA -0.63602694 -0.63602694
17 0.376115439; 0.376115439 4.55; 8.33 -0.676084413 -0.676084413
18 0.375519541; 0.376115439 1.54; 3.08 -0.77604852 -0.77604852
19 0.375519541; 0.376115439 5.26; 5.26 -0.835298815 -0.835298815
20 0.375519541; 0.375519541; 0.375519541 2.22; 1.54; 1.72 -0.717714737 -0.717714737
21 0.376115439 7.69 -0.873959367 -0.873959367
22 0.375519541 3.57 -0.920838995 -0.920838995
23 NA NA -0.973608142 -0.973608142
24 NA NA -0.700803469 -0.700803469
25 0.376115439; 0.376115439; 0.376115439 5.26; 4.17; 2.78 -0.735783774 -0.735783774
26 NA; 0.375519541 NA; 2.44 -0.789035477 -0.789035477
27 0.375519541; 0.376115439 2.22; 4.44 -0.725069084 -0.725069084
28 0.375519541; 0.375519541 3.03; 9.09 -0.758076547 -0.758076547
29 0.008046243; 0.242844385 30; 20 -0.758831154 -0.758831154
30 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.33; 9.09; 2.86; 8.57 -0.858662527 -0.858662527
31 0.375519541; 0.376115439 1.49; 1.49 -0.713531849 -0.713531849
32 0.375519541; 0.376115439 5.26; 5.26 -0.747196209 -0.747196209
33 0.376115439; 0.376115439; 0.376115439 50; 50; 50 -0.683750198 -0.683750198
34 0.376115439; 0.376115439 4.35; 4.35 -0.633467879 -0.633467879
35 0.375519541; 0.376115439; 0.375519541; 0.376115439 7.41; 3.7; 9.52; 4.76 -1.009591423 -1.009591423
36 NA NA -0.909959217 -0.909959217
37 NA NA -0.889155137 -0.889155137
38 0.375519541; 0.376115439 3.33; 3.33 -0.814799341 -0.814799341
39 0.375519541; 0.375519541 2.5; 2.17 -0.708835683 -0.708835683
40 0.375519541; 0.376115439 7.02; 3.51 -0.803329367 -0.803329367
41 0.008046243; 0.242844385 30; 20 -0.754448335 -0.754448335
42 0.375519541; 0.375519541; 0.375519541; 0.375519541; 0.375519541; 0.375519541; 0.375519541 16.67; 8.33; 8.33; 4.55; 4.55; 4.55; 8.33 -1.064914096 -1.064914096
43 NA NA -0.633762538 -0.633762538
44 NA NA -0.759251905 -0.759251905
45 NA NA -0.723893836 -0.723893836
46 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.9; 6.9; 2.53; 3.8; 3.39; 3.39 -0.737400601 -0.737400601
47 0.375519541; 0.376115439 1.72; 5.17 -0.704474086 -0.704474086
48 0.376115439 3.85 -0.750143066 -0.750143066
49 0.376115439 1.89 -0.635359265 -0.635359265
50 0.375519541 1.16 -0.858388718 -0.858388718
51 0.376115439 1.59 -0.690345488 -0.690345488
52 0.376115439; 0.376115439 9.09 -0.738998838 -0.738998838
53 0.375519541 2.15 -0.881183365 -0.881183365
54 0.375519541 3.12 -0.902920687 -0.902920687
55 0.376115439; 0.376115439 2.22; 1.89 -0.624635912 -0.624635912
56 0.376115439; 0.376115439 3.45; 3.57 -0.706506109 -0.706506109
57 0.375519541 7.14 -0.778372431 -0.778372431
58 NA NA -0.775027142 -0.775027142
59 0.375519541; 0.376115439 3.33; 3.33 -0.656602933 -0.656602933
60 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.35; 4.35; 4.35; 4.35 -0.780315542 -0.780315542
61 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.25; 12.5; 6.25; 12.5 -0.636456185 -0.636456185
62 0.375519541; 0.376115439; 0.375519541; 0.375519541; 0.376115439 5.56; 5.56; 4; 5.56; 5.56 -0.848473602 -0.848473602
63 0.375519541 5.56 -0.735464874 -0.735464874
64 0.375519541 14.29 -0.710935297 -0.710935297
65 0.375519541 3.03 -0.757426234 -0.757426234
66 0.375519541; 0.375519541 1.45; 5 -0.782417152 -0.782417152
67 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.45; 1.23; 2.45; 1.23; 2.86; 1.43 -0.723846597 -0.723846597
68 0.375519541 4.55 -0.716912676 -0.716912676
69 0.375519541; 0.376115439 4.35; 4.35 -0.631116211 -0.631116211
70 NA NA -0.737171153 -0.737171153
71 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.57; 7.14; 3.57; 7.14 -0.634695914 -0.634695914
72 0.375519541 3.03 -0.782317451 -0.782317451
73 0.375519541; 0.376115439 5.26; 2.63 -0.707018011 -0.707018011
74 0.375519541; 0.376115439 3.64; 5.45 -0.703124305 -0.703124305
75 0.375519541 1.69 -0.790013857 -0.790013857
76 0.375519541; 0.376115439 3.33; 3.33 -0.808156687 -0.808156687
77 NA NA -0.964755594 -0.964755594
78 0.375519541; 0.376115439 3.85; 7.69 -0.966851209 -0.966851209
79 0.375519541 1.05 -0.808919098 -0.808919098
80 0.375519541; 0.376115439 1.82; 0.91 -0.705391936 -0.705391936
81 0.376115439; 0.376115439 2.27; 1.32 -0.624286859 -0.624286859
82 0.375519541; 0.375519541; 0.375519541 5.56; 5.56; 4.76 -0.764247064 -0.764247064
表2.a3
   t P值 adj.P.Val B FC FC_1 LS
1 -6.967290763 0.0000151 0.000229077 3.208783547 0.611737623 -1.634687753 -1
2 -11.80406641 0.0000000613 0.0000138 8.841413549 0.649848701 -1.538819725 -1
3 -7.314953251 0.00000957 0.000307261 3.752834712 0.537967594 -1.858848025 -1
4 -3.262995276 0.00683472 0.02833772 -2.957420767 0.589379022 -1.696701042 -1
5 -4.968029649 0.00032784 0.001952136 0.032233108 0.606589315 -1.648561843 -1
6 -11.8131196 0.0000000608 0.0000138 8.849745674 0.606663521 -1.648360196 -1
7 -13.12001115 0.0000000189 0.00000773 9.988600988 0.625223561 -1.599427888 -1
8 -6.084970954 0.0000558 0.000984165 1.941696022 0.647430127 -1.544568222 -1
9 -11.85428208 0.0000000585 0.0000136 8.887548932 0.626823735 -1.595344822 -1
10 -5.556841306 0.000125107 0.000969049 1.025796947 0.592255207 -1.688461304 -1
11 -4.638823995 0.000579337 0.004984216 -0.459547887 0.60878599 -1.642613358 -1
12 -7.76455057 0.00000515 0.000112934 4.322293383 0.610006379 -1.639327119 -1
13 -9.506384582 0.000000644 0.0000565 6.498451369 0.6487185 -1.541500667 -1
14 -6.028359188 0.0000599 0.000577932 1.78673893 0.604812498 -1.653404987 -1
15 -5.316223813 0.000184376 0.001280565 0.625473386 0.602338046 -1.660197304 -1
16 -4.915794296 0.000361906 0.003583857 0.022198152 0.643482608 -1.554043556 -1
17 -10.76833726 0.000000168 0.0000254 7.843989171 0.625861609 -1.597797318 -1
18 -9.577396732 0.000000595 0.0000541 6.578326186 0.583964057 -1.71243416 -1
19 -6.8024921 0.0000191 0.000267386 2.96804814 0.560466942 -1.784226554 -1
20 -5.724026908 0.000096 0.000804138 1.299193768 0.608059861 -1.644574925 -1
21 -8.397996218 0.00000236 0.000126895 5.180897834 0.545647306 -1.832685671 -1
22 -8.371982571 0.00000238 0.0000689 5.116567055 0.528201757 -1.893215967 -1
23 -8.769438097 0.00000147 0.000051 5.612539925 0.509230896 -1.963745735 -1
24 -7.105211691 0.0000127 0.000368733 3.458758895 0.615229476 -1.625409768 -1
25 -4.384395187 0.000900518 0.00678304 -0.910104779 0.600491707 -1.665301934 -1
26 -8.592211463 0.00000182 0.000058 5.393630836 0.578730877 -1.727918865 -1
27 -4.491034086 0.000747768 0.005934743 -0.720381163 0.604968075 -1.652979788 -1
28 -7.813359983 0.00000483 0.000108342 4.387795349 0.591284127 -1.691234306 -1
29 -8.336490328 0.00000249 0.0000707 5.071383935 0.590974934 -1.692119144 -1
30 -9.409816538 0.000000718 0.0000605 6.388990029 0.551463564 -1.813356431 -1
31 -5.161266549 0.000237704 0.001542225 0.363462055 0.609825402 -1.63981362 -1
32 -6.206849598 0.0000465 0.000869076 2.130649345 0.595760257 -1.678527542 -1
33 -7.565911003 0.00000684 0.00024651 4.097023669 0.622544902 -1.606309838 -1
34 -4.169100205 0.001316153 0.008687522 -1.296693484 0.644625034 -1.551289428 -1
35 -8.029186511 0.00000366 0.0000901 4.673872264 0.496686892 -2.013340833 -1
36 -4.467590389 0.000771749 0.003675953 -0.847309931 0.532200136 -1.878992381 -1
37 -4.961829562 0.000331268 0.001966927 0.021524681 0.539930217 -1.852091195 -1
38 -5.793538403 0.0000861 0.000744278 1.411706775 0.56848755 -1.759053474 -1
39 -7.545860128 0.00000687 0.000135682 4.02510253 0.6118137 -1.634484485 -1
40 -12.84573625 0.0000000229 0.00000441 9.80966493 0.573025257 -1.745123777 -1
41 -5.670620457 0.000104442 0.000853663 1.212285842 0.59277301 -1.686986391 -1
42 -7.955068433 0.00000402 0.000096 4.57627957 0.47800112 -2.092045307 -1
43 -8.733628985 0.00000157 0.0000989 5.594405878 0.644493388 -1.551606299 -1
44 -8.772524916 0.0000015 0.0000959 5.64148614 0.590802606 -1.692612709 -1
45 -5.968706186 0.0000656 0.000616454 1.692207073 0.605461094 -1.651633787 -1
46 -7.374301451 0.00000883 0.000292636 3.834979572 0.599819113 -1.667169282 -1
47 -10.95636749 0.000000134 0.0000117 8.045169198 0.613666151 -1.629550527 -1
48 -8.951454726 0.00000122 0.000084 5.855865648 0.594544596 -1.681959615 -1
49 -8.483073194 0.00000213 0.000119366 5.286958721 0.643780478 -1.553324516 -1
50 -8.696309388 0.0000016 0.0000538 5.522644501 0.551568236 -1.813012307 -1
51 -6.774937383 0.0000203 0.000503919 2.983571955 0.619705429 -1.613669905 -1
52 -7.132628726 0.0000123 0.000360453 3.497536145 0.599154993 -1.669017218 -1
53 -13.84645685 0.00000000985 0.00000282 10.64128454 0.542921919 -1.841885481 -1
54 -9.38731335 0.000000715 0.0000326 6.348570481 0.534802944 -1.869847597 -1
55 -7.005818947 0.0000146 0.000404802 3.317327772 0.648583438 -1.541821672 -1
56 -9.544081111 0.000000617 0.0000552 6.540917528 0.612802416 -1.631847351 -1
57 -6.081742554 0.0000552 0.000545563 1.870907921 0.583024158 -1.715194793 -1
58 -7.970534443 0.00000394 0.0000949 4.596699819 0.58437763 -1.711222245 -1
59 -6.768401626 0.0000204 0.000506812 2.974016889 0.634370271 -1.576366432 -1
60 -10.05083213 0.000000355 0.0000393 7.097798334 0.582239433 -1.71750648 -1
61 -7.285563893 0.00000996 0.000315494 3.711983185 0.643291181 -1.554506 -1
62 -13.20468402 0.0000000168 0.00000376 10.11545576 0.555372019 -1.800594855 -1
63 -5.640110527 0.000109603 0.000882937 1.162457071 0.600624457 -1.664933868 -1
64 -7.048483109 0.0000135 0.000212228 3.326030289 0.610923949 -1.636864951 -1
65 -4.702742971 0.000514004 0.002723042 -0.430286806 0.591550716 -1.690472133 -1
66 -6.609249636 0.0000252 0.000320879 2.681009587 0.581391888 -1.720010238 -1
67 -5.139253674 0.000246507 0.001584564 0.325978778 0.60548092 -1.651579706 -1
68 -4.285466904 0.00106235 0.004663639 -1.174419268 0.608398003 -1.643660884 -1
69 -5.163922573 0.000239554 0.002683371 0.445398777 0.645676663 -1.548762806 -1
70 -10.21087399 0.00000029 0.0000186 7.268136783 0.599914517 -1.666904155 -1
71 -8.950411064 0.00000122 0.000084 5.854625604 0.644076557 -1.552610462 -1
72 -5.574745047 0.000121588 0.000949047 1.055262273 0.581432068 -1.719891377 -1
73 -4.350938497 0.000946609 0.004268251 -1.056437739 0.612585018 -1.632426472 -1
74 -11.41048444 0.0000000891 0.0000173 8.47287641 0.614240564 -1.628026637 -1
75 -7.480222038 0.00000749 0.000143287 3.934706397 0.578338537 -1.729091071 -1
76 -7.948752109 0.00000405 0.0000965 4.567931437 0.571111093 -1.750972817 -1
77 -3.798122869 0.00254516 0.008973828 -2.064090726 0.512365204 -1.951732852 -1
78 -13.63931618 0.0000000122 0.00000609 10.40829899 0.511621498 -1.95456994 -1
79 -8.037377146 0.00000362 0.0000895 4.684615618 0.570809362 -1.751898387 -1
80 -9.289749362 0.000000799 0.0000348 6.235078318 0.613275858 -1.630587585 -1
81 -6.240283826 0.0000442 0.000840053 2.182113056 0.648740378 -1.541448681 -1
82 -5.232751927 0.000211328 0.001412883 0.484737935 0.58876056 -1.698483336 -1
表2.a4
      探針序列 探針 位置
偵測到之環 60 mer Chr
1 sAD AAACTCAATGATAGAATTATTAAGGATTTCGACATTTTAAAAGGGCACTTGGAATTTCAC 16
2 mAD TTTTCCAGTCCTATTTTCTATGGCAATGTCGAAAGTCTTTGAAAATAAACTCACCTAACG 7
3 mAD CTAAAATGAATCCTAAAGGTCTTTTTGTTCGATTTTGAAAAGCACATGTTTCCTTCCTTT 8
4 mAD ACTGAATTCTCACAACCATCCTGGTGTTTCGAATAAAAGAATCTGGATCTATTAAATGTC 1
5 sAD TAATGATAAAAAAATCAAATAAAAACTGTCGATAGTGATAAAGACATACTCATAAAATAT 1
6 mAD AGTTGAAGGCATCACATATGTTCTGATTTCGAAATGTTAAGTGTTTTAAAAACAACTTTC 16
7 mAD AATATGGAGAGCAAAAAAAAAAAGCCTCTCGAAACAGAGGTATCAAGTCCTTTGTTGCAA 5
8 mAD TTCATGAGTCATAGTCAATTATATAATCTCGATGTGACAAGTGCTTTTAAACAAGAGATT 6
9 mAD TGTTTCACAAATAGAATAAGACCATTTCTCGATATTTCGTCTTACTCTGCCCCACCTCCA 7
10 sAD ACATTTATTCCCTAATACTCTTCTCTGTTCGAACCAGAAGAACATTGTCCTTAAACCAGA 1
11 mAD CCAGCTTATTCTAAGTCCTCAATAAATCTCGAGAACAGCTACTTTCTATCTTCTGTTACA 2
12 sAD AAACTTTAAAACAAAATGAAGTTCTAATTCGAAGGCTCTTTCTCTAGCTTTTTCCTTTGG 4
13 mAD GACTCAACTACAAATAACTACAACCTCTTCGACATTTGCATTTAAATTGCTTTGAGCCTT 11
14 sAD AACATTTGCAACTTGATGATATTATGTTTCGAAGGATAAAACCACTAAGCATTATATTTA 21
15 sAD CGTAATGTTATTTTTAAAAACGTACTTTTCGAGGCATTCCAATAAAAATAAGTAAATTCT 18
16 mAD GACCACAAAGTGAAGGTAAAAATAAAATTCGACTTTACAAATAATAATAATAGTCCAATG X
17 mAD AAATATCAGGAGAATCCACATAGTAGTCTCGAACATCAGACTTGAATTTCTTGTTTTGGA 7
18 mAD CTATATTTGCTTCATAATTTTTTCTTTTTCGACTTAACAACTTGTATAGGTTTGGTATTA 11
19 sAD ACTCTTCAAAATTATAATTATCAACAATTCGATTTTGTTACTTGTTATTGGTCTTTTCAG 10
20 sAD TCTTTGTTAGGTTTTCTCTTATGTTCTTTCGAAGTCTAACTTGAATATCTATTACTTTTA 16
21 mAD AACAAAATAAAGCTTGACTTTTAACAAATCGATGTAGTCTTTGTGGCCAATCTTTATCAC 18
22 sAD CAATATCCTTTGTATTATTTTCTTTACTTCGAATCCATGGGCTCTGAAACAAAACCATTT 22
23 sAD GAATTATCAAATTATATTCCAGGTTTGTTCGATATCTCTGCTCAATTTTTAAAATGCTAT 14
24 mAD TACGTTAATTAAATAAATTTGTGCTCACTCGAAACAGGTTGGTTTTACACAAAGAGGTGT 13
25 mAD AAAAATATATTTATCAAACAACAGTCTTTCGAGAGGGGCCGGGCCCGGCACCCACCGCAT 17
26 sAD CCTAGAAGAGATCAAGGTAGAAAGACTATCGAGAGGACATAAATAAGTTCTACCTACTTC 3
27 mAD AGCCATAGGGAATTTAAATAACTTCTGTTCGATTATGTCACATGTAACATGAGTGATTCC 15
28 sAD TCAAATTCTCATTTTTTAAGGTTTATTTTCGAAGAATCTCAGGATCATTCAGGCCTTTAA 5
29 sAD CAGAAAATTCAAATAAACTGTTAAAATTTCGATAGATCCTAATATTACTATTTAGTGGGC 9
30 mAD ACTTGCAGACAAATGTCTTCAAATTCATTCGATGTTATAGAATCTTGATCCTTCATCATA X
31 sAD ATATTTTTTTTTTTTTGTATTCCCAGAATCGAAAAGAAGTTCTTTTTATCCCAAAGGAGT 18
32 mAD TATTGAGTTTTAAGTGTTTTGTATATTTTCGATACTGGGTTCAAATCTCAATTTTATTTT 10
33 mAD CTACAGTATATCATCTAAGATGTCTTCTTCGACTAACGTTTACTTGGCACTTGATGTTTT 3
34 mAD AAAGAAGAAAAAAATGAAATAATTGGTTTCGACAGAAGCTAGTTATAATGTCGTTATTAT 11
35 sAD ATAATAATAAATAACATTAAAGTTAAACTCGAGATGCTCTTATTCTCTGGGCTTCATATT 3
36 sAD ACACCCATTTTTAGGAATATTACAGTTGTCGATTGTATTTTGACAGGAAAGCAGAATGTA 3
37 sAD TATTTTTCTTTATCTGAATTTATAACTTTCGATTTTTTTCATGCTCCTCTCCAATTCTGT 5
38 sAD TATTACAGAAAAAAAAAAATGGATCTCTTCGAAAAATTTTGAGAGTAGTCATCTGCTGGG 5
39 sAD TAGTACTAATTGGTATCCTTTTGTAACTTCGACCTTTCTCCATTTGGGCCAAATGCCCAG 15
40 sAD ACTCCTTTCAATCAGTTGAATCAACAAATCGAACACAGAAGTATTTATCTGAAAAGTGGA 2
41 sAD GCCCACTAAATAGTAATATTAGGATCTATCGAATTTGTGCTTGTTGGGAAAATAGTAATT 9
42 sAD CATATGGATGATTTCTACAAATATATTATCGAGACTTATCAAATTGTATACTTTATATAT 12
43 mAD CAAAATCCTGAGGAAAGTTTCTAATTTATCGAACTGCAAACCATCAAAGTTACCAGGAAA 16
44 mAD CTTGACTGTGTTGTATTTTTTGTTTTTTTCGACTGACTGATTAAAACATTCATTATCTGA 1
45 sAD TACATTTTTAGCTCATCATAAAAGATATTCGACTTTTTTGGCGTTAATTCTCACTGGGAA 1
46 mAD ACAGATTAAAACTATGAGGATATACCATTCGAGTAATATTAAAGATTCCAGGACTCACAA 12
47 sAD TTTTTTGTTGTTTTTTTTTAATACTCCCTCGATAGTATATATAAGACAGGAATATGTGTG 12
48 mAD TACAATTTTGATGAGCATTATAAAGAAATCGAATGCTGTTATTTTCCAGAGTTAATTAGG 13
49 mAD AATATATAAAATGATGTGGAATAATGTTTCGATTATTCAGGAAAAACTCCTTTACAAAAA 18
50 sAD GTTAAAATTATTTAAAATATTACACTTATCGAATGCATTTTGTGACTATAGAGGGTGGCT 2
51 mAD TATTTCATTCTTTCAACAAATATTTGACTCGAGTTGTTTCATTTTTTTAGACATTGGTTT 2
52 mAD TCTCTGAATGTCTTTTGAATCTACCATATCGAATAGCAAGCATGCAACAATGCTTGTGAC 4
53 sAD TTAAATCAAAATCTTTGACTCTTAAAAATCGAAAGGTAAGGCAGAGTGAGATGGAATCTA 6
54 sAD CATTTGCAGATTTGTTAATAGTATAAAATCGATTGGCCATATCCTTTCTTGCCCACCATA 1
55 mAD CACCTTGGTTATAATGTATTTTTAAATTTCGAGATCAGCTTGGTAAAACCCTATCTCTAC 1
56 mAD CTTTTAAAAGGTTTCTTGCTTTTCTGACTCGATTTAAAGAACTTCTGAAGTGGTGATCCA 11
57 sAD AGTCCTTATTGAGTGATCTTTATATTACTCGAAAAACTCTTATCAGGATAAGAATAATGG 1
58 sAD GTAAAAACAAAGCAAATTCTTCAAAATTTCGAGTTGTTTCCAATAATTTTAAAAGATGGC 4
59 mAD AATGAAACTGTAAGTTTCCCCAATTAAATCGAATGTTTAAAATTTTGGTGAATTGTTATT 21
60 mAD GAGACAACTCAATATTAATAATGCAGATTCGATGAGTTTCTGTATTCAGGATTGGTGTTT 12
61 mAD CAAACATTCTGACTACAATACAGTATTATCGATTTTCACCTTCTTCTTGCCTTTGCCTTT 5
62 sAD AACAATAAATCCCTAATATCATCAAATATCGATTTTAGTATGACAACTAAGAACATAAAA 15
63 sAD ATATTATGTTCTAGAAAAGGTAGAATTATCGAGATTTACTCATAGGCACTGAGTTTCAAA 2
64 sAD CTATATTATCTGCATTTTTCAAATTCATTCGACTTGGGTAGAAACAATAATAGCTAACAC 3
65 sAD GAACAAATTTTGTTTTACAATTTGGTCCTCGATGAATTTAATCCAGCCACATTTATTATG 2
66 sAD GGAAAGTATAAAATTCTGAATTTTCATGTCGACTTATGATTTTTCAACTTTATGATGGTG 10
67 sAD TTATATTGGAAATCTGTTTCAACAATAATCGAAACAACACCAAATAAGCTTTTCCTCTTA 6
68 sAD ATAGAAATTGTTTACAGAATGATTTTATTCGAGCTATGAGCTGTTCTATTTTCTTCCTGT 3
69 mAD ACATTTATTCCCTAATACTCTTCTCTGTTCGACAAAATTATCCTTCAAAAATGAAGGAGA 1
70 sAD CACAAAACTGAATTTATTTTTATCGTCTTCGACAGAGCTACATTAAAAAGGAGAATCTCC 2
71 mAD CTGCTAATTTTAATTCACTAAGAAACTATCGATATACCATAGGTGTATAGTAGGTTATGC 6
72 sAD AATTTCTCTTTACAGCCTTTAAAATTTATCGATGTTATAGAGTCACTCTTATTGCTCCTG 7
73 sAD TCTATATAAGAAATTCGTAGGATGAATATCGAATAATCTACCCATGGACATTTGTATCAC 2
74 mAD TTTAGTATTAGAAATGTTTTGGTCTTTATCGAAAAACATGGCTCTGAAACCCAAGCTTAT 3
75 sAD CACTCTAGTCCACTACTAGTTGCAATGTTCGAATCATGGACAGATGAGAGGTTTCAAGCA 9
76 sAD AATGAAACTGTAAGTTTCCCCAATTAAATCGAATCCGTAAATTCTAACACCTCCCTTCTT 21
77 sAD CTTAATCAATTGGAGTTTAACCTTTGGTTCGATTTTTCAATGTTTGTGACAAAACCGGTT 1
78 mAD AAAACACCTAAAATTAAGCAAAGTATTTTCGATCATAAAATTATGTTAAGCAAAGAATTA 6
79 sAD ACTTTTGTGATTTTATGATTTGTAATTGTCGAGTATATAGAGGGACATCAGTATTCTTAC 1
80 sAD AAGCAAACAATGAAATTGAAGGGAAATATCGAGATTTTAATAGGAATTGCACTGAATCTA 12
81 mAD CACAATGATGCTCACCGTCGTGTGAGCTTCGACCCTAGTTCCTGACACGTAAATATTTGA 14
82 sAD TAAAAATGATTTTCAAGACGTGGAAAATTCGATTTTAATGAACAGTATCAAGTGCAAAAA 15
表2.a5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
1 68414192 68414223 68469116 68469147 16 68414192 68418193 68465146 68469147
2 107580951 107580982 107700114 107700145 7 107580951 107584952 107696144 107700145
3 28475847 28475878 28536205 28536236 8 28471877 28475878 28536205 28540206
4 177039010 177039041 177111170 177111201 1 177039010 177043011 177107200 177111201
5 186757832 186757863 186806428 186806459 1 186753862 186757863 186806428 186810429
6 5855640 5855671 5995131 5995162 16 5855640 5859641 5995131 5999132
7 160421609 160421640 160495263 160495294 5 160417639 160421640 160491293 160495294
8 154298459 154298490 154323035 154323066 6 154294489 154298490 154323035 154327036
9 106998395 106998426 107064399 107064430 7 106998395 107002396 107064399 107068400
10 77410773 77410804 77438815 77438846 1 77406803 77410804 77438815 77442816
11 20457877 20457908 20490253 20490284 2 20453907 20457908 20490253 20494254
12 152172707 152172738 152191742 152191773 4 152168737 152172738 152191742 152195743
13 9784898 9784929 9821954 9821985 11 9780928 9784929 9817984 9821985
14 27949757 27949788 28009218 28009249 21 27949757 27953758 28009218 28013219
15 58202022 58202053 58217905 58217936 18 58202022 58206023 58213935 58217936
16 39224581 39224612 39309663 39309694 X 39224581 39228582 39305693 39309694
17 38594689 38594720 38633652 38633683 7 38594689 38598690 38633652 38637653
18 33554299 33554330 33595213 33595244 11 33554299 33558300 33591243 33595244
19 76403646 76403677 76489182 76489213 10 76403646 76407647 76489182 76493183
20 69150186 69150217 69232095 69232126 16 69146216 69150217 69228125 69232126
21 5037436 5037467 5050686 5050717 18 5033466 5037467 5050686 5054687
22 36707726 36707757 36755709 36755740 22 36707726 36711727 36755709 36759710
23 25790070 25790101 25834224 25834255 14 25790070 25794071 25830254 25834255
24 34433098 34433129 34463898 34463929 13 34429128 34433129 34463898 34467899
25 76272094 76272125 76322396 76322427 17 76272094 76276095 76318426 76322427
26 171158407 171158438 171211504 171211535 3 171158407 171162408 171207534 171211535
27 59259334 59259365 59282114 59282145 15 59259334 59263335 59278144 59282145
28 157440866 157440897 157477057 157477088 5 157440866 157444867 157477057 157481058
29 28294415 28294446 28339600 28339631 9 28290445 28294446 28335630 28339631
30 11308524 11308555 11365358 11365389 X 11308524 11312525 11361388 11365389
31 11071108 11071139 11126627 11126658 18 11071108 11075109 11122657 11126658
32 76419786 76419817 76444465 76444496 10 76415816 76419817 76444465 76448466
33 46807202 46807233 46839239 46839270 3 46807202 46811203 46835269 46839270
34 110486946 110486977 110506292 110506323 11 110486946 110490947 110506292 110510293
35 152326283 152326314 152437463 152437494 3 152326283 152330284 152437463 152441464
36 182185817 182185848 182234332 182234363 3 182181847 182185848 182234332 182238333
37 68461134 68461165 68476885 68476916 5 68461134 68465135 68476885 68480886
38 7483303 7483334 7542352 7542383 5 7483303 7487304 7538382 7542383
39 80752654 80752685 80777715 80777746 15 80748684 80752685 80777715 80781716
40 66470757 66470788 66494159 66494190 2 66470757 66474758 66490189 66494190
41 28270698 28270729 28339600 28339631 9 28270698 28274699 28335630 28339631
42 10377744 10377775 10449158 10449189 12 10377744 10381745 10445188 10449189
43 59884617 59884648 59950076 59950107 16 59884617 59888618 59946106 59950107
44 117667901 117667932 117692654 117692685 1 117663931 117667932 117692654 117696655
45 13894526 13894557 13952953 13952984 1 13894526 13898527 13948983 13952984
46 10158041 10158072 10186674 10186705 12 10154071 10158072 10186674 10190675
47 13278250 13278281 13314398 13314429 12 13274280 13278281 13314398 13318399
48 110945253 110945284 110990865 110990896 13 110945253 110949254 110986895 110990896
49 3861153 3861184 3884368 3884399 18 3861153 3865154 3880398 3884399
50 104860979 104861010 104879992 104880023 2 104860979 104864980 104879992 104883993
51 16015948 16015979 16048422 16048453 2 16011978 16015979 16048422 16052423
52 112303495 112303526 112315696 112315727 4 112299525 112303526 112315696 112319697
53 137232223 137232254 137362789 137362820 6 137232223 137236224 137362789 137366790
54 181484002 181484033 181512003 181512034 1 181484002 181488003 181508033 181512034
55 11226037 11226068 11269663 11269694 1 11226037 11230038 11269663 11273664
56 45973750 45973781 46036637 46036668 11 45973750 45977751 46032667 46036668
57 103373638 103373669 103453557 103453588 1 103373638 103377639 103449587 103453588
58 22970139 22970170 23003950 23003981 4 22970139 22974140 22999980 23003981
59 30988071 30988102 31002238 31002269 21 30984101 30988102 30998268 31002269
60 46952555 46952586 47025687 47025718 12 46952555 46956556 47021717 47025718
61 36109952 36109983 36164938 36164969 5 36109952 36113953 36160968 36164969
62 65573794 65573825 65614349 65614380 15 65573794 65577795 65610379 65614380
63 87446096 87446127 87564889 87564920 2 87446096 87450097 87560919 87564920
64 193193927 193193958 193232024 193232055 3 193189957 193193958 193232024 193236025
65 121382485 121382516 121425811 121425842 2 121378515 121382516 121421841 121425842
66 80184350 80184381 80271930 80271961 10 80184350 80188351 80267960 80271961
67 154154477 154154508 154202548 154202579 6 154154477 154158478 154202548 154206549
68 169107708 169107739 169149123 169149154 3 169107708 169111709 169149123 169153124
69 77410773 77410804 77425166 77425197 1 77406803 77410804 77425166 77429167
70 21323380 21323411 21387147 21387178 2 21319410 21323411 21383177 21387178
71 146070956 146070987 146155392 146155423 6 146066986 146070987 146155392 146159393
72 96189131 96189162 96253608 96253639 7 96185161 96189162 96249638 96253639
73 227875567 227875598 227932093 227932124 2 227875567 227879568 227928123 227932124
74 16444934 16444965 16551800 16551831 3 16440964 16444965 16547830 16551831
75 8818963 8818994 8830500 8830531 9 8814993 8818994 8830500 8834501
76 30947497 30947528 30988071 30988102 21 30947497 30951498 30984101 30988102
77 229797491 229797522 229855687 229855718 1 229793521 229797522 229851717 229855718
78 149231681 149231712 149287970 149288001 6 149227711 149231712 149287970 149291971
79 65277406 65277437 65337853 65337884 1 65273436 65277437 65337853 65341854
80 98976985 98977016 99003375 99003406 12 98973015 98977016 99003375 99007376
81 90618462 90618493 90720884 90720915 14 90614492 90618493 90720884 90724885
82 33935218 33935249 33988276 33988307 15 33931248 33935249 33988276 33992277
表2.a6
   探針 PCR- 引子 1_ID PCR_ 引子 1
1 ORF1_16_68414192_68421728_68462182_68469147_RF OBD159_705 TGGAGAGGTGGAGGGAGGTAGGA
2 ORF1_7_107580951_107585747_107694264_107700145_RF OBD159_709 CAACTGTGACTTGACTCCTTGCTAAG
3 ORF1_8_28471461_28475878_28536205_28541536_FR OBD159_713 ATTGACTAACAACAACAAGAAAGC
4 ORF10_1_177039010_177043486_177103748_177111201_RF OBD159_717 GCCCCTCTTCTTTGCCAAGCACT
5 ORF10_1_186754095_186757863_186806428_186824334_FR OBD159_721 ACAAGAGATGCTCCACAATACATTTG
6 ORF10_16_5855640_5863059_5995131_5999657_RR OBD159_725 GAAAGTAATCTTATTGACGATAGC
7 ORF10_5_160420118_160421640_160489817_160495294_FF OBD159_729 GCATAAGAGAATGACTCAAACGCTGC
8 ORF10_6_154294994_154298490_154323035_154324807_FR OBD159_733 TCCCAAGTGGTCCCCAAAATGTCTTT
9 ORF10_7_106998395_107001277_107064399_107071524_RR OBD159_737 GGGACAGTGTGGTCTCCAGAATC
10 ORF100_1_77409324_77410804_77438815_77446913_FR OBD159_741 AAGTCAGAAAGCCACAAGATAAAT
11 ORF101_2_20454246_20457908_20490253_20493006_FR OBD159_745 GCCCTCTACTGCCTCAGGTTCTT
12 ORF101_4_152168385_152172738_152191742_152196830_FR OBD159_749 CACATAGTTGCTTCTCTTCAAGGTGT
13 ORF102_11_9783875_9784929_9820736_9821985_FF OBD159_753 GCAGACAGGAGATAAGAGCCATCAGG
14 ORF102_21_27949757_27955906_28009218_28020470_RR OBD159_757 CCAGTGAGCATAAACAACCCTCT
15 ORF103_18_58202022_58205094_58215328_58217936_RF OBD159_761 TGTAGAGCCAAATAGCCACAGGGATA
16 ORF106_X_39224581_39226649_39303922_39309694_RF OBD159_765 TGAAAGAAAGAGGTTGTCAAGAAT
17 ORF107_7_38594689_38595956_38633652_38638705_RR OBD159_769 ATGTCTTTATCTTGCTTCCTTTAGGG
18 ORF108_11_33554299_33557937_33584612_33595244_RF OBD159_773 GAATAAGCACTTCTTCTTGGATTAGC
19 ORF11_10_76403646_76410014_76489182_76492128_RR OBD159_777 ACAAAATAGAACCCTGGTCCCACC
20 ORF11_16_69148710_69150217_69228303_69232126_FF OBD159_781 TGCCTGGCTGATGTTTCTTGGATA
21 ORF11_18_5035567_5037467_5050686_5056562_FR OBD159_785 GCATCATTTGAAACCTTGGTGGCTGC
22 ORF11_22_36707726_36712518_36755709_36758053_RR OBD159_789 GTTGAGTTTGGTCTCCCTGCCCC
23 ORF110_14_25790070_25797847_25830955_25834255_RF OBD159_793 CCTTAGAGCCAATCATTACAGCGTTC
24 ORF111_13_34426191_34433129_34463898_34472100_FR OBD159_797 CACAGTGGGCTCAGTGTCAACAAACC
25 ORF111_17_76272094_76274120_76321002_76322427_RF OBD159_801 GACAGAGCAAGACTCCATCTCAA
26 ORF114_3_171158407_171161714_171201848_171211535_RF OBD159_805 CAGCAAACTGGCATAGCACAATCTC
27 ORF115_15_59259334_59261999_59275124_59282145_RF OBD159_809 CACACTGGCATTCCCTATTGGGC
28 ORF115_5_157440866_157447858_157477057_157480958_RR OBD159_813 CTGAATGGTGTGTCGCAGAGCAG
29 ORF115_9_28293258_28294446_28333777_28339631_FF OBD159_817 GACATAGAATAATCTCCATCCATTGC
30 ORF115_X_11308524_11309949_11364232_11365389_RF OBD159_821 AGCCAACAATACACAGAGCAGGACAG
31 ORF118_18_11071108_11073538_11120542_11126658_RF OBD159_825 CCTCACACAGTCCTCTTCCCACC
32 ORF12_10_76413183_76419817_76444465_76451876_FR OBD159_829 CCACCAGCAGTTATTGAGCATTCCTT
33 ORF12_3_46807202_46811416_46833087_46839270_RF OBD159_833 CCAGCAAAAGGCAGGAATCAGTGC
34 ORF120_11_110486946_110488037_110506292_110507507_RR OBD159_837 CCTGTCAGTGGTGGGTAGGAGGG
35 ORF121_3_152326283_152334449_152437463_152442012_RR OBD159_841 CTTGATAATAAACGCAGCAGAAAT
36 ORF121_3_182183246_182185848_182234332_182242013_FR OBD159_845 GAGACTGAGGTTGCTTCCAATGTTCC
37 ORF121_5_68461134_68466125_68476885_68484945_RR OBD159_849 CAGTGGTAATCTATGGGTGGTAGGAA
38 ORF122_5_7483303_7486792_7540900_7542383_RF OBD159_853 TTTGTCACAGGGTCCATAACTGGGTT
39 ORF123_15_80750227_80752685_80777715_80785550_FR OBD159_857 GGTCATTCCTCTCTCACTGTGTTTCA
40 ORF124_2_66470757_66475654_66492459_66494190_RF OBD159_861 CTCAAAGTTGTTCTCAGCCTTCTCAC
41 ORF125_9_28270698_28275294_28333777_28339631_RF OBD159_865 GCCTAAGTCCAGTAGTATGGTGGCTG
42 ORF127_12_10377744_10380286_10447112_10449189_RF OBD159_869 ATGTATTGTGGATTGAAAGCATTT
43 ORF127_16_59884617_59887309_59942777_59950107_RF OBD159_873 CTTGGTGAAAGGGAGTGAATCTCTGC
44 ORF13_1_117665372_117667932_117692654_117695846_FR OBD159_877 CTCCTCCCAACTTCTACTCACCCC
45 ORF13_1_13894526_13898185_13945271_13952984_RF OBD159_881 GTGCTGTGTGACCTTGGGATGTCC
46 ORF13_12_10157054_10158072_10186674_10187896_FR OBD159_885 CCTGAGCAACAAGAGCGAAACTC
47 ORF13_12_13275230_13278281_13314398_13317948_FR OBD159_889 TCATTCTCCACCTCCCACCCTGC
48 ORF13_13_110945253_110947067_110985607_110990896_RF OBD159_893 GCTGAAGCAGTGTGGCAACAGGA
49 ORF13_18_3861153_3868188_3881709_3884399_RF OBD159_897 CTCTCTCTACAAATCAGGTTCCACTG
50 ORF13_2_104860979_104864045_104879992_104882471_RR OBD159_901 CCTGGAACTTGGGCAAACTAAACTCC
51 ORF13_2_16010255_16015979_16048422_16049999_FR OBD159_905 GGATGGTAGTTTCCACCGTCTGG
52 ORF13_4_112301960_112303526_112315696_112317586_FR OBD159_909 GATTCATCATTTACTGCCTCCACCAG
53 ORF13_6_137232223_137235679_137362789_137365756_RR OBD159_913 GGTCATCATCGTGGACAAGGAAAGCC
54 ORF130_1_181484002_181486199_181499646_181512034_RF OBD159_917 GCGTTGGAGAAGACCTCAGCCAT
55 ORF131_1_11226037_11228251_11269663_11271072_RR OBD159_921 GTGTTAAATATGTTGAAT
56 ORF132_11_45973750_45978097_46033363_46036668_RF OBD159_925 GCTACATCTGGGTGAACTTTAGACTC
57 ORF133_1_103373638_103377704_103450404_103453588_RF OBD159_929 GTGTTCATTACCTGATTTGATTTA
58 ORF134_4_22970139_22978081_22994756_23003981_RF OBD159_933 GGGTGCTACGAGATAGGGAAAGGATG
59 ORF135_21_30984126_30988102_30998437_31002269_FF OBD159_937 TGGGTTGACTAAAATCCCGTAAAAGC
60 ORF137_12_46952555_46954006_47024050_47025718_RF OBD159_941 CCTGTGCCCAGTCTCCGTCTTTTATC
61 ORF137_5_36109952_36117110_36160830_36164969_RF OBD159_945 TTCACTTACCCTCACCGCACTCAACC
62 ORF138_15_65573794_65596385_65611369_65614380_RF OBD159_949 TCACCCAGTTTCTGCTGTCAATGC
63 ORF138_2_87446096_87451261_87563076_87564920_RF OBD159_953 AATGAACTATCAGGCTATGTAAAA
64 ORF138_3_193187039_193193958_193232024_193235318_FR OBD159_957 GACAGCAGGACACCTCAGTGCCATAA
65 ORF139_2_121377681_121382516_121420995_121425842_FF OBD159_961 TTAGTCTCTTCTTTCCTTGACAAA
66 ORF14_10_80184350_80188816_80268946_80271961_RF OBD159_965 GCATAGGGTAGTTGCTCCTTGAGTTT
67 ORF14_6_154154477_154163186_154202548_154212736_RR OBD159_969 CCTCTGGTGGCAGTCATCAAAATCGC
68 ORF140_3_169107708_169110909_169149123_169152499_RR OBD159_973 TATGGTTCCAGCAGATAGTTTCCCTG
69 ORF141_1_77409324_77410804_77425166_77437348_FR OBD159_977 AAGTCAGAAAGCCACAAGATAAAT
70 ORF143_2_21321954_21323411_21382106_21387178_FF OBD159_981 CAATCTTGTGGTATCCTATGTCTTAG
71 ORF143_6_146066540_146070987_146155392_146161780_FR OBD159_985 GGCTAAACCCACACCCTGTAATAACC
72 ORF143_7_96186525_96189162_96249981_96253639_FF OBD159_989 GTGACACCAACACGGGATTCTTTCGC
73 ORF144_2_227875567_227878014_227923203_227932124_RF OBD159_993 CTTCTTCTCCTTGCCTTTCCTCTGGA
74 ORF144_3_16438382_16444965_16548225_16551831_FF OBD159_997 CCACTACAACCACCATCACTCGCTGT
75 ORF146_9_8811961_8818994_8830500_8836449_FR OBD159_1001 AACTAACCAGGAAAACGACATAGCAC
76 ORF147_21_30947497_30949256_30984126_30988102_RF OBD159_1005 GCATTCCAGGTCCAAGATGTCCT
77 ORF148_1_229796281_229797522_229849427_229855718_FF OBD159_1009 CACAGCAACAAAAGCAACCTGGTGTC
78 ORF149_6_149229853_149231712_149287970_149291658_FR OBD159_1013 ATTGACTGTCTTGGGAAAAGCACTTA
79 ORF15_1_65274536_65277437_65337853_65339914_FR OBD159_1017 TTCTGAGTCTGGTTCTCCATTCAAAT
80 ORF15_12_98974145_98977016_99003375_99005607_FR OBD159_1021 CAGTGGCTCCAAAGTCAAAACAAGGT
81 ORF15_14_90615204_90618493_90720884_90724855_FR OBD159_1025 AACTCCTGGCTCAAGGTGTTGCTTTG
82 ORF15_15_33922077_33935249_33988276_33992735_FR OBD159_1029 GGCTCCACTTTCTCCTATTTTGAACC
表2.a7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
1 OBD159_707 TGTCCTCCCTTCTCTTGCTCAGC OBD159_705_707 0.000204132
2 OBD159_711 CTGAGACAAGGCAGGGCAGGTGTTA OBD159_709_711 0.003791936
3 OBD159_715 TTAGATGGATGAAAGAGATGAAAA OBD159_713_715 0.000729495
4 OBD159_719 GCCAAGGGTTCAGAAAGCCCAGG OBD159_717_719 0.00147384
5 OBD159_723 CACCAGCCTTTGTGTTGTCGTCCAAT OBD159_721_723 0.000488261
6 OBD159_727 ACGCAAATGCTTTCCCACAGAATA OBD159_725_727 0.001276989
7 OBD159_731 CCGCATCAGAGATTCCTCAAGTTTGC OBD159_729_731 0.004266748
8 OBD159_735 GGGCAGGGTATCTAAGGCAATGGTTC OBD159_733_735 0.001897525
9 OBD159_739 GAAGCCAGCACTTGGGAGACCAC OBD159_737_739 0.000703029
10 OBD159_743 TTCTGACTCTCTCCCTTTGGTGAG OBD159_741_743 0.001438401
11 OBD159_747 TCCGACCAACCCAGACCAACCTG OBD159_745_747 0.002378528
12 OBD159_751 ATGGTGGTAAACACAGACATCTATCT OBD159_749_751 0.00037646
13 OBD159_755 GGCTTGGGAAATCACTCTAATAGGTC OBD159_753_755 0.002320932
14 OBD159_759 CAAATCTCTCATCTACGCCGTTTCTA OBD159_757_759 0.000257549
15 OBD159_763 TTGAGGCAGGAAGAAAGGTTTATGGC OBD159_761_763 -0.000201451
16 OBD159_767 TTTTCTGCCTCAGCCTCCCAAGTA OBD159_765_767 -0.000807931
17 OBD159_771 AGAGCCAGTCCGAGTTCCAAAAC OBD159_769_771 0.001416613
18 OBD159_775 AGATTCTGTCCCTGGCAACCAAACAC OBD159_773_775 0.000108683
19 OBD159_779 GGAAAATCTAAAAGTAATGGACAAA OBD159_777_779 -0.000946523
20 OBD159_783 CTTGCTTGTTATTCTACATTTCTAT OBD159_781_783 0.000634476
21 OBD159_787 ATTCGGAGTTGAGAGTCCTGGGTCTT OBD159_785_787 0.001606518
22 OBD159_791 CTCCCCACCCTTCTGGAAAAGAG OBD159_789_791 0.000708309
23 OBD159_795 GGTTGGAAGCCTTACGCAGTCTCAAG OBD159_793_795 0.001129047
24 OBD159_799 CTCTCTTGGTGTTTGGAAATCTGTGC OBD159_797_799 0.001893287
25 OBD159_803 AAAACTGAAAGGACGAACCCAGC OBD159_801_803 0.001392556
26 OBD159_807 CAGCCCAGGACCACCAGCGAAGT OBD159_805_807 0.001267325
27 OBD159_811 GACCAGACCAAACCAAACCAACAT OBD159_809_811 -0.00013287
28 OBD159_815 GACCCTGAGCCACAGCAAAGCCT OBD159_813_815 0.002957875
29 OBD159_819 CTAAGTCCAGTAGTATGGTGGCTGTG OBD159_817_819 0.000983784
30 OBD159_823 GCTATGGAGTGTCTCTTTGGGTCTCA OBD159_821_823 0.000764481
31 OBD159_827 GCCTGTCACTCCAATCTGTGGTG OBD159_825_827 0.000329008
32 OBD159_831 AGGCTGTGCTTGGCTGGTTGTGTAAC OBD159_829_831 0
33 OBD159_835 GGAAAGTCCCAGGCTCCAGGAAG OBD159_833_835 0.002689289
34 OBD159_839 GTCCCTGCTCTCAAAGAACTTAGGA OBD159_8379_839 0.000789295
35 OBD159_843 CTGGAAGTGACCTTAGAGATTATC OBD159_841_843 0.001532591
36 OBD159_847 TCCTCAGATGATGTTTCGGCATTTGC OBD159_845_847 0
37 OBD159_851 GGTGACTGACAGCCAAATCCAATGGG OBD159_849_851 -0.001073064
38 OBD159_855 TGGGCTCCAAACACCCGAGGTCAT OBD159_8539_855 0
39 OBD159_859 CTCCCAGAAACCAGACCCACAAAGAG OBD159_857_859 0.001183739
40 OBD159_863 ATCAAGAAAACTACTCACAGGACAGC OBD159_861_863 0.001815264
41 OBD159_867 CAAGTCCTCATCTGTAGAGTCTGGAT OBD159_865_867 0.00089186
42 OBD159_871 AAAGAGACAGAAACAGAGAGGTTA OBD159_869_871 0.00057281
43 OBD159_875 GCAGCCATTACAAAATCACCTTCAGG OBD159_873_875 0.001794869
44 OBD159_879 GCCAGGAAAAGCCTCAGAGTCAC OBD159_877_879 0.002480365
45 OBD159_883 GTGCTCGTCTCACCATCTTCCTG OBD159_881_883 0.001698299
46 OBD159_887 CATCAGGCTTCTGGGAATGGAAAT OBD159_885_887 0.001560892
47 OBD159_891 AAGACAGGGTTGGCAAAGGCAGC OBD159_889_891 0.002874402
48 OBD159_895 TCTCCACTCACTCCCACCCTTGG OBD159_893_895 0.00113627
49 OBD159_899 GCTTTCCTTCTTCCTTATGATGACAG OBD159_897_899 0.001771069
50 OBD159_903 TTGGATAAGAACGAGCAGGTATTGGC OBD159_901_903 0.001898652
51 OBD159_907 GCAAAGACCTACTCCCACCTCCTC OBD159_905_907 0.001697095
52 OBD159_911 CCCAAAGTTTCGGTTCATTAGATTTC OBD159_909_911 0.001506795
53 OBD159_915 AAGGAGAGGGAAAACAGTGGGCAATA OBD159_913_915 0.000946814
54 OBD159_919 AAACGGGTCTCCACGGCACCAAG OBD159_917_919 0.003366899
55 OBD159_923 TGGCAGACGCCTGTAATCCCAG OBD159_921_923 0.001743503
56 OBD159_927 GATTGAACGCCATCTGGTGTGACTGG OBD159_925_927 0.003692609
57 OBD159_931 TCTTATTTCCCAAGGCTCAAAAGC OBD159_929_931 8.95E-05
58 OBD159_935 GTGGTTCAAGGTAGGAAGAGAAAAGC OBD159_933_935 0.001522281
59 OBD159_939 TAACCAGGGTAGCCTTGATGCCAGC OBD159_937_939 0.00052172
60 OBD159_943 GCCACACTGGAACATACCAAGTAAAC OBD159_941_943 0.002045299
61 OBD159_947 TTGCCCGCTATCTTTACTTCAGTTGC OBD159_945_947 0.002404691
62 OBD159_951 ATCAGTGTTTTCTCCTCTCAAATA OBD159_949_951 0.000121861
63 OBD159_955 TACAGTATTTGAGTCACAGGCTGC OBD159_953_955 0.000910382
64 OBD159_959 ATCACCTCCTATGAAGACCTACCTCT OBD159_957_959 0.001773689
65 OBD159_963 GAAAATGAATCCAAGAAAACTCTAT OBD159_961_963 0.000145047
66 OBD159_967 ACACGGTCCCTGACTCAAGATGGTTG OBD159_965_967 9.34E-06
67 OBD159_971 GCACAAACACGATGACACTTCACAGA OBD159_969_971 0.000203749
68 OBD159_975 ACTGTCTGAAGCAATCGGTTCCCCAG OBD159_973_975 0.000150605
69 OBD159_979 AAAGTGCTGGGATTACAGGCGTGA OBD159_977_979 0.002131125
70 OBD159_983 TTCTGTGGAGGACCTGGGAAATACTC OBD159_981_983 0.00250562
71 OBD159_987 CTCTAAGTAAATCCTGGTCATTCCCC OBD159_985_987 0.000695805
72 OBD159_991 TGTTATCAGGACAGCAGTTAGCAGGA OBD159_989_991 -0.000234901
73 OBD159_995 GGAGAAAAGACAAACCAGGGAAAGGG OBD159_993_995 0
74 OBD159_999 TTTGAAATGGAGACATAGCCCAAGGC OBD159_997_999 0.001961012
75 OBD159_1003 CCTTTGCTGGGTATTGACTGGGAGGA OBD159_1001_1003 0.001676635
76 OBD159_1007 GTGGTGTGAGTTCAGGAGGGTTTAGG OBD159_1005_1007 0.0028322
77 OBD159_1011 CCACCGATTTATTGCCCTGTAGGACA OBD159_1009_1011 0.000290704
78 OBD159_1015 GGGACTGAGTGACACAAGGACCATTT OBD159_1013_1015 0.001727135
79 OBD159_1019 ATGAGCCTGGAACATCTGGTGATACC OBD159_1017_1019 2.92E-05
80 OBD159_1023 GCAGCCAATCTTGAGAACTGATGCCC OBD159_1021_1023 0.003000365
81 OBD159_1027 TGGGAGCAGGAGTGGAGGAATAGATT OBD159_1025_1027 0.004030392
82 OBD159_1031 GCGGTCATCAGTGCTGTCATTTCCTG OBD159_1029_1031 0.00143169
表2.a8
   基因
1 SMPD3; rs2863973
2 BCAP29; SLC26A4
3 FBXO16; FZD3
4 ASTN1
5 PLA2G4A; rs4140564
6 NA
7 PTTG1; SLU7
8 CNKSR3; IPCEF1; OPRM1
9 PRKAR2B
10 AK5; rs6695572
11 RHOB
12 FBXW7
13 SBF2
14 NA
15 NEDD4L; rs17064520
16 NA
17 AMPH; FAM183B
18 KIAA1549L
19 C10orf11; rs10509373; rs11593840
20 CHTF8; CIRH1A; SNTB2; rs119465999
21 C18orf42
22 IFT27; rs5750285
23 rs12586774; rs862946
24 NA
25 PRPSAP1; QRICH2; UBALD2
26 rs886037841; rs9810566; TNIK
27 MYO1E
28 ADAM19; NIPAL4; rs1990950; rs199422216; rs199422217; rs370356566; rs375688767; rs775903553
29 LINGO2; rs10812774; rs7851437
30 AMELX; ARHGAP6
31 PIEZO2; rs7228002
32 C10orf11
33 PRSS42; PRSS45; PRSS50
34 ARHGAP20; FDX1
35 MBNL1; TMEM14E; rs185894411
36 NA
37 rs113246091; rs11960179
38 ADCY2; rs11948030; rs13166360; rs17231202; rs17826395; rs17826816; rs34043481
39 ABHD17C; CEMIP; rs11634851
40 MEIS1; rs11692361
41 LINGO2; rs10812774; rs7357773
42 KLRC1; KLRC2; KLRC3; KLRC4; KLRC4-KLRK1; KLRK1; RP11-277P12.6; rs11053781; rs11053802; rs2617167; rs2617170; rs7298732; rs77926410
43 NA
44 NA
45 rs7542939
46 GABARAPL1; OLR1; TMEM52B
47 EMP1; rs1479119
48 ANKRD10
49 DLGAP1
50 POU3F3; rs1005999
51 MYCN
52 ALPK1; TIFA
53 IFNGR1; rs13201877
54 CACNA1E; rs679931
55 MTOR; UBIAD1
56 GYLTL1B; PHF21A
57 RNPC3
58 rs358231
59 KRTAP19-8
60 AMIGO2; SLC38A4
61 LMBRD2; SKP2
62 PTPLAD1; SLC24A1; VWA9; rs11632310; rs12906196; rs4366668; rs6494529; rs7165102; rs7178686
63 PLGLB2
64 HRASLS
65 CLASP1; rs62151096
66 ANXA11; MAT1A; rs10887710; rs1298908; rs2819941; rs3851059; rs7087728
67 CNKSR3; IPCEF1; OPRM1; rs2236256; rs4869818
68 MECOM; rs12491785; rs2901381; rs864309724
69 AK5
70 rs11897825; rs2337901
71 GRM1; SHPRH
72 SLC25A13; rs1060499612; rs746155190; rs763191789; rs80338716; rs80338717; rs80338718; rs80338719; rs80338720; rs879255504
73 DAW1; rs113776284; rs7591163
74 RFTN1
75 PTPRD; rs10120450; rs10120501; rs10121203; rs10758996; rs10815964; rs1434254; rs1836229; rs1975197; rs2053125; rs7048621
76 KRTAP19-8; rs8134605
77 rs4925506
78 TAB2
79 DNAJC6; rs2477786
80 ANKS1B; rs7960581
81 RPS6KA5; TTC7B
82 AVEN; CHRM5; RYR3; rs661968
表2.a9
   探針 基因座
83 ORF15_20_20005082_20006543_20074979_20078974_FR CFAP61; CRNKL1  A20; RIN2; rs1057519885
84 ORF15_22_25694410_25695479_25711627_25712666_FR ADRBK2
85 ORF15_4_152191742_152196830_152216416_152218364_FF FBXW7
86 ORF15_5_39114378_39119150_39147583_39150100_FF FYB; RICTOR
87 ORF15_6_168253924_168260809_168288516_168295264_RF DACT2; rs1473500
88 ORF15_X_134208394_134214384_134247371_134250961_FF CCDC160; PHF6
89 ORF150_2_156262877_156267602_156333728_156335220_FR NR4A2
90 ORF151_1_213954211_213958027_214030463_214032351_RF PROX1
91 ORF151_12_30089465_30094558_30144610_30146709_RR rs11050764; rs4931251
92 ORF151_14_25830955_25834255_25934805_25940195_FF rs12586774; rs862946
93 ORF152_12_82605920_82610130_82624217_82631901_FR METTL25; TMTC2
94 ORF152_3_106246431_106249672_106270924_106284204_FF NA
95 ORF152_6_115981175_115984851_116082282_116083649_RR FRK; NT5DC1; rs1933737; rs1999930; rs3822857; rs6909746; rs868943; rs9488822
96 ORF155_4_22917017_22918108_22970139_22978081_FR NA
97 ORF16_1_76000194_76003911_76083373_76086337_FR ST6GALNAC3; rs12095069
98 ORF16_13_33822756_33828516_33864974_33872117_RR RFC3
99 ORF16_17_4314279_4315337_4363166_4364509_FR ANKFY1; UBE2G1
100 ORF16_2_39607186_39609982_39623225_39627003_FR MAP4K3; TMEM178A
101 ORF16_20_46570710_46574158_46631132_46633823_FF OCSTAMP; SLC13A3; rs847058
102 ORF16_22_25569452_25577394_25694410_25695479_RF ADRBK2; MYO18B
103 ORF16_22_25661627_25666380_25694410_25695479_RF ADRBK2
104 ORF16_5_39119150_39126856_39147583_39150100_RF FYB; RICTOR; rs1060505056
105 ORF16_6_13526281_13531876_13559103_13561354_RR GFOD1; SIRT5
106 ORF16_6_154154477_154163186_154217494_154220454_RR CNKSR3; IPCEF1; OPRM1; rs2236256; rs4869818
107 ORF161_1_229849427_229855718_229869805_229873008_FF GALNT2; rs4925506
108 ORF161_7_112014904_112016980_112124185_112133295_RR DOCK4
109 ORF162_6_46989661_46997140_47060758_47069708_RF GPR110; GPR116
110 ORF163_3_177780034_177784103_177831413_177834825_FF NA
111 ORF166_7_29763050_29768509_29809501_29813015_RR WIPF3; rs850084
112 ORF167_1_229849427_229855718_229908605_229911291_FF GALNT2; rs4925506
113 ORF167_2_195495210_195503375_195555062_195566669_FF SLC39A10
114 ORF168_12_30144610_30146709_30181629_30184999_RR NA
115 ORF169_15_95109397_95110442_95161353_95168020_RF NA
116 ORF17_12_14122272_14125684_14156567_14160836_RF GRIN2B
117 ORF17_2_66361342_66362770_66462513_66470757_FF MEIS1; rs11692361; rs7596219
118 ORF17_20_46568090_46570710_46643075_46649811_FR SLC13A3
119 ORF17_3_64194265_64195323_64225983_64228797_FR PRICKLE2
120 ORF17_4_105415477_105417649_105457783_105460154_FF PPA2; rs1057517679; rs1057517680; rs138215926; rs139076647; rs146013446; rs546693824; rs772083375; rs77928427
121 ORF17_5_162413257_162414861_162467630_162474185_RF rs587777363; rs7718928
122 ORF17_6_82564978_82571469_82630737_82633712_FR TPBG; rs1369867
123 ORF170_1_58212403_58221374_58250279_58252343_RF DAB1; rs527409
124 ORF170_5_132790667_132795213_132845490_132849804_RF rs39692; GDF9; SHROOM1; SOWAHA
125 ORF171_18_11015786_11021011_11118494_11119843_RR PIEZO2
126 ORF172_11_75842855_75846190_75861382_75864724_RF UVRAG
127 ORF173_14_39721868_39724679_39792290_39806170_FR rs148431766; rs17109786
128 ORF174_13_110131405_110134324_110153678_110157618_FR COL4A1; rs11617955; rs641862; rs672601348
129 ORF174_2_209659511_209662054_209697743_209702208_FF MAP2
130 ORF175_19_29325557_29328725_29376361_29378170_RR UQCRFS1; VSTM2B
131 ORF175_3_69167897_69172562_69218117_69221087_FR FRMD4B; LMOD3
132 ORF18_1_107900199_107901840_107960595_107963096_RR VAV3; rs2801219; rs345299; rs4915077
133 ORF18_1_8397345_8398792_8423193_8424500_RF RERE; rs301806; rs301807
134 ORF18_11_49136317_49141722_49212875_49219818_FR FOLH1; TRIM64C
135 ORF18_14_89952946_89954082_89986309_89987695_FF EFCAB11; TDP1
136 ORF18_3_24254159_24259126_24320266_24324992_FF THRB; rs113700287; rs1158265; rs12485694; rs1505283; rs1505297; rs1505298; rs1505307; rs1868575; rs2167115; rs7610039; rs7610222; rs7622481; rs7640580; rs826230; rs826231; rs826236; rs826238; rs826240; rs862247; rs869784; rs869785; rs9310736; rs9830674
137 ORF18_5_88780146_88782265_88885645_88890401_RF MEF2C; rs1085307051; rs114694170; rs11951031; rs11955542; rs11958689; rs12515983; rs12521522; rs17558256; rs17560407; rs17560451; rs3047819; rs3850651; rs3850653; rs397514655; rs397514656; rs4521516; rs545185248; rs61104616; rs62380364; rs700585; rs797045053; rs869312698; rs876661308
138 ORF18_6_137232223_137235679_137341897_137343885_RF IFNGR1; rs13201877
139 ORF180_14_106693397_106698909_106725269_106729795_RF NA
140 ORF181_5_148931403_148934917_149013571_149016721_RR SH3TC2; rs80338933; rs80338934; rs80338935; rs80338936; rs80338937; rs9687065
141 ORF183_3_45968082_45972062_46021458_46028558_RF FYCO1; XCR1
142 ORF183_8_52230322_52233827_52319467_52326208_RR ST18
143 ORF186_10_89827266_89829504_89863078_89864649_RR KIF20B
144 ORF186_2_198037606_198046520_198099686_198102962_RR PLCL1
145 ORF187_2_102980783_102983000_103034107_103047709_RR NA
146 ORF187_6_157897501_157902533_158001619_158004030_RF SNX9; SYNJ2
147 ORF188_6_30104839_30106896_30143621_30146632_RR TRIM31; TRIM40
148 ORF19_20_46511970_46518882_46567001_46568090_RF OCSTAMP; SLC13A3; ZNF334
149 ORF19_8_86980479_86986149_87043788_87045089_RR CNBD1; rs41486944
150 ORF19_8_89837286_89838355_89905359_89910373_FR OSGIN2
151 ORF190_7_42842614_42843656_42886026_42890585_FF C7orf25
152 ORF191_2_102924054_102927148_102983000_102995309_FR TMEM182
153 ORF191_3_168579832_168593354_168619477_168632678_RF NA
154 ORF191_5_6223946_6226870_6298491_6302848_FR NA
155 ORF192_10_12596194_12598368_12616738_12619998_RF CAMK1D
156 ORF193_5_90129888_90142322_90153362_90157668_RF NA
157 ORF193_6_155189636_155191926_155219095_155222285_RR TFB1M; TIAM2
158 ORF195_20_11971793_11975460_11994892_11999282_FR BTBD3; rs16992846
159 ORF196_1_229821816_229824593_229859020_229862315_RR GALNT2; rs4925506
160 ORF197_1_66151966_66159635_66218811_66223865_FR PDE4B; rs10454453; rs486438; rs490094; rs567279; rs6588190
161 ORF197_13_110131405_110134324_110146402_110150942_FR COL4A1; rs641862; rs672601348
162 ORF197_15_69259199_69263452_69320948_69322275_RR GLCE; PAQR5
163 ORF197_4_22994756_23003981_23065929_23067873_FR rs358231
164 ORF198_9_28270698_28275294_28314155_28333777_RF LINGO2; rs10812774; rs7357773
表2.b1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
83 15; 17; 104; 175 1; 1; 1; 1; 1; 1; 4; 4 0.335307856; 0.346011739; 0.350975055; 0.359834557; 0.067095696; 0.05179789; 0.096861772; 0.075450093
84 110 1; 4 0.055848211; 0.190296804
85 143 3; 2 0.107765005; 0.041422991
86 10; 8 2; 2; 2; 2 0.049739473; 0.05651991; 0.033505489; 0.038320555
87 42 1 0.320791853
88 26; 38 1; 1; 1; 1 0.375314357; 0.373699919; 0.340322106; 0.325888812
89 9 1 0.268692312
90 53 1; 2 0.261255041; 0.272683217
91 NA NA NA
92 NA NA NA
93 9; 27 1; 1; 2; 1 0.255358235; 0.268692312; 0.197546356; 0.37173223
94 NA NA NA
95 28; 28 3; 2; 2; 1 0.071800115; 0.219149094; 0.204457601; 0.369266824
96 NA NA NA
97 45 5; 5  0.022343156; 0.028833151 
98 17 1; 2 0.350975055; 0.126473611
99 27; 27 1; 1 0.37173223; 0.37173223
100 21; 58 2; 1; 2; 1 0.149991246; 0.37425716; 0.271314317; 0.210195578
101 66; 117 1; 1; 2; 3 0.193835981; 0.169430739; 0.106169317; 0.143969124
102 110; 75 1; 4; 1 0.055848211; 0.190296804; 0.130607391
103 110 1; 4 0.055848211; 0.190296804
104 10; 8 2; 2; 2; 2 0.049739473; 0.05651991; 0.033505489; 0.038320555
105 60; 32 1; 1 0.199487628; 0.35529211
106 163; 163; 140 4; 2; 4; 2; 4; 2 0.117375195; 0.022678142; 0.117375195; 0.022678142; 0.158806697; 0.045194146
107 44 4; 3 0.063857117; 0.169607427
108 58 1 0.210195578
109 15; 9 1; 1 0.335307856; 0.255358235
110 NA NA NA
111 13 1 0.314642613
112 44 4; 3 0.063857117; 0.169607427
113 81 3; 3 0.227770757; 0.222648484
114 NA NA NA
115 NA NA NA
116 60 1; 2 0.22379944; 0.259153243
117 57 4; 2 0.110951788; 0.26588291
118 117 2; 3 0.106169317; 0.143969124
119 41 1; 2 0.325868449; 0.271883499
120 19 1 0.362286681
121 NA NA NA
122 22 1 0.372324987
123 11 1 0.288260522
124 2; 27; 27; 30 2; 1; 1; 1 0.001770535; 0.37173223; 0.37173223; 0.363021342
125 67 1; 1 0.189085999; 0.164740427
126 14 1; 1 0.325643034; 0.337131196
127 NA NA NA
128 98 2 0.1586416
129 60 5; 7 0.05512946; 0.009185497
130 54; 120 1; 1 0.255792527; 0.040862114
131 151; 84 1; 2; 1; 2 0.014886343; 0.032692527; 0.120373828; 0.181549809
132 31 1 0.366789724
133 16 2; 1 0.104530159; 0.353547066
134 25; 22 3; 4; 1; 2 0.05677955; 0.016055763; 0.372324987; 0.173304212
135 81; 71 1; 2; 1; 2 0.130826821; 0.192025586; 0.170848338; 0.226583412
136 14 3; 2  0.013899641; 0.096260668 
137 28 1 0.373281001
138 93 2 0.17427462
139 NA NA NA
140 27 1 0.374553651
141 7; 2 1; 1 0.227740664; 0.080664005
142 78 2; 4 0.222357541; 0.186212358
143 22 3 5.07E-02
144 27 1; 2 0.374553651; 0.212429916
145 NA NA NA
146 50; 39 1; 1 0.255769837; 0.320372604
147 49; 30 1; 1 0.261686551; 0.363021342
148 66; 117; 15 1; 1; 2; 3; 1 0.193835981; 0.169430739; 0.106169317; 0.143969124; 0.346011739
149 20 1 0.366490901
150 14 1; 2 0.325643034; 0.096260668
151 34 1 0.346365974
152 27 2; 3 0.197546356; 0.077717327
153 NA NA NA
154 NA NA NA
155 41 1 0.309016356
156 NA NA NA
157 42; 42 1; 1 0.303213711; 0.303213711
158 33 1 0.360592644
159 44 4; 3 0.063857117; 0.169607427
160 17 3; 2 0.023054538; 0.126473611
161 98 2 0.1586416
162 85; 20 1; 1 0.096152866; 0.372098641
163 NA NA NA
164 20 6; 4 7.69e-05; 0.007618647
表2.b2
   FDR_HyperG Percent_Sig logFC AveExpr
83 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.67; 6.67; 5.88; 5.88; 0.96; 0.96; 2.29; 2.29 -0.792992048 -0.792992048
84 0.375519541; 0.376115439 0.91; 3.64 -0.71786538 -0.71786538
85 0.375519541; 0.376115439 2.1; 1.4 -0.868846993 -0.868846993
86 0.375519541; 0.376115439; 0.375519541; 0.376115439 20; 20; 25; 25 -0.668469792 -0.668469792
87 0.375519541 2.38 -0.782974344 -0.782974344
88 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.85; 3.85; 2.63; 2.63 -0.796548184 -0.796548184
89 0.376115439 11.11 -0.736621417 -0.736621417
90 0.375519541; 0.376115439 1.89; 3.77 -0.788346188 -0.788346188
91 NA NA -0.716810383 -0.716810383
92 NA NA -0.781758026 -0.781758026
93 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 11.11; 7.41; 3.7 -0.628076664 -0.628076664
94 NA NA -0.720386221 -0.720386221
95 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.71; 7.14; 7.14; 3.57 -0.757155557 -0.757155557
96 NA NA -0.718991975 -0.718991975
97 0.375519541; 0.376115439  11.11; 11.11  -0.947138659 -0.947138659
98 0.375519541; 0.376115439 5.88; 11.76 -0.72720363 -0.72720363
99 0.376115439; 0.376115439 3.7; 3.7 -0.745245961 -0.745245961
100 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.52; 4.76; 3.45; 1.72 -0.707334239 -0.707334239
101 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.52; 1.52; 1.71; 2.56 -0.978256481 -0.978256481
102 0.375519541; 0.376115439; 0.376115439 0.91; 3.64; 1.33 -0.708665991 -0.708665991
103 0.375519541; 0.376115439 0.91; 3.64 -0.666227638 -0.666227638
104 0.375519541; 0.376115439; 0.375519541; 0.376115439 20; 20; 25; 25 -0.733776113 -0.733776113
105 0.376115439; 0.376115439 1.67; 3.12 -0.624247879 -0.624247879
106 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.45; 1.23; 2.45; 1.23; 2.86; 1.43 -0.745666862 -0.745666862
107 0.375519541; 0.376115439 9.09; 6.82 -0.748947194 -0.748947194
108 0.376115439 1.72 -0.632299188 -0.632299188
109 0.375519541; 0.375519541 6.67; 11.11 -0.75272274 -0.75272274
110 NA NA -0.622972468 -0.622972468
111 0.375519541 7.69 -0.877638416 -0.877638416
112 0.375519541; 0.376115439 9.09; 6.82 -0.732135681 -0.732135681
113 0.375519541; 0.376115439 3.7; 3.7 -0.72169935 -0.72169935
114 NA NA -0.741191529 -0.741191529
115 NA NA -0.682677123 -0.682677123
116 0.375519541; 0.376115439 1.67; 3.03 -0.845149985 -0.845149985
117 0.375519541; 0.376115439 7.02; 3.51 -0.80602165 -0.80602165
118 0.375519541; 0.376115439 1.71; 2.56 -0.690428613 -0.690428613
119 0.375519541; 0.376115439 2.44; 4.88 -0.684279062 -0.684279062
120 0.375519541 5.26 -0.756728555 -0.756728555
121 NA NA -0.772400821 -0.772400821
122 0.375519541 4.55 -0.752005992 -0.752005992
123 0.375519541 9.09 -0.776274717 -0.776274717
124 0.082088441; 0.376115439; 0.376115439; 0.376115439 100; 3.7; 3.7; 3.33 -0.739742657 -0.739742657
125 0.375519541; 0.376115439 1.49; 1.49 -0.629601593 -0.629601593
126 0.375519541; 0.376115439 7.14; 7.14 -0.77209146 -0.77209146
127 NA NA -0.731244645 -0.731244645
128 0.375519541 2.04 -0.806448864 -0.806448864
129 0.375519541; 0.275564898 8.33; 11.67 -0.634548613 -0.634548613
130 0.375519541; 0.375519541 1.85; 0.83 -0.715276704 -0.715276704
131 0.375519541; 0.376115439; 0.375519541; 0.376115439 0.66; 1.32; 1.19; 2.38 -0.658137917 -0.658137917
132 0.375519541 3.23 -0.717405198 -0.717405198
133 0.375519541; 0.376115439  12.5; 6.25  -0.83682961 -0.83682961
134 0.375519541; 0.376115439; 0.375519541; 0.376115439 12; 16; 4.55; 9.09 -0.663906528 -0.663906528
135 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.23; 2.47; 1.41; 2.82 -0.673376752 -0.673376752
136 0.375519541; 0.376115439 21.43; 14.29 -0.781589397 -0.781589397
137 0.375519541 3.57 -0.785820105 -0.785820105
138 0.375519541 2.15 -0.810473195 -0.810473195
139 NA NA -0.623437638 -0.623437638
140 0.375519541 3.7 -0.745678102 -0.745678102
141 0.376115439; 0.376115439 14.29; 50 -0.665598854 -0.665598854
142 0.375519541; 0.376115439 2.56; 5.13 -0.833911882 -0.833911882
143 0.376115439 13.64 -0.741040211 -0.741040211
144 0.375519541; 0.376115439 3.7; 7.41 -0.742388687 -0.742388687
145 NA NA -0.635385214 -0.635385214
146 0.376115439; 0.376115439 2; 2.56 -0.777208118 -0.777208118
147 0.376115439; 0.376115439 2.04; 3.33 -0.624302982 -0.624302982
148 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.376115439 1.52; 0.85; 1.71; 20; 6.67 -0.631933144 -0.631933144
149 0.375519541 5 -0.794820514 -0.794820514
150 0.375519541; 0.376115439 7.14; 14.29 -0.787561896 -0.787561896
151 0.376115439 2.94 -0.685208953 -0.685208953
152 0.375519541; 0.376115439 7.41; 11.11 -0.631706124 -0.631706124
153 NA NA -0.717890738 -0.717890738
154 NA NA -0.784153786 -0.784153786
155 0.376115439 2.44 -0.847700439 -0.847700439
156 NA NA -0.628772132 -0.628772132
157 0.376115439; 0.376115439 2.38; 2.38 -0.752750371 -0.752750371
158 0.375519541 3.03 -0.734645954 -0.734645954
159 0.375519541; 0.376115439 9.09; 6.82 -0.852475095 -0.852475095
160 0.375519541; 0.376115439 17.65; 11.76 -0.753556643 -0.753556643
161 0.375519541 2.04 -0.86271955 -0.86271955
162 0.376115439; 0.376115439 1.18; 5 -0.636957952 -0.636957952
163 NA NA -0.778465363 -0.778465363
164 0.008046243; 0.242844385 30; 20 -0.727431725 -0.727431725
表2.b3
   t P值 adj.P.Val B FC FC_1 LS
83 -6.315807727 0.0000388 0.000427828 2.235197344 0.57714589 -1.732664163 -1
84 -5.537887222 0.000130736 0.00175879 1.067378001 0.607996372 -1.644746656 -1
85 -6.889033657 0.0000169 0.000246775 3.094928994 0.547584307 -1.826202809 -1
86 -6.947071281 0.0000159 0.000427061 3.233099187 0.629173673 -1.589386275 -1
87 -5.985260916 0.000064 0.000606153 1.718491824 0.581167389 -1.720674661 -1
88 -4.450496459 0.000802381 0.00624043 -0.792357296 0.57572502 -1.736940319 -1
89 -6.21630455 0.0000458 0.00086 2.14521907 0.600143156 -1.666269105 -1
90 -14.15645318 0.00000000802 0.00000491 10.80928787 0.579007448 -1.727093499 -1
91 -4.824893047 0.000417375 0.002330466 -0.216233165 0.608441143 -1.643544345 -1
92 -7.796152973 0.00000494 0.000109809 4.36473782 0.58165757 -1.719224594 -1
93 -5.179949705 0.000233322 0.002635975 0.472450904 0.647038443 -1.545503224 -1
94 -7.988184508 0.00000395 0.00017566 4.657828504 0.606934939 -1.647623058 -1
95 -11.05181894 0.000000122 0.000011 8.14111358 0.591661712 -1.690154998 -1
96 -7.538446204 0.00000709 0.000252002 4.059757678 0.607521775 -1.646031535 -1
97 -9.857113647 0.000000424 0.0000234 6.881364823 0.518660117 -1.928044913 -1
98 -7.456049368 0.00000791 0.000271777 3.947366204 0.604073653 -1.655427272 -1
99 -8.637988348 0.00000176 0.000106054 5.477905517 0.596566156 -1.676260026 -1
100 -6.714567946 0.0000217 0.000290609 2.838087003 0.612450759 -1.632784327 -1
101 -10.76014022 0.000000164 0.0000132 7.845457749 0.507592803 -1.970083094 -1
102 -9.426224608 0.000000704 0.0000597 6.407657613 0.611885666 -1.634292246 -1
103 -6.576257223 0.000027 0.00060633 2.690445925 0.630152259 -1.586918061 -1
104 -9.506988773 0.000000624 0.0000297 6.486427981 0.601327935 -1.662986103 -1
105 -4.384389265 0.000900527 0.00678304 -0.910115349 0.648757907 -1.541407033 -1
106 -5.056523908 0.000282775 0.001751743 0.184531457 0.596392135 -1.67674914 -1
107 -13.73693967 0.0000000108 0.00000294 10.55338696 0.595037628 -1.680565991 -1
108 -7.655786319 0.00000607 0.0002294 4.218289153 0.64514744 -1.550033277 -1
109 -8.225011167 0.00000286 0.0000771 4.928493509 0.593482445 -1.684969807 -1
110 -5.179107163 0.000233645 0.002638339 0.471029649 0.649331693 -1.540044959 -1
111 -7.390325566 0.00000846 0.000155288 3.809994153 0.544257612 -1.837365209 -1
112 -7.181478305 0.0000112 0.000187721 3.51616598 0.602012071 -1.661096262 -1
113 -10.8736462 0.000000146 0.0000123 7.961387425 0.606382763 -1.649123393 -1
114 -5.848734747 0.0000802 0.001260075 1.569399495 0.598245055 -1.671555815 -1
115 -8.355041155 0.00000249 0.00013163 5.127022404 0.623008122 -1.60511551 -1
116 -4.545515013 0.000680402 0.005586089 -0.623936608 0.556652936 -1.796451498 -1
117 -11.30872752 0.0000000948 0.0000095 8.395527795 0.571956904 -1.748383477 -1
118 -7.393713894 0.0000086 0.000287838 3.861747456 0.619669724 -1.613762883 -1
119 -11.311488 0.0000000981 0.0000182 8.378200295 0.62231673 -1.606898788 -1
120 -12.5874418 0.0000000288 0.00000502 9.584177076 0.591836855 -1.689654828 -1
121 -11.17482418 0.000000108 0.0000102 8.263613593 0.585442416 -1.708109923 -1
122 -4.89393108 0.000371361 0.002140728 -0.096068082 0.593777367 -1.684132902 -1
123 -8.815642251 0.00000139 0.0000494 5.669027027 0.583872506 -1.71270267 -1
124 -8.584546191 0.00000188 0.00011081 5.412348602 0.598846163 -1.669877945 -1
125 -4.978576007 0.000325767 0.003332827 0.13004571 0.646354884 -1.547137685 -1
126 -7.589537718 0.00000663 0.000241503 4.129003543 0.585567967 -1.707743688 -1
127 -7.520101573 0.00000711 0.000138445 3.98969451 0.602384 -1.660070653 -1
128 -5.965290044 0.000066 0.00061846 1.686778266 0.571787559 -1.748901289 -1
129 -5.634803379 0.000112106 0.001578376 1.22537271 0.644142321 -1.552451946 -1
130 -3.308889367 0.006249188 0.01792273 -2.96908133 0.609088299 -1.641798079 -1
131 -5.942956947 0.0000694 0.001140129 1.718846375 0.633695679 -1.578044531 -1
132 -11.02081164 0.000000126 0.0000112 8.110031497 0.608190338 -1.644222109 -1
133 -8.363302513 0.0000024 0.0000692 5.105530721 0.559872564 -1.786120742 -1
134 -6.668910488 0.0000236 0.00055461 2.827829885 0.631166908 -1.584366968 -1
135 -5.397162973 0.000163819 0.002062862 0.835607994 0.627037334 -1.594801372 -1
136 -7.804152614 0.00000489 0.000109148 4.375462026 0.581725561 -1.719023654 -1
137 -11.62912195 0.0000000696 0.00000801 8.705214587 0.580022148 -1.724072096 -1
138 -14.01750686 0.00000000857 0.00000267 10.77710333 0.570194807 -1.753786579 -1
139 -4.821038346 0.000424616 0.004001789 -0.141536918 0.649122362 -1.540541597 -1
140 -8.509898562 0.00000201 0.000062 5.290735411 0.596387489 -1.676762203 -1
141 -8.40172753 0.00000235 0.000126547 5.185567401 0.630426964 -1.586226569 -1
142 -9.175780457 0.000000937 0.0000711 6.119618276 0.561006005 -1.782512115 -1
143 -6.644042082 0.0000244 0.000568491 2.791073734 0.598307805 -1.671380502 -1
144 -5.023846785 0.00030207 0.003156555 0.20749253 0.597748833 -1.672943459 -1
145 -7.558352653 0.00000691 0.000248079 4.086777794 0.643768899 -1.553352455 -1
146 -6.725563218 0.0000217 0.000527303 2.911241487 0.583494872 -1.71381112 -1
147 -7.603146606 0.00000651 0.000238774 4.147390992 0.648733128 -1.541465908 -1
148 -6.513707717 0.0000295 0.000644318 2.597017253 0.645311149 -1.549640049 -1
149 -8.946875037 0.00000119 0.0000444 5.828167604 0.576414881 -1.734861527 -1
150 -8.928306451 0.00000125 0.0000853 5.828333194 0.5793223 -1.726154855 -1
151 -5.036982396 0.000295538 0.003107408 0.229913584 0.621915745 -1.60793485 -1
152 -5.175798027 0.00023492 0.002647023 0.465446654 0.645412702 -1.549396219 -1
153 -7.239266686 0.0000106 0.000327941 3.647395871 0.607985685 -1.644775566 -1
154 -6.560265983 0.0000276 0.00061648 2.666612596 0.580692463 -1.722081935 -1
155 -8.230893339 0.00000291 0.000144892 4.970072391 0.555669732 -1.799630146 -1
156 -6.837788953 0.0000185 0.000474048 3.075156549 0.646726606 -1.546248432 -1
157 -10.206704 0.0000003 0.000036 7.264001976 0.593471078 -1.685002078 -1
158 -10.09656308 0.000000327 0.00002 7.144474465 0.600965487 -1.663989066 -1
159 -16.30777411 0.00000000152 0.00000115 12.43865494 0.553833761 -1.805595959 -1
160 -5.619316939 0.000113274 0.000903523 1.128422057 0.593139501 -1.68594403 -1
161 -6.034736926 0.0000593 0.000574116 1.796815874 0.549914964 -1.818462972 -1
162 -6.502102235 0.00003 0.000651284 2.579621802 0.643067484 -1.555046749 -1
163 -7.815132055 0.00000482 0.000108145 4.39016783 0.582986603 -1.715305282 -1
164 -6.076430002 0.0000557 0.000548855 1.862549761 0.603978155 -1.655689021 -1
表2.b4
      探針序列 探針位置
偵測到 之環 60 mer Chr
83 sAD AATGTTACTTATTATGATTATTAGATAATCGAAAAGGGGCCCTTTAGAACCCAAGGAAAA 20
84 mAD ATTCTTTTAAACCTAAAATTAGACTGCTTCGAACTTTTGTTCATATCGTTATTCCCCCAA 22
85 sAD AGCAATATGTTTTTAAGATTTATCCTCATCGATGAATCTTACAAAAGAAAATACAGAGTT 4
86 mAD TATTTGCTAAAGAGATAATTCAGTGTTTTCGAAAAAAAATGGCCTCCTAGATTTTGTTTA 5
87 sAD TATAATACCAGTATTTTCTCAAATAGAATCGATTTTTTTCACATCAACGTTACACCAAAA 6
88 mAD GAAATGAGCCAATAATTTTTTTTTTTTTTCGATTAGCAATAATGATAATAACAAGGGTGA X
89 mAD GGGCTAACTTTATATTTTATAAATGTAGTCGATCTTCGTTTGAAACACAAGGTCTATCAC 2
90 mAD CTATAAAGTGATGATTTCTGAGATCTATTCGAGTGACTTAGTGATCCTGGGTATACACCC 1
91 sAD ATGGTAAGTTTTGGGAATTCAAAGAACCTCGATTCTCAGCTATATCCTTAATACTGGAAG 12
92 sAD GAATTATCAAATTATATTCCAGGTTTGTTCGATCATAAAGTTTGTAGGTTTGTAGAGCTG 14
93 mAD AGGACAGAGTTTCAGAGTAAAATTTAATTCGAAAAACAAAAATAATAAATGCAATATTGA 12
94 mAD ATTCACATAAAAAACTTTTTTGTGAACATCGAGTAAGTTCAAAACCCAACAAGGTGAATA 3
95 sAD TTGTCTTTGCTGAGGAATCTCTCATAATTCGATTCTGAGTGAGGCTAAAAGCCACTGGAA 6
96 mAD AAATTTCTGTAATAAAATGGGAGAAATGTCGAGTTGTTTCCAATAATTTTAAAAGATGGC 4
97 sAD TGCTCTTTTAGGATAGCTTGAAGTAATTTCGAAAGAAAGAGAAGTGAAAGTCTCTCTTTG 1
98 mAD GCAATTCATATAGTCTAAAAAATTTTAATCGATTGATTGTAGCTCAAACTGTAGAAATAG 13
99 mAD ATAGCCTAAAATAATGTTTTCAGTATTGTCGAATCTTTCCAATAAATTTGATATGTTTAC 17
100 sAD TCTTTTCTGTGGTTAAATTTTATAAGGATCGATTCAGCTGGGGAAAAATGAAAATAACAA 2
101 sAD GTAGCTGATTCAGTGGTGTTTATAAAGATCGATAGTTGCTTTGTTCTTCTTGTCTATGGT 20
102 mAD ATTCTTTTAAACCTAAAATTAGACTGCTTCGAGAGCCTCATAGATCTCTCTGAGGTACAG 22
103 mAD ATTCTTTTAAACCTAAAATTAGACTGCTTCGACAAATTTATGATGCCTACATCATGAAGG 22
104 sAD TAAACAAAATCTAGGAGGCCATTTTTTTTCGAAATATAATGTAGGAATATTAAAGAAAAT 5
105 mAD GGAACTATTACTTAAACTCTTAAACTCTTCGACATGATTAAGGTATTTCCCTTTTTCTCT 6
106 sAD TTATATTGGAAATCTGTTTCAACAATAATCGATTCAGCATAAAATAAATGCAAATGAAAG 6
107 sAD AACCGGTTTTGTCACAAACATTGAAAAATCGAAGAATGAATGGTGATGAGGAGATGTTTA 1
108 mAD TCTTTTCTTCCTTTTCTCTTTCTTCCTTTCGACTATTTTATTTTTTGTAGAGACGAGATC 7
109 sAD TTGGAAAAGGTAAATTGTGTTTTGTAAATCGAACATCAGGTCAGAATTCCAAAGGGGCGT 6
110 mAD GATTCAGAATGTCTAGTATTTTATTCAATCGATTGATTTTTCCAAAATCACTGCTTCAAA 3
111 sAD ACCATATGGTGACTTTATCTTTACTCCTTCGAGGGGAACTATTAAATATGAGTTAGGGTT 7
112 sAD AACCGGTTTTGTCACAAACATTGAAAAATCGATTTTCATTCTCAATGAATGTTGATCATC 1
113 sAD AGACTGGATCCGTCACTTTAGAACAGACTCGAGATTATCAGTAAGCTCTAGGGAAACTAG 2
114 mAD CTTCCAGTATTAAGGATATAGCTGAGAATCGAAGTCTCAGCTGAGGGATTACTTCTTCAG 12
115 mAD TCATTTTATCTGTCGTATCAAGAGCAATTCGACTGAGATGTCTGAAAGCCTAAAATATAA 15
116 mAD TGACACAGTGTAGATGTTTAATATATATTCGAGAATGTATATGGAAAGGCAGAGGAGCTA 12
117 sAD TTAATTCTTCCATATCTAAGCCTCTTTGTCGAAGAATATCTCTACTCGGCTGTAAATAAT 2
118 mAD CACCATTGCAAAGTTGAAAAATCGTATGTCGAGACATACTTATGAGCACCTACTATGTGC 20
119 mAD GCATTTTTATGAAATTAAATGTCCGTATTCGAAATAAAGCACAAGTGACTCCTTTCCTCA 3
120 sAD AATTCCATCTCAATTATAATTTTTTAACTCGATCTGCGATTGTTTGAATCTGCAGATGCA 4
121 sAD GATAATCAAAAAACATTTGTTGAATAGATCGAGTCCATGTCCAGTTGTTAATTCAATGTG 5
122 sAD GCTAGAATAATTACTATAGTCATGTTTTTCGAAATTAGTTACTTTAAGAAACCCCATATA 6
123 sAD TCTGTCTTTTTCTCAAGCAGGAAACATTTCGAGTGAGGAATTAAATTCATAGAGGTAACC 1
124 mAD AGTTTTTAATGTCAAATATGATATACAGTCGAAACAGTTATTTACTTTCAACTCTCTCAT 5
125 mAD TTCGTGTTTATTGTTTTCCATAAGAAATTCGATTGCATCTAACCTTTGGATCTCATTCAA 18
126 mAD AATTCTTCCCTAAGGATATTTATTAACTTCGATTTAGAAGTTACTTCCTTGTGGCCCTGG 11
127 sAD GTTGACTCTTAGAACAACGGAAAAACTATCGAAAATGGGTTCTGTTTCAAATACATGGAA 14
128 sAD TTTAAACTGATAAGAACAGATATTACCCTCGAATTATTGCAACAACCTGTTAATCTGGTG 13
129 mAD GAGATTTTCTTAAGACGGTAATTCTTAATCGAGTTACTCAAAGACCAAGGGGCTTAAAAA 2
130 sAD CTTAAAGCTGTCTAAATTTTATCTTAGTTCGAGGCCCTTTCAGGACTCTTTTCCTGGGGA 19
131 mAD ATTGTGACAATCACATTTTAAGTACTCTTCGAAAGAGAATGATCTGAACATTTTAGGATG 3
132 sAD TGTTAATTTTCAGTAGGTTTCCTAAGTGTCGAGCTTCCATTTTCTCTCTGACTTCACGTT 1
133 sAD TGTCAATTTTCAATATAATTCATACAGTTCGACTTTCACTACGACTCTGAGGGAGGTTCT 1
134 mAD CATATGAGAAAGTGGAAAAGATTTAAAATCGAATGAAAAATGAAATCATGCTATGCCTTT 11
135 mAD ATTACTAGTTTATTATACAGTTTGGACCTCGAGGGACAGCAGTAAATTTACAACCCAAAG 14
136 sAD AACTCTTCCATAAAGATTTATCAAAAATTCGATTTTATTCATTTTATTTTGATGTTCCCA 3
137 sAD GTCTGGCATTGTGGAATACTCAATTACATCGAAAAAAAAAAGAAAAAGAAAAAAGAAAAA 5
138 sAD TGTTTATCTCAAAAGAAGCTCAGAAAACTCGATTTTTAAGAGTCAAAGATTTTGATTTAA 6
139 mAD CTCATCTTTGTTAATTCAGATCTATTTTTCGAAAGTATTTAGCAGGTCATGAAACACAAA 14
140 sAD TACATATAGCAAGATAGAAGAAATAACTTCGAAAAGATTTTGATGTTTTGTTTATAAAGA 5
141 mAD GTTTCTTTTTAATTCTTCATAATACCCTTCGACCTTGGTTCTCTCCCTTTCTAGGGCTTG 3
142 mAD TCTCAAATATACTTATAAACAAAAGGGTTCGATGCATAAATATGCATCTATAATATGTTT 8
143 mAD GTATATATATATATATATATATATATGATCGAATGGCAGCTCTACTTTCATTTCCTTAAG 10
144 mAD GAGTATTTAAGATAGGTGCCTATTATCCTCGATTATCTCTTTATGACGTTTATTAGACAA 2
145 mAD AAAAAACCTTTATAAAGAGAAGAGAAAATCGATTTCATTCTTTTAAGCTTTCCCAACACT 2
146 mAD TATTTATTTTTATCATAAGCCATGTTGTTCGATTATTGTTATTATTATTCTTTGAGACAG 6
147 mAD ATTTGCTGCCCCTACAGGGCAGCAGGTTTCGACTATTTTCTAGATTTCAACTTGTCTTTT 6
148 mAD GCTTACTCAGAACTTAAAAATTTCATAATCGAATACTCTTCTCTGATGCTGAATTTTATA 20
149 sAD CCTGAGTTGGTGAATTTTGTATGCTTTCTCGATGTTTCTAAAAACTCATTATTTCTTTAG 8
150 mAD ACCAAGCAGAACTGTATTTAAAACAAATTCGAAGAAAAAGTAGATTTTTATTACTCAAAA 8
151 mAD TCTTCAATAACAGTATTTCTAAAATGTTTCGAATGTCATCAATGTATGTATTAAGTGAGT 7
152 mAD TCACACTAATTTGTTAAATGCAAGTTTATCGATTTCACCAAGTTTGCAAAAGATTCTGTG 2
153 mAD TTTGGATGTGTCATAATCTACTTAAAATTCGATACTTATCTTTACAAAACGCAAGAATAA 3
154 mAD TATCTAGATGTAGGTATATATTTATCTATCGATATCTCTGTTTTCTTTTGACTGGTGGTT 5
155 mAD TTTTCACTCAACTTTCACTGGAGATTTATCGACAAAATAAATGTAGTAGAATTTCTTTGA 10
156 mAD TTCACACAAGATAGAAAATCATTAAAACTCGAGGAGAACCTTCTAATAAGAGATGATCAA 5
157 mAD ATAATGTGTAATTCACCTTTATGTACCTTCGAAGTTAGTGTCAGTGGTCAACTTCTCCCG 6
158 sAD AATTCTTCATCCTTCCTTACATGTGTTATCGAAAAGACAGGTATTTGCATGATTTTTTTT 20
159 sAD TTCCTTCTTAATCAATTCAAGAGCATGTTCGATTTATAACAAAAATAAACACTGTAGAAA 1
160 sAD TTGTAAAGTGCTATAGATAATAGGATTTTCGATAGAGTTAAATACATTTTGGTTGGATGG 1
161 sAD TTTAAACTGATAAGAACAGATATTACCCTCGAAATGTAGTAAGTAAAACCATAAAACTTT 13
162 mAD CATTTTTAAAAAACTCCACTTATCACATTCGAATATTTTCCGCCGACAAGGCCTTTTGGC 15
163 sAD GTAAAAACAAAGCAAATTCTTCAAAATTTCGAATGAATAAAAAATTCATAAAAATAAGGC 4
164 sAD AAAGTCATACAACTACTATGTAAGATATTCGAATTTGTGCTTGTTGGGAAAATAGTAATT 9
表2.b5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
83 20006512 20006543 20074979 20075010 20 20002542 20006543 20074979 20078980
84 25695448 25695479 25711627 25711658 22 25691478 25695479 25711627 25715628
85 152196799 152196830 152218333 152218364 4 152192829 152196830 152214363 152218364
86 39119119 39119150 39150069 39150100 5 39115149 39119150 39146099 39150100
87 168253924 168253955 168295233 168295264 6 168253924 168257925 168291263 168295264
88 134214353 134214384 134250930 134250961 X 134210383 134214384 134246960 134250961
89 156267571 156267602 156333728 156333759 2 156263601 156267602 156333728 156337729
90 213954211 213954242 214032320 214032351 1 213954211 213958212 214028350 214032351
91 30089465 30089496 30144610 30144641 12 30089465 30093466 30144610 30148611
92 25834224 25834255 25940164 25940195 14 25830254 25834255 25936194 25940195
93 82610099 82610130 82624217 82624248 12 82606129 82610130 82624217 82628218
94 106249641 106249672 106284173 106284204 3 106245671 106249672 106280203 106284204
95 115981175 115981206 116082282 116082313 6 115981175 115985176 116082282 116086283
96 22918077 22918108 22970139 22970170 4 22914107 22918108 22970139 22974140
97 76003880 76003911 76083373 76083404 1 75999910 76003911 76083373 76087374
98 33822756 33822787 33864974 33865005 13 33822756 33826757 33864974 33868975
99 4315306 4315337 4363166 4363197 17 4311336 4315337 4363166 4367167
100 39609951 39609982 39623225 39623256 2 39605981 39609982 39623225 39627226
101 46574127 46574158 46633792 46633823 20 46570157 46574158 46629822 46633823
102 25569452 25569483 25695448 25695479 22 25569452 25573453 25691478 25695479
103 25661627 25661658 25695448 25695479 22 25661627 25665628 25691478 25695479
104 39119150 39119181 39150069 39150100 5 39119150 39123151 39146099 39150100
105 13526281 13526312 13559103 13559134 6 13526281 13530282 13559103 13563104
106 154154477 154154508 154217494 154217525 6 154154477 154158478 154217494 154221495
107 229855687 229855718 229872977 229873008 1 229851717 229855718 229869007 229873008
108 112014904 112014935 112124185 112124216 7 112014904 112018905 112124185 112128186
109 46989661 46989692 47069677 47069708 6 46989661 46993662 47065707 47069708
110 177784072 177784103 177834794 177834825 3 177780102 177784103 177830824 177834825
111 29763050 29763081 29809501 29809532 7 29763050 29767051 29809501 29813502
112 229855687 229855718 229911260 229911291 1 229851717 229855718 229907290 229911291
113 195503344 195503375 195566638 195566669 2 195499374 195503375 195562668 195566669
114 30144610 30144641 30181629 30181660 12 30144610 30148611 30181629 30185630
115 95109397 95109428 95167989 95168020 15 95109397 95113398 95164019 95168020
116 14122272 14122303 14160805 14160836 12 14122272 14126273 14156835 14160836
117 66362739 66362770 66470726 66470757 2 66358769 66362770 66466756 66470757
118 46570679 46570710 46643075 46643106 20 46566709 46570710 46643075 46647076
119 64195292 64195323 64225983 64226014 3 64191322 64195323 64225983 64229984
120 105417618 105417649 105460123 105460154 4 105413648 105417649 105456153 105460154
121 162413257 162413288 162474154 162474185 5 162413257 162417258 162470184 162474185
122 82571438 82571469 82630737 82630768 6 82567468 82571469 82630737 82634738
123 58212403 58212434 58252312 58252343 1 58212403 58216404 58248342 58252343
124 132790667 132790698 132849773 132849804 5 132790667 132794668 132845803 132849804
125 11015786 11015817 11118494 11118525 18 11015786 11019787 11118494 11122495
126 75842855 75842886 75864693 75864724 11 75842855 75846856 75860723 75864724
127 39724648 39724679 39792290 39792321 14 39720678 39724679 39792290 39796291
128 110134293 110134324 110153678 110153709 13 110130323 110134324 110153678 110157679
129 209662023 209662054 209702177 209702208 2 209658053 209662054 209698207 209702208
130 29325557 29325588 29376361 29376392 19 29325557 29329558 29376361 29380362
131 69172531 69172562 69218117 69218148 3 69168561 69172562 69218117 69222118
132 107900199 107900230 107960595 107960626 1 107900199 107904200 107960595 107964596
133 8397345 8397376 8424469 8424500 1 8397345 8401346 8420499 8424500
134 49141691 49141722 49212875 49212906 11 49137721 49141722 49212875 49216876
135 89954051 89954082 89987664 89987695 14 89950081 89954082 89983694 89987695
136 24259095 24259126 24324961 24324992 3 24255125 24259126 24320991 24324992
137 88780146 88780177 88890370 88890401 5 88780146 88784147 88886400 88890401
138 137232223 137232254 137343854 137343885 6 137232223 137236224 137339884 137343885
139 106693397 106693428 106729764 106729795 14 106693397 106697398 106725794 106729795
140 148931403 148931434 149013571 149013602 5 148931403 148935404 149013571 149017572
141 45968082 45968113 46028527 46028558 3 45968082 45972083 46024557 46028558
142 52230322 52230353 52319467 52319498 8 52230322 52234323 52319467 52323468
143 89827266 89827297 89863078 89863109 10 89827266 89831267 89863078 89867079
144 198037606 198037637 198099686 198099717 2 198037606 198041607 198099686 198103687
145 102980783 102980814 103034107 103034138 2 102980783 102984784 103034107 103038108
146 157897501 157897532 158003999 158004030 6 157897501 157901502 158000029 158004030
147 30104839 30104870 30143621 30143652 6 30104839 30108840 30143621 30147622
148 46511970 46512001 46568059 46568090 20 46511970 46515971 46564089 46568090
149 86980479 86980510 87043788 87043819 8 86980479 86984480 87043788 87047789
150 89838324 89838355 89905359 89905390 8 89834354 89838355 89905359 89909360
151 42843625 42843656 42890554 42890585 7 42839655 42843656 42886584 42890585
152 102927117 102927148 102983000 102983031 2 102923147 102927148 102983000 102987001
153 168579832 168579863 168632647 168632678 3 168579832 168583833 168628677 168632678
154 6226839 6226870 6298491 6298522 5 6222869 6226870 6298491 6302492
155 12596194 12596225 12619967 12619998 10 12596194 12600195 12615997 12619998
156 90129888 90129919 90157637 90157668 5 90129888 90133889 90153667 90157668
157 155189636 155189667 155219095 155219126 6 155189636 155193637 155219095 155223096
158 11975429 11975460 11994892 11994923 20 11971459 11975460 11994892 11998893
159 229821816 229821847 229859020 229859051 1 229821816 229825817 229859020 229863021
160 66159604 66159635 66218811 66218842 1 66155634 66159635 66218811 66222812
161 110134293 110134324 110146402 110146433 13 110130323 110134324 110146402 110150403
162 69259199 69259230 69320948 69320979 15 69259199 69263200 69320948 69324949
163 23003950 23003981 23065929 23065960 4 22999980 23003981 23065929 23069930
164 28270698 28270729 28333746 28333777 9 28270698 28274699 28329776 28333777
表2.b6
   探針 PCR- 引子 1_ID PCR_ 引子 1
83 ORF15_20_20005082_20006543_20074979_20078974_FR OBD159_1033 GGCACCACACCACAAGCACTGTT
84 ORF15_22_25694410_25695479_25711627_25712666_FR OBD159_1037 ATGTGCTAATCTGGAAGACTCTGTC
85 ORF15_4_152191742_152196830_152216416_152218364_FF OBD159_1041 GGTATCCTGTGAAACTTGCTTCCTTA
86 ORF15_5_39114378_39119150_39147583_39150100_FF OBD159_1045 TTTTGTGTCATCTGTGGTTTGTAT
87 ORF15_6_168253924_168260809_168288516_168295264_RF OBD159_1049 CTCCAACTGTTCTCCTGAGCCGC
88 ORF15_X_134208394_134214384_134247371_134250961_FF OBD159_1053 CTTTTGTGCTCCCAAGAATACTATCA
89 ORF150_2_156262877_156267602_156333728_156335220_FR OBD159_1057 GAAGTCCATTCTTGGGATGAAACAAA
90 ORF151_1_213954211_213958027_214030463_214032351_RF OBD159_1061 ACCAAAGTCTCCTCCAGGGCATCTT
91 ORF151_12_30089465_30094558_30144610_30146709_RR OBD159_1065 AGGCTTCCTTGTTGTGTTCATAAT
92 ORF151_14_25830955_25834255_25934805_25940195_FF OBD159_1069 AGGAAGGAAAGATGTCTACCAAAT
93 ORF152_12_82605920_82610130_82624217_82631901_FR OBD159_1073 CGTGACGAACTGAAGCAGACCCTTTC
94 ORF152_3_106246431_106249672_106270924_106284204_FF OBD159_1077 CACCATCATTTCCCGCCCTTGTC
95 ORF152_6_115981175_115984851_116082282_116083649_RR OBD159_1081 GCTCTGAAAACAACTAACGGTGTA
96 ORF155_4_22917017_22918108_22970139_22978081_FR OBD159_1085 TCTTGAGATGAAATGCCTGTTTGC
97 ORF16_1_76000194_76003911_76083373_76086337_FR OBD159_1089 CTCAGGCAGAAGCAGAACTTGGCTCT
98 ORF16_13_33822756_33828516_33864974_33872117_RR OBD159_1093 TCCAGGTATCTACTTTTCTTCTAT
99 ORF16_17_4314279_4315337_4363166_4364509_FR OBD159_1097 GGGCTAAGATAGGTGAAACGAGGCTG
100 ORF16_2_39607186_39609982_39623225_39627003_FR OBD159_1101 GCTTAGATGTGGCTTTGTCTTTTCTC
101 ORF16_20_46570710_46574158_46631132_46633823_FF OBD159_1105 CCTCCTTTTGCCTCCGATTCCTCATC
102 ORF16_22_25569452_25577394_25694410_25695479_RF OBD159_1109 GTGCTAATCTGGAAGACTCTGTC
103 ORF16_22_25661627_25666380_25694410_25695479_RF OBD159_1113 TGTGCTAATCTGGAAGACTCTGTC
104 ORF16_5_39119150_39126856_39147583_39150100_RF OBD159_1117 CCAGCCTTATGACTTTCAGTGTG
105 ORF16_6_13526281_13531876_13559103_13561354_RR OBD159_1121 GTGCCTCAGTTTTCCTCATCCCTAAG
106 ORF16_6_154154477_154163186_154217494_154220454_RR OBD159_1125 TGGCAGTCATCAAAATCGCTTCTA
107 ORF161_1_229849427_229855718_229869805_229873008_FF OBD159_1129 GCTTTGCTTCACAGGCTTGCCCA
108 ORF161_7_112014904_112016980_112124185_112133295_RR OBD159_1133 TGCCACCCAGTAGGTCTCAGTCT
109 ORF162_6_46989661_46997140_47060758_47069708_RF OBD159_1137 GGTTGCTGGCTGGAGTCTTCTGA
110 ORF163_3_177780034_177784103_177831413_177834825_FF OBD159_1141 ATGTGAGTGTTCCTTGTAGATTAC
111 ORF166_7_29763050_29768509_29809501_29813015_RR OBD159_1145 GAAGAGACCTTATCCTTTTGAACTAC
112 ORF167_1_229849427_229855718_229908605_229911291_FF OBD159_1149 CCACCGATTTATTGCCCTGTAGGACA
113 ORF167_2_195495210_195503375_195555062_195566669_FF OBD159_1153 ACTCTGGCTCCGTTTCTTCCCTGACT
114 ORF168_12_30144610_30146709_30181629_30184999_RR OBD159_1157 CATTCTTCCCTCAGCCATCCATTTGG
115 ORF169_15_95109397_95110442_95161353_95168020_RF OBD159_1161 GCCATAGAGCCTTCCCTGAACAGAGA
116 ORF17_12_14122272_14125684_14156567_14160836_RF OBD159_1165 AATACTCCTCAGAGAACCAATAAT
117 ORF17_2_66361342_66362770_66462513_66470757_FF OBD159_1169 CCCTTCCCTTGGCTTTTGAGTCTGAA
118 ORF17_20_46568090_46570710_46643075_46649811_FR OBD159_1173 TCTACAAGAGAGTGTCCCACCACATA
119 ORF17_3_64194265_64195323_64225983_64228797_FR OBD159_1177 CCAGCCCTCTGTTCTGCTACCAT
120 ORF17_4_105415477_105417649_105457783_105460154_FF OBD159_1181 TGAGAGGTTATGACTTTTCCGAGGTC
121 ORF17_5_162413257_162414861_162467630_162474185_RF OBD159_1185 GGCTAAAATACAAATCCCACAAGAAG
122 ORF17_6_82564978_82571469_82630737_82633712_FR OBD159_1189 GGATTGAAGGTCTCTATTATCAGTCA
123 ORF170_1_58212403_58221374_58250279_58252343_RF OBD159_1193 AGTAATGCCAGCCCCTGAACCCATCT
124 ORF170_5_132790667_132795213_132845490_132849804_RF OBD159_1197 GGCAATGGTCAAGGGCACGAACACAA
125 ORF171_18_11015786_11021011_11118494_11119843_RR OBD159_1201 GAGAATGTCACCAGGATTGCCCAAGC
126 ORF172_11_75842855_75846190_75861382_75864724_RF OBD159_1205 GGCACACAGAAGACGCTCAGCAA
127 ORF173_14_39721868_39724679_39792290_39806170_FR OBD159_1209 GTGTTTCATTTCCTTATCATTTCA
128 ORF174_13_110131405_110134324_110153678_110157618_FR OBD159_1213 ACACAAAGTCAGGAAGGGTGCGTGAA
129 ORF174_2_209659511_209662054_209697743_209702208_FF OBD159_1217 CAGGTATTGCCAGCCACAGCGTTTGA
130 ORF175_19_29325557_29328725_29376361_29378170_RR OBD159_1221 AGATGTGTGTGGGCTCTCGGGCT
131 ORF175_3_69167897_69172562_69218117_69221087_FR OBD159_1225 GTGTCTCGGAGTCTCTTTGAACCAGC
132 ORF18_1_107900199_107901840_107960595_107963096_RR OBD159_1229 GCATAAAGGTAACTTCCTCCTGACG
133 ORF18_1_8397345_8398792_8423193_8424500_RF OBD159_1233 CCAGTAGTGGAGGCTTTGCGTTTT
134 ORF18_11_49136317_49141722_49212875_49219818_FR OBD159_1237 GCTACAGCAGTGTTTAGAGGGAA
135 ORF18_14_89952946_89954082_89986309_89987695_FF OBD159_1241 ACCCAAACAGCATTACAACAGCAGTT
136 ORF18_3_24254159_24259126_24320266_24324992_FF OBD159_1245 TCCTGATGCTTCCTTCGTGCCCC
137 ORF18_5_88780146_88782265_88885645_88890401_RF OBD159_1249 GCCACAAAGTAAAGCAAGAAGTAGGG
138 ORF18_6_137232223_137235679_137341897_137343885_RF OBD159_1253 GGAAATGGTGGCGGGAAGGAGAAATG
139 ORF180_14_106693397_106698909_106725269_106729795_RF OBD159_1257 CCTCCCAGTCATTTCCCTCTCACCAT
140 ORF181_5_148931403_148934917_149013571_149016721_RR OBD159_1261 TACTGCTGAAAACAATCCTATGGG
141 ORF183_3_45968082_45972062_46021458_46028558_RF OBD159_1265 CCCTCCCACTCACCAAACAACAGG
142 ORF183_8_52230322_52233827_52319467_52326208_RR OBD159_1269 ATTCACTTTCACTCTCAGGTGTGTCC
143 ORF186_10_89827266_89829504_89863078_89864649_RR OBD159_1273 CTTGACCTCTTCCTCTGCTGAAT
144 ORF186_2_198037606_198046520_198099686_198102962_RR OBD159_1277 GACTCTTTGTAAGCACAGAACTCAAC
145 ORF187_2_102980783_102983000_103034107_103047709_RR OBD159_1281 AAGGGCAGGAGAGGAATAGGGCAAAG
146 ORF187_6_157897501_157902533_158001619_158004030_RF OBD159_1285 TAAGCCTCCACAAGCCCCATCAT
147 ORF188_6_30104839_30106896_30143621_30146632_RR OBD159_1289 AAAAGTGGGACAAGAAGGAGGCAGC
148 ORF19_20_46511970_46518882_46567001_46568090_RF OBD159_1293 CTACCATAGCCCTTTTATCAATCCAG
149 ORF19_8_86980479_86986149_87043788_87045089_RR OBD159_1297 TGCTTCCTAAAACACGGCAAAGTG
150 ORF19_8_89837286_89838355_89905359_89910373_FR OBD159_1301 AAAGGGTCAAGAAATCAAGATAGC
151 ORF190_7_42842614_42843656_42886026_42890585_FF OBD159_1305 GTGCCTCCTTATCCCCTCAGTCC
152 ORF191_2_102924054_102927148_102983000_102995309_FR OBD159_1309 CTAAGTGTAGAAATAAATGCGAAA
153 ORF191_3_168579832_168593354_168619477_168632678_RF OBD159_1313 GACATTGGCAGAGGTAAATAAATA
154 ORF191_5_6223946_6226870_6298491_6302848_FR OBD159_1317 CTGTTCTCAGCAATGGAATCTCAGGT
155 ORF192_10_12596194_12598368_12616738_12619998_RF OBD159_1321 GTAGCAAACCCACTTCCCTCCTGC
156 ORF193_5_90129888_90142322_90153362_90157668_RF OBD159_1325 GCTGTCTCCCCTGTATTGTTCTGACT
157 ORF193_6_155189636_155191926_155219095_155222285_RR OBD159_1329 CTTGCTTCTGGGTGCCTTTGCTCTTG
158 ORF195_20_11971793_11975460_11994892_11999282_FR OBD159_1333 TTAGGTCCTGGCTGAAGCAGAGGTAT
159 ORF196_1_229821816_229824593_229859020_229862315_RR OBD159_1337 CAGAAGGCAGCCCACCCACTGAT
160 ORF197_1_66151966_66159635_66218811_66223865_FR OBD159_1341 AAACTCCTGACCTCTCACCTGCCTTG
161 ORF197_13_110131405_110134324_110146402_110150942_FR OBD159_1345 AGAATGGGTCTTACTTTGAAAATA
162 ORF197_15_69259199_69263452_69320948_69322275_RR OBD159_1349 ATCATAATGTGGTGTGGCAAGTGC
163 ORF197_4_22994756_23003981_23065929_23067873_FR OBD159_1353 GGAACTACAGTGTCTTCTACAGGGAC
164 ORF198_9_28270698_28275294_28314155_28333777_RF OBD159_1357 GAAAACCAGTCAATCCTCAAGTGTGC
表2.b7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
83 OBD159_1035 CTGGTGAGGAAAGAGAGGGTGGG OBD159_1033_1035 -2.85E-05
84 OBD159_1039 GCGGGTTTGTGTCAGAAGGGTGTAAA OBD159_1037_1039 0.001873877
85 OBD159_1043 TGAAATGAGCAGGTGGGAGTAGGTGG OBD159_1041_1043 0.001322182
86 OBD159_1047 TGTTCCTATTTCTCTCCTATTTTA OBD159_1045_1047 0.002228021
87 OBD159_1051 GCAGCAGGTCCTCAGATGATGTC OBD159_1049_1051 7.56E-05
88 OBD159_1055 CTGTGTGACCTTGGGCAACTTGTGTA OBD159_1053_1055 0.000339187
89 OBD159_1059 GGCTCTAAGATTGAGGCTGTGAT OBD159_1057_1059 0.001793657
90 OBD159_1063 GAGTGGAGATGGTAGAAGAGTCTGTG OBD159_1061_1063 0.002728633
91 OBD159_1067 TTCTTCCCTCAGCCATCCATTTGG OBD159_1065_1067 0.002219464
92 OBD159_1071 AAGTTAGAGTTCAGTTGGAGATGC OBD159_1069_1071 0.000915369
93 OBD159_1075 CATCCTTTATCTTCCCTACCCCATCA OBD159_1073_1075 0.003263876
94 OBD159_1079 CCCACTCCAGTTTGTCCAGGATGC OBD159_1077_1079 0
95 OBD159_1083 ACTTCTACCCTCATCCCTCTCCAT OBD159_1081_1083 0.003860847
96 OBD159_1087 GGTTCAAGGTAGGAAGAGAAAAGC OBD159_1085_1087 0.000870626
97 OBD159_1091 CCACTTTCTCTGATAAGGCAAACGCT OBD159_1089_1091 0.000608575
98 OBD159_1095 TGTTCCTCACTATTCCAAAATGAA OBD159_1093_1095 0.000363009
99 OBD159_1099 CAAAGTAGTAGGGCAAGGCAAATGAA OBD159_1097_1099 0.000679628
100 OBD159_1103 GACCTGGCTACTCTTGAAACACCCAC OBD159_1101_1103 0.001541794
101 OBD159_1107 CCTGAGAGGCAGCAATAACTACTGTT OBD159_1105_1107 0.002451015
102 OBD159_1111 TCTAAGAATCCATTGCGTGTAAAAGC OBD159_1109_1111 0.000974768
103 OBD159_1115 AAGTAACAGAGTAAGAAGAAATAC OBD159_1113_1115 0.001095802
104 OBD159_1119 GTTATGAATGATGTTTGTCCCTCAAC OBD159_1117_1119 0.001101503
105 OBD159_1123 GGGAATGTATGCTGTTCTCAGAG OBD159_1121_1123 0.003371624
106 OBD159_1127 CAGACAAAGCAAAAGATTTCCTAT OBD159_1125_1127 -0.000215853
107 OBD159_1131 GCTCCAGGTCTCTTCCCAAGTGAC OBD159_1129_1131 0.002952499
108 OBD159_1135 GAGACCAGGAACTCAGGACCAGC OBD159_1133_1135 0.001888614
109 OBD159_1139 CCAACCAAATGGGAGGCAACGCC OBD159_1137_1139 0.001218231
110 OBD159_1143 AGGTCTCAAGCAAGGGAGCAACAT OBD159_1141_1143 0.000217315
111 OBD159_1147 GAGTTTCAAGTGCCCTACTGGCTGA OBD159_1145_1147 0.000706585
112 OBD159_1151 TGGAAAACACAGTCCCACCTCTCAGA OBD159_1149_1151 0.001473508
113 OBD159_1155 AATACTGGCAAGAACCCATCTACTGC OBD159_1153_1155 0.001036966
114 OBD159_1159 GCCTTTTATTCTGTGTGTGGCTAAGC OBD159_1157_1159 0.002575321
115 OBD159_1163 CAAGCACTGTCCAATAGGAAGCATAA OBD159_1161_1163 0.00172898
116 OBD159_1167 TCTGCCAACACCACATCATCTTGA OBD159_1165_1167 0.000283452
117 OBD159_1171 GTTCTGGTTTCCACCTGCTTGACTTC OBD159_1169_1171 0.000503528
118 OBD159_1175 ATTGTATCTTTGGTGCCAGCCCCGTG OBD159_1173_1175 0.001624198
119 OBD159_1179 GACTGACTCACCACCCAAGCACG OBD159_1177_1179 0.00084099
120 OBD159_1183 GAAGACATACACAGTAAGCCCTCTGC OBD159_1181_1183 0.001347797
121 OBD159_1187 TACTGGGAAGTTGCCTTAGTCCAAAT OBD159_1185_1187 0.002383468
122 OBD159_1191 CTATTGGGCTTAGAGTGTCTGTCT OBD159_1189_1191 0.000213238
123 OBD159_1195 CCTGAGGATGTGAATGCTGTAGTGAT OBD159_1193_1195 0.001404922
124 OBD159_1199 ACAGTTTCCTTGGAGTTGTGGAGACA OBD159_1197_1199 0.00112924
125 OBD159_1203 CATTCCAGCATTGGTTGGCATTTGAA OBD159_1201_1203 0.002206091
126 OBD159_1207 CCCATTCACCCTCCCTTGCTGGA OBD159_1205_1207 0.000977446
127 OBD159_1211 TCTCCAGTTGTTAGTGTTTCAATA OBD159_1209_1211 0.001131973
128 OBD159_1215 GATTGTATGATTTGCTGGGTTGATTG OBD159_1213_1215 3.25E-05
129 OBD159_1219 GAATGGTGGAAGTTTTCAGGAGCAGA OBD159_1217_1219 0.002014272
130 OBD159_1223 GTCACCGTCCCCAGCAAGAAAGA OBD159_1221_1223 0.00145882
131 OBD159_1227 CCGACTTACGGTGTCCATTATTATGC OBD159_1225_1227 0.001130819
132 OBD159_1231 GTGAGTGTGGGAAAGAGTGGGAAACG OBD159_1229_1231 0.002314207
133 OBD159_1235 GCACAGTTGGGTTATTGCCATTTTGG OBD159_1233_1235 0.00293147
134 OBD159_1239 GATGCTGAATGACCAGTGTGTTC OBD159_1237_1239 0.001575474
135 OBD159_1243 CAGGTGGGAGAGTTTCTTAGTGGGCA OBD159_1241_1243 0.001456432
136 OBD159_1247 GATTCAATGCTGTATCTACTTGCTGA OBD159_1245_1247 0.001218888
137 OBD159_1251 CACCTGGAGTCTGGCTACCGAAATCA OBD159_1249_1251 0.001955857
138 OBD159_1255 TCATCATCGTGGACAAGGAAAGCCTA OBD159_1253_1255 0.000948155
139 OBD159_1259 CCCACACTCCAAAATGAGAAAACCTC OBD159_1257_1259 0.002138327
140 OBD159_1263 CTTCATTGGTCCCTCCATTGACAT OBD159_1261_1263 0.000218068
141 OBD159_1267 GAACCTATTCCCAGTGATGCGGC OBD159_1265_1267 0.002410178
142 OBD159_1271 AGCAACCTCAACCGAGAATCACCCAG OBD159_1269_1271 0.002111818
143 OBD159_1275 CTGCTGGTGGGAATGTAATGAGTAT OBD159_1273_1275 0.000433754
144 OBD159_1279 TAGTTCAAGTTCTTCTCAAAAGCCCC OBD159_1277_1279 0.000676684
145 OBD159_1283 ATAAACTGTGGTGGGCAAATGAGTGT OBD159_1281_1283 0.000373713
146 OBD159_1287 CCTGGGCAACGAGAGCAAAACTC OBD159_1285_1287 0.001679245
147 OBD159_1291 GAGTAAGGTAAAGTCCTCTGTTTCTA OBD159_1289_1291 0.000887765
148 OBD159_1295 CCATTCGCCATTCTTCCTTACCCAGC OBD159_1293_1295 0.001654393
149 OBD159_1299 GAGGAAGTATGACCAGGGCAGGG OBD159_1297_1299 0.001435106
150 OBD159_1303 AGTAAACCTGCCTCCTATTTGATA OBD159_1301_1303 0.001218649
151 OBD159_1307 CCAGGACATTCTCAGCCAAGGAG OBD159_1305_1307 0.002161835
152 OBD159_1311 AGGAACCTAAACTCACTTCTCAGT OBD159_1309_1311 0.001472024
153 OBD159_1315 CAGTCCAAAAGCCAAGAAAGCATA OBD159_1313_1315 0.00228962
154 OBD159_1319 CAATAACTGAATGGCTGAGTCTGAAA OBD159_1317_1319 0.000962844
155 OBD159_1323 CTCTTCTGTTTGTGAGGGCTGCC OBD159_1321_1323 0.00224545
156 OBD159_1327 AACGAGACAGAGTTTGGATGGGTTGC OBD159_1325_1327 0.001327211
157 OBD159_1331 GGTCACTTGAAGCAACCCTTTGGAAA OBD159_1329_1331 0.002826388
158 OBD159_1335 GGATTGGACAGCACCATTTGCCACAA OBD159_1333_1335 0.004203016
159 OBD159_1339 GCCTGCTGCGGGTGACATTTCAA OBD159_1337_1339 0.003039318
160 OBD159_1343 GAGAAGACAGGAACACTGATGCTATC OBD159_1341_1343 0.000199874
161 OBD159_1347 CTTTTATTTTAGATACAGTGGTGT OBD159_1345_1347 -0.000253684
162 OBD159_1351 GAACTCAAAGGCAAATCGGAAATGCT OBD159_1349_1351 0.002820958
163 OBD159_1355 TTCAACTGGTAAGACATTCTGAGGAA OBD159_1353_1355 0.000748968
164 OBD159_1359 CTCAAGTCCTCATCTGTAGAGTCTGG OBD159_1357_1359 0
表2.b8
   基因
83 CFAP61; CRNKL1  A20; RIN2; rs1057519885
84 ADRBK2
85 FBXW7
86 FYB; RICTOR
87 DACT2; rs1473500
88 CCDC160; PHF6
89 NR4A2
90 PROX1
91 rs11050764; rs4931251
92 rs12586774; rs862946
93 METTL25; TMTC2
94 NA
95 FRK; NT5DC1; rs1933737; rs1999930; rs3822857; rs6909746; rs868943; rs9488822
96 NA
97 ST6GALNAC3; rs12095069
98 RFC3
99 ANKFY1; UBE2G1
100 MAP4K3; TMEM178A
101 OCSTAMP; SLC13A3; rs847058
102 ADRBK2; MYO18B
103 ADRBK2
104 FYB; RICTOR; rs1060505056
105 GFOD1; SIRT5
106 CNKSR3; IPCEF1; OPRM1; rs2236256; rs4869818
107 GALNT2; rs4925506
108 DOCK4
109 GPR110; GPR116
110 NA
111 WIPF3; rs850084
112 GALNT2; rs4925506
113 SLC39A10
114 NA
115 NA
116 GRIN2B
117 MEIS1; rs11692361; rs7596219
118 SLC13A3
119 PRICKLE2
120 PPA2; rs1057517679; rs1057517680; rs138215926; rs139076647; rs146013446; rs546693824; rs772083375; rs77928427
121 rs587777363; rs7718928
122 TPBG; rs1369867
123 DAB1; rs527409
124 39692; 39692; GDF9; SHROOM1; SOWAHA
125 PIEZO2
126 UVRAG
127 rs148431766; rs17109786
128 COL4A1; rs11617955; rs641862; rs672601348
129 MAP2
130 UQCRFS1; VSTM2B
131 FRMD4B; LMOD3
132 VAV3; rs2801219; rs345299; rs4915077
133 RERE; rs301806; rs301807
134 FOLH1; TRIM64C
135 EFCAB11; TDP1
136 THRB; rs113700287; rs1158265; rs12485694; rs1505283; rs1505297; rs1505298; rs1505307; rs1868575; rs2167115; rs7610039; rs7610222; rs7622481; rs7640580; rs826230; rs826231; rs826236; rs826238; rs826240; rs862247; rs869784; rs869785; rs9310736; rs9830674
137 MEF2C; rs1085307051; rs114694170; rs11951031; rs11955542; rs11958689; rs12515983; rs12521522; rs17558256; rs17560407; rs17560451; rs3047819; rs3850651; rs3850653; rs397514655; rs397514656; rs4521516; rs545185248; rs61104616; rs62380364; rs700585; rs797045053; rs869312698; rs876661308
138 IFNGR1; rs13201877
139 NA
140 SH3TC2; rs80338933; rs80338934; rs80338935; rs80338936; rs80338937; rs9687065
141 FYCO1; XCR1
142 ST18
143 KIF20B
144 PLCL1
145 NA
146 SNX9; SYNJ2
147 TRIM31; TRIM40
148 OCSTAMP; SLC13A3; ZNF334
149 CNBD1; rs41486944
150 OSGIN2
151 C7orf25
152 TMEM182
153 NA
154 NA
155 CAMK1D
156 NA
157 TFB1M; TIAM2
158 BTBD3; rs16992846
159 GALNT2; rs4925506
160 PDE4B; rs10454453; rs486438; rs490094; rs567279; rs6588190
161 COL4A1; rs641862; rs672601348
162 GLCE; PAQR5
163 rs358231
164 LINGO2; rs10812774; rs7357773
表2.b9
   探針 基因座
1 ORF1_12_10186674_10187896_10218366_10224430_RF GABARAPL1; KLRD1; TMEM52B
2 ORF1_12_10186674_10187896_10218366_10224430_RF GABARAPL1; KLRD1; TMEM52B
3 ORF1_13_31073818_31075538_31104522_31106539_RF HSPH1; TEX26
4 ORF1_13_31073818_31075538_31104522_31106539_RF HSPH1; TEX26
5 ORF1_14_64424976_64426071_64470387_64473618_RF AKAP5; MTHFD1; ZBTB25; rs34181110; rs2236225; rs2281603; rs17824591
6 ORF1_14_64424976_64426071_64470387_64473618_RF AKAP5; MTHFD1; ZBTB25; rs34181110; rs2236225; rs2281603; rs17824591
7 ORF1_2_227779837_227782633_227794345_227796581_FF rs7556897; rs4973341; rs1811711
8 ORF1_2_227779837_227782633_227794345_227796581_FF rs7556897; rs4973341; rs1811711
9 ORF1_20_19898126_19900554_19917735_19921318_RR RIN2; rs181853315
10 ORF1_20_19898126_19900554_19917735_19921318_RR RIN2; rs181853315
11 ORF1_7_41740758_41745973_41778759_41782337_FF INHBA; rs6976118
12 ORF1_7_41740758_41745973_41778759_41782337_FF INHBA; rs6976118
13 ORF1_7_41782337_41783687_41811434_41814240_RR INHBA; rs6976118
14 ORF1_7_41782337_41783687_41811434_41814240_RR INHBA; rs6976118
15 ORF1_8_28471461_28475878_28486639_28490494_FF FBXO16; FZD3
16 ORF1_8_28471461_28475878_28486639_28490494_FF FBXO16; FZD3
17 ORF10_10_14268505_14273692_14331424_14334008_RR FRMD4A; rs1218412; rs12220909
18 ORF10_10_14268505_14273692_14331424_14334008_RR FRMD4A; rs1218412; rs12220909
19 ORF10_11_108858787_108864679_108885482_108890206_RF DDX10; rs10890917
20 ORF10_11_108858787_108864679_108885482_108890206_RF DDX10; rs10890917
21 ORF10_13_51326485_51332663_51385952_51389062_FR FAM124A; INTS6; SERPINE3
22 ORF10_13_51326485_51332663_51385952_51389062_FR FAM124A; INTS6; SERPINE3
23 ORF10_2_39591283_39594585_39623225_39627003_RR MAP4K3; TMEM178A
24 ORF10_2_39591283_39594585_39623225_39627003_RR MAP4K3; TMEM178A
25 ORF10_4_16442257_16447221_16503503_16507970_RR LDB2; rs10939673
26 ORF10_4_16442257_16447221_16503503_16507970_RR LDB2; rs10939673
27 ORF10_6_149361564_149369248_149422330_149424590_FF SUMO4; TAB2; rs267607101; rs267607100; rs1057518422; rs237025; rs2153219
28 ORF10_6_149361564_149369248_149422330_149424590_FF SUMO4; TAB2; rs267607101; rs267607100; rs1057518422; rs237025; rs2153219
29 ORF10_8_10137237_10138418_10231545_10233400_RF MSRA; rs10107815; rs73191547; rs17749155; rs2975735; rs7001567
30 ORF10_8_10137237_10138418_10231545_10233400_RF MSRA; rs10107815; rs73191547; rs17749155; rs2975735; rs7001567
31 ORF10_8_93942397_93946048_93985677_93987921_FR PDP1; rs7006531
32 ORF10_8_93942397_93946048_93985677_93987921_FR PDP1; rs7006531
33 ORF100_13_45859224_45860475_45940546_45944992_RR SIAH3; ZC3H13
34 ORF100_13_45859224_45860475_45940546_45944992_RR SIAH3; ZC3H13
35 ORF102_9_28333777_28339631_28362689_28367003_FF LINGO2; rs7851437
36 ORF102_9_28333777_28339631_28362689_28367003_FF LINGO2; rs7851437
37 ORF102_9_68359355_68363452_68378236_68383399_RF FOXD4L3; PGM5
38 ORF102_9_68359355_68363452_68378236_68383399_RF FOXD4L3; PGM5
39 ORF102_X_115396192_115405592_115455128_115457577_RF LUZP4; PLS3
40 ORF102_X_115396192_115405592_115455128_115457577_RF LUZP4; PLS3
41 ORF103_18_9946347_9948516_9986308_9994472_FR TXNDC2; VAPA; rs29067; rs29066
42 ORF103_18_9946347_9948516_9986308_9994472_FR TXNDC2; VAPA; rs29067; rs29066
43 ORF104_1_213940736_213945091_214000960_214005699_RR PROX1; rs7529073; rs79687284; rs2075423; rs340874; rs340839; rs7541039; rs6665764; rs3767844
44 ORF104_1_213940736_213945091_214000960_214005699_RR PROX1; rs7529073; rs79687284; rs2075423; rs340874; rs340839; rs7541039; rs6665764; rs3767844
45 ORF105_10_10920335_10921487_10936753_10938007_RF rs10752212; rs62209
46 ORF105_10_10920335_10921487_10936753_10938007_RF rs10752212; rs62209
47 ORF105_14_51872356_51878662_51935246_51939339_RF GNG2; rs8015138
48 ORF105_14_51872356_51878662_51935246_51939339_RF GNG2; rs8015138
49 ORF106_18_58215328_58217936_58260024_58262426_FR NEDD4L; rs17064520; rs2288774
50 ORF106_18_58215328_58217936_58260024_58262426_FR NEDD4L; rs17064520; rs2288774
51 ORF106_20_59933715_59935128_59974481_59977463_FR CDH26; FAM217B; PPP1R3D; SYCP2
52 ORF106_20_59933715_59935128_59974481_59977463_FR CDH26; FAM217B; PPP1R3D; SYCP2
53 ORF106_4_84797792_84803613_84849928_84853393_FR CDS1; WDFY3
54 ORF106_4_84797792_84803613_84849928_84853393_FR CDS1; WDFY3
55 ORF107_3_152324462_152326283_152344695_152347512_FR MBNL1; TMEM14E; rs185894411
56 ORF107_3_152324462_152326283_152344695_152347512_FR MBNL1; TMEM14E; rs185894411
57 ORF109_2_104433140_104437833_104474480_104478025_RF rs62152284; rs12615966
58 ORF109_2_104433140_104437833_104474480_104478025_RF rs62152284; rs12615966
59 ORF11_10_121564423_121570750_121595209_121596934_FF FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs755001161
60 ORF11_10_121564423_121570750_121595209_121596934_FF FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs755001161
61 ORF11_10_23011505_23013473_23072347_23075403_FF ARMC3; MSRB2
62 ORF11_10_23011505_23013473_23072347_23075403_FF ARMC3; MSRB2
63 ORF11_2_41846751_41848865_41954493_41957526_FF C2orf91; rs4305317; rs6740960; rs10211025
64 ORF11_2_41846751_41848865_41954493_41957526_FF C2orf91; rs4305317; rs6740960; rs10211025
65 ORF11_5_39079109_39081309_39147583_39150100_RF FYB; RICTOR; rs1060505056
66 ORF11_5_39079109_39081309_39147583_39150100_RF FYB; RICTOR; rs1060505056
67 ORF11_6_134192786_134196745_134322425_134324942_FR SGK1; rs1009840; rs4896030; rs9493873; rs1743966
68 ORF11_6_134192786_134196745_134322425_134324942_FR SGK1; rs1009840; rs4896030; rs9493873; rs1743966
69 ORF11_6_36576177_36578246_36622186_36625149_RF SRSF3; rs7771547
70 ORF11_6_36576177_36578246_36622186_36625149_RF SRSF3; rs7771547
71 ORF11_6_84775145_84786636_84804896_84812997_RR rs77693245; rs72912698
72 ORF11_6_84775145_84786636_84804896_84812997_RR rs77693245; rs72912698
73 ORF11_9_120675206_120677868_120725114_120727254_FR MEGF9; rs7044106
74 ORF11_9_120675206_120677868_120725114_120727254_FR MEGF9; rs7044106
75 ORF110_9_92403506_92407832_92438750_92441269_RF ASPN; CENPP; OGN; OMD
76 ORF110_9_92403506_92407832_92438750_92441269_RF ASPN; CENPP; OGN; OMD
77 ORF111_1_159074759_159077481_159117264_159124296_RR AIM2; rs855871; rs855873; rs855866; rs855867; rs2852720; rs2518564; rs2814764; rs1894043; rs2852727; rs1894044; rs2518569
78 ORF111_1_159074759_159077481_159117264_159124296_RR AIM2; rs855871; rs855873; rs855866; rs855867; rs2852720; rs2518564; rs2814764; rs1894043; rs2852727; rs1894044; rs2518569
79 ORF112_10_112983990_112985695_112999906_113005525_RR TCF7L2; rs17747324; rs34872471; rs7901695; rs4506565; rs7903146; rs4132670
80 ORF112_10_112983990_112985695_112999906_113005525_RR TCF7L2; rs17747324; rs34872471; rs7901695; rs4506565; rs7903146; rs4132670
81 ORF112_2_104411249_104413918_104466236_104469082_FR rs62152284; rs12615966
82 ORF112_2_104411249_104413918_104466236_104469082_FR rs62152284; rs12615966
83 ORF112_22_26756491_26757562_26817002_26819259_FR rs9608521; rs1894720
84 ORF112_22_26756491_26757562_26817002_26819259_FR rs9608521; rs1894720
85 ORF113_21_40396097_40402350_40423687_40428489_RR DSCAM; rs9980603
86 ORF113_21_40396097_40402350_40423687_40428489_RR DSCAM; rs9980603
87 ORF113_5_7540900_7542383_7606244_7610178_FR ADCY2; rs17231202; rs10512928; rs884964; rs12522444; rs11134242; rs4530734; rs12519539; rs34043481
88 ORF113_5_7540900_7542383_7606244_7610178_FR ADCY2; rs17231202; rs10512928; rs884964; rs12522444; rs11134242; rs4530734; rs12519539; rs34043481
89 ORF113_7_28717278_28719857_28769795_28772438_RR CREB5; rs56388170
90 ORF113_7_28717278_28719857_28769795_28772438_RR CREB5; rs56388170
91 ORF115_2_235136683_235138232_235199086_235201324_RF SH3BP4; rs6431360
92 ORF115_2_235136683_235138232_235199086_235201324_RF SH3BP4; rs6431360
93 ORF115_9_131590628_131592768_131654389_131655808_FR RAPGEF1; rs11243444; rs4740283
94 ORF115_9_131590628_131592768_131654389_131655808_FR RAPGEF1; rs11243444; rs4740283
95 ORF117_4_16871472_16876803_16929111_16933508_FF LDB2; rs12503223
96 ORF117_4_16871472_16876803_16929111_16933508_FF LDB2; rs12503223
97 ORF117_6_115981175_115984851_116027406_116036226_FR FRK; rs1933737; rs9488822; rs3822857; rs868943; rs6909746; rs1999930
98 ORF117_6_115981175_115984851_116027406_116036226_FR FRK; rs1933737; rs9488822; rs3822857; rs868943; rs6909746; rs1999930
99 ORF117_X_11308524_11309949_11364232_11365389_RR AMELX; ARHGAP6
100 ORF117_X_11308524_11309949_11364232_11365389_RR AMELX; ARHGAP6
101 ORF118_3_58502739_58504383_58624445_58628835_FR ACOX2; FAM107A; KCTD6; rs150832314; rs1057519329; rs11539086; rs13315591
102 ORF118_3_58502739_58504383_58624445_58628835_FR ACOX2; FAM107A; KCTD6; rs150832314; rs1057519329; rs11539086; rs13315591
103 ORF118_4_84797792_84803613_84853916_84860994_FR CDS1; WDFY3
104 ORF118_4_84797792_84803613_84853916_84860994_FR CDS1; WDFY3
105 ORF119_6_73688989_73690148_73720087_73722647_FR CD109; SLC17A5
106 ORF119_6_73688989_73690148_73720087_73722647_FR CD109; SLC17A5
107 ORF12_10_14331424_14334008_14346291_14350333_RR FRMD4A; rs1218412
108 ORF12_10_14331424_14334008_14346291_14350333_RR FRMD4A; rs1218412
109 ORF12_11_87926403_87934326_87969207_88006264_FR rs16914161
110 ORF12_11_87926403_87934326_87969207_88006264_FR rs16914161
表3.a1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
1 29; 26; 59 2; 2; 2; 1; 2; 2 0.211050406; 0.22548219; 0.19032457; 0.373699919; 0.269881341; 0.261532562
2 29; 26; 59 2; 2; 2; 1; 2; 2 0.211050406; 0.22548219; 0.19032457; 0.373699919; 0.269881341; 0.261532562
3 41; 40 2; 2; 2; 2 0.26460109; 0.271883499; 0.261899069; 0.269983451
4 41; 40 2; 2; 2; 2 0.26460109; 0.271883499; 0.261899069; 0.269983451
5 37; 94; 90; NA 1; 1; 3; 1; 3; 1; NA 0.34481748; 0.331269672; 0.213331923; 0.072103962; 0.219233776; 0.082047788; NA
6 37; 94; 90; NA 1; 1; 3; 1; 3; 1; NA 0.34481748; 0.331269672; 0.213331923; 0.072103962; 0.219233776; 0.082047788; NA
7 NA NA NA
8 NA NA NA
9 175; NA 4; 4; NA 0.096861772; 0.075450093; NA
10 175; NA 4; 4; NA 0.096861772; 0.075450093; NA
11 76; NA 2; 2; NA 0.228521565; 0.209515033; NA
12 76; NA 2; 2; NA 0.228521565; 0.209515033; NA
13 76; NA 2; 2; NA 0.228521565; 0.209515033; NA
14 76; NA 2; 2; NA 0.228521565; 0.209515033; NA
15 63; 57 3; 3; 3; 3 0.216848517; 0.224771745; 0.202795213; 0.214348844
16 63; 57 3; 3; 3; 3 0.216848517; 0.224771745; 0.202795213; 0.214348844
17 107; NA 3; 2; NA 0.188257442; 0.10954189; NA
18 107; NA 3; 2; NA 0.188257442; 0.10954189; NA
19 32; NA 1; 1; NA 0.363856051; 0.35529211; NA
20 32; NA 1; 1; NA 0.363856051; 0.35529211; NA
21 40; 55; 43 2; 2; 1; 1; 2; 2 0.261899069; 0.269983451; 0.250357845; 0.226828239; 0.269116178; 0.27473038
22 40; 55; 43 2; 2; 1; 1; 2; 2 0.261899069; 0.269983451; 0.250357845; 0.226828239; 0.269116178; 0.27473038
23 21; 58 2; 1; 2; 1 0.149991246; 0.37425716; 0.271314317; 0.210195578
24 21; 58 2; 1; 2; 1 0.149991246; 0.37425716; 0.271314317; 0.210195578
25 77; NA 2; 2; NA 0.225457238; 0.206032338; NA
26 77; NA 2; 2; NA 0.225457238; 0.206032338; NA
27 12; 26; NA 1; 1; 1; 2; NA 0.302214299; 0.314913912; 0.375314357; 0.205329626; NA
28 12; 26; NA 1; 1; 1; 2; NA 0.302214299; 0.314913912; 0.375314357; 0.205329626; NA
29 115; NA 4; 4; NA 0.193790369; 0.18374459; NA
30 115; NA 4; 4; NA 0.193790369; 0.18374459; NA
31 38; NA 2; 1; NA 0.255573168; 0.325888812; NA
32 38; NA 2; 1; NA 0.255573168; 0.325888812; NA
33 56; 50 3; 2; 3; 3 0.199907871; 0.267835203; 0.179388457; 0.193973801
34 56; 50 3; 2; 3; 3 0.199907871; 0.267835203; 0.179388457; 0.193973801
35 20; NA 6; 4; NA 7.69e-05; 0.007618647; NA
36 20; NA 6; 4; NA 7.69e-05; 0.007618647; NA
37 17; 17 1; 1; 1; 1 0.350975055; 0.359834557; 0.350975055; 0.359834557
38 17; 17 1; 1; 1; 1 0.350975055; 0.359834557; 0.350975055; 0.359834557
39 17; 29 1; 1; 2; 5 0.350975055; 0.359834557; 0.211050406; 0.005560973
40 17; 29 1; 1; 2; 5 0.350975055; 0.359834557; 0.211050406; 0.005560973
41 51; 111; NA 1; 1; 2; 2; NA 0.272236181; 0.249886334; 0.12134432; 0.099229264; NA
42 51; 111; NA 1; 1; 2; 2; NA 0.272236181; 0.249886334; 0.12134432; 0.099229264; NA
43 53; NA 1; 2; NA 0.261255041; 0.272683217; NA
44 53; NA 1; 2; NA 0.261255041; 0.272683217; NA
45 NA NA NA
46 NA NA NA
47 36; NA 2; 3; NA 0.247980559; 0.12891994; NA
48 36; NA 2; 3; NA 0.247980559; 0.12891994; NA
49 33; NA 4; 2; NA 0.029769861; 0.246924146; NA
50 33; NA 4; 2; NA 0.029769861; 0.246924146; NA
51 17; 17; 4; 94 1; 1; 1; 1; 1; 1; 1; 1 0.350975055; 0.359834557; 0.350975055; 0.359834557; 0.138432982; 0.14804367; 0.09039159; 0.072103962
52 17; 17; 4; 94 1; 1; 1; 1; 1; 1; 1; 1 0.350975055; 0.359834557; 0.350975055; 0.359834557; 0.138432982; 0.14804367; 0.09039159; 0.072103962
53 11; 15 2; 2; 2; 2 0.058427249; 0.066177103; 0.095167761; 0.106401792
54 11; 15 2; 2; 2; 2 0.058427249; 0.066177103; 0.095167761; 0.106401792
55 27; 21; NA 2; 1; 2; 1; NA 0.197546356; 0.37173223; 0.149991246; 0.37425716; NA
56 27; 21; NA 2; 1; 2; 1; NA 0.197546356; 0.37173223; 0.149991246; 0.37425716; NA
57 NA NA NA
58 NA NA NA
59 190; NA 5; 4; NA 0.112399625; 0.054978865; NA
60 190; NA 5; 4; NA 0.112399625; 0.054978865; NA
61 95; 92 1; 1; 1; 1 0.087779635; 0.069791754; 0.095817628; 0.076933881
62 95; 92 1; 1; 1; 1 0.087779635; 0.069791754; 0.095817628; 0.076933881
63 58; NA 1; 1; NA 0.234279681; 0.210195578; NA
64 58; NA 1; 1; NA 0.234279681; 0.210195578; NA
65 10; 8; NA 2; 2; 2; 2; NA 0.049739473; 0.05651991; 0.033505489; 0.038320555; NA
66 10; 8; NA 2; 2; 2; 2; NA 0.049739473; 0.05651991; 0.033505489; 0.038320555; NA
67 108; NA 4; 1; NA 0.198465555; 0.045253641; NA
68 108; NA 4; 1; NA 0.198465555; 0.045253641; NA
69 27; NA 1; 1; NA 0.374553651; 0.37173223; NA
70 27; NA 1; 1; NA 0.374553651; 0.37173223; NA
71 NA NA NA
72 NA NA NA
73 25; NA 1; 1; NA 0.375519541; 0.375121431; NA
74 25; NA 1; 1; NA 0.375519541; 0.375121431; NA
75 7; 90; 9; 8 1; 1; 1; 1; 1; 1; 1; 1 0.215038813; 0.227740664; 0.101520575; 0.082047788; 0.255358235; 0.268692312; 0.236185646; 0.249326315
76 7; 90; 9; 8 1; 1; 1; 1; 1; 1; 1; 1 0.215038813; 0.227740664; 0.101520575; 0.082047788; 0.255358235; 0.268692312; 0.236185646; 0.249326315
77 58; NA 1; 1; NA 0.234279681; 0.210195578; NA
78 58; NA 1; 1; NA 0.234279681; 0.210195578; NA
79 28; NA 1; 1; NA 0.373281001; 0.369266824; NA
80 28; NA 1; 1; NA 0.373281001; 0.369266824; NA
81 NA NA NA
82 NA NA NA
83 NA NA NA
84 NA NA NA
85 42; NA 1; 1; NA 0.320791853; 0.303213711; NA
86 42; NA 1; 1; NA 0.320791853; 0.303213711; NA
87 90; NA 3; 3; NA 0.219233776; 0.208104371; NA
88 90; NA 3; 3; NA 0.219233776; 0.208104371; NA
89 54; NA 3; 3; NA 0.193670022; 0.206710786; NA
90 54; NA 3; 3; NA 0.193670022; 0.206710786; NA
91 79; NA 1; 1; NA 0.138189127; 0.115771126; NA
92 79; NA 1; 1; NA 0.138189127; 0.115771126; NA
93 65; NA 2; 2; NA 0.258408092; 0.245566966; NA
94 65; NA 2; 2; NA 0.258408092; 0.245566966; NA
95 77; NA 2; 2; NA 0.225457238; 0.206032338; NA
96 77; NA 2; 2; NA 0.225457238; 0.206032338; NA
97 28; NA 3; 2; NA 0.071800115; 0.219149094; NA
98 28; NA 3; 2; NA 0.071800115; 0.219149094; NA
99 33; 35 1; 3; 1; 3 0.360592644; 0.112054294; 0.353195365; 0.123360639
100 33; 35 1; 3; 1; 3 0.360592644; 0.112054294; 0.353195365; 0.123360639
101 25; 53; 12; NA 1; 1; 1; 1; 1; 1; NA 0.375519541; 0.375121431; 0.261255041; 0.238249082; 0.302214299; 0.314913912; NA
102 25; 53; 12; NA 1; 1; 1; 1; 1; 1; NA 0.375519541; 0.375121431; 0.261255041; 0.238249082; 0.302214299; 0.314913912; NA
103 11; 15 2; 2; 2; 2 0.058427249; 0.066177103; 0.095167761; 0.106401792
104 11; 15 2; 2; 2; 2 0.058427249; 0.066177103; 0.095167761; 0.106401792
105 34; 34 3; 3; 3; 3 0.103367502; 0.117734198; 0.103367502; 0.117734198
106 34; 34 3; 3; 3; 3 0.103367502; 0.117734198; 0.103367502; 0.117734198
107 107; NA 3; 2; NA 0.188257442; 0.10954189; NA
108 107; NA 3; 2; NA 0.188257442; 0.10954189; NA
109 NA NA NA
110 NA NA NA
表3.a2
   FDR_HyperG Percent_Sig logFC AveExpr
1 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.9; 6.9; 7.69; 3.85; 3.39; 3.39 -0.811293893 -0.811293893
2 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.9; 6.9; 7.69; 3.85; 3.39; 3.39 -0.730775029 -0.730775029
3 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.88; 4.88; 5; 5 -0.870692099 -0.870692099
4 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.88; 4.88; 5; 5 -0.746276793 -0.746276793
5 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.7; 2.7; 3.19; 1.06; 3.33; 1.11; NA -0.754595643 -0.754595643
6 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.7; 2.7; 3.19; 1.06; 3.33; 1.11; NA -0.62865404 -0.62865404
7 NA NA -0.705258334 -0.705258334
8 NA NA -0.662539712 -0.662539712
9 0.375519541; 0.376115439; NA 2.29; 2.29; NA -1.046596585 -1.046596585
10 0.375519541; 0.376115439; NA 2.29; 2.29; NA -0.895641708 -0.895641708
11 0.375519541; 0.376115439; NA 2.63; 2.63; NA -1.458942479 -1.458942479
12 0.375519541; 0.376115439; NA 2.63; 2.63; NA -1.370124623 -1.370124623
13 0.375519541; 0.376115439; NA 2.63; 2.63; NA -1.492717199 -1.492717199
14 0.375519541; 0.376115439; NA 2.63; 2.63; NA -1.373707801 -1.373707801
15 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 4.76; 5.26; 5.26 -0.957766564 -0.957766564
16 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 4.76; 5.26; 5.26 -0.827448174 -0.827448174
17 0.375519541; 0.376115439; NA 2.8; 1.87; NA -0.987154267 -0.987154267
18 0.375519541; 0.376115439; NA 2.8; 1.87; NA -0.888828194 -0.888828194
19 0.375519541; 0.376115439; NA 3.12; 3.12; NA -0.770134963 -0.770134963
20 0.375519541; 0.376115439; NA 3.12; 3.12; NA -0.753701128 -0.753701128
21 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 5; 5; 1.82; 1.82; 4.65; 4.65 -0.837223688 -0.837223688
22 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 5; 5; 1.82; 1.82; 4.65; 4.65 -0.76043036 -0.76043036
23 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.52; 4.76; 3.45; 1.72 -1.078732682 -1.078732682
24 0.375519541; 0.376115439; 0.375519541; 0.376115439 9.52; 4.76; 3.45; 1.72 -0.731193465 -0.731193465
25 0.375519541; 0.376115439; NA 2.6; 2.6; NA -1.014117733 -1.014117733
26 0.375519541; 0.376115439; NA 2.6; 2.6; NA -0.814900115 -0.814900115
27 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 8.33; 8.33; 3.85; 7.69; NA -0.993693839 -0.993693839
28 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 8.33; 8.33; 3.85; 7.69; NA -0.707731847 -0.707731847
29 0.375519541; 0.376115439; NA 3.48; 3.48; NA -0.775068462 -0.775068462
30 0.375519541; 0.376115439; NA 3.48; 3.48; NA -0.714999895 -0.714999895
31 0.375519541; 0.376115439; NA 5.26; 2.63; NA -0.889082025 -0.889082025
32 0.375519541; 0.376115439; NA 5.26; 2.63; NA -0.738623593 -0.738623593
33 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.36; 3.57; 6; 6 -0.847546213 -0.847546213
34 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.36; 3.57; 6; 6 -0.726803577 -0.726803577
35 0.008046243; 0.242844385; NA 30; 20; NA -1.041642042 -1.041642042
36 0.008046243; 0.242844385; NA 30; 20; NA -0.76731615 -0.76731615
37 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 5.88; 5.88; 5.88 -1.450078375 -1.450078375
38 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 5.88; 5.88; 5.88 -1.426719737 -1.426719737
39 0.375519541; 0.376115439; 0.375519541; 0.217379602 5.88; 5.88; 6.9; 17.24 -1.169451852 -1.169451852
40 0.375519541; 0.376115439; 0.375519541; 0.217379602 5.88; 5.88; 6.9; 17.24 -0.841132198 -0.841132198
41 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.96; 1.96; 1.8; 1.8; NA -0.862556659 -0.862556659
42 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.96; 1.96; 1.8; 1.8; NA -0.825391888 -0.825391888
43 0.375519541; 0.376115439; NA 1.89; 3.77; NA -1.461109862 -1.461109862
44 0.375519541; 0.376115439; NA 1.89; 3.77; NA -1.08826989 -1.08826989
45 NA NA -1.24308947 -1.24308947
46 NA NA -0.97543175 -0.97543175
47 0.375519541; 0.376115439; NA 5.56; 8.33; NA -1.555194951 -1.555194951
48 0.375519541; 0.376115439; NA 5.56; 8.33; NA -1.27119543 -1.27119543
49 0.375519541; 0.376115439; NA 12.12; 6.06; NA -0.812425289 -0.812425289
50 0.375519541; 0.376115439; NA 12.12; 6.06; NA -0.807901825 -0.807901825
51 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 5.88; 5.88; 5.88; 25; 25; 1.06; 1.06 -0.817258193 -0.817258193
52 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 5.88; 5.88; 5.88; 25; 25; 1.06; 1.06 -0.769055649 -0.769055649
53 0.375519541; 0.376115439; 0.375519541; 0.376115439 18.18; 18.18; 13.33; 13.33 -0.838270747 -0.838270747
54 0.375519541; 0.376115439; 0.375519541; 0.376115439 18.18; 18.18; 13.33; 13.33 -0.82008196 -0.82008196
55 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 7.41; 3.7; 9.52; 4.76; NA -0.904903591 -0.904903591
56 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 7.41; 3.7; 9.52; 4.76; NA -0.718536059 -0.718536059
57 NA NA -1.272407601 -1.272407601
58 NA NA -1.194672477 -1.194672477
59 0.375519541; 0.376115439; NA 2.63; 2.11; NA -1.438572631 -1.438572631
60 0.375519541; 0.376115439; NA 2.63; 2.11; NA -1.083399373 -1.083399373
61 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.05; 1.05; 1.09; 1.09 -1.032550544 -1.032550544
62 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.05; 1.05; 1.09; 1.09 -0.8091867 -0.8091867
63 0.375519541; 0.376115439; NA 1.72; 1.72; NA -1.064941315 -1.064941315
64 0.375519541; 0.376115439; NA 1.72; 1.72; NA -0.800833097 -0.800833097
65 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 20; 20; 25; 25; NA -0.725518377 -0.725518377
66 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 20; 20; 25; 25; NA -0.628005315 -0.628005315
67 0.375519541; 0.376115439; NA 3.7; 0.93; NA -0.926664266 -0.926664266
68 0.375519541; 0.376115439; NA 3.7; 0.93; NA -0.875479555 -0.875479555
69 0.375519541; 0.376115439; NA 3.7; 3.7; NA -0.954471796 -0.954471796
70 0.375519541; 0.376115439; NA 3.7; 3.7; NA -0.77984372 -0.77984372
71 NA NA -1.079623185 -1.079623185
72 NA NA -1.007542197 -1.007542197
73 0.375519541; 0.376115439; NA 4; 4; NA -0.911873067 -0.911873067
74 0.375519541; 0.376115439; NA 4; 4; NA -0.833855338 -0.833855338
75 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 14.29; 14.29; 1.11; 1.11; 11.11; 11.11; 12.5; 12.5 -0.961192926 -0.961192926
76 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 14.29; 14.29; 1.11; 1.11; 11.11; 11.11; 12.5; 12.5 -0.948571977 -0.948571977
77 0.375519541; 0.376115439; NA 1.72; 1.72; NA -0.920418356 -0.920418356
78 0.375519541; 0.376115439; NA 1.72; 1.72; NA -0.81847409 -0.81847409
79 0.375519541; 0.376115439; NA 3.57; 3.57; NA -0.905179933 -0.905179933
80 0.375519541; 0.376115439; NA 3.57; 3.57; NA -0.779248109 -0.779248109
81 NA NA -1.338505835 -1.338505835
82 NA NA -1.207676352 -1.207676352
83 NA NA -0.921755928 -0.921755928
84 NA NA -0.775338524 -0.775338524
85 0.375519541; 0.376115439; NA 2.38; 2.38; NA -0.746343924 -0.746343924
86 0.375519541; 0.376115439; NA 2.38; 2.38; NA -0.746041732 -0.746041732
87 0.375519541; 0.376115439; NA 3.33; 3.33; NA -1.055710742 -1.055710742
88 0.375519541; 0.376115439; NA 3.33; 3.33; NA -1.011241915 -1.011241915
89 0.375519541; 0.376115439; NA 5.56; 5.56; NA -0.874274528 -0.874274528
90 0.375519541; 0.376115439; NA 5.56; 5.56; NA -0.855516236 -0.855516236
91 0.375519541; 0.376115439; NA 1.27; 1.27; NA -1.104484252 -1.104484252
92 0.375519541; 0.376115439; NA 1.27; 1.27; NA -1.102912394 -1.102912394
93 0.375519541; 0.376115439; NA 3.08; 3.08; NA -0.824921993 -0.824921993
94 0.375519541; 0.376115439; NA 3.08; 3.08; NA -0.709988075 -0.709988075
95 0.375519541; 0.376115439; NA 2.6; 2.6; NA -0.797761745 -0.797761745
96 0.375519541; 0.376115439; NA 2.6; 2.6; NA -0.737588966 -0.737588966
97 0.375519541; 0.376115439; NA 10.71; 7.14; NA -0.78873619 -0.78873619
98 0.375519541; 0.376115439; NA 10.71; 7.14; NA -0.68221474 -0.68221474
99 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.03; 9.09; 2.86; 8.57 -0.846146488 -0.846146488
100 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.03; 9.09; 2.86; 8.57 -0.837515806 -0.837515806
101 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4; 4; 1.89; 1.89; 8.33; 8.33; NA -1.027739319 -1.027739319
102 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4; 4; 1.89; 1.89; 8.33; 8.33; NA -0.975106847 -0.975106847
103 0.375519541; 0.376115439; 0.375519541; 0.376115439 18.18; 18.18; 13.33; 13.33 -0.975818539 -0.975818539
104 0.375519541; 0.376115439; 0.375519541; 0.376115439 18.18; 18.18; 13.33; 13.33 -0.849468101 -0.849468101
105 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.82; 8.82; 8.82; 8.82 -1.048873263 -1.048873263
106 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.82; 8.82; 8.82; 8.82 -0.849272244 -0.849272244
107 0.375519541; 0.376115439; NA 2.8; 1.87; NA -0.782559404 -0.782559404
108 0.375519541; 0.376115439; NA 2.8; 1.87; NA -0.773997879 -0.773997879
109 NA NA -0.864606137 -0.864606137
110 NA NA -0.664595001 -0.664595001
表3.a3
   t P值 adj.P.Val B FC FC_1 LS
1 -7.26006068 0.0000101 0.000175139 3.627400598 0.569870536 -1.75478453 -1
2 -5.243995352 0.000210073 0.002457842 0.58020377 0.602580115 -1.659530367 -1
3 -8.646560156 0.00000175 0.00010547 5.488389749 0.546884433 -1.828539889 -1
4 -9.848792715 0.000000428 0.0000236 6.872121102 0.596140051 -1.677458172 -1
5 -10.17408165 0.000000301 0.000019 7.228469882 0.592712487 -1.687158651 -1
6 -7.671264242 0.00000595 0.000226232 4.239067799 0.646779546 -1.546121868 -1
7 -5.452024524 0.000147984 0.001093879 0.852395818 0.613332653 -1.630436591 -1
8 -3.804767457 0.002531086 0.01396214 -1.959895955 0.631765162 -1.582866642 -1
9 -8.278137882 0.00000274 0.00014005 5.030018062 0.484108864 -2.065651084 -1
10 -7.1983049 0.000011 0.000185081 3.540053384 0.53750806 -1.86043722 -1
11 -12.58608003 0.0000000288 0.00000502 9.582975903 0.363759674 -2.749067782 -1
12 -9.54041302 0.00000062 0.0000553 6.536791786 0.386857829 -2.584928943 -1
13 -11.1400876 0.000000112 0.0000104 8.22914885 0.355342659 -2.814185053 -1
14 -10.11233895 0.000000332 0.000038 7.1636613 0.385898194 -2.591357033 -1
15 -13.08345851 0.0000000195 0.00000783 9.958390188 0.514853341 -1.942300691 -1
16 -7.315134124 0.00000936 0.000166812 3.704870236 0.56352512 -1.774543788 -1
17 -6.392679521 0.0000353 0.000723203 2.414672405 0.504471871 -1.982271079 -1
18 -7.335610294 0.00000911 0.000163566 3.733571229 0.540052589 -1.851671522 -1
19 -6.38175463 0.0000358 0.0007311 2.398110579 0.586362618 -1.705429318 -1
20 -5.221072971 0.000215417 0.001432348 0.464971511 0.593080101 -1.686112886 -1
21 -11.90379465 0.0000000558 0.0000134 8.932846123 0.559719654 -1.786608695 -1
22 -12.32092761 0.0000000366 0.00000567 9.346570284 0.59032021 -1.693995873 -1
23 -8.665673296 0.00000166 0.0000551 5.484804121 0.473444532 -2.112179847 -1
24 -5.202088287 0.000224994 0.002570215 0.509761053 0.60240537 -1.660011763 -1
25 -9.924213715 0.000000394 0.0000223 6.955657597 0.495131029 -2.019667406 -1
26 -7.794043768 0.00000507 0.00020589 4.402809452 0.568447842 -1.759176351 -1
27 -7.864436798 0.00000452 0.000103636 4.456020198 0.502190332 -1.991276884 -1
28 -6.522106102 0.0000292 0.000639378 2.609593742 0.61228199 -1.633234386 -1
29 -11.12098192 0.000000118 0.0000205 8.193707101 0.584360893 -1.711271256 -1
30 -6.581592337 0.0000263 0.000329703 2.639504808 0.609205176 -1.641483098 -1
31 -5.12615141 0.000251908 0.001609552 0.303637682 0.539957579 -1.851997338 -1
32 -3.91780668 0.002063293 0.012051049 -1.753111971 0.599310854 -1.668583164 -1
33 -9.03942288 0.0000011 0.0000782 5.959952938 0.555729136 -1.799437773 -1
34 -6.399309184 0.0000343 0.000393125 2.363285494 0.604241183 -1.654968293 -1
35 -5.912028873 0.0000716 0.000656333 1.601923755 0.485774262 -2.058569336 -1
36 -5.116568358 0.000259009 0.002829599 0.365266577 0.587509404 -1.702100414 -1
37 -13.66980287 0.0000000114 0.000003 10.49913688 0.36600154 -2.732228938 -1
38 -13.52342727 0.0000000134 0.00000639 10.31615292 0.371975695 -2.688347689 -1
39 -7.660963112 0.0000059 0.0001232 4.182282504 0.444590229 -2.249262206 -1
40 -5.971829876 0.0000664 0.001107418 1.764387775 0.558205329 -1.791455489 -1
41 -6.902093975 0.0000169 0.000446018 3.168293858 0.549977057 -1.818257666 -1
42 -6.494775221 0.0000298 0.000357672 2.508527608 0.56432889 -1.772016316 -1
43 -10.471397 0.00000022 0.0000159 7.545396321 0.363213603 -2.753200852 -1
44 -9.681451147 0.00000053 0.0000505 6.694430782 0.47032506 -2.126189065 -1
45 -7.176643041 0.0000113 0.000188484 3.509294753 0.422466992 -2.367048834 -1
46 -8.486463585 0.00000212 0.000119044 5.291167668 0.50858762 -1.966229536 -1
47 -9.024631716 0.00000109 0.0000421 5.921562838 0.340282544 -2.93873435 -1
48 -10.67589027 0.000000185 0.0000271 7.750500728 0.414316324 -2.41361477 -1
49 -7.697123323 0.00000575 0.000221811 4.273714214 0.569423805 -1.756161213 -1
50 -7.314755086 0.00000937 0.000166881 3.704338427 0.571211993 -1.750663524 -1
51 -11.84812377 0.0000000588 0.0000136 8.881901597 0.567519476 -1.762054067 -1
52 -10.5322844 0.000000207 0.0000153 7.609294574 0.586801454 -1.704153923 -1
53 -6.385515137 0.000035 0.000398491 2.342193529 0.559313576 -1.787905825 -1
54 -8.801749601 0.00000145 0.0000936 5.676747126 0.566409764 -1.765506288 -1
55 -7.533982769 0.00000698 0.000137048 4.008786409 0.534068392 -1.872419365 -1
56 -6.874524851 0.0000176 0.000458246 3.128433471 0.607713793 -1.645511443 -1
57 -9.603785157 0.00000056 0.0000279 6.596851595 0.413968357 -2.415643572 -1
58 -9.343873803 0.000000773 0.0000634 6.313680591 0.436885619 -2.288928626 -1
59 -9.278626339 0.000000809 0.0000351 6.222075719 0.368932137 -2.710525596 -1
60 -6.706262889 0.0000223 0.00053607 2.882875297 0.471915554 -2.119023185 -1
61 -9.998542088 0.000000363 0.0000212 7.037440135 0.488845154 -2.045637545 -1
62 -7.206054424 0.0000111 0.00033767 3.600886139 0.570703494 -1.752223371 -1
63 -12.89727391 0.0000000219 0.00000432 9.854104892 0.477992102 -2.092084777 -1
64 -6.778124827 0.0000202 0.000502215 2.988229744 0.57401761 -1.742106831 -1
65 -6.824231864 0.0000185 0.000262098 3.000017863 0.604779701 -1.65349465 -1
66 -9.589736122 0.000000587 0.0000537 6.592152528 0.647070444 -1.545426792 -1
67 -6.031878393 0.0000605 0.001040599 1.858720478 0.5260733 -1.900875792 -1
68 -7.013784432 0.0000142 0.000219353 3.276032354 0.545072653 -1.834617816 -1
69 -8.75382475 0.00000149 0.0000516 5.593397511 0.516030486 -1.937870005 -1
70 -6.08651819 0.0000557 0.000982738 1.944108069 0.582429882 -1.716944874 -1
71 -7.928733975 0.00000426 0.000184468 4.58023745 0.473152389 -2.113483992 -1
72 -9.46216961 0.000000657 0.0000307 6.434973271 0.497392894 -2.010483083 -1
73 -9.779482829 0.000000461 0.0000247 6.794858778 0.531494598 -1.881486668 -1
74 -6.917077518 0.0000166 0.000439662 3.189913698 0.561027993 -1.782442254 -1
75 -5.464709038 0.000144995 0.001078085 0.873461456 0.513632029 -1.946919084 -1
76 -7.262009319 0.0000103 0.00032165 3.679158958 0.518145084 -1.929961378 -1
77 -6.355337644 0.0000366 0.000410618 2.295957012 0.528355784 -1.892664052 -1
78 -10.36225489 0.000000255 0.0000327 7.427556628 0.567041374 -1.763539745 -1
79 -9.772002141 0.000000465 0.0000248 6.786491279 0.533966103 -1.872778054 -1
80 -8.067889513 0.00000357 0.000164943 4.761166073 0.582670385 -1.716236187 -1
81 -9.127661293 0.000000962 0.0000392 6.04429851 0.395429981 -2.528892718 -1
82 -8.991904628 0.00000116 0.0000815 5.903833758 0.432965402 -2.309653373 -1
83 -6.410265384 0.0000338 0.000389213 2.380019174 0.527866155 -1.89441962 -1
84 -5.020736206 0.000303639 0.00316874 0.202179767 0.584251515 -1.711591624 -1
85 -5.812981356 0.0000835 0.000728651 1.443055458 0.596112312 -1.677536228 -1
86 -7.190171156 0.0000113 0.000342404 3.578591234 0.596237189 -1.677184884 -1
87 -11.25389492 0.000000104 0.0000189 8.322746423 0.481060169 -2.078742044 -1
88 -7.726475713 0.00000541 0.000116503 4.270988664 0.49611899 -2.015645482 -1
89 -6.55717777 0.0000272 0.000336554 2.602777858 0.545528121 -1.833086071 -1
90 -6.597569244 0.0000261 0.000593503 2.72215348 0.552667531 -1.809406095 -1
91 -7.313278127 0.00000939 0.00016713 3.702265997 0.465068699 -2.150219963 -1
92 -12.42238865 0.0000000348 0.0000104 9.396097401 0.46557568 -2.147878512 -1
93 -5.756993857 0.0000912 0.000775378 1.352639923 0.564512725 -1.771439253 -1
94 -5.235445229 0.00021303 0.002481219 0.565851161 0.611325192 -1.635790596 -1
95 -5.877218781 0.0000756 0.000680268 1.546247993 0.575240937 -1.738402007 -1
96 -5.915679735 0.0000723 0.001172545 1.675712313 0.599740803 -1.667386969 -1
97 -8.347567157 0.00000245 0.00007 5.085501187 0.578850947 -1.727560445 -1
98 -8.010937379 0.00000384 0.000173085 4.687407788 0.623207828 -1.604601154 -1
99 -6.857265046 0.0000177 0.000254107 3.048471278 0.556268575 -1.797692778 -1
100 -9.479761353 0.000000663 0.0000575 6.468370711 0.559606333 -1.786970485 -1
101 -10.95352241 0.000000135 0.0000117 8.042297446 0.490478119 -2.038826936 -1
102 -12.3434877 0.0000000373 0.0000109 9.326908953 0.50870217 -1.965786779 -1
103 -6.695483301 0.0000223 0.000295828 2.809737071 0.508451285 -1.966756755 -1
104 -6.839385861 0.0000185 0.000473389 3.077476369 0.554989314 -1.801836493 -1
105 -7.188458418 0.0000111 0.00018664 3.526079682 0.483345507 -2.068913406 -1
106 -6.784662393 0.00002 0.000499287 2.99777863 0.555064663 -1.801591897 -1
107 -8.9573592 0.00000117 0.0000441 5.840799072 0.581334565 -1.720179842 -1
108 -6.46577558 0.0000317 0.000675248 2.525048906 0.584794692 -1.710001842 -1
109 -11.43498382 0.0000000839 0.00000888 8.518555684 0.54919632 -1.8208425 -1
110 -8.943192738 0.00000123 0.0000843 5.846045718 0.630865779 -1.585123229 -1
表3.a4
      探針序列 探針位置
偵測到之環 60 mer Chr
1 sAD TCCTTGGATAGGACATTACATATCATTTTCGAGTAATATTAAAGATTCCAGGACTCACAA 12
2 mAD TCCTTGGATAGGACATTACATATCATTTTCGAGTAATATTAAAGATTCCAGGACTCACAA 12
3 mAD AAAGAAATTCTTAGCTCTAGATTTATCATCGAATCATGAAAAGTGAAAGTCTGAGCTTTG 13
4 sAD AAAGAAATTCTTAGCTCTAGATTTATCATCGAATCATGAAAAGTGAAAGTCTGAGCTTTG 13
5 sAD CCTTATTTTTTATAGTTAAGAATGTTTTTCGAGTTTTGGCTGCTTTTCTCCCCAAGTAGA 14
6 mAD CCTTATTTTTTATAGTTAAGAATGTTTTTCGAGTTTTGGCTGCTTTTCTCCCCAAGTAGA 14
7 sAD GCATTGTTTCTTCATTTTATTTTATTTTTCGAAGAACTGGAAGAAGAGAACCAATGGAAA 2
8 mAD GCATTGTTTCTTCATTTTATTTTATTTTTCGAAGAACTGGAAGAAGAGAACCAATGGAAA 2
9 mAD TTTTGAAAATATGAAAAGGAATTTCTGTTCGATATATACTGTACATCTCAAGAAATATGT 20
10 sAD TTTTGAAAATATGAAAAGGAATTTCTGTTCGATATATACTGTACATCTCAAGAAATATGT 20
11 sAD CTCAATCAAGGATACTTATTATTACTTCTCGAAGCCTTAAAGCTTGGAGCATTCCTGCTA 7
12 mAD CTCAATCAAGGATACTTATTATTACTTCTCGAAGCCTTAAAGCTTGGAGCATTCCTGCTA 7
13 sAD TTCAATTTTGGTCAATTTATTTCAACCATCGAAAGGTAGGATCTGAGATCCCACCCTAAA 7
14 mAD TTCAATTTTGGTCAATTTATTTCAACCATCGAAAGGTAGGATCTGAGATCCCACCCTAAA 7
15 mAD CTAAAATGAATCCTAAAGGTCTTTTTGTTCGACGCGTCTTCATTCTAGGGTTATATTGAG 8
16 sAD CTAAAATGAATCCTAAAGGTCTTTTTGTTCGACGCGTCTTCATTCTAGGGTTATATTGAG 8
17 mAD TATGAAGATGAATGAAAAAATAAATAAATCGAAATAAGAAACTAGGGGGAAGAAATTAAT 10
18 sAD TATGAAGATGAATGAAAAAATAAATAAATCGAAATAAGAAACTAGGGGGAAGAAATTAAT 10
19 mAD TTCATAGAAATGTCTTAGATAATCATTATCGAGCTCCTCAAGTTGCATATGGAAAACTTG 11
20 sAD TTCATAGAAATGTCTTAGATAATCATTATCGAGCTCCTCAAGTTGCATATGGAAAACTTG 11
21 mAD TTGAAACTTTACAGGAGGTGATTAAGAATCGACTGCTCTTTGAACTCCACTGTTTAAAAG 13
22 sAD TTGAAACTTTACAGGAGGTGATTAAGAATCGACTGCTCTTTGAACTCCACTGTTTAAAAG 13
23 sAD CATATCTGTGAATATTTTTTTAAAACCATCGATTCAGCTGGGGAAAAATGAAAATAACAA 2
24 mAD CATATCTGTGAATATTTTTTTAAAACCATCGATTCAGCTGGGGAAAAATGAAAATAACAA 2
25 sAD TCAAATTTCCATATTTTACTTTATCACCTCGATAAAAACAATGTTCACACTGATTTGACA 4
26 mAD TCAAATTTCCATATTTTACTTTATCACCTCGATAAAAACAATGTTCACACTGATTTGACA 4
27 sAD ATAAAAATAAGGTGGGTAGTTTTCAACTTCGAAAAAGAAAAGAAAAGAAAAGAAAACCAA 6
28 mAD ATAAAAATAAGGTGGGTAGTTTTCAACTTCGAAAAAGAAAAGAAAAGAAAAGAAAACCAA 6
29 mAD AATATGAAGAAATGAAATATAAATTGACTCGACTTAAAAGCATATTTTAAAAAATTGGTT 8
30 sAD AATATGAAGAAATGAAATATAAATTGACTCGACTTAAAAGCATATTTTAAAAAATTGGTT 8
31 sAD ATGGTAAATGACTTGTATTTATTAGATATCGAATAGTCTCTGTGGTGATTTTCCTCCTAG 8
32 mAD ATGGTAAATGACTTGTATTTATTAGATATCGAATAGTCTCTGTGGTGATTTTCCTCCTAG 8
33 mAD GCTATTCAAATAAACATGTATTCCTCATTCGATGAGGAAAATTTCTCTTTCTAGGAGGCT 13
34 sAD GCTATTCAAATAAACATGTATTCCTCATTCGATGAGGAAAATTTCTCTTTCTAGGAGGCT 13
35 sAD GCCCACTAAATAGTAATATTAGGATCTATCGATGAGAAAGATAAAAAGGAGGAGGAGGAA 9
36 mAD GCCCACTAAATAGTAATATTAGGATCTATCGATGAGAAAGATAAAAAGGAGGAGGAGGAA 9
37 sAD GTCATCAATATAAAAATTATTAATGCAATCGACTCTTAAATAATCTGAAAGTACTACTTC 9
38 mAD GTCATCAATATAAAAATTATTAATGCAATCGACTCTTAAATAATCTGAAAGTACTACTTC 9
39 sAD AAAATAGTATATATTCACTCTAGAAAATTCGAAGCAACAGCAAAACTGTGAAATAGATCC X
40 mAD AAAATAGTATATATTCACTCTAGAAAATTCGAAGCAACAGCAAAACTGTGAAATAGATCC X
41 mAD ATGTAAAGAATTTAAAAATAATCAGTTGTCGAAAGTCTGTTTGGGAACAGTGAAGTGAAC 18
42 sAD ATGTAAAGAATTTAAAAATAATCAGTTGTCGAAAGTCTGTTTGGGAACAGTGAAGTGAAC 18
43 sAD TTCTTGACTAAGTTTAGATATGCAAAATTCGAAAAGATCAATAGAAATGGGCAGAAATGT 1
44 mAD TTCTTGACTAAGTTTAGATATGCAAAATTCGAAAAGATCAATAGAAATGGGCAGAAATGT 1
45 sAD ATTAGAGAAGCAAAATTCTTCTCTACTTTCGAAAAACATATTGGATTGGTTTTTTCTTCA 10
46 mAD ATTAGAGAAGCAAAATTCTTCTCTACTTTCGAAAAACATATTGGATTGGTTTTTTCTTCA 10
47 sAD GTGAAATCCATGACTTTGAAGTCATTTTTCGAGGGATTTAAGCGAAATAGATTTATATAA 14
48 mAD GTGAAATCCATGACTTTGAAGTCATTTTTCGAGGGATTTAAGCGAAATAGATTTATATAA 14
49 mAD CGTAATGTTATTTTTAAAAACGTACTTTTCGAGTATCCAATGTATTAACCACCCCTTTAT 18
50 sAD CGTAATGTTATTTTTAAAAACGTACTTTTCGAGTATCCAATGTATTAACCACCCCTTTAT 18
51 mAD ATAATGTATAACACAAAATGTAAGAAGATCGAAGTTGAGTTGGAAATGCTTGGTGCATCA 20
52 sAD ATAATGTATAACACAAAATGTAAGAAGATCGAAGTTGAGTTGGAAATGCTTGGTGCATCA 20
53 sAD GATAGAAAAAAAGGAATATATTATCAACTCGAATTTCTGTCACCATTAGTCGTGAGACTT 4
54 mAD GATAGAAAAAAAGGAATATATTATCAACTCGAATTTCTGTCACCATTAGTCGTGAGACTT 4
55 sAD CTTATTTTCTGTAAACTGAAAATTAGAGTCGAAAACATACATTGTTGTGAAAGTAAAATA 3
56 mAD CTTATTTTCTGTAAACTGAAAATTAGAGTCGAAAACATACATTGTTGTGAAAGTAAAATA 3
57 sAD ATTTTACAAATGGTTTGCAAATTCTATTTCGAAACCTGAATCACAGAATTAGGCTTGACT 2
58 mAD ATTTTACAAATGGTTTGCAAATTCTATTTCGAAACCTGAATCACAGAATTAGGCTTGACT 2
59 sAD ATGTATTTTTCACAATATGAATTAAAAGTCGACTCATTTTCATCTGAAAAGCCTGTTTAG 10
60 mAD ATGTATTTTTCACAATATGAATTAAAAGTCGACTCATTTTCATCTGAAAAGCCTGTTTAG 10
61 sAD TATTTAGCTATAGTTTTTTCTCACTTTATCGAGATGATCAAAACGATCATAGCTATTTTG 10
62 mAD TATTTAGCTATAGTTTTTTCTCACTTTATCGAGATGATCAAAACGATCATAGCTATTTTG 10
63 sAD ATTTCCAGGTTAAAAAAAATAGAAGACATCGAGTAAGCTCTCCATGAATGTTGACTATTT 2
64 mAD ATTTCCAGGTTAAAAAAAATAGAAGACATCGAGTAAGCTCTCCATGAATGTTGACTATTT 2
65 sAD TAAACAAAATCTAGGAGGCCATTTTTTTTCGATTTTCATAAAACATTGTTCTTATTAAGG 5
66 mAD TAAACAAAATCTAGGAGGCCATTTTTTTTCGATTTTCATAAAACATTGTTCTTATTAAGG 5
67 mAD TAAGATAGAGAAATTGATTTTTAAAACTTCGATCATATGCTTAAAACTCCAGCCACAGTG 6
68 sAD TAAGATAGAGAAATTGATTTTTAAAACTTCGATCATATGCTTAAAACTCCAGCCACAGTG 6
69 sAD TTCGCTCTTGTTTTCTTTTTTATTTTTATCGAAAAATAAAAATAAAAAAGGAGTTTCTCA 6
70 mAD TTCGCTCTTGTTTTCTTTTTTATTTTTATCGAAAAATAAAAATAAAAAAGGAGTTTCTCA 6
71 mAD TGCCTTCTTTAGGTCGCTTCTGAGCGACTCGATTTATCACAGTACCAATCACCCTAACTA 6
72 sAD TGCCTTCTTTAGGTCGCTTCTGAGCGACTCGATTTATCACAGTACCAATCACCCTAACTA 6
73 sAD CACTTAGTAAGAGTTAATTGTTCATGTTTCGATAATAAGGAAATCCACTTCTAGAAGAGC 9
74 mAD CACTTAGTAAGAGTTAATTGTTCATGTTTCGATAATAAGGAAATCCACTTCTAGAAGAGC 9
75 sAD CAAACATCAATAGAAAGTTTATAAGAAGTCGAAGCAATATTTAAAAGCTTAGAGGATGTT 9
76 mAD CAAACATCAATAGAAAGTTTATAAGAAGTCGAAGCAATATTTAAAAGCTTAGAGGATGTT 9
77 sAD CCCTTTAAAACTCTTAAATATATTGTATTCGACAAAAAGTTCACAAAGAATGTAGCTTAA 1
78 mAD CCCTTTAAAACTCTTAAATATATTGTATTCGACAAAAAGTTCACAAAGAATGTAGCTTAA 1
79 sAD TGTAAAGAAAACAACGGTTGTTTTCAAGTCGATTTACCTCCTGGATCTTGTTTTCTCATC 10
80 mAD TGTAAAGAAAACAACGGTTGTTTTCAAGTCGATTTACCTCCTGGATCTTGTTTTCTCATC 10
81 sAD TTTTTTTTCATTTTTATTTTCAGAAGTATCGATTGCACAGAAATCTTCACATCACATCTT 2
82 mAD TTTTTTTTCATTTTTATTTTCAGAAGTATCGATTGCACAGAAATCTTCACATCACATCTT 2
83 sAD TTAATCTACTCTCTATCTGTGTAGATTCTCGAAATAATTCATGTCATTCACTTCAAAGAC 22
84 mAD TTAATCTACTCTCTATCTGTGTAGATTCTCGAAATAATTCATGTCATTCACTTCAAAGAC 22
85 sAD ATTAAAATATAAAATGGTAAATGTCATCTCGAATTCTTTCCTCTGAGGAGGCAAGAATTG 21
86 mAD ATTAAAATATAAAATGGTAAATGTCATCTCGAATTCTTTCCTCTGAGGAGGCAAGAATTG 21
87 mAD TATTACAGAAAAAAAAAAATGGATCTCTTCGATAAAAATGTACTTCAAAAATTGGATTGG 5
88 sAD TATTACAGAAAAAAAAAAATGGATCTCTTCGATAAAAATGTACTTCAAAAATTGGATTGG 5
89 sAD TATGAAAATATAAAAGAATATAAAGAGTTCGAGATCAGATTTAAAAGACAGACAATTCCA 7
90 mAD TATGAAAATATAAAAGAATATAAAGAGTTCGAGATCAGATTTAAAAGACAGACAATTCCA 7
91 sAD CTTCTGTTTTTATGCAGATTTAATGCAGTCGATTTACTTTTGTTTTAAAACAATTGACAA 2
92 mAD CTTCTGTTTTTATGCAGATTTAATGCAGTCGATTTACTTTTGTTTTAAAACAATTGACAA 2
93 sAD TTTTAAATTTTTATTATGATTATTATTTTCGATTTATTTAAACCTGTCTCCTCACAAGAA 9
94 mAD TTTTAAATTTTTATTATGATTATTATTTTCGATTTATTTAAACCTGTCTCCTCACAAGAA 9
95 sAD AGGCTATTTCTAGAAATAAGTATTGCCATCGAGTTACTTTCCTGATTCATTGCTCTTAGG 4
96 mAD AGGCTATTTCTAGAAATAAGTATTGCCATCGAGTTACTTTCCTGATTCATTGCTCTTAGG 4
97 sAD TGTTGTGAACTTTTGAAACAAATTTGTTTCGAATCTGAGTGTATATTTCTTATCAAGTCA 6
98 mAD TGTTGTGAACTTTTGAAACAAATTTGTTTCGAATCTGAGTGTATATTTCTTATCAAGTCA 6
99 sAD TATGATGAAGGATCAAGATTCTATAACATCGAAAAACTACCTATTGAGTACTATGTTTAC X
100 mAD TATGATGAAGGATCAAGATTCTATAACATCGAAAAACTACCTATTGAGTACTATGTTTAC X
101 sAD CTGTGGGAAATTTCTTTCTTTTTCTTTTTCGACCCTTTCAGTGTTCTTCCATTCTCTCTG 3
102 mAD CTGTGGGAAATTTCTTTCTTTTTCTTTTTCGACCCTTTCAGTGTTCTTCCATTCTCTCTG 3
103 sAD GATAGAAAAAAAGGAATATATTATCAACTCGAAGGGTCCTGAATACAAAGGTAAATAAAA 4
104 mAD GATAGAAAAAAAGGAATATATTATCAACTCGAAGGGTCCTGAATACAAAGGTAAATAAAA 4
105 sAD TTTCTTGTATTTCATTATGTACATCTATTCGATGTCAGTGTCCATCAATGGATAAATGGA 6
106 mAD TTTCTTGTATTTCATTATGTACATCTATTCGATGTCAGTGTCCATCAATGGATAAATGGA 6
107 sAD ATTAATTTCTTCCCCCTAGTTTCTTATTTCGAATTATTTAGATGATTGTCTCAATATTCC 10
108 mAD ATTAATTTCTTCCCCCTAGTTTCTTATTTCGAATTATTTAGATGATTGTCTCAATATTCC 10
109 sAD GAAGTTTCAACTTGATTCTTTCTAACTTTCGATATTACTCAATTCCAGTAGAAGATCCTC 11
110 mAD GAAGTTTCAACTTGATTCTTTCTAACTTTCGATATTACTCAATTCCAGTAGAAGATCCTC 11
表3.a5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
1 10186674 10186705 10224399 10224430 12 10186674 10190675 10220429 10224430
2 10186674 10186705 10224399 10224430 12 10186674 10190675 10220429 10224430
3 31073818 31073849 31106508 31106539 13 31073818 31077819 31102538 31106539
4 31073818 31073849 31106508 31106539 13 31073818 31077819 31102538 31106539
5 64424976 64425007 64473587 64473618 14 64424976 64428977 64469617 64473618
6 64424976 64425007 64473587 64473618 14 64424976 64428977 64469617 64473618
7 227782602 227782633 227796550 227796581 2 227778632 227782633 227792580 227796581
8 227782602 227782633 227796550 227796581 2 227778632 227782633 227792580 227796581
9 19898126 19898157 19917735 19917766 20 19898126 19902127 19917735 19921736
10 19898126 19898157 19917735 19917766 20 19898126 19902127 19917735 19921736
11 41745942 41745973 41782306 41782337 7 41741972 41745973 41778336 41782337
12 41745942 41745973 41782306 41782337 7 41741972 41745973 41778336 41782337
13 41782337 41782368 41811434 41811465 7 41782337 41786338 41811434 41815435
14 41782337 41782368 41811434 41811465 7 41782337 41786338 41811434 41815435
15 28475847 28475878 28490463 28490494 8 28471877 28475878 28486493 28490494
16 28475847 28475878 28490463 28490494 8 28471877 28475878 28486493 28490494
17 14268505 14268536 14331424 14331455 10 14268505 14272506 14331424 14335425
18 14268505 14268536 14331424 14331455 10 14268505 14272506 14331424 14335425
19 108858787 108858818 108890175 108890206 11 108858787 108862788 108886205 108890206
20 108858787 108858818 108890175 108890206 11 108858787 108862788 108886205 108890206
21 51332632 51332663 51385952 51385983 13 51328662 51332663 51385952 51389953
22 51332632 51332663 51385952 51385983 13 51328662 51332663 51385952 51389953
23 39591283 39591314 39623225 39623256 2 39591283 39595284 39623225 39627226
24 39591283 39591314 39623225 39623256 2 39591283 39595284 39623225 39627226
25 16442257 16442288 16503503 16503534 4 16442257 16446258 16503503 16507504
26 16442257 16442288 16503503 16503534 4 16442257 16446258 16503503 16507504
27 149369217 149369248 149424559 149424590 6 149365247 149369248 149420589 149424590
28 149369217 149369248 149424559 149424590 6 149365247 149369248 149420589 149424590
29 10137237 10137268 10233369 10233400 8 10137237 10141238 10229399 10233400
30 10137237 10137268 10233369 10233400 8 10137237 10141238 10229399 10233400
31 93946017 93946048 93985677 93985708 8 93942047 93946048 93985677 93989678
32 93946017 93946048 93985677 93985708 8 93942047 93946048 93985677 93989678
33 45859224 45859255 45940546 45940577 13 45859224 45863225 45940546 45944547
34 45859224 45859255 45940546 45940577 13 45859224 45863225 45940546 45944547
35 28339600 28339631 28366972 28367003 9 28335630 28339631 28363002 28367003
36 28339600 28339631 28366972 28367003 9 28335630 28339631 28363002 28367003
37 68359355 68359386 68383368 68383399 9 68359355 68363356 68379398 68383399
38 68359355 68359386 68383368 68383399 9 68359355 68363356 68379398 68383399
39 115396192 115396223 115457546 115457577 X 115396192 115400193 115453576 115457577
40 115396192 115396223 115457546 115457577 X 115396192 115400193 115453576 115457577
41 9948485 9948516 9986308 9986339 18 9944515 9948516 9986308 9990309
42 9948485 9948516 9986308 9986339 18 9944515 9948516 9986308 9990309
43 213940736 213940767 214000960 214000991 1 213940736 213944737 214000960 214004961
44 213940736 213940767 214000960 214000991 1 213940736 213944737 214000960 214004961
45 10920335 10920366 10937976 10938007 10 10920335 10924336 10934006 10938007
46 10920335 10920366 10937976 10938007 10 10920335 10924336 10934006 10938007
47 51872356 51872387 51939308 51939339 14 51872356 51876357 51935338 51939339
48 51872356 51872387 51939308 51939339 14 51872356 51876357 51935338 51939339
49 58217905 58217936 58260024 58260055 18 58213935 58217936 58260024 58264025
50 58217905 58217936 58260024 58260055 18 58213935 58217936 58260024 58264025
51 59935097 59935128 59974481 59974512 20 59931127 59935128 59974481 59978482
52 59935097 59935128 59974481 59974512 20 59931127 59935128 59974481 59978482
53 84803582 84803613 84849928 84849959 4 84799612 84803613 84849928 84853929
54 84803582 84803613 84849928 84849959 4 84799612 84803613 84849928 84853929
55 152326252 152326283 152344695 152344726 3 152322282 152326283 152344695 152348696
56 152326252 152326283 152344695 152344726 3 152322282 152326283 152344695 152348696
57 104433140 104433171 104477994 104478025 2 104433140 104437141 104474024 104478025
58 104433140 104433171 104477994 104478025 2 104433140 104437141 104474024 104478025
59 121570719 121570750 121596903 121596934 10 121566749 121570750 121592933 121596934
60 121570719 121570750 121596903 121596934 10 121566749 121570750 121592933 121596934
61 23013442 23013473 23075372 23075403 10 23009472 23013473 23071402 23075403
62 23013442 23013473 23075372 23075403 10 23009472 23013473 23071402 23075403
63 41848834 41848865 41957495 41957526 2 41844864 41848865 41953525 41957526
64 41848834 41848865 41957495 41957526 2 41844864 41848865 41953525 41957526
65 39079109 39079140 39150069 39150100 5 39079109 39083110 39146099 39150100
66 39079109 39079140 39150069 39150100 5 39079109 39083110 39146099 39150100
67 134196714 134196745 134322425 134322456 6 134192744 134196745 134322425 134326426
68 134196714 134196745 134322425 134322456 6 134192744 134196745 134322425 134326426
69 36576177 36576208 36625118 36625149 6 36576177 36580178 36621148 36625149
70 36576177 36576208 36625118 36625149 6 36576177 36580178 36621148 36625149
71 84775145 84775176 84804896 84804927 6 84775145 84779146 84804896 84808897
72 84775145 84775176 84804896 84804927 6 84775145 84779146 84804896 84808897
73 120677837 120677868 120725114 120725145 9 120673867 120677868 120725114 120729115
74 120677837 120677868 120725114 120725145 9 120673867 120677868 120725114 120729115
75 92403506 92403537 92441238 92441269 9 92403506 92407507 92437268 92441269
76 92403506 92403537 92441238 92441269 9 92403506 92407507 92437268 92441269
77 159074759 159074790 159117264 159117295 1 159074759 159078760 159117264 159121265
78 159074759 159074790 159117264 159117295 1 159074759 159078760 159117264 159121265
79 112983990 112984021 112999906 112999937 10 112983990 112987991 112999906 113003907
80 112983990 112984021 112999906 112999937 10 112983990 112987991 112999906 113003907
81 104413887 104413918 104466236 104466267 2 104409917 104413918 104466236 104470237
82 104413887 104413918 104466236 104466267 2 104409917 104413918 104466236 104470237
83 26757531 26757562 26817002 26817033 22 26753561 26757562 26817002 26821003
84 26757531 26757562 26817002 26817033 22 26753561 26757562 26817002 26821003
85 40396097 40396128 40423687 40423718 21 40396097 40400098 40423687 40427688
86 40396097 40396128 40423687 40423718 21 40396097 40400098 40423687 40427688
87 7542352 7542383 7606244 7606275 5 7538382 7542383 7606244 7610245
88 7542352 7542383 7606244 7606275 5 7538382 7542383 7606244 7610245
89 28717278 28717309 28769795 28769826 7 28717278 28721279 28769795 28773796
90 28717278 28717309 28769795 28769826 7 28717278 28721279 28769795 28773796
91 235136683 235136714 235201293 235201324 2 235136683 235140684 235197323 235201324
92 235136683 235136714 235201293 235201324 2 235136683 235140684 235197323 235201324
93 131592737 131592768 131654389 131654420 9 131588767 131592768 131654389 131658390
94 131592737 131592768 131654389 131654420 9 131588767 131592768 131654389 131658390
95 16876772 16876803 16933477 16933508 4 16872802 16876803 16929507 16933508
96 16876772 16876803 16933477 16933508 4 16872802 16876803 16929507 16933508
97 115984820 115984851 116027406 116027437 6 115980850 115984851 116027406 116031407
98 115984820 115984851 116027406 116027437 6 115980850 115984851 116027406 116031407
99 11308524 11308555 11364232 11364263 X 11308524 11312525 11364232 11368233
100 11308524 11308555 11364232 11364263 X 11308524 11312525 11364232 11368233
101 58504352 58504383 58624445 58624476 3 58500382 58504383 58624445 58628446
102 58504352 58504383 58624445 58624476 3 58500382 58504383 58624445 58628446
103 84803582 84803613 84853916 84853947 4 84799612 84803613 84853916 84857917
104 84803582 84803613 84853916 84853947 4 84799612 84803613 84853916 84857917
105 73690117 73690148 73720087 73720118 6 73686147 73690148 73720087 73724088
106 73690117 73690148 73720087 73720118 6 73686147 73690148 73720087 73724088
107 14331424 14331455 14346291 14346322 10 14331424 14335425 14346291 14350292
108 14331424 14331455 14346291 14346322 10 14331424 14335425 14346291 14350292
109 87934295 87934326 87969207 87969238 11 87930325 87934326 87969207 87973208
110 87934295 87934326 87969207 87969238 11 87930325 87934326 87969207 87973208
表3.a6
   探針 PCR- 引子 1_ID PCR_ 引子 1
1 ORF1_12_10186674_10187896_10218366_10224430_RF OBD159_1361 GCTGTGTCTCTCCCAGGTAGGCT
2 ORF1_12_10186674_10187896_10218366_10224430_RF OBD159_1361 GCTGTGTCTCTCCCAGGTAGGCT
3 ORF1_13_31073818_31075538_31104522_31106539_RF OBD159_1365 CTGCTTCCACGGGCATAACCCAT
4 ORF1_13_31073818_31075538_31104522_31106539_RF OBD159_1365 CTGCTTCCACGGGCATAACCCAT
5 ORF1_14_64424976_64426071_64470387_64473618_RF OBD159_1369 CATCCATACATTTCTAACTTCATC
6 ORF1_14_64424976_64426071_64470387_64473618_RF OBD159_1369 CATCCATACATTTCTAACTTCATC
7 ORF1_2_227779837_227782633_227794345_227796581_FF OBD159_1373 GGATGTCCAAGACTCTGCTGCTG
8 ORF1_2_227779837_227782633_227794345_227796581_FF OBD159_1373 GGATGTCCAAGACTCTGCTGCTG
9 ORF1_20_19898126_19900554_19917735_19921318_RR OBD159_1377 AGAAGTCCCCTGGCGAAGATGAGCAT
10 ORF1_20_19898126_19900554_19917735_19921318_RR OBD159_1377 AGAAGTCCCCTGGCGAAGATGAGCAT
11 ORF1_7_41740758_41745973_41778759_41782337_FF OBD159_1381 GGCTACTCCACAGGCAGAGCAGC
12 ORF1_7_41740758_41745973_41778759_41782337_FF OBD159_1381 GGCTACTCCACAGGCAGAGCAGC
13 ORF1_7_41782337_41783687_41811434_41814240_RR OBD159_1385 CTTCATCTAAACTTCACAGGCAAAAG
14 ORF1_7_41782337_41783687_41811434_41814240_RR OBD159_1385 CTTCATCTAAACTTCACAGGCAAAAG
15 ORF1_8_28471461_28475878_28486639_28490494_FF OBD159_1389 GTTCACGCTTCACTTAGACCTTACAG
16 ORF1_8_28471461_28475878_28486639_28490494_FF OBD159_1389 GTTCACGCTTCACTTAGACCTTACAG
17 ORF10_10_14268505_14273692_14331424_14334008_RR OBD159_1393 AGTCCTTGGCAGGTAGGTAGCAT
18 ORF10_10_14268505_14273692_14331424_14334008_RR OBD159_1393 AGTCCTTGGCAGGTAGGTAGCAT
19 ORF10_11_108858787_108864679_108885482_108890206_RF OBD159_1397 GTATTTGGTAGTTTTACTGTGTCTCC
20 ORF10_11_108858787_108864679_108885482_108890206_RF OBD159_1397 GTATTTGGTAGTTTTACTGTGTCTCC
21 ORF10_13_51326485_51332663_51385952_51389062_FR OBD159_1401 GTCCCCAGCATTTGTGATGTCCCCAA
22 ORF10_13_51326485_51332663_51385952_51389062_FR OBD159_1401 GTCCCCAGCATTTGTGATGTCCCCAA
23 ORF10_2_39591283_39594585_39623225_39627003_RR OBD159_1405 GGAGCAGGTTTATGGCTTCCAGG
24 ORF10_2_39591283_39594585_39623225_39627003_RR OBD159_1405 GGAGCAGGTTTATGGCTTCCAGG
25 ORF10_4_16442257_16447221_16503503_16507970_RR OBD159_1409 GCACGATTACCCCTTTATTCCAGACT
26 ORF10_4_16442257_16447221_16503503_16507970_RR OBD159_1409 GCACGATTACCCCTTTATTCCAGACT
27 ORF10_6_149361564_149369248_149422330_149424590_FF OBD159_1413 TTATTGAGCACTGAGGAGTTCTAT
28 ORF10_6_149361564_149369248_149422330_149424590_FF OBD159_1413 TTATTGAGCACTGAGGAGTTCTAT
29 ORF10_8_10137237_10138418_10231545_10233400_RF OBD159_1417 GCTTCTCTCTTCTTGCCTTCTGCCCA
30 ORF10_8_10137237_10138418_10231545_10233400_RF OBD159_1417 GCTTCTCTCTTCTTGCCTTCTGCCCA
31 ORF10_8_93942397_93946048_93985677_93987921_FR OBD159_1421 GCCCTCTTAGATTGATGCCAGAAGTA
32 ORF10_8_93942397_93946048_93985677_93987921_FR OBD159_1421 GCCCTCTTAGATTGATGCCAGAAGTA
33 ORF100_13_45859224_45860475_45940546_45944992_RR OBD159_1425 CTGCCCTCTTCCTTTCCCTCCTGTAT
34 ORF100_13_45859224_45860475_45940546_45944992_RR OBD159_1425 CTGCCCTCTTCCTTTCCCTCCTGTAT
35 ORF102_9_28333777_28339631_28362689_28367003_FF OBD159_1429 GCCTAAGTCCAGTAGTATGGTGGCTG
36 ORF102_9_28333777_28339631_28362689_28367003_FF OBD159_1429 GCCTAAGTCCAGTAGTATGGTGGCTG
37 ORF102_9_68359355_68363452_68378236_68383399_RF OBD159_1433 GGTGCTACACTCTAAGGCAGCGT
38 ORF102_9_68359355_68363452_68378236_68383399_RF OBD159_1433 GGTGCTACACTCTAAGGCAGCGT
39 ORF102_X_115396192_115405592_115455128_115457577_RF OBD159_1437 CCCTCAACACTGCTCCTCCAAGA
40 ORF102_X_115396192_115405592_115455128_115457577_RF OBD159_1437 CCCTCAACACTGCTCCTCCAAGA
41 ORF103_18_9946347_9948516_9986308_9994472_FR OBD159_1441 TTTGGCAAGGCATAGAATAGAATA
42 ORF103_18_9946347_9948516_9986308_9994472_FR OBD159_1441 TTTGGCAAGGCATAGAATAGAATA
43 ORF104_1_213940736_213945091_214000960_214005699_RR OBD159_1445 TAAAGACAGGCTTGTGCCAGAAAT
44 ORF104_1_213940736_213945091_214000960_214005699_RR OBD159_1445 TAAAGACAGGCTTGTGCCAGAAAT
45 ORF105_10_10920335_10921487_10936753_10938007_RF OBD159_1449 GGAGGGAGGGAAAGAGGGACTATGAA
46 ORF105_10_10920335_10921487_10936753_10938007_RF OBD159_1449 GGAGGGAGGGAAAGAGGGACTATGAA
47 ORF105_14_51872356_51878662_51935246_51939339_RF OBD159_1453 TTTTCCGTGGAGTGAACAAAGCCCA
48 ORF105_14_51872356_51878662_51935246_51939339_RF OBD159_1453 TTTTCCGTGGAGTGAACAAAGCCCA
49 ORF106_18_58215328_58217936_58260024_58262426_FR OBD159_1457 TGTAGAGCCAAATAGCCACAGGGATA
50 ORF106_18_58215328_58217936_58260024_58262426_FR OBD159_1457 TGTAGAGCCAAATAGCCACAGGGATA
51 ORF106_20_59933715_59935128_59974481_59977463_FR OBD159_1461 CTCAGTTGTGGACCAGAGCAGAT
52 ORF106_20_59933715_59935128_59974481_59977463_FR OBD159_1461 CTCAGTTGTGGACCAGAGCAGAT
53 ORF106_4_84797792_84803613_84849928_84853393_FR OBD159_1465 ATGGCTCCAGGATGAATGATGACTGC
54 ORF106_4_84797792_84803613_84849928_84853393_FR OBD159_1465 ATGGCTCCAGGATGAATGATGACTGC
55 ORF107_3_152324462_152326283_152344695_152347512_FR OBD159_1469 GTTCAACTTTTCCTGATTGTCACAGC
56 ORF107_3_152324462_152326283_152344695_152347512_FR OBD159_1469 GTTCAACTTTTCCTGATTGTCACAGC
57 ORF109_2_104433140_104437833_104474480_104478025_RF OBD159_1473 ATTTACATTCCTCCACTTCATTTA
58 ORF109_2_104433140_104437833_104474480_104478025_RF OBD159_1473 ATTTACATTCCTCCACTTCATTTA
59 ORF11_10_121564423_121570750_121595209_121596934_FF OBD159_1477 GGAGAAGGTTCCAGAAGCCGCCT
60 ORF11_10_121564423_121570750_121595209_121596934_FF OBD159_1477 GGAGAAGGTTCCAGAAGCCGCCT
61 ORF11_10_23011505_23013473_23072347_23075403_FF OBD159_1481 GGAATAGCCTTGCTTGTTTTGTGGCA
62 ORF11_10_23011505_23013473_23072347_23075403_FF OBD159_1481 GGAATAGCCTTGCTTGTTTTGTGGCA
63 ORF11_2_41846751_41848865_41954493_41957526_FF OBD159_1485 GGGCTTCCAGACATAAGACACAACTA
64 ORF11_2_41846751_41848865_41954493_41957526_FF OBD159_1485 GGGCTTCCAGACATAAGACACAACTA
65 ORF11_5_39079109_39081309_39147583_39150100_RF OBD159_1489 ATTCTCCTTTGCCCCTTCTCCTCCTC
66 ORF11_5_39079109_39081309_39147583_39150100_RF OBD159_1489 ATTCTCCTTTGCCCCTTCTCCTCCTC
67 ORF11_6_134192786_134196745_134322425_134324942_FR OBD159_1493 CTGAGAATGATTGTGGTTACCTGTTC
68 ORF11_6_134192786_134196745_134322425_134324942_FR OBD159_1493 CTGAGAATGATTGTGGTTACCTGTTC
69 ORF11_6_36576177_36578246_36622186_36625149_RF OBD159_1497 GGCAGTCTTCATTCTTGGCTCTA
70 ORF11_6_36576177_36578246_36622186_36625149_RF OBD159_1497 GGCAGTCTTCATTCTTGGCTCTA
71 ORF11_6_84775145_84786636_84804896_84812997_RR OBD159_1501 AGTCTATCTCGTGGAGGTTCGGC
72 ORF11_6_84775145_84786636_84804896_84812997_RR OBD159_1501 AGTCTATCTCGTGGAGGTTCGGC
73 ORF11_9_120675206_120677868_120725114_120727254_FR OBD159_1505 TTGTGCCACCACTTTTCCATTAGTAT
74 ORF11_9_120675206_120677868_120725114_120727254_FR OBD159_1505 TTGTGCCACCACTTTTCCATTAGTAT
75 ORF110_9_92403506_92407832_92438750_92441269_RF OBD159_1509 TCATACTTTTGGATGTTACTTACA
76 ORF110_9_92403506_92407832_92438750_92441269_RF OBD159_1509 TCATACTTTTGGATGTTACTTACA
77 ORF111_1_159074759_159077481_159117264_159124296_RR OBD159_1513 CCCTTTGAGATTTTGGATAGGAGTTT
78 ORF111_1_159074759_159077481_159117264_159124296_RR OBD159_1513 CCCTTTGAGATTTTGGATAGGAGTTT
79 ORF112_10_112983990_112985695_112999906_113005525_RR OBD159_1517 GGGAAAGTCTATTGACCAACACTGCT
80 ORF112_10_112983990_112985695_112999906_113005525_RR OBD159_1517 GGGAAAGTCTATTGACCAACACTGCT
81 ORF112_2_104411249_104413918_104466236_104469082_FR OBD159_1521 CGGTAGACACCTCTTTTCCCTGC
82 ORF112_2_104411249_104413918_104466236_104469082_FR OBD159_1521 CGGTAGACACCTCTTTTCCCTGC
83 ORF112_22_26756491_26757562_26817002_26819259_FR OBD159_1525 GCAATCCCTCCAGCCCTTGTCAATCA
84 ORF112_22_26756491_26757562_26817002_26819259_FR OBD159_1525 GCAATCCCTCCAGCCCTTGTCAATCA
85 ORF113_21_40396097_40402350_40423687_40428489_RR OBD159_1529 GGTGAGACATAGTAGCAAGGAAGAGG
86 ORF113_21_40396097_40402350_40423687_40428489_RR OBD159_1529 GGTGAGACATAGTAGCAAGGAAGAGG
87 ORF113_5_7540900_7542383_7606244_7610178_FR OBD159_1533 AATCTGAACTTAGACAGGCTGGCTGC
88 ORF113_5_7540900_7542383_7606244_7610178_FR OBD159_1533 AATCTGAACTTAGACAGGCTGGCTGC
89 ORF113_7_28717278_28719857_28769795_28772438_RR OBD159_1537 GCTAACCACCAGAGTCACACACATCA
90 ORF113_7_28717278_28719857_28769795_28772438_RR OBD159_1537 GCTAACCACCAGAGTCACACACATCA
91 ORF115_2_235136683_235138232_235199086_235201324_RF OBD159_1541 CACACCTACAAGTATTTTAGTTTA
92 ORF115_2_235136683_235138232_235199086_235201324_RF OBD159_1541 CACACCTACAAGTATTTTAGTTTA
93 ORF115_9_131590628_131592768_131654389_131655808_FR OBD159_1545 CTGTTCAAACCCGTCAGCAGGAT
94 ORF115_9_131590628_131592768_131654389_131655808_FR OBD159_1545 CTGTTCAAACCCGTCAGCAGGAT
95 ORF117_4_16871472_16876803_16929111_16933508_FF OBD159_1549 ATCCCTACCAACAGTAATCAGCAAAA
96 ORF117_4_16871472_16876803_16929111_16933508_FF OBD159_1549 ATCCCTACCAACAGTAATCAGCAAAA
97 ORF117_6_115981175_115984851_116027406_116036226_FR OBD159_1553 TGCCATTCACACAAAGTCTAAGGG
98 ORF117_6_115981175_115984851_116027406_116036226_FR OBD159_1553 TGCCATTCACACAAAGTCTAAGGG
99 ORF117_X_11308524_11309949_11364232_11365389_RR OBD159_1557 GGAGTGTCTCTTTGGGTCTCAATCAT
100 ORF117_X_11308524_11309949_11364232_11365389_RR OBD159_1557 GGAGTGTCTCTTTGGGTCTCAATCAT
101 ORF118_3_58502739_58504383_58624445_58628835_FR OBD159_1561 ACGCACTTAGGAGGATTGTGTGTGTG
102 ORF118_3_58502739_58504383_58624445_58628835_FR OBD159_1561 ACGCACTTAGGAGGATTGTGTGTGTG
103 ORF118_4_84797792_84803613_84853916_84860994_FR OBD159_1565 CTTCCTCTTCAGTTACTTTCATCCAC
104 ORF118_4_84797792_84803613_84853916_84860994_FR OBD159_1565 CTTCCTCTTCAGTTACTTTCATCCAC
105 ORF119_6_73688989_73690148_73720087_73722647_FR OBD159_1569 TCAGTGTTTGCTTTTCCCTTGAAT
106 ORF119_6_73688989_73690148_73720087_73722647_FR OBD159_1569 TCAGTGTTTGCTTTTCCCTTGAAT
107 ORF12_10_14331424_14334008_14346291_14350333_RR OBD159_1573 GATGAAGTCTTGCTATGTTGCCTA
108 ORF12_10_14331424_14334008_14346291_14350333_RR OBD159_1573 GATGAAGTCTTGCTATGTTGCCTA
109 ORF12_11_87926403_87934326_87969207_88006264_FR OBD159_1577 CCAATAACCTTCCAGCATCTCCCTGA
110 ORF12_11_87926403_87934326_87969207_88006264_FR OBD159_1577 CCAATAACCTTCCAGCATCTCCCTGA
表3.a7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
1 OBD159_1363 GCACCATCAGGCTTCTGGGAATG OBD159_1361_1363 0.000483127
2 OBD159_1363 GCACCATCAGGCTTCTGGGAATG OBD159_1361_1363 0.000483127
3 OBD159_1367 CCCACAGGGTTGGCAGTGAGATG OBD159_1365_1367 0.001975911
4 OBD159_1367 CCCACAGGGTTGGCAGTGAGATG OBD159_1365_1367 0.001975911
5 OBD159_1371 TTCTCTATTCTTCCCTTCCCTTTT OBD159_1369_1371 0.000206239
6 OBD159_1371 TTCTCTATTCTTCCCTTCCCTTTT OBD159_1369_1371 0.000206239
7 OBD159_1375 GGCACCCAGAGGCTCCTTTGGAA OBD159_1373_1375 0.000139185
8 OBD159_1375 GGCACCCAGAGGCTCCTTTGGAA OBD159_1373_1375 0.000139185
9 OBD159_1379 GCTGTGGACTGGGTAAATAAAGTGTG OBD159_1377_1379 0.000611043
10 OBD159_1379 GCTGTGGACTGGGTAAATAAAGTGTG OBD159_1377_1379 0.000611043
11 OBD159_1383 GCAGGGATGAGGATAGTAAACCAAT OBD159_1381_1383 0.001134506
12 OBD159_1383 GCAGGGATGAGGATAGTAAACCAAT OBD159_1381_1383 0.001134506
13 OBD159_1387 TTCATCACTCCTTTCATCTCACCAGC OBD159_1385_1387 0.001275093
14 OBD159_1387 TTCATCACTCCTTTCATCTCACCAGC OBD159_1385_1387 0.001275093
15 OBD159_1391 CTTAGGCAACAATGTGTGGGCTCCTG OBD159_1389_1391 0.000870192
16 OBD159_1391 CTTAGGCAACAATGTGTGGGCTCCTG OBD159_1389_1391 0.000870192
17 OBD159_1395 GAGATGAAGTCTTGCTATGTTGCCTA OBD159_1393_1395 0.000683889
18 OBD159_1395 GAGATGAAGTCTTGCTATGTTGCCTA OBD159_1393_1395 0.000683889
19 OBD159_1399 GCTGACAGGCAAGGTGAAAATCAACA OBD159_1397_1399 0.000831118
20 OBD159_1399 GCTGACAGGCAAGGTGAAAATCAACA OBD159_1397_1399 0.000831118
21 OBD159_1403 CCATAGAGGGTAGGTAGGACTTCAAT OBD159_1401_1403 0.002341565
22 OBD159_1403 CCATAGAGGGTAGGTAGGACTTCAAT OBD159_1401_1403 0.002341565
23 OBD159_1407 CCTGGCTGAAGACCTGGCTACTC OBD159_1405_1407 0.001148769
24 OBD159_1407 CCTGGCTGAAGACCTGGCTACTC OBD159_1405_1407 0.001148769
25 OBD159_1411 GGTTGCCTGTGTGGTGATAGGTGACA OBD159_1409_1411 0.001747902
26 OBD159_1411 GGTTGCCTGTGTGGTGATAGGTGACA OBD159_1409_1411 0.001747902
27 OBD159_1415 AAATCATCCCCAATCCAGAACTGA OBD159_1413_1415 0.000852496
28 OBD159_1415 AAATCATCCCCAATCCAGAACTGA OBD159_1413_1415 0.000852496
29 OBD159_1419 GGAATGAAACAGGGCACAGAATAAGG OBD159_1417_1419 0.00135607
30 OBD159_1419 GGAATGAAACAGGGCACAGAATAAGG OBD159_1417_1419 0.00135607
31 OBD159_1423 AACAGAGAGGCTGAGGTGCCCACATT OBD159_1421_1423 4.20E-05
32 OBD159_1423 AACAGAGAGGCTGAGGTGCCCACATT OBD159_1421_1423 4.20E-05
33 OBD159_1427 GGAGCAGAGACTTGAATACAATGAGG OBD159_1425_1427 0.001395875
34 OBD159_1427 GGAGCAGAGACTTGAATACAATGAGG OBD159_1425_1427 0.001395875
35 OBD159_1431 CTTATCAACAGGCTTACTCTCACCTC OBD159_1429_1431 -0.000169106
36 OBD159_1431 CTTATCAACAGGCTTACTCTCACCTC OBD159_1429_1431 -0.000169106
37 OBD159_1435 CCACCTTTCTCCTGAAGCCAGCC OBD159_1433_1435 0.001463436
38 OBD159_1435 CCACCTTTCTCCTGAAGCCAGCC OBD159_1433_1435 0.001463436
39 OBD159_1439 AGGAACCAGGCACCCATTCAGGG OBD159_1437_1439 0.000491367
40 OBD159_1439 AGGAACCAGGCACCCATTCAGGG OBD159_1437_1439 0.000491367
41 OBD159_1443 TCTAAACCCCACTGGTCATCTCAG OBD159_1441_1443 0.00197459
42 OBD159_1443 TCTAAACCCCACTGGTCATCTCAG OBD159_1441_1443 0.00197459
43 OBD159_1447 GTAGAATGGGTTGACCTGATAAGC OBD159_1445_1447 0.000659523
44 OBD159_1447 GTAGAATGGGTTGACCTGATAAGC OBD159_1445_1447 0.000659523
45 OBD159_1451 CTCTAAGTCCCTGAACACAGTAAGAA OBD159_1449_1451 0.000290692
46 OBD159_1451 CTCTAAGTCCCTGAACACAGTAAGAA OBD159_1449_1451 0.000290692
47 OBD159_1455 GGCATCACAGTGGACTCCCTCAAACA OBD159_1453_1455 0.000175588
48 OBD159_1455 GGCATCACAGTGGACTCCCTCAAACA OBD159_1453_1455 0.000175588
49 OBD159_1459 CCACCTTCGCCTCCTGTGTTGTTATG OBD159_1457_1459 0.002356539
50 OBD159_1459 CCACCTTCGCCTCCTGTGTTGTTATG OBD159_1457_1459 0.002356539
51 OBD159_1463 CACCCCACACTGTCACTCTTTGCTCT OBD159_1461_1463 0.002388817
52 OBD159_1463 CACCCCACACTGTCACTCTTTGCTCT OBD159_1461_1463 0.002388817
53 OBD159_1467 GGAAATGCTCCGCCGAATACAATGAC OBD159_1465_1467 0.00088211
54 OBD159_1467 GGAAATGCTCCGCCGAATACAATGAC OBD159_1465_1467 0.00088211
55 OBD159_1471 GTCTGTGTGTCTTTGTGTGCCTTTCC OBD159_1469_1471 0.000579193
56 OBD159_1471 GTCTGTGTGTCTTTGTGTGCCTTTCC OBD159_1469_1471 0.000579193
57 OBD159_1475 AGAAATCACCAACAGCAGAACCAT OBD159_1473_1475 0.001511766
58 OBD159_1475 AGAAATCACCAACAGCAGAACCAT OBD159_1473_1475 0.001511766
59 OBD159_1479 GCGTCCAATCAGAACTTGCGAGC OBD159_1477_1479 0.000720571
60 OBD159_1479 GCGTCCAATCAGAACTTGCGAGC OBD159_1477_1479 0.000720571
61 OBD159_1483 GAGAAGGGAGGTAAAATGTAATCAAC OBD159_1481_1483 0.000499411
62 OBD159_1483 GAGAAGGGAGGTAAAATGTAATCAAC OBD159_1481_1483 0.000499411
63 OBD159_1487 GTGGCTACACCCGAGAGGGAAACTAA OBD159_1485_1487 0.00241081
64 OBD159_1487 GTGGCTACACCCGAGAGGGAAACTAA OBD159_1485_1487 0.00241081
65 OBD159_1491 GGTGTCCTTATCAGTAAACAACTTCC OBD159_1489_1491 0.001400012
66 OBD159_1491 GGTGTCCTTATCAGTAAACAACTTCC OBD159_1489_1491 0.001400012
67 OBD159_1495 AATCCCCAGCAGGGTTTCCTAAT OBD159_1493_1495 0.001528487
68 OBD159_1495 AATCCCCAGCAGGGTTTCCTAAT OBD159_1493_1495 0.001528487
69 OBD159_1499 GATTCTTGGTTGTTGGCTGGGATTA OBD159_1497_1499 4.59E-05
70 OBD159_1499 GATTCTTGGTTGTTGGCTGGGATTA OBD159_1497_1499 4.59E-05
71 OBD159_1503 GGAGCAGGTGGACCATCTGTTCC OBD159_1501_1503 0.000940181
72 OBD159_1503 GGAGCAGGTGGACCATCTGTTCC OBD159_1501_1503 0.000940181
73 OBD159_1507 ACTGACTGATTTGGGTCTGATGGTGG OBD159_1505_1507 0.000811594
74 OBD159_1507 ACTGACTGATTTGGGTCTGATGGTGG OBD159_1505_1507 0.000811594
75 OBD159_1511 TAGTATGTCTGCTGAAGGCACTTA OBD159_1509_1511 0.001026187
76 OBD159_1511 TAGTATGTCTGCTGAAGGCACTTA OBD159_1509_1511 0.001026187
77 OBD159_1515 TTTCCTATCTTCCCACCTCTTCTGCC OBD159_1513_1515 0.001007363
78 OBD159_1515 TTTCCTATCTTCCCACCTCTTCTGCC OBD159_1513_1515 0.001007363
79 OBD159_1519 TCTCCAAGAGGCAACTGCTTAGACAG OBD159_1517_1519 0.00022376
80 OBD159_1519 TCTCCAAGAGGCAACTGCTTAGACAG OBD159_1517_1519 0.00022376
81 OBD159_1523 GTGCCTTCCACCAGAGTCCACATC OBD159_1521_1523 0.00106458
82 OBD159_1523 GTGCCTTCCACCAGAGTCCACATC OBD159_1521_1523 0.00106458
83 OBD159_1527 GCCAAGCAGGTTTTGATAATCCAAGG OBD159_1525_1527 0.000806912
84 OBD159_1527 GCCAAGCAGGTTTTGATAATCCAAGG OBD159_1525_1527 0.000806912
85 OBD159_1531 CTCCGCTCTTGGATTTCTGCCCATTA OBD159_1529_1531 0.000966015
86 OBD159_1531 CTCCGCTCTTGGATTTCTGCCCATTA OBD159_1529_1531 0.000966015
87 OBD159_1535 GGACATAAGCCCAAACAGGAACACTG OBD159_1533_1535 0.001252937
88 OBD159_1535 GGACATAAGCCCAAACAGGAACACTG OBD159_1533_1535 0.001252937
89 OBD159_1539 CCATCCCAGTTTCACCATTGGCAAGA OBD159_1537_1539 0.000426768
90 OBD159_1539 CCATCCCAGTTTCACCATTGGCAAGA OBD159_1537_1539 0.000426768
91 OBD159_1543 TTTAGAGCGGTGAGACAGTGACAC OBD159_1541_1543 0.00080326
92 OBD159_1543 TTTAGAGCGGTGAGACAGTGACAC OBD159_1541_1543 0.00080326
93 OBD159_1547 CCGCCCCAGCCTCCCAAAGTGCT OBD159_1545_1547 0.000288908
94 OBD159_1547 CCGCCCCAGCCTCCCAAAGTGCT OBD159_1545_1547 0.000288908
95 OBD159_1551 GGGATAGTTAGAAAGAGAAGATGAGA OBD159_1549_1551 0.001395559
96 OBD159_1551 GGGATAGTTAGAAAGAGAAGATGAGA OBD159_1549_1551 0.001395559
97 OBD159_1555 CTTTTGAATAGTTCTTACTTTATGC OBD159_1553_1555 0.001054768
98 OBD159_1555 CTTTTGAATAGTTCTTACTTTATGC OBD159_1553_1555 0.001054768
99 OBD159_1559 GGGTAGGCAACTAACTGAGGCTGCTA OBD159_1557_1559 0.000454783
100 OBD159_1559 GGGTAGGCAACTAACTGAGGCTGCTA OBD159_1557_1559 0.000454783
101 OBD159_1563 GGAAGGGAGAGTGCTGGACATTTCAT OBD159_1561_1563 0.00210011
102 OBD159_1563 GGAAGGGAGAGTGCTGGACATTTCAT OBD159_1561_1563 0.00210011
103 OBD159_1567 TTCCCACCCCAGGCATTCTCTTTCAG OBD159_1565_1567 0.000488724
104 OBD159_1567 TTCCCACCCCAGGCATTCTCTTTCAG OBD159_1565_1567 0.000488724
105 OBD159_1571 CTGAAAATGACAAGACCTCCTTCT OBD159_1569_1571 -1.93E-05
106 OBD159_1571 CTGAAAATGACAAGACCTCCTTCT OBD159_1569_1571 -1.93E-05
107 OBD159_1575 TTGCCATCTCTTTGTTCAAGTTTT OBD159_1573_1575 0.003218258
108 OBD159_1575 TTGCCATCTCTTTGTTCAAGTTTT OBD159_1573_1575 0.003218258
109 OBD159_1579 CCAACTGTGCCAAAGGATGATGATGG OBD159_1577_1579 0.00255055
110 OBD159_1579 CCAACTGTGCCAAAGGATGATGATGG OBD159_1577_1579 0.00255055
表3.a8
   基因
1 GABARAPL1; KLRD1; TMEM52B
2 GABARAPL1; KLRD1; TMEM52B
3 HSPH1; TEX26
4 HSPH1; TEX26
5 AKAP5; MTHFD1; ZBTB25; rs34181110; rs2236225; rs2281603; rs17824591
6 AKAP5; MTHFD1; ZBTB25; rs34181110; rs2236225; rs2281603; rs17824591
7 rs7556897; rs4973341; rs1811711
8 rs7556897; rs4973341; rs1811711
9 RIN2; rs181853315
10 RIN2; rs181853315
11 INHBA; rs6976118
12 INHBA; rs6976118
13 INHBA; rs6976118
14 INHBA; rs6976118
15 FBXO16; FZD3
16 FBXO16; FZD3
17 FRMD4A; rs1218412; rs12220909
18 FRMD4A; rs1218412; rs12220909
19 DDX10; rs10890917
20 DDX10; rs10890917
21 FAM124A; INTS6; SERPINE3
22 FAM124A; INTS6; SERPINE3
23 MAP4K3; TMEM178A
24 MAP4K3; TMEM178A
25 LDB2; rs10939673
26 LDB2; rs10939673
27 SUMO4; TAB2; rs267607101; rs267607100; rs1057518422; rs237025; rs2153219
28 SUMO4; TAB2; rs267607101; rs267607100; rs1057518422; rs237025; rs2153219
29 MSRA; rs10107815; rs73191547; rs17749155; rs2975735; rs7001567
30 MSRA; rs10107815; rs73191547; rs17749155; rs2975735; rs7001567
31 PDP1; rs7006531
32 PDP1; rs7006531
33 SIAH3; ZC3H13
34 SIAH3; ZC3H13
35 LINGO2; rs7851437
36 LINGO2; rs7851437
37 FOXD4L3; PGM5
38 FOXD4L3; PGM5
39 LUZP4; PLS3
40 LUZP4; PLS3
41 TXNDC2; VAPA; rs29067; rs29066
42 TXNDC2; VAPA; rs29067; rs29066
43 PROX1; rs7529073; rs79687284; rs2075423; rs340874; rs340839; rs7541039; rs6665764; rs3767844
44 PROX1; rs7529073; rs79687284; rs2075423; rs340874; rs340839; rs7541039; rs6665764; rs3767844
45 rs10752212; rs62209
46 rs10752212; rs62209
47 GNG2; rs8015138
48 GNG2; rs8015138
49 NEDD4L; rs17064520; rs2288774
50 NEDD4L; rs17064520; rs2288774
51 CDH26; FAM217B; PPP1R3D; SYCP2
52 CDH26; FAM217B; PPP1R3D; SYCP2
53 CDS1; WDFY3
54 CDS1; WDFY3
55 MBNL1; TMEM14E; rs185894411
56 MBNL1; TMEM14E; rs185894411
57 rs62152284; rs12615966
58 rs62152284; rs12615966
59 FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs755001161
60 FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs755001161
61 ARMC3; MSRB2
62 ARMC3; MSRB2
63 C2orf91; rs4305317; rs6740960; rs10211025
64 C2orf91; rs4305317; rs6740960; rs10211025
65 FYB; RICTOR; rs1060505056
66 FYB; RICTOR; rs1060505056
67 SGK1; rs1009840; rs4896030; rs9493873; rs1743966
68 SGK1; rs1009840; rs4896030; rs9493873; rs1743966
69 SRSF3; rs7771547
70 SRSF3; rs7771547
71 rs77693245; rs72912698
72 rs77693245; rs72912698
73 MEGF9; rs7044106
74 MEGF9; rs7044106
75 ASPN; CENPP; OGN; OMD
76 ASPN; CENPP; OGN; OMD
77 AIM2; rs855871; rs855873; rs855866; rs855867; rs2852720; rs2518564; rs2814764; rs1894043; rs2852727; rs1894044; rs2518569
78 AIM2; rs855871; rs855873; rs855866; rs855867; rs2852720; rs2518564; rs2814764; rs1894043; rs2852727; rs1894044; rs2518569
79 TCF7L2; rs17747324; rs34872471; rs7901695; rs4506565; rs7903146; rs4132670
80 TCF7L2; rs17747324; rs34872471; rs7901695; rs4506565; rs7903146; rs4132670
81 rs62152284; rs12615966
82 rs62152284; rs12615966
83 rs9608521; rs1894720
84 rs9608521; rs1894720
85 DSCAM; rs9980603
86 DSCAM; rs9980603
87 ADCY2; rs17231202; rs10512928; rs884964; rs12522444; rs11134242; rs4530734; rs12519539; rs34043481
88 ADCY2; rs17231202; rs10512928; rs884964; rs12522444; rs11134242; rs4530734; rs12519539; rs34043481
89 CREB5; rs56388170
90 CREB5; rs56388170
91 SH3BP4; rs6431360
92 SH3BP4; rs6431360
93 RAPGEF1; rs11243444; rs4740283
94 RAPGEF1; rs11243444; rs4740283
95 LDB2; rs12503223
96 LDB2; rs12503223
97 FRK; rs1933737; rs9488822; rs3822857; rs868943; rs6909746; rs1999930
98 FRK; rs1933737; rs9488822; rs3822857; rs868943; rs6909746; rs1999930
99 AMELX; ARHGAP6
100 AMELX; ARHGAP6
101 ACOX2; FAM107A; KCTD6; rs150832314; rs1057519329; rs11539086; rs13315591
102 ACOX2; FAM107A; KCTD6; rs150832314; rs1057519329; rs11539086; rs13315591
103 CDS1; WDFY3
104 CDS1; WDFY3
105 CD109; SLC17A5
106 CD109; SLC17A5
107 FRMD4A; rs1218412
108 FRMD4A; rs1218412
109 rs16914161
110 rs16914161
表3.a9
   探針 基因座
111 ORF12_12_99003375_99005607_99054128_99056579_FR ANKS1B; rs7960581
112 ORF12_12_99003375_99005607_99054128_99056579_FR ANKS1B; rs7960581
113 ORF12_6_157429181_157433330_157512149_157514915_FF TMEM242; ZDHHC14; rs181143083
114 ORF12_6_157429181_157433330_157512149_157514915_FF TMEM242; ZDHHC14; rs181143083
115 ORF12_7_147567494_147568852_147649122_147653562_FR CNTNAP2; rs201076428; rs6944808
116 ORF12_7_147567494_147568852_147649122_147653562_FR CNTNAP2; rs201076428; rs6944808
117 ORF120_21_34062321_34063413_34127427_34131035_RF MRPS6; SLC5A3; rs2834319
118 ORF120_21_34062321_34063413_34127427_34131035_RF MRPS6; SLC5A3; rs2834319
119 ORF121_10_121118423_121121606_121215466_121226127_RF rs1907240; rs2257129; rs3943077; rs35668226
120 ORF121_10_121118423_121121606_121215466_121226127_RF rs1907240; rs2257129; rs3943077; rs35668226
121 ORF122_5_42377041_42385919_42468953_42471569_FF GHR; rs6898743
122 ORF122_5_42377041_42385919_42468953_42471569_FF GHR; rs6898743
123 ORF123_5_159206195_159208288_159235024_159243123_RF RNF145; rs2901184; rs10515778; rs55801554
124 ORF123_5_159206195_159208288_159235024_159243123_RF RNF145; rs2901184; rs10515778; rs55801554
125 ORF125_15_96265261_96271086_96328347_96331473_RR NR2F2; rs2398180; rs587777373
126 ORF125_15_96265261_96271086_96328347_96331473_RR NR2F2; rs2398180; rs587777373
127 ORF125_6_158443203_158448925_158476552_158477736_FF TULP4; rs9456307
128 ORF125_6_158443203_158448925_158476552_158477736_FF TULP4; rs9456307
129 ORF126_13_99298431_99304510_99373432_99375888_RR GPR183; UBAC2; rs9557195; rs9513593
130 ORF126_13_99298431_99304510_99373432_99375888_RR GPR183; UBAC2; rs9557195; rs9513593
131 ORF127_11_120012095_120020785_120066945_120072959_FR PVRL1; TRIM29
132 ORF127_11_120012095_120020785_120066945_120072959_FR PVRL1; TRIM29
133 ORF128_14_74830356_74835394_74873740_74878249_RR DLST; PROX2; YLPM1
134 ORF128_14_74830356_74835394_74873740_74878249_RR DLST; PROX2; YLPM1
135 ORF13_10_121477867_121479994_121564423_121570750_RF FGFR2; rs749474548; rs1057519795; rs1057520029; rs1057520027; rs879253720; rs121918508; rs1057519047; rs1057519854; rs777169135; rs121918509; rs1057519796; rs751047267; rs121918506; rs1057519797; rs121913476; rs1057519045; rs1057519901; rs1057519798; rs1057519799; rs1057519800; rs121918507; rs1057520044; rs751731391; rs387906677; rs1057519900; rs387906678; rs121913478; rs1057520028; rs121913477; rs879253721; rs121918490; rs121918502; rs121918494; rs121918491; rs121918492; rs121918496; rs121918487; rs121918488; rs121918495; rs121918489; rs1057519044; rs1057519043; rs387906676; rs1057519042; rs121918493; rs121918510; rs121918504; rs1057519791; rs121913475; rs1057519040; rs374608214; rs121918500; rs121918499; rs1057519039; rs121918501; rs121918497; rs1057519038; rs776587763; rs1057519036; rs879253718; rs121918505; rs779326224; rs387907372; rs77543610; rs121918498; rs79184941; rs3135753; rs11199993; rs755001161; rs148514974; rs10510097; rs4752569
136 ORF13_10_121477867_121479994_121564423_121570750_RF FGFR2; rs749474548; rs1057519795; rs1057520029; rs1057520027; rs879253720; rs121918508; rs1057519047; rs1057519854; rs777169135; rs121918509; rs1057519796; rs751047267; rs121918506; rs1057519797; rs121913476; rs1057519045; rs1057519901; rs1057519798; rs1057519799; rs1057519800; rs121918507; rs1057520044; rs751731391; rs387906677; rs1057519900; rs387906678; rs121913478; rs1057520028; rs121913477; rs879253721; rs121918490; rs121918502; rs121918494; rs121918491; rs121918492; rs121918496; rs121918487; rs121918488; rs121918495; rs121918489; rs1057519044; rs1057519043; rs387906676; rs1057519042; rs121918493; rs121918510; rs121918504; rs1057519791; rs121913475; rs1057519040; rs374608214; rs121918500; rs121918499; rs1057519039; rs121918501; rs121918497; rs1057519038; rs776587763; rs1057519036; rs879253718; rs121918505; rs779326224; rs387907372; rs77543610; rs121918498; rs79184941; rs3135753; rs11199993; rs755001161; rs148514974; rs10510097; rs4752569
137 ORF13_13_23148292_23151659_23204130_23213800_RR SGCG; rs76916029; rs764468720; rs138880406; rs781760379; rs200502077; rs797045106; rs570169794
138 ORF13_13_23148292_23151659_23204130_23213800_RR SGCG; rs76916029; rs764468720; rs138880406; rs781760379; rs200502077; rs797045106; rs570169794
139 ORF13_13_45996676_46000524_46057524_46060260_RR CPB2; ZC3H13; rs1926447; rs779491029; rs3742264
140 ORF13_13_45996676_46000524_46057524_46060260_RR CPB2; ZC3H13; rs1926447; rs779491029; rs3742264
141 ORF13_15_96275929_96277834_96328347_96331473_RR NR2F2; rs2398180; rs587777373
142 ORF13_15_96275929_96277834_96328347_96331473_RR NR2F2; rs2398180; rs587777373
143 ORF13_2_65241569_65243972_65289753_65296291_FR ACTR2; SPRED2; rs62139085
144 ORF13_2_65241569_65243972_65289753_65296291_FR ACTR2; SPRED2; rs62139085
145 ORF13_2_79971437_79976448_80050108_80055044_RF CTNNA2; rs6738962; rs13427272
146 ORF13_2_79971437_79976448_80050108_80055044_RF CTNNA2; rs6738962; rs13427272
147 ORF13_6_23219349_23223439_23271280_23277154_RF rs7771911
148 ORF13_6_23219349_23223439_23271280_23277154_RF rs7771911
149 ORF13_7_155741321_155744332_155779388_155780808_FR RBM33; SHH
150 ORF13_7_155741321_155744332_155779388_155780808_FR RBM33; SHH
151 ORF131_20_8536736_8541378_8590421_8594259_FR PLCB1; rs4432538
152 ORF131_20_8536736_8541378_8590421_8594259_FR PLCB1; rs4432538
153 ORF132_5_173916958_173918697_173969421_173970862_RR C5orf47; CPEB4; rs10516107; rs6861681; rs17076724; rs17076726; rs56163845; rs72812846; rs72812861
154 ORF132_5_173916958_173918697_173969421_173970862_RR C5orf47; CPEB4; rs10516107; rs6861681; rs17076724; rs17076726; rs56163845; rs72812846; rs72812861
155 ORF132_7_117292584_117297912_117353457_117366529_RF ASZ1; WNT2; rs114167782; rs749398878; rs3779547
156 ORF132_7_117292584_117297912_117353457_117366529_RF ASZ1; WNT2; rs114167782; rs749398878; rs3779547
157 ORF133_4_151328386_151338975_151358698_151359731_RR FAM160A1; SH3D19
158 ORF133_4_151328386_151338975_151358698_151359731_RR FAM160A1; SH3D19
159 ORF134_6_82026159_82034690_82077947_82085585_RR IBTK; rs10806235
160 ORF134_6_82026159_82034690_82077947_82085585_RR IBTK; rs10806235
161 ORF138_10_104234446_104238473_104264982_104269909_RR CFAP43; GSTO1; GSTO2; rs11191972; rs4925
162 ORF138_10_104234446_104238473_104264982_104269909_RR CFAP43; GSTO1; GSTO2; rs11191972; rs4925
163 ORF138_2_77502067_77504306_77514867_77519288_FR LRRTM4; rs61354037
164 ORF138_2_77502067_77504306_77514867_77519288_FR LRRTM4; rs61354037
165 ORF14_1_76032659_76035831_76077590_76079532_RF ST6GALNAC3; rs12095069
166 ORF14_1_76032659_76035831_76077590_76079532_RF ST6GALNAC3; rs12095069
167 ORF14_1_8423193_8424500_8478289_8482650_FR RERE; rs301807; rs301797; rs301798; rs172531; rs34976449; rs301819; rs159963; rs142472947; rs4908760; rs301806
168 ORF14_1_8423193_8424500_8478289_8482650_FR RERE; rs301807; rs301797; rs301798; rs172531; rs34976449; rs301819; rs159963; rs142472947; rs4908760; rs301806
169 ORF14_10_97762614_97766905_97790822_97793778_RF SFRP5; ZFYVE27; rs7072751
170 ORF14_10_97762614_97766905_97790822_97793778_RF SFRP5; ZFYVE27; rs7072751
171 ORF14_12_75070822_75072825_75141366_75143140_FF CAPS2; KCNC2
172 ORF14_12_75070822_75072825_75141366_75143140_FF CAPS2; KCNC2
173 ORF14_13_51302963_51306635_51323631_51326485_RR FAM124A; SERPINE3
174 ORF14_13_51302963_51306635_51323631_51326485_RR FAM124A; SERPINE3
175 ORF14_15_77328486_77331349_77382463_77385598_RR HMG20A; PEAK1
176 ORF14_15_77328486_77331349_77382463_77385598_RR HMG20A; PEAK1
177 ORF14_19_56921649_56925569_56987150_56988841_FR USP29; ZIM2
178 ORF14_19_56921649_56925569_56987150_56988841_FR USP29; ZIM2
179 ORF14_3_105431137_105438494_105503436_105507339_FF ALCAM; rs13070790
180 ORF14_3_105431137_105438494_105503436_105507339_FF ALCAM; rs13070790
181 ORF14_3_16438382_16444965_16476728_16479586_FF RFTN1; rs3856834
182 ORF14_3_16438382_16444965_16476728_16479586_FF RFTN1; rs3856834
183 ORF14_4_125340607_125343598_125392915_125397466_RR FAT4; rs1039808
184 ORF14_4_125340607_125343598_125392915_125397466_RR FAT4; rs1039808
185 ORF14_6_168789036_168790083_168918636_168926703_RR rs196458; rs116146467
186 ORF14_6_168789036_168790083_168918636_168926703_RR rs196458; rs116146467
187 ORF14_8_109580000_109582610_109632260_109640195_RF EBAG9; SYBU
188 ORF14_8_109580000_109582610_109632260_109640195_RF EBAG9; SYBU
189 ORF14_8_28471461_28475878_28536205_28541536_FR FBXO16; FZD3; rs17059209
190 ORF14_8_28471461_28475878_28536205_28541536_FR FBXO16; FZD3; rs17059209
191 ORF14_X_111096546_111110500_111165610_111175893_FF PAK3; rs121434612; rs780775497; rs121434613
192 ORF14_X_111096546_111110500_111165610_111175893_FF PAK3; rs121434612; rs780775497; rs121434613
193 ORF140_2_38110623_38114294_38179203_38180978_FR ATL2; CYP1B1
194 ORF140_2_38110623_38114294_38179203_38180978_FR ATL2; CYP1B1
195 ORF141_6_115981175_115984851_116074475_116077750_FF FRK; NT5DC1; rs1933737; rs9488822; rs3822857; rs868943; rs6909746; rs1999930
196 ORF141_6_115981175_115984851_116074475_116077750_FF FRK; NT5DC1; rs1933737; rs9488822; rs3822857; rs868943; rs6909746; rs1999930
197 ORF142_2_38110623_38114294_38179203_38180978_FF ATL2; CYP1B1
198 ORF142_2_38110623_38114294_38179203_38180978_FF ATL2; CYP1B1
199 ORF142_8_22647922_22651917_22671292_22674484_FF BIN3; EGR3; rs2280104
200 ORF142_8_22647922_22651917_22671292_22674484_FF BIN3; EGR3; rs2280104
201 ORF144_11_133321952_133325802_133378245_133382756_FR OPCML; rs7104890; rs4379857
202 ORF144_11_133321952_133325802_133378245_133382756_FR OPCML; rs7104890; rs4379857
203 ORF144_13_32247490_32254361_32296396_32300347_RR FRY; ZAR1L; rs56404467; rs56084662
204 ORF144_13_32247490_32254361_32296396_32300347_RR FRY; ZAR1L; rs56404467; rs56084662
205 ORF147_2_102946170_102956566_102983000_102995309_FR TMEM182; rs12105421
206 ORF147_2_102946170_102956566_102983000_102995309_FR TMEM182; rs12105421
207 ORF148_3_65827279_65831993_65898255_65903690_RF MAGI1; rs145965284
208 ORF148_3_65827279_65831993_65898255_65903690_RF MAGI1; rs145965284
209 ORF149_14_68260022_68266399_68325745_68327713_RF RAD51B; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566; rs1570106
210 ORF149_14_68260022_68266399_68325745_68327713_RF RAD51B; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566; rs1570106
211 ORF15_1_13945271_13952984_14001723_14008533_FF rs7542939
212 ORF15_1_13945271_13952984_14001723_14008533_FF rs7542939
213 ORF15_10_121564423_121570750_121690817_121692131_FR FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs1219515; rs1696803; rs755001161
214 ORF15_10_121564423_121570750_121690817_121692131_FR FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs1219515; rs1696803; rs755001161
215 ORF15_10_25034559_25040591_25081322_25084214_RF ENKUR; THNSL1
216 ORF15_10_25034559_25040591_25081322_25084214_RF ENKUR; THNSL1
217 ORF15_10_76410191_76412075_76458091_76462498_FR C10orf11; rs11593840; rs10509373
218 ORF15_10_76410191_76412075_76458091_76462498_FR C10orf11; rs11593840; rs10509373
219 ORF15_12_10096371_10100557_10157054_10158072_RF CLEC1A; CLEC7A; OLR1; rs16910526; rs16910527; rs7309123; rs2078178; rs3901533
220 ORF15_12_10096371_10100557_10157054_10158072_RF CLEC1A; CLEC7A; OLR1; rs16910526; rs16910527; rs7309123; rs2078178; rs3901533
表3.b1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
111 110; NA 2; 1; NA 0.124006577; 0.042275815; NA
112 110; NA 2; 1; NA 0.124006577; 0.042275815; NA
113 98; 77; NA 1; 2; 1; 2; NA 0.080334308; 0.135364458; 0.14587104; 0.206032338; NA
114 98; 77; NA 1; 2; 1; 2; NA 0.080334308; 0.135364458; 0.14587104; 0.206032338; NA
115 53; NA 1; 1; NA 0.261255041; 0.238249082; NA
116 53; NA 1; 1; NA 0.261255041; 0.238249082; NA
117 7; 7; NA 1; 1; 1; 1; NA 0.215038813; 0.227740664; 0.215038813; 0.227740664; NA
118 7; 7; NA 1; 1; 1; 1; NA 0.215038813; 0.227740664; 0.215038813; 0.227740664; NA
119 NA NA NA
120 NA NA NA
121 16; NA 1; 2; NA 0.343724359; 0.116490918; NA
122 16; NA 1; 2; NA 0.343724359; 0.116490918; NA
123 6; NA 1; 1; NA 0.191789359; 0.203777963; NA
124 6; NA 1; 1; NA 0.191789359; 0.203777963; NA
125 62; NA 3; 3; NA 0.214894644; 0.223472567; NA
126 62; NA 3; 3; NA 0.214894644; 0.223472567; NA
127 65; NA 1; 1; NA 0.198659276; 0.174214187; NA
128 65; NA 1; 1; NA 0.198659276; 0.174214187; NA
129 49; 58; NA 1; 1; 1; 1; NA 0.283240383; 0.261686551; 0.234279681; 0.210195578; NA
130 49; 58; NA 1; 1; 1; 1; NA 0.283240383; 0.261686551; 0.234279681; 0.210195578; NA
131 30; 50 1; 1; 1; 1 0.36936157; 0.363021342; 0.277739605; 0.255769837
132 30; 50 1; 1; 1; 1 0.36936157; 0.363021342; 0.277739605; 0.255769837
133 22; 22; 16 1; 1; 1; 1; 1; 1 0.372324987; 0.375573766; 0.372324987; 0.375573766; 0.343724359; 0.353547066
134 22; 22; 16 1; 1; 1; 1; 1; 1 0.372324987; 0.375573766; 0.372324987; 0.375573766; 0.343724359; 0.353547066
135 190; NA 5; 4; NA 0.112399625; 0.054978865; NA
136 190; NA 5; 4; NA 0.112399625; 0.054978865; NA
137 5; NA 1; 1; NA 0.166301763; 0.177271291; NA
138 5; NA 1; 1; NA 0.166301763; 0.177271291; NA
139 7; 50; NA 1; 1; 3; 3; NA 0.215038813; 0.227740664; 0.179388457; 0.193973801; NA
140 7; 50; NA 1; 1; 3; 3; NA 0.215038813; 0.227740664; 0.179388457; 0.193973801; NA
141 62; NA 3; 3; NA 0.214894644; 0.223472567; NA
142 62; NA 3; 3; NA 0.214894644; 0.223472567; NA
143 59; 59; NA 1; 1; 1; 1; NA 0.229012733; 0.204801276; 0.229012733; 0.204801276; NA
144 59; 59; NA 1; 1; 1; 1; NA 0.229012733; 0.204801276; 0.229012733; 0.204801276; NA
145 40; NA 2; 3; NA 0.261899069; 0.150241062; NA
146 40; NA 2; 3; NA 0.261899069; 0.150241062; NA
147 NA NA NA
148 NA NA NA
149 34; 34 1; 1; 1; 1 0.357029649; 0.346365974; 0.357029649; 0.346365974
150 34; 34 1; 1; 1; 1 0.357029649; 0.346365974; 0.357029649; 0.346365974
151 15; NA 1; 1; NA 0.335307856; 0.346011739; NA
152 15; NA 1; 1; NA 0.335307856; 0.346011739; NA
153 50; 120; NA 1; 1; 1; 1; NA 0.277739605; 0.255769837; 0.040862114; 0.029934241; NA
154 50; 120; NA 1; 1; 1; 1; NA 0.277739605; 0.255769837; 0.040862114; 0.029934241; NA
155 23; 23; NA 2; 2; 2; 2; NA 0.166907425; 0.181828486; 0.166907425; 0.181828486; NA
156 23; 23; NA 2; 2; 2; 2; NA 0.166907425; 0.181828486; 0.166907425; 0.181828486; NA
157 9; 14 1; 1; 1; 1 0.255358235; 0.268692312; 0.325643034; 0.337131196
158 9; 14 1; 1; 1; 1 0.255358235; 0.268692312; 0.325643034; 0.337131196
159 15; NA 2; 1; NA 0.095167761; 0.346011739; NA
160 15; NA 2; 1; NA 0.095167761; 0.346011739; NA
161 36; 36; 26; NA 1; 1; 1; 1; 1; 1; NA 0.349116343; 0.336492635; 0.349116343; 0.336492635; 0.375314357; 0.373699919; NA
162 36; 36; 26; NA 1; 1; 1; 1; 1; 1; NA 0.349116343; 0.336492635; 0.349116343; 0.336492635; 0.375314357; 0.373699919; NA
163 9; NA 3; 2; NA 0.00391071; 0.047199169; NA
164 9; NA 3; 2; NA 0.00391071; 0.047199169; NA
165 45; NA 5; 5; NA 0.022343156; 0.028833151; NA
166 45; NA 5; 5; NA 0.022343156; 0.028833151; NA
167 16; NA 2; 1; NA 0.104530159; 0.353547066; NA
168 16; NA 2; 1; NA 0.104530159; 0.353547066; NA
169 26; 28; NA 1; 1; 1; 1; NA 0.375314357; 0.373699919; 0.373281001; 0.369266824; NA
170 26; 28; NA 1; 1; 1; 1; NA 0.375314357; 0.373699919; 0.373281001; 0.369266824; NA
171 13; 13 4; 4; 4; 4 0.001148684; 0.001517434; 0.001148684; 0.001517434
172 13; 13 4; 4; 4; 4 0.001148684; 0.001517434; 0.001148684; 0.001517434
173 40; 43 2; 2; 2; 2 0.261899069; 0.269983451; 0.269116178; 0.27473038
174 40; 43 2; 2; 2; 2 0.261899069; 0.269983451; 0.269116178; 0.27473038
175 38; 9 1; 1; 1; 1 0.340322106; 0.325888812; 0.255358235; 0.268692312
176 38; 9 1; 1; 1; 1 0.340322106; 0.325888812; 0.255358235; 0.268692312
177 24; 28 1; 1; 1; 1 0.375122937; 0.375945017; 0.373281001; 0.369266824
178 24; 28 1; 1; 1; 1 0.375122937; 0.375945017; 0.373281001; 0.369266824
179 5; NA 1; 1; NA 0.166301763; 0.177271291; NA
180 5; NA 1; 1; NA 0.166301763; 0.177271291; NA
181 55; NA 2; 3; NA 0.274632664; 0.209439509; NA
182 55; NA 2; 3; NA 0.274632664; 0.209439509; NA
183 19; NA 3; 4; NA 0.030348034; 0.006361707; NA
184 19; NA 3; 4; NA 0.030348034; 0.006361707; NA
185 NA NA NA
186 NA NA NA
187 4; 4 1; 1; 1; 1 0.138432982; 0.14804367; 0.138432982; 0.14804367
188 4; 4 1; 1; 1; 1 0.138432982; 0.14804367; 0.138432982; 0.14804367
189 63; 57; NA 3; 3; 3; 3; NA 0.216848517; 0.224771745; 0.202795213; 0.214348844; NA
190 63; 57; NA 3; 3; 3; 3; NA 0.216848517; 0.224771745; 0.202795213; 0.214348844; NA
191 7; NA 1; 1; NA 0.215038813; 0.227740664; NA
192 7; NA 1; 1; NA 0.215038813; 0.227740664; NA
193 23; 34 4; 3; 4; 3 0.009574125; 0.055866229; 0.0324282; 0.117734198
194 23; 34 4; 3; 4; 3 0.009574125; 0.055866229; 0.0324282; 0.117734198
195 28; 28; NA 3; 2; 2; 1; NA 0.071800115; 0.219149094; 0.204457601; 0.369266824; NA
196 28; 28; NA 3; 2; 2; 1; NA 0.071800115; 0.219149094; 0.204457601; 0.369266824; NA
197 23; 34 4; 3; 4; 3 0.009574125; 0.055866229; 0.0324282; 0.117734198
198 23; 34 4; 3; 4; 3 0.009574125; 0.055866229; 0.0324282; 0.117734198
199 20; 57; NA 1; 1; 1; 1; NA 0.366490901; 0.372098641; 0.239596043; 0.215667339; NA
200 20; 57; NA 1; 1; 1; 1; NA 0.366490901; 0.372098641; 0.239596043; 0.215667339; NA
201 14; NA 1; 1; NA 0.325643034; 0.337131196; NA
202 14; NA 1; 1; NA 0.325643034; 0.337131196; NA
203 12; 12; NA 1; 1; 1; 1; NA 0.302214299; 0.314913912; 0.302214299; 0.314913912; NA
204 12; 12; NA 1; 1; 1; 1; NA 0.302214299; 0.314913912; 0.302214299; 0.314913912; NA
205 27; NA 2; 3; NA 0.197546356; 0.077717327; NA
206 27; NA 2; 3; NA 0.197546356; 0.077717327; NA
207 55; NA 5; 5; NA 0.042810093; 0.05348201; NA
208 55; NA 5; 5; NA 0.042810093; 0.05348201; NA
209 17; NA 3; 2; NA 0.023054538; 0.126473611; NA
210 17; NA 3; 2; NA 0.023054538; 0.126473611; NA
211 NA NA NA
212 NA NA NA
213 190; NA 5; 4; NA 0.112399625; 0.054978865; NA
214 190; NA 5; 4; NA 0.112399625; 0.054978865; NA
215 43; 17 1; 1; 1; 1 0.315614698; 0.297350686; 0.350975055; 0.359834557
216 43; 17 1; 1; 1; 1 0.315614698; 0.297350686; 0.350975055; 0.359834557
217 76; NA 4; 4; NA 0.169506823; 0.182516854; NA
218 76; NA 4; 4; NA 0.169506823; 0.182516854; NA
219 44; 68; 79; NA 2; 2; 2; 2; 2; 3; NA 0.270943694; 0.275697963; 0.251156755; 0.236353672; 0.219227; 0.224909805; NA
220 44; 68; 79; NA 2; 2; 2; 2; 2; 3; NA 0.270943694; 0.275697963; 0.251156755; 0.236353672; 0.219227; 0.224909805; NA
表3.b2
   FDR_HyperG Percent_Sig logFC AveExpr
111 0.375519541; 0.376115439; NA 1.82; 0.91; NA -0.777510613 -0.777510613
112 0.375519541; 0.376115439; NA 1.82; 0.91; NA -0.685826949 -0.685826949
113 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.02; 2.04; 1.3; 2.6; NA -0.852472454 -0.852472454
114 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.02; 2.04; 1.3; 2.6; NA -0.682585961 -0.682585961
115 0.375519541; 0.376115439; NA 1.89; 1.89; NA -1.389617965 -1.389617965
116 0.375519541; 0.376115439; NA 1.89; 1.89; NA -1.204568555 -1.204568555
117 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 14.29; 14.29; 14.29; 14.29; NA -0.883824041 -0.883824041
118 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 14.29; 14.29; 14.29; 14.29; NA -0.788321151 -0.788321151
119 NA NA -0.811021207 -0.811021207
120 NA NA -0.737688212 -0.737688212
121 0.375519541; 0.376115439; NA 6.25; 12.5; NA -1.087081052 -1.087081052
122 0.375519541; 0.376115439; NA 6.25; 12.5; NA -0.983682494 -0.983682494
123 0.375519541; 0.376115439; NA 16.67; 16.67; NA -0.927138124 -0.927138124
124 0.375519541; 0.376115439; NA 16.67; 16.67; NA -0.77161289 -0.77161289
125 0.375519541; 0.376115439; NA 4.84; 4.84; NA -0.767302384 -0.767302384
126 0.375519541; 0.376115439; NA 4.84; 4.84; NA -0.699515795 -0.699515795
127 0.375519541; 0.376115439; NA 1.54; 1.54; NA -1.110094335 -1.110094335
128 0.375519541; 0.376115439; NA 1.54; 1.54; NA -0.994718551 -0.994718551
129 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.04; 2.04; 1.72; 1.72; NA -1.013993605 -1.013993605
130 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.04; 2.04; 1.72; 1.72; NA -1.006858381 -1.006858381
131 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.33; 3.33; 2; 2 -1.047126655 -1.047126655
132 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.33; 3.33; 2; 2 -0.99558333 -0.99558333
133 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 4.55; 4.55; 6.25; 6.25 -1.210660143 -1.210660143
134 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 4.55; 4.55; 6.25; 6.25 -0.671308166 -0.671308166
135 0.375519541; 0.376115439; NA 2.63; 2.11; NA -1.140580782 -1.140580782
136 0.375519541; 0.376115439; NA 2.63; 2.11; NA -0.98447572 -0.98447572
137 0.375519541; 0.376115439; NA 20; 20; NA -0.925553319 -0.925553319
138 0.375519541; 0.376115439; NA 20; 20; NA -0.748812856 -0.748812856
139 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 14.29; 14.29; 6; 6; NA -0.886153821 -0.886153821
140 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 14.29; 14.29; 6; 6; NA -0.825853554 -0.825853554
141 0.375519541; 0.376115439; NA 4.84; 4.84; NA -1.022291185 -1.022291185
142 0.375519541; 0.376115439; NA 4.84; 4.84; NA -0.971200444 -0.971200444
143 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.69; 1.69; 1.69; 1.69; NA -1.07634228 -1.07634228
144 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.69; 1.69; 1.69; 1.69; NA -0.949556179 -0.949556179
145 0.375519541; 0.376115439; NA 5; 7.5; NA -0.873348319 -0.873348319
146 0.375519541; 0.376115439; NA 5; 7.5; NA -0.775572344 -0.775572344
147 NA NA -0.805004033 -0.805004033
148 NA NA -0.674883638 -0.674883638
149 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.94; 2.94; 2.94; 2.94 -0.786545722 -0.786545722
150 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.94; 2.94; 2.94; 2.94 -0.624964577 -0.624964577
151 0.375519541; 0.376115439; NA 6.67; 6.67; NA -0.915929727 -0.915929727
152 0.375519541; 0.376115439; NA 6.67; 6.67; NA -0.885925031 -0.885925031
153 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2; 2; 0.83; 0.83; NA -1.112146797 -1.112146797
154 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2; 2; 0.83; 0.83; NA -1.081744184 -1.081744184
155 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 8.7; 8.7; 8.7; 8.7; NA -1.227274379 -1.227274379
156 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 8.7; 8.7; 8.7; 8.7; NA -1.032857203 -1.032857203
157 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 11.11; 7.14; 7.14 -1.365554559 -1.365554559
158 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 11.11; 7.14; 7.14 -1.205008284 -1.205008284
159 0.375519541; 0.376115439; NA 13.33; 6.67; NA -0.850842245 -0.850842245
160 0.375519541; 0.376115439; NA 13.33; 6.67; NA -0.714977183 -0.714977183
161 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.78; 2.78; 2.78; 2.78; 3.85; 3.85; NA -1.450478131 -1.450478131
162 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.78; 2.78; 2.78; 2.78; 3.85; 3.85; NA -1.419835202 -1.419835202
163 0.185936467; 0.376115439; NA 33.33; 22.22; NA -1.23642913 -1.23642913
164 0.185936467; 0.376115439; NA 33.33; 22.22; NA -0.989238415 -0.989238415
165 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.899188624 -0.899188624
166 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.800106474 -0.800106474
167 0.375519541; 0.376115439; NA 12.5; 6.25; NA -0.963761492 -0.963761492
168 0.375519541; 0.376115439; NA 12.5; 6.25; NA -0.735002844 -0.735002844
169 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 3.85; 3.85; 3.57; 3.57; NA -1.016353323 -1.016353323
170 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 3.85; 3.85; 3.57; 3.57; NA -0.803235024 -0.803235024
171 0.069549998; 0.082088441; 0.069549998; 0.082088441 30.77; 30.77; 30.77; 30.77 -1.067563562 -1.067563562
172 0.069549998; 0.082088441; 0.069549998; 0.082088441 30.77; 30.77; 30.77; 30.77 -0.812353607 -0.812353607
173 0.375519541; 0.376115439; 0.375519541; 0.376115439 5; 5; 4.65; 4.65 -0.884025289 -0.884025289
174 0.375519541; 0.376115439; 0.375519541; 0.376115439 5; 5; 4.65; 4.65 -0.825481583 -0.825481583
175 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.63; 2.63; 11.11; 11.11 -0.967126149 -0.967126149
176 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.63; 2.63; 11.11; 11.11 -0.956368249 -0.956368249
177 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.17; 4.17; 3.57; 3.57 -1.203240678 -1.203240678
178 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.17; 4.17; 3.57; 3.57 -1.174006458 -1.174006458
179 0.375519541; 0.376115439; NA 20; 20; NA -0.792368549 -0.792368549
180 0.375519541; 0.376115439; NA 20; 20; NA -0.778935979 -0.778935979
181 0.375519541; 0.376115439; NA 3.64; 5.45; NA -1.148262216 -1.148262216
182 0.375519541; 0.376115439; NA 3.64; 5.45; NA -1.10801826 -1.10801826
183 0.375519541; 0.217379602; NA 15.79; 21.05; NA -1.414344323 -1.414344323
184 0.375519541; 0.217379602; NA 15.79; 21.05; NA -1.36499136 -1.36499136
185 NA NA -0.855173127 -0.855173127
186 NA NA -0.801464774 -0.801464774
187 0.375519541; 0.376115439; 0.375519541; 0.376115439 25; 25; 25; 25 -0.734170577 -0.734170577
188 0.375519541; 0.376115439; 0.375519541; 0.376115439 25; 25; 25; 25 -0.733715768 -0.733715768
189 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4.76; 4.76; 5.26; 5.26; NA -1.365740534 -1.365740534
190 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4.76; 4.76; 5.26; 5.26; NA -1.301686755 -1.301686755
191 0.375519541; 0.376115439; NA 14.29; 14.29; NA -1.016684978 -1.016684978
192 0.375519541; 0.376115439; NA 14.29; 14.29; NA -0.962834673 -0.962834673
193 0.357661967; 0.376115439; 0.375519541; 0.376115439 17.39; 13.04; 11.76; 8.82 -1.103935035 -1.103935035
194 0.357661967; 0.376115439; 0.375519541; 0.376115439 17.39; 13.04; 11.76; 8.82 -0.986266284 -0.986266284
195 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 10.71; 7.14; 7.14; 3.57; NA -0.991528799 -0.991528799
196 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 10.71; 7.14; 7.14; 3.57; NA -0.972344962 -0.972344962
197 0.357661967; 0.376115439; 0.375519541; 0.376115439 17.39; 13.04; 11.76; 8.82 -1.061516657 -1.061516657
198 0.357661967; 0.376115439; 0.375519541; 0.376115439 17.39; 13.04; 11.76; 8.82 -0.928465595 -0.928465595
199 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 5; 5; 1.75; 1.75; NA -1.376546241 -1.376546241
200 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 5; 5; 1.75; 1.75; NA -1.257571903 -1.257571903
201 0.375519541; 0.376115439; NA 7.14; 7.14; NA -0.876775257 -0.876775257
202 0.375519541; 0.376115439; NA 7.14; 7.14; NA -0.689672422 -0.689672422
203 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 8.33; 8.33; 8.33; 8.33; NA -0.925255622 -0.925255622
204 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 8.33; 8.33; 8.33; 8.33; NA -0.824269098 -0.824269098
205 0.375519541; 0.376115439; NA 7.41; 11.11; NA -1.022231252 -1.022231252
206 0.375519541; 0.376115439; NA 7.41; 11.11; NA -0.843090271 -0.843090271
207 0.375519541; 0.376115439; NA 9.09; 9.09; NA -0.97363056 -0.97363056
208 0.375519541; 0.376115439; NA 9.09; 9.09; NA -0.873957515 -0.873957515
209 0.375519541; 0.376115439; NA 17.65; 11.76; NA -1.04545911 -1.04545911
210 0.375519541; 0.376115439; NA 17.65; 11.76; NA -0.824222551 -0.824222551
211 NA NA -0.977373447 -0.977373447
212 NA NA -0.842420208 -0.842420208
213 0.375519541; 0.376115439; NA 2.63; 2.11; NA -0.941968114 -0.941968114
214 0.375519541; 0.376115439; NA 2.63; 2.11; NA -0.862034178 -0.862034178
215 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.33; 2.33; 5.88; 5.88 -1.086078797 -1.086078797
216 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.33; 2.33; 5.88; 5.88 -0.841320836 -0.841320836
217 0.375519541; 0.376115439; NA 5.26; 5.26; NA -0.834126422 -0.834126422
218 0.375519541; 0.376115439; NA 5.26; 5.26; NA -0.728967849 -0.728967849
219 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4.55; 4.55; 2.94; 2.94; 2.53; 3.8; NA -0.835114867 -0.835114867
220 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4.55; 4.55; 2.94; 2.94; 2.53; 3.8; NA -0.72611581 -0.72611581
表3.b3
   t P值 adj.P.Val B FC FC_1 LS
111 -14.36115991 0.00000000651 0.00000232 11.04469924 0.583372541 -1.714170498 -1
112 -9.329465798 0.000000786 0.0000639 6.297164838 0.621649397 -1.608623777 -1
113 -8.14278595 0.00000317 0.0000822 4.822145964 0.553834774 -1.805592654 -1
114 -5.091722152 0.000269874 0.002916131 0.323101255 0.623047491 -1.605014088 -1
115 -7.511428379 0.00000719 0.000139588 3.977752946 0.381665857 -2.620092898 -1
116 -7.717348519 0.0000056 0.000218549 4.300752547 0.433899084 -2.304683364 -1
117 -8.994540631 0.00000112 0.0000431 5.885498394 0.541929076 -1.845259913 -1
118 -7.486625246 0.0000076 0.000264198 3.989176087 0.579017497 -1.727063527 -1
119 -5.953638695 0.0000672 0.000626595 1.668249934 0.569978258 -1.754452887 -1
120 -5.543469094 0.000129579 0.001748926 1.076513756 0.599699547 -1.667501677 -1
121 -10.48148624 0.000000218 0.0000158 7.556007791 0.470712787 -2.124437722 -1
122 -11.23480801 0.000000106 0.0000191 8.304307297 0.505687319 -1.977506579 -1
123 -8.610688483 0.00000182 0.000108468 5.444458359 0.525900537 -1.901500244 -1
124 -13.06779282 0.0000000189 0.00000399 9.99985585 0.585762244 -1.70717729 -1
125 -9.053539931 0.00000105 0.0000412 5.956116526 0.58751501 -1.702084173 -1
126 -9.164417643 0.000000949 0.0000718 6.106390455 0.615778843 -1.623959659 -1
127 -11.73476447 0.000000063 0.00000752 8.805528531 0.463263738 -2.158597614 -1
128 -14.72041303 0.00000000515 0.000004 11.22840766 0.501833765 -1.992691742 -1
129 -9.558295537 0.000000608 0.0000547 6.556892291 0.495173631 -2.019493643 -1
130 -9.075013641 0.00000102 0.0000406 5.981724979 0.497628707 -2.00953037 -1
131 -8.355022506 0.00000243 0.0000698 5.094994747 0.483931027 -2.066410179 -1
132 -12.5435734 0.0000000312 0.00000985 9.501483884 0.501533047 -1.993886557 -1
133 -7.779408145 0.00000505 0.000111358 4.342263898 0.432070865 -2.314435156 -1
134 -4.805075445 0.000436255 0.004079528 -0.16923243 0.627937046 -1.592516329 -1
135 -12.40851702 0.0000000338 0.00000546 9.425222726 0.453576946 -2.204697593 -1
136 -13.33417997 0.0000000157 0.00000701 10.16382252 0.505409357 -1.978594155 -1
137 -10.45242145 0.000000225 0.000016 7.525413378 0.526478558 -1.899412587 -1
138 -7.51191533 0.00000735 0.000258714 4.023665668 0.595093038 -1.68040951 -1
139 -8.26991208 0.0000027 0.0000744 4.986224241 0.541054631 -1.848242195 -1
140 -9.859082055 0.000000436 0.0000447 6.890097661 0.564148332 -1.772583457 -1
141 -10.07315497 0.000000335 0.0000202 7.118997831 0.492333842 -2.031142114 -1
142 -18.74359611 0.000000000322 0.00000121 13.75629268 0.510081455 -1.960471194 -1
143 -10.12569182 0.000000327 0.0000378 7.17791162 0.474229633 -2.108683073 -1
144 -6.572087681 0.0000266 0.00033238 2.625216777 0.517791727 -1.931278441 -1
145 -6.81988753 0.000019 0.000482369 3.049127096 0.545878462 -1.831909608 -1
146 -4.815162336 0.000424325 0.002359018 -0.233217999 0.584156833 -1.711869047 -1
147 -9.385119881 0.000000716 0.0000327 6.346029874 0.57236048 -1.747150676 -1
148 -9.004759632 0.00000114 0.0000807 5.919040127 0.626382739 -1.596468003 -1
149 -8.671656636 0.00000165 0.0000548 5.492202876 0.579730494 -1.724939452 -1
150 -7.487430405 0.00000759 0.000264039 3.990275418 0.648435699 -1.542172959 -1
151 -7.258163966 0.0000103 0.000322406 3.673793273 0.530002207 -1.886784595 -1
152 -6.431068475 0.0000327 0.000381029 2.411745899 0.541140442 -1.847949115 -1
153 -18.82495171 0.000000000306 0.00000118 13.80026651 0.462605141 -2.161670747 -1
154 -16.80621079 0.00000000107 0.000000994 12.7653672 0.472457288 -2.116593447 -1
155 -7.739344153 0.00000532 0.000115212 4.288348991 0.42712363 -2.34124251 -1
156 -6.391893966 0.0000353 0.000723569 2.413482092 0.488741256 -2.04607241 -1
157 -13.42644648 0.0000000139 0.0000034 10.30011908 0.388085232 -2.57675355 -1
158 -7.042293387 0.0000139 0.000391456 3.369385239 0.433766853 -2.305385931 -1
159 -7.277271387 0.00000986 0.000172376 3.651653273 0.554460947 -1.803553532 -1
160 -16.3013331 0.00000000161 0.00000232 12.3113832 0.609214767 -1.641457257 -1
161 -19.37444065 0.000000000219 0.00000103 14.09090854 0.365900139 -2.732986116 -1
162 -17.42774343 0.000000000707 0.000000818 13.15722335 0.373755004 -2.675549466 -1
163 -7.835349078 0.00000469 0.000106363 4.417206862 0.42442186 -2.356146312 -1
164 -6.398620016 0.0000349 0.000719449 2.423670925 0.503743626 -1.985136779 -1
165 -9.978256334 0.000000371 0.0000215 7.015173256 0.5361882 -1.865016797 -1
166 -12.04374371 0.0000000491 0.0000125 9.059857955 0.574306791 -1.741229628 -1
167 -7.432057605 0.000008 0.000149619 3.86801945 0.512718375 -1.950388456 -1
168 -6.835435792 0.0000186 0.00047492 3.07173748 0.60081684 -1.664400751 -1
169 -7.33146989 0.00000916 0.000164215 3.727772169 0.494364371 -2.022799494 -1
170 -7.94470137 0.00000417 0.000181823 4.60112036 0.57306273 -1.745009661 -1
171 -8.864593817 0.00000131 0.0000472 5.72861235 0.477124091 -2.095890815 -1
172 -5.516165861 0.000135344 0.001801338 1.031785152 0.569452098 -1.756073959 -1
173 -7.28062139 0.00001 0.000316867 3.705101749 0.541853485 -1.845517336 -1
174 -8.609406076 0.00000178 0.0000574 5.415026424 0.564293805 -1.77212649 -1
175 -13.18263612 0.0000000179 0.00000756 10.04015243 0.511524005 -1.954942465 -1
176 -9.29108093 0.000000797 0.0000348 6.236634019 0.515352599 -1.94041905 -1
177 -7.680068446 0.00000575 0.000121209 4.208208069 0.434298634 -2.302563077 -1
178 -8.048087702 0.00000366 0.000167842 4.735566313 0.443188866 -2.256374375 -1
179 -11.73019986 0.0000000657 0.0000145 8.77318977 0.577395373 -1.731915508 -1
180 -8.108654172 0.00000331 0.0000844 4.777761087 0.58279646 -1.715864916 -1
181 -10.6386507 0.000000192 0.0000276 7.712625118 0.451168355 -2.216467511 -1
182 -12.8435874 0.000000023 0.00000441 9.807808076 0.463930866 -2.155493571 -1
183 -8.305275046 0.00000265 0.000136934 5.064329258 0.375180221 -2.665385713 -1
184 -11.46034961 0.0000000818 0.00000877 8.543116287 0.388236763 -2.575747833 -1
185 -7.722119441 0.00000544 0.000116957 4.265107035 0.552798986 -1.808975823 -1
186 -5.626197218 0.000113641 0.001593899 1.211396633 0.573766334 -1.742869771 -1
187 -6.742036766 0.0000208 0.000283309 2.8788032 0.601163542 -1.663440862 -1
188 -9.512868638 0.000000639 0.0000563 6.505766321 0.601353088 -1.662916546 -1
189 -10.78142068 0.00000016 0.0000131 7.867278572 0.388035208 -2.577085735 -1
190 -11.18705796 0.000000111 0.0000197 8.258043755 0.405651645 -2.465169343 -1
191 -12.11903577 0.000000044 0.00000624 9.163137768 0.494250737 -2.02326456 -1
192 -7.926701227 0.00000427 0.000184673 4.57757664 0.513047863 -1.949135886 -1
193 -10.30906949 0.00000027 0.0000338 7.371891113 0.465245779 -2.149401555 -1
194 -9.923834321 0.000000394 0.0000223 6.955238775 0.50478247 -1.981051361 -1
195 -10.10568277 0.000000335 0.0000381 7.15655134 0.502944531 -1.988290833 -1
196 -8.142855314 0.00000317 0.0000822 4.822236021 0.509676958 -1.962027091 -1
197 -9.254589617 0.000000831 0.0000357 6.193932519 0.479128104 -2.087124493 -1
198 -7.604991107 0.00000649 0.000238631 4.149881318 0.525416862 -1.903250681 -1
199 -10.89159511 0.000000143 0.0000122 7.979616717 0.385139703 -2.596460434 -1
200 -10.26639227 0.000000282 0.0000344 7.327031514 0.41824729 -2.390930017 -1
201 -7.266061704 0.00001 0.000174155 3.635861464 0.544583336 -1.836266249 -1
202 -6.713994662 0.0000221 0.000532452 2.894245117 0.61999461 -1.612917248 -1
203 -7.887395661 0.00000439 0.000101601 4.486580906 0.526587207 -1.899020687 -1
204 -8.280045772 0.00000273 0.000139801 5.032433217 0.564768254 -1.770637766 -1
205 -15.53259283 0.00000000266 0.00000146 11.90706034 0.492354295 -2.031057737 -1
206 -10.22567586 0.000000295 0.0000355 7.284072518 0.557448228 -1.793888561 -1
207 -6.687733525 0.0000229 0.000544781 2.855593332 0.509222983 -1.963776249 -1
208 -7.339941465 0.00000905 0.000162777 3.739635067 0.545648007 -1.83268332 -1
209 -8.181096093 0.00000309 0.000151018 4.906595586 0.484490704 -2.06402309 -1
210 -6.462041292 0.0000313 0.00036911 2.458870021 0.564786476 -1.770580639 -1
211 -8.253960116 0.00000275 0.0000752 4.965741833 0.507903582 -1.96887763 -1
212 -11.78427903 0.0000000624 0.0000139 8.823179824 0.557707196 -1.79305558 -1
213 -11.4918894 0.0000000824 0.0000165 8.550125208 0.520522303 -1.921147267 -1
214 -8.485740357 0.00000207 0.0000631 5.260387487 0.550176271 -1.817599292 -1
215 -12.70568263 0.0000000259 0.00000477 9.68797636 0.471039909 -2.122962367 -1
216 -9.726417232 0.000000504 0.000049 6.744262912 0.558132346 -1.791689743 -1
217 -13.56132442 0.000000013 0.00000631 10.34638001 0.560922585 -1.782777208 -1
218 -5.481507636 0.000141134 0.001057191 0.90132511 0.603335405 -1.657452871 -1
219 -6.72055369 0.0000219 0.000529538 2.903883844 0.560538407 -1.783999074 -1
220 -8.251268787 0.00000276 0.0000753 4.962283155 0.604529308 -1.654179518 -1
表3.b4
      探針序列 探針位置
偵測到之環 60 mer Chr
111 sAD CCTCTTTTTACATGTCTCCTTTTCCCTCTCGAAGTGACTCACTTCTAAAACTTGGGCTGC 12
112 mAD CCTCTTTTTACATGTCTCCTTTTCCCTCTCGAAGTGACTCACTTCTAAAACTTGGGCTGC 12
113 sAD CAAATATCATTATGTATCTTTTCTGATATCGAGAACCAGATGTTATACTTTGGAGACTCC 6
114 mAD CAAATATCATTATGTATCTTTTCTGATATCGAGAACCAGATGTTATACTTTGGAGACTCC 6
115 sAD GATTAATAGTAACAATAGTAAATAATGCTCGAGTTGTACTAAAAGGGTACTGCTAGTGCC 7
116 mAD GATTAATAGTAACAATAGTAAATAATGCTCGAGTTGTACTAAAAGGGTACTGCTAGTGCC 7
117 sAD CATGTCACTTGTGCCATGTAGCACATGGTCGATACTTATCCACCATGAAGCTTAAGAGAA 21
118 mAD CATGTCACTTGTGCCATGTAGCACATGGTCGATACTTATCCACCATGAAGCTTAAGAGAA 21
119 sAD TTGGAACTACTTCTTAGGACCTTAAATTTCGAAACATGGTTGAAAGCTTTCTGACAGAGC 10
120 mAD TTGGAACTACTTCTTAGGACCTTAAATTTCGAAACATGGTTGAAAGCTTTCTGACAGAGC 10
121 sAD ATGCTAAATTATGTAAAATGGAATATGTTCGAACTAGGCAGTCTGACTTTTCTATGTGTG 5
122 mAD ATGCTAAATTATGTAAAATGGAATATGTTCGAACTAGGCAGTCTGACTTTTCTATGTGTG 5
123 mAD ATCATTTTTTTTTCAAGCTTAGCCTCATTCGAGACTGAAATGTTTTTAACAAGGACTTTG 5
124 sAD ATCATTTTTTTTTCAAGCTTAGCCTCATTCGAGACTGAAATGTTTTTAACAAGGACTTTG 5
125 sAD TTCAGTCATTAATGAGTTAATAAAAATCTCGATATTGTTCCTTCCCATGTTTGTAAAAGG 15
126 mAD TTCAGTCATTAATGAGTTAATAAAAATCTCGATATTGTTCCTTCCCATGTTTGTAAAAGG 15
127 sAD TAAATGTATATTGTCTTCCTAAAACAAATCGAACGTTAGTTCTCAATTCTTTGAGGAATT 6
128 mAD TAAATGTATATTGTCTTCCTAAAACAAATCGAACGTTAGTTCTCAATTCTTTGAGGAATT 6
129 mAD GTACTTTCATCATTTAGTTCTAAGCATTTCGATTCATGTCTTTCTTTCCTTTAGCTGACA 13
130 sAD GTACTTTCATCATTTAGTTCTAAGCATTTCGATTCATGTCTTTCTTTCCTTTAGCTGACA 13
131 sAD TAAAATAGGTCTATAAATTATACTTCAGTCGAATTTAATCTGCGTCTGATATGCTGGCAG 11
132 mAD TAAAATAGGTCTATAAATTATACTTCAGTCGAATTTAATCTGCGTCTGATATGCTGGCAG 11
133 sAD TTTTAAAGGATATACACATCTATCACTATCGAAAAGGCCAAGCTACTTCTAGAACAGTAT 14
134 mAD TTTTAAAGGATATACACATCTATCACTATCGAAAAGGCCAAGCTACTTCTAGAACAGTAT 14
135 sAD ATGTATTTTTCACAATATGAATTAAAAGTCGAACATTTGTCCAAGTTTTCTTTTGGAAAA 10
136 mAD ATGTATTTTTCACAATATGAATTAAAAGTCGAACATTTGTCCAAGTTTTCTTTTGGAAAA 10
137 sAD TTAAAGCAAGTTATGTAGGTAATTAATTTCGAAATAGTGGGAATATTGTAATAGTCTTTA 13
138 mAD TTAAAGCAAGTTATGTAGGTAATTAATTTCGAAATAGTGGGAATATTGTAATAGTCTTTA 13
139 sAD GGTCATTATTAAGTAAAATAAGGGTTACTCGAAGCCTAGCTACAATCCTTCAAGAATCCT 13
140 mAD GGTCATTATTAAGTAAAATAAGGGTTACTCGAAGCCTAGCTACAATCCTTCAAGAATCCT 13
141 sAD AAAGATCGTGTGGAAGAAATTTCTCTGTTCGATATTGTTCCTTCCCATGTTTGTAAAAGG 15
142 mAD AAAGATCGTGTGGAAGAAATTTCTCTGTTCGATATTGTTCCTTCCCATGTTTGTAAAAGG 15
143 mAD ACTTAGTAGGATTTTTTTATTAAAATTTTCGAGGAACCACAGTGATGCTGTATTTTGTAA 2
144 sAD ACTTAGTAGGATTTTTTTATTAAAATTTTCGAGGAACCACAGTGATGCTGTATTTTGTAA 2
145 mAD CTTTTGACATTTCTTTTGTTGTTATTTTTCGATAAAGAATATGAACGCTAGCTCTTATGT 2
146 sAD CTTTTGACATTTCTTTTGTTGTTATTTTTCGATAAAGAATATGAACGCTAGCTCTTATGT 2
147 sAD CTTAAAAAAAAAAAAAATCTGTGAACTTTCGAAAGCATAGGAGCAACTAGGAGATTTATG 6
148 mAD CTTAAAAAAAAAAAAAATCTGTGAACTTTCGAAAGCATAGGAGCAACTAGGAGATTTATG 6
149 sAD ACTGGAGTTTTTCAAAGATTTTTTTGTATCGACTAGGGAGAGGCTTAGATACTTTAGTGT 7
150 mAD ACTGGAGTTTTTCAAAGATTTTTTTGTATCGACTAGGGAGAGGCTTAGATACTTTAGTGT 7
151 mAD GATGAGTAACATAGTAGAAAAAAATACTTCGATGTCACCTTTTTCTTTGCTCTTTGGTAG 20
152 sAD GATGAGTAACATAGTAGAAAAAAATACTTCGATGTCACCTTTTTCTTTGCTCTTTGGTAG 20
153 mAD AATATAGGAATATTAGTAAAATGGTGTATCGACCCAGCTCCACGTGGAGCTGGCTCCTCA 5
154 sAD AATATAGGAATATTAGTAAAATGGTGTATCGACCCAGCTCCACGTGGAGCTGGCTCCTCA 5
155 sAD ATAAAGAGCTCGGAAGTGAGCTCTTTAGTCGACTCTGCAATTTTTCGCATCAAAGTTCAC 7
156 mAD ATAAAGAGCTCGGAAGTGAGCTCTTTAGTCGACTCTGCAATTTTTCGCATCAAAGTTCAC 7
157 sAD GTCACAGAGATCTAATCCTATGTTTTCTTCGACACAACGTGTTAGATTCTACCAAGAACT 4
158 mAD GTCACAGAGATCTAATCCTATGTTTTCTTCGACACAACGTGTTAGATTCTACCAAGAACT 4
159 sAD GTTACTTTACAGTAATATAATTTGTAACTCGAGTCACTCCTTTTTTTTAATTTTAAGTAT 6
160 mAD GTTACTTTACAGTAATATAATTTGTAACTCGAGTCACTCCTTTTTTTTAATTTTAAGTAT 6
161 mAD TTGTGCTTTTATTCCAATGTTTAATTTATCGATAGCCCAGGAAAAGAGCAAAATTCAAAG 10
162 sAD TTGTGCTTTTATTCCAATGTTTAATTTATCGATAGCCCAGGAAAAGAGCAAAATTCAAAG 10
163 sAD GTACTATAGTGACAAAGTAGTTGTCACATCGAAGGAAAAAATTGATATACAGAATGAAGC 2
164 mAD GTACTATAGTGACAAAGTAGTTGTCACATCGAAGGAAAAAATTGATATACAGAATGAAGC 2
165 sAD ACAAGATCCTTGAGAATCATTTCTGCCTTCGAATCTTGATAAGAGAAATGCCAAGAGGTT 1
166 mAD ACAAGATCCTTGAGAATCATTTCTGCCTTCGAATCTTGATAAGAGAAATGCCAAGAGGTT 1
167 sAD TGTCAATTTTCAATATAATTCATACAGTTCGAGTAAAGGTGGACTTGACTTGAGAAGATA 1
168 mAD TGTCAATTTTCAATATAATTCATACAGTTCGAGTAAAGGTGGACTTGACTTGAGAAGATA 1
169 sAD TTCTTTTATTTCATATAAAGATGAAGTCTCGAGACCTCATGACAATCTCCAAAAGTAGGT 10
170 mAD TTCTTTTATTTCATATAAAGATGAAGTCTCGAGACCTCATGACAATCTCCAAAAGTAGGT 10
171 sAD TTCTTGAACTAAAGATCTTAAAAGGCCTTCGAATTTCCTAACTTCCAGGATGATATTCTT 12
172 mAD TTCTTGAACTAAAGATCTTAAAAGGCCTTCGAATTTCCTAACTTCCAGGATGATATTCTT 12
173 mAD AAATATTCAAGATTCAGATGAATTCAAATCGATGCTACATATGATTGCTTGATTTCTAAA 13
174 sAD AAATATTCAAGATTCAGATGAATTCAAATCGATGCTACATATGATTGCTTGATTTCTAAA 13
175 mAD TTCCTTTATATTTTGTTTGTCTTCTTTATCGAGTTCTTCTCTTAGAAATATTTCCTGACA 15
176 sAD TTCCTTTATATTTTGTTTGTCTTCTTTATCGAGTTCTTCTCTTAGAAATATTTCCTGACA 15
177 sAD TTAAATATATCATGATTTTAAATGTTCTTCGATGAGTGAATGAGGGAACAAGTAATGTCT 19
178 mAD TTAAATATATCATGATTTTAAATGTTCTTCGATGAGTGAATGAGGGAACAAGTAATGTCT 19
179 mAD TATTCAGTATCTACTAGGGAGGATTTAATCGAAACCCATAAAATGTACAACACAACAGGA 3
180 sAD TATTCAGTATCTACTAGGGAGGATTTAATCGAAACCCATAAAATGTACAACACAACAGGA 3
181 mAD TTTAGTATTAGAAATGTTTTGGTCTTTATCGAGATGAAGTGTGTGAAAGAAAAGTTACTG 3
182 sAD TTTAGTATTAGAAATGTTTTGGTCTTTATCGAGATGAAGTGTGTGAAAGAAAAGTTACTG 3
183 mAD ATATATGACCTAACCTATTAAAAAGAGATCGAGTAGGAGGCTTAACATTGTTTTTCTTAG 4
184 sAD ATATATGACCTAACCTATTAAAAAGAGATCGAGTAGGAGGCTTAACATTGTTTTTCTTAG 4
185 sAD CATGGCTTCTTTCCTAGAAAAATTGTCTTCGAATGAGACATAAGTAGTGATTTGAAGAAT 6
186 mAD CATGGCTTCTTTCCTAGAAAAATTGTCTTCGAATGAGACATAAGTAGTGATTTGAAGAAT 6
187 sAD TTAATAGCAAAAAGATCAATATCTACTTTCGACTGGGAGAAAAGAATGAAAAATGTTAAA 8
188 mAD TTAATAGCAAAAAGATCAATATCTACTTTCGACTGGGAGAAAAGAATGAAAAATGTTAAA 8
189 sAD CTAAAATGAATCCTAAAGGTCTTTTTGTTCGATTTTGAAAAGCACATGTTTCCTTCCTTT 8
190 mAD CTAAAATGAATCCTAAAGGTCTTTTTGTTCGATTTTGAAAAGCACATGTTTCCTTCCTTT 8
191 sAD TAAATGTGAGCTACAGTTTATCTACAAATCGATTTTTTCATTTTAGGTTGTGAAGACTGT X
192 mAD TAAATGTGAGCTACAGTTTATCTACAAATCGATTTTTTCATTTTAGGTTGTGAAGACTGT X
193 mAD TATAAATACCAGAGAAGAAGCCATATTTTCGAAAATATTTGACATAGTTGATCACTTCCT 2
194 sAD TATAAATACCAGAGAAGAAGCCATATTTTCGAAAATATTTGACATAGTTGATCACTTCCT 2
195 mAD TGTTGTGAACTTTTGAAACAAATTTGTTTCGAGATCTATAATAAAGCAAAGGAGAGTCTC 6
196 sAD TGTTGTGAACTTTTGAAACAAATTTGTTTCGAGATCTATAATAAAGCAAAGGAGAGTCTC 6
197 sAD TATAAATACCAGAGAAGAAGCCATATTTTCGAATCAGTAATCTTTCTTCTGGGAATCTAG 2
198 mAD TATAAATACCAGAGAAGAAGCCATATTTTCGAATCAGTAATCTTTCTTCTGGGAATCTAG 2
199 sAD CTGTTTCTTACTTCTGAAACTTACAATTTCGAATTATGTTTCTGTCTCTTCCTTTCCTGT 8
200 mAD CTGTTTCTTACTTCTGAAACTTACAATTTCGAATTATGTTTCTGTCTCTTCCTTTCCTGT 8
201 sAD TTAGAGAATGAGAAAGACATGTCCTTAATCGATATAACTCTCAAATTTTGCCTAAATGAG 11
202 mAD TTAGAGAATGAGAAAGACATGTCCTTAATCGATATAACTCTCAAATTTTGCCTAAATGAG 11
203 sAD GTTAACATAGCTAAGTACCTCCGAAATATCGATGTCATATTTTATGTGTAATATATATGT 13
204 mAD GTTAACATAGCTAAGTACCTCCGAAATATCGATGTCATATTTTATGTGTAATATATATGT 13
205 sAD TTCTCTTCTTTATTGCATTAATCTGGTTTCGATTTCACCAAGTTTGCAAAAGATTCTGTG 2
206 mAD TTCTCTTCTTTATTGCATTAATCTGGTTTCGATTTCACCAAGTTTGCAAAAGATTCTGTG 2
207 mAD ATTTACTCAAACTTCCTAAGTGCTTATTTCGAAAGTTGATGCCAAATTGGGAAGTAAGAC 3
208 sAD ATTTACTCAAACTTCCTAAGTGCTTATTTCGAAAGTTGATGCCAAATTGGGAAGTAAGAC 3
209 mAD TCTAACCATTATGAGTAGATATTAATCTTCGAGTGGTGATATATTTGACCAGGGAAATAA 14
210 sAD TCTAACCATTATGAGTAGATATTAATCTTCGAGTGGTGATATATTTGACCAGGGAAATAA 14
211 sAD TACATTTTTAGCTCATCATAAAAGATATTCGACTCTGGGTTTGACACACATTAGTTTCTT 1
212 mAD TACATTTTTAGCTCATCATAAAAGATATTCGACTCTGGGTTTGACACACATTAGTTTCTT 1
213 mAD ATGTATTTTTCACAATATGAATTAAAAGTCGACTGATACAACTGACAGGTAGATAGCATT 10
214 sAD ATGTATTTTTCACAATATGAATTAAAAGTCGACTGATACAACTGACAGGTAGATAGCATT 10
215 sAD CAGTTTTTTAACACCACTGTTGGTGATTTCGATATTACCTTTTTTCTGGAACCATCTTTC 10
216 mAD CAGTTTTTTAACACCACTGTTGGTGATTTCGATATTACCTTTTTTCTGGAACCATCTTTC 10
217 mAD ATGAGACCAAATTACCCTTTGAATTCTCTCGAAGCTTGTTTTCTTTCACACTCCTAGTGC 10
218 sAD ATGAGACCAAATTACCCTTTGAATTCTCTCGAAGCTTGTTTTCTTTCACACTCCTAGTGC 10
219 mAD ACAGATTAAAACTATGAGGATATACCATTCGACATCTTTCATATCTGATTCTTTTTCCTT 12
220 sAD ACAGATTAAAACTATGAGGATATACCATTCGACATCTTTCATATCTGATTCTTTTTCCTT 12
表3.b5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
111 99005576 99005607 99054128 99054159 12 99001606 99005607 99054128 99058129
112 99005576 99005607 99054128 99054159 12 99001606 99005607 99054128 99058129
113 157433299 157433330 157514884 157514915 6 157429329 157433330 157510914 157514915
114 157433299 157433330 157514884 157514915 6 157429329 157433330 157510914 157514915
115 147568821 147568852 147649122 147649153 7 147564851 147568852 147649122 147653123
116 147568821 147568852 147649122 147649153 7 147564851 147568852 147649122 147653123
117 34062321 34062352 34131004 34131035 21 34062321 34066322 34127034 34131035
118 34062321 34062352 34131004 34131035 21 34062321 34066322 34127034 34131035
119 121118423 121118454 121226096 121226127 10 121118423 121122424 121222126 121226127
120 121118423 121118454 121226096 121226127 10 121118423 121122424 121222126 121226127
121 42385888 42385919 42471538 42471569 5 42381918 42385919 42467568 42471569
122 42385888 42385919 42471538 42471569 5 42381918 42385919 42467568 42471569
123 159206195 159206226 159243092 159243123 5 159206195 159210196 159239122 159243123
124 159206195 159206226 159243092 159243123 5 159206195 159210196 159239122 159243123
125 96265261 96265292 96328347 96328378 15 96265261 96269262 96328347 96332348
126 96265261 96265292 96328347 96328378 15 96265261 96269262 96328347 96332348
127 158448894 158448925 158477705 158477736 6 158444924 158448925 158473735 158477736
128 158448894 158448925 158477705 158477736 6 158444924 158448925 158473735 158477736
129 99298431 99298462 99373432 99373463 13 99298431 99302432 99373432 99377433
130 99298431 99298462 99373432 99373463 13 99298431 99302432 99373432 99377433
131 120020754 120020785 120066945 120066976 11 120016784 120020785 120066945 120070946
132 120020754 120020785 120066945 120066976 11 120016784 120020785 120066945 120070946
133 74830356 74830387 74873740 74873771 14 74830356 74834357 74873740 74877741
134 74830356 74830387 74873740 74873771 14 74830356 74834357 74873740 74877741
135 121477867 121477898 121570719 121570750 10 121477867 121481868 121566749 121570750
136 121477867 121477898 121570719 121570750 10 121477867 121481868 121566749 121570750
137 23148292 23148323 23204130 23204161 13 23148292 23152293 23204130 23208131
138 23148292 23148323 23204130 23204161 13 23148292 23152293 23204130 23208131
139 45996676 45996707 46057524 46057555 13 45996676 46000677 46057524 46061525
140 45996676 45996707 46057524 46057555 13 45996676 46000677 46057524 46061525
141 96275929 96275960 96328347 96328378 15 96275929 96279930 96328347 96332348
142 96275929 96275960 96328347 96328378 15 96275929 96279930 96328347 96332348
143 65243941 65243972 65289753 65289784 2 65239971 65243972 65289753 65293754
144 65243941 65243972 65289753 65289784 2 65239971 65243972 65289753 65293754
145 79971437 79971468 80055013 80055044 2 79971437 79975438 80051043 80055044
146 79971437 79971468 80055013 80055044 2 79971437 79975438 80051043 80055044
147 23219349 23219380 23277123 23277154 6 23219349 23223350 23273153 23277154
148 23219349 23219380 23277123 23277154 6 23219349 23223350 23273153 23277154
149 155744301 155744332 155779388 155779419 7 155740331 155744332 155779388 155783389
150 155744301 155744332 155779388 155779419 7 155740331 155744332 155779388 155783389
151 8541347 8541378 8590421 8590452 20 8537377 8541378 8590421 8594422
152 8541347 8541378 8590421 8590452 20 8537377 8541378 8590421 8594422
153 173916958 173916989 173969421 173969452 5 173916958 173920959 173969421 173973422
154 173916958 173916989 173969421 173969452 5 173916958 173920959 173969421 173973422
155 117292584 117292615 117366498 117366529 7 117292584 117296585 117362528 117366529
156 117292584 117292615 117366498 117366529 7 117292584 117296585 117362528 117366529
157 151328386 151328417 151358698 151358729 4 151328386 151332387 151358698 151362699
158 151328386 151328417 151358698 151358729 4 151328386 151332387 151358698 151362699
159 82026159 82026190 82077947 82077978 6 82026159 82030160 82077947 82081948
160 82026159 82026190 82077947 82077978 6 82026159 82030160 82077947 82081948
161 104234446 104234477 104264982 104265013 10 104234446 104238447 104264982 104268983
162 104234446 104234477 104264982 104265013 10 104234446 104238447 104264982 104268983
163 77504275 77504306 77514867 77514898 2 77500305 77504306 77514867 77518868
164 77504275 77504306 77514867 77514898 2 77500305 77504306 77514867 77518868
165 76032659 76032690 76079501 76079532 1 76032659 76036660 76075531 76079532
166 76032659 76032690 76079501 76079532 1 76032659 76036660 76075531 76079532
167 8424469 8424500 8478289 8478320 1 8420499 8424500 8478289 8482290
168 8424469 8424500 8478289 8478320 1 8420499 8424500 8478289 8482290
169 97762614 97762645 97793747 97793778 10 97762614 97766615 97789777 97793778
170 97762614 97762645 97793747 97793778 10 97762614 97766615 97789777 97793778
171 75072794 75072825 75143109 75143140 12 75068824 75072825 75139139 75143140
172 75072794 75072825 75143109 75143140 12 75068824 75072825 75139139 75143140
173 51302963 51302994 51323631 51323662 13 51302963 51306964 51323631 51327632
174 51302963 51302994 51323631 51323662 13 51302963 51306964 51323631 51327632
175 77328486 77328517 77382463 77382494 15 77328486 77332487 77382463 77386464
176 77328486 77328517 77382463 77382494 15 77328486 77332487 77382463 77386464
177 56925538 56925569 56987150 56987181 19 56921568 56925569 56987150 56991151
178 56925538 56925569 56987150 56987181 19 56921568 56925569 56987150 56991151
179 105438463 105438494 105507308 105507339 3 105434493 105438494 105503338 105507339
180 105438463 105438494 105507308 105507339 3 105434493 105438494 105503338 105507339
181 16444934 16444965 16479555 16479586 3 16440964 16444965 16475585 16479586
182 16444934 16444965 16479555 16479586 3 16440964 16444965 16475585 16479586
183 125340607 125340638 125392915 125392946 4 125340607 125344608 125392915 125396916
184 125340607 125340638 125392915 125392946 4 125340607 125344608 125392915 125396916
185 168789036 168789067 168918636 168918667 6 168789036 168793037 168918636 168922637
186 168789036 168789067 168918636 168918667 6 168789036 168793037 168918636 168922637
187 109580000 109580031 109640164 109640195 8 109580000 109584001 109636194 109640195
188 109580000 109580031 109640164 109640195 8 109580000 109584001 109636194 109640195
189 28475847 28475878 28536205 28536236 8 28471877 28475878 28536205 28540206
190 28475847 28475878 28536205 28536236 8 28471877 28475878 28536205 28540206
191 111110469 111110500 111175862 111175893 X 111106499 111110500 111171892 111175893
192 111110469 111110500 111175862 111175893 X 111106499 111110500 111171892 111175893
193 38114263 38114294 38179203 38179234 2 38110293 38114294 38179203 38183204
194 38114263 38114294 38179203 38179234 2 38110293 38114294 38179203 38183204
195 115984820 115984851 116077719 116077750 6 115980850 115984851 116073749 116077750
196 115984820 115984851 116077719 116077750 6 115980850 115984851 116073749 116077750
197 38114263 38114294 38180947 38180978 2 38110293 38114294 38176977 38180978
198 38114263 38114294 38180947 38180978 2 38110293 38114294 38176977 38180978
199 22651886 22651917 22674453 22674484 8 22647916 22651917 22670483 22674484
200 22651886 22651917 22674453 22674484 8 22647916 22651917 22670483 22674484
201 133325771 133325802 133378245 133378276 11 133321801 133325802 133378245 133382246
202 133325771 133325802 133378245 133378276 11 133321801 133325802 133378245 133382246
203 32247490 32247521 32296396 32296427 13 32247490 32251491 32296396 32300397
204 32247490 32247521 32296396 32296427 13 32247490 32251491 32296396 32300397
205 102956535 102956566 102983000 102983031 2 102952565 102956566 102983000 102987001
206 102956535 102956566 102983000 102983031 2 102952565 102956566 102983000 102987001
207 65827279 65827310 65903659 65903690 3 65827279 65831280 65899689 65903690
208 65827279 65827310 65903659 65903690 3 65827279 65831280 65899689 65903690
209 68260022 68260053 68327682 68327713 14 68260022 68264023 68323712 68327713
210 68260022 68260053 68327682 68327713 14 68260022 68264023 68323712 68327713
211 13952953 13952984 14008502 14008533 1 13948983 13952984 14004532 14008533
212 13952953 13952984 14008502 14008533 1 13948983 13952984 14004532 14008533
213 121570719 121570750 121690817 121690848 10 121566749 121570750 121690817 121694818
214 121570719 121570750 121690817 121690848 10 121566749 121570750 121690817 121694818
215 25034559 25034590 25084183 25084214 10 25034559 25038560 25080213 25084214
216 25034559 25034590 25084183 25084214 10 25034559 25038560 25080213 25084214
217 76412044 76412075 76458091 76458122 10 76408074 76412075 76458091 76462092
218 76412044 76412075 76458091 76458122 10 76408074 76412075 76458091 76462092
219 10096371 10096402 10158041 10158072 12 10096371 10100372 10154071 10158072
220 10096371 10096402 10158041 10158072 12 10096371 10100372 10154071 10158072
表3.b6
   探針 PCR- 引子 1_ID PCR_ 引子 1
111 ORF12_12_99003375_99005607_99054128_99056579_FR OBD159_1581 TCAAAACCTGACATAAATGCCTCA
112 ORF12_12_99003375_99005607_99054128_99056579_FR OBD159_1581 TCAAAACCTGACATAAATGCCTCA
113 ORF12_6_157429181_157433330_157512149_157514915_FF OBD159_1585 AGCGGTGTGCCTGTGTCTAATGAACG
114 ORF12_6_157429181_157433330_157512149_157514915_FF OBD159_1585 AGCGGTGTGCCTGTGTCTAATGAACG
115 ORF12_7_147567494_147568852_147649122_147653562_FR OBD159_1589 CAGGTGTTACCAGCATCCTCTCCCTA
116 ORF12_7_147567494_147568852_147649122_147653562_FR OBD159_1589 CAGGTGTTACCAGCATCCTCTCCCTA
117 ORF120_21_34062321_34063413_34127427_34131035_RF OBD159_1593 CACTGCTCGGCTTTGTGTTCAAGGCA
118 ORF120_21_34062321_34063413_34127427_34131035_RF OBD159_1593 CACTGCTCGGCTTTGTGTTCAAGGCA
119 ORF121_10_121118423_121121606_121215466_121226127_RF OBD159_1597 TGTTATGTTCATTCTCTGTGCCAGGC
120 ORF121_10_121118423_121121606_121215466_121226127_RF OBD159_1597 TGTTATGTTCATTCTCTGTGCCAGGC
121 ORF122_5_42377041_42385919_42468953_42471569_FF OBD159_1601 GGCAAAACAACTTCCCACTGACCTGT
122 ORF122_5_42377041_42385919_42468953_42471569_FF OBD159_1601 GGCAAAACAACTTCCCACTGACCTGT
123 ORF123_5_159206195_159208288_159235024_159243123_RF OBD159_1605 GCTGATACCTGAAGCGTGAGAAACAG
124 ORF123_5_159206195_159208288_159235024_159243123_RF OBD159_1605 GCTGATACCTGAAGCGTGAGAAACAG
125 ORF125_15_96265261_96271086_96328347_96331473_RR OBD159_1609 CCCTTCCCACTGGTTCTAATGACATC
126 ORF125_15_96265261_96271086_96328347_96331473_RR OBD159_1609 CCCTTCCCACTGGTTCTAATGACATC
127 ORF125_6_158443203_158448925_158476552_158477736_FF OBD159_1613 ATTTTGTGTCACTGTGCTGTTGTT
128 ORF125_6_158443203_158448925_158476552_158477736_FF OBD159_1613 ATTTTGTGTCACTGTGCTGTTGTT
129 ORF126_13_99298431_99304510_99373432_99375888_RR OBD159_1617 GCATCCCACAGTTTTCACAGGTA
130 ORF126_13_99298431_99304510_99373432_99375888_RR OBD159_1617 GCATCCCACAGTTTTCACAGGTA
131 ORF127_11_120012095_120020785_120066945_120072959_FR OBD159_1621 GTGGTGGTGGTTACATAAGGGAAAAC
132 ORF127_11_120012095_120020785_120066945_120072959_FR OBD159_1621 GTGGTGGTGGTTACATAAGGGAAAAC
133 ORF128_14_74830356_74835394_74873740_74878249_RR OBD159_1625 CAAACAATGGGACACCAAGTAGCCCT
134 ORF128_14_74830356_74835394_74873740_74878249_RR OBD159_1625 CAAACAATGGGACACCAAGTAGCCCT
135 ORF13_10_121477867_121479994_121564423_121570750_RF OBD159_1629 GGAGAAGGTTCCAGAAGCCGCCT
136 ORF13_10_121477867_121479994_121564423_121570750_RF OBD159_1629 GGAGAAGGTTCCAGAAGCCGCCT
137 ORF13_13_23148292_23151659_23204130_23213800_RR OBD159_1633 CAAAGTGCTGGGATTACAGGCAT
138 ORF13_13_23148292_23151659_23204130_23213800_RR OBD159_1633 CAAAGTGCTGGGATTACAGGCAT
139 ORF13_13_45996676_46000524_46057524_46060260_RR OBD159_1637 ATTGCCAGCATCACTCTTCTTTGC
140 ORF13_13_45996676_46000524_46057524_46060260_RR OBD159_1637 ATTGCCAGCATCACTCTTCTTTGC
141 ORF13_15_96275929_96277834_96328347_96331473_RR OBD159_1641 TAACTGGATTTTCTCTGGAATGAAGC
142 ORF13_15_96275929_96277834_96328347_96331473_RR OBD159_1641 TAACTGGATTTTCTCTGGAATGAAGC
143 ORF13_2_65241569_65243972_65289753_65296291_FR OBD159_1645 GGTTCTGAGTGATGAAGGCAAGT
144 ORF13_2_65241569_65243972_65289753_65296291_FR OBD159_1645 GGTTCTGAGTGATGAAGGCAAGT
145 ORF13_2_79971437_79976448_80050108_80055044_RF OBD159_1649 GGGTGAGTGGGAAGAATGGTGCTATT
146 ORF13_2_79971437_79976448_80050108_80055044_RF OBD159_1649 GGGTGAGTGGGAAGAATGGTGCTATT
147 ORF13_6_23219349_23223439_23271280_23277154_RF OBD159_1653 AATCACTTCAACCCAGGAGGTGGA
148 ORF13_6_23219349_23223439_23271280_23277154_RF OBD159_1653 AATCACTTCAACCCAGGAGGTGGA
149 ORF13_7_155741321_155744332_155779388_155780808_FR OBD159_1657 TATTTTACACGGAGTCTGTGGATA
150 ORF13_7_155741321_155744332_155779388_155780808_FR OBD159_1657 TATTTTACACGGAGTCTGTGGATA
151 ORF131_20_8536736_8541378_8590421_8594259_FR OBD159_1661 GCTGGTGTGCCACTAATGCTCTCCAA
152 ORF131_20_8536736_8541378_8590421_8594259_FR OBD159_1661 GCTGGTGTGCCACTAATGCTCTCCAA
153 ORF132_5_173916958_173918697_173969421_173970862_RR OBD159_1665 CTCTCCCCACCATTCCTACCTGA
154 ORF132_5_173916958_173918697_173969421_173970862_RR OBD159_1665 CTCTCCCCACCATTCCTACCTGA
155 ORF132_7_117292584_117297912_117353457_117366529_RF OBD159_1669 AGCCTGGGCAATGGAGTGAGACT
156 ORF132_7_117292584_117297912_117353457_117366529_RF OBD159_1669 AGCCTGGGCAATGGAGTGAGACT
157 ORF133_4_151328386_151338975_151358698_151359731_RR OBD159_1673 GTTCTCCCCTTCTGTCTTTTCACTTT
158 ORF133_4_151328386_151338975_151358698_151359731_RR OBD159_1673 GTTCTCCCCTTCTGTCTTTTCACTTT
159 ORF134_6_82026159_82034690_82077947_82085585_RR OBD159_1677 GATAACATTCACATTTTGACCAGC
160 ORF134_6_82026159_82034690_82077947_82085585_RR OBD159_1677 GATAACATTCACATTTTGACCAGC
161 ORF138_10_104234446_104238473_104264982_104269909_RR OBD159_1681 GCCAAATTTTACCTTTACATT
162 ORF138_10_104234446_104238473_104264982_104269909_RR OBD159_1681 GCCAAATTTTACCTTTACATT
163 ORF138_2_77502067_77504306_77514867_77519288_FR OBD159_1685 GCTAAATCCAGACTGCCACCATT
164 ORF138_2_77502067_77504306_77514867_77519288_FR OBD159_1685 GCTAAATCCAGACTGCCACCATT
165 ORF14_1_76032659_76035831_76077590_76079532_RF OBD159_1689 ATGATTTCTACCCTTGGTCAGCAGGT
166 ORF14_1_76032659_76035831_76077590_76079532_RF OBD159_1689 ATGATTTCTACCCTTGGTCAGCAGGT
167 ORF14_1_8423193_8424500_8478289_8482650_FR OBD159_1693 TCCCTGTGTTTGAGACCCGCCAG
168 ORF14_1_8423193_8424500_8478289_8482650_FR OBD159_1693 TCCCTGTGTTTGAGACCCGCCAG
169 ORF14_10_97762614_97766905_97790822_97793778_RF OBD159_1697 GAACTGCTTCTTGCCTCCCTTCC
170 ORF14_10_97762614_97766905_97790822_97793778_RF OBD159_1697 GAACTGCTTCTTGCCTCCCTTCC
171 ORF14_12_75070822_75072825_75141366_75143140_FF OBD159_1701 CTGAGTGCCTGGGAATGACAGTC
172 ORF14_12_75070822_75072825_75141366_75143140_FF OBD159_1701 CTGAGTGCCTGGGAATGACAGTC
173 ORF14_13_51302963_51306635_51323631_51326485_RR OBD159_1705 CTCAAACACTGGCAACGCATTTTCCC
174 ORF14_13_51302963_51306635_51323631_51326485_RR OBD159_1705 CTCAAACACTGGCAACGCATTTTCCC
175 ORF14_15_77328486_77331349_77382463_77385598_RR OBD159_1709 CTCAGTTTCCTCACCAATCAGACTAC
176 ORF14_15_77328486_77331349_77382463_77385598_RR OBD159_1709 CTCAGTTTCCTCACCAATCAGACTAC
177 ORF14_19_56921649_56925569_56987150_56988841_FR OBD159_1713 CAGGCTGAGGCACTCTGGTCTAT
178 ORF14_19_56921649_56925569_56987150_56988841_FR OBD159_1713 CAGGCTGAGGCACTCTGGTCTAT
179 ORF14_3_105431137_105438494_105503436_105507339_FF OBD159_1717 CTTGGCATTTTACTTACTTATCTT
180 ORF14_3_105431137_105438494_105503436_105507339_FF OBD159_1717 CTTGGCATTTTACTTACTTATCTT
181 ORF14_3_16438382_16444965_16476728_16479586_FF OBD159_1721 CAACCACCATCACTCGCTGTTTTACC
182 ORF14_3_16438382_16444965_16476728_16479586_FF OBD159_1721 CAACCACCATCACTCGCTGTTTTACC
183 ORF14_4_125340607_125343598_125392915_125397466_RR OBD159_1725 GCCACCGCAACTGCTACACAACTACT
184 ORF14_4_125340607_125343598_125392915_125397466_RR OBD159_1725 GCCACCGCAACTGCTACACAACTACT
185 ORF14_6_168789036_168790083_168918636_168926703_RR OBD159_1729 CTGACACGCCTGCCTTCCTCTTT
186 ORF14_6_168789036_168790083_168918636_168926703_RR OBD159_1729 CTGACACGCCTGCCTTCCTCTTT
187 ORF14_8_109580000_109582610_109632260_109640195_RF OBD159_1733 AAGATGAAGAGAGATGAGGGAGAGGC
188 ORF14_8_109580000_109582610_109632260_109640195_RF OBD159_1733 AAGATGAAGAGAGATGAGGGAGAGGC
189 ORF14_8_28471461_28475878_28536205_28541536_FR OBD159_1737 ATTGACTAACAACAACAAGAAAGC
190 ORF14_8_28471461_28475878_28536205_28541536_FR OBD159_1737 ATTGACTAACAACAACAAGAAAGC
191 ORF14_X_111096546_111110500_111165610_111175893_FF OBD159_1741 GAACTGAGCATAATCCTTCTTGTGAC
192 ORF14_X_111096546_111110500_111165610_111175893_FF OBD159_1741 GAACTGAGCATAATCCTTCTTGTGAC
193 ORF140_2_38110623_38114294_38179203_38180978_FR OBD159_1745 TGTGAAGGGCAGTGAATAAAGGATTA
194 ORF140_2_38110623_38114294_38179203_38180978_FR OBD159_1745 TGTGAAGGGCAGTGAATAAAGGATTA
195 ORF141_6_115981175_115984851_116074475_116077750_FF OBD159_1749 TGCCATTCACACAAAGTCTAAGGG
196 ORF141_6_115981175_115984851_116074475_116077750_FF OBD159_1749 TGCCATTCACACAAAGTCTAAGGG
197 ORF142_2_38110623_38114294_38179203_38180978_FF OBD159_1753 TGTGAAGGGCAGTGAATAAAGGATTA
198 ORF142_2_38110623_38114294_38179203_38180978_FF OBD159_1753 TGTGAAGGGCAGTGAATAAAGGATTA
199 ORF142_8_22647922_22651917_22671292_22674484_FF OBD159_1757 GAAGCCACTCTGATTCCCATCCTTTG
200 ORF142_8_22647922_22651917_22671292_22674484_FF OBD159_1757 GAAGCCACTCTGATTCCCATCCTTTG
201 ORF144_11_133321952_133325802_133378245_133382756_FR OBD159_1761 GCAGGAGGGATGACTACTTGCCAA
202 ORF144_11_133321952_133325802_133378245_133382756_FR OBD159_1761 GCAGGAGGGATGACTACTTGCCAA
203 ORF144_13_32247490_32254361_32296396_32300347_RR OBD159_1765 GAAATAACTGTCAAATAAGTCTTC
204 ORF144_13_32247490_32254361_32296396_32300347_RR OBD159_1765 GAAATAACTGTCAAATAAGTCTTC
205 ORF147_2_102946170_102956566_102983000_102995309_FR OBD159_1769 CTATTTGCTTCCATCTCTTCTTCAAG
206 ORF147_2_102946170_102956566_102983000_102995309_FR OBD159_1769 CTATTTGCTTCCATCTCTTCTTCAAG
207 ORF148_3_65827279_65831993_65898255_65903690_RF OBD159_1773 CCTAAGACAGAGGGAAAAGAAGGTA
208 ORF148_3_65827279_65831993_65898255_65903690_RF OBD159_1773 CCTAAGACAGAGGGAAAAGAAGGTA
209 ORF149_14_68260022_68266399_68325745_68327713_RF OBD159_1777 GCCAAAGACTCCTCTGGGAATCC
210 ORF149_14_68260022_68266399_68325745_68327713_RF OBD159_1777 GCCAAAGACTCCTCTGGGAATCC
211 ORF15_1_13945271_13952984_14001723_14008533_FF OBD159_1781 TTGTGCTGTGTGACCTTGGGATGTCC
212 ORF15_1_13945271_13952984_14001723_14008533_FF OBD159_1781 TTGTGCTGTGTGACCTTGGGATGTCC
213 ORF15_10_121564423_121570750_121690817_121692131_FR OBD159_1785 GAGGCTTCCACAGACAGAGAATA
214 ORF15_10_121564423_121570750_121690817_121692131_FR OBD159_1785 GAGGCTTCCACAGACAGAGAATA
215 ORF15_10_25034559_25040591_25081322_25084214_RF OBD159_1789 CCTCCAAACAGTAGCATCACATCACC
216 ORF15_10_25034559_25040591_25081322_25084214_RF OBD159_1789 CCTCCAAACAGTAGCATCACATCACC
217 ORF15_10_76410191_76412075_76458091_76462498_FR OBD159_1793 GCCAGCCTCTGTTTGCCAATGGT
218 ORF15_10_76410191_76412075_76458091_76462498_FR OBD159_1793 GCCAGCCTCTGTTTGCCAATGGT
219 ORF15_12_10096371_10100557_10157054_10158072_RF OBD159_1797 AGCCTGAGCAACAAGAGCGAAACT
220 ORF15_12_10096371_10100557_10157054_10158072_RF OBD159_1797 AGCCTGAGCAACAAGAGCGAAACT
表3.b7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
111 OBD159_1583 AGCCTTGCTGTTTCCATCGTGAAT OBD159_1581_1583 0.003298289
112 OBD159_1583 AGCCTTGCTGTTTCCATCGTGAAT OBD159_1581_1583 0.003298289
113 OBD159_1587 AAACCAAGCCAACAAGGAACCCATTC OBD159_1585_1587 0.001146182
114 OBD159_1587 AAACCAAGCCAACAAGGAACCCATTC OBD159_1585_1587 0.001146182
115 OBD159_1591 TGACTGGATAACCTCACAGAGTTTCC OBD159_1589_1591 0.001083337
116 OBD159_1591 TGACTGGATAACCTCACAGAGTTTCC OBD159_1589_1591 0.001083337
117 OBD159_1595 GACAACTGAACCTTCCAGCATCTTGA OBD159_1593_1595 0.000591066
118 OBD159_1595 GACAACTGAACCTTCCAGCATCTTGA OBD159_1593_1595 0.000591066
119 OBD159_1599 GCCTCTCTCCAAACAATCAGGGCTCT OBD159_1597_1599 0.000990022
120 OBD159_1599 GCCTCTCTCCAAACAATCAGGGCTCT OBD159_1597_1599 0.000990022
121 OBD159_1603 CGTTGACCTTCCTACTTATCTAAACA OBD159_1601_1603 0.001406379
122 OBD159_1603 CGTTGACCTTCCTACTTATCTAAACA OBD159_1601_1603 0.001406379
123 OBD159_1607 GCTTGCCACTGACTTGCTAAAATAAC OBD159_1605_1607 0.002050957
124 OBD159_1607 GCTTGCCACTGACTTGCTAAAATAAC OBD159_1605_1607 0.002050957
125 OBD159_1611 CCTCCTGAATGAGACTTCCATAGCAG OBD159_1609_1611 0.001445915
126 OBD159_1611 CCTCCTGAATGAGACTTCCATAGCAG OBD159_1609_1611 0.001445915
127 OBD159_1615 AAAGGAAACGCTTCTACACTGCTA OBD159_1613_1615 0.001481028
128 OBD159_1615 AAAGGAAACGCTTCTACACTGCTA OBD159_1613_1615 0.001481028
129 OBD159_1619 GCCTTATCCATCTTAGTGTTTTCAGA OBD159_1617_1619 0.000656997
130 OBD159_1619 GCCTTATCCATCTTAGTGTTTTCAGA OBD159_1617_1619 0.000656997
131 OBD159_1623 GCGAGAGAGAAGAGAGGCATCCACAT OBD159_1621_1623 0.000946101
132 OBD159_1623 GCGAGAGAGAAGAGAGGCATCCACAT OBD159_1621_1623 0.000946101
133 OBD159_1627 GCTAAGCATTCCACCACTACAGCCTA OBD159_1625_1627 0.000498191
134 OBD159_1627 GCTAAGCATTCCACCACTACAGCCTA OBD159_1625_1627 0.000498191
135 OBD159_1631 CCCAGAGGAGCAAACAAAGAGCC OBD159_1629_1631 0.000925033
136 OBD159_1631 CCCAGAGGAGCAAACAAAGAGCC OBD159_1629_1631 0.000925033
137 OBD159_1635 CTGACTCAATCAACCACAAACTAAAG OBD159_1633_1635 0.001554604
138 OBD159_1635 CTGACTCAATCAACCACAAACTAAAG OBD159_1633_1635 0.001554604
139 OBD159_1639 CTGCCCTGACTTCCCTAACCCTC OBD159_1637_1639 0.002206167
140 OBD159_1639 CTGCCCTGACTTCCCTAACCCTC OBD159_1637_1639 0.002206167
141 OBD159_1643 TGAGACTTCCATAGCAGATTACCTTT OBD159_1641_1643 0.002552583
142 OBD159_1643 TGAGACTTCCATAGCAGATTACCTTT OBD159_1641_1643 0.002552583
143 OBD159_1647 CATTTCTCATCCCAGGCATTTCAGA OBD159_1645_1647 0.001235373
144 OBD159_1647 CATTTCTCATCCCAGGCATTTCAGA OBD159_1645_1647 0.001235373
145 OBD159_1651 ACCTGAGTTCAAATCCCTCTGCTCTC OBD159_1649_1651 0.000308972
146 OBD159_1651 ACCTGAGTTCAAATCCCTCTGCTCTC OBD159_1649_1651 0.000308972
147 OBD159_1655 CCTTATGCTGTTTTATGTTCCTAA OBD159_1653_1655 0.001334444
148 OBD159_1655 CCTTATGCTGTTTTATGTTCCTAA OBD159_1653_1655 0.001334444
149 OBD159_1659 ATAACACTCCATTCACAAACTTTA OBD159_1657_1659 0.002743967
150 OBD159_1659 ATAACACTCCATTCACAAACTTTA OBD159_1657_1659 0.002743967
151 OBD159_1663 GTCACAGCAGCAATAGAAATAGCAAC OBD159_1661_1663 0.00077793
152 OBD159_1663 GTCACAGCAGCAATAGAAATAGCAAC OBD159_1661_1663 0.00077793
153 OBD159_1667 GGAGGTGATGGTGATGTGCCAGC OBD159_1665_1667 0.00207185
154 OBD159_1667 GGAGGTGATGGTGATGTGCCAGC OBD159_1665_1667 0.00207185
155 OBD159_1671 GAGAAGTCCTGAAGTAACGCTAC OBD159_1669_1671 0.000464028
156 OBD159_1671 GAGAAGTCCTGAAGTAACGCTAC OBD159_1669_1671 0.000464028
157 OBD159_1675 AGGTGGACCGAGGGACATTTACCAGT OBD159_1673_1675 0.000897879
158 OBD159_1675 AGGTGGACCGAGGGACATTTACCAGT OBD159_1673_1675 0.000897879
159 OBD159_1679 CTTGTGAAGTCTTTATTATTATGCT OBD159_1677_1679 0.001289242
160 OBD159_1679 CTTGTGAAGTCTTTATTATTATGCT OBD159_1677_1679 0.001289242
161 OBD159_1683 TGCATTTTATATTGAAAAGTT OBD159_1681_1683 0.001668215
162 OBD159_1683 TGCATTTTATATTGAAAAGTT OBD159_1681_1683 0.001668215
163 OBD159_1687 AGTGTGCTTGGTTGAACTGAATCATT OBD159_1685_1687 0.00035722
164 OBD159_1687 AGTGTGCTTGGTTGAACTGAATCATT OBD159_1685_1687 0.00035722
165 OBD159_1691 GGAGGGCATAATCTCTGTTCTGCTGC OBD159_1689_1691 0.002759986
166 OBD159_1691 GGAGGGCATAATCTCTGTTCTGCTGC OBD159_1689_1691 0.002759986
167 OBD159_1695 GCCTTCTCCCCACACCTGGTATT OBD159_1693_1695 0.000999054
168 OBD159_1695 GCCTTCTCCCCACACCTGGTATT OBD159_1693_1695 0.000999054
169 OBD159_1699 CCCTAACCTCCCCACACCTCCTT OBD159_1697_1699 0.001213842
170 OBD159_1699 CCCTAACCTCCCCACACCTCCTT OBD159_1697_1699 0.001213842
171 OBD159_1703 CAGAATGGGTCCGTCTCAGAGGC OBD159_1701_1703 0.001521449
172 OBD159_1703 CAGAATGGGTCCGTCTCAGAGGC OBD159_1701_1703 0.001521449
173 OBD159_1707 TTTCAGCATAGATTTTGGGCGAAGGC OBD159_1705_1707 0.001374847
174 OBD159_1707 TTTCAGCATAGATTTTGGGCGAAGGC OBD159_1705_1707 0.001374847
175 OBD159_1711 GCAGATTTGGTGTGGGTTAGAGAGGG OBD159_1709_1711 0.000546851
176 OBD159_1711 GCAGATTTGGTGTGGGTTAGAGAGGG OBD159_1709_1711 0.000546851
177 OBD159_1715 AAGGAGCGTTGCGGAATGGGAGC OBD159_1713_1715 0.000535081
178 OBD159_1715 AAGGAGCGTTGCGGAATGGGAGC OBD159_1713_1715 0.000535081
179 OBD159_1719 GTTTGTGTCCTTCCCTCTCCCTAT OBD159_1717_1719 0.001341809
180 OBD159_1719 GTTTGTGTCCTTCCCTCTCCCTAT OBD159_1717_1719 0.001341809
181 OBD159_1723 GCCTGGGCTATTAGAAACAGCATCAG OBD159_1721_1723 0.000916266
182 OBD159_1723 GCCTGGGCTATTAGAAACAGCATCAG OBD159_1721_1723 0.000916266
183 OBD159_1727 CTTTTGGGAGACCGTAGGATTTGTAG OBD159_1725_1727 0.001245559
184 OBD159_1727 CTTTTGGGAGACCGTAGGATTTGTAG OBD159_1725_1727 0.001245559
185 OBD159_1731 CCATCTCCTGCCCGAAGCCAGTT OBD159_1729_1731 0.001401855
186 OBD159_1731 CCATCTCCTGCCCGAAGCCAGTT OBD159_1729_1731 0.001401855
187 OBD159_1735 AAAATACCAGGCAGGTGGGAAGAAGG OBD159_1733_1735 0.000773504
188 OBD159_1735 AAAATACCAGGCAGGTGGGAAGAAGG OBD159_1733_1735 0.000773504
189 OBD159_1739 TTAGATGGATGAAAGAGATGAAAA OBD159_1737_1739 0.000994481
190 OBD159_1739 TTAGATGGATGAAAGAGATGAAAA OBD159_1737_1739 0.000994481
191 OBD159_1743 GATGGTTTCAGATACCTCCCAGATAC OBD159_1741_1743 0.001549662
192 OBD159_1743 GATGGTTTCAGATACCTCCCAGATAC OBD159_1741_1743 0.001549662
193 OBD159_1747 ATGGAAACTGGGAGAGGAGACAGC OBD159_1745_1747 0.002285957
194 OBD159_1747 ATGGAAACTGGGAGAGGAGACAGC OBD159_1745_1747 0.002285957
195 OBD159_1751 TTACCTTACTCATTGAACAGTTTT OBD159_1749_1751 0.001654806
196 OBD159_1751 TTACCTTACTCATTGAACAGTTTT OBD159_1749_1751 0.001654806
197 OBD159_1755 GGGCATTGGAAGTTCAAGCGACTAAC OBD159_1753_1755 0.001865788
198 OBD159_1755 GGGCATTGGAAGTTCAAGCGACTAAC OBD159_1753_1755 0.001865788
199 OBD159_1759 CCCCAAATGCTTCACTCTGGAAAG OBD159_1757_1759 0.001030812
200 OBD159_1759 CCCCAAATGCTTCACTCTGGAAAG OBD159_1757_1759 0.001030812
201 OBD159_1763 GTGCTGCCCACCATCACTAAACAAAT OBD159_1761_1763 0.000783894
202 OBD159_1763 GTGCTGCCCACCATCACTAAACAAAT OBD159_1761_1763 0.000783894
203 OBD159_1767 CACATCTAACACTTGACAGCATTA OBD159_1765_1767 0.001317268
204 OBD159_1767 CACATCTAACACTTGACAGCATTA OBD159_1765_1767 0.001317268
205 OBD159_1771 GCTACCATTCTCTTTTGGCTTTGAGC OBD159_1769_1771 0.00219463
206 OBD159_1771 GCTACCATTCTCTTTTGGCTTTGAGC OBD159_1769_1771 0.00219463
207 OBD159_1775 CGGAGCAAGAGCAGTTTGGCTGTGT OBD159_1773_1775 0.002134591
208 OBD159_1775 CGGAGCAAGAGCAGTTTGGCTGTGT OBD159_1773_1775 0.002134591
209 OBD159_1779 ATAGCAGCCAGTCTCCACACCCC OBD159_1777_1779 0.001397539
210 OBD159_1779 ATAGCAGCCAGTCTCCACACCCC OBD159_1777_1779 0.001397539
211 OBD159_1783 AGGGTGGCAAATCAAACCTACCTGA OBD159_1781_1783 0.000788302
212 OBD159_1783 AGGGTGGCAAATCAAACCTACCTGA OBD159_1781_1783 0.000788302
213 OBD159_1787 GCCGTCCCAGTAATAACTAAATGC OBD159_1785_1787 0.001998517
214 OBD159_1787 GCCGTCCCAGTAATAACTAAATGC OBD159_1785_1787 0.001998517
215 OBD159_1791 GGGTATCTCTTGAACTGATGACTCTT OBD159_1789_1791 0.001334933
216 OBD159_1791 GGGTATCTCTTGAACTGATGACTCTT OBD159_1789_1791 0.001334933
217 OBD159_1795 CCCTCTATGGGTGCTCAGACTGC OBD159_1793_1795 0.003048534
218 OBD159_1795 CCCTCTATGGGTGCTCAGACTGC OBD159_1793_1795 0.003048534
219 OBD159_1799 ATGGAAATGATAAGTTGAAGGTAT OBD159_1797_1799 0.00111867
220 OBD159_1799 ATGGAAATGATAAGTTGAAGGTAT OBD159_1797_1799 0.00111867
表3.b8
   基因
111 ANKS1B; rs7960581
112 ANKS1B; rs7960581
113 TMEM242; ZDHHC14; rs181143083
114 TMEM242; ZDHHC14; rs181143083
115 CNTNAP2; rs201076428; rs6944808
116 CNTNAP2; rs201076428; rs6944808
117 MRPS6; SLC5A3; rs2834319
118 MRPS6; SLC5A3; rs2834319
119 rs1907240; rs2257129; rs3943077; rs35668226
120 rs1907240; rs2257129; rs3943077; rs35668226
121 GHR; rs6898743
122 GHR; rs6898743
123 RNF145; rs2901184; rs10515778; rs55801554
124 RNF145; rs2901184; rs10515778; rs55801554
125 NR2F2; rs2398180; rs587777373
126 NR2F2; rs2398180; rs587777373
127 TULP4; rs9456307
128 TULP4; rs9456307
129 GPR183; UBAC2; rs9557195; rs9513593
130 GPR183; UBAC2; rs9557195; rs9513593
131 PVRL1; TRIM29
132 PVRL1; TRIM29
133 DLST; PROX2; YLPM1
134 DLST; PROX2; YLPM1
135 FGFR2; rs749474548; rs1057519795; rs1057520029; rs1057520027; rs879253720; rs121918508; rs1057519047; rs1057519854; rs777169135; rs121918509; rs1057519796; rs751047267; rs121918506; rs1057519797; rs121913476; rs1057519045; rs1057519901; rs1057519798; rs1057519799; rs1057519800; rs121918507; rs1057520044; rs751731391; rs387906677; rs1057519900; rs387906678; rs121913478; rs1057520028; rs121913477; rs879253721; rs121918490; rs121918502; rs121918494; rs121918491; rs121918492; rs121918496; rs121918487; rs121918488; rs121918495; rs121918489; rs1057519044; rs1057519043; rs387906676; rs1057519042; rs121918493; rs121918510; rs121918504; rs1057519791; rs121913475; rs1057519040; rs374608214; rs121918500; rs121918499; rs1057519039; rs121918501; rs121918497; rs1057519038; rs776587763; rs1057519036; rs879253718; rs121918505; rs779326224; rs387907372; rs77543610; rs121918498; rs79184941; rs3135753; rs11199993; rs755001161; rs148514974; rs10510097; rs4752569
136 FGFR2; rs749474548; rs1057519795; rs1057520029; rs1057520027; rs879253720; rs121918508; rs1057519047; rs1057519854; rs777169135; rs121918509; rs1057519796; rs751047267; rs121918506; rs1057519797; rs121913476; rs1057519045; rs1057519901; rs1057519798; rs1057519799; rs1057519800; rs121918507; rs1057520044; rs751731391; rs387906677; rs1057519900; rs387906678; rs121913478; rs1057520028; rs121913477; rs879253721; rs121918490; rs121918502; rs121918494; rs121918491; rs121918492; rs121918496; rs121918487; rs121918488; rs121918495; rs121918489; rs1057519044; rs1057519043; rs387906676; rs1057519042; rs121918493; rs121918510; rs121918504; rs1057519791; rs121913475; rs1057519040; rs374608214; rs121918500; rs121918499; rs1057519039; rs121918501; rs121918497; rs1057519038; rs776587763; rs1057519036; rs879253718; rs121918505; rs779326224; rs387907372; rs77543610; rs121918498; rs79184941; rs3135753; rs11199993; rs755001161; rs148514974; rs10510097; rs4752569
137 SGCG; rs76916029; rs764468720; rs138880406; rs781760379; rs200502077; rs797045106; rs570169794
138 SGCG; rs76916029; rs764468720; rs138880406; rs781760379; rs200502077; rs797045106; rs570169794
139 CPB2; ZC3H13; rs1926447; rs779491029; rs3742264
140 CPB2; ZC3H13; rs1926447; rs779491029; rs3742264
141 NR2F2; rs2398180; rs587777373
142 NR2F2; rs2398180; rs587777373
143 ACTR2; SPRED2; rs62139085
144 ACTR2; SPRED2; rs62139085
145 CTNNA2; rs6738962; rs13427272
146 CTNNA2; rs6738962; rs13427272
147 rs7771911
148 rs7771911
149 RBM33; SHH
150 RBM33; SHH
151 PLCB1; rs4432538
152 PLCB1; rs4432538
153 C5orf47; CPEB4; rs10516107; rs6861681; rs17076724; rs17076726; rs56163845; rs72812846; rs72812861
154 C5orf47; CPEB4; rs10516107; rs6861681; rs17076724; rs17076726; rs56163845; rs72812846; rs72812861
155 ASZ1; WNT2; rs114167782; rs749398878; rs3779547
156 ASZ1; WNT2; rs114167782; rs749398878; rs3779547
157 FAM160A1; SH3D19
158 FAM160A1; SH3D19
159 IBTK; rs10806235
160 IBTK; rs10806235
161 CFAP43; GSTO1; GSTO2; rs11191972; rs4925
162 CFAP43; GSTO1; GSTO2; rs11191972; rs4925
163 LRRTM4; rs61354037
164 LRRTM4; rs61354037
165 ST6GALNAC3; rs12095069
166 ST6GALNAC3; rs12095069
167 RERE; rs301807; rs301797; rs301798; rs172531; rs34976449; rs301819; rs159963; rs142472947; rs4908760; rs301806
168 RERE; rs301807; rs301797; rs301798; rs172531; rs34976449; rs301819; rs159963; rs142472947; rs4908760; rs301806
169 SFRP5; ZFYVE27; rs7072751
170 SFRP5; ZFYVE27; rs7072751
171 CAPS2; KCNC2
172 CAPS2; KCNC2
173 FAM124A; SERPINE3
174 FAM124A; SERPINE3
175 HMG20A; PEAK1
176 HMG20A; PEAK1
177 USP29; ZIM2
178 USP29; ZIM2
179 ALCAM; rs13070790
180 ALCAM; rs13070790
181 RFTN1; rs3856834
182 RFTN1; rs3856834
183 FAT4; rs1039808
184 FAT4; rs1039808
185 rs196458; rs116146467
186 rs196458; rs116146467
187 EBAG9; SYBU
188 EBAG9; SYBU
189 FBXO16; FZD3; rs17059209
190 FBXO16; FZD3; rs17059209
191 PAK3; rs121434612; rs780775497; rs121434613
192 PAK3; rs121434612; rs780775497; rs121434613
193 ATL2; CYP1B1
194 ATL2; CYP1B1
195 FRK; NT5DC1; rs1933737; rs9488822; rs3822857; rs868943; rs6909746; rs1999930
196 FRK; NT5DC1; rs1933737; rs9488822; rs3822857; rs868943; rs6909746; rs1999930
197 ATL2; CYP1B1
198 ATL2; CYP1B1
199 BIN3; EGR3; rs2280104
200 BIN3; EGR3; rs2280104
201 OPCML; rs7104890; rs4379857
202 OPCML; rs7104890; rs4379857
203 FRY; ZAR1L; rs56404467; rs56084662
204 FRY; ZAR1L; rs56404467; rs56084662
205 TMEM182; rs12105421
206 TMEM182; rs12105421
207 MAGI1; rs145965284
208 MAGI1; rs145965284
209 RAD51B; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566; rs1570106
210 RAD51B; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566; rs1570106
211 rs7542939
212 rs7542939
213 FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs1219515; rs1696803; rs755001161
214 FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs1219515; rs1696803; rs755001161
215 ENKUR; THNSL1
216 ENKUR; THNSL1
217 C10orf11; rs11593840; rs10509373
218 C10orf11; rs11593840; rs10509373
219 CLEC1A; CLEC7A; OLR1; rs16910526; rs16910527; rs7309123; rs2078178; rs3901533
220 CLEC1A; CLEC7A; OLR1; rs16910526; rs16910527; rs7309123; rs2078178; rs3901533
表3.b9
   探針 基因座
221 ORF15_16_62560699_62565069_62586208_62592959_FF rs150252171; rs288604
222 ORF15_16_62560699_62565069_62586208_62592959_FF rs150252171; rs288604
223 ORF15_2_47506510_47507935_47549933_47552565_RR KCNK12; MSH2; rs267608023
224 ORF15_2_47506510_47507935_47549933_47552565_RR KCNK12; MSH2; rs267608023
225 ORF15_20_19844341_19848170_19898126_19900554_FR RIN2; rs4813376; rs6046396; rs16981145
226 ORF15_20_19844341_19848170_19898126_19900554_FR RIN2; rs4813376; rs6046396; rs16981145
227 ORF15_3_107655921_107658466_107697731_107699826_FF BBX; rs11710737
228 ORF15_3_107655921_107658466_107697731_107699826_FF BBX; rs11710737
229 ORF15_3_39211112_39215294_39286446_39287590_RF CX3CR1; XIRP1; rs1877563; rs3732378; rs3732379; rs9868689; rs12636547; rs2669845; rs11715522; rs2853707
230 ORF15_3_39211112_39215294_39286446_39287590_RF CX3CR1; XIRP1; rs1877563; rs3732378; rs3732379; rs9868689; rs12636547; rs2669845; rs11715522; rs2853707
231 ORF15_6_154255952_154259046_154307704_154312070_FF CNKSR3; IPCEF1; OPRM1
232 ORF15_6_154255952_154259046_154307704_154312070_FF CNKSR3; IPCEF1; OPRM1
233 ORF15_6_40454949_40456428_40488042_40490875_RR LRFN2; rs148347825
234 ORF15_6_40454949_40456428_40488042_40490875_RR LRFN2; rs148347825
235 ORF150_1_221097555_221099745_221139551_221141679_RF rs12127195
236 ORF150_1_221097555_221099745_221139551_221141679_RF rs12127195
237 ORF151_11_106693665_106699542_106725393_106728226_FF GUCY1A2
238 ORF151_11_106693665_106699542_106725393_106728226_FF GUCY1A2
239 ORF152_13_60846170_60855031_60904843_60913572_FR TDRD3; rs7337573
240 ORF152_13_60846170_60855031_60904843_60913572_FR TDRD3; rs7337573
241 ORF154_14_38203591_38207960_38231669_38243239_RF CLEC14A; SSTR1; rs11622412
242 ORF154_14_38203591_38207960_38231669_38243239_RF CLEC14A; SSTR1; rs11622412
243 ORF155_16_15155840_15159398_15192529_15195024_RF PDXDC1; rs4003228
244 ORF155_16_15155840_15159398_15192529_15195024_RF PDXDC1; rs4003228
245 ORF155_7_117353457_117366529_117423152_117425489_FR ASZ1; WNT2; rs2188554; rs10249651
246 ORF155_7_117353457_117366529_117423152_117425489_FR ASZ1; WNT2; rs2188554; rs10249651
247 ORF156_1_116579148_116582139_116593950_116598324_RR CD58; IGSF3; rs724160030
248 ORF156_1_116579148_116582139_116593950_116598324_RR CD58; IGSF3; rs724160030
249 ORF156_2_138025661_138027521_138071201_138075562_FF HNMT
250 ORF156_2_138025661_138027521_138071201_138075562_FF HNMT
251 ORF156_20_46570710_46574158_46643075_46649811_FR SLC13A3; rs847058; rs6066043
252 ORF156_20_46570710_46574158_46643075_46649811_FR SLC13A3; rs847058; rs6066043
253 ORF156_5_127434266_127436041_127460011_127467027_RR MEGF10; rs387907071; rs387907072; rs199750143; rs794726678; rs989552169; rs794726677
254 ORF156_5_127434266_127436041_127460011_127467027_RR MEGF10; rs387907071; rs387907072; rs199750143; rs794726678; rs989552169; rs794726677
255 ORF158_2_102946170_102956566_102980783_102983000_FR TMEM182; rs12105421
256 ORF158_2_102946170_102956566_102980783_102983000_FR TMEM182; rs12105421
257 ORF158_7_92986182_92992000_93038794_93043170_RR rs12671937; rs739385
258 ORF158_7_92986182_92992000_93038794_93043170_RR rs12671937; rs739385
259 ORF159_11_84067130_84068735_84133096_84135736_FF DLG2; rs790356
260 ORF159_11_84067130_84068735_84133096_84135736_FF DLG2; rs790356
261 ORF16_1_35676542_35678104_35750293_35751842_RF C1orf216; CLSPN; PSMB2
262 ORF16_1_35676542_35678104_35750293_35751842_RF C1orf216; CLSPN; PSMB2
263 ORF16_1_59152323_59153557_59201894_59205260_RF rs12144699; rs6700125
264 ORF16_1_59152323_59153557_59201894_59205260_RF rs12144699; rs6700125
265 ORF16_10_82866083_82869829_82889344_82893485_RR NRG3; rs17101017; rs17685233
266 ORF16_10_82866083_82869829_82889344_82893485_RR NRG3; rs17101017; rs17685233
267 ORF16_15_42499291_42501030_42536264_42540825_FR HAUS2; LRRC57; SNAP23
268 ORF16_15_42499291_42501030_42536264_42540825_FR HAUS2; LRRC57; SNAP23
269 ORF16_2_209522065_209524486_209555031_209561510_FF MAP2; rs9288410
270 ORF16_2_209522065_209524486_209555031_209561510_FF MAP2; rs9288410
271 ORF16_2_46531602_46534170_46569163_46570628_FR ATP6V1E2; PIGF; RHOQ
272 ORF16_2_46531602_46534170_46569163_46570628_FR ATP6V1E2; PIGF; RHOQ
273 ORF16_4_37859966_37862832_37889307_37892348_FR GAFA3; PGM2; TBC1D1; rs17578878
274 ORF16_4_37859966_37862832_37889307_37892348_FR GAFA3; PGM2; TBC1D1; rs17578878
275 ORF16_5_124808480_124814364_124880024_124884131_FF ZNF608; rs4357030
276 ORF16_5_124808480_124814364_124880024_124884131_FF ZNF608; rs4357030
277 ORF16_5_74305244_74313564_74325511_74329920_RF rs167025; rs80337801
278 ORF16_5_74305244_74313564_74325511_74329920_RF rs167025; rs80337801
279 ORF16_6_137345960_137347521_137362789_137365756_RR OLIG3; rs13201877
280 ORF16_6_137345960_137347521_137362789_137365756_RR OLIG3; rs13201877
281 ORF160_3_67234045_67246290_67291641_67297587_FR KBTBD8; SUCLG2
282 ORF160_3_67234045_67246290_67291641_67297587_FR KBTBD8; SUCLG2
283 ORF161_3_192744752_192746116_192807100_192810430_FR FGF12; MB21D2
284 ORF161_3_192744752_192746116_192807100_192810430_FR FGF12; MB21D2
285 ORF161_4_59264971_59267015_59339329_59348337_RF NA
286 ORF161_4_59264971_59267015_59339329_59348337_RF NA
287 ORF162_X_39303922_39309694_39331263_39333882_FF rs5917854
288 ORF162_X_39303922_39309694_39331263_39333882_FF rs5917854
289 ORF163_2_209684451_209692640_209735707_209738646_FF MAP2; UNC80; rs146432517
290 ORF163_2_209684451_209692640_209735707_209738646_FF MAP2; UNC80; rs146432517
291 ORF164_15_58557606_58564146_58584664_58585981_FF LIPC; rs113298164; rs1365771; rs60439253; rs6494025; rs7178362
292 ORF164_15_58557606_58564146_58584664_58585981_FF LIPC; rs113298164; rs1365771; rs60439253; rs6494025; rs7178362
293 ORF165_13_97124956_97128666_97195242_97199543_RF MBNL2; OXGR1
294 ORF165_13_97124956_97128666_97195242_97199543_RF MBNL2; OXGR1
295 ORF165_5_159344811_159354581_159378555_159380399_FF rs953861; rs6556411; rs6556412; rs4379175; rs10045431
296 ORF165_5_159344811_159354581_159378555_159380399_FF rs953861; rs6556411; rs6556412; rs4379175; rs10045431
297 ORF169_7_93011591_93016612_93036188_93038794_RF rs12671937; rs739385
298 ORF169_7_93011591_93016612_93036188_93038794_RF rs12671937; rs739385
299 ORF17_1_69089823_69102269_69164723_69166979_RR rs9436866; rs10789285
300 ORF17_1_69089823_69102269_69164723_69166979_RR rs9436866; rs10789285
301 ORF17_1_76000194_76003911_76083373_76086337_FF ST6GALNAC3; rs12095069
302 ORF17_1_76000194_76003911_76083373_76086337_FF ST6GALNAC3; rs12095069
303 ORF17_12_75136236_75139196_75166435_75186315_RR CAPS2; KCNC2
304 ORF17_12_75136236_75139196_75166435_75186315_RR CAPS2; KCNC2
305 ORF17_13_33822756_33828516_33873349_33876786_RR RFC3; rs12429186
306 ORF17_13_33822756_33828516_33873349_33876786_RR RFC3; rs12429186
307 ORF17_19_46479838_46481514_46541191_46545048_FF PNMAL1; PNMAL2; PPP5D1
308 ORF17_19_46479838_46481514_46541191_46545048_FF PNMAL1; PNMAL2; PPP5D1
309 ORF17_2_5850709_5859559_5924503_5932342_RF rs16864170; rs10929925
310 ORF17_2_5850709_5859559_5924503_5932342_RF rs16864170; rs10929925
311 ORF17_22_25661627_25666380_25694410_25695479_FF ADRBK2; rs8142284; rs12158587
312 ORF17_22_25661627_25666380_25694410_25695479_FF ADRBK2; rs8142284; rs12158587
313 ORF17_4_125340607_125343598_125357325_125363715_RR FAT4; rs1039808
314 ORF17_4_125340607_125343598_125357325_125363715_RR FAT4; rs1039808
315 ORF17_5_74294290_74298111_74386498_74391810_RF rs80337801; rs12517545; rs167025
316 ORF17_5_74294290_74298111_74386498_74391810_RF rs80337801; rs12517545; rs167025
317 ORF17_6_482421_486539_555690_558488_FR EXOC2; rs116446171; rs950039; rs9392056; rs6918152; rs2476847; rs12210050
318 ORF17_6_482421_486539_555690_558488_FR EXOC2; rs116446171; rs950039; rs9392056; rs6918152; rs2476847; rs12210050
319 ORF17_8_10100695_10103743_10175271_10177408_FF MSRA; rs10087178; rs10107815; rs73191547; rs7012397
320 ORF17_8_10100695_10103743_10175271_10177408_FF MSRA; rs10087178; rs10107815; rs73191547; rs7012397
321 ORF17_8_21022651_21025530_21054445_21056962_RR rs500816; rs7015657
322 ORF17_8_21022651_21025530_21054445_21056962_RR rs500816; rs7015657
323 ORF173_2_172799773_172804834_172831811_172834823_FR RAPGEF4; rs733331
324 ORF173_2_172799773_172804834_172831811_172834823_FR RAPGEF4; rs733331
325 ORF174_1_66141924_66143825_66164982_66168816_RF PDE4B; rs490094
326 ORF174_1_66141924_66143825_66164982_66168816_RF PDE4B; rs490094
327 ORF174_12_96219857_96223649_96237099_96241349_RR ELK3; rs4762284
328 ORF174_12_96219857_96223649_96237099_96241349_RR ELK3; rs4762284
329 ORF174_13_97124956_97128666_97147277_97152656_RR MBNL2; OXGR1
330 ORF174_13_97124956_97128666_97147277_97152656_RR MBNL2; OXGR1
表3.c1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
221 NA NA NA
222 NA NA NA
223 60; 53; NA 1; 1; 1; 1; NA 0.22379944; 0.199487628; 0.261255041; 0.238249082; NA
224 60; 53; NA 1; 1; 1; 1; NA 0.22379944; 0.199487628; 0.261255041; 0.238249082; NA
225 175; NA 4; 4; NA 0.096861772; 0.075450093; NA
226 175; NA 4; 4; NA 0.096861772; 0.075450093; NA
227 30; NA 4; 5; NA 0.022454364; 0.006393518; NA
228 30; NA 4; 5; NA 0.022454364; 0.006393518; NA
229 48; 46; NA 1; 1; 1; 1; NA 0.288729231; 0.267628012; 0.299630226; 0.279547236; NA
230 48; 46; NA 1; 1; 1; 1; NA 0.288729231; 0.267628012; 0.299630226; 0.279547236; NA
231 163; 163; 140 4; 2; 4; 2; 4; 2 0.117375195; 0.022678142; 0.117375195; 0.022678142; 0.158806697; 0.045194146
232 163; 163; 140 4; 2; 4; 2; 4; 2 0.117375195; 0.022678142; 0.117375195; 0.022678142; 0.158806697; 0.045194146
233 45; NA 1; 1; NA 0.305019886; 0.285503815; NA
234 45; NA 1; 1; NA 0.305019886; 0.285503815; NA
235 NA NA NA
236 NA NA NA
237 36 1; 1 0.349116343; 0.336492635
238 36 1; 1 0.349116343; 0.336492635
239 1; NA 1; 1; NA 0.038988153; 0.042102538; NA
240 1; NA 1; 1; NA 0.038988153; 0.042102538; NA
241 43; 49; NA 1; 1; 1; 1; NA 0.315614698; 0.297350686; 0.283240383; 0.261686551; NA
242 43; 49; NA 1; 1; 1; 1; NA 0.315614698; 0.297350686; 0.283240383; 0.261686551; NA
243 38; NA 2; 1; NA 0.255573168; 0.325888812; NA
244 38; NA 2; 1; NA 0.255573168; 0.325888812; NA
245 23; 23; NA 2; 2; 2; 2; NA 0.166907425; 0.181828486; 0.166907425; 0.181828486; NA
246 23; 23; NA 2; 2; 2; 2; NA 0.166907425; 0.181828486; 0.166907425; 0.181828486; NA
247 22; 23; NA 1; 1; 1; 1; NA 0.372324987; 0.375573766; 0.374075448; 0.376115439; NA
248 22; 23; NA 1; 1; 1; 1; NA 0.372324987; 0.375573766; 0.374075448; 0.376115439; NA
249 12 1; 1 0.302214299; 0.314913912
250 12 1; 1 0.302214299; 0.314913912
251 117; NA 2; 3; NA 0.106169317; 0.143969124; NA
252 117; NA 2; 3; NA 0.106169317; 0.143969124; NA
253 26; NA 3; 3; NA 0.061689421; 0.072111; NA
254 26; NA 3; 3; NA 0.061689421; 0.072111; NA
255 27; NA 2; 3; NA 0.197546356; 0.077717327; NA
256 27; NA 2; 3; NA 0.197546356; 0.077717327; NA
257 NA NA NA
258 NA NA NA
259 22; NA 3; 3; NA 0.042821316; 0.050708849; NA
260 22; NA 3; 3; NA 0.042821316; 0.050708849; NA
261 50; 83; 12 1; 1; 1; 1; 1; 1 0.277739605; 0.255769837; 0.123780263; 0.102353336; 0.302214299; 0.314913912
262 50; 83; 12 1; 1; 1; 1; 1; 1 0.277739605; 0.255769837; 0.123780263; 0.102353336; 0.302214299; 0.314913912
263 NA NA NA
264 NA NA NA
265 22; NA 1; 1; NA 0.372324987; 0.375573766; NA
266 22; NA 1; 1; NA 0.372324987; 0.375573766; NA
267 41; 29; 26 1; 1; 1; 1; 1; 1 0.325868449; 0.309016356; 0.371537436; 0.366349054; 0.375314357; 0.373699919
268 41; 29; 26 1; 1; 1; 1; 1; 1 0.325868449; 0.309016356; 0.371537436; 0.366349054; 0.375314357; 0.373699919
269 60; NA 5; 7; NA 0.05512946; 0.009185497; NA
270 60; NA 5; 7; NA 0.05512946; 0.009185497; NA
271 33; 25; 37 1; 1; 1; 1; 1; 1 0.360592644; 0.35096223; 0.375519541; 0.375121431; 0.34481748; 0.331269672
272 33; 25; 37 1; 1; 1; 1; 1; 1 0.360592644; 0.35096223; 0.375519541; 0.375121431; 0.34481748; 0.331269672
273 37; 37; 40; NA 5; 8; 5; 8; 2; 3; NA 0.010942367; 0.000107113; 0.010942367; 0.000107113; 0.261899069; 0.150241062; NA
274 37; 37; 40; NA 5; 8; 5; 8; 2; 3; NA 0.010942367; 0.000107113; 0.010942367; 0.000107113; 0.261899069; 0.150241062; NA
275 48; NA 1; 1; NA 0.288729231; 0.267628012; NA
276 48; NA 1; 1; NA 0.288729231; 0.267628012; NA
277 NA NA NA
278 NA NA NA
279 70; NA 1; 1; NA 0.175291065; 0.151233777; NA
280 70; NA 1; 1; NA 0.175291065; 0.151233777; NA
281 22; 8 1; 1; 1; 1 0.372324987; 0.375573766; 0.236185646; 0.249326315
282 22; 8 1; 1; 1; 1 0.372324987; 0.375573766; 0.236185646; 0.249326315
283 22; 22 1; 1; 1; 1 0.372324987; 0.375573766; 0.372324987; 0.375573766
284 22; 22 1; 1; 1; 1 0.372324987; 0.375573766; 0.372324987; 0.375573766
285 NA NA NA
286 NA NA NA
287 NA NA NA
288 NA NA NA
289 60; 35; NA 5; 7; 1; 1; NA 0.05512946; 0.009185497; 0.353195365; 0.341533433; NA
290 60; 35; NA 5; 7; 1; 1; NA 0.05512946; 0.009185497; 0.353195365; 0.341533433; NA
291 12; NA 1; 1; NA 0.302214299; 0.314913912; NA
292 12; NA 1; 1; NA 0.302214299; 0.314913912; NA
293 62; 12 2; 2; 2; 2 0.264714788; 0.254031269; 0.067384485; 0.076075379
294 62; 12 2; 2; 2; 2 0.264714788; 0.254031269; 0.067384485; 0.076075379
295 NA NA NA
296 NA NA NA
297 NA NA NA
298 NA NA NA
299 NA NA NA
300 NA NA NA
301 45; NA 5; 5; NA 0.022343156; 0.028833151; NA
302 45; NA 5; 5; NA 0.022343156; 0.028833151; NA
303 13; 13 4; 4; 4; 4 0.001148684; 0.001517434; 0.001148684; 0.001517434
304 13; 13 4; 4; 4; 4 0.001148684; 0.001517434; 0.001148684; 0.001517434
305 17; NA 1; 2; NA 0.350975055; 0.126473611; NA
306 17; NA 1; 2; NA 0.350975055; 0.126473611; NA
307 28; 32; 32 3; 4; 3; 4; 3; 4 0.071800115; 0.02285211; 0.09275567; 0.033810966; 0.09275567; 0.033810966
308 28; 32; 32 3; 4; 3; 4; 3; 4 0.071800115; 0.02285211; 0.09275567; 0.033810966; 0.09275567; 0.033810966
309 NA NA NA
310 NA NA NA
311 110; NA 1; 4; NA 0.055848211; 0.190296804; NA
312 110; NA 1; 4; NA 0.055848211; 0.190296804; NA
313 19; NA 3; 4; NA 0.030348034; 0.006361707; NA
314 19; NA 3; 4; NA 0.030348034; 0.006361707; NA
315 NA NA NA
316 NA NA NA
317 25; NA 1; 1; NA 0.375519541; 0.375121431; NA
318 25; NA 1; 1; NA 0.375519541; 0.375121431; NA
319 115; NA 4; 4; NA 0.193790369; 0.18374459; NA
320 115; NA 4; 4; NA 0.193790369; 0.18374459; NA
321 NA NA NA
322 NA NA NA
323 30; NA 1; 1; NA 0.36936157; 0.363021342; NA
324 30; NA 1; 1; NA 0.36936157; 0.363021342; NA
325 17; NA 3; 2; NA 0.023054538; 0.126473611; NA
326 17; NA 3; 2; NA 0.023054538; 0.126473611; NA
327 13; NA 2; 3; NA 0.076537269; 0.013853987; NA
328 13; NA 2; 3; NA 0.076537269; 0.013853987; NA
329 62; 12 2; 2; 2; 2 0.264714788; 0.254031269; 0.067384485; 0.076075379
330 62; 12 2; 2; 2; 2 0.264714788; 0.254031269; 0.067384485; 0.076075379
表3.c2
   FDR_HyperG Percent_Sig logFC AveExpr
221 NA NA -0.726698111 -0.726698111
222 NA NA -0.726057795 -0.726057795
223 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.67; 1.67; 1.89; 1.89; NA -0.972967521 -0.972967521
224 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.67; 1.67; 1.89; 1.89; NA -0.970348937 -0.970348937
225 0.375519541; 0.376115439; NA 2.29; 2.29; NA -0.759303568 -0.759303568
226 0.375519541; 0.376115439; NA 2.29; 2.29; NA -0.714670963 -0.714670963
227 0.375519541; 0.217379602; NA 13.33; 16.67; NA -0.845291244 -0.845291244
228 0.375519541; 0.217379602; NA 13.33; 16.67; NA -0.737301237 -0.737301237
229 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.08; 2.08; 2.17; 2.17; NA -0.808158746 -0.808158746
230 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.08; 2.08; 2.17; 2.17; NA -0.771402868 -0.771402868
231 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.45; 1.23; 2.45; 1.23; 2.86; 1.43 -0.973554656 -0.973554656
232 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.45; 1.23; 2.45; 1.23; 2.86; 1.43 -0.744378809 -0.744378809
233 0.375519541; 0.376115439; NA 2.22; 2.22; NA -0.750559533 -0.750559533
234 0.375519541; 0.376115439; NA 2.22; 2.22; NA -0.747547131 -0.747547131
235 NA NA -1.515895749 -1.515895749
236 NA NA -1.463401445 -1.463401445
237 0.375519541; 0.376115439 2.78; 2.78 -0.969964962 -0.969964962
238 0.375519541; 0.376115439 2.78; 2.78 -0.85652158 -0.85652158
239 0.375519541; 0.376115439; NA 100; 100; NA -0.831727698 -0.831727698
240 0.375519541; 0.376115439; NA 100; 100; NA -0.760675915 -0.760675915
241 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.33; 2.33; 2.04; 2.04; NA -1.07314694 -1.07314694
242 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.33; 2.33; 2.04; 2.04; NA -0.941218749 -0.941218749
243 0.375519541; 0.376115439; NA 5.26; 2.63; NA -0.759263952 -0.759263952
244 0.375519541; 0.376115439; NA 5.26; 2.63; NA -0.722790727 -0.722790727
245 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 8.7; 8.7; 8.7; 8.7; NA -0.790564324 -0.790564324
246 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 8.7; 8.7; 8.7; 8.7; NA -0.775827182 -0.775827182
247 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4.55; 4.55; 4.35; 4.35; NA -0.899938733 -0.899938733
248 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4.55; 4.55; 4.35; 4.35; NA -0.896218026 -0.896218026
249 0.375519541; 0.376115439 8.33; 8.33 -1.179694021 -1.179694021
250 0.375519541; 0.376115439 8.33; 8.33 -0.97212929 -0.97212929
251 0.375519541; 0.376115439; NA 1.71; 2.56; NA -0.78521903 -0.78521903
252 0.375519541; 0.376115439; NA 1.71; 2.56; NA -0.743346757 -0.743346757
253 0.375519541; 0.376115439; NA 11.54; 11.54; NA -0.971200525 -0.971200525
254 0.375519541; 0.376115439; NA 11.54; 11.54; NA -0.831127148 -0.831127148
255 0.375519541; 0.376115439; NA 7.41; 11.11; NA -1.370319868 -1.370319868
256 0.375519541; 0.376115439; NA 7.41; 11.11; NA -1.3514784 -1.3514784
257 NA NA -0.778719679 -0.778719679
258 NA NA -0.691828819 -0.691828819
259 0.375519541; 0.376115439; NA 13.64; 13.64; NA -0.909665705 -0.909665705
260 0.375519541; 0.376115439; NA 13.64; 13.64; NA -0.796673674 -0.796673674
261 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2; 2; 1.2; 1.2; 8.33; 8.33 -0.734466175 -0.734466175
262 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2; 2; 1.2; 1.2; 8.33; 8.33 -0.706471144 -0.706471144
263 NA NA -0.907101553 -0.907101553
264 NA NA -0.769675227 -0.769675227
265 0.375519541; 0.376115439; NA 4.55; 4.55; NA -0.816029888 -0.816029888
266 0.375519541; 0.376115439; NA 4.55; 4.55; NA -0.712243866 -0.712243866
267 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.44; 2.44; 3.45; 3.45; 3.85; 3.85 -0.957971684 -0.957971684
268 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.44; 2.44; 3.45; 3.45; 3.85; 3.85 -0.858499735 -0.858499735
269 0.375519541; 0.275564898; NA 8.33; 11.67; NA -0.798611058 -0.798611058
270 0.375519541; 0.275564898; NA 8.33; 11.67; NA -0.776769251 -0.776769251
271 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.03; 3.03; 4; 4; 2.7; 2.7 -0.897770765 -0.897770765
272 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.03; 3.03; 4; 4; 2.7; 2.7 -0.764254297 -0.764254297
273 0.357678624; 0.013656923; 0.357678624; 0.013656923; 0.375519541; 0.376115439; NA 13.51; 21.62; 13.51; 21.62; 5; 7.5; NA -1.836212004 -1.836212004
274 0.357678624; 0.013656923; 0.357678624; 0.013656923; 0.375519541; 0.376115439; NA 13.51; 21.62; 13.51; 21.62; 5; 7.5; NA -1.603541061 -1.603541061
275 0.375519541; 0.376115439; NA 2.08; 2.08; NA -1.468540904 -1.468540904
276 0.375519541; 0.376115439; NA 2.08; 2.08; NA -1.070675584 -1.070675584
277 NA NA -1.461923568 -1.461923568
278 NA NA -1.403737685 -1.403737685
279 0.375519541; 0.376115439; NA 1.43; 1.43; NA -1.002714272 -1.002714272
280 0.375519541; 0.376115439; NA 1.43; 1.43; NA -0.938173563 -0.938173563
281 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 12.5; 12.5 -0.711833222 -0.711833222
282 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 12.5; 12.5 -0.672072705 -0.672072705
283 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 4.55; 4.55 -0.846490154 -0.846490154
284 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.55; 4.55; 4.55; 4.55 -0.774817701 -0.774817701
285 NA NA -1.003303154 -1.003303154
286 NA NA -0.715984515 -0.715984515
287 NA NA -0.82136057 -0.82136057
288 NA NA -0.746382779 -0.746382779
289 0.375519541; 0.275564898; 0.375519541; 0.376115439; NA 8.33; 11.67; 2.86; 2.86; NA -0.83262013 -0.83262013
290 0.375519541; 0.275564898; 0.375519541; 0.376115439; NA 8.33; 11.67; 2.86; 2.86; NA -0.707142612 -0.707142612
291 0.375519541; 0.376115439; NA 8.33; 8.33; NA -0.864175665 -0.864175665
292 0.375519541; 0.376115439; NA 8.33; 8.33; NA -0.725027539 -0.725027539
293 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.23; 3.23; 16.67; 16.67 -0.727163704 -0.727163704
294 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.23; 3.23; 16.67; 16.67 -0.701856007 -0.701856007
295 NA NA -1.215854511 -1.215854511
296 NA NA -1.117529237 -1.117529237
297 NA NA -0.877425807 -0.877425807
298 NA NA -0.740291846 -0.740291846
299 NA NA -1.056331907 -1.056331907
300 NA NA -0.93331802 -0.93331802
301 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.960387084 -0.960387084
302 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.739716304 -0.739716304
303 0.069549998; 0.082088441; 0.069549998; 0.082088441 30.77; 30.77; 30.77; 30.77 -0.83350941 -0.83350941
304 0.069549998; 0.082088441; 0.069549998; 0.082088441 30.77; 30.77; 30.77; 30.77 -0.817702142 -0.817702142
305 0.375519541; 0.376115439; NA 5.88; 11.76; NA -1.040949661 -1.040949661
306 0.375519541; 0.376115439; NA 5.88; 11.76; NA -0.969050047 -0.969050047
307 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.71; 14.29; 9.38; 12.5; 9.38; 12.5 -1.005430659 -1.005430659
308 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.71; 14.29; 9.38; 12.5; 9.38; 12.5 -0.864780498 -0.864780498
309 NA NA -1.070122518 -1.070122518
310 NA NA -0.968555139 -0.968555139
311 0.375519541; 0.376115439; NA 0.91; 3.64; NA -1.040267643 -1.040267643
312 0.375519541; 0.376115439; NA 0.91; 3.64; NA -0.829513074 -0.829513074
313 0.375519541; 0.217379602; NA 15.79; 21.05; NA -0.882508243 -0.882508243
314 0.375519541; 0.217379602; NA 15.79; 21.05; NA -0.707959382 -0.707959382
315 NA NA -0.989337766 -0.989337766
316 NA NA -0.835094075 -0.835094075
317 0.375519541; 0.376115439; NA 4; 4; NA -1.085573197 -1.085573197
318 0.375519541; 0.376115439; NA 4; 4; NA -0.672666103 -0.672666103
319 0.375519541; 0.376115439; NA 3.48; 3.48; NA -1.39412829 -1.39412829
320 0.375519541; 0.376115439; NA 3.48; 3.48; NA -1.358173278 -1.358173278
321 NA NA -0.846081071 -0.846081071
322 NA NA -0.750491323 -0.750491323
323 0.375519541; 0.376115439; NA 3.33; 3.33; NA -0.947673241 -0.947673241
324 0.375519541; 0.376115439; NA 3.33; 3.33; NA -0.783071343 -0.783071343
325 0.375519541; 0.376115439; NA 17.65; 11.76; NA -1.383777574 -1.383777574
326 0.375519541; 0.376115439; NA 17.65; 11.76; NA -0.941911055 -0.941911055
327 0.375519541; 0.376115439; NA 15.38; 23.08; NA -0.780409932 -0.780409932
328 0.375519541; 0.376115439; NA 15.38; 23.08; NA -0.775260334 -0.775260334
329 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.23; 3.23; 16.67; 16.67 -0.787045617 -0.787045617
330 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.23; 3.23; 16.67; 16.67 -0.71359646 -0.71359646
表3.c3
   t P值 adj.P.Val B FC FC_1 LS
221 -15.09502527 0.00000000387 0.00000354 11.49687023 0.604285357 -1.654847313 -1
222 -10.24932946 0.000000278 0.0000182 7.309460357 0.604553619 -1.654113 -1
223 -4.796617416 0.000442557 0.004121332 -0.183920012 0.509457067 -1.962873938 -1
224 -14.67225906 0.00000000510 0.00000207 11.28105246 0.510382604 -1.959314427 -1
225 -4.305065536 0.001035003 0.007382021 -1.052020008 0.59078145 -1.692673323 -1
226 -6.554004906 0.0000273 0.000337583 2.597998805 0.60934409 -1.641108885 -1
227 -10.91571236 0.00000014 0.000012 8.004066765 0.556598434 -1.796627403 -1
228 -9.658227518 0.000000544 0.0000513 6.668613592 0.599860426 -1.667054461 -1
229 -5.324291463 0.000184319 0.002243312 0.714501349 0.571110278 -1.750975316 -1
230 -4.848291313 0.000401145 0.002265984 -0.175440037 0.585847523 -1.706928784 -1
231 -5.838884332 0.0000815 0.001272083 1.553702329 0.509249775 -1.963672933 -1
232 -8.479699536 0.00000208 0.0000633 5.252788304 0.596924838 -1.675252789 -1
233 -5.05278884 0.000287874 0.003050707 0.256863106 0.594372992 -1.682445221 -1
234 -5.130176991 0.000250236 0.001602292 0.310504266 0.595615362 -1.678935877 -1
235 -12.39535418 0.0000000342 0.00000549 9.413438414 0.349679288 -2.859763314 -1
236 -14.21195153 0.00000000767 0.00000485 10.85135629 0.36263713 -2.757577525 -1
237 -8.089141457 0.00000339 0.0000858 4.752323254 0.510518461 -1.958793023 -1
238 -8.257617798 0.00000281 0.000142122 5.004014461 0.552282539 -1.810667421 -1
239 -11.35524954 0.0000000906 0.00000926 8.441011886 0.561855989 -1.779815503 -1
240 -6.172971569 0.0000489 0.000899687 2.078339821 0.590219743 -1.694284225 -1
241 -8.960821697 0.00000117 0.000044 5.844968081 0.47528114 -2.104017844 -1
242 -7.193624257 0.0000113 0.000341309 3.583441139 0.520792743 -1.920149644 -1
243 -9.908768536 0.0000004 0.0000225 6.938595898 0.590797673 -1.692626844 -1
244 -8.184308062 0.00000308 0.000150742 4.910698978 0.605924217 -1.650371402 -1
245 -6.662779622 0.0000233 0.000305263 2.761039155 0.578117911 -1.729750939 -1
246 -9.077710492 0.00000105 0.0000764 6.004990049 0.584053656 -1.712171458 -1
247 -8.234686551 0.00000282 0.0000764 4.940953894 0.535909489 -1.865986738 -1
248 -7.256379754 0.0000104 0.000323016 3.671302969 0.537293382 -1.861180564 -1
249 -8.472209255 0.0000021 0.0000636 5.243359837 0.441445114 -2.265287279 -1
250 -6.303172515 0.0000402 0.000790002 2.278482958 0.509753157 -1.961733805 -1
251 -6.921533194 0.0000161 0.000239242 3.142313066 0.580263855 -1.723353939 -1
252 -7.058019872 0.0000136 0.000386075 3.391774667 0.597352009 -1.674054802 -1
253 -7.795288638 0.00000494 0.000109876 4.363578625 0.510081427 -1.960471304 -1
254 -6.513057223 0.0000295 0.000644848 2.59604273 0.562089921 -1.779074774 -1
255 -11.37148718 0.0000000925 0.0000177 8.435677674 0.386805478 -2.585278794 -1
256 -8.586000536 0.00000183 0.0000583 5.385894109 0.391890254 -2.551734802 -1
257 -5.792701812 0.0000862 0.00074495 1.410356705 0.582883845 -1.71560768 -1
258 -9.104696077 0.00000102 0.0000749 6.036636344 0.619068596 -1.615329879 -1
259 -8.45165409 0.00000216 0.0000647 5.217452206 0.532308421 -1.878610144 -1
260 -6.054564483 0.0000585 0.001016568 1.894224705 0.575674944 -1.73709141 -1
261 -5.51188889 0.000136271 0.00180854 1.024769019 0.60104038 -1.663781724 -1
262 -6.501548418 0.0000295 0.000355217 2.518783878 0.612817268 -1.631807803 -1
263 -9.754862412 0.000000474 0.0000251 6.767298674 0.533255353 -1.875274191 -1
264 -7.338035998 0.00000928 0.00030197 3.784839448 0.586549501 -1.704885944 -1
265 -3.314059132 0.006189686 0.017780919 -2.959508843 0.568002865 -1.7605545 -1
266 -4.2954428 0.001052681 0.00747151 -1.069277796 0.610370074 -1.638350311 -1
267 -7.059717062 0.0000133 0.000209886 3.342182682 0.514780145 -1.942576864 -1
268 -12.47149186 0.0000000333 0.0000102 9.438927188 0.551525794 -1.813151825 -1
269 -7.618329677 0.00000624 0.00012779 4.12426192 0.574902393 -1.739425703 -1
270 -8.605887581 0.00000183 0.000108855 5.438567497 0.583672398 -1.713289859 -1
271 -12.97814091 0.0000000204 0.00000415 9.923470568 0.536715417 -1.863184787 -1
272 -10.07716341 0.000000345 0.0000388 7.126039298 0.588757608 -1.698491852 -1
273 -15.83292475 0.00000000213 0.00000133 12.11652349 0.280056146 -3.570712564 -1
274 -16.38350644 0.00000000152 0.00000227 12.3642491 0.329068295 -3.038882853 -1
275 -11.59799178 0.0000000717 0.00000816 8.675486503 0.36134757 -2.76741864 -1
276 -5.280146015 0.000198038 0.002356397 0.640776841 0.476096001 -2.100416719 -1
277 -10.63452615 0.000000186 0.0000143 7.715837877 0.363008801 -2.754754147 -1
278 -11.83049363 0.0000000598 0.0000136 8.865717964 0.377948696 -2.645861757 -1
279 -9.372973884 0.000000726 0.0000329 6.331952557 0.499060189 -2.003766321 -1
280 -6.77459111 0.0000203 0.000504023 2.983065863 0.521893174 -1.916100938 -1
281 -6.485153998 0.0000302 0.000360864 2.493947705 0.610543832 -1.637884042 -1
282 -7.023767292 0.0000143 0.000398328 3.342966879 0.627604367 -1.593360488 -1
283 -5.563719206 0.000123743 0.000961403 1.037121649 0.556136082 -1.798121059 -1
284 -9.298866893 0.000000814 0.0000651 6.262016494 0.584462472 -1.710973839 -1
285 -5.704817415 0.000099 0.000821495 1.267980575 0.498856524 -2.00458439 -1
286 -3.583083655 0.003791178 0.018250289 -2.36730167 0.608789543 -1.642603771 -1
287 -6.331086712 0.0000386 0.000767676 2.321077965 0.565907997 -1.767071689 -1
288 -6.295755245 0.00004 0.000436154 2.204291448 0.596096258 -1.67758141 -1
289 -13.03241832 0.0000000195 0.00000406 9.969780502 0.56150854 -1.780916814 -1
290 -10.13766846 0.000000323 0.0000376 7.190678617 0.612532114 -1.632567465 -1
291 -5.152045201 0.000241351 0.001559694 0.347767929 0.549360214 -1.820299277 -1
292 -6.515394415 0.0000294 0.000643302 2.599543863 0.604985496 -1.652932188 -1
293 -8.172223732 0.00000305 0.0000804 4.86031352 0.604090371 -1.655381459 -1
294 -6.309718116 0.0000399 0.000784214 2.288481009 0.614780791 -1.62659604 -1
295 -8.842688633 0.00000134 0.0000482 5.701981752 0.430518008 -2.32278321 -1
296 -10.99328362 0.000000134 0.0000221 8.068314954 0.460882458 -2.169750622 -1
297 -7.095796343 0.0000127 0.000202991 3.393943275 0.544337824 -1.837094457 -1
298 -7.992355313 0.00000393 0.000175109 4.663255461 0.598618244 -1.670513737 -1
299 -12.1895176 0.0000000413 0.00000598 9.227517438 0.480853089 -2.079637258 -1
300 -10.17139509 0.000000312 0.0000369 7.226556964 0.52365262 -1.909662938 -1
301 -10.09622433 0.000000327 0.00002 7.144106153 0.513919007 -1.945831903 -1
302 -11.09860644 0.000000121 0.0000206 8.171836585 0.598857102 -1.669847442 -1
303 -8.411534972 0.00000227 0.0000667 5.166743952 0.561162532 -1.782014912 -1
304 -6.049342373 0.000059 0.001021499 1.886058513 0.567344864 -1.762596374 -1
305 -8.464436493 0.00000212 0.0000641 5.233568882 0.486007452 -2.05758162 -1
306 -7.634401178 0.00000625 0.000233236 4.189529526 0.51084232 -1.957551207 -1
307 -8.008967166 0.00000385 0.000173339 4.684849003 0.498121415 -2.00754268 -1
308 -6.246490908 0.0000431 0.000458332 2.128122037 0.549129949 -1.821062576 -1
309 -10.43651407 0.000000228 0.0000161 7.508636121 0.47627855 -2.099611664 -1
310 -10.75242162 0.000000171 0.0000257 7.827948595 0.511017591 -1.956879796 -1
311 -11.69251984 0.0000000655 0.00000769 8.765520045 0.486237261 -2.056609151 -1
312 -8.844888887 0.00000138 0.0000906 5.728620268 0.562719134 -1.777085475 -1
313 -7.834384291 0.0000047 0.000106426 4.415917682 0.542423563 -1.843577727 -1
314 -7.944981466 0.00000417 0.000181804 4.601486399 0.612185432 -1.633491992 -1
315 -8.022939853 0.00000369 0.0000907 4.665673227 0.503708937 -1.985273491 -1
316 -9.058879802 0.00000107 0.0000771 5.9828599 0.560546486 -1.783973364 -1
317 -7.178072619 0.0000113 0.000188258 3.511326602 0.471205016 -2.122218493 -1
318 -5.784807352 0.0000886 0.00134607 1.467280723 0.627346278 -1.594015992 -1
319 -16.56621545 0.00000000134 0.00000216 12.48065645 0.38047451 -2.628296962 -1
320 -20.48448052 0.000000000108 0.00000039 14.86398276 0.390075886 -2.563603736 -1
321 -9.460539812 0.000000658 0.0000307 6.433098271 0.556293799 -1.797611266 -1
322 -12.12127333 0.0000000457 0.000012 9.129577314 0.594401094 -1.682365678 -1
323 -7.915940352 0.00000423 0.0000992 4.524485486 0.518467966 -1.928759471 -1
324 -9.257002532 0.000000854 0.0000673 6.213766102 0.581128316 -1.720790354 -1
325 -10.91294799 0.00000014 0.000012 8.001266796 0.383214067 -2.609507547 -1
326 -5.834260864 0.000082 0.001278013 1.5463298 0.52054289 -1.921071286 -1
327 -8.463521893 0.00000212 0.0000642 5.232416344 0.582201341 -1.717618853 -1
328 -6.017103925 0.0000619 0.001056554 1.835558518 0.584283181 -1.711498863 -1
329 -12.98333109 0.0000000212 0.00000816 9.875172609 0.579529651 -1.725537249 -1
330 -10.28382014 0.000000268 0.0000179 7.346405373 0.609798091 -1.639887061 -1
表3.c4
      探針序列 探針位置
偵測到之環 60 mer Chr
221 mAD CTAAGAACTTGACAATTTCATAAGGCTTTCGATGGGCCTAGCTTGGCTCTAAGCACTTTA 16
222 sAD CTAAGAACTTGACAATTTCATAAGGCTTTCGATGGGCCTAGCTTGGCTCTAAGCACTTTA 16
223 mAD AGCAAAAAGTGAAGACTGCTTGACTTTTTCGAAAAAAAAAAAAAGGAAAAATATCATGTC 2
224 sAD AGCAAAAAGTGAAGACTGCTTGACTTTTTCGAAAAAAAAAAAAAGGAAAAATATCATGTC 2
225 mAD GTTAAGTGGTGTACTTTTTGAAAATCCATCGAACAGAAATTCCTTTTCATATTTTCAAAA 20
226 sAD GTTAAGTGGTGTACTTTTTGAAAATCCATCGAACAGAAATTCCTTTTCATATTTTCAAAA 20
227 sAD GGAATGAATAATAAATTTCCTGTCATTGTCGAGAAAATATCTTGTCTGGGCCAGGCCTCT 3
228 mAD GGAATGAATAATAAATTTCCTGTCATTGTCGAGAAAATATCTTGTCTGGGCCAGGCCTCT 3
229 mAD TGTTTTAGTGCCTTCAGCACATTTATTTTCGATTTTAGCCCCATAAAACTATTTTCAGAT 3
230 sAD TGTTTTAGTGCCTTCAGCACATTTATTTTCGATTTTAGCCCCATAAAACTATTTTCAGAT 3
231 mAD GACAGATGTCTGCAAAGCCATCTACTGCTCGATGGACAAAGATTGATTGCATATCTTGGC 6
232 sAD GACAGATGTCTGCAAAGCCATCTACTGCTCGATGGACAAAGATTGATTGCATATCTTGGC 6
233 mAD ACCTTTCAAAAAATTTCTGGCTTATACATCGAAAAGGAGAGGGAATATTTTCTTTTGTTG 6
234 sAD ACCTTTCAAAAAATTTCTGGCTTATACATCGAAAAGGAGAGGGAATATTTTCTTTTGTTG 6
235 sAD GATGAAATGATTTTGCTATTGTCATACATCGATTTTTTTTTCTTTAGTAACAGAAAAAAT 1
236 mAD GATGAAATGATTTTGCTATTGTCATACATCGATTTTTTTTTCTTTAGTAACAGAAAAAAT 1
237 sAD CAGATGTCTCCCATATAAATAGGAATTATCGAATAGGAAATTGTTAGGTAATTAAGGTAG 11
238 mAD CAGATGTCTCCCATATAAATAGGAATTATCGAATAGGAAATTGTTAGGTAATTAAGGTAG 11
239 sAD GTGATAATCCTATTTGTAGTATAGATTATCGATAGATGCAGAAAAGGTCTTCAATAAAAT 13
240 mAD GTGATAATCCTATTTGTAGTATAGATTATCGATAGATGCAGAAAAGGTCTTCAATAAAAT 13
241 sAD AGGAATTAAAACTGTTGAAACTTTAGTCTCGAGACAATAGTTTTAAACTAATGCATCCAT 14
242 mAD AGGAATTAAAACTGTTGAAACTTTAGTCTCGAGACAATAGTTTTAAACTAATGCATCCAT 14
243 sAD ATTATAACATCTATAAAGAAAAATACCCTCGAAAAAAAAAAAATGGAAAAAAGAAAAAAA 16
244 mAD ATTATAACATCTATAAAGAAAAATACCCTCGAAAAAAAAAAAATGGAAAAAAGAAAAAAA 16
245 sAD ATAAAGAGCTCGGAAGTGAGCTCTTTAGTCGAATGACAAGCAGTGAGCTAAAATAAAGGG 7
246 mAD ATAAAGAGCTCGGAAGTGAGCTCTTTAGTCGAATGACAAGCAGTGAGCTAAAATAAAGGG 7
247 sAD AACATACCATATAATCTTTATAATAAACTCGAATGACATTCATATGGGCAAAAATTATGC 1
248 mAD AACATACCATATAATCTTTATAATAAACTCGAATGACATTCATATGGGCAAAAATTATGC 1
249 sAD TATCTTCTCTTCTTTCTCCATGAAAAAATCGATGAGGGGATATTTATTTGTTTTGTAACC 2
250 mAD TATCTTCTCTTCTTTCTCCATGAAAAAATCGATGAGGGGATATTTATTTGTTTTGTAACC 2
251 sAD GTAGCTGATTCAGTGGTGTTTATAAAGATCGAGACATACTTATGAGCACCTACTATGTGC 20
252 mAD GTAGCTGATTCAGTGGTGTTTATAAAGATCGAGACATACTTATGAGCACCTACTATGTGC 20
253 sAD CTTTAAGAGTCGTTTCTGGCAATAAAAATCGAATTTAATTTGACATTGATGTCACTCTTC 5
254 mAD CTTTAAGAGTCGTTTCTGGCAATAAAAATCGAATTTAATTTGACATTGATGTCACTCTTC 5
255 mAD TTCTCTTCTTTATTGCATTAATCTGGTTTCGATTTTCTCTTCTCTTTATAAAGGTTTTTT 2
256 sAD TTCTCTTCTTTATTGCATTAATCTGGTTTCGATTTTCTCTTCTCTTTATAAAGGTTTTTT 2
257 sAD ATTATTGCTGTTATTGTTATTCTTGCTATCGATGGAACAGAAAAAGAATGCAAAGAGACA 7
258 mAD ATTATTGCTGTTATTGTTATTCTTGCTATCGATGGAACAGAAAAAGAATGCAAAGAGACA 7
259 sAD CTCATTATACTGAGTTTATTTGTTTTATTCGACCTCTCACTGAAGCTTCCAGCTCATTTC 11
260 mAD CTCATTATACTGAGTTTATTTGTTTTATTCGACCTCTCACTGAAGCTTCCAGCTCATTTC 11
261 mAD ACCTATATTAAAGAAAAAGAGAAACGACTCGACTCTGTCTCAAAAAAATAAATAAAATAA 1
262 sAD ACCTATATTAAAGAAAAAGAGAAACGACTCGACTCTGTCTCAAAAAAATAAATAAAATAA 1
263 sAD CAGAAGGATCTCATCATTTAAAAAAATCTCGAAAAGCTTTTCTACCACTTCCCAGTAAAT 1
264 mAD CAGAAGGATCTCATCATTTAAAAAAATCTCGAAAAGCTTTTCTACCACTTCCCAGTAAAT 1
265 sAD TGTTCTTTCTTCATTTAATGTATAACCATCGACTTCAGTAACTGAAAAGATGTTTTGAAC 10
266 mAD TGTTCTTTCTTCATTTAATGTATAACCATCGACTTCAGTAACTGAAAAGATGTTTTGAAC 10
267 sAD GACAGTGTTTTGGAAATTGAAATTACTTTCGATGTAGGGTTGCTACAAACTGTCTATTTG 15
268 mAD GACAGTGTTTTGGAAATTGAAATTACTTTCGATGTAGGGTTGCTACAAACTGTCTATTTG 15
269 sAD CTTTATGATAATTGCTATGTTAGTAGCCTCGAGACTCAGAGAGGTTAAATAACTTCTCCA 2
270 mAD CTTTATGATAATTGCTATGTTAGTAGCCTCGAGACTCAGAGAGGTTAAATAACTTCTCCA 2
271 sAD GCCTTCAAATCATCACCGTTAATCCTTTTCGAAACACTTGACCAGCTCTCTCATTTATCT 2
272 mAD GCCTTCAAATCATCACCGTTAATCCTTTTCGAAACACTTGACCAGCTCTCTCATTTATCT 2
273 sAD CCTACCAGAACTCTTAAATCTATAATATTCGACTAACTCCTCCGTAAAGAATAGCTACCA 4
274 mAD CCTACCAGAACTCTTAAATCTATAATATTCGACTAACTCCTCCGTAAAGAATAGCTACCA 4
275 sAD TAAAGAAATTTAAATTTAAAATGTATGCTCGATACTCTGTTTTCCAGGCATGTCTGCAGA 5
276 mAD TAAAGAAATTTAAATTTAAAATGTATGCTCGATACTCTGTTTTCCAGGCATGTCTGCAGA 5
277 sAD TTCCAAAATTCTGAGATTCTTAATTATGTCGAATTTGTCTAAGGTTTTTCTTTTAACACC 5
278 mAD TTCCAAAATTCTGAGATTCTTAATTATGTCGAATTTGTCTAAGGTTTTTCTTTTAACACC 5
279 sAD GAGAGGAAGCCTGTCTTTTCCAGGCTTCTCGAAAGGTAAGGCAGAGTGAGATGGAATCTA 6
280 mAD GAGAGGAAGCCTGTCTTTTCCAGGCTTCTCGAAAGGTAAGGCAGAGTGAGATGGAATCTA 6
281 sAD TTTTAAATCAATAACATTTTAGGGTAAGTCGATTCCTGACTCTTTTTTCTGTGGTTGTGA 3
282 mAD TTTTAAATCAATAACATTTTAGGGTAAGTCGATTCCTGACTCTTTTTTCTGTGGTTGTGA 3
283 sAD AAATACTACCTAGTAAACCCTTATTATCTCGATATATTATCAATATATTTTTTCCCATCA 3
284 mAD AAATACTACCTAGTAAACCCTTATTATCTCGATATATTATCAATATATTTTTTCCCATCA 3
285 sAD GCTTCTTTTCTTTTTTTTTTATATTACTTCGAAGGTGGAACTTAACCCTCCCCTTAAGAA 4
286 mAD GCTTCTTTTCTTTTTTTTTTATATTACTTCGAAGGTGGAACTTAACCCTCCCCTTAAGAA 4
287 mAD GACCACAAAGTGAAGGTAAAAATAAAATTCGAGAATTCAATACATCATGATTCTTTTTTA X
288 sAD GACCACAAAGTGAAGGTAAAAATAAAATTCGAGAATTCAATACATCATGATTCTTTTTTA X
289 sAD CCCGATTACTTCAGATTTACTTACAGCCTCGAGACTTCTTTTTATAACCAAATAATTTTA 2
290 mAD CCCGATTACTTCAGATTTACTTACAGCCTCGAGACTTCTTTTTATAACCAAATAATTTTA 2
291 sAD CTTTTAACAGATCACAATATCAAAAATCTCGAATGTCAACTGTTCTGGTTTTCATGTGAA 15
292 mAD CTTTTAACAGATCACAATATCAAAAATCTCGAATGTCAACTGTTCTGGTTTTCATGTGAA 15
293 sAD GAATAAACATGTGCATAGACAACCATTATCGATTAAAGGAAGATATCTGAGTACAAGCTG 13
294 mAD GAATAAACATGTGCATAGACAACCATTATCGATTAAAGGAAGATATCTGAGTACAAGCTG 13
295 sAD GTCTATCAGTTATCTGTTAAGTTTTGAATCGAGCAGAATACAGCCATATTTTTCTTCTTG 5
296 mAD GTCTATCAGTTATCTGTTAAGTTTTGAATCGAGCAGAATACAGCCATATTTTTCTTCTTG 5
297 sAD AAAATAAGTTGATAGAGGAAAGTATTATTCGAAGCTTGCTGGAATTGTGAGAAAAGTAAG 7
298 mAD AAAATAAGTTGATAGAGGAAAGTATTATTCGAAGCTTGCTGGAATTGTGAGAAAAGTAAG 7
299 sAD TGTTACAACTGAATTTGTTGCATTTTTCTCGAACCACCCTACATGAAAATGGGAAAAACA 1
300 mAD TGTTACAACTGAATTTGTTGCATTTTTCTCGAACCACCCTACATGAAAATGGGAAAAACA 1
301 sAD TGCTCTTTTAGGATAGCTTGAAGTAATTTCGATTTCCCCATTCCTAATCCTTAAATAATG 1
302 mAD TGCTCTTTTAGGATAGCTTGAAGTAATTTCGATTTCCCCATTCCTAATCCTTAAATAATG 1
303 sAD CAGTATTAGGTTACTGATTTCTGATTTTTCGAATGATCTAAAAAAAAAAAAAGTTAGACC 12
304 mAD CAGTATTAGGTTACTGATTTCTGATTTTTCGAATGATCTAAAAAAAAAAAAAGTTAGACC 12
305 sAD GCAATTCATATAGTCTAAAAAATTTTAATCGAGGAAGATTAAGTGACCTGATAAAGTGGA 13
306 mAD GCAATTCATATAGTCTAAAAAATTTTAATCGAGGAAGATTAAGTGACCTGATAAAGTGGA 13
307 mAD TTTTTAAAGAAGGTTTGTATCATATTTCTCGAAGAGTGGCATGCTTTTCCCAAATGTCAC 19
308 sAD TTTTTAAAGAAGGTTTGTATCATATTTCTCGAAGAGTGGCATGCTTTTCCCAAATGTCAC 19
309 sAD AGATTTTTTTTTTTTAAAATGATTTCAATCGAGAGAGTGTTTAAATCCAGAGATTTGTGA 2
310 mAD AGATTTTTTTTTTTTAAAATGATTTCAATCGAGAGAGTGTTTAAATCCAGAGATTTGTGA 2
311 sAD TTGACTCTTTTGAACCTCTTGAGACTTGTCGAAGCAGTCTAATTTTAGGTTTAAAAGAAT 22
312 mAD TTGACTCTTTTGAACCTCTTGAGACTTGTCGAAGCAGTCTAATTTTAGGTTTAAAAGAAT 22
313 sAD ATATATGACCTAACCTATTAAAAAGAGATCGATTGATAATAAAATTTGTCATTTTCTCAG 4
314 mAD ATATATGACCTAACCTATTAAAAAGAGATCGATTGATAATAAAATTTGTCATTTTCTCAG 4
315 sAD ACTTAATTTAACATAATTATTAAATTGATCGACCTACCCATCTTTTAAAATCTTTCTGTC 5
316 mAD ACTTAATTTAACATAATTATTAAATTGATCGACCTACCCATCTTTTAAAATCTTTCTGTC 5
317 sAD TTTTGGTTGAAATGTATACCAACAATTTTCGAACAGAATACATAGAAAGTACCAAGAGAA 6
318 mAD TTTTGGTTGAAATGTATACCAACAATTTTCGAACAGAATACATAGAAAGTACCAAGAGAA 6
319 mAD TTTAAAATGCTTTAAAATTGTTTAAATATCGACTCTAGGATGCCATACCATAAGCATCTT 8
320 sAD TTTAAAATGCTTTAAAATTGTTTAAATATCGACTCTAGGATGCCATACCATAAGCATCTT 8
321 sAD CAGTAATCCTAGAAAGACAACTGATACATCGAATTCCAACTCTCATCACAGTAGCAGCAC 8
322 mAD CAGTAATCCTAGAAAGACAACTGATACATCGAATTCCAACTCTCATCACAGTAGCAGCAC 8
323 sAD TTTCAGAGAAGTATTAACTACAGACATTTCGAAGACGTTATCCCTGTAAATTACCTCTAC 2
324 mAD TTTCAGAGAAGTATTAACTACAGACATTTCGAAGACGTTATCCCTGTAAATTACCTCTAC 2
325 sAD GTTAGAAACTGTTTTTCACAATTAAGTTTCGAATATTACTTTTATTCCCCCCACCAAACT 1
326 mAD GTTAGAAACTGTTTTTCACAATTAAGTTTCGAATATTACTTTTATTCCCCCCACCAAACT 1
327 sAD CTCCTTCAACCTGGTGGATCCACCAGTTTCGACATCTTTAACCAATTACATCTGTAAGAA 12
328 mAD CTCCTTCAACCTGGTGGATCCACCAGTTTCGACATCTTTAACCAATTACATCTGTAAGAA 12
329 mAD CAGCTTGTACTCAGATATCTTCCTTTAATCGATTGGTGAGATTTTTAAGTTCAAAATGTA 13
330 sAD CAGCTTGTACTCAGATATCTTCCTTTAATCGATTGGTGAGATTTTTAAGTTCAAAATGTA 13
表3.c5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
221 62565038 62565069 62592928 62592959 16 62561068 62565069 62588958 62592959
222 62565038 62565069 62592928 62592959 16 62561068 62565069 62588958 62592959
223 47506510 47506541 47549933 47549964 2 47506510 47510511 47549933 47553934
224 47506510 47506541 47549933 47549964 2 47506510 47510511 47549933 47553934
225 19848139 19848170 19898126 19898157 20 19844169 19848170 19898126 19902127
226 19848139 19848170 19898126 19898157 20 19844169 19848170 19898126 19902127
227 107658435 107658466 107699795 107699826 3 107654465 107658466 107695825 107699826
228 107658435 107658466 107699795 107699826 3 107654465 107658466 107695825 107699826
229 39211112 39211143 39287559 39287590 3 39211112 39215113 39283589 39287590
230 39211112 39211143 39287559 39287590 3 39211112 39215113 39283589 39287590
231 154259015 154259046 154312039 154312070 6 154255045 154259046 154308069 154312070
232 154259015 154259046 154312039 154312070 6 154255045 154259046 154308069 154312070
233 40454949 40454980 40488042 40488073 6 40454949 40458950 40488042 40492043
234 40454949 40454980 40488042 40488073 6 40454949 40458950 40488042 40492043
235 221097555 221097586 221141648 221141679 1 221097555 221101556 221137678 221141679
236 221097555 221097586 221141648 221141679 1 221097555 221101556 221137678 221141679
237 106699511 106699542 106728195 106728226 11 106695541 106699542 106724225 106728226
238 106699511 106699542 106728195 106728226 11 106695541 106699542 106724225 106728226
239 60855000 60855031 60904843 60904874 13 60851030 60855031 60904843 60908844
240 60855000 60855031 60904843 60904874 13 60851030 60855031 60904843 60908844
241 38203591 38203622 38243208 38243239 14 38203591 38207592 38239238 38243239
242 38203591 38203622 38243208 38243239 14 38203591 38207592 38239238 38243239
243 15155840 15155871 15194993 15195024 16 15155840 15159841 15191023 15195024
244 15155840 15155871 15194993 15195024 16 15155840 15159841 15191023 15195024
245 117366498 117366529 117423152 117423183 7 117362528 117366529 117423152 117427153
246 117366498 117366529 117423152 117423183 7 117362528 117366529 117423152 117427153
247 116579148 116579179 116593950 116593981 1 116579148 116583149 116593950 116597951
248 116579148 116579179 116593950 116593981 1 116579148 116583149 116593950 116597951
249 138027490 138027521 138075531 138075562 2 138023520 138027521 138071561 138075562
250 138027490 138027521 138075531 138075562 2 138023520 138027521 138071561 138075562
251 46574127 46574158 46643075 46643106 20 46570157 46574158 46643075 46647076
252 46574127 46574158 46643075 46643106 20 46570157 46574158 46643075 46647076
253 127434266 127434297 127460011 127460042 5 127434266 127438267 127460011 127464012
254 127434266 127434297 127460011 127460042 5 127434266 127438267 127460011 127464012
255 102956535 102956566 102980783 102980814 2 102952565 102956566 102980783 102984784
256 102956535 102956566 102980783 102980814 2 102952565 102956566 102980783 102984784
257 92986182 92986213 93038794 93038825 7 92986182 92990183 93038794 93042795
258 92986182 92986213 93038794 93038825 7 92986182 92990183 93038794 93042795
259 84068704 84068735 84135705 84135736 11 84064734 84068735 84131735 84135736
260 84068704 84068735 84135705 84135736 11 84064734 84068735 84131735 84135736
261 35676542 35676573 35751811 35751842 1 35676542 35680543 35747841 35751842
262 35676542 35676573 35751811 35751842 1 35676542 35680543 35747841 35751842
263 59152323 59152354 59205229 59205260 1 59152323 59156324 59201259 59205260
264 59152323 59152354 59205229 59205260 1 59152323 59156324 59201259 59205260
265 82866083 82866114 82889344 82889375 10 82866083 82870084 82889344 82893345
266 82866083 82866114 82889344 82889375 10 82866083 82870084 82889344 82893345
267 42500999 42501030 42536264 42536295 15 42497029 42501030 42536264 42540265
268 42500999 42501030 42536264 42536295 15 42497029 42501030 42536264 42540265
269 209524455 209524486 209561479 209561510 2 209520485 209524486 209557509 209561510
270 209524455 209524486 209561479 209561510 2 209520485 209524486 209557509 209561510
271 46534139 46534170 46569163 46569194 2 46530169 46534170 46569163 46573164
272 46534139 46534170 46569163 46569194 2 46530169 46534170 46569163 46573164
273 37862801 37862832 37889307 37889338 4 37858831 37862832 37889307 37893308
274 37862801 37862832 37889307 37889338 4 37858831 37862832 37889307 37893308
275 124814333 124814364 124884100 124884131 5 124810363 124814364 124880130 124884131
276 124814333 124814364 124884100 124884131 5 124810363 124814364 124880130 124884131
277 74305244 74305275 74329889 74329920 5 74305244 74309245 74325919 74329920
278 74305244 74305275 74329889 74329920 5 74305244 74309245 74325919 74329920
279 137345960 137345991 137362789 137362820 6 137345960 137349961 137362789 137366790
280 137345960 137345991 137362789 137362820 6 137345960 137349961 137362789 137366790
281 67246259 67246290 67291641 67291672 3 67242289 67246290 67291641 67295642
282 67246259 67246290 67291641 67291672 3 67242289 67246290 67291641 67295642
283 192746085 192746116 192807100 192807131 3 192742115 192746116 192807100 192811101
284 192746085 192746116 192807100 192807131 3 192742115 192746116 192807100 192811101
285 59264971 59265002 59348306 59348337 4 59264971 59268972 59344336 59348337
286 59264971 59265002 59348306 59348337 4 59264971 59268972 59344336 59348337
287 39309663 39309694 39333851 39333882 X 39305693 39309694 39329881 39333882
288 39309663 39309694 39333851 39333882 X 39305693 39309694 39329881 39333882
289 209692609 209692640 209738615 209738646 2 209688639 209692640 209734645 209738646
290 209692609 209692640 209738615 209738646 2 209688639 209692640 209734645 209738646
291 58564115 58564146 58585950 58585981 15 58560145 58564146 58581980 58585981
292 58564115 58564146 58585950 58585981 15 58560145 58564146 58581980 58585981
293 97124956 97124987 97199512 97199543 13 97124956 97128957 97195542 97199543
294 97124956 97124987 97199512 97199543 13 97124956 97128957 97195542 97199543
295 159354550 159354581 159380368 159380399 5 159350580 159354581 159376398 159380399
296 159354550 159354581 159380368 159380399 5 159350580 159354581 159376398 159380399
297 93011591 93011622 93038763 93038794 7 93011591 93015592 93034793 93038794
298 93011591 93011622 93038763 93038794 7 93011591 93015592 93034793 93038794
299 69089823 69089854 69164723 69164754 1 69089823 69093824 69164723 69168724
300 69089823 69089854 69164723 69164754 1 69089823 69093824 69164723 69168724
301 76003880 76003911 76086306 76086337 1 75999910 76003911 76082336 76086337
302 76003880 76003911 76086306 76086337 1 75999910 76003911 76082336 76086337
303 75136236 75136267 75166435 75166466 12 75136236 75140237 75166435 75170436
304 75136236 75136267 75166435 75166466 12 75136236 75140237 75166435 75170436
305 33822756 33822787 33873349 33873380 13 33822756 33826757 33873349 33877350
306 33822756 33822787 33873349 33873380 13 33822756 33826757 33873349 33877350
307 46481483 46481514 46545017 46545048 19 46477513 46481514 46541047 46545048
308 46481483 46481514 46545017 46545048 19 46477513 46481514 46541047 46545048
309 5850709 5850740 5932311 5932342 2 5850709 5854710 5928341 5932342
310 5850709 5850740 5932311 5932342 2 5850709 5854710 5928341 5932342
311 25666349 25666380 25695448 25695479 22 25662379 25666380 25691478 25695479
312 25666349 25666380 25695448 25695479 22 25662379 25666380 25691478 25695479
313 125340607 125340638 125357325 125357356 4 125340607 125344608 125357325 125361326
314 125340607 125340638 125357325 125357356 4 125340607 125344608 125357325 125361326
315 74294290 74294321 74391779 74391810 5 74294290 74298291 74387809 74391810
316 74294290 74294321 74391779 74391810 5 74294290 74298291 74387809 74391810
317 486508 486539 555690 555721 6 482538 486539 555690 559691
318 486508 486539 555690 555721 6 482538 486539 555690 559691
319 10103712 10103743 10177377 10177408 8 10099742 10103743 10173407 10177408
320 10103712 10103743 10177377 10177408 8 10099742 10103743 10173407 10177408
321 21022651 21022682 21054445 21054476 8 21022651 21026652 21054445 21058446
322 21022651 21022682 21054445 21054476 8 21022651 21026652 21054445 21058446
323 172804803 172804834 172831811 172831842 2 172800833 172804834 172831811 172835812
324 172804803 172804834 172831811 172831842 2 172800833 172804834 172831811 172835812
325 66141924 66141955 66168785 66168816 1 66141924 66145925 66164815 66168816
326 66141924 66141955 66168785 66168816 1 66141924 66145925 66164815 66168816
327 96219857 96219888 96237099 96237130 12 96219857 96223858 96237099 96241100
328 96219857 96219888 96237099 96237130 12 96219857 96223858 96237099 96241100
329 97124956 97124987 97147277 97147308 13 97124956 97128957 97147277 97151278
330 97124956 97124987 97147277 97147308 13 97124956 97128957 97147277 97151278
表3.c6
   探針 PCR- 引子 1_ID PCR_ 引子 1
221 ORF15_16_62560699_62565069_62586208_62592959_FF OBD159_1801 GTTAGTATGTATTTTCTGTGGATA
222 ORF15_16_62560699_62565069_62586208_62592959_FF OBD159_1801 GTTAGTATGTATTTTCTGTGGATA
223 ORF15_2_47506510_47507935_47549933_47552565_RR OBD159_1805 GAAGCCTGGATTGGAAGCAGATTTGC
224 ORF15_2_47506510_47507935_47549933_47552565_RR OBD159_1805 GAAGCCTGGATTGGAAGCAGATTTGC
225 ORF15_20_19844341_19848170_19898126_19900554_FR OBD159_1809 GGGACATTGAGGTGTTGGTGGCA
226 ORF15_20_19844341_19848170_19898126_19900554_FR OBD159_1809 GGGACATTGAGGTGTTGGTGGCA
227 ORF15_3_107655921_107658466_107697731_107699826_FF OBD159_1813 TCCCTCGGAGCATAGAACTCATCTTC
228 ORF15_3_107655921_107658466_107697731_107699826_FF OBD159_1813 TCCCTCGGAGCATAGAACTCATCTTC
229 ORF15_3_39211112_39215294_39286446_39287590_RF OBD159_1817 AGTGTTTGGTGTCCAGCAAGCAGTGC
230 ORF15_3_39211112_39215294_39286446_39287590_RF OBD159_1817 AGTGTTTGGTGTCCAGCAAGCAGTGC
231 ORF15_6_154255952_154259046_154307704_154312070_FF OBD159_1821 ATGATGCCTTCCTATGTGCCTGGC
232 ORF15_6_154255952_154259046_154307704_154312070_FF OBD159_1821 ATGATGCCTTCCTATGTGCCTGGC
233 ORF15_6_40454949_40456428_40488042_40490875_RR OBD159_1825 GAGGAAGGGAAACAGTCAAGAGGTAT
234 ORF15_6_40454949_40456428_40488042_40490875_RR OBD159_1825 GAGGAAGGGAAACAGTCAAGAGGTAT
235 ORF150_1_221097555_221099745_221139551_221141679_RF OBD159_1829 AGAGGTTTAGAGTTTGGAACATTTGC
236 ORF150_1_221097555_221099745_221139551_221141679_RF OBD159_1829 AGAGGTTTAGAGTTTGGAACATTTGC
237 ORF151_11_106693665_106699542_106725393_106728226_FF OBD159_1833 GCAGAGTTGCCAATCACAGTATTTAT
238 ORF151_11_106693665_106699542_106725393_106728226_FF OBD159_1833 GCAGAGTTGCCAATCACAGTATTTAT
239 ORF152_13_60846170_60855031_60904843_60913572_FR OBD159_1837 CAGAGCAAATGAGTCAACTGAAAA
240 ORF152_13_60846170_60855031_60904843_60913572_FR OBD159_1837 CAGAGCAAATGAGTCAACTGAAAA
241 ORF154_14_38203591_38207960_38231669_38243239_RF OBD159_1841 GAAGGTAAATCTCATAGCAGGCTGGG
242 ORF154_14_38203591_38207960_38231669_38243239_RF OBD159_1841 GAAGGTAAATCTCATAGCAGGCTGGG
243 ORF155_16_15155840_15159398_15192529_15195024_RF OBD159_1845 TGTGAAATAATCAGTCTTGGAAAT
244 ORF155_16_15155840_15159398_15192529_15195024_RF OBD159_1845 TGTGAAATAATCAGTCTTGGAAAT
245 ORF155_7_117353457_117366529_117423152_117425489_FR OBD159_1849 ATTGCTTGAATCTGGAAGGCGGAG
246 ORF155_7_117353457_117366529_117423152_117425489_FR OBD159_1849 ATTGCTTGAATCTGGAAGGCGGAG
247 ORF156_1_116579148_116582139_116593950_116598324_RR OBD159_1853 GAGGGAGGATGTCACTGTTGGTTCCA
248 ORF156_1_116579148_116582139_116593950_116598324_RR OBD159_1853 GAGGGAGGATGTCACTGTTGGTTCCA
249 ORF156_2_138025661_138027521_138071201_138075562_FF OBD159_1857 TGCTGTGCTTGAAGGAAGGATGGTGT
250 ORF156_2_138025661_138027521_138071201_138075562_FF OBD159_1857 TGCTGTGCTTGAAGGAAGGATGGTGT
251 ORF156_20_46570710_46574158_46643075_46649811_FR OBD159_1861 CCTCCTTTTGCCTCCGATTCCTC
252 ORF156_20_46570710_46574158_46643075_46649811_FR OBD159_1861 CCTCCTTTTGCCTCCGATTCCTC
253 ORF156_5_127434266_127436041_127460011_127467027_RR OBD159_1865 CTTGGCATAAAGCAGGGCTCCAGGAA
254 ORF156_5_127434266_127436041_127460011_127467027_RR OBD159_1865 CTTGGCATAAAGCAGGGCTCCAGGAA
255 ORF158_2_102946170_102956566_102980783_102983000_FR OBD159_1869 CTATTTGCTTCCATCTCTTCTTCAAG
256 ORF158_2_102946170_102956566_102980783_102983000_FR OBD159_1869 CTATTTGCTTCCATCTCTTCTTCAAG
257 ORF158_7_92986182_92992000_93038794_93043170_RR OBD159_1873 CTAACACAATGGTAGACACATAGCAA
258 ORF158_7_92986182_92992000_93038794_93043170_RR OBD159_1873 CTAACACAATGGTAGACACATAGCAA
259 ORF159_11_84067130_84068735_84133096_84135736_FF OBD159_1877 ATGGAGTTCCCAGACTTAGCAAATAA
260 ORF159_11_84067130_84068735_84133096_84135736_FF OBD159_1877 ATGGAGTTCCCAGACTTAGCAAATAA
261 ORF16_1_35676542_35678104_35750293_35751842_RF OBD159_1881 GAGAAAAGGTGGGTAGGGAGTAGAGC
262 ORF16_1_35676542_35678104_35750293_35751842_RF OBD159_1881 GAGAAAAGGTGGGTAGGGAGTAGAGC
263 ORF16_1_59152323_59153557_59201894_59205260_RF OBD159_1885 TAACTTACAGGTCCCACAGATTAGGA
264 ORF16_1_59152323_59153557_59201894_59205260_RF OBD159_1885 TAACTTACAGGTCCCACAGATTAGGA
265 ORF16_10_82866083_82869829_82889344_82893485_RR OBD159_1889 CTAAATCCTGAGTGTCTTTCCATCCA
266 ORF16_10_82866083_82869829_82889344_82893485_RR OBD159_1889 CTAAATCCTGAGTGTCTTTCCATCCA
267 ORF16_15_42499291_42501030_42536264_42540825_FR OBD159_1893 GGAAGTGGATTATGGAGCCAGGAAAC
268 ORF16_15_42499291_42501030_42536264_42540825_FR OBD159_1893 GGAAGTGGATTATGGAGCCAGGAAAC
269 ORF16_2_209522065_209524486_209555031_209561510_FF OBD159_1897 CACACATAATCCAGAGTCAGGGAGAG
270 ORF16_2_209522065_209524486_209555031_209561510_FF OBD159_1897 CACACATAATCCAGAGTCAGGGAGAG
271 ORF16_2_46531602_46534170_46569163_46570628_FR OBD159_1901 TTTCTCCTACTTTGGATTTGTTGAGC
272 ORF16_2_46531602_46534170_46569163_46570628_FR OBD159_1901 TTTCTCCTACTTTGGATTTGTTGAGC
273 ORF16_4_37859966_37862832_37889307_37892348_FR OBD159_1905 CTTACAGCCTTCCAAAATAACTCCAG
274 ORF16_4_37859966_37862832_37889307_37892348_FR OBD159_1905 CTTACAGCCTTCCAAAATAACTCCAG
275 ORF16_5_124808480_124814364_124880024_124884131_FF OBD159_1909 TAGTTAGTTACCCATCTGTTTCTA
276 ORF16_5_124808480_124814364_124880024_124884131_FF OBD159_1909 TAGTTAGTTACCCATCTGTTTCTA
277 ORF16_5_74305244_74313564_74325511_74329920_RF OBD159_1913 CCACTCAGCCTCACAGAGCCTCA
278 ORF16_5_74305244_74313564_74325511_74329920_RF OBD159_1913 CCACTCAGCCTCACAGAGCCTCA
279 ORF16_6_137345960_137347521_137362789_137365756_RR OBD159_1917 CCTTTATCTCAAACTCCTCCAGTAGG
280 ORF16_6_137345960_137347521_137362789_137365756_RR OBD159_1917 CCTTTATCTCAAACTCCTCCAGTAGG
281 ORF160_3_67234045_67246290_67291641_67297587_FR OBD159_1921 CTGAACCTGTTTGTAAGTTGAGGGTG
282 ORF160_3_67234045_67246290_67291641_67297587_FR OBD159_1921 CTGAACCTGTTTGTAAGTTGAGGGTG
283 ORF161_3_192744752_192746116_192807100_192810430_FR OBD159_1925 CTATGCTCAAGAGAACTAAAGTAGGA
284 ORF161_3_192744752_192746116_192807100_192810430_FR OBD159_1925 CTATGCTCAAGAGAACTAAAGTAGGA
285 ORF161_4_59264971_59267015_59339329_59348337_RF OBD159_1929 CAAGATACCAGTGTTAGGTTGTGAAA
286 ORF161_4_59264971_59267015_59339329_59348337_RF OBD159_1929 CAAGATACCAGTGTTAGGTTGTGAAA
287 ORF162_X_39303922_39309694_39331263_39333882_FF OBD159_1933 GTCTGGGAGGCATTTGGAGCATC
288 ORF162_X_39303922_39309694_39331263_39333882_FF OBD159_1933 GTCTGGGAGGCATTTGGAGCATC
289 ORF163_2_209684451_209692640_209735707_209738646_FF OBD159_1937 GCTTATTTCCTGAACGCACTTGCCTA
290 ORF163_2_209684451_209692640_209735707_209738646_FF OBD159_1937 GCTTATTTCCTGAACGCACTTGCCTA
291 ORF164_15_58557606_58564146_58584664_58585981_FF OBD159_1941 GCCAGTCCAAGGTGCTGTGGTAG
292 ORF164_15_58557606_58564146_58584664_58585981_FF OBD159_1941 GCCAGTCCAAGGTGCTGTGGTAG
293 ORF165_13_97124956_97128666_97195242_97199543_RF OBD159_1945 ATCTATGCCTGCCACAAAGTAGGG
294 ORF165_13_97124956_97128666_97195242_97199543_RF OBD159_1945 ATCTATGCCTGCCACAAAGTAGGG
295 ORF165_5_159344811_159354581_159378555_159380399_FF OBD159_1949 TGATGAGGTTGTAATGTTATTTCA
296 ORF165_5_159344811_159354581_159378555_159380399_FF OBD159_1949 TGATGAGGTTGTAATGTTATTTCA
297 ORF169_7_93011591_93016612_93036188_93038794_RF OBD159_1953 GAAGAATAATGAAACCTCCTGGAAGG
298 ORF169_7_93011591_93016612_93036188_93038794_RF OBD159_1953 GAAGAATAATGAAACCTCCTGGAAGG
299 ORF17_1_69089823_69102269_69164723_69166979_RR OBD159_1957 TAGTGCCTGAGGAGACATCTTACAGC
300 ORF17_1_69089823_69102269_69164723_69166979_RR OBD159_1957 TAGTGCCTGAGGAGACATCTTACAGC
301 ORF17_1_76000194_76003911_76083373_76086337_FF OBD159_1961 GGCAGAAGCAGAACTTGGCTCTTATT
302 ORF17_1_76000194_76003911_76083373_76086337_FF OBD159_1961 GGCAGAAGCAGAACTTGGCTCTTATT
303 ORF17_12_75136236_75139196_75166435_75186315_RR OBD159_1965 GGTGAGCGTAGTTGTTCATAATAGTC
304 ORF17_12_75136236_75139196_75166435_75186315_RR OBD159_1965 GGTGAGCGTAGTTGTTCATAATAGTC
305 ORF17_13_33822756_33828516_33873349_33876786_RR OBD159_1969 TCCAGGTATCTACTTTTCTTCTAT
306 ORF17_13_33822756_33828516_33873349_33876786_RR OBD159_1969 TCCAGGTATCTACTTTTCTTCTAT
307 ORF17_19_46479838_46481514_46541191_46545048_FF OBD159_1973 GGTCTGAACACAGTCTTGGCTGG
308 ORF17_19_46479838_46481514_46541191_46545048_FF OBD159_1973 GGTCTGAACACAGTCTTGGCTGG
309 ORF17_2_5850709_5859559_5924503_5932342_RF OBD159_1977 CCCAGGTCTCCAGGTCTCCTTAG
310 ORF17_2_5850709_5859559_5924503_5932342_RF OBD159_1977 CCCAGGTCTCCAGGTCTCCTTAG
311 ORF17_22_25661627_25666380_25694410_25695479_FF OBD159_1981 GCCTGTTGCGGTTCTTTCTGTTGAA
312 ORF17_22_25661627_25666380_25694410_25695479_FF OBD159_1981 GCCTGTTGCGGTTCTTTCTGTTGAA
313 ORF17_4_125340607_125343598_125357325_125363715_RR OBD159_1985 GAAACTGGAAAACTTTAGAGAAGAGC
314 ORF17_4_125340607_125343598_125357325_125363715_RR OBD159_1985 GAAACTGGAAAACTTTAGAGAAGAGC
315 ORF17_5_74294290_74298111_74386498_74391810_RF OBD159_1989 CTTGGCGATTTGTATGAGTAGGTTGC
316 ORF17_5_74294290_74298111_74386498_74391810_RF OBD159_1989 CTTGGCGATTTGTATGAGTAGGTTGC
317 ORF17_6_482421_486539_555690_558488_FR OBD159_1993 GGCAAAACAAATACTTCCTGGGCATT
318 ORF17_6_482421_486539_555690_558488_FR OBD159_1993 GGCAAAACAAATACTTCCTGGGCATT
319 ORF17_8_10100695_10103743_10175271_10177408_FF OBD159_1997 AGTGAGATAATGTGCCTGAAAGCAAT
320 ORF17_8_10100695_10103743_10175271_10177408_FF OBD159_1997 AGTGAGATAATGTGCCTGAAAGCAAT
321 ORF17_8_21022651_21025530_21054445_21056962_RR OBD159_2001 CGGGAGGTTTCTGTGAGAGGTGTTCT
322 ORF17_8_21022651_21025530_21054445_21056962_RR OBD159_2001 CGGGAGGTTTCTGTGAGAGGTGTTCT
323 ORF173_2_172799773_172804834_172831811_172834823_FR OBD159_2005 TCCCAAGGGCACCTGCTCACAAG
324 ORF173_2_172799773_172804834_172831811_172834823_FR OBD159_2005 TCCCAAGGGCACCTGCTCACAAG
325 ORF174_1_66141924_66143825_66164982_66168816_RF OBD159_2009 GGGAGAATGAGGAATGAGGACCG
326 ORF174_1_66141924_66143825_66164982_66168816_RF OBD159_2009 GGGAGAATGAGGAATGAGGACCG
327 ORF174_12_96219857_96223649_96237099_96241349_RR OBD159_2013 ATCATCAGAGGATTACTCAGAGGG
328 ORF174_12_96219857_96223649_96237099_96241349_RR OBD159_2013 ATCATCAGAGGATTACTCAGAGGG
329 ORF174_13_97124956_97128666_97147277_97152656_RR OBD159_2017 CTCTTTCTGAGGCTTTTGTTCATA
330 ORF174_13_97124956_97128666_97147277_97152656_RR OBD159_2017 CTCTTTCTGAGGCTTTTGTTCATA
表3.c7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
221 OBD159_1803 GTATTTTGTTATCTTACCTAATGGA OBD159_1801_1803 0.001962204
222 OBD159_1803 GTATTTTGTTATCTTACCTAATGGA OBD159_1801_1803 0.001962204
223 OBD159_1807 CTATTGCTATGTCTTCAAGTTCAACC OBD159_1805_1807 0.001626338
224 OBD159_1807 CTATTGCTATGTCTTCAAGTTCAACC OBD159_1805_1807 0.001626338
225 OBD159_1811 GAAGTCCCCTGGCGAAGATGAGC OBD159_1809_1811 0.000814341
226 OBD159_1811 GAAGTCCCCTGGCGAAGATGAGC OBD159_1809_1811 0.000814341
227 OBD159_1815 GGCTCTGACATAACTCCACAAGGGTA OBD159_1813_1815 0.001480022
228 OBD159_1815 GGCTCTGACATAACTCCACAAGGGTA OBD159_1813_1815 0.001480022
229 OBD159_1819 GGTCGGATTCTGGCTACATTTTGAAG OBD159_1817_1819 0.00207786
230 OBD159_1819 GGTCGGATTCTGGCTACATTTTGAAG OBD159_1817_1819 0.00207786
231 OBD159_1823 GTGTGTAGTCAGTCAATGGGAAGGAA OBD159_1821_1823 0.002644379
232 OBD159_1823 GTGTGTAGTCAGTCAATGGGAAGGAA OBD159_1821_1823 0.002644379
233 OBD159_1827 GACCTGTTTCCCTCCCAAGAGCCTAT OBD159_1825_1827 0.001541761
234 OBD159_1827 GACCTGTTTCCCTCCCAAGAGCCTAT OBD159_1825_1827 0.001541761
235 OBD159_1831 CACTTTGTTGCCTGAGTTGCCTA OBD159_1829_1831 0.000897371
236 OBD159_1831 CACTTTGTTGCCTGAGTTGCCTA OBD159_1829_1831 0.000897371
237 OBD159_1835 CCAATGGCTCCCAACTTCCCACTAAT OBD159_1833_1835 0.00142553
238 OBD159_1835 CCAATGGCTCCCAACTTCCCACTAAT OBD159_1833_1835 0.00142553
239 OBD159_1839 CAAGTAACTCTTATTATTTTGAGGT OBD159_1837_1839 0.000674976
240 OBD159_1839 CAAGTAACTCTTATTATTTTGAGGT OBD159_1837_1839 0.000674976
241 OBD159_1843 CATAAAAGCAGAACAGGAGCACATTC OBD159_1841_1843 0.000851875
242 OBD159_1843 CATAAAAGCAGAACAGGAGCACATTC OBD159_1841_1843 0.000851875
243 OBD159_1847 CCAAAGTGCTGGGATTACAGGCAT OBD159_1845_1847 0.001606372
244 OBD159_1847 CCAAAGTGCTGGGATTACAGGCAT OBD159_1845_1847 0.001606372
245 OBD159_1851 TTTTCTCCCAGTGATTATTATGTA OBD159_1849_1851 0.000653215
246 OBD159_1851 TTTTCTCCCAGTGATTATTATGTA OBD159_1849_1851 0.000653215
247 OBD159_1855 AATCCTCTCTTGACTGACCTGGCATA OBD159_1853_1855 0.000349443
248 OBD159_1855 AATCCTCTCTTGACTGACCTGGCATA OBD159_1853_1855 0.000349443
249 OBD159_1859 TAGGCTGTTTCAGTGACCCAGAA OBD159_1857_1859 0.000559234
250 OBD159_1859 TAGGCTGTTTCAGTGACCCAGAA OBD159_1857_1859 0.000559234
251 OBD159_1863 TATCTTTGGTGCCAGCCCCGTGC OBD159_1861_1863 0.000600787
252 OBD159_1863 TATCTTTGGTGCCAGCCCCGTGC OBD159_1861_1863 0.000600787
253 OBD159_1867 AACTCCTTTACTGCTTTGACCACCAT OBD159_1865_1867 0.001137489
254 OBD159_1867 AACTCCTTTACTGCTTTGACCACCAT OBD159_1865_1867 0.001137489
255 OBD159_1871 TGGCTATGAAGGGCAGGAGAGGAATA OBD159_1869_1871 0.001002895
256 OBD159_1871 TGGCTATGAAGGGCAGGAGAGGAATA OBD159_1869_1871 0.001002895
257 OBD159_1875 CCTGTTGAATGACTAACTGGATGAGA OBD159_1873_1875 0.001335563
258 OBD159_1875 CCTGTTGAATGACTAACTGGATGAGA OBD159_1873_1875 0.001335563
259 OBD159_1879 GTAGTCAGGCAAAGAGAGTAGGGCAT OBD159_1877_1879 0.000872807
260 OBD159_1879 GTAGTCAGGCAAAGAGAGTAGGGCAT OBD159_1877_1879 0.000872807
261 OBD159_1883 CCCTGTATTCTTAGGCACCAAGTCTT OBD159_1881_1883 0.002374347
262 OBD159_1883 CCCTGTATTCTTAGGCACCAAGTCTT OBD159_1881_1883 0.002374347
263 OBD159_1887 CTTACTTTGCTCAATCAGTTCCTCTG OBD159_1885_1887 0.001221285
264 OBD159_1887 CTTACTTTGCTCAATCAGTTCCTCTG OBD159_1885_1887 0.001221285
265 OBD159_1891 CCCTCTCCAAACCTCCTTCTCTCAAG OBD159_1889_1891 0.00118351
266 OBD159_1891 CCCTCTCCAAACCTCCTTCTCTCAAG OBD159_1889_1891 0.00118351
267 OBD159_1895 GCTTTACCTGTGTTACCACTCTATGC OBD159_1893_1895 0.00149186
268 OBD159_1895 GCTTTACCTGTGTTACCACTCTATGC OBD159_1893_1895 0.00149186
269 OBD159_1899 TGGGTTTGGTAGGGCTTTATTCCAGC OBD159_1897_1899 0.003011204
270 OBD159_1899 TGGGTTTGGTAGGGCTTTATTCCAGC OBD159_1897_1899 0.003011204
271 OBD159_1903 GGAGGAGGTTCACACTACGGGATAAA OBD159_1901_1903 0.001177423
272 OBD159_1903 GGAGGAGGTTCACACTACGGGATAAA OBD159_1901_1903 0.001177423
273 OBD159_1907 ATGGCATTCCCTGATTTCCCTGGATG OBD159_1905_1907 0.000802563
274 OBD159_1907 ATGGCATTCCCTGATTTCCCTGGATG OBD159_1905_1907 0.000802563
275 OBD159_1911 GAACACCCTAAACGAGCAGGAGAT OBD159_1909_1911 0.000582061
276 OBD159_1911 GAACACCCTAAACGAGCAGGAGAT OBD159_1909_1911 0.000582061
277 OBD159_1915 CCACTTCCATCCCCTTCACCACT OBD159_1913_1915 0.00126299
278 OBD159_1915 CCACTTCCATCCCCTTCACCACT OBD159_1913_1915 0.00126299
279 OBD159_1919 GAGAAAGGAGAGGGAAAACAGTGGGC OBD159_1917_1919 0.000643972
280 OBD159_1919 GAGAAAGGAGAGGGAAAACAGTGGGC OBD159_1917_1919 0.000643972
281 OBD159_1923 CTCTGCTGTGGGTGGTGTTGAATGTC OBD159_1921_1923 0.001555442
282 OBD159_1923 CTCTGCTGTGGGTGGTGTTGAATGTC OBD159_1921_1923 0.001555442
283 OBD159_1927 GGGTCTTGCCAGTAAGTTCTGAATGG OBD159_1925_1927 0.000396146
284 OBD159_1927 GGGTCTTGCCAGTAAGTTCTGAATGG OBD159_1925_1927 0.000396146
285 OBD159_1931 GAGAGTCACTAAGTCCAATCTATTCT OBD159_1929_1931 0.000368359
286 OBD159_1931 GAGAGTCACTAAGTCCAATCTATTCT OBD159_1929_1931 0.000368359
287 OBD159_1935 GGGACTCCAGATTGGTTGGCTGC OBD159_1933_1935 0.000316159
288 OBD159_1935 GGGACTCCAGATTGGTTGGCTGC OBD159_1933_1935 0.000316159
289 OBD159_1939 GCTGAAGACTTGGTCAAACCTATGGC OBD159_1937_1939 0.002317868
290 OBD159_1939 GCTGAAGACTTGGTCAAACCTATGGC OBD159_1937_1939 0.002317868
291 OBD159_1943 CACAGACCAAGGACCCTAACCAC OBD159_1941_1943 0.001584871
292 OBD159_1943 CACAGACCAAGGACCCTAACCAC OBD159_1941_1943 0.001584871
293 OBD159_1947 CTCTTTCTGAGGCTTTTGTTCATA OBD159_1945_1947 0.001610864
294 OBD159_1947 CTCTTTCTGAGGCTTTTGTTCATA OBD159_1945_1947 0.001610864
295 OBD159_1951 TTCCTTCCCCAGGGTTATTCCTTG OBD159_1949_1951 0.000903487
296 OBD159_1951 TTCCTTCCCCAGGGTTATTCCTTG OBD159_1949_1951 0.000903487
297 OBD159_1955 GCTCATAGAAGAAGCCTTTGGGC OBD159_1953_1955 0.001642727
298 OBD159_1955 GCTCATAGAAGAAGCCTTTGGGC OBD159_1953_1955 0.001642727
299 OBD159_1959 GCTACCTTTCCAGTTAGGGATTCAGC OBD159_1957_1959 0.001162769
300 OBD159_1959 GCTACCTTTCCAGTTAGGGATTCAGC OBD159_1957_1959 0.001162769
301 OBD159_1963 CCACTTCTTTGCTGGCTAACAGGGAG OBD159_1961_1963 0.001956069
302 OBD159_1963 CCACTTCTTTGCTGGCTAACAGGGAG OBD159_1961_1963 0.001956069
303 OBD159_1967 TGTGTATTCTGCTGATGTTGGTGGAA OBD159_1965_1967 0.001893861
304 OBD159_1967 TGTGTATTCTGCTGATGTTGGTGGAA OBD159_1965_1967 0.001893861
305 OBD159_1971 CAGCAGAGTATTTGGAGTTGAAAA OBD159_1969_1971 0.000425074
306 OBD159_1971 CAGCAGAGTATTTGGAGTTGAAAA OBD159_1969_1971 0.000425074
307 OBD159_1975 CTCACGCCTGGGAGAGTTTGTGC OBD159_1973_1975 0.001135474
308 OBD159_1975 CTCACGCCTGGGAGAGTTTGTGC OBD159_1973_1975 0.001135474
309 OBD159_1979 GCTGAGTTGAGCCTTCTGCTTGG OBD159_1977_1979 0.001365566
310 OBD159_1979 GCTGAGTTGAGCCTTCTGCTTGG OBD159_1977_1979 0.001365566
311 OBD159_1983 ATGTGCTAATCTGGAAGACTCTGTC OBD159_1981_1983 0.001999821
312 OBD159_1983 ATGTGCTAATCTGGAAGACTCTGTC OBD159_1981_1983 0.001999821
313 OBD159_1987 GCAGTAAAATCCATAAGAATGAGCAG OBD159_1985_1987 0.000704424
314 OBD159_1987 GCAGTAAAATCCATAAGAATGAGCAG OBD159_1985_1987 0.000704424
315 OBD159_1991 TGGGAAGTGAGAAGAGGAGGTGGCAA OBD159_1989_1991 0.001666152
316 OBD159_1991 TGGGAAGTGAGAAGAGGAGGTGGCAA OBD159_1989_1991 0.001666152
317 OBD159_1995 CTAAGTGTCAGTCAACCCCTCTCCTA OBD159_1993_1995 0.001044019
318 OBD159_1995 CTAAGTGTCAGTCAACCCCTCTCCTA OBD159_1993_1995 0.001044019
319 OBD159_1999 AGACAGGTGGTGCTGATTCATTGGTG OBD159_1997_1999 0.002021208
320 OBD159_1999 AGACAGGTGGTGCTGATTCATTGGTG OBD159_1997_1999 0.002021208
321 OBD159_2003 GTTTATTCACCTTCTCCCTGGTCTCA OBD159_2001_2003 0.001330657
322 OBD159_2003 GTTTATTCACCTTCTCCCTGGTCTCA OBD159_2001_2003 0.001330657
323 OBD159_2007 GGGATGCTTGCCTTGATGAGTGC OBD159_2005_2007 0.002083668
324 OBD159_2007 GGGATGCTTGCCTTGATGAGTGC OBD159_2005_2007 0.002083668
325 OBD159_2011 CCTGCGAGGCTTCTGAGCAACAG OBD159_2009_2011 0.000189924
326 OBD159_2011 CCTGCGAGGCTTCTGAGCAACAG OBD159_2009_2011 0.000189924
327 OBD159_2015 AAAGGGCTCCTCTGACCCATAAACCT OBD159_2013_2015 0.00176577
328 OBD159_2015 AAAGGGCTCCTCTGACCCATAAACCT OBD159_2013_2015 0.00176577
329 OBD159_2019 CAGAGGTAAGGACAACTGCCAATA OBD159_2017_2019 0.002913338
330 OBD159_2019 CAGAGGTAAGGACAACTGCCAATA OBD159_2017_2019 0.002913338
表3.c8
   基因
221 rs150252171; rs288604
222 rs150252171; rs288604
223 KCNK12; MSH2; rs267608023
224 KCNK12; MSH2; rs267608023
225 RIN2; rs4813376; rs6046396; rs16981145
226 RIN2; rs4813376; rs6046396; rs16981145
227 BBX; rs11710737
228 BBX; rs11710737
229 CX3CR1; XIRP1; rs1877563; rs3732378; rs3732379; rs9868689; rs12636547; rs2669845; rs11715522; rs2853707
230 CX3CR1; XIRP1; rs1877563; rs3732378; rs3732379; rs9868689; rs12636547; rs2669845; rs11715522; rs2853707
231 CNKSR3; IPCEF1; OPRM1
232 CNKSR3; IPCEF1; OPRM1
233 LRFN2; rs148347825
234 LRFN2; rs148347825
235 rs12127195
236 rs12127195
237 GUCY1A2
238 GUCY1A2
239 TDRD3; rs7337573
240 TDRD3; rs7337573
241 CLEC14A; SSTR1; rs11622412
242 CLEC14A; SSTR1; rs11622412
243 PDXDC1; rs4003228
244 PDXDC1; rs4003228
245 ASZ1; WNT2; rs2188554; rs10249651
246 ASZ1; WNT2; rs2188554; rs10249651
247 CD58; IGSF3; rs724160030
248 CD58; IGSF3; rs724160030
249 HNMT
250 HNMT
251 SLC13A3; rs847058; rs6066043
252 SLC13A3; rs847058; rs6066043
253 MEGF10; rs387907071; rs387907072; rs199750143; rs794726678; rs989552169; rs794726677
254 MEGF10; rs387907071; rs387907072; rs199750143; rs794726678; rs989552169; rs794726677
255 TMEM182; rs12105421
256 TMEM182; rs12105421
257 rs12671937; rs739385
258 rs12671937; rs739385
259 DLG2; rs790356
260 DLG2; rs790356
261 C1orf216; CLSPN; PSMB2
262 C1orf216; CLSPN; PSMB2
263 rs12144699; rs6700125
264 rs12144699; rs6700125
265 NRG3; rs17101017; rs17685233
266 NRG3; rs17101017; rs17685233
267 HAUS2; LRRC57; SNAP23
268 HAUS2; LRRC57; SNAP23
269 MAP2; rs9288410
270 MAP2; rs9288410
271 ATP6V1E2; PIGF; RHOQ
272 ATP6V1E2; PIGF; RHOQ
273 GAFA3; PGM2; TBC1D1; rs17578878
274 GAFA3; PGM2; TBC1D1; rs17578878
275 ZNF608; rs4357030
276 ZNF608; rs4357030
277 rs167025; rs80337801
278 rs167025; rs80337801
279 OLIG3; rs13201877
280 OLIG3; rs13201877
281 KBTBD8; SUCLG2
282 KBTBD8; SUCLG2
283 FGF12; MB21D2
284 FGF12; MB21D2
285 NA
286 NA
287 rs5917854
288 rs5917854
289 MAP2; UNC80; rs146432517
290 MAP2; UNC80; rs146432517
291 LIPC; rs113298164; rs1365771; rs60439253; rs6494025; rs7178362
292 LIPC; rs113298164; rs1365771; rs60439253; rs6494025; rs7178362
293 MBNL2; OXGR1
294 MBNL2; OXGR1
295 rs953861; rs6556411; rs6556412; rs4379175; rs10045431
296 rs953861; rs6556411; rs6556412; rs4379175; rs10045431
297 rs12671937; rs739385
298 rs12671937; rs739385
299 rs9436866; rs10789285
300 rs9436866; rs10789285
301 ST6GALNAC3; rs12095069
302 ST6GALNAC3; rs12095069
303 CAPS2; KCNC2
304 CAPS2; KCNC2
305 RFC3; rs12429186
306 RFC3; rs12429186
307 PNMAL1; PNMAL2; PPP5D1
308 PNMAL1; PNMAL2; PPP5D1
309 rs16864170; rs10929925
310 rs16864170; rs10929925
311 ADRBK2; rs8142284; rs12158587
312 ADRBK2; rs8142284; rs12158587
313 FAT4; rs1039808
314 FAT4; rs1039808
315 rs80337801; rs12517545; rs167025
316 rs80337801; rs12517545; rs167025
317 EXOC2; rs116446171; rs950039; rs9392056; rs6918152; rs2476847; rs12210050
318 EXOC2; rs116446171; rs950039; rs9392056; rs6918152; rs2476847; rs12210050
319 MSRA; rs10087178; rs10107815; rs73191547; rs7012397
320 MSRA; rs10087178; rs10107815; rs73191547; rs7012397
321 rs500816; rs7015657
322 rs500816; rs7015657
323 RAPGEF4; rs733331
324 RAPGEF4; rs733331
325 PDE4B; rs490094
326 PDE4B; rs490094
327 ELK3; rs4762284
328 ELK3; rs4762284
329 MBNL2; OXGR1
330 MBNL2; OXGR1
表3.c9
   探針 基因座
331 ORF175_1_50024584_50030848_50095924_50103322_RF AGBL4; ELAVL4; rs11583200
332 ORF175_1_50024584_50030848_50095924_50103322_RF AGBL4; ELAVL4; rs11583200
333 ORF176_14_39721868_39724679_39792290_39806170_RR rs17109786; rs148431766
334 ORF176_14_39721868_39724679_39792290_39806170_RR rs17109786; rs148431766
335 ORF176_19_46479838_46481514_46541191_46545048_FF PNMAL1; PNMAL2; PPP5D1
336 ORF176_19_46479838_46481514_46541191_46545048_FF PNMAL1; PNMAL2; PPP5D1
337 ORF176_20_1283617_1286683_1342450_1344929_RF FKBP1A; RAD21L1; RP11-314N13.10; SDCBP2; SNPH; rs35367003
338 ORF176_20_1283617_1286683_1342450_1344929_RF FKBP1A; RAD21L1; RP11-314N13.10; SDCBP2; SNPH; rs35367003
339 ORF177_13_36604370_36613394_36670823_36673255_FR SERTM1; rs11619726
340 ORF177_13_36604370_36613394_36670823_36673255_FR SERTM1; rs11619726
341 ORF177_6_148168867_148173481_148222776_148224891_RF rs6914622; rs9497965; rs9497975
342 ORF177_6_148168867_148173481_148222776_148224891_RF rs6914622; rs9497965; rs9497975
343 ORF177_X_40505666_40507827_40520869_40522158_RR BCOR; rs2968915
344 ORF177_X_40505666_40507827_40520869_40522158_RR BCOR; rs2968915
345 ORF179_5_7540900_7542383_7555641_7557907_FR ADCY2; rs17231202; rs10512928; rs884964; rs12522444; rs11134242
346 ORF179_5_7540900_7542383_7555641_7557907_FR ADCY2; rs17231202; rs10512928; rs884964; rs12522444; rs11134242
347 ORF18_10_121564423_121570750_121595209_121596934_FR FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs755001161
348 ORF18_10_121564423_121570750_121595209_121596934_FR FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs755001161
349 ORF18_18_23859209_23862260_23887990_23889494_RR LAMA3; rs1057516512; rs80356678; rs1057516743; rs1057517023; rs1057516475; rs1057517235; rs1057517367; rs7237244
350 ORF18_18_23859209_23862260_23887990_23889494_RR LAMA3; rs1057516512; rs80356678; rs1057516743; rs1057517023; rs1057516475; rs1057517235; rs1057517367; rs7237244
351 ORF18_2_79981700_79985274_80035781_80037454_RF CTNNA2; rs6738962
352 ORF18_2_79981700_79985274_80035781_80037454_RF CTNNA2; rs6738962
353 ORF18_20_19885722_19887043_19898126_19900554_RR RIN2; rs6046396
354 ORF18_20_19885722_19887043_19898126_19900554_RR RIN2; rs6046396
355 ORF18_21_14553845_14555723_14583254_14600479_FF AF165138.7; HSPA13; SAMSN1
356 ORF18_21_14553845_14555723_14583254_14600479_FF AF165138.7; HSPA13; SAMSN1
357 ORF18_3_46488317_46491053_46529967_46536322_FF LRRC2; LTF; RTP3
358 ORF18_3_46488317_46491053_46529967_46536322_FF LRRC2; LTF; RTP3
359 ORF18_3_64194265_64195323_64266976_64268244_FR PRICKLE2; rs17404667
360 ORF18_3_64194265_64195323_64266976_64268244_FR PRICKLE2; rs17404667
361 ORF18_6_169230654_169232256_169286051_169290790_RR THBS2; rs9406328; rs761646500; rs116146467
362 ORF18_6_169230654_169232256_169286051_169290790_RR THBS2; rs9406328; rs761646500; rs116146467
363 ORF180_3_69108055_69110182_69214794_69217124_RF ARL6IP5; FRMD4B; LMOD3; rs724159964; rs727502798; rs727502799; rs724159965; rs727502797; rs6787362; rs6806528
364 ORF180_3_69108055_69110182_69214794_69217124_RF ARL6IP5; FRMD4B; LMOD3; rs724159964; rs727502798; rs727502799; rs724159965; rs727502797; rs6787362; rs6806528
365 ORF180_4_88335985_88339586_88412084_88413091_RR HERC6; rs12512051
366 ORF180_4_88335985_88339586_88412084_88413091_RR HERC6; rs12512051
367 ORF181_11_84860156_84861867_84918402_84924862_RR DLG2
368 ORF181_11_84860156_84861867_84918402_84924862_RR DLG2
369 ORF182_1_206383244_206385305_206447306_206449267_FF SRGAP2; rs2987927; rs2480408
370 ORF182_1_206383244_206385305_206447306_206449267_FF SRGAP2; rs2987927; rs2480408
371 ORF183_15_74122056_74124006_74177775_74179553_FF ISLR; ISLR2; STRA6; rs376998994; rs397514639
372 ORF183_15_74122056_74124006_74177775_74179553_FF ISLR; ISLR2; STRA6; rs376998994; rs397514639
373 ORF183_2_56270885_56277617_56323476_56329636_FF CCDC85A; rs6747380
374 ORF183_2_56270885_56277617_56323476_56329636_FF CCDC85A; rs6747380
375 ORF183_21_45837532_45839027_45849840_45851551_FF PCBP3; rs56127133
376 ORF183_21_45837532_45839027_45849840_45851551_FF PCBP3; rs56127133
377 ORF184_Y_14466176_14474218_14520608_14523189_FR NLGN4Y
378 ORF184_Y_14466176_14474218_14520608_14523189_FR NLGN4Y
379 ORF187_2_21325579_21332004_21374795_21382106_FR rs2337901; rs11897825
380 ORF187_2_21325579_21332004_21374795_21382106_FR rs2337901; rs11897825
381 ORF187_6_70128487_70130693_70187099_70190406_RF COL19A1; rs771562232; rs658805
382 ORF187_6_70128487_70130693_70187099_70190406_RF COL19A1; rs771562232; rs658805
383 ORF187_7_37211489_37214787_37231292_37233848_RF ELMO1; rs73112661
384 ORF187_7_37211489_37214787_37231292_37233848_RF ELMO1; rs73112661
385 ORF187_8_74044912_74046076_74077219_74079715_RF LY96; rs6472827
386 ORF187_8_74044912_74046076_74077219_74079715_RF LY96; rs6472827
387 ORF188_11_104895593_104903291_104915537_104922612_RR CASP4; rs497116
388 ORF188_11_104895593_104903291_104915537_104922612_RR CASP4; rs497116
389 ORF188_9_117491884_117500665_117513941_117521837_RR ASTN2; rs2771051
390 ORF188_9_117491884_117500665_117513941_117521837_RR ASTN2; rs2771051
391 ORF19_1_177028175_177032504_177116397_177122010_RR ASTN1; rs2861887; rs228014
392 ORF19_1_177028175_177032504_177116397_177122010_RR ASTN1; rs2861887; rs228014
393 ORF19_1_177129764_177133067_177178719_177181987_FR ASTN1; BRINP2; rs2861887
394 ORF19_1_177129764_177133067_177178719_177181987_FR ASTN1; BRINP2; rs2861887
395 ORF19_1_76032659_76035831_76083373_76086337_RR ST6GALNAC3; rs12095069
396 ORF19_1_76032659_76035831_76083373_76086337_RR ST6GALNAC3; rs12095069
397 ORF19_10_76413183_76419817_76444465_76451876_FR C10orf11; rs11593840; rs10509373
398 ORF19_10_76413183_76419817_76444465_76451876_FR C10orf11; rs11593840; rs10509373
399 ORF19_15_59205508_59210997_59259334_59261999_RR LDHAL6B; MYO1E; rs7165001; rs387906807; rs2306786
400 ORF19_15_59205508_59210997_59259334_59261999_RR LDHAL6B; MYO1E; rs7165001; rs387906807; rs2306786
401 ORF19_18_35655009_35656946_35676499_35681362_RR GALNT1; rs17647532
402 ORF19_18_35655009_35656946_35676499_35681362_RR GALNT1; rs17647532
403 ORF19_2_106158642_106160954_106220910_106222156_FF C2orf40; UXS1; rs6738485
404 ORF19_2_106158642_106160954_106220910_106222156_FF C2orf40; UXS1; rs6738485
405 ORF19_2_20261188_20263397_20361646_20369312_FF PUM2; rs111612372
406 ORF19_2_20261188_20263397_20361646_20369312_FF PUM2; rs111612372
407 ORF19_2_217551078_217557187_217605412_217608263_RR DIRC3; rs6435999
408 ORF19_2_217551078_217557187_217605412_217608263_RR DIRC3; rs6435999
409 ORF19_20_11126224_11127995_11191868_11199236_FR rs6040399; rs77790871
410 ORF19_20_11126224_11127995_11191868_11199236_FR rs6040399; rs77790871
411 ORF19_4_125340607_125343598_125382298_125392915_FR FAT4; rs1039808
412 ORF19_4_125340607_125343598_125382298_125392915_FR FAT4; rs1039808
413 ORF19_6_5723608_5725733_5745537_5748323_RR FARS2; rs775690041
414 ORF19_6_5723608_5725733_5745537_5748323_RR FARS2; rs775690041
415 ORF191_13_45859224_45860475_45923601_45927773_RR SIAH3; ZC3H13
416 ORF191_13_45859224_45860475_45923601_45927773_RR SIAH3; ZC3H13
417 ORF191_13_74443077_74451062_74472806_74486278_FR rs17714988; rs17718828
418 ORF191_13_74443077_74451062_74472806_74486278_FR rs17714988; rs17718828
419 ORF193_1_66143825_66151966_66218811_66223865_FR PDE4B; rs490094; rs10454453; rs486438; rs567279; rs6588190
420 ORF193_1_66143825_66151966_66218811_66223865_FR PDE4B; rs490094; rs10454453; rs486438; rs567279; rs6588190
421 ORF194_13_74472806_74486278_74508577_74514808_RF rs17714988; rs17718828
422 ORF194_13_74472806_74486278_74508577_74514808_RF rs17714988; rs17718828
423 ORF194_2_19641438_19647635_19660555_19664933_RF rs10856789; rs16986953
424 ORF194_2_19641438_19647635_19660555_19664933_RF rs10856789; rs16986953
425 ORF194_6_27448356_27449458_27517801_27518934_FF ZNF184; rs34196306; rs149866169; rs34864796; rs16867808; rs2205829; rs13195040
426 ORF194_6_27448356_27449458_27517801_27518934_FF ZNF184; rs34196306; rs149866169; rs34864796; rs16867808; rs2205829; rs13195040
427 ORF194_9_105414393_105415801_105438651_105443203_FF FSD1L; SLC44A1
428 ORF194_9_105414393_105415801_105438651_105443203_FF FSD1L; SLC44A1
429 ORF195_2_161568697_161570567_161580634_161587484_RF SLC4A10; rs56037433
430 ORF195_2_161568697_161570567_161580634_161587484_RF SLC4A10; rs56037433
431 ORF196_6_84687731_84692812_84775145_84786636_RF TBX18; rs760905589; rs869320679; rs797045022; rs77693245; rs72912698
432 ORF196_6_84687731_84692812_84775145_84786636_RF TBX18; rs760905589; rs869320679; rs797045022; rs77693245; rs72912698
433 ORF197_7_107251976_107254546_107284754_107287455_FR COG5; rs773281248; rs3815148
434 ORF197_7_107251976_107254546_107284754_107287455_FR COG5; rs773281248; rs3815148
435 ORF198_8_119154139_119162140_119209458_119214583_RR MAL2; rs2468186; rs1425053; rs6989684
436 ORF198_8_119154139_119162140_119209458_119214583_RR MAL2; rs2468186; rs1425053; rs6989684
表3.d1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
331 93; 58; NA 1; 5; 1; 1; NA 0.093070545; 0.156450038; 0.234279681; 0.210195578; NA
332 93; 58; NA 1; 5; 1; 1; NA 0.093070545; 0.156450038; 0.234279681; 0.210195578; NA
333 NA NA NA
334 NA NA NA
335 28; 32; 32 3; 4; 3; 4; 3; 4 0.071800115; 0.02285211; 0.09275567; 0.033810966; 0.09275567; 0.033810966
336 28; 32; 32 3; 4; 3; 4; 3; 4 0.071800115; 0.02285211; 0.09275567; 0.033810966; 0.09275567; 0.033810966
337 20; 10; 30; 30; 16; NA 1; 1; 1; 1; 1; 1; 1; 1; 1; 1; NA 0.366490901; 0.372098641; 0.272678156; 0.285987033; 0.36936157; 0.363021342; 0.36936157; 0.363021342; 0.343724359; 0.353547066; NA
338 20; 10; 30; 30; 16; NA 1; 1; 1; 1; 1; 1; 1; 1; 1; 1; NA 0.366490901; 0.372098641; 0.272678156; 0.285987033; 0.36936157; 0.363021342; 0.36936157; 0.363021342; 0.343724359; 0.353547066; NA
339 29; NA 2; 2; NA 0.211050406; 0.22548219; NA
340 29; NA 2; 2; NA 0.211050406; 0.22548219; NA
341 NA NA NA
342 NA NA NA
343 3; NA 3; 1; NA 5.91e-05; 0.042102538; NA
344 3; NA 3; 1; NA 5.91e-05; 0.042102538; NA
345 90; NA 3; 3; NA 0.219233776; 0.208104371; NA
346 90; NA 3; 3; NA 0.219233776; 0.208104371; NA
347 190; NA 5; 4; NA 0.112399625; 0.054978865; NA
348 190; NA 5; 4; NA 0.112399625; 0.054978865; NA
349 82; NA 1; 2; NA 0.127264367; 0.188524907; NA
350 82; NA 1; 2; NA 0.127264367; 0.188524907; NA
351 40; NA 2; 3; NA 0.261899069; 0.150241062; NA
352 40; NA 2; 3; NA 0.261899069; 0.150241062; NA
353 40; NA 4; 4; NA 0.096861772; 0.075450093; NA
354 175; NA 4; 4; NA 0.096861772; 0.075450093; NA
355 16; 8; 10 1; 1; 1; 1; 1; 1 0.343724359; 0.353547066; 0.236185646; 0.249326315; 0.272678156; 0.285987033
356 16; 8; 10 1; 1; 1; 1; 1; 1 0.343724359; 0.353547066; 0.236185646; 0.249326315; 0.272678156; 0.285987033
357 48; 15; 43 1; 1; 1; 1; 1; 1 0.288729231; 0.267628012; 0.335307856; 0.346011739; 0.315614698; 0.297350686
358 48; 15; 43 1; 1; 1; 1; 1; 1 0.288729231; 0.267628012; 0.335307856; 0.346011739; 0.315614698; 0.297350686
359 41; NA 1; 2; NA 0.325868449; 0.271883499; NA
360 41; NA 1; 2; NA 0.325868449; 0.271883499; NA
361 46; NA 2; 3; NA 0.273777277; 0.178397403; NA
362 46; NA 2; 3; NA 0.273777277; 0.178397403; NA
363 24; 151; 84; NA 1; 1; 1; 2; 1; 2; NA 0.375122937; 0.375945017; 0.014886343; 0.032692527; 0.120373828; 0.181549809; NA
364 24; 151; 84; NA 1; 1; 1; 2; 1; 2; NA 0.375122937; 0.375945017; 0.014886343; 0.032692527; 0.120373828; 0.181549809; NA
365 19; NA 1; 1; NA 0.362286681; 0.369026848; NA
366 19; NA 1; 1; NA 0.362286681; 0.369026848; NA
367 22 3; 3 0.042821316; 0.050708849
368 22 3; 3 0.042821316; 0.050708849
369 41; NA 2; 2; NA 0.26460109; 0.271883499; NA
370 41; NA 2; 2; NA 0.26460109; 0.271883499; NA
371 37; 22; 52; NA 1; 1; 1; 1; 1; 1; NA 0.34481748; 0.331269672; 0.372324987; 0.375573766; 0.266738689; 0.244043749; NA
372 37; 22; 52; NA 1; 1; 1; 1; 1; 1; NA 0.34481748; 0.331269672; 0.372324987; 0.375573766; 0.266738689; 0.244043749; NA
373 35; NA 4; 2; NA 0.035189793; 0.255336195; NA
374 35; NA 4; 2; NA 0.035189793; 0.255336195; NA
375 37; NA 1; 1; NA 0.34481748; 0.331269672; NA
376 37; NA 1; 1; NA 0.34481748; 0.331269672; NA
377 13 1; 1 0.314642613; 0.32680192
378 13 1; 1 0.314642613; 0.32680192
379 NA NA NA
380 NA NA NA
381 18; NA 3; 3; NA 0.026589963; 0.031898647; NA
382 18; NA 3; 3; NA 0.026589963; 0.031898647; NA
383 135; NA 4; 2; NA 0.167299602; 0.052146884; NA
384 135; NA 4; 2; NA 0.167299602; 0.052146884; NA
385 29; NA 2; 2; NA 0.211050406; 0.22548219; NA
386 29; NA 2; 2; NA 0.211050406; 0.22548219; NA
387 18; NA 1; 1; NA 0.357137933; 0.364965787; NA
388 18; NA 1; 1; NA 0.357137933; 0.364965787; NA
389 24; NA 1; 1; NA 0.375122937; 0.375945017; NA
390 24; NA 1; 1; NA 0.375122937; 0.375945017; NA
391 107; NA 2; 3; NA 0.132213333; 0.169050538; NA
392 107; NA 2; 3; NA 0.132213333; 0.169050538; NA
393 107; 123; NA 2; 3; 1; 1; NA 0.132213333; 0.169050538; 0.037152217; 0.02695001; NA
394 107; 123; NA 2; 3; 1; 1; NA 0.132213333; 0.169050538; 0.037152217; 0.02695001; NA
395 45; NA 5; 5; NA 0.022343156; 0.028833151; NA
396 45; NA 5; 5; NA 0.022343156; 0.028833151; NA
397 76; NA 4; 4; NA 0.169506823; 0.182516854; NA
398 76; NA 4; 4; NA 0.169506823; 0.182516854; NA
399 30; 45; NA 1; 1; 1; 2; NA 0.36936157; 0.363021342; 0.305019886; 0.276375861; NA
400 30; 45; NA 1; 1; 1; 2; NA 0.36936157; 0.363021342; 0.305019886; 0.276375861; NA
401 10; NA 1; 1; NA 0.272678156; 0.285987033; NA
402 10; NA 1; 1; NA 0.272678156; 0.285987033; NA
403 10; 10; NA 1; 1; 1; 1; NA 0.272678156; 0.285987033; 0.272678156; 0.285987033; NA
404 10; 10; NA 1; 1; 1; 1; NA 0.272678156; 0.285987033; 0.272678156; 0.285987033; NA
405 54; NA 5; 6; NA 0.040491239; 0.018151611; NA
406 54; NA 5; 6; NA 0.040491239; 0.018151611; NA
407 26; NA 1; 1; NA 0.375314357; 0.373699919; NA
408 26; NA 1; 1; NA 0.375314357; 0.373699919; NA
409 NA NA NA
410 NA NA NA
411 19; NA 3; 4; NA 0.030348034; 0.006361707; NA
412 19; NA 3; 4; NA 0.030348034; 0.006361707; NA
413 37; NA 1; 2; NA 0.34481748; 0.262259643; NA
414 37; NA 1; 2; NA 0.34481748; 0.262259643; NA
415 56; 50 3; 2; 3; 3 0.199907871; 0.267835203; 0.179388457; 0.193973801
416 56; 50 3; 2; 3; 3 0.199907871; 0.267835203; 0.179388457; 0.193973801
417 NA NA NA
418 NA NA NA
419 17; NA 3; 2; NA 0.023054538; 0.126473611; NA
420 17; NA 3; 2; NA 0.023054538; 0.126473611; NA
421 NA NA NA
422 NA NA NA
423 NA NA NA
424 NA NA NA
425 42; NA 1; 1; NA 0.320791853; 0.303213711; NA
426 42; NA 1; 1; NA 0.320791853; 0.303213711; NA
427 18; 18 2; 2; 2; 2 0.123103064; 0.136301816; 0.123103064; 0.136301816
428 18; 18 2; 2; 2; 2 0.123103064; 0.136301816; 0.123103064; 0.136301816
429 6; NA 1; 1; NA 0.191789359; 0.203777963; NA
430 6; NA 1; 1; NA 0.191789359; 0.203777963; NA
431 20; NA 4; 5; NA 0.005899409; 0.001067155; NA
432 20; NA 4; 5; NA 0.005899409; 0.001067155; NA
433 9; NA 1; 1; NA 0.255358235; 0.268692312; NA
434 9; NA 1; 1; NA 0.255358235; 0.268692312; NA
435 9; NA 1; 1; NA 0.255358235; 0.268692312; NA
436 9; NA 1; 1; NA 0.255358235; 0.268692312; NA
表3.d2
   FDR_HyperG Percent_Sig logFC AveExpr
331 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.08; 5.38; 1.72; 1.72; NA -0.921517398 -0.921517398
332 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.08; 5.38; 1.72; 1.72; NA -0.725657547 -0.725657547
333 NA NA -0.948082367 -0.948082367
334 NA NA -0.750194193 -0.750194193
335 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.71; 14.29; 9.38; 12.5; 9.38; 12.5 -0.850894358 -0.850894358
336 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.71; 14.29; 9.38; 12.5; 9.38; 12.5 -0.801014332 -0.801014332
337 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 5; 5; 10; 10; 3.33; 3.33; 3.33; 3.33; 6.25; 6.25; NA -0.960853701 -0.960853701
338 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 5; 5; 10; 10; 3.33; 3.33; 3.33; 3.33; 6.25; 6.25; NA -0.874141303 -0.874141303
339 0.375519541; 0.376115439; NA 6.9; 6.9; NA -0.809068755 -0.809068755
340 0.375519541; 0.376115439; NA 6.9; 6.9; NA -0.723853684 -0.723853684
341 NA NA -0.944150717 -0.944150717
342 NA NA -0.934437678 -0.934437678
343 0.007721092; 0.376115439; NA 100; 100; NA -0.97589875 -0.97589875
344 0.007721092; 0.376115439; NA 100; 100; NA -0.816938357 -0.816938357
345 0.375519541; 0.376115439; NA 3.33; 3.33; NA -0.976072431 -0.976072431
346 0.375519541; 0.376115439; NA 3.33; 3.33; NA -0.828664635 -0.828664635
347 0.375519541; 0.376115439; NA 2.63; 2.11; NA -0.814276361 -0.814276361
348 0.375519541; 0.376115439; NA 2.63; 2.11; NA -0.749839806 -0.749839806
349 0.375519541; 0.376115439; NA 1.22; 2.44; NA -0.840481458 -0.840481458
350 0.375519541; 0.376115439; NA 1.22; 2.44; NA -0.716930671 -0.716930671
351 0.375519541; 0.376115439; NA 5; 7.5; NA -0.831695631 -0.831695631
352 0.375519541; 0.376115439; NA 5; 7.5; NA -0.719687367 -0.719687367
353 0.375519541; 0.376115439; NA 2.29; 2.29; NA -0.871100048 -0.871100048
354 0.375519541; 0.376115439; NA 2.29; 2.29; NA -0.824196562 -0.824196562
355 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.25; 6.25; 12.5; 12.5; 10; 10 -0.865767376 -0.865767376
356 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.25; 6.25; 12.5; 12.5; 10; 10 -0.622209536 -0.622209536
357 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.08; 2.08; 6.67; 6.67; 2.33; 2.33 -0.805969028 -0.805969028
358 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.08; 2.08; 6.67; 6.67; 2.33; 2.33 -0.797581866 -0.797581866
359 0.375519541; 0.376115439; NA 2.44; 4.88; NA -1.195123917 -1.195123917
360 0.375519541; 0.376115439; NA 2.44; 4.88; NA -0.954148183 -0.954148183
361 0.375519541; 0.376115439; NA 4.35; 6.52; NA -1.309738674 -1.309738674
362 0.375519541; 0.376115439; NA 4.35; 6.52; NA -1.117933554 -1.117933554
363 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4.17; 4.17; 0.66; 1.32; 1.19; 2.38; NA -1.145854871 -1.145854871
364 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 4.17; 4.17; 0.66; 1.32; 1.19; 2.38; NA -0.885683435 -0.885683435
365 0.375519541; 0.376115439; NA 5.26; 5.26; NA -0.978351767 -0.978351767
366 0.375519541; 0.376115439; NA 5.26; 5.26; NA -0.967332961 -0.967332961
367 0.375519541; 0.376115439 13.64; 13.64 -0.80694846 -0.80694846
368 0.375519541; 0.376115439 13.64; 13.64 -0.806365294 -0.806365294
369 0.375519541; 0.376115439; NA 4.88; 4.88; NA -1.286450873 -1.286450873
370 0.375519541; 0.376115439; NA 4.88; 4.88; NA -1.056178341 -1.056178341
371 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.7; 2.7; 4.55; 4.55; 1.92; 1.92; NA -0.776863974 -0.776863974
372 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 2.7; 2.7; 4.55; 4.55; 1.92; 1.92; NA -0.72733579 -0.72733579
373 0.375519541; 0.376115439; NA 11.43; 5.71; NA -1.162595556 -1.162595556
374 0.375519541; 0.376115439; NA 11.43; 5.71; NA -0.876533853 -0.876533853
375 0.375519541; 0.376115439; NA 2.7; 2.7; NA -0.883635438 -0.883635438
376 0.375519541; 0.376115439; NA 2.7; 2.7; NA -0.856646309 -0.856646309
377 0.375519541; 0.376115439 7.69; 7.69 -1.074105112 -1.074105112
378 0.375519541; 0.376115439 7.69; 7.69 -0.976511475 -0.976511475
379 NA NA -1.410088163 -1.410088163
380 NA NA -1.184443144 -1.184443144
381 0.375519541; 0.376115439; NA 16.67; 16.67; NA -0.760380336 -0.760380336
382 0.375519541; 0.376115439; NA 16.67; 16.67; NA -0.675157556 -0.675157556
383 0.375519541; 0.376115439; NA 2.96; 1.48; NA -1.100687073 -1.100687073
384 0.375519541; 0.376115439; NA 2.96; 1.48; NA -0.987623222 -0.987623222
385 0.375519541; 0.376115439; NA 6.9; 6.9; NA -0.870794459 -0.870794459
386 0.375519541; 0.376115439; NA 6.9; 6.9; NA -0.786934947 -0.786934947
387 0.375519541; 0.376115439; NA 5.56; 5.56; NA -1.741773624 -1.741773624
388 0.375519541; 0.376115439; NA 5.56; 5.56; NA -1.382282356 -1.382282356
389 0.375519541; 0.376115439; NA 4.17; 4.17; NA -0.824477534 -0.824477534
390 0.375519541; 0.376115439; NA 4.17; 4.17; NA -0.821261516 -0.821261516
391 0.375519541; 0.376115439; NA 1.87; 2.8; NA -1.391439553 -1.391439553
392 0.375519541; 0.376115439; NA 1.87; 2.8; NA -1.383200123 -1.383200123
393 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.87; 2.8; 0.81; 0.81; NA -1.132100408 -1.132100408
394 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 1.87; 2.8; 0.81; 0.81; NA -0.824499671 -0.824499671
395 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.761615774 -0.761615774
396 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.739590554 -0.739590554
397 0.375519541; 0.376115439; NA 5.26; 5.26; NA -0.886008175 -0.886008175
398 0.375519541; 0.376115439; NA 5.26; 5.26; NA -0.883830596 -0.883830596
399 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 3.33; 3.33; 2.22; 4.44; NA -0.860206751 -0.860206751
400 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 3.33; 3.33; 2.22; 4.44; NA -0.793003257 -0.793003257
401 0.375519541; 0.376115439; NA 10; 10; NA -1.454708376 -1.454708376
402 0.375519541; 0.376115439; NA 10; 10; NA -1.35536412 -1.35536412
403 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 10; 10; 10; 10; NA -1.212349306 -1.212349306
404 0.375519541; 0.376115439; 0.375519541; 0.376115439; NA 10; 10; 10; 10; NA -0.977399348 -0.977399348
405 0.375519541; 0.376115439; NA 9.26; 11.11; NA -0.830681206 -0.830681206
406 0.375519541; 0.376115439; NA 9.26; 11.11; NA -0.779347846 -0.779347846
407 0.375519541; 0.376115439; NA 3.85; 3.85; NA -0.954394932 -0.954394932
408 0.375519541; 0.376115439; NA 3.85; 3.85; NA -0.737879777 -0.737879777
409 NA NA -0.764563519 -0.764563519
410 NA NA -0.719285274 -0.719285274
411 0.375519541; 0.217379602; NA 15.79; 21.05; NA -0.923647913 -0.923647913
412 0.375519541; 0.217379602; NA 15.79; 21.05; NA -0.818636244 -0.818636244
413 0.375519541; 0.376115439; NA 2.7; 5.41; NA -0.792890284 -0.792890284
414 0.375519541; 0.376115439; NA 2.7; 5.41; NA -0.669847039 -0.669847039
415 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.36; 3.57; 6; 6 -0.707394345 -0.707394345
416 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.36; 3.57; 6; 6 -0.636098161 -0.636098161
417 NA NA -0.75301095 -0.75301095
418 NA NA -0.750437096 -0.750437096
419 0.375519541; 0.376115439; NA 17.65; 11.76; NA -1.246894747 -1.246894747
420 0.375519541; 0.376115439; NA 17.65; 11.76; NA -1.140655166 -1.140655166
421 NA NA -0.768554446 -0.768554446
422 NA NA -0.726264736 -0.726264736
423 NA NA -0.754625968 -0.754625968
424 NA NA -0.749243708 -0.749243708
425 0.375519541; 0.376115439; NA 2.38; 2.38; NA -0.926870051 -0.926870051
426 0.375519541; 0.376115439; NA 2.38; 2.38; NA -0.789545602 -0.789545602
427 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 11.11; 11.11; 11.11 -0.863538231 -0.863538231
428 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 11.11; 11.11; 11.11 -0.782442469 -0.782442469
429 0.375519541; 0.376115439; NA 16.67; 16.67; NA -1.306917223 -1.306917223
430 0.375519541; 0.376115439; NA 16.67; 16.67; NA -0.885477066 -0.885477066
431 0.242080288; 0.077749847; NA 20; 25; NA -1.383039898 -1.383039898
432 0.242080288; 0.077749847; NA 20; 25; NA -1.192345027 -1.192345027
433 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.866014897 -0.866014897
434 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.700156781 -0.700156781
435 0.375519541; 0.376115439; NA 11.11; 11.11; NA -1.094031267 -1.094031267
436 0.375519541; 0.376115439; NA 11.11; 11.11; NA -0.954751365 -0.954751365
表3.d3
   t P值 adj.P.Val B FC FC_1 LS
331 -15.40305266 0.00000000293 0.00000154 11.81530228 0.527953437 -1.89410643 -1
332 -9.366959157 0.000000753 0.0000625 6.340097273 0.604721364 -1.653654161 -1
333 -7.924499048 0.00000418 0.0000985 4.535830888 0.518320957 -1.929306515 -1
334 -7.327723864 0.00000941 0.000304305 3.770550192 0.594523527 -1.682019223 -1
335 -8.423915076 0.00000229 0.000124302 5.213300034 0.55444092 -1.803618681 -1
336 -8.797860483 0.00000142 0.0000498 5.647316199 0.573945505 -1.742325693 -1
337 -14.86078107 0.00000000441 0.00000191 11.42163634 0.513752815 -1.946461354 -1
338 -9.012447513 0.00000113 0.00008 5.928125513 0.5455785 -1.832916804 -1
339 -10.88034667 0.000000145 0.0000123 7.968195835 0.570750153 -1.752080127 -1
340 -8.462664777 0.00000218 0.000121119 5.261594474 0.605477945 -1.65158782 -1
341 -14.83737478 0.00000000470 0.00000381 11.31305836 0.519735418 -1.924055903 -1
342 -9.75105331 0.000000476 0.0000252 6.763029365 0.523246377 -1.911145579 -1
343 -9.350813197 0.000000767 0.0000633 6.3216273 0.508423017 -1.966866107 -1
344 -7.238276016 0.0000104 0.000178447 3.596646223 0.567645305 -1.761663475 -1
345 -8.627381661 0.00000179 0.000106929 5.464920678 0.508361813 -1.967102905 -1
346 -9.377568034 0.000000723 0.0000328 6.337279031 0.563050163 -1.77604069 -1
347 -10.92714789 0.000000138 0.0000119 8.01564252 0.568693665 -1.75841593 -1
348 -11.66749678 0.0000000697 0.0000149 8.714938486 0.594669585 -1.681606098 -1
349 -6.725119536 0.0000218 0.000527416 2.91058998 0.558457169 -1.790647619 -1
350 -8.417963034 0.00000225 0.0000664 5.174881341 0.608390415 -1.643681386 -1
351 -7.798126044 0.00000493 0.000109597 4.367383638 0.561868478 -1.779775943 -1
352 -6.458094521 0.000032 0.000679711 2.513485908 0.607229015 -1.646825127 -1
353 -9.317708714 0.000000773 0.0000341 6.267704571 0.546729813 -1.829057016 -1
354 -5.765464828 0.0000913 0.001371991 1.436267598 0.564796651 -1.770548743 -1
355 -6.610521224 0.0000252 0.000320602 2.682915278 0.548754444 -1.822308703 -1
356 -6.447663022 0.0000325 0.000687266 2.497769064 0.649675166 -1.53923076 -1
357 -10.00139577 0.000000374 0.0000406 7.044594598 0.571977766 -1.748319707 -1
358 -6.56128376 0.000027 0.000335173 2.608960326 0.575312665 -1.738185271 -1
359 -12.93839332 0.0000000212 0.00000424 9.889431513 0.436748933 -2.289644976 -1
360 -5.539746777 0.000130349 0.001755359 1.070421991 0.51614625 -1.937435367 -1
361 -9.124465847 0.000000966 0.0000393 6.040509148 0.403393943 -2.478966326 -1
362 -8.113656673 0.00000337 0.000159 4.820149231 0.460753314 -2.170358781 -1
363 -9.602174961 0.000000561 0.0000279 6.595022534 0.451921822 -2.2127721 -1
364 -6.211434533 0.0000462 0.000864536 2.13771615 0.541231069 -1.84763968 -1
365 -7.945343066 0.00000417 0.000181804 4.601958934 0.507559279 -1.970213216 -1
366 -8.920526194 0.00000123 0.0000453 5.796368649 0.511450683 -1.955222728 -1
367 -5.664222474 0.000105502 0.000859592 1.201847513 0.571589587 -1.749507028 -1
368 -6.019381984 0.0000617 0.00105455 1.839131872 0.571820682 -1.748799985 -1
369 -8.186336569 0.000003 0.0000795 4.878574428 0.409958315 -2.439272393 -1
370 -8.391287289 0.00000238 0.000127589 5.172497759 0.480904276 -2.079415905 -1
371 -5.802787464 0.0000849 0.000736707 1.426626085 0.583634077 -1.713402352 -1
372 -6.840270684 0.0000185 0.000472936 3.078761597 0.604018319 -1.655578926 -1
373 -8.389658931 0.00000233 0.000068 5.139014356 0.446708138 -2.238598123 -1
374 -7.098993093 0.0000129 0.000370933 3.449949473 0.544674468 -1.835959014 -1
375 -8.511476381 0.00000206 0.000117189 5.32217773 0.541999927 -1.845018699 -1
376 -8.697227788 0.0000016 0.0000538 5.523777223 0.552234793 -1.81082397 -1
377 -9.274493187 0.000000813 0.0000352 6.217240808 0.474965585 -2.1054157 -1
378 -7.538755108 0.00000709 0.000252002 4.060177366 0.508207131 -1.967701629 -1
379 -12.59563615 0.0000000286 0.00000499 9.591402294 0.376288691 -2.657534025 -1
380 -8.007170567 0.00000385 0.000173555 4.682515277 0.439994335 -2.272756532 -1
381 -6.261573955 0.0000421 0.000451254 2.151478857 0.59034068 -1.693937136 -1
382 -7.06012912 0.0000136 0.000385073 3.394774996 0.626263822 -1.596771145 -1
383 -13.29060371 0.0000000156 0.0000036 10.18738114 0.466294374 -2.144568016 -1
384 -11.71837636 0.0000000664 0.0000146 8.762229559 0.504307916 -1.982915531 -1
385 -8.699104077 0.0000016 0.0000538 5.526091072 0.546845633 -1.828669629 -1
386 -6.987570347 0.000015 0.000411493 3.291214664 0.579574109 -1.725404886 -1
387 -11.89064726 0.0000000544 0.00000695 8.951957865 0.299001862 -3.344460773 -1
388 -8.148200887 0.00000322 0.000155051 4.86449863 0.383611438 -2.606804438 -1
389 -9.939988583 0.000000387 0.000022 6.973059432 0.564686664 -1.7708936 -1
390 -16.31897469 0.00000000159 0.00000231 12.32275984 0.565946853 -1.766950368 -1
391 -14.73023458 0.00000000511 0.00000399 11.23554538 0.381184258 -2.623403192 -1
392 -10.76685913 0.000000163 0.0000132 7.852351576 0.383367483 -2.608463277 -1
393 -9.001437397 0.00000111 0.0000428 5.893772979 0.456250989 -2.19177607 -1
394 -13.1266406 0.0000000188 0.00000773 9.994070622 0.564678 -1.770920773 -1
395 -8.592262337 0.00000182 0.000058 5.39369419 0.589835363 -1.695388345 -1
396 -5.636215916 0.000111856 0.001575755 1.227665611 0.598909302 -1.6697019 -1
397 -7.442856385 0.00000788 0.000148151 3.882997345 0.541109256 -1.848055617 -1
398 -6.5146902 0.0000295 0.000643701 2.598489023 0.541926614 -1.845268298 -1
399 -9.313121571 0.000000778 0.0000342 6.262357406 0.550873607 -1.81529844 -1
400 -8.951860382 0.00000122 0.000084 5.856347602 0.577141406 -1.732677624 -1
401 -19.21058447 0.000000000242 0.00000103 14.00538346 0.364828824 -2.741011491 -1
402 -10.35207487 0.000000249 0.000017 7.419189894 0.390836167 -2.558616846 -1
403 -9.420559347 0.000000688 0.0000317 6.387016549 0.431565276 -2.317146574 -1
404 -7.34927411 0.00000914 0.000299369 3.800395741 0.507894463 -1.968912977 -1
405 -8.135101066 0.00000328 0.000156625 4.847697669 0.562263692 -1.778524941 -1
406 -7.167978811 0.0000115 0.000189997 3.496974511 0.582630105 -1.716354838 -1
407 -5.647095069 0.000108398 0.000876327 1.173875764 0.51605798 -1.937766762 -1
408 -9.948646591 0.000000396 0.0000421 6.987562272 0.599619922 -1.667723107 -1
409 -6.678889502 0.0000232 0.000549313 2.842554814 0.588631429 -1.698855939 -1
410 -8.798340421 0.00000142 0.0000498 5.64790265 0.607398279 -1.646366205 -1
411 -9.633171566 0.000000542 0.0000273 6.630186096 0.527174352 -1.896905637 -1
412 -7.625820949 0.00000632 0.000234604 4.177973912 0.566977644 -1.763737971 -1
413 -8.328467386 0.00000251 0.0000711 5.061149746 0.577186602 -1.732541949 -1
414 -7.372989295 0.00000885 0.000292859 3.833168439 0.628573328 -1.590904283 -1
415 -8.376149411 0.00000237 0.0000687 5.121861864 0.612425243 -1.632852353 -1
416 -8.494173232 0.0000021 0.000118596 5.300733663 0.643450842 -1.554120277 -1
417 -10.81838874 0.00000016 0.0000245 7.894287104 0.593363895 -1.68530645 -1
418 -6.573551886 0.0000266 0.000331965 2.627418687 0.594423437 -1.682302443 -1
419 -9.78105613 0.00000046 0.0000246 6.796617881 0.421354154 -2.373300444 -1
420 -9.48944746 0.000000656 0.0000573 6.479323239 0.45355356 -2.204811267 -1
421 -5.906497953 0.0000723 0.000659575 1.593088987 0.587005348 -1.703561991 -1
422 -8.231092072 0.00000291 0.000144892 4.970325116 0.604466908 -1.654350284 -1
423 -11.95634939 0.0000000532 0.0000131 8.980718944 0.592700028 -1.687194115 -1
424 -10.07876027 0.000000333 0.0000202 7.12510324 0.594915343 -1.680911429 -1
425 -13.1013229 0.0000000192 0.0000078 9.973166353 0.525998266 -1.901146952 -1
426 -16.0269123 0.00000000186 0.00000125 12.24943861 0.578526279 -1.728529951 -1
427 -9.498218589 0.00000063 0.0000299 6.476375657 0.549602994 -1.819495182 -1
428 -7.87680822 0.00000456 0.000192251 4.512105855 0.581381686 -1.720040421 -1
429 -7.749405893 0.00000525 0.000114307 4.301908322 0.404183624 -2.474122996 -1
430 -4.649862578 0.000568463 0.004918258 -0.440168038 0.541308495 -1.847375405 -1
431 -8.641616342 0.00000171 0.0000561 5.45501507 0.383410062 -2.608173598 -1
432 -7.56693837 0.00000683 0.000246294 4.098415764 0.437591 -2.285238954 -1
433 -5.474015475 0.000142842 0.001066198 0.888902787 0.548660304 -1.822621381 -1
434 -7.171450122 0.0000116 0.000347783 3.552269482 0.615505315 -1.624681341 -1
435 -5.093577314 0.000265883 0.001674094 0.247995619 0.468450571 -2.134696939 -1
436 -10.00240574 0.000000374 0.0000405 7.045683917 0.515930498 -1.938245566 -1
表3.d4
      探針序列 探針位置
偵測到之環 60 mer Chr
331 sAD ATCAGGTCATATATCTCACAGAGAACATTCGACCATGAGCTCTCTGATACCTACGGTTGT 1
332 mAD ATCAGGTCATATATCTCACAGAGAACATTCGACCATGAGCTCTCTGATACCTACGGTTGT 1
333 sAD AAAATAGCTACCTATGTAATAGAGAACATCGAAAATGGGTTCTGTTTCAAATACATGGAA 14
334 mAD AAAATAGCTACCTATGTAATAGAGAACATCGAAAATGGGTTCTGTTTCAAATACATGGAA 14
335 mAD TTTTTAAAGAAGGTTTGTATCATATTTCTCGAAGAGTGGCATGCTTTTCCCAAATGTCAC 19
336 sAD TTTTTAAAGAAGGTTTGTATCATATTTCTCGAAGAGTGGCATGCTTTTCCCAAATGTCAC 19
337 sAD ACATATACACTCATTCTCAAAATCTTTCTCGACTGAATTGGAATACATATACATGCAGGT 20
338 mAD ACATATACACTCATTCTCAAAATCTTTCTCGACTGAATTGGAATACATATACATGCAGGT 20
339 sAD TAAACTATCTGTTACCAGTCCGTCTCTTTCGAAATATGAATCATCTTTGTCCAGTATGGA 13
340 mAD TAAACTATCTGTTACCAGTCCGTCTCTTTCGAAATATGAATCATCTTTGTCCAGTATGGA 13
341 mAD GAAAAAATAGTTATGGAAGTTGAGAACATCGAAAATAAAGACCGAAAGAAATGAGGATAT 6
342 sAD GAAAAAATAGTTATGGAAGTTGAGAACATCGAAAATAAAGACCGAAAGAAATGAGGATAT 6
343 mAD ATATTTTACAATTTTTTAGGTCAAGAATTCGATTTGCTATTTGGAGAGCAATGAAACTGA X
344 sAD ATATTTTACAATTTTTTAGGTCAAGAATTCGATTTGCTATTTGGAGAGCAATGAAACTGA X
345 mAD TATTACAGAAAAAAAAAAATGGATCTCTTCGAAGCATGTATAATTTATTTTAGGAATATG 5
346 sAD TATTACAGAAAAAAAAAAATGGATCTCTTCGAAGCATGTATAATTTATTTTAGGAATATG 5
347 sAD ATGTATTTTTCACAATATGAATTAAAAGTCGATGTTTCAAGTTATGTCATAGGATTTCAA 10
348 mAD ATGTATTTTTCACAATATGAATTAAAAGTCGATGTTTCAAGTTATGTCATAGGATTTCAA 10
349 mAD TTTTCTTTTAAAGGGGAAAATGACAAACTCGAACTTCCTGAATATTTCTGTGATTTAAAT 18
350 sAD TTTTCTTTTAAAGGGGAAAATGACAAACTCGAACTTCCTGAATATTTCTGTGATTTAAAT 18
351 sAD CGTAATAGTTTGATAATTTTATTACTACTCGAGCAAAAGCTTACTTTTTCAGAAAAGAAA 2
352 mAD CGTAATAGTTTGATAATTTTATTACTACTCGAGCAAAAGCTTACTTTTTCAGAAAAGAAA 2
353 sAD GCACTTGTGCACTTACAATCTCCTGTCTTCGAACAGAAATTCCTTTTCATATTTTCAAAA 20
354 mAD GCACTTGTGCACTTACAATCTCCTGTCTTCGAACAGAAATTCCTTTTCATATTTTCAAAA 20
355 sAD TTCATTCTTTATAAACAGGATAAAACAGTCGAAGGAATTCATACCTAGTGACAGACAAGC 21
356 mAD TTCATTCTTTATAAACAGGATAAAACAGTCGAAGGAATTCATACCTAGTGACAGACAAGC 21
357 mAD ACAGAATTATGAAAAAAAAAAAACAAATTCGAATCCTGTTGGAGACATGATGTCATCCCC 3
358 sAD ACAGAATTATGAAAAAAAAAAAACAAATTCGAATCCTGTTGGAGACATGATGTCATCCCC 3
359 sAD GCATTTTTATGAAATTAAATGTCCGTATTCGATTCTCAACCTCTTGCTTAGGTACACACA 3
360 mAD GCATTTTTATGAAATTAAATGTCCGTATTCGATTCTCAACCTCTTGCTTAGGTACACACA 3
361 sAD TGGAATTTTAGATGGAAATTTAATAACTTCGAAAACTAAAACTGGATCCCTATCTCAGGC 6
362 mAD TGGAATTTTAGATGGAAATTTAATAACTTCGAAAACTAAAACTGGATCCCTATCTCAGGC 6
363 sAD AAAACAATTAACAATGAACACGGGAATATCGAGTAGAGTATAAAGGATTTGTGGGAAATA 3
364 mAD AAAACAATTAACAATGAACACGGGAATATCGAGTAGAGTATAAAGGATTTGTGGGAAATA 3
365 mAD ATGAAATAGTGTAATAGAGAAACTTTAGTCGAGTAACGCTGACTTCCTCTGAGTCTCTCC 4
366 sAD ATGAAATAGTGTAATAGAGAAACTTTAGTCGAGTAACGCTGACTTCCTCTGAGTCTCTCC 4
367 sAD GAGCCAATACAATAAATATTTTTTTAAGTCGAAGATAGATATAGACACCCTGTACTGTTT 11
368 mAD GAGCCAATACAATAAATATTTTTTTAAGTCGAAGATAGATATAGACACCCTGTACTGTTT 11
369 sAD GTTAAGAGGTTTTAAAAATAGAAACACATCGAGAAATGATAGAGAGGTTACTAGGAAAGT 1
370 mAD GTTAAGAGGTTTTAAAAATAGAAACACATCGAGAAATGATAGAGAGGTTACTAGGAAAGT 1
371 sAD TAAATAAATAAGTATAAAAATAAATCAATCGAGAGCCAGATATTTTTGTAGTTTTTATGC 15
372 mAD TAAATAAATAAGTATAAAAATAAATCAATCGAGAGCCAGATATTTTTGTAGTTTTTATGC 15
373 sAD CATTACATTTCATAATTTTCTGAAACCCTCGAGAAATGTTCCTTTATATAAGAAAAGCGA 2
374 mAD CATTACATTTCATAATTTTCTGAAACCCTCGAGAAATGTTCCTTTATATAAGAAAAGCGA 2
375 mAD AGTTTTTTAATCTTTCCATTTTTTCTTTTCGACTGTCACCAGTATCATCCCTTCACTTTC 21
376 sAD AGTTTTTTAATCTTTCCATTTTTTCTTTTCGACTGTCACCAGTATCATCCCTTCACTTTC 21
377 sAD ATTTCAAGAGAGATATGCTAACCCTATTTCGATGTACCATTCCTTCCCTACTCTGAATGT Y
378 mAD ATTTCAAGAGAGATATGCTAACCCTATTTCGATGTACCATTCCTTCCCTACTCTGAATGT Y
379 sAD CAAGAAGAAGGGATAAAATACTACTTCTTCGATCAAAGGAAAAAGAAAGAAACCAAACCT 2
380 mAD CAAGAAGAAGGGATAAAATACTACTTCTTCGATCAAAGGAAAAAGAAAGAAACCAAACCT 2
381 sAD TGAAGGTTAGATTTTCTTAATAACATTTTCGATTACTGAAGAGTCCATTAGAGTAAGCAG 6
382 mAD TGAAGGTTAGATTTTCTTAATAACATTTTCGATTACTGAAGAGTCCATTAGAGTAAGCAG 6
383 sAD GTCTTTAGTTAGTAACTTTTCTGGCATATCGAAGTTCAAATATGATGTCCCTCTGAGCCT 7
384 mAD GTCTTTAGTTAGTAACTTTTCTGGCATATCGAAGTTCAAATATGATGTCCCTCTGAGCCT 7
385 sAD TTTTATGAAAGAGAGTGGATTTTTTTTTTCGAAATGGAAAGTAGGTTTGGGTTCATCTCT 8
386 mAD TTTTATGAAAGAGAGTGGATTTTTTTTTTCGAAATGGAAAGTAGGTTTGGGTTCATCTCT 8
387 sAD TCTTTTTTAGACAACTGTTTATTAGCAGTCGAGGGATATTTATTAATTATATTCTAAATC 11
388 mAD TCTTTTTTAGACAACTGTTTATTAGCAGTCGAGGGATATTTATTAATTATATTCTAAATC 11
389 sAD ACTTATCTTTCCAACTTTTATTTTGGATTCGAGTTTCCTTTAATCCCAAAGACACTTGGG 9
390 mAD ACTTATCTTTCCAACTTTTATTTTGGATTCGAGTTTCCTTTAATCCCAAAGACACTTGGG 9
391 mAD GAAAAATCCATGGTAATGAATTAGTTTCTCGAAATACTTTTTCTATACTATGGACAACAA 1
392 sAD GAAAAATCCATGGTAATGAATTAGTTTCTCGAAATACTTTTTCTATACTATGGACAACAA 1
393 sAD AGATAGCCTTTAAAGTAGCTCTAATATTTCGAAGACATACTTCTCTGAAAATACTTATTG 1
394 mAD AGATAGCCTTTAAAGTAGCTCTAATATTTCGAAGACATACTTCTCTGAAAATACTTATTG 1
395 sAD AACCTCTTGGCATTTCTCTTATCAAGATTCGAAAGAAAGAGAAGTGAAAGTCTCTCTTTG 1
396 mAD AACCTCTTGGCATTTCTCTTATCAAGATTCGAAAGAAAGAGAAGTGAAAGTCTCTCTTTG 1
397 sAD TATTGAGTTTTAAGTGTTTTGTATATTTTCGATACTGGGTTCAAATCTCAATTTTATTTT 10
398 mAD TATTGAGTTTTAAGTGTTTTGTATATTTTCGATACTGGGTTCAAATCTCAATTTTATTTT 10
399 sAD CAATTAATTACATTTTGTTCAATGAAATTCGATTATGTCACATGTAACATGAGTGATTCC 15
400 mAD CAATTAATTACATTTTGTTCAATGAAATTCGATTATGTCACATGTAACATGAGTGATTCC 15
401 mAD TAACTACACTAAATATTGAACACAAAAATCGATAAGAAGTTACTTCAACAGCTTCAGAAG 18
402 sAD TAACTACACTAAATATTGAACACAAAAATCGATAAGAAGTTACTTCAACAGCTTCAGAAG 18
403 sAD AAAAAACTATCTTATACTCCTCACTTCTTCGAATTCTATATTCCCCATTTAAAAGACTAC 2
404 mAD AAAAAACTATCTTATACTCCTCACTTCTTCGAATTCTATATTCCCCATTTAAAAGACTAC 2
405 mAD TAAATAGACTGGAAGTGCTTGAAGCACTTCGAACAAATCCTTTTCACCCATTAATCAAGA 2
406 sAD TAAATAGACTGGAAGTGCTTGAAGCACTTCGAACAAATCCTTTTCACCCATTAATCAAGA 2
407 sAD TCTATATATTCTTTTCTTCCTCTTAAAATCGATATGAACCTGAGATGGAAGTTCCTGGAG 2
408 mAD TCTATATATTCTTTTCTTCCTCTTAAAATCGATATGAACCTGAGATGGAAGTTCCTGGAG 2
409 mAD TGTCATTTTTGTGACAGCAAATTCATCTTCGACTGTGAAAGACGTGGAAGTATTTTTCTC 20
410 sAD TGTCATTTTTGTGACAGCAAATTCATCTTCGACTGTGAAAGACGTGGAAGTATTTTTCTC 20
411 sAD TTTTGAACACATTTTTAAAACTCTGAGTTCGATCATAAGACTTGAAAGTTTAGATTACTC 4
412 mAD TTTTGAACACATTTTTAAAACTCTGAGTTCGATCATAAGACTTGAAAGTTTAGATTACTC 4
413 sAD CCAGTTACATAAAGAAAGGAAAAATGGATCGATGAGTCTTTTTTATTTTGAGACAGGGTC 6
414 mAD CCAGTTACATAAAGAAAGGAAAAATGGATCGATGAGTCTTTTTTATTTTGAGACAGGGTC 6
415 sAD GCTATTCAAATAAACATGTATTCCTCATTCGACCTTCAGAAGCTCTGGTTTCATCATCCA 13
416 mAD GCTATTCAAATAAACATGTATTCCTCATTCGACCTTCAGAAGCTCTGGTTTCATCATCCA 13
417 mAD ACGTTTTAATATCTCAAGATTATGAGATTCGAAAGCTCTTCTAGATAGTTGTTATTGGCT 13
418 sAD ACGTTTTAATATCTCAAGATTATGAGATTCGAAAGCTCTTCTAGATAGTTGTTATTGGCT 13
419 sAD ACACTGAGAAACACTCATTGAAGTTAACTCGATAGAGTTAAATACATTTTGGTTGGATGG 1
420 mAD ACACTGAGAAACACTCATTGAAGTTAACTCGATAGAGTTAAATACATTTTGGTTGGATGG 1
421 sAD GTCTTGTTAATCTGAATGTTATATGCATTCGAAAGCTCTTCTAGATAGTTGTTATTGGCT 13
422 mAD GTCTTGTTAATCTGAATGTTATATGCATTCGAAAGCTCTTCTAGATAGTTGTTATTGGCT 13
423 mAD AGGAGTTAATTAGCCAAAGGGAAAACAATCGAAGATTGTTGCTGAGAAAAGTCAATATGA 2
424 sAD AGGAGTTAATTAGCCAAAGGGAAAACAATCGAAGATTGTTGCTGAGAAAAGTCAATATGA 2
425 mAD AAACTTATAACTTCTGCCAATTCTCCCTTCGAATATTTGCAAGGCAGGATTTTGTAATTA 6
426 sAD AAACTTATAACTTCTGCCAATTCTCCCTTCGAATATTTGCAAGGCAGGATTTTGTAATTA 6
427 sAD ACAATATATACTTGAAGAATATTGTCCTTCGAGTATGTCTTTATCAACGGCATGAGAACA 9
428 mAD ACAATATATACTTGAAGAATATTGTCCTTCGAGTATGTCTTTATCAACGGCATGAGAACA 9
429 sAD AATCAAGCTAATTAACACATTCATAACCTCGAATTTCTTTCCAACGAAGGAACTTGTGAA 2
430 mAD AATCAAGCTAATTAACACATTCATAACCTCGAATTTCTTTCCAACGAAGGAACTTGTGAA 2
431 sAD TGAGTGAATATAAATCACTAAAACATGTTCGAACAGGAAACGTCATAGAGAAAACTCAGC 6
432 mAD TGAGTGAATATAAATCACTAAAACATGTTCGAACAGGAAACGTCATAGAGAAAACTCAGC 6
433 sAD CCTTGTACTTACTGCTAGTCTTCTGTTATCGACAATTACTATCAAATGTCTATAACCATT 7
434 mAD CCTTGTACTTACTGCTAGTCTTCTGTTATCGACAATTACTATCAAATGTCTATAACCATT 7
435 sAD TTTTATTGCTTTTTAAAAGAGCTTGTCATCGAAGCTCCTTGTGGACAAGTAGATAATGTG 8
436 mAD TTTTATTGCTTTTTAAAAGAGCTTGTCATCGAAGCTCCTTGTGGACAAGTAGATAATGTG 8
表3.d5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
331 50024584 50024615 50103291 50103322 1 50024584 50028585 50099321 50103322
332 50024584 50024615 50103291 50103322 1 50024584 50028585 50099321 50103322
333 39721868 39721899 39792290 39792321 14 39721868 39725869 39792290 39796291
334 39721868 39721899 39792290 39792321 14 39721868 39725869 39792290 39796291
335 46481483 46481514 46545017 46545048 19 46477513 46481514 46541047 46545048
336 46481483 46481514 46545017 46545048 19 46477513 46481514 46541047 46545048
337 1283617 1283648 1344898 1344929 20 1283617 1287618 1340928 1344929
338 1283617 1283648 1344898 1344929 20 1283617 1287618 1340928 1344929
339 36613363 36613394 36670823 36670854 13 36609393 36613394 36670823 36674824
340 36613363 36613394 36670823 36670854 13 36609393 36613394 36670823 36674824
341 148168867 148168898 148224860 148224891 6 148168867 148172868 148220890 148224891
342 148168867 148168898 148224860 148224891 6 148168867 148172868 148220890 148224891
343 40505666 40505697 40520869 40520900 X 40505666 40509667 40520869 40524870
344 40505666 40505697 40520869 40520900 X 40505666 40509667 40520869 40524870
345 7542352 7542383 7555641 7555672 5 7538382 7542383 7555641 7559642
346 7542352 7542383 7555641 7555672 5 7538382 7542383 7555641 7559642
347 121570719 121570750 121595209 121595240 10 121566749 121570750 121595209 121599210
348 121570719 121570750 121595209 121595240 10 121566749 121570750 121595209 121599210
349 23859209 23859240 23887990 23888021 18 23859209 23863210 23887990 23891991
350 23859209 23859240 23887990 23888021 18 23859209 23863210 23887990 23891991
351 79981700 79981731 80037423 80037454 2 79981700 79985701 80033453 80037454
352 79981700 79981731 80037423 80037454 2 79981700 79985701 80033453 80037454
353 19885722 19885753 19898126 19898157 20 19885722 19889723 19898126 19902127
354 19885722 19885753 19898126 19898157 20 19885722 19889723 19898126 19902127
355 14555692 14555723 14600448 14600479 21 14551722 14555723 14596478 14600479
356 14555692 14555723 14600448 14600479 21 14551722 14555723 14596478 14600479
357 46491022 46491053 46536291 46536322 3 46487052 46491053 46532321 46536322
358 46491022 46491053 46536291 46536322 3 46487052 46491053 46532321 46536322
359 64195292 64195323 64266976 64267007 3 64191322 64195323 64266976 64270977
360 64195292 64195323 64266976 64267007 3 64191322 64195323 64266976 64270977
361 169230654 169230685 169286051 169286082 6 169230654 169234655 169286051 169290052
362 169230654 169230685 169286051 169286082 6 169230654 169234655 169286051 169290052
363 69108055 69108086 69217093 69217124 3 69108055 69112056 69213123 69217124
364 69108055 69108086 69217093 69217124 3 69108055 69112056 69213123 69217124
365 88335985 88336016 88412084 88412115 4 88335985 88339986 88412084 88416085
366 88335985 88336016 88412084 88412115 4 88335985 88339986 88412084 88416085
367 84860156 84860187 84918402 84918433 11 84860156 84864157 84918402 84922403
368 84860156 84860187 84918402 84918433 11 84860156 84864157 84918402 84922403
369 206385274 206385305 206449236 206449267 1 206381304 206385305 206445266 206449267
370 206385274 206385305 206449236 206449267 1 206381304 206385305 206445266 206449267
371 74123975 74124006 74179522 74179553 15 74120005 74124006 74175552 74179553
372 74123975 74124006 74179522 74179553 15 74120005 74124006 74175552 74179553
373 56277586 56277617 56329605 56329636 2 56273616 56277617 56325635 56329636
374 56277586 56277617 56329605 56329636 2 56273616 56277617 56325635 56329636
375 45838996 45839027 45851520 45851551 21 45835026 45839027 45847550 45851551
376 45838996 45839027 45851520 45851551 21 45835026 45839027 45847550 45851551
377 14474187 14474218 14520608 14520639 Y 14470217 14474218 14520608 14524609
378 14474187 14474218 14520608 14520639 Y 14470217 14474218 14520608 14524609
379 21331973 21332004 21374795 21374826 2 21328003 21332004 21374795 21378796
380 21331973 21332004 21374795 21374826 2 21328003 21332004 21374795 21378796
381 70128487 70128518 70190375 70190406 6 70128487 70132488 70186405 70190406
382 70128487 70128518 70190375 70190406 6 70128487 70132488 70186405 70190406
383 37211489 37211520 37233817 37233848 7 37211489 37215490 37229847 37233848
384 37211489 37211520 37233817 37233848 7 37211489 37215490 37229847 37233848
385 74044912 74044943 74079684 74079715 8 74044912 74048913 74075714 74079715
386 74044912 74044943 74079684 74079715 8 74044912 74048913 74075714 74079715
387 104895593 104895624 104915537 104915568 11 104895593 104899594 104915537 104919538
388 104895593 104895624 104915537 104915568 11 104895593 104899594 104915537 104919538
389 117491884 117491915 117513941 117513972 9 117491884 117495885 117513941 117517942
390 117491884 117491915 117513941 117513972 9 117491884 117495885 117513941 117517942
391 177028175 177028206 177116397 177116428 1 177028175 177032176 177116397 177120398
392 177028175 177028206 177116397 177116428 1 177028175 177032176 177116397 177120398
393 177133036 177133067 177178719 177178750 1 177129066 177133067 177178719 177182720
394 177133036 177133067 177178719 177178750 1 177129066 177133067 177178719 177182720
395 76032659 76032690 76083373 76083404 1 76032659 76036660 76083373 76087374
396 76032659 76032690 76083373 76083404 1 76032659 76036660 76083373 76087374
397 76419786 76419817 76444465 76444496 10 76415816 76419817 76444465 76448466
398 76419786 76419817 76444465 76444496 10 76415816 76419817 76444465 76448466
399 59205508 59205539 59259334 59259365 15 59205508 59209509 59259334 59263335
400 59205508 59205539 59259334 59259365 15 59205508 59209509 59259334 59263335
401 35655009 35655040 35676499 35676530 18 35655009 35659010 35676499 35680500
402 35655009 35655040 35676499 35676530 18 35655009 35659010 35676499 35680500
403 106160923 106160954 106222125 106222156 2 106156953 106160954 106218155 106222156
404 106160923 106160954 106222125 106222156 2 106156953 106160954 106218155 106222156
405 20263366 20263397 20369281 20369312 2 20259396 20263397 20365311 20369312
406 20263366 20263397 20369281 20369312 2 20259396 20263397 20365311 20369312
407 217551078 217551109 217605412 217605443 2 217551078 217555079 217605412 217609413
408 217551078 217551109 217605412 217605443 2 217551078 217555079 217605412 217609413
409 11127964 11127995 11191868 11191899 20 11123994 11127995 11191868 11195869
410 11127964 11127995 11191868 11191899 20 11123994 11127995 11191868 11195869
411 125343567 125343598 125382298 125382329 4 125339597 125343598 125382298 125386299
412 125343567 125343598 125382298 125382329 4 125339597 125343598 125382298 125386299
413 5723608 5723639 5745537 5745568 6 5723608 5727609 5745537 5749538
414 5723608 5723639 5745537 5745568 6 5723608 5727609 5745537 5749538
415 45859224 45859255 45923601 45923632 13 45859224 45863225 45923601 45927602
416 45859224 45859255 45923601 45923632 13 45859224 45863225 45923601 45927602
417 74451031 74451062 74472806 74472837 13 74447061 74451062 74472806 74476807
418 74451031 74451062 74472806 74472837 13 74447061 74451062 74472806 74476807
419 66151935 66151966 66218811 66218842 1 66147965 66151966 66218811 66222812
420 66151935 66151966 66218811 66218842 1 66147965 66151966 66218811 66222812
421 74472806 74472837 74514777 74514808 13 74472806 74476807 74510807 74514808
422 74472806 74472837 74514777 74514808 13 74472806 74476807 74510807 74514808
423 19641438 19641469 19664902 19664933 2 19641438 19645439 19660932 19664933
424 19641438 19641469 19664902 19664933 2 19641438 19645439 19660932 19664933
425 27449427 27449458 27518903 27518934 6 27445457 27449458 27514933 27518934
426 27449427 27449458 27518903 27518934 6 27445457 27449458 27514933 27518934
427 105415770 105415801 105443172 105443203 9 105411800 105415801 105439202 105443203
428 105415770 105415801 105443172 105443203 9 105411800 105415801 105439202 105443203
429 161568697 161568728 161587453 161587484 2 161568697 161572698 161583483 161587484
430 161568697 161568728 161587453 161587484 2 161568697 161572698 161583483 161587484
431 84687731 84687762 84786605 84786636 6 84687731 84691732 84782635 84786636
432 84687731 84687762 84786605 84786636 6 84687731 84691732 84782635 84786636
433 107254515 107254546 107284754 107284785 7 107250545 107254546 107284754 107288755
434 107254515 107254546 107284754 107284785 7 107250545 107254546 107284754 107288755
435 119154139 119154170 119209458 119209489 8 119154139 119158140 119209458 119213459
436 119154139 119154170 119209458 119209489 8 119154139 119158140 119209458 119213459
表3.d6
   探針 PCR- 引子 1_ID PCR_ 引子 1
331 ORF175_1_50024584_50030848_50095924_50103322_RF OBD159_2021 GGCGATTTAGACAGGTTAGACATCCA
332 ORF175_1_50024584_50030848_50095924_50103322_RF OBD159_2021 GGCGATTTAGACAGGTTAGACATCCA
333 ORF176_14_39721868_39724679_39792290_39806170_RR OBD159_2025 TTATGAATGCTAACAAAGTGCTGT
334 ORF176_14_39721868_39724679_39792290_39806170_RR OBD159_2025 TTATGAATGCTAACAAAGTGCTGT
335 ORF176_19_46479838_46481514_46541191_46545048_FF OBD159_1973 GGTCTGAACACAGTCTTGGCTGG
336 ORF176_19_46479838_46481514_46541191_46545048_FF OBD159_1973 GGTCTGAACACAGTCTTGGCTGG
337 ORF176_20_1283617_1286683_1342450_1344929_RF OBD159_2029 CTTTTAGAAGAGAAATAGGAGATT
338 ORF176_20_1283617_1286683_1342450_1344929_RF OBD159_2029 CTTTTAGAAGAGAAATAGGAGATT
339 ORF177_13_36604370_36613394_36670823_36673255_FR OBD159_2033 TCTCTTTCCAGACACTGCTCGGCACT
340 ORF177_13_36604370_36613394_36670823_36673255_FR OBD159_2033 TCTCTTTCCAGACACTGCTCGGCACT
341 ORF177_6_148168867_148173481_148222776_148224891_RF OBD159_2037 GAATGAGTAATGAGATGGGAGATGGG
342 ORF177_6_148168867_148173481_148222776_148224891_RF OBD159_2037 GAATGAGTAATGAGATGGGAGATGGG
343 ORF177_X_40505666_40507827_40520869_40522158_RR OBD159_2041 CAAACTACTCTAATCCCAGGTGGCTA
344 ORF177_X_40505666_40507827_40520869_40522158_RR OBD159_2041 CAAACTACTCTAATCCCAGGTGGCTA
345 ORF179_5_7540900_7542383_7555641_7557907_FR OBD159_2045 AATCTGAACTTAGACAGGCTGGCTGC
346 ORF179_5_7540900_7542383_7555641_7557907_FR OBD159_2045 AATCTGAACTTAGACAGGCTGGCTGC
347 ORF18_10_121564423_121570750_121595209_121596934_FR OBD159_2049 CTCATCTCCTGCCAAAACGCAATGGG
348 ORF18_10_121564423_121570750_121595209_121596934_FR OBD159_2049 CTCATCTCCTGCCAAAACGCAATGGG
349 ORF18_18_23859209_23862260_23887990_23889494_RR OBD159_2053 CCTCCAGGTAGAGAGTGTCAGAAGTG
350 ORF18_18_23859209_23862260_23887990_23889494_RR OBD159_2053 CCTCCAGGTAGAGAGTGTCAGAAGTG
351 ORF18_2_79981700_79985274_80035781_80037454_RF OBD159_2057 TCCTCTGTTCTCAACTCGGTCTCAGT
352 ORF18_2_79981700_79985274_80035781_80037454_RF OBD159_2057 TCCTCTGTTCTCAACTCGGTCTCAGT
353 ORF18_20_19885722_19887043_19898126_19900554_RR OBD159_2061 TCCGCTCCTCTCCTCTTCTCTTA
354 ORF18_20_19885722_19887043_19898126_19900554_RR OBD159_2061 TCCGCTCCTCTCCTCTTCTCTTA
355 ORF18_21_14553845_14555723_14583254_14600479_FF OBD159_2065 GCCTTTCCATTGAAGCCCATTCTTAC
356 ORF18_21_14553845_14555723_14583254_14600479_FF OBD159_2065 GCCTTTCCATTGAAGCCCATTCTTAC
357 ORF18_3_46488317_46491053_46529967_46536322_FF OBD159_2069 AGGAGGCTGTGTAGACCAAAACCACG
358 ORF18_3_46488317_46491053_46529967_46536322_FF OBD159_2069 AGGAGGCTGTGTAGACCAAAACCACG
359 ORF18_3_64194265_64195323_64266976_64268244_FR OBD159_2073 GCCTTTCCTTTCTGGCATCATCTGTT
360 ORF18_3_64194265_64195323_64266976_64268244_FR OBD159_2073 GCCTTTCCTTTCTGGCATCATCTGTT
361 ORF18_6_169230654_169232256_169286051_169290790_RR OBD159_2077 TATGTTACACCCCTTGGCTACCCAGC
362 ORF18_6_169230654_169232256_169286051_169290790_RR OBD159_2077 TATGTTACACCCCTTGGCTACCCAGC
363 ORF180_3_69108055_69110182_69214794_69217124_RF OBD159_2081 CTTGGAGTTTCTTCAAATAAAATC
364 ORF180_3_69108055_69110182_69214794_69217124_RF OBD159_2081 CTTGGAGTTTCTTCAAATAAAATC
365 ORF180_4_88335985_88339586_88412084_88413091_RR OBD159_2085 TGGAGAGAAAGACATCAATCACAT
366 ORF180_4_88335985_88339586_88412084_88413091_RR OBD159_2085 TGGAGAGAAAGACATCAATCACAT
367 ORF181_11_84860156_84861867_84918402_84924862_RR OBD159_2089 GGTTGAGGAGGCGTATCATTTAGCAC
368 ORF181_11_84860156_84861867_84918402_84924862_RR OBD159_2089 GGTTGAGGAGGCGTATCATTTAGCAC
369 ORF182_1_206383244_206385305_206447306_206449267_FF OBD159_2093 CTCTGAAGCCAAGCATAGATAGATGG
370 ORF182_1_206383244_206385305_206447306_206449267_FF OBD159_2093 CTCTGAAGCCAAGCATAGATAGATGG
371 ORF183_15_74122056_74124006_74177775_74179553_FF OBD159_2097 GCTGGGTGCGATGTGTGCCTCTA
372 ORF183_15_74122056_74124006_74177775_74179553_FF OBD159_2097 GCTGGGTGCGATGTGTGCCTCTA
373 ORF183_2_56270885_56277617_56323476_56329636_FF OBD159_2101 CCCTAACTTTGACTTGCTATGTGATA
374 ORF183_2_56270885_56277617_56323476_56329636_FF OBD159_2101 CCCTAACTTTGACTTGCTATGTGATA
375 ORF183_21_45837532_45839027_45849840_45851551_FF OBD159_2105 CCCTTCCTTCTCCTGTAAGTAGC
376 ORF183_21_45837532_45839027_45849840_45851551_FF OBD159_2105 CCCTTCCTTCTCCTGTAAGTAGC
377 ORF184_Y_14466176_14474218_14520608_14523189_FR OBD159_2109 GGGACATTAGTTTACCCAGTATGGAC
378 ORF184_Y_14466176_14474218_14520608_14523189_FR OBD159_2109 GGGACATTAGTTTACCCAGTATGGAC
379 ORF187_2_21325579_21332004_21374795_21382106_FR OBD159_2113 GGAGAGAGACTGAAGGCAGGAATGCT
380 ORF187_2_21325579_21332004_21374795_21382106_FR OBD159_2113 GGAGAGAGACTGAAGGCAGGAATGCT
381 ORF187_6_70128487_70130693_70187099_70190406_RF OBD159_2117 GAAGTTTCAAATAGGCAAGCCAACCC
382 ORF187_6_70128487_70130693_70187099_70190406_RF OBD159_2117 GAAGTTTCAAATAGGCAAGCCAACCC
383 ORF187_7_37211489_37214787_37231292_37233848_RF OBD159_2121 GCTTAGGCAGGGCAATGTGCTTCC
384 ORF187_7_37211489_37214787_37231292_37233848_RF OBD159_2121 GCTTAGGCAGGGCAATGTGCTTCC
385 ORF187_8_74044912_74046076_74077219_74079715_RF OBD159_2125 AGATGGCTGTGGTGTTCGCTTTGGCA
386 ORF187_8_74044912_74046076_74077219_74079715_RF OBD159_2125 AGATGGCTGTGGTGTTCGCTTTGGCA
387 ORF188_11_104895593_104903291_104915537_104922612_RR OBD159_2129 CACAGCCAATCTGACTGGAGAGTAGG
388 ORF188_11_104895593_104903291_104915537_104922612_RR OBD159_2129 CACAGCCAATCTGACTGGAGAGTAGG
389 ORF188_9_117491884_117500665_117513941_117521837_RR OBD159_2133 GTCCTGGTCCCTAAGGCTTCACTTGA
390 ORF188_9_117491884_117500665_117513941_117521837_RR OBD159_2133 GTCCTGGTCCCTAAGGCTTCACTTGA
391 ORF19_1_177028175_177032504_177116397_177122010_RR OBD159_2137 GGGTCTCCCAATCTCCCTTGATACTT
392 ORF19_1_177028175_177032504_177116397_177122010_RR OBD159_2137 GGGTCTCCCAATCTCCCTTGATACTT
393 ORF19_1_177129764_177133067_177178719_177181987_FR OBD159_2141 ATTGGTGGTTTCCCTCTCCTTGTGAT
394 ORF19_1_177129764_177133067_177178719_177181987_FR OBD159_2141 ATTGGTGGTTTCCCTCTCCTTGTGAT
395 ORF19_1_76032659_76035831_76083373_76086337_RR OBD159_2145 CGCCAGGGAGGGCATAATCTCTG
396 ORF19_1_76032659_76035831_76083373_76086337_RR OBD159_2145 CGCCAGGGAGGGCATAATCTCTG
397 ORF19_10_76413183_76419817_76444465_76451876_FR OBD159_2149 CCACCAGCAGTTATTGAGCATTCCTT
398 ORF19_10_76413183_76419817_76444465_76451876_FR OBD159_2149 CCACCAGCAGTTATTGAGCATTCCTT
399 ORF19_15_59205508_59210997_59259334_59261999_RR OBD159_2153 GCCATCCAGGCAGCCAGATACTC
400 ORF19_15_59205508_59210997_59259334_59261999_RR OBD159_2153 GCCATCCAGGCAGCCAGATACTC
401 ORF19_18_35655009_35656946_35676499_35681362_RR OBD159_2157 CCCCTTAGGAATGAGATGGGAGG
402 ORF19_18_35655009_35656946_35676499_35681362_RR OBD159_2157 CCCCTTAGGAATGAGATGGGAGG
403 ORF19_2_106158642_106160954_106220910_106222156_FF OBD159_2161 AGCAGCCAAGTTTTAGATTTCATA
404 ORF19_2_106158642_106160954_106220910_106222156_FF OBD159_2161 AGCAGCCAAGTTTTAGATTTCATA
405 ORF19_2_20261188_20263397_20361646_20369312_FF OBD159_2165 GAAATCTTCCAATAATCTACTGCGGC
406 ORF19_2_20261188_20263397_20361646_20369312_FF OBD159_2165 GAAATCTTCCAATAATCTACTGCGGC
407 ORF19_2_217551078_217557187_217605412_217608263_RR OBD159_2169 CTTCTGAGCCTTATGAAAACGGGCAT
408 ORF19_2_217551078_217557187_217605412_217608263_RR OBD159_2169 CTTCTGAGCCTTATGAAAACGGGCAT
409 ORF19_20_11126224_11127995_11191868_11199236_FR OBD159_2173 CCCAACTCTCTCCTTTGACACAACAG
410 ORF19_20_11126224_11127995_11191868_11199236_FR OBD159_2173 CCCAACTCTCTCCTTTGACACAACAG
411 ORF19_4_125340607_125343598_125382298_125392915_FR OBD159_2177 TCCTCCCACTTCACCTCCTGTGC
412 ORF19_4_125340607_125343598_125382298_125392915_FR OBD159_2177 TCCTCCCACTTCACCTCCTGTGC
413 ORF19_6_5723608_5725733_5745537_5748323_RR OBD159_2181 CAACAACCTTTTCCTCACACGCA
414 ORF19_6_5723608_5725733_5745537_5748323_RR OBD159_2181 CAACAACCTTTTCCTCACACGCA
415 ORF191_13_45859224_45860475_45923601_45927773_RR OBD159_2185 GCCCTCTTCCTTTCCCTCCTGTA
416 ORF191_13_45859224_45860475_45923601_45927773_RR OBD159_2185 GCCCTCTTCCTTTCCCTCCTGTA
417 ORF191_13_74443077_74451062_74472806_74486278_FR OBD159_2189 TCCCTTTGCTAAACTTGCCTCTGCCC
418 ORF191_13_74443077_74451062_74472806_74486278_FR OBD159_2189 TCCCTTTGCTAAACTTGCCTCTGCCC
419 ORF193_1_66143825_66151966_66218811_66223865_FR OBD159_2193 ATCCAGAATGAGGCTCTCCCCAGCAT
420 ORF193_1_66143825_66151966_66218811_66223865_FR OBD159_2193 ATCCAGAATGAGGCTCTCCCCAGCAT
421 ORF194_13_74472806_74486278_74508577_74514808_RF OBD159_2197 GACAAATCTTCTGTTCCACAAGTTAG
422 ORF194_13_74472806_74486278_74508577_74514808_RF OBD159_2197 GACAAATCTTCTGTTCCACAAGTTAG
423 ORF194_2_19641438_19647635_19660555_19664933_RF OBD159_2201 CTACTTGGAGAACAAAAGCCACCAGC
424 ORF194_2_19641438_19647635_19660555_19664933_RF OBD159_2201 CTACTTGGAGAACAAAAGCCACCAGC
425 ORF194_6_27448356_27449458_27517801_27518934_FF OBD159_2205 GCTGGCTTTACTGATAACTTCCGAGG
426 ORF194_6_27448356_27449458_27517801_27518934_FF OBD159_2205 GCTGGCTTTACTGATAACTTCCGAGG
427 ORF194_9_105414393_105415801_105438651_105443203_FF OBD159_2209 GCGACACCTGCTGGTTGAGAGTG
428 ORF194_9_105414393_105415801_105438651_105443203_FF OBD159_2209 GCGACACCTGCTGGTTGAGAGTG
429 ORF195_2_161568697_161570567_161580634_161587484_RF OBD159_2213 TGGTTATTTTGGAGAGGAAAGAAA
430 ORF195_2_161568697_161570567_161580634_161587484_RF OBD159_2213 TGGTTATTTTGGAGAGGAAAGAAA
431 ORF196_6_84687731_84692812_84775145_84786636_RF OBD159_2217 GATGACTGTTTTCAGAGACAATGGAA
432 ORF196_6_84687731_84692812_84775145_84786636_RF OBD159_2217 GATGACTGTTTTCAGAGACAATGGAA
433 ORF197_7_107251976_107254546_107284754_107287455_FR OBD159_2221 GCAATGAAGTCTCTAACTGATGAGGC
434 ORF197_7_107251976_107254546_107284754_107287455_FR OBD159_2221 GCAATGAAGTCTCTAACTGATGAGGC
435 ORF198_8_119154139_119162140_119209458_119214583_RR OBD159_2225 TTCAGAAATCAAAGCCCAAAATGC
436 ORF198_8_119154139_119162140_119209458_119214583_RR OBD159_2225 TTCAGAAATCAAAGCCCAAAATGC
表3.d7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
331 OBD159_2023 CTTCCCTCTTTCACTCTCTCCACCTC OBD159_2021_2023 0.002383764
332 OBD159_2023 CTTCCCTCTTTCACTCTCTCCACCTC OBD159_2021_2023 0.002383764
333 OBD159_2027 TCTCCAGTTGTTAGTGTTTCAATA OBD159_2025_2027 0.000706158
334 OBD159_2027 TCTCCAGTTGTTAGTGTTTCAATA OBD159_2025_2027 0.000706158
335 OBD159_1975 CTCACGCCTGGGAGAGTTTGTGC OBD159_1973_1975 0.001414727
336 OBD159_1975 CTCACGCCTGGGAGAGTTTGTGC OBD159_1973_1975 0.001414727
337 OBD159_2031 ACTACGGAGATTCCAAACTGGCAG OBD159_2029_2031 0.002008835
338 OBD159_2031 ACTACGGAGATTCCAAACTGGCAG OBD159_2029_2031 0.002008835
339 OBD159_2035 TACCCGACTTGCCAGTATCACTAC OBD159_2033_2035 0.001678606
340 OBD159_2035 TACCCGACTTGCCAGTATCACTAC OBD159_2033_2035 0.001678606
341 OBD159_2039 CCCTGTTCCTCCCACTTCCTCTTAGA OBD159_2037_2039 0.00171494
342 OBD159_2039 CCCTGTTCCTCCCACTTCCTCTTAGA OBD159_2037_2039 0.00171494
343 OBD159_2043 GACACCTACCAACCCAGATGCTCTTG OBD159_2041_2043 0.000850351
344 OBD159_2043 GACACCTACCAACCCAGATGCTCTTG OBD159_2041_2043 0.000850351
345 OBD159_2047 GGAGCCTAAAGTTATGGGAATGTCAT OBD159_2045_2047 0.001542025
346 OBD159_2047 GGAGCCTAAAGTTATGGGAATGTCAT OBD159_2045_2047 0.001542025
347 OBD159_2051 CACCGTTTCACCTGTGCTATCTTTGA OBD159_2049_2051 0.001207274
348 OBD159_2051 CACCGTTTCACCTGTGCTATCTTTGA OBD159_2049_2051 0.001207274
349 OBD159_2055 GGCTTTACTTTGTGACTGGCTTGGTA OBD159_2053_2055 0.001843195
350 OBD159_2055 GGCTTTACTTTGTGACTGGCTTGGTA OBD159_2053_2055 0.001843195
351 OBD159_2059 TGGGCAAGTTTGACTGGACATTTTCT OBD159_2057_2059 0.000753371
352 OBD159_2059 TGGGCAAGTTTGACTGGACATTTTCT OBD159_2057_2059 0.000753371
353 OBD159_2063 GCTGTTAGCATCAGAAATGAATGGC OBD159_2061_2063 0.001707301
354 OBD159_2063 GCTGTTAGCATCAGAAATGAATGGC OBD159_2061_2063 0.001707301
355 OBD159_2067 CCAGTGCCTACTCCCAAACGACGATT OBD159_2065_2067 0.001673011
356 OBD159_2067 CCAGTGCCTACTCCCAAACGACGATT OBD159_2065_2067 0.001673011
357 OBD159_2071 AGTGTGAATACCCAGGAAACTTAGCG OBD159_2069_2071 0.002527
358 OBD159_2071 AGTGTGAATACCCAGGAAACTTAGCG OBD159_2069_2071 0.002527
359 OBD159_2075 GGAAAGATTGTGGGTAGGTGCTGGGT OBD159_2073_2075 0.001051096
360 OBD159_2075 GGAAAGATTGTGGGTAGGTGCTGGGT OBD159_2073_2075 0.001051096
361 OBD159_2079 CTTAGTCATAAATCCTTTGGCAGACC OBD159_2077_2079 0.00039807
362 OBD159_2079 CTTAGTCATAAATCCTTTGGCAGACC OBD159_2077_2079 0.00039807
363 OBD159_2083 CTTGAACTACTTATCCTATTCTTTA OBD159_2081_2083 0.000209607
364 OBD159_2083 CTTGAACTACTTATCCTATTCTTTA OBD159_2081_2083 0.000209607
365 OBD159_2087 AGTGGGAATAAACTTGTATGGTAT OBD159_2085_2087 0.001646676
366 OBD159_2087 AGTGGGAATAAACTTGTATGGTAT OBD159_2085_2087 0.001646676
367 OBD159_2091 TCCTGTGATGGGAATCCTTTCTCTGC OBD159_2089_2091 -0.000136903
368 OBD159_2091 TCCTGTGATGGGAATCCTTTCTCTGC OBD159_2089_2091 -0.000136903
369 OBD159_2095 GTAAGAACTTCCTGGTGCCCATCCTC OBD159_2093_2095 0.000702852
370 OBD159_2095 GTAAGAACTTCCTGGTGCCCATCCTC OBD159_2093_2095 0.000702852
371 OBD159_2099 AGTGTTCCTGACAGTGTAGGCGG OBD159_2097_2099 0.000137282
372 OBD159_2099 AGTGTTCCTGACAGTGTAGGCGG OBD159_2097_2099 0.000137282
373 OBD159_2103 CTGGAGAGGAGGAGTCTTGTTTGCTT OBD159_2101_2103 0.000847279
374 OBD159_2103 CTGGAGAGGAGGAGTCTTGTTTGCTT OBD159_2101_2103 0.000847279
375 OBD159_2107 TAGTGAGCCAAGATTGTGCCCTT OBD159_2105_2107 0.002510944
376 OBD159_2107 TAGTGAGCCAAGATTGTGCCCTT OBD159_2105_2107 0.002510944
377 OBD159_2111 CTGACACAGTCCTAAGCACAGACAT OBD159_2109_2111 0.001454009
378 OBD159_2111 CTGACACAGTCCTAAGCACAGACAT OBD159_2109_2111 0.001454009
379 OBD159_2115 GGTGAGAGTGACTTGGTGACTTTGAA OBD159_2113_2115 0.000271609
380 OBD159_2115 GGTGAGAGTGACTTGGTGACTTTGAA OBD159_2113_2115 0.000271609
381 OBD159_2119 GACACCACTTATGTAACTCCTGTTTA OBD159_2117_2119 0.00079638
382 OBD159_2119 GACACCACTTATGTAACTCCTGTTTA OBD159_2117_2119 0.00079638
383 OBD159_2123 GACCCCAGGGAAAGAGGGAGTAT OBD159_2121_2123 0.002143031
384 OBD159_2123 GACCCCAGGGAAAGAGGGAGTAT OBD159_2121_2123 0.002143031
385 OBD159_2127 AGGGAGCAAAGATTATCAGACAGTGC OBD159_2125_2127 0.000591997
386 OBD159_2127 AGGGAGCAAAGATTATCAGACAGTGC OBD159_2125_2127 0.000591997
387 OBD159_2131 CTTCCTACATTCGCTTGACTGGTGAT OBD159_2129_2131 0.000713807
388 OBD159_2131 CTTCCTACATTCGCTTGACTGGTGAT OBD159_2129_2131 0.000713807
389 OBD159_2135 GGACCACATACTTACATTTGGACCAC OBD159_2133_2135 0.002701307
390 OBD159_2135 GGACCACATACTTACATTTGGACCAC OBD159_2133_2135 0.002701307
391 OBD159_2139 CAATGAAGGAAAAGAGAGGGAGGAGG OBD159_2137_2139 0.001441658
392 OBD159_2139 CAATGAAGGAAAAGAGAGGGAGGAGG OBD159_2137_2139 0.001441658
393 OBD159_2143 GAATGGAAGCAACTTGAGGGCAGACC OBD159_2141_2143 0.001668614
394 OBD159_2143 GAATGGAAGCAACTTGAGGGCAGACC OBD159_2141_2143 0.001668614
395 OBD159_2147 CAAAGCCAGGATGGGACTCAGAG OBD159_2145_2147 0.001918512
396 OBD159_2147 CAAAGCCAGGATGGGACTCAGAG OBD159_2145_2147 0.001918512
397 OBD159_2151 AGGCTGTGCTTGGCTGGTTGTGTAAC OBD159_2149_2151 0.001018689
398 OBD159_2151 AGGCTGTGCTTGGCTGGTTGTGTAAC OBD159_2149_2151 0.001018689
399 OBD159_2155 CCCCTAACAGACCAGACCAAACC OBD159_2153_2155 0.000307015
400 OBD159_2155 CCCCTAACAGACCAGACCAAACC OBD159_2153_2155 0.000307015
401 OBD159_2159 CGCCTGTCAGTGGGAGTGGGAAA OBD159_2157_2159 0.001008103
402 OBD159_2159 CGCCTGTCAGTGGGAGTGGGAAA OBD159_2157_2159 0.001008103
403 OBD159_2163 CCAAAGTTCTGGGATTACAGGCAT OBD159_2161_2163 0.000518272
404 OBD159_2163 CCAAAGTTCTGGGATTACAGGCAT OBD159_2161_2163 0.000518272
405 OBD159_2167 CAGTCTCTTTCTCTCTGGAATCC OBD159_2165_2167 0.000674888
406 OBD159_2167 CAGTCTCTTTCTCTCTGGAATCC OBD159_2165_2167 0.000674888
407 OBD159_2171 GTCCTGAACTCATCCCGTCTTCTCCA OBD159_2169_2171 0.000823884
408 OBD159_2171 GTCCTGAACTCATCCCGTCTTCTCCA OBD159_2169_2171 0.000823884
409 OBD159_2175 TTGTCCACATCTTCCCCATCTGAGAA OBD159_2173_2175 0.001538354
410 OBD159_2175 TTGTCCACATCTTCCCCATCTGAGAA OBD159_2173_2175 0.001538354
411 OBD159_2179 TACATTCCTGGTAACACAGCATCCAT OBD159_2177_2179 0.000652174
412 OBD159_2179 TACATTCCTGGTAACACAGCATCCAT OBD159_2177_2179 0.000652174
413 OBD159_2183 AGCCTGGGTGACAGAGTGAGACC OBD159_2181_2183 0.001983308
414 OBD159_2183 AGCCTGGGTGACAGAGTGAGACC OBD159_2181_2183 0.001983308
415 OBD159_2187 ATGGAGGTGGTGGGCAATGGCAC OBD159_2185_2187 0.002273727
416 OBD159_2187 ATGGAGGTGGTGGGCAATGGCAC OBD159_2185_2187 0.002273727
417 OBD159_2191 GGGAGAGGATAGGTTTAGTTGCCT OBD159_2189_2191 0
418 OBD159_2191 GGGAGAGGATAGGTTTAGTTGCCT OBD159_2189_2191 0
419 OBD159_2195 GAGAAGACAGGAACACTGATGCTATC OBD159_2193_2195 0.001003098
420 OBD159_2195 GAGAAGACAGGAACACTGATGCTATC OBD159_2193_2195 0.001003098
421 OBD159_2199 GGGAGAGGATAGGTTTAGTTGCCT OBD159_2197_2199 0.002044234
422 OBD159_2199 GGGAGAGGATAGGTTTAGTTGCCT OBD159_2197_2199 0.002044234
423 OBD159_2203 TGTGCCCTGGAGAAACAGTCTATCTG OBD159_2201_2203 0.002653152
424 OBD159_2203 TGTGCCCTGGAGAAACAGTCTATCTG OBD159_2201_2203 0.002653152
425 OBD159_2207 CTCCTTCCTCAGCCTTTCTGTTTGAC OBD159_2205_2207 0.002407868
426 OBD159_2207 CTCCTTCCTCAGCCTTTCTGTTTGAC OBD159_2205_2207 0.002407868
427 OBD159_2211 CCCACATCAGGGCAGAACCATTC OBD159_2209_2211 0.001662726
428 OBD159_2211 CCCACATCAGGGCAGAACCATTC OBD159_2209_2211 0.001662726
429 OBD159_2215 AGGAAAGCCTCAGTGTTAGAATGC OBD159_2213_2215 0.000402127
430 OBD159_2215 AGGAAAGCCTCAGTGTTAGAATGC OBD159_2213_2215 0.000402127
431 OBD159_2219 TAAGCAAAGCCCTTCTTCCCCTGTCT OBD159_2217_2219 0
432 OBD159_2219 TAAGCAAAGCCCTTCTTCCCCTGTCT OBD159_2217_2219 0
433 OBD159_2223 GCTGGTGGAAGGATTGTAAACAGGGA OBD159_2221_2223 0.000829972
434 OBD159_2223 GCTGGTGGAAGGATTGTAAACAGGGA OBD159_2221_2223 0.000829972
435 OBD159_2227 CTAACTCGCTAACATTTCACTTTT OBD159_2225_2227 0.001079616
436 OBD159_2227 CTAACTCGCTAACATTTCACTTTT OBD159_2225_2227 0.001079616
表3.d8
   基因
331 AGBL4; ELAVL4; rs11583200
332 AGBL4; ELAVL4; rs11583200
333 rs17109786; rs148431766
334 rs17109786; rs148431766
335 PNMAL1; PNMAL2; PPP5D1
336 PNMAL1; PNMAL2; PPP5D1
337 FKBP1A; RAD21L1; RP11-314N13.10; SDCBP2; SNPH; rs35367003
338 FKBP1A; RAD21L1; RP11-314N13.10; SDCBP2; SNPH; rs35367003
339 SERTM1; rs11619726
340 SERTM1; rs11619726
341 rs6914622; rs9497965; rs9497975
342 rs6914622; rs9497965; rs9497975
343 BCOR; rs2968915
344 BCOR; rs2968915
345 ADCY2; rs17231202; rs10512928; rs884964; rs12522444; rs11134242
346 ADCY2; rs17231202; rs10512928; rs884964; rs12522444; rs11134242
347 FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs755001161
348 FGFR2; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718; rs755001161
349 LAMA3; rs1057516512; rs80356678; rs1057516743; rs1057517023; rs1057516475; rs1057517235; rs1057517367; rs7237244
350 LAMA3; rs1057516512; rs80356678; rs1057516743; rs1057517023; rs1057516475; rs1057517235; rs1057517367; rs7237244
351 CTNNA2; rs6738962
352 CTNNA2; rs6738962
353 RIN2; rs6046396
354 RIN2; rs6046396
355 AF165138.7; HSPA13; SAMSN1
356 AF165138.7; HSPA13; SAMSN1
357 LRRC2; LTF; RTP3
358 LRRC2; LTF; RTP3
359 PRICKLE2; rs17404667
360 PRICKLE2; rs17404667
361 THBS2; rs9406328; rs761646500; rs116146467
362 THBS2; rs9406328; rs761646500; rs116146467
363 ARL6IP5; FRMD4B; LMOD3; rs724159964; rs727502798; rs727502799; rs724159965; rs727502797; rs6787362; rs6806528
364 ARL6IP5; FRMD4B; LMOD3; rs724159964; rs727502798; rs727502799; rs724159965; rs727502797; rs6787362; rs6806528
365 HERC6; rs12512051
366 HERC6; rs12512051
367 DLG2
368 DLG2
369 SRGAP2; rs2987927; rs2480408
370 SRGAP2; rs2987927; rs2480408
371 ISLR; ISLR2; STRA6; rs376998994; rs397514639
372 ISLR; ISLR2; STRA6; rs376998994; rs397514639
373 CCDC85A; rs6747380
374 CCDC85A; rs6747380
375 PCBP3; rs56127133
376 PCBP3; rs56127133
377 NLGN4Y
378 NLGN4Y
379 rs2337901; rs11897825
380 rs2337901; rs11897825
381 COL19A1; rs771562232; rs658805
382 COL19A1; rs771562232; rs658805
383 ELMO1; rs73112661
384 ELMO1; rs73112661
385 LY96; rs6472827
386 LY96; rs6472827
387 CASP4; rs497116
388 CASP4; rs497116
389 ASTN2; rs2771051
390 ASTN2; rs2771051
391 ASTN1; rs2861887; rs228014
392 ASTN1; rs2861887; rs228014
393 ASTN1; BRINP2; rs2861887
394 ASTN1; BRINP2; rs2861887
395 ST6GALNAC3; rs12095069
396 ST6GALNAC3; rs12095069
397 C10orf11; rs11593840; rs10509373
398 C10orf11; rs11593840; rs10509373
399 LDHAL6B; MYO1E; rs7165001; rs387906807; rs2306786
400 LDHAL6B; MYO1E; rs7165001; rs387906807; rs2306786
401 GALNT1; rs17647532
402 GALNT1; rs17647532
403 C2orf40; UXS1; rs6738485
404 C2orf40; UXS1; rs6738485
405 PUM2; rs111612372
406 PUM2; rs111612372
407 DIRC3; rs6435999
408 DIRC3; rs6435999
409 rs6040399; rs77790871
410 rs6040399; rs77790871
411 FAT4; rs1039808
412 FAT4; rs1039808
413 FARS2; rs775690041
414 FARS2; rs775690041
415 SIAH3; ZC3H13
416 SIAH3; ZC3H13
417 rs17714988; rs17718828
418 rs17714988; rs17718828
419 PDE4B; rs490094; rs10454453; rs486438; rs567279; rs6588190
420 PDE4B; rs490094; rs10454453; rs486438; rs567279; rs6588190
421 rs17714988; rs17718828
422 rs17714988; rs17718828
423 rs10856789; rs16986953
424 rs10856789; rs16986953
425 ZNF184; rs34196306; rs149866169; rs34864796; rs16867808; rs2205829; rs13195040
426 ZNF184; rs34196306; rs149866169; rs34864796; rs16867808; rs2205829; rs13195040
427 FSD1L; SLC44A1
428 FSD1L; SLC44A1
429 SLC4A10; rs56037433
430 SLC4A10; rs56037433
431 TBX18; rs760905589; rs869320679; rs797045022; rs77693245; rs72912698
432 TBX18; rs760905589; rs869320679; rs797045022; rs77693245; rs72912698
433 COG5; rs773281248; rs3815148
434 COG5; rs773281248; rs3815148
435 MAL2; rs2468186; rs1425053; rs6989684
436 MAL2; rs2468186; rs1425053; rs6989684
表3.d9
   探針 基因座
1 ORF1_1_58851578_58854234_58918114_58921170_FR rs2760501; rs6668586
2 ORF1_10_114879815_114883799_114930122_114938828_RR FAM160B1; TRUB1; rs968847
3 ORF1_12_109687914_109689169_109761674_109764027_RR FAM222A; rs763757845
4 ORF1_14_64426803_64429125_64462354_64463999_RR MTHFD1; ZBTB25; rs34181110; rs2236225; rs2281603
5 ORF1_16_23216838_23220910_23281989_23283335_RF SCNN1B; SCNN1G; rs137853342
6 ORF1_2_26839991_26843135_26900262_26907333_FR DPYSL5; rs1371614
7 ORF1_21_17391129_17392895_17434190_17435748_FF CXADR
8 ORF1_21_17391129_17392895_17437778_17439433_FF CXADR
9 ORF1_21_17393292_17394472_17441050_17442330_RR CXADR
10 ORF1_5_56137297_56140860_56168655_56170386_FR ANKRD55; rs159572; rs6859219; rs10065637; rs71624119; rs10213692; rs7731626; rs28722705
11 ORF1_5_56137297_56140860_56180306_56182093_FF ANKRD55; rs159572; rs6859219; rs10065637; rs71624119; rs10213692; rs7731626; rs28722705
12 ORF1_5_56137297_56140860_56230314_56232440_FF ANKRD55; rs1020388; rs6859219; rs10065637; rs71624119; rs10213692; rs7731626; rs28722705; rs159572; rs4700060
13 ORF1_8_28429398_28430402_28471461_28475878_FR FBXO16; FZD3
14 ORF10_1_110141802_110145853_110155952_110164041_RF SLC6A17; rs775085213
15 ORF10_1_110155952_110164041_110258457_110260696_FF KCNC4; SLC6A17; UBL4B; rs775085213; rs375380880
16 ORF10_10_121564423_121570750_121595209_121596934_FF FGFR2; rs755001161; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718
17 ORF10_10_127007_130384_175918_183761_RF ZMYND11; rs606231267; rs1060499626; rs1135401797
18 ORF10_11_98953280_98957080_99019353_99022313_FF CNTN5; rs1394461
19 ORF10_15_91096267_91099737_91157513_91165785_RF SV2B; rs886144
20 ORF10_16_27283060_27288284_27358113_27360574_FR IL4R; rs769790595; rs2107356; rs3785356; rs1805010; rs764099093; rs370524692; rs3024647
21 ORF10_3_107626100_107637571_107703592_107708851_RR BBX; rs670752
22 ORF10_3_120814252_120821896_120858831_120873172_FR GTF2E1; rs322458
23 ORF10_4_37845589_37847420_37862832_37864637_RR GAFA3; PGM2
24 ORF10_X_130763205_130766490_130793708_130805512_FR ARHGAP36; ENOX2
25 ORF10_X_68908108_68921078_68942609_68947661_FF EFNB1; rs5937157
26 ORF100_12_54589309_54591607_54654414_54660876_FR DCD; LACRT; PPP1R1A
27 ORF101_14_64426803_64429125_64462354_64463999_RR MTHFD1; ZBTB25; rs34181110; rs2236225; rs2281603
28 ORF104_6_151443530_151449164_151559030_151566602_FF C6orf211; CCDC170; RMND1; rs9479072; rs6933660; rs1971256; rs9479055; rs6931664; rs9479068; rs7761420; rs9478217; rs7753676
29 ORF105_3_85660887_85666710_85682353_85685845_RR CADM2; rs9829032
30 ORF106_15_97695238_97699387_97751925_97755483_FR ARRDC4
31 ORF106_16_15155840_15159398_15200610_15205140_FR PDXDC1; rs4003228
32 ORF107_9_89728565_89736522_89805232_89809003_RR rs12554199
33 ORF109_6_82035912_82039349_82086732_82090252_RR IBTK; rs10806235
34 ORF109_8_11762928_11765191_11857514_11859558_FR CTSB; FDFT1; GATA4; NEIL2; rs1466785; rs804279; rs804270; rs148057216; rs8191664; rs7001819; rs2645429; rs2645424; rs6601615; rs8898; rs762727745; rs13332; rs569307763; rs2740594; rs747940576; rs12338
35 ORF11_10_14255629_14257128_14331424_14334008_FF FRMD4A; rs12220909; rs1218412
36 ORF11_15_26044519_26047445_26072122_26074663_FF rs6576507; rs547843
37 ORF11_16_11953475_11954578_11996894_11999391_FR GSPT1; RP11-166B2.1; SNX29; TNFRSF17; rs12922317
38 ORF11_16_27236516_27245702_27283060_27288284_RF KDM8; NSMCE1; rs9940555
39 ORF11_19_48817066_48819208_48918494_48922385_RR BCAT2; HSD17B14; NUCB1; PLEKHA4; PPP1R15A; TULP2; rs56104184; rs17272694; rs557806; rs595982; rs7260579
40 ORF11_20_20005082_20006543_20078974_20082009_FR CFAP61; CRNKL1  A20; RIN2; rs1057519885
41 ORF11_20_21483562_21487561_21497814_21499630_FF NKX2-2; NKX2-4
42 ORF11_4_166285010_166286178_166311616_166318662_FR rs13113999
43 ORF11_4_37845589_37847420_37859966_37862832_RR GAFA3; PGM2
44 ORF11_X_115875719_115878414_115936015_115945579_RF PLS3; rs201386833
45 ORF110_1_48532003_48539768_48618802_48625969_FR AGBL4; SPATA6; rs2803270
46 ORF111_1_48532003_48539768_48618802_48625969_FF AGBL4; SPATA6; rs2803270
47 ORF112_X_6219982_6227001_6295729_6302842_RF NLGN4X; rs756651509; rs2290488
48 ORF113_17_35163743_35164806_35182581_35189768_RF SLC35G3; UNC45B; rs370424081
49 ORF114_21_29891288_29892971_29934336_29938623_RR GRIK1; rs455804
50 ORF115_7_36953187_36955186_36976432_36980351_RR ELMO1; rs6942726
51 ORF117_5_56056790_56059051_56069488_56074299_RR ANKRD55; rs715180
52 ORF117_7_22390272_22396878_22494715_22499120_FR RAPGEF5; STEAP1B
53 ORF117_8_122799764_122802282_122834548_122836477_RR ZHX2; rs10108684
54 ORF117_8_13602479_13607345_13632064_13635521_RR C8orf48
55 ORF118_9_114547520_114550346_114637124_114640336_RF ATP6V1G1; C9orf91; rs10513249; rs10817638
56 ORF118_X_129688045_129690722_129712806_129719890_FR rs3788853; rs56204867
57 ORF119_18_58181079_58183629_58202022_58205094_RF NEDD4L; rs4149601
58 ORF12_10_3728370_3731203_3766614_3768148_RR KLF6; rs705464
59 ORF12_10_86379474_86383560_86442251_86449187_RF WAPAL; rs7075426; rs731171; rs182554582
60 ORF12_12_10186674_10187896_10218366_10224430_RF GABARAPL1; KLRD1; TMEM52B
61 ORF12_12_82971707_82974166_83009437_83013253_RF TMTC2; rs7961953
62 ORF12_12_83941063_83942894_83954032_83957600_FR rs11116045; rs1545843
63 ORF12_15_91096267_91099737_91157513_91165785_RR SV2B; rs886144
64 ORF12_16_10002949_10008026_10047306_10049395_RF GRIN2A; rs4107019; rs11644461; rs7192557
65 ORF12_2_79968604_79971437_79981700_79985274_FR CTNNA2; rs6752828
66 ORF12_20_10249014_10252827_10332102_10337846_FF SNAP25; rs363043; rs363050; rs362584; rs797044873; rs3787283; rs3746544; rs1051312
67 ORF12_3_159122585_159126737_159171258_159178334_RR IQCJ; IQCJ-SCHIP1; rs13064773
68 ORF12_4_125301039_125303568_125344175_125348116_FR FAT4; rs587777724; rs587777725; rs1039808
69 ORF12_6_41251004_41262260_41306014_41314411_FF TREM1; TREML4; rs74851542; rs2234246; rs6910730; rs2234237; rs3789205; rs9471535
70 ORF12_6_5723608_5725733_5763384_5777490_RF FARS2; rs397514612; rs775690041
71 ORF12_7_69585104_69587963_69646882_69650626_RF AUTS2; rs4718886
72 ORF12_8_93942397_93946048_93985677_93987921_FF PDP1; rs7006531
73 ORF12_X_118654955_118657669_118719838_118725132_RR DOCK11; IL13RA1
74 ORF121_10_62722126_62724612_62762850_62765655_RR rs35306388; rs442309; rs58600253
75 ORF121_4_114660322_114662941_114712388_114716541_RF UGT8; rs78557978
76 ORF123_6_151443530_151449164_151468540_151471174_FR C6orf211; RMND1; rs370863743
77 ORF124_5_42377041_42385919_42424469_42426692_FF GHR; rs6898743
78 ORF124_9_125044256_125047827_125094721_125098576_FF PPP6C; SCAI
79 ORF124_X_44196000_44203617_44233955_44239522_FF EFHC2; rs7055196
80 ORF125_5_141308791_141312972_141341365_141343244_RF PCDHGA1; PCDHGA2; PCDHGA3; TAF7; rs563151485; rs61749035
81 ORF125_6_28490451_28494501_28536924_28541272_FR GPX5; GPX6; rs2394103; rs35701070; rs974334; rs13191038; rs406113; rs6456823; rs11757235
82 ORF126_2_68188547_68193452_68260319_68261595_RF HZGJ; PPP3R1; rs2120335; rs12052801; rs1822469; rs12465425
83 ORF126_5_162107624_162113021_162154110_162157909_RR GABRG2; rs211037; rs397514737; rs121909672; rs1060501889; rs121909674
84 ORF128_3_63280859_63282281_63322701_63329776_FF SYNPR; rs13098482
85 ORF13_1_203216286_203223882_203265130_203266595_RR CHIT1; rs871799; rs3831317; rs2297950; rs137852607
86 ORF13_1_208028237_208035325_208092230_208093532_FR PLXNA2; rs11578508; rs841865; rs752016; rs1327175; rs2478813; rs2498028; rs716461
87 ORF13_12_123039105_123047896_123111911_123114094_FF PITPNM2; rs1727294; rs1727307; rs7132277
88 ORF13_12_22550236_22564251_22589587_22591499_RF C2CD5; ETNK1
89 ORF13_13_52983399_52988983_53034265_53036683_FF OLFM4; rs9568797
90 ORF13_2_11504797_11509096_11532162_11535545_RR E2F6; GREB1; rs77294520
91 ORF13_20_38210518_38212890_38329699_38336059_RR BPI; KIAA1755; rs6024947; rs6123471; rs6127471; rs4811602; rs877600; rs1341023; rs5743507; rs4358188
92 ORF13_4_187957960_187960546_188016179_188019108_FF ZFP42; rs6825162; rs6837349; rs4862848
93 ORF13_6_154259046_154260916_154294994_154298490_RF CNKSR3; IPCEF1; OPRM1
94 ORF13_7_22365643_22368712_22390272_22396878_RF RAPGEF5; STEAP1B
95 ORF13_8_52230322_52233827_52248401_52253166_RF ST18; rs2360806
96 ORF130_2_77483560_77486991_77514867_77519288_FR LRRTM4; rs61354037
97 ORF131_19_9846242_9849549_9869701_9871067_RF OLFM2; PIN1; rs2233682; rs2287838; rs779032127
98 ORF132_5_17887397_17895130_17964289_17970189_RR rs140236920
99 ORF133_10_30527367_30529631_30585089_30589121_RR LYZL2; MAP3K8
100 ORF134_14_68255587_68260022_68325745_68327713_RR RAD51B; rs1570106; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566
101 ORF138_17_35287155_35289074_35314277_35315961_FF SLFN11; SLFN5
102 ORF138_6_151387953_151393542_151443530_151449164_RF C6orf211; RMND1; ZBTB2; rs115079861; rs886037773; rs886037771; rs397515421; rs1057519299; rs773470671; rs144972972; rs771894262; rs606231472; rs886037772; rs370863743
103 ORF138_6_169185535_169187937_169230654_169232256_FR THBS2; rs9406328
104 ORF139_14_51886119_51892276_51935246_51939339_FF GNG2; rs8015138
105 ORF14_1_110155952_110164041_110184326_110187411_FF SLC6A17; rs375380880; rs775085213
106 ORF14_1_76048774_76050727_76086337_76098934_RF ST6GALNAC3; rs915404
107 ORF14_18_23965423_23972468_24001102_24007770_RF LAMA3; TTC39C
108 ORF14_3_159142637_159144036_159166834_159171258_RF IQCJ; IQCJ-SCHIP1; rs13064773
109 ORF14_3_159142637_159144036_159171258_159178334_RR IQCJ; IQCJ-SCHIP1; rs13064773
110 ORF14_4_152216416_152218364_152243834_152246201_FR FBXW7; rs522743
111 ORF14_4_187957960_187960546_188016179_188019108_FF ZFP42; rs6825162; rs6837349; rs4862848
112 ORF14_8_65603423_65608237_65633322_65635344_FR ARMC1; MTFR1
113 ORF14_9_114559604_114561408_114637124_114640336_RF ATP6V1G1; C9orf91; rs10513249; rs10817638
114 ORF141_9_33273553_33275175_33317596_33319558_FR BAG1; CHMP5; NFX1
115 ORF141_X_40497397_40499087_40520869_40522158_FR BCOR; rs2968915
116 ORF142_X_40497397_40499087_40520869_40522158_FF BCOR; rs2968915
117 ORF143_7_36953187_36955186_36980351_36983506_RR ELMO1; rs6942726
118 ORF144_14_91001527_91004763_91060989_91062696_RR C14orf159; RPS6KA5; rs1286150; rs11848357
119 ORF144_2_167702360_167710563_167770932_167773324_RF rs971257; rs116677506
120 ORF144_2_44766242_44769058_44787731_44792832_RF CAMKMT; SIX3
表4.a1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
1 NA NA NA
2 18; 18 1; 1 0.357137933; 0.357137933
3 55 1 0.250357845
4 94; 90 3; 1; 3; 1 0.213331923; 0.072103962; 0.219233776; 0.082047788
5 16; 26 1; 2; 1 0.343724359; 0.19032457; 0.373699919
6 47 1 0.29419612
7 45 6; 1 0.006017292; 0.285503815
8 45 6; 1 0.006017292; 0.285503815
9 45 6; 1 0.006017292; 0.285503815
10 72 5 0.087766242
11 72 5 0.087766242
12 72 5 0.087766242
13 63; 57 3; 3; 3; 3 0.216848517; 0.224771745; 0.202795213; 0.214348844
14 68 8 0.005458299
15 49; 68; 56 4; 8; 4 0.096088025; 0.005458299; 0.123346872
16 190 5; 4  0.112399625; 0.054978865
17 51 1 0.249886334
18 18 1 0.357137933
19 14 2 0.096260668
20 57 1 0.239596043
21 30 4; 5 0.022454364; 0.006393518
22 21 1 0.369816322
23 37; 37 5; 8; 5; 8 0.010942367; 0.000107113; 0.010942367; 0.000107113
24 9; 34 1; 2; 1; 2 0.255358235; 0.047199169; 0.357029649; 0.251319324
25 24 1 0.375945017
26 8; 17; 21 1; 2; 2 0.249326315; 0.126473611; 0.164464127
27 94; 90 3; 1; 3; 1 0.213331923; 0.072103962; 0.219233776; 0.082047788
28 63; 46; 75 3; 5; 2; 4; 3; 5 0.216848517; 0.076682692; 0.273777277; 0.084172061; 0.228845362; 0.1125292
29 8 1 0.249326315
30 2 1 0.074939792
31 38 2; 1 0.255573168; 0.325888812
32 NA NA NA
33 15 2; 1 0.095167761; 0.346011739
34 52; 53; 21; 42 1; 1; 1; 1 0.244043749; 0.238249082; 0.37425716; 0.303213711
35 107 3; 2  0.188257442; 0.10954189
36 NA NA NA
37 18; 46; 103; 18 1; 1; 1; 3; 1 0.357137933; 0.299630226; 0.069157027; 0.178958558; 0.357137933
38 40; 62 1; 1 0.330827809; 0.213548789
39 7; 19; 59; 59; 62; 58 1; 1; 1; 1; 1; 1 0.215038813; 0.362286681; 0.229012733; 0.229012733; 0.213548789; 0.234279681
40 15; 17; 104; 175 1; 1; 1; 1; 1; 1; 4; 4 0.335307856; 0.346011739; 0.350975055; 0.359834557; 0.067095696; 0.05179789; 0.096861772; 0.075450093
41 90; 51 1; 1 0.101520575; 0.272236181
42 NA NA NA
43 37; 37 5; 8; 5; 8 0.010942367; 0.000107113; 0.010942367; 0.000107113
44 29 2; 5  0.211050406; 0.005560973
45 93; 9 1; 5; 4 0.093070545; 0.156450038; 0.000317369
46 93; 9 1; 5; 4 0.093070545; 0.156450038; 0.000317369
47 31 1 0.359323344
48 38; 51 1; 1 0.340322106; 0.272236181
49 9 1 0.255358235
50 135 4; 2  0.167299602; 0.052146884
51 72 5 0.087766242
52 107; 149 3; 3 0.188257442; 0.096032365
53 69 1 0.155641612
54 8 2; 1 0.033505489; 0.249326315
55 113; 113 1; 1; 1; 1 0.050893345; 0.038148244; 0.050893345; 0.038148244
56 NA NA NA
57 33 4; 2 0.029769861; 0.246924146
58 53 1 0.238249082
59 78 1 0.141989949
60 29; 26; 59 2; 2; 2; 1; 2; 2 0.211050406; 0.22548219; 0.19032457; 0.373699919; 0.269881341; 0.261532562
61 27 2; 1 0.197546356; 0.37173223
62 NA NA NA
63 14 2 0.096260668
64 105 2; 1 0.137861813; 0.050084955
65 40 2; 3 0.261899069; 0.150241062
66 63 1 0.184056651
67 22; 33 3; 3 0.042821316; 0.098061922
68 19 3; 4 0.030348034; 0.006361707
69 39; 29 1; 1 0.320372604; 0.366349054
70 37 1; 2 0.34481748; 0.262259643
71 83 1 0.123780263
72 38 2; 1  0.255573168; 0.325888812
73 13; 13 1; 2 0.314642613; 0.076537269
74 NA NA NA
75 7 1 0.227740664
76 63; 75 3; 5; 3; 5 0.216848517; 0.076682692; 0.228845362; 0.1125292
77 16 1; 2  0.343724359; 0.116490918
78 21; 18 1; 1 0.37425716; 0.364965787
79 23 1 0.374075448
80 41; 33; 31; 26 1; 1; 1; 1 0.309016356; 0.35096223; 0.359323344; 0.373699919
81 34; 20 1; 1 0.346365974; 0.372098641
82 9; 4 1; 1 0.268692312; 0.14804367
83 6 1 0.203777963
84 41 2; 1 0.26460109; 0.309016356
85 10 1 0.285987033
86 69 1 0.155641612
87 62 1 0.213548789
88 11; 9 1; 1 0.301350316; 0.268692312
89 26 2 0.205329626
90 48; 40 4; 1; 4; 1 0.078104352; 0.267628012; 0.050377953; 0.314741981
91 77; 57 1; 1 0.123007769; 0.215667339
92 29 1; 1 0.371537436; 0.366349054
93 163; 163; 140 4; 2; 4; 2; 4; 2 0.117375195; 0.022678142; 0.117375195; 0.022678142; 0.158806697; 0.045194146
94 107; 149 3; 3 0.188257442; 0.096032365
95 78 2; 4 0.222357541; 0.186212358
96 9 3; 2 0.00391071; 0.047199169
97 149; 153 1; 1 0.015913046; 0.013923327
98 NA NA NA
99 68; 53 1; 1 0.184410962; 0.261255041
100 17 3; 2 0.023054538; 0.126473611
101 22; 26 1; 1 0.375573766; 0.373699919
102 63; 75; 76 3; 5; 3; 5; 1 0.216848517; 0.076682692; 0.228845362; 0.1125292; 0.149832643
103 46 2; 3 0.273777277; 0.178397403
104 36 2; 3 0.247980559; 0.12891994
105 68 8 0.005458299
106 45 5; 5 0.022343156; 0.028833151
107 82; 83 1; 2; 1 0.127264367; 0.188524907; 0.102353336
108 22; 33 3; 3 0.042821316; 0.098061922
109 22; 33 3; 3 0.042821316; 0.098061922
110 143 3; 2 0.107765005; 0.041422991
111 29 1; 1 0.371537436; 0.366349054
112 48; 28 5; 4; 2; 1 0.02780594; 0.092112824; 0.204457601; 0.369266824
113 113; 113 1; 1; 1; 1 0.050893345; 0.038148244; 0.050893345; 0.038148244
114 12; 22; 28 4; 1; 5; 1; 5; 1 0.000827358; 0.314913912; 0.001196845; 0.375573766; 0.003522831; 0.369266824
115 3 3; 1 5.91e-05; 0.042102538
116 3 3; 1 5.91e-05; 0.042102538
117 135 4; 2 0.167299602; 0.052146884
118 24; 88 1; 2 0.375945017; 0.167789783
119 NA NA NA
120 16; 16 1; 1 0.343724359; 0.343724359
表4.a2
   FDR_HyperG Percent_Sig logFC AveExpr
1 NA NA 0.512391512 0.512391512
2 0.375519541; 0.375519541 5.56; 5.56 0.554083838 0.554083838
3 0.375519541 1.82 0.495818977 0.495818977
4 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.19; 1.06; 3.33; 1.11 0.549448158 0.549448158
5 0.375519541; 0.375519541; 0.376115439 6.25; 7.69; 3.85 0.548142412 0.548142412
6 0.375519541 2.13 0.500436606 0.500436606
7 0.242080288; 0.376115439 13.33; 2.22 0.498976751 0.498976751
8 0.242080288; 0.376115439 13.33; 2.22 0.530470107 0.530470107
9 0.242080288; 0.376115439 13.33; 2.22 0.505696778 0.505696778
10 0.375519541 6.94 0.519474296 0.519474296
11 0.375519541 6.94 0.513921274 0.513921274
12 0.375519541 6.94 0.492941201 0.492941201
13 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 4.76; 5.26; 5.26 0.498701064 0.498701064
14 0.217379602 11.76 0.591810053 0.591810053
15 0.376115439; 0.217379602; 0.376115439 8.16; 11.76; 7.14 0.506870902 0.506870902
16 0.375519541; 0.376115439 2.63; 2.11 0.53203974 0.53203974
17 0.376115439 1.96 0.535671314 0.535671314
18 0.375519541 5.56 0.560634913 0.560634913
19 0.376115439 14.29 0.538523405 0.538523405
20 0.375519541 1.75 0.581440892 0.581440892
21 0.375519541; 0.217379602 13.33; 16.67 0.542968688 0.542968688
22 0.375519541 4.76 0.495604879 0.495604879
23 0.357678624; 0.013656923; 0.357678624; 0.013656923 13.51; 21.62; 13.51; 21.62 0.56026758 0.56026758
24 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 22.22; 2.94; 5.88 0.50907406 0.50907406
25 0.376115439 4.17 0.514728586 0.514728586
26 0.376115439; 0.376115439; 0.376115439 12.5; 11.76; 9.52 0.558078621 0.558078621
27 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.19; 1.06; 3.33; 1.11 0.555500586 0.555500586
28 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 7.94; 4.35; 8.7; 4; 6.67 0.506064368 0.506064368
29 0.376115439 12.5 0.528154277 0.528154277
30 0.375519541 50 0.521562164 0.521562164
31 0.375519541; 0.376115439 5.26; 2.63 0.494634685 0.494634685
32 NA NA 0.546740356 0.546740356
33 0.375519541; 0.376115439 13.33; 6.67 0.547454292 0.547454292
34 0.376115439; 0.376115439; 0.376115439; 0.376115439 1.92; 1.89; 4.76; 2.38 0.569015638 0.569015638
35 0.375519541; 0.376115439 2.8; 1.87 0.522699551 0.522699551
36 NA NA 0.496476276 0.496476276
37 0.375519541; 0.375519541; 0.375519541; 0.376115439; 0.375519541 5.56; 2.17; 0.97; 2.91; 5.56 0.552736089 0.552736089
38 0.375519541; 0.375519541 2.5; 1.61 0.499371507 0.499371507
39 0.375519541; 0.375519541; 0.375519541; 0.375519541; 0.375519541; 0.375519541 14.29; 5.26; 1.69; 1.69; 1.61; 1.72 0.533451866 0.533451866
40 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.67; 6.67; 5.88; 5.88; 0.96; 0.96; 2.29; 2.29 0.50671489 0.50671489
41 0.375519541; 0.375519541 1.11; 1.96 0.500870049 0.500870049
42 NA NA 0.542666527 0.542666527
43 0.357678624; 0.013656923; 0.357678624; 0.013656923 13.51; 21.62; 13.51; 21.62 0.568391567 0.568391567
44 0.375519541; 0.217379602 6.9; 17.24  0.558239253 0.558239253
45 0.375519541; 0.376115439; 0.029015407 1.08; 5.38; 44.44 0.643128478 0.643128478
46 0.375519541; 0.376115439; 0.029015407  1.08; 5.38; 44.44 0.648504396 0.648504396
47 0.376115439 3.23 0.687940877 0.687940877
48 0.375519541; 0.375519541 2.63; 1.96 0.522128489 0.522128489
49 0.375519541 11.11 0.521897056 0.521897056
50 0.375519541; 0.376115439 2.96; 1.48 0.632249447 0.632249447
51 0.375519541 6.94 0.496055077 0.496055077
52 0.375519541; 0.375519541 2.8; 2.01 0.847682313 0.847682313
53 0.376115439 1.45 0.526831442 0.526831442
54 0.375519541; 0.376115439 25; 12.5 0.602529816 0.602529816
55 0.375519541; 0.376115439; 0.375519541; 0.376115439 0.88; 0.88; 0.88; 0.88 0.523498591 0.523498591
56 NA NA 0.493252598 0.493252598
57 0.375519541; 0.376115439  12.12; 6.06  0.495719643 0.495719643
58 0.376115439 1.89 0.538330172 0.538330172
59 0.375519541 1.28 0.601783589 0.601783589
60 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 6.9; 6.9; 7.69; 3.85; 3.39; 3.39 0.525962054 0.525962054
61 0.375519541; 0.376115439  7.41; 3.7  0.525549931 0.525549931
62 NA NA 0.557788433 0.557788433
63 0.376115439 14.29 0.525324032 0.525324032
64 0.375519541; 0.376115439 1.9; 0.95  0.621088697 0.621088697
65 0.375519541; 0.376115439 5; 7.5  0.677723011 0.677723011
66 0.376115439 1.59 0.53163061 0.53163061
67 0.375519541; 0.375519541 13.64; 9.09 0.536635995 0.536635995
68 0.375519541; 0.217379602 15.79; 21.05 0.578945234 0.578945234
69 0.376115439; 0.376115439 2.56; 3.45 0.505795513 0.505795513
70 0.375519541; 0.376115439 2.7; 5.41 0.529076251 0.529076251
71 0.375519541 1.2 0.493021263 0.493021263
72 0.375519541; 0.376115439 5.26; 2.63 0.519212964 0.519212964
73 0.375519541; 0.375519541 7.69; 15.38 0.610109081 0.610109081
74 NA NA 0.569951514 0.569951514
75 0.376115439 14.29 0.507308688 0.507308688
76 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 7.94; 4; 6.67 0.529494353 0.529494353
77 0.375519541; 0.376115439 6.25; 12.5 0.615759002 0.615759002
78 0.376115439; 0.376115439 4.76; 5.56 0.543830358 0.543830358
79 0.375519541 4.35 0.552021975 0.552021975
80 0.376115439; 0.376115439; 0.376115439; 0.376115439 2.44; 3.03; 3.23; 3.85 0.511462115 0.511462115
81 0.376115439; 0.376115439 2.94; 5 0.606358104 0.606358104
82 0.376115439; 0.376115439 11.11; 25 0.536517858 0.536517858
83 0.376115439 16.67 0.560038868 0.560038868
84 0.375519541; 0.376115439 4.88; 2.44 0.515514819 0.515514819
85 0.376115439 10 0.52699264 0.52699264
86 0.376115439 1.45 0.561634704 0.561634704
87 0.375519541 1.61 0.516227401 0.516227401
88 0.376115439; 0.376115439 9.09; 11.11 0.708307997 0.708307997
89 0.376115439 7.69 0.515116689 0.515116689
90 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.33; 2.08; 10; 2.5 0.527088069 0.527088069
91 0.376115439; 0.376115439 1.3; 1.75 0.50771261 0.50771261
92 0.375519541; 0.376115439 3.45; 3.45 0.515351129 0.515351129
93 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 2.45; 1.23; 2.45; 1.23; 2.86; 1.43 0.606390225 0.606390225
94 0.375519541; 0.375519541 2.8; 2.01 0.681358183 0.681358183
95 0.375519541; 0.376115439 2.56; 5.13 0.54340267 0.54340267
96 0.185936467; 0.376115439 33.33; 22.22 0.704110059 0.704110059
97 0.375519541; 0.375519541 0.67; 0.65 0.558359682 0.558359682
98 NA NA 0.56685989 0.56685989
99 0.375519541; 0.375519541 1.47; 1.89 0.53718766 0.53718766
100 0.375519541; 0.376115439 17.65; 11.76 0.511127208 0.511127208
101 0.376115439; 0.376115439 4.55; 3.85 0.51729912 0.51729912
102 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541 4.76; 7.94; 4; 6.67; 1.32 0.499796862 0.499796862
103 0.375519541; 0.376115439 4.35; 6.52 0.54284743 0.54284743
104 0.375519541; 0.376115439 5.56; 8.33 0.541515701 0.541515701
105 0.217379602 11.76 0.535653111 0.535653111
106 0.375519541; 0.376115439 11.11; 11.11  0.5892727 0.5892727
107 0.375519541; 0.376115439; 0.376115439 1.22; 2.44; 1.2 0.51370343 0.51370343
108 0.375519541; 0.375519541 13.64; 9.09 0.53237946 0.53237946
109 0.375519541; 0.375519541 13.64; 9.09 0.537399464 0.537399464
110 0.375519541; 0.376115439 2.1; 1.4 0.551147909 0.551147909
111 0.375519541; 0.376115439 3.45; 3.45 0.51123955 0.51123955
112 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.42; 8.33; 7.14; 3.57 0.565781874 0.565781874
113 0.375519541; 0.376115439; 0.375519541; 0.376115439 0.88; 0.88; 0.88; 0.88 0.643607703 0.643607703
114 0.069549998; 0.376115439; 0.069549998; 0.376115439; 0.184244052; 0.376115439 33.33; 8.33; 22.73; 4.55; 17.86; 3.57 0.669167007 0.669167007
115 0.007721092; 0.376115439 100; 100  0.569124095 0.569124095
116 0.007721092; 0.376115439 100; 100 0.504949853 0.504949853
117 0.375519541; 0.376115439 2.96; 1.48 0.574029643 0.574029643
118 0.376115439; 0.376115439 4.17; 2.27 0.51834761 0.51834761
119 NA NA 0.589448815 0.589448815
120 0.375519541; 0.375519541 6.25; 6.25 0.559224072 0.559224072
表4.a3
   t P值 adj.P.Val B FC FC_1 LS
1 11.41870737 0.0000000852 0.00000896 8.502768427 1.426412758 1.426412758 1
2 11.44997197 0.0000000827 0.00000883 8.533074362 1.468235956 1.468235956 1
3 13.35488716 0.0000000148 0.00000349 10.24087961 1.410121014 1.410121014 1
4 5.995732933 0.000063 0.000599458 1.735098705 1.463525779 1.463525779 1
5 12.11509752 0.0000000442 0.00000625 9.159529569 1.462201779 1.462201779 1
6 6.872082789 0.0000173 0.00025065 3.070157579 1.414641614 1.414641614 1
7 7.910034004 0.00000426 0.0000997 4.516650735 1.41321087 1.41321087 1
8 8.959263256 0.00000117 0.000044 5.843091809 1.444399781 1.444399781 1
9 6.219486663 0.0000448 0.000471751 2.086224451 1.419808915 1.419808915 1
10 6.720085442 0.0000215 0.000289033 2.846273777 1.433432824 1.433432824 1
11 7.35826499 0.00000883 0.00015988 3.765261563 1.427926058 1.427926058 1
12 8.137081873 0.00000319 0.0000826 4.814738224 1.407311017 1.407311017 1
13 10.81146677 0.000000155 0.0000128 7.898019883 1.412940842 1.412940842 1
14 14.58929087 0.00000000570 0.00000418 11.13259491 1.507136465 1.507136465 1
15 12.77090209 0.0000000255 0.00000896 9.696346675 1.420964884 1.420964884 1
16 9.293886644 0.000000795 0.0000347 6.239911385 1.445972124 1.445972124 1
17 6.624725473 0.0000251 0.000578066 2.76246354 1.449616533 1.449616533 1
18 8.382200009 0.00000235 0.0000683 5.129546721 1.474918169 1.474918169 1
19 7.979860208 0.00000399 0.000176719 4.646990654 1.452485141 1.452485141 1
20 10.10136035 0.000000325 0.0000199 7.149689173 1.496342976 1.496342976 1
21 6.688687973 0.0000229 0.000544563 2.856999798 1.456967492 1.456967492 1
22 8.134319545 0.0000032 0.0000828 4.811149443 1.409911765 1.409911765 1
23 7.900221709 0.00000442 0.000188752 4.542868458 1.474542679 1.474542679 1
24 6.947739296 0.0000159 0.000426833 3.234059599 1.423136515 1.423136515 1
25 3.331776907 0.006019015 0.025782104 -2.830634507 1.428725328 1.428725328 1
26 7.104660514 0.0000128 0.000368882 3.457978296 1.472307095 1.472307095 1
27 6.228318665 0.0000443 0.000467151 2.099938796 1.469678494 1.469678494 1
28 12.67188628 0.0000000279 0.00000925 9.611921232 1.42017072 1.42017072 1
29 6.907694762 0.0000168 0.000443936 3.17637888 1.442083074 1.442083074 1
30 11.98944945 0.0000000496 0.00000664 9.043800442 1.435508789 1.435508789 1
31 5.855905908 0.0000781 0.000696337 1.512075209 1.408963936 1.408963936 1
32 11.91777496 0.000000053 0.00000684 8.977248932 1.460781455 1.460781455 1
33 15.57287232 0.00000000258 0.00000143 11.93541682 1.461504521 1.461504521 1
34 7.053243734 0.0000137 0.000387816 3.384978548 1.483511014 1.483511014 1
35 6.170784518 0.0000483 0.000496728 2.010401724 1.436640957 1.436640957 1
36 5.063978273 0.000279288 0.001735541 0.197313651 1.410763618 1.410763618 1
37 9.323393292 0.000000768 0.0000341 6.274327924 1.466864988 1.466864988 1
38 5.592169596 0.000118264 0.000931355 1.083895875 1.413597611 1.413597611 1
39 9.514080591 0.000000619 0.0000296 6.494550787 1.44738815 1.44738815 1
40 7.45936797 0.00000788 0.000271057 3.951910034 1.420811231 1.420811231 1
41 8.790634074 0.00000143 0.0000501 5.638482912 1.415066693 1.415066693 1
42 11.02640152 0.000000125 0.0000112 8.115640908 1.456662374 1.456662374 1
43 10.05471731 0.000000353 0.0000392 7.101969519 1.482869426 1.482869426 1
44 3.549463521 0.004032097 0.019123986 -2.429239653 1.472471033 1.472471033 1
45 7.127692941 0.0000124 0.000361932 3.490562728 1.561712056 1.561712056 1
46 6.776432481 0.0000202 0.000503209 2.985756907 1.567542324 1.567542324 1
47 7.312780139 0.0000096 0.000307939 3.749817999 1.610982562 1.610982562 1
48 8.627862485 0.00000174 0.0000567 5.437954357 1.436072404 1.436072404 1
49 2.879175397 0.013870748 0.033607862 -3.760402038 1.435842052 1.435842052 1
50 7.686493693 0.0000057 0.000120419 4.216916567 1.549979836 1.549979836 1
51 3.873638586 0.002219338 0.008089367 -1.925126481 1.410351802 1.410351802 1
52 2.799977556 0.016065387 0.037943829 -3.904564952 1.799607536 1.799607536 1
53 4.829381768 0.000418663 0.00396156 -0.127073912 1.440761407 1.440761407 1
54 11.65995884 0.0000000676 0.00000784 8.734586918 1.51837676 1.51837676 1
55 6.719932103 0.0000215 0.000289074 2.846046312 1.437436864 1.437436864 1
56 7.205917646 0.0000109 0.000183806 3.550848217 1.407614809 1.407614809 1
57 9.703470008 0.000000502 0.0000259 6.709574897 1.410023926 1.410023926 1
58 10.42145474 0.00000024 0.0000316 7.489206383 1.45229061 1.45229061 1
59 14.29981241 0.00000000683 0.00000239 10.99743706 1.51759159 1.51759159 1
60 20.73578644 0.0000000000937 0.00000039 14.98984912 1.439893446 1.439893446 1
61 9.234179531 0.000000851 0.0000362 6.16998741 1.439482182 1.439482182 1
62 7.889911948 0.00000448 0.000190333 4.529331111 1.47201098 1.47201098 1
63 8.897471193 0.0000013 0.0000874 5.791565108 1.439256803 1.439256803 1
64 11.6462149 0.0000000685 0.00000792 8.721505014 1.538035387 1.538035387 1
65 6.080930527 0.0000562 0.000988559 1.935395629 1.599613111 1.599613111 1
66 13.56030744 0.000000013 0.00000631 10.34557005 1.445562123 1.445562123 1
67 9.911003735 0.0000004 0.0000225 6.941066482 1.450586165 1.450586165 1
68 8.045227884 0.00000367 0.000168145 4.731865147 1.493756752 1.493756752 1
69 7.253805221 0.0000104 0.000323479 3.667708828 1.419906087 1.419906087 1
70 8.402676813 0.00000235 0.000126478 5.186755121 1.443004952 1.443004952 1
71 7.591037902 0.00000647 0.000130639 4.08699801 1.407389118 1.407389118 1
72 14.65514231 0.00000000517 0.00000209 11.2681905 1.433173193 1.433173193 1
73 10.41656381 0.000000233 0.0000163 7.487562094 1.526374612 1.526374612 1
74 11.44449067 0.0000000862 0.0000169 8.505212327 1.48447368 1.48447368 1
75 9.311645565 0.000000802 0.0000646 6.276707204 1.421396141 1.421396141 1
76 15.47686276 0.00000000291 0.00000295 11.76272323 1.443423204 1.443423204 1
77 7.915322211 0.00000434 0.000186551 4.562672286 1.532363961 1.532363961 1
78 9.472837646 0.000000669 0.0000578 6.460535766 1.457837946 1.457837946 1
79 9.95953215 0.000000379 0.0000218 6.99458501 1.466139089 1.466139089 1
80 10.50670556 0.00000022 0.00003 7.577414801 1.425494146 1.425494146 1
81 10.55449174 0.000000209 0.000029 7.626566681 1.522411225 1.522411225 1
82 5.940288146 0.0000697 0.001143512 1.71463084 1.450467388 1.450467388 1
83 7.028930184 0.0000142 0.000396157 3.350333903 1.474308937 1.474308937 1
84 10.64769999 0.000000184 0.0000142 7.729497708 1.42950416 1.42950416 1
85 7.903107235 0.0000044 0.000188471 4.546654942 1.440922398 1.440922398 1
86 5.619206152 0.000114904 0.001606096 1.200035669 1.475940644 1.475940644 1
87 10.57812691 0.000000197 0.0000149 7.657182201 1.430210401 1.430210401 1
88 13.55522334 0.0000000131 0.00000631 10.34151993 1.633886759 1.633886759 1
89 7.780242064 0.00000516 0.000208179 4.384499004 1.429109726 1.429109726 1
90 9.782590932 0.00000046 0.0000246 6.7983337 1.441017712 1.441017712 1
91 10.40776596 0.000000243 0.0000318 7.47498009 1.421794155 1.421794155 1
92 7.591517206 0.00000661 0.000240958 4.131679589 1.429341977 1.429341977 1
93 11.41759539 0.0000000853 0.00000896 8.501689081 1.522445121 1.522445121 1
94 2.6388933 0.021641591 0.048298429 -4.195118121 1.603648753 1.603648753 1
95 10.63254592 0.000000193 0.0000277 7.706404143 1.457405833 1.457405833 1
96 7.388506697 0.00000848 0.000155513 3.807459974 1.629139404 1.629139404 1
97 8.388740018 0.00000233 0.000068 5.137848331 1.472593953 1.472593953 1
98 19.080395 0.000000000262 0.00000103 13.93674337 1.481295932 1.481295932 1
99 7.477753822 0.00000752 0.000143556 3.931296311 1.451140955 1.451140955 1
100 6.947386003 0.0000156 0.000233679 3.179903542 1.425163271 1.425163271 1
101 8.48815395 0.00000212 0.000119002 5.293265639 1.431273241 1.431273241 1
102 8.595925108 0.00000181 0.0000579 5.39825467 1.414014449 1.414014449 1
103 5.759469074 0.0000922 0.001381184 1.426643373 1.456845039 1.456845039 1
104 7.831384519 0.00000483 0.000199439 4.452227696 1.455500869 1.455500869 1
105 11.64034791 0.0000000715 0.0000151 8.689620149 1.449598242 1.449598242 1
106 6.658579921 0.0000239 0.00056116 2.812571543 1.504488105 1.504488105 1
107 7.843278039 0.00000476 0.000197838 4.467931038 1.42771046 1.42771046 1
108 5.251373348 0.000204975 0.001381445 0.51621616 1.446312656 1.446312656 1
109 8.332012005 0.0000025 0.0000709 5.065672258 1.451354014 1.451354014 1
110 11.55832367 0.0000000773 0.000016 8.612768013 1.465251089 1.465251089 1
111 10.39410543 0.000000239 0.0000166 7.463794895 1.425274252 1.425274252 1
112 8.714863889 0.00000157 0.0000531 5.545510389 1.480189486 1.480189486 1
113 7.197536867 0.0000112 0.000340019 3.588934493 1.562230902 1.562230902 1
114 5.877052051 0.0000756 0.000680344 1.545980911 1.590154568 1.590154568 1
115 8.969566368 0.00000116 0.0000437 5.855491205 1.483622544 1.483622544 1
116 6.452593491 0.0000317 0.000372647 2.44450975 1.419074029 1.419074029 1
117 7.828142943 0.00000474 0.000106901 4.407574969 1.488675843 1.488675843 1
118 4.565789484 0.000656977 0.005449274 -0.588131844 1.432313809 1.432313809 1
119 8.468189927 0.00000217 0.000120651 5.268466147 1.504671774 1.504671774 1
120 7.905614338 0.00000429 0.000100071 4.510785229 1.47347652 1.47347652 1
表4.a4
      探針序列 探針位置
偵測到之環 60 mer Chr
1 sHC TCTCTTCTAAAGAATGTTAAATAAATATTCGAACATTCCAAAATGCAGAGATACTCATGG 1
2 sHC TGTCTAAAAAGTAAAAAAGAATATTGGCTCGATGATACTTAAATTTTTGGTCAGAACAGG 10
3 sHC AGCAGGAGGATCATCTGAGCTCAGTAGTTCGAACCTCATGTTTAGGGCCCAGCAAGTCCC 12
4 sHC CAATAAAAATGAATGCTTAGTAAATCCATCGAGGCCGCAGTGAGCTATGACTGAGCCACC 14
5 sHC GAGGCTGAGATATGAGGATCTCTTGAACTCGAATTCCAGTGTCTATAAATAAAGTTTTAT 16
6 sHC TTGTCCTCATTATTATTCTTTCTAATACTCGAGATATAATTTACATATCATACAATTCAT 2
7 sHC GGCCGGCAGATCACTTCAGGTCAAGAGTTCGACTTCCTTAAAGTTTCATTTTGATGAAGT 21
8 sHC GGCCGGCAGATCACTTCAGGTCAAGAGTTCGATGATGATATAGGCATTAAAACATGAGTT 21
9 sHC TTTTTATTTTATCTTTTATTTTATTTTTTCGAAGTATTACTATTCTCACTTTATAGATGA 21
10 sHC GGCAGGTGAATCAGCTGAGTTCAGGAGTTCGATGTGGGTCTTGGAACATATCCCCTCCAG 5
11 sHC GGCAGGTGAATCAGCTGAGTTCAGGAGTTCGATTCCACATAATCTCTTCCAAAAAGAAGA 5
12 sHC GGCAGGTGAATCAGCTGAGTTCAGGAGTTCGATTAGCCCAGTATCTCATTGCTGTATCTT 5
13 sHC CAAAGCTGAAAGCTTACACTTCATTGAATCGAAAATGCATTTCTTATGTTACTGTCTTGT 8
14 mHC GTATCACCCCTGGCCATTACATTATCCATCGATAAGGATTCTATAGAGTCAGATTCTCTA 1
15 mHC GTATCACCCCTGGCCATTACATTATCCATCGACCTCCCAAAGAGACAATTGTTTTTTAAA 1
16 sHC ATGTATTTTTCACAATATGAATTAAAAGTCGACTCATTTTCATCTGAAAAGCCTGTTTAG 10
17 mHC ATTACATTTCATATATTTCAGTCCATTTTCGAAATAATACAACCGTTTGTCTCTTATCTA 10
18 sHC CTTAAAGATAAACAATATGTGTATTAACTCGATGATATCTGCATTAATTTTTAAATTTGA 11
19 mHC TTCAACAGTCATACATATTTTAAAGAATTCGAAATAAGTTTTATTTTGATACTGATATAA 15
20 sHC AGCAGATGGATCACATGAGGTCAGGAGTTCGAACTTCTGACCTCAGGTGATACACCTGCC 16
21 mHC TTTAAAATTGTTGACAGAAAATATATTATCGATAACATCTTGACAGAGTTAAAGTTTCAA 3
22 sHC CTATTCTAAGGATATACTTGAACTATAATCGAATTATGTCTGCTTAAAAGTCTGGTACAA 3
23 mHC TGAAAATAAAAGATTATTTAATCAAGAATCGATATATTCTACAAACTGCTTTATTGTAGA 4
24 mHC TTAAATGTACCAATCTTTTATTTTATAGTCGAGAAAAGTCTGAACTAAATCTGTTAAGGT X
25 mHC TCAGAGTTGGAAGTACCCTTAAAGGCCATCGAGCGTTTTATGTGGACTCTCCTTTTTTCT X
26 mHC ACAGGTATTAGGGTGTTTATTTTGCTTCTCGATTCAAAAGGGCAGATAATTTTGGAGCAA 12
27 sHC CAATAAAAATGAATGCTTAGTAAATCCATCGAGGCCGCAGTGAGCTATGACTGAGCCACC 14
28 mHC GAGGCGGGTGATTCACAAGGTCAGATGTTCGAAAATTAATTTTATGTCTGTGGCTTCTAA 6
29 mHC TTTTTAGTTTGATTATAGTTTATAATAATCGACTCTTTCCCAGTAATCTACTAGGTAATT 3
30 sHC AGTATATCTACAATACACATACTGTGAATCGAATGTTTCCCTGGGATTTTTGGACTTTCA 15
31 sHC AGCAGGTGGATCACCTGCGGTCAGGAGTTCGATGGGAAACTAATCAATAAGAAATTAGAT 16
32 sHC GAGTAATTCACCAAAGTCACAAATTCACTCGACACTCCAGAGATTGTGAATGTCCTTTTA 9
33 sHC TGTAAAGTTTTCATATATAAAATCAAATTCGACAACAGGGTAAGGGTTAGAACCCAAGTT 6
34 mHC TCTCAAAAAAAAAAAAAAAATTGGTGTCTCGAGGATGGGAGCGTTTCCATGGCAACTTGA 8
35 sHC ATGGGATGGATCACTTGAGATAAGGAGTTCGATGCTTGGAGCTGTAGAAGTAAACAGAGA 10
36 sHC GGCAGGTGGACAACCTGAGGTCAGGAGTTCGATCTCCTGACCTCATGATTCCCCTGCCTC 15
37 sHC TAAAATTTTTTTTAAGAAGAAAAAAGACTCGAAACCTCTTCCAGAAAAAAATACTAACGG 16
38 sHC AGCAGATGGATCACATGAGGTCAGGAGTTCGATCTCCTGACCTCAAGTGTTCCGCCCACC 16
39 sHC GCCAGGCAGATCATGTGAGATCAGGAGTTCGAACCCTCCCTTTGATCTATTCCATTCTCA 19
40 mHC AATGTTACTTATTATGATTATTAGATAATCGATAAATCTAACAATTTAGATAAAAATGGG 20
41 sHC TTATCTTTATAAATCATACCATATAGCTTCGAGGAACTGATCTTTAATTTTTCTTTAATT 20
42 sHC AGAGCAATAATAATATCTATGACCAATATCGAACTCAGGGAAATTAATGTTTGAAGAGTT 4
43 mHC TGAAAATAAAAGATTATTTAATCAAGAATCGATTAGGATGGAGAATAGTAACACAAAATT 4
44 mHC CACACTTGAGCTCATTGTAAACCAAAGCTCGAGAGCGGTCCCGTGGGGGCGGTGTTACTC X
45 mHC CTGCAGGTGTGTGCATTAAGGAGCAACTTCGAACCAACGTTTCTTACAGTGGTCGGGGGA 1
46 mHC CTGCAGGTGTGTGCATTAAGGAGCAACTTCGAGATGGTTTATGAAACTTTAAGGAATTTT 1
47 mHC GCTATTTTTAGTGAGTGCCTGGGTATATTCGACAAAAACATACAGGCACCTGTGAGCTTT X
48 sHC ATGCCATTCTTTTGTTTTCTTTTGTTTTTCGACTAGTCCTGATTTTGTACACATGAAAAT 17
49 sHC TTTTATGTATGATATTTGCGTGAGATTCTCGATTTCCACTTAGTACACACAGTGAAAGGG 21
50 sHC AGGTGGGTGGATCCACGATGTCAGGAGATCGATTGAGCTTAACAGCATAATTATTATTAG 7
51 sHC CTTCCAGTACCTGAGTCAGTCTGAGAAATCGAACTCCTGACCTCAGGCAGTCACCTTCTT 5
52 sHC TGTCTTGAGGCTTACTAGTGCACTCCCGTCGAATTATGTTTAAAGATGTAAATTATTATT 7
53 mHC GCTGAGAGTCAGGTGGACAGGACTCTCCTCGAAACTCTGCCTGTTTTTGCCTTTTACTTT 8
54 sHC TATTTGTAAATATTTTAGTATTTACAAATCGATTATGATAGTAGATTGTAGAAAAAAACA 8
55 sHC CCTTATAATTTAGTTAATGAAAATATAATCGAATAAAGTATTCAGAAGTAAGCCTGGAAA 9
56 sHC TTCCACTCTGGAAAACATATCACTTCTCTCGATACCTATATTAAGAAAGAAGAAAGGTCT X
57 sHC TTATCCATAACCATAAGATATTCTAAGATCGAATAGTGACACTTATGCAGAGGAGAGAAT 18
58 mHC TTTAGGAAGTTTTTTTATTATCATTTTTTCGAAACACCCGATTGTTTAAATTTTAATGAC 10
59 sHC CCTGTAAGATTCCATTTATACAACATTATCGAGCAATTCCACTATGGGTATATATCCAAA 10
60 sHC TCCTTGGATAGGACATTACATATCATTTTCGAGTAATATTAAAGATTCCAGGACTCACAA 12
61 sHC GTAGATATCCAAACATTTATGAAATTAATCGAGAACAAAAGGGCATAATGTATTATACGG 12
62 mHC TATGTATTTATATATGATTACCATTATGTCGAGATAGAGTATGTAATCATTTTATGATTT 12
63 mHC TTATATCAGTATCAAAATAAAACTTATTTCGATAAAAAATAATGAAACAAATGCTTTTGC 15
64 sHC TTTATTGATTTTTTACTATTTTTTTTTTTCGAAATTCATCAGTACTTTGTAAAATGGAAT 16
65 mHC TGAGGCGGGTCTTTATCTCCACAGTGCCTCGAGCAAAAGCTTACTTTTTCAGAAAAGAAA 2
66 mHC TTCTTGACTTTAATTAAAGTAGTTGTTCTCGAATGTGGAGCATCATTTGCATTTCTTTCT 20
67 sHC TAGTTAAAAGTGAAGAAAAGGAAACTTTTCGATGTACTTTTCCATTTGTTTACGTACATG 3
68 mHC TCTTTACTAAAGAGAATCTATCTTGTATTCGAATAAGATTATCTCCTTTATACATCTATT 4
69 mHC TGGCTGAATTAATTTTTTTAAACATGATTCGATCTAGAAATTCACAGGAAAATTTCTTGA 6
70 mHC TATTCATATAAGGAAAGAAAGAAAAATCTCGATCCATTTTTCCTTTCTTTATGTAACTGG 6
71 sHC CCTTATTTAAAAAGAAATATTAGGAATTTCGACACTATTATCTAAAGTATATTCCATACT 7
72 sHC ATGGTAAATGACTTGTATTTATTAGATATCGATTAGAACAGGAATCCTGTTTATGTTAAT 8
73 sHC TCTCTAAAAACAGAAATATCTTACTTTTTCGAAAAAGATATATAAAGCAATAATTAACAG X
74 mHC TTTATTTTATTTTTATTATTTGAAATTCTCGAGAAGTTCTCTATATCCTAATTCCCCTCT 10
75 mHC AAGCATATATATATATATTGAATAAGTGTCGATATAGACAATATGAAAACAGACTATATA 4
76 mHC GAGGCGGGTGATTCACAAGGTCAGATGTTCGATAATTCTGGATTTGAGCTTGTTACAGAT 6
77 mHC ATGCTAAATTATGTAAAATGGAATATGTTCGATTCTTATCAATTGAAGATTGAAAAGGTG 5
78 mHC AATGTAAAATATCACTAATATTTCTCTATCGATATGTAACATTGAACAGTTCCAAATGAG 9
79 sHC ACTTCATTTTTTTATTTGAGATAGAGTCTCGACAGAACCTATACATATAACAGTGCATCT X
80 mHC TTTAATGAATATTAAATAACAACAAATATCGAAGCATCCTGTAGTCTAAAAATAAACACT 5
81 mHC ATTTTTAATTTAATATTTGTTTTGTCTCTCGAAAACAGTGATTTTTGTAAAGGAAATATT 6
82 mHC TTTACTATTGAATAACTAATCAAATTCATCGAATATATCTATTACTCGCTGTACTAAAGG 2
83 mHC ATGAATTAAAAATATTCTTCAAATCTTATCGAACAGCTTATTTTTTCCTTGTATGACATA 5
84 sHC TTCTCATGTTTCTTTTTCTGACTAAATGTCGAATTAGTCTCTATTCTAGCTTTACTTGAG 3
85 mHC AATTCAGACCCCTGGTACTCAGGGGTCTTCGACAGCTGAGAGCAGTATTTAAAAATTTCT 1
86 mHC ATTATATATTCTAACTTGGAATTTTATTTCGACTGTATAATAAAACAGGACTTTTAGCAA 1
87 sHC GAAGCAGGCAGATCATGAGGTCAGAAGATCGATGGATGAATGGATAAACAAGATGTAGTG 12
88 mHC TTTTTCATCTATATTTATTCTACATAAATCGAATTCATCTATTTTCCACCATTATCTATC 12
89 mHC AATCCAGTTTTTGGTTTTGTTAGTAATCTCGATTATATAAATCCTAGCTAGCAGATAAAC 13
90 sHC AGTGTAGGAATGAAAACAAAAAGTAATGTCGAGTCATTAATTCTTGCTTCTTAACTGCTT 2
91 mHC TCATAATGAGTAACAATGTATAAAAATATCGAAACCCTGCTTTATTTTATTTATTTTTTT 20
92 mHC TATTTTACAATAATCTTCTTAAGTAATGTCGAGTAAAATTTATGTTCCATGAAAAAAATC 4
93 sHC TTCATGAGTCATAGTCAATTATATAATCTCGATTACTCAGAGCTGTAAAATACCTTGGCT 6
94 sHC TGTCTTGAGGCTTACTAGTGCACTCCCGTCGATCAGAAGATATAAATCTGGGCCGAAGTA 7
95 mHC TAAGATTATAGAAGTTACAGTGCATACTTCGAACCCTTTTGTTTATAAGTATATTTGAGA 8
96 sHC TCTACTTGTGCACATAATTTAAATCATATCGAAGGAAAAAATTGATATACAGAATGAAGC 2
97 sHC GTCAGGCAGATCACTCTAGGTCAGGAGTTCGATGTCCCTGTCAGACCAGGACACGTGGGC 19
98 mHC ATTCTGAAGAATTATATAACCTGATATATCGATTCCCTTTCTTTCTTTATTCCATTAGTC 5
99 sHC AAGGCGGGTAGATCATGAGATCAAGAGATCGAATTTCTGAGCTCCAGCAATCCACCCATC 10
100 sHC TAACTTTTGTCCATGAATATATATACTTTCGATGATGTTCTATTAAGAACAGTGAAAGGG 14
101 mHC ATTGTTTAAGCCAGCCAGCCTATGGTATTCGATGTAGGTTCATCAATTGTAACAAATGTA 17
102 sHC GAGGCGGGTGATTCACAAGGTCAGATGTTCGAAGTAATATTTTAATTATTTAATAGTTTA 6
103 mHC TTAAAAAAGATTTAAAAAGTCAAAAGAGTCGAAGTTATTAAATTTCCATCTAAAATTCCA 6
104 mHC ATATGTAGATATATGTTTTCAAGCAATATCGAAAAATGACTTCAAAGTCATGGATTTCAC 14
105 mHC GTATCACCCCTGGCCATTACATTATCCATCGAACCAACTTCAAATAAGGCAAACACCAAG 1
106 mHC CCTTTCAAATTTAGATTTAAAATCTATTTCGAAGTGCTTCTTTTGCTCTTCAATGATTAA 1
107 mHC AACAATAGTGAACATGTATTGTTTATATTCGATTACTCTTCCAAGAAGCTTAGTTGTAAC 18
108 sHC CTATATTTATCTGTCCACATCAGTGTTATCGAACTCCTGACGTCAGGTGATCTACCTGCC 3
109 sHC GGCAGGTAGATCACCTGACGTCAGGAGTTCGATGTACTTTTCCATTTGTTTACGTACATG 3
110 mHC AACTCTGTATTTTCTTTTGTAAGATTCATCGAACATTCAAATTCCCTAAAGAAAAGAGAG 4
111 sHC TATTTTACAATAATCTTCTTAAGTAATGTCGAGTAAAATTTATGTTCCATGAAAAAAATC 4
112 sHC AGGAAATTATAATATTGTGATTAAAAGTTCGAAGAGTTAACTGTAACTTTGAGAAGTTAA 8
113 mHC CCTTATAATTTAGTTAATGAAAATATAATCGAAATGAATTACCCAAAGGGAAAATAAATG 9
114 sHC ATGCAGATATTTTTCAACCAAACGAGGATCGAGGCCGCAGTAAGCTGTGTTCACACCACT 9
115 sHC GACAGGTGGATCATCTAATGTCAGGAGTTCGATTTGCTATTTGGAGAGCAATGAAACTGA X
116 sHC GACAGGTGGATCATCTAATGTCAGGAGTTCGACCCATCAGATGTTACTGAGGAAACACAG X
117 sHC AGGTGGGTGGATCCACGATGTCAGGAGATCGATCTGGATACACCTGGAAAGACCGTTATT 7
118 mHC CATTTAATAGATACTCAGTAAATGTTTGTCGATCTGTTAGTAAACAGTGTCTAGTAGTCA 14
119 mHC TATATACATATTTTTAAGAAAAACAGTATCGATGAAGCAATATTCTTCCATCTTCAATTT 2
120 sHC AGATTACTCAAAAATTTTTTTAGAATTCTCGATTCTTATATGATATACATCTCTCCTGGA 2
表4.a5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
1 58854203 58854234 58918114 58918145 1 58850233 58854234 58918114 58922115
2 114879815 114879846 114930122 114930153 10 114879815 114883816 114930122 114934123
3 109687914 109687945 109761674 109761705 12 109687914 109691915 109761674 109765675
4 64426803 64426834 64462354 64462385 14 64426803 64430804 64462354 64466355
5 23216838 23216869 23283304 23283335 16 23216838 23220839 23279334 23283335
6 26843104 26843135 26900262 26900293 2 26839134 26843135 26900262 26904263
7 17392864 17392895 17435717 17435748 21 17388894 17392895 17431747 17435748
8 17392864 17392895 17439402 17439433 21 17388894 17392895 17435432 17439433
9 17393292 17393323 17441050 17441081 21 17393292 17397293 17441050 17445051
10 56140829 56140860 56168655 56168686 5 56136859 56140860 56168655 56172656
11 56140829 56140860 56182062 56182093 5 56136859 56140860 56178092 56182093
12 56140829 56140860 56232409 56232440 5 56136859 56140860 56228439 56232440
13 28430371 28430402 28471461 28471492 8 28426401 28430402 28471461 28475462
14 110141802 110141833 110164010 110164041 1 110141802 110145803 110160040 110164041
15 110164010 110164041 110260665 110260696 1 110160040 110164041 110256695 110260696
16 121570719 121570750 121596903 121596934 10 121566749 121570750 121592933 121596934
17 127007 127038 183730 183761 10 127007 131008 179760 183761
18 98957049 98957080 99022282 99022313 11 98953079 98957080 99018312 99022313
19 91096267 91096298 91165754 91165785 15 91096267 91100268 91161784 91165785
20 27288253 27288284 27358113 27358144 16 27284283 27288284 27358113 27362114
21 107626100 107626131 107703592 107703623 3 107626100 107630101 107703592 107707593
22 120821865 120821896 120858831 120858862 3 120817895 120821896 120858831 120862832
23 37845589 37845620 37862832 37862863 4 37845589 37849590 37862832 37866833
24 130766459 130766490 130793708 130793739 X 130762489 130766490 130793708 130797709
25 68921047 68921078 68947630 68947661 X 68917077 68921078 68943660 68947661
26 54591576 54591607 54654414 54654445 12 54587606 54591607 54654414 54658415
27 64426803 64426834 64462354 64462385 14 64426803 64430804 64462354 64466355
28 151449133 151449164 151566571 151566602 6 151445163 151449164 151562601 151566602
29 85660887 85660918 85682353 85682384 3 85660887 85664888 85682353 85686354
30 97699356 97699387 97751925 97751956 15 97695386 97699387 97751925 97755926
31 15159367 15159398 15200610 15200641 16 15155397 15159398 15200610 15204611
32 89728565 89728596 89805232 89805263 9 89728565 89732566 89805232 89809233
33 82035912 82035943 82086732 82086763 6 82035912 82039913 82086732 82090733
34 11765160 11765191 11857514 11857545 8 11761190 11765191 11857514 11861515
35 14257097 14257128 14333977 14334008 10 14253127 14257128 14330007 14334008
36 26047414 26047445 26074632 26074663 15 26043444 26047445 26070662 26074663
37 11954547 11954578 11996894 11996925 16 11950577 11954578 11996894 12000895
38 27236516 27236547 27288253 27288284 16 27236516 27240517 27284283 27288284
39 48817066 48817097 48918494 48918525 19 48817066 48821067 48918494 48922495
40 20006512 20006543 20078974 20079005 20 20002542 20006543 20078974 20082975
41 21487530 21487561 21499599 21499630 20 21483560 21487561 21495629 21499630
42 166286147 166286178 166311616 166311647 4 166282177 166286178 166311616 166315617
43 37845589 37845620 37859966 37859997 4 37845589 37849590 37859966 37863967
44 115875719 115875750 115945548 115945579 X 115875719 115879720 115941578 115945579
45 48539737 48539768 48618802 48618833 1 48535767 48539768 48618802 48622803
46 48539737 48539768 48625938 48625969 1 48535767 48539768 48621968 48625969
47 6219982 6220013 6302811 6302842 X 6219982 6223983 6298841 6302842
48 35163743 35163774 35189737 35189768 17 35163743 35167744 35185767 35189768
49 29891288 29891319 29934336 29934367 21 29891288 29895289 29934336 29938337
50 36953187 36953218 36976432 36976463 7 36953187 36957188 36976432 36980433
51 56056790 56056821 56069488 56069519 5 56056790 56060791 56069488 56073489
52 22396847 22396878 22494715 22494746 7 22392877 22396878 22494715 22498716
53 122799764 122799795 122834548 122834579 8 122799764 122803765 122834548 122838549
54 13602479 13602510 13632064 13632095 8 13602479 13606480 13632064 13636065
55 114547520 114547551 114640305 114640336 9 114547520 114551521 114636335 114640336
56 129690691 129690722 129712806 129712837 X 129686721 129690722 129712806 129716807
57 58181079 58181110 58205063 58205094 18 58181079 58185080 58201093 58205094
58 3728370 3728401 3766614 3766645 10 3728370 3732371 3766614 3770615
59 86379474 86379505 86449156 86449187 10 86379474 86383475 86445186 86449187
60 10186674 10186705 10224399 10224430 12 10186674 10190675 10220429 10224430
61 82971707 82971738 83013222 83013253 12 82971707 82975708 83009252 83013253
62 83942863 83942894 83954032 83954063 12 83938893 83942894 83954032 83958033
63 91096267 91096298 91157513 91157544 15 91096267 91100268 91157513 91161514
64 10002949 10002980 10049364 10049395 16 10002949 10006950 10045394 10049395
65 79971406 79971437 79981700 79981731 2 79967436 79971437 79981700 79985701
66 10252796 10252827 10337815 10337846 20 10248826 10252827 10333845 10337846
67 159122585 159122616 159171258 159171289 3 159122585 159126586 159171258 159175259
68 125303537 125303568 125344175 125344206 4 125299567 125303568 125344175 125348176
69 41262229 41262260 41314380 41314411 6 41258259 41262260 41310410 41314411
70 5723608 5723639 5777459 5777490 6 5723608 5727609 5773489 5777490
71 69585104 69585135 69650595 69650626 7 69585104 69589105 69646625 69650626
72 93946017 93946048 93987890 93987921 8 93942047 93946048 93983920 93987921
73 118654955 118654986 118719838 118719869 X 118654955 118658956 118719838 118723839
74 62722126 62722157 62762850 62762881 10 62722126 62726127 62762850 62766851
75 114660322 114660353 114716510 114716541 4 114660322 114664323 114712540 114716541
76 151449133 151449164 151468540 151468571 6 151445163 151449164 151468540 151472541
77 42385888 42385919 42426661 42426692 5 42381918 42385919 42422691 42426692
78 125047796 125047827 125098545 125098576 9 125043826 125047827 125094575 125098576
79 44203586 44203617 44239491 44239522 X 44199616 44203617 44235521 44239522
80 141308791 141308822 141343213 141343244 5 141308791 141312792 141339243 141343244
81 28494470 28494501 28536924 28536955 6 28490500 28494501 28536924 28540925
82 68188547 68188578 68261564 68261595 2 68188547 68192548 68257594 68261595
83 162107624 162107655 162154110 162154141 5 162107624 162111625 162154110 162158111
84 63282250 63282281 63329745 63329776 3 63278280 63282281 63325775 63329776
85 203216286 203216317 203265130 203265161 1 203216286 203220287 203265130 203269131
86 208035294 208035325 208092230 208092261 1 208031324 208035325 208092230 208096231
87 123047865 123047896 123114063 123114094 12 123043895 123047896 123110093 123114094
88 22550236 22550267 22591468 22591499 12 22550236 22554237 22587498 22591499
89 52988952 52988983 53036652 53036683 13 52984982 52988983 53032682 53036683
90 11504797 11504828 11532162 11532193 2 11504797 11508798 11532162 11536163
91 38210518 38210549 38329699 38329730 20 38210518 38214519 38329699 38333700
92 187960515 187960546 188019077 188019108 4 187956545 187960546 188015107 188019108
93 154259046 154259077 154298459 154298490 6 154259046 154263047 154294489 154298490
94 22365643 22365674 22396847 22396878 7 22365643 22369644 22392877 22396878
95 52230322 52230353 52253135 52253166 8 52230322 52234323 52249165 52253166
96 77486960 77486991 77514867 77514898 2 77482990 77486991 77514867 77518868
97 9846242 9846273 9871036 9871067 19 9846242 9850243 9867066 9871067
98 17887397 17887428 17964289 17964320 5 17887397 17891398 17964289 17968290
99 30527367 30527398 30585089 30585120 10 30527367 30531368 30585089 30589090
100 68255587 68255618 68325745 68325776 14 68255587 68259588 68325745 68329746
101 35289043 35289074 35315930 35315961 17 35285073 35289074 35311960 35315961
102 151387953 151387984 151449133 151449164 6 151387953 151391954 151445163 151449164
103 169187906 169187937 169230654 169230685 6 169183936 169187937 169230654 169234655
104 51892245 51892276 51939308 51939339 14 51888275 51892276 51935338 51939339
105 110164010 110164041 110187380 110187411 1 110160040 110164041 110183410 110187411
106 76048774 76048805 76098903 76098934 1 76048774 76052775 76094933 76098934
107 23965423 23965454 24007739 24007770 18 23965423 23969424 24003769 24007770
108 159142637 159142668 159171227 159171258 3 159142637 159146638 159167257 159171258
109 159142637 159142668 159171258 159171289 3 159142637 159146638 159171258 159175259
110 152218333 152218364 152243834 152243865 4 152214363 152218364 152243834 152247835
111 187960515 187960546 188019077 188019108 4 187956545 187960546 188015107 188019108
112 65608206 65608237 65633322 65633353 8 65604236 65608237 65633322 65637323
113 114559604 114559635 114640305 114640336 9 114559604 114563605 114636335 114640336
114 33275144 33275175 33317596 33317627 9 33271174 33275175 33317596 33321597
115 40499056 40499087 40520869 40520900 X 40495086 40499087 40520869 40524870
116 40499056 40499087 40522127 40522158 X 40495086 40499087 40518157 40522158
117 36953187 36953218 36980351 36980382 7 36953187 36957188 36980351 36984352
118 91001527 91001558 91060989 91061020 14 91001527 91005528 91060989 91064990
119 167702360 167702391 167773293 167773324 2 167702360 167706361 167769323 167773324
120 44766242 44766273 44792801 44792832 2 44766242 44770243 44788831 44792832
表4.a6
   探針 PCR- 引子 1_ID PCR_ 引子 1
1 ORF1_1_58851578_58854234_58918114_58921170_FR OBD159_2229 ATCAGGCGTGCTTGTGAGGTTGTGC
2 ORF1_10_114879815_114883799_114930122_114938828_RR OBD159_2233 GAAAATCCCTTGAGCCTCGGAGC
3 ORF1_12_109687914_109689169_109761674_109764027_RR OBD159_2237 CCCAGCACTTTGGTAATCCCAGC
4 ORF1_14_64426803_64429125_64462354_64463999_RR OBD159_2241 ACTTTATCTTGTAGAGACACGGCTAT
5 ORF1_16_23216838_23220910_23281989_23283335_RF OBD159_2245 GGTGAAACCCCATCTCTACCAAA
6 ORF1_2_26839991_26843135_26900262_26907333_FR OBD159_2249 GCTCAGTAAAGCCCTGTGTTGTGGAA
7 ORF1_21_17391129_17392895_17434190_17435748_FF OBD159_2253 CGCCTGTAATCCCACCACTTTGG
8 ORF1_21_17391129_17392895_17437778_17439433_FF OBD159_2257 CGCCTGTAATCCCACCACTTTGG
9 ORF1_21_17393292_17394472_17441050_17442330_RR OBD159_2261 TACCAGGGCTGAGGGTGTTGTCCTAT
10 ORF1_5_56137297_56140860_56168655_56170386_FR OBD159_2265 TGTATGTGTGGCTGGGCGTAGTG
11 ORF1_5_56137297_56140860_56180306_56182093_FF OBD159_2269 TGCCAGTAATCCCAGAACTTTGG
12 ORF1_5_56137297_56140860_56230314_56232440_FF OBD159_2273 TGTATGTGTGGCTGGGCGTAGTGGTT
13 ORF1_8_28429398_28430402_28471461_28475878_FR OBD159_2277 TCCAAAGTGCTGGGATTACAGGC
14 ORF10_1_110141802_110145853_110155952_110164041_RF OBD159_2281 GCATAAAAGAGCCACCTGCCAGC
15 ORF10_1_110155952_110164041_110258457_110260696_FF OBD159_2285 TCCAGCATAAAAGAGCCACCTGCCAG
16 ORF10_10_121564423_121570750_121595209_121596934_FF OBD159_2289 GGAGAAGGTTCCAGAAGCCGCCT
17 ORF10_10_127007_130384_175918_183761_RF OBD159_2293 TTCCCATCCTCTGCTATTTGGTTACC
18 ORF10_11_98953280_98957080_99019353_99022313_FF OBD159_2297 GAACTACTTCACGGGAGAGATTACTC
19 ORF10_15_91096267_91099737_91157513_91165785_RF OBD159_2301 ATTGTCTTCCATTTTCTTCTGCTTA
20 ORF10_16_27283060_27288284_27358113_27360574_FR OBD159_2305 GGCATTCTGAGGGCAAGAGGTGTG
21 ORF10_3_107626100_107637571_107703592_107708851_RR OBD159_2309 TTTTGTCATTATTTGGTCATTTCAC
22 ORF10_3_120814252_120821896_120858831_120873172_FR OBD159_2313 GCTAACAGGACACACCCAGTGCC
23 ORF10_4_37845589_37847420_37862832_37864637_RR OBD159_2317 TGCCACAGCAAGTCTATCAGCATCCG
24 ORF10_X_130763205_130766490_130793708_130805512_FR OBD159_2321 ACTTGTCTTTTCTCATTCTCTAACA
25 ORF10_X_68908108_68921078_68942609_68947661_FF OBD159_2325 TAGCCTGTTCCTGCCCCTCTCTG
26 ORF100_12_54589309_54591607_54654414_54660876_FR OBD159_2329 TAACCCTCACAACCACCCAGGAG
27 ORF101_14_64426803_64429125_64462354_64463999_RR OBD159_2241 ACTTTATCTTGTAGAGACACGGCTAT
28 ORF104_6_151443530_151449164_151559030_151566602_FF OBD159_2333 CGCCTGTAACCCCAGCATTTTGG
29 ORF105_3_85660887_85666710_85682353_85685845_RR OBD159_2337 GAATAACCCAAGTTCACAGCAATGGT
30 ORF106_15_97695238_97699387_97751925_97755483_FR OBD159_2341 CAACTGACATCTTTCAACTCTGGGAG
31 ORF106_16_15155840_15159398_15200610_15205140_FR OBD159_2345 GAGAGCGTTGGGCTTTGTCCAGC
32 ORF107_9_89728565_89736522_89805232_89809003_RR OBD159_2349 CTATTCACCTTGACTTTGGCAGCACT
33 ORF109_6_82035912_82039349_82086732_82090252_RR OBD159_2353 CACTAAGGGTCTGTCACTGAAAGGCT
34 ORF109_8_11762928_11765191_11857514_11859558_FR OBD159_2357 CTGGGCAACAGTGCGAGACTCTG
35 ORF11_10_14255629_14257128_14331424_14334008_FF OBD159_2361 AGTGGCTCACACCTGTAATCCCG
36 ORF11_15_26044519_26047445_26072122_26074663_FF OBD159_2365 TAATACCAGCACTTTGGGAGGCT
37 ORF11_16_11953475_11954578_11996894_11999391_FR OBD159_2369 AGCCTGGGTGACAGAGTAAGACT
38 ORF11_16_27236516_27245702_27283060_27288284_RF OBD159_2373 ATTCTGAGGGCAAGAGGTGTGAGA
39 ORF11_19_48817066_48819208_48918494_48922385_RR OBD159_2377 AGCCTGGGCAACAGAGTGAGACT
40 ORF11_20_20005082_20006543_20078974_20082009_FR OBD159_2381 CAGGCACCACACCACAAGCACTG
41 ORF11_20_21483562_21487561_21497814_21499630_FF OBD159_2385 AAGAAGGCTGGGTGTCCAAGCAG
42 ORF11_4_166285010_166286178_166311616_166318662_FR OBD159_2389 CGTGCCCAGCCAAGATGACTTTT
43 ORF11_4_37845589_37847420_37859966_37862832_RR OBD159_2393 TCTGCCACAGCAAGTCTATCAGCATC
44 ORF11_X_115875719_115878414_115936015_115945579_RF OBD159_2397 CAGGAATCATTTGACACAATCCCC
45 ORF110_1_48532003_48539768_48618802_48625969_FR OBD159_2401 AAAGGTTCTTGCCACATTCCGCCCCA
46 ORF111_1_48532003_48539768_48618802_48625969_FF OBD159_2405 TTCTTGCCACATTCCGCCCCAGC
47 ORF112_X_6219982_6227001_6295729_6302842_RF OBD159_2409 GAGTTGGCAGGGAAATGGACAAGGTC
48 ORF113_17_35163743_35164806_35182581_35189768_RF OBD159_2413 AAGCCTTCCCACAAAGAAAACTCAGG
49 ORF114_21_29891288_29892971_29934336_29938623_RR OBD159_2417 CTTGGCTGCCTTCCTACACAGGGTAT
50 ORF115_7_36953187_36955186_36976432_36980351_RR OBD159_2421 GTCAAGAGAGGCACGGTGGCTCA
51 ORF117_5_56056790_56059051_56069488_56074299_RR OBD159_2425 GCGAGTTTGCCTGGTGGTCTCTC
52 ORF117_7_22390272_22396878_22494715_22499120_FR OBD159_2429 AGGCTCCTGGGTTCCTATGTTCAAAT
53 ORF117_8_122799764_122802282_122834548_122836477_RR OBD159_2433 CTCCTACAAAGCAAAGGCTGAGG
54 ORF117_8_13602479_13607345_13632064_13635521_RR OBD159_2437 ATACAGCCACTTCAACTTGTCCTAAT
55 ORF118_9_114547520_114550346_114637124_114640336_RF OBD159_2441 AGAAGAGATTGATAAGGTTGTGTA
56 ORF118_X_129688045_129690722_129712806_129719890_FR OBD159_2445 CAGAATAAATGTGTCCCAGATGACG
57 ORF119_18_58181079_58183629_58202022_58205094_RF OBD159_2449 TCCAGTAGTCTGTGAGCATCTCCAT
58 ORF12_10_3728370_3731203_3766614_3768148_RR OBD159_2453 CCCTTATTCATTCATCCAGAAAACCA
59 ORF12_10_86379474_86383560_86442251_86449187_RF OBD159_2457 ATAAATAGGTAAGAAAAGAACAGC
60 ORF12_12_10186674_10187896_10218366_10224430_RF OBD159_2461 GCTGTGTCTCTCCCAGGTAGGCT
61 ORF12_12_82971707_82974166_83009437_83013253_RF OBD159_2465 GTTTTGCTGTAGTTTTGCTGAAGTTC
62 ORF12_12_83941063_83942894_83954032_83957600_FR OBD159_2469 ACATATATTAATATAATAAT
63 ORF12_15_91096267_91099737_91157513_91165785_RR OBD159_2473 AACACCTTAGCAATACTGTCCCC
64 ORF12_16_10002949_10008026_10047306_10049395_RF OBD159_2477 CTCAAGTTGTCACAGCATTACCACCT
65 ORF12_2_79968604_79971437_79981700_79985274_FR OBD159_2481 CTATTTCCTCCCCTCACCTTCCACTC
66 ORF12_20_10249014_10252827_10332102_10337846_FF OBD159_2485 CCCCAGGCAGTCCTATTAGAAAATGT
67 ORF12_3_159122585_159126737_159171258_159178334_RR OBD159_2489 GCCACCCAAAGACTGTAAGACAAATC
68 ORF12_4_125301039_125303568_125344175_125348116_FR OBD159_2493 GTGTGTGTGTTCACTATTTCTGACTC
69 ORF12_6_41251004_41262260_41306014_41314411_FF OBD159_2497 ATGAGAGAAACAAAACCCCACATA
70 ORF12_6_5723608_5725733_5763384_5777490_RF OBD159_2501 CAAATGGTGGTGGAGCAACGGGT
71 ORF12_7_69585104_69587963_69646882_69650626_RF OBD159_2505 CATCTCTCACTACCAGGACCAGC
72 ORF12_8_93942397_93946048_93985677_93987921_FF OBD159_2509 GCCCTCTTAGATTGATGCCAGAAGTA
73 ORF12_X_118654955_118657669_118719838_118725132_RR OBD159_2513 CAGAAGGGACAACAAACAATCCAGTC
74 ORF121_10_62722126_62724612_62762850_62765655_RR OBD159_2517 AGTCCAGACCTTGCCACAACCCC
75 ORF121_4_114660322_114662941_114712388_114716541_RF OBD159_2521 TGCCTCACACAGAGTAGACAATACAT
76 ORF123_6_151443530_151449164_151468540_151471174_FR OBD159_2525 CGCCTGTAACCCCAGCATTTTGG
77 ORF124_5_42377041_42385919_42424469_42426692_FF OBD159_2529 GGCAAAACAACTTCCCACTGACCTGT
78 ORF124_9_125044256_125047827_125094721_125098576_FF OBD159_2533 ATCTGAACTGAAATGTATGTAAGTA
79 ORF124_X_44196000_44203617_44233955_44239522_FF OBD159_2537 GGTCGTGAGCCCTTGAGAGTGAC
80 ORF125_5_141308791_141312972_141341365_141343244_RF OBD159_2541 TCCTGGGAAAGCGTTTGCTAACATTA
81 ORF125_6_28490451_28494501_28536924_28541272_FR OBD159_2545 TGTAGATGACTCTCTTTGTCCCCTCA
82 ORF126_2_68188547_68193452_68260319_68261595_RF OBD159_2549 GGGAGAAAATACAACATACAGATGAC
83 ORF126_5_162107624_162113021_162154110_162157909_RR OBD159_2553 CTCTGAGTGTTCACGCCTGGCTC
84 ORF128_3_63280859_63282281_63322701_63329776_FF OBD159_2557 CTATTTTCACATCATCTTGTAAGTT
85 ORF13_1_203216286_203223882_203265130_203266595_RR OBD159_2561 GCGAGCAGCCACTCAGCATTACACTA
86 ORF13_1_208028237_208035325_208092230_208093532_FR OBD159_2565 GCCAGGTATGTCAGGCTCCAGAG
87 ORF13_12_123039105_123047896_123111911_123114094_FF OBD159_2569 GGCTCACGCCTGTAATCCCAGTA
88 ORF13_12_22550236_22564251_22589587_22591499_RF OBD159_2573 GGGCAGAAGATGGAAAAGAACAAGTG
89 ORF13_13_52983399_52988983_53034265_53036683_FF OBD159_2577 TTTTCTTGTTCAATACTGCTACTAC
90 ORF13_2_11504797_11509096_11532162_11535545_RR OBD159_2581 GTGTCTGGCACAAGAAAGGGCTC
91 ORF13_20_38210518_38212890_38329699_38336059_RR OBD159_2585 CCAACAATCTCTCCCCTCACTGC
92 ORF13_4_187957960_187960546_188016179_188019108_FF OBD159_2589 AGAAAGAGGAGGGTGGGATTTTAGGG
93 ORF13_6_154259046_154260916_154294994_154298490_RF OBD159_2593 GTAACGATTTCCCAAGTGGTCCCCAA
94 ORF13_7_22365643_22368712_22390272_22396878_RF OBD159_2597 AGGCTCCTGGGTTCCTATGTTCAAAT
95 ORF13_8_52230322_52233827_52248401_52253166_RF OBD159_2601 GGCATACAAGTAGGATACCAAGCAGA
96 ORF130_2_77483560_77486991_77514867_77519288_FR OBD159_2605 TCCCATTTCCAACTCTTCTGATAAA
97 ORF131_19_9846242_9849549_9869701_9871067_RF OBD159_2609 TGCCTGTAATCCCAGCACTTTGG
98 ORF132_5_17887397_17895130_17964289_17970189_RR OBD159_2613 ACCCAAACCTTCCTTTCTCCACAGAG
99 ORF133_10_30527367_30529631_30585089_30589121_RR OBD159_2617 CACCTGTAATCCCAGCACTTTGG
100 ORF134_14_68255587_68260022_68325745_68327713_RR OBD159_2621 AATCCATCTGCCTCATTTCCCTCCCC
101 ORF138_17_35287155_35289074_35314277_35315961_FF OBD159_2625 CCATCTACTAACCAGAAAGACAGCCC
102 ORF138_6_151387953_151393542_151443530_151449164_RF OBD159_2629 CGCCTGTAACCCCAGCATTTTGG
103 ORF138_6_169185535_169187937_169230654_169232256_FR OBD159_2633 ACACATCCACTGATAGGCAACAACTG
104 ORF139_14_51886119_51892276_51935246_51939339_FF OBD159_2637 GTTCCTCTTGCTCCACTTGTCAACAG
105 ORF14_1_110155952_110164041_110184326_110187411_FF OBD159_2641 GCATAAAAGAGCCACCTGCCAGC
106 ORF14_1_76048774_76050727_76086337_76098934_RF OBD159_2645 TTACTGGTGTCTTTTATGAACAAA
107 ORF14_18_23965423_23972468_24001102_24007770_RF OBD159_2649 GCCACCTCACCCAGACTATTTTA
108 ORF14_3_159142637_159144036_159166834_159171258_RF OBD159_2653 GCCAACATCTCTCTCTATCTAAATCT
109 ORF14_3_159142637_159144036_159171258_159178334_RR OBD159_2657 TCAGTGGGATGTGAGAAAGCCAATA
110 ORF14_4_152216416_152218364_152243834_152246201_FR OBD159_2661 CCCAGAAAGATGGATGAGTAGAAAAT
111 ORF14_4_187957960_187960546_188016179_188019108_FF OBD159_2589 AGAAAGAGGAGGGTGGGATTTTAGGG
112 ORF14_8_65603423_65608237_65633322_65635344_FR OBD159_2665 GCTGTTTGTTTTGTTTGGGAGAGTAA
113 ORF14_9_114559604_114561408_114637124_114640336_RF OBD159_2669 GAGAAGAGATTGATAAGGTTGTGT
114 ORF141_9_33273553_33275175_33317596_33319558_FR OBD159_2673 CAGTTTACCCTTGAACAGCAAATGC
115 ORF141_X_40497397_40499087_40520869_40522158_FR OBD159_2677 ATGAAGGAAGGGCTCTTGGCTGG
116 ORF142_X_40497397_40499087_40520869_40522158_FF OBD159_2681 ATGAAGGAAGGGCTCTTGGCTGG
117 ORF143_7_36953187_36955186_36980351_36983506_RR OBD159_2685 TGTCAAGAGAGGCACGGTGGCTCATA
118 ORF144_14_91001527_91004763_91060989_91062696_RR OBD159_2689 CGTGTCCAGGTATTTAGTGGCAGAAA
119 ORF144_2_167702360_167710563_167770932_167773324_RF OBD159_2693 TGAATGAATGAGTCTGTTGGAAAT
120 ORF144_2_44766242_44769058_44787731_44792832_RF OBD159_2697 CCTGGAAGTTTGAGGACAGTTTGGAC
表4.a7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
1 OBD159_2231 TCCTCTGAGACTGCTTTATGGTATCT OBD159_2229_2231 -0.001099989
2 OBD159_2235 CGTGTAACAGGGCAGCATCTGGG OBD159_2233_2235 -0.00318743
3 OBD159_2239 GGAAGGTTCTGAGCCGAGAGGAG OBD159_2237_2239 -0.004676628
4 OBD159_2243 TTGCTCAGGCTGGAATGCGGTGG OBD159_2241_2243 -0.003238968
5 OBD159_2247 CTTGAACAAATGGATGTGGCTGTGTA OBD159_2245_2247 -0.003973069
6 OBD159_2251 GAGCAAAAGAAGCCAATGCGAAGGTA OBD159_2249_2251 -0.001633598
7 OBD159_2255 GTCACTTGTGCTAAATGCCACTTC OBD159_2253_2255 -0.001854302
8 OBD159_2259 AAGGATTGCTTGAGCCCAGGAAT OBD159_2257_2259 -0.002930402
9 OBD159_2263 GGATACTAACTGTGCTACTTTGGAGC OBD159_2261_2263 -0.001071874
10 OBD159_2267 CAGTAGTCTCCCCTCACCCTGGA OBD159_2265_2267 -0.001226577
11 OBD159_2271 CATCGTCTTTGGTTTTGATAGTGAAG OBD159_2269_2271 -0.002857815
12 OBD159_2275 CCCGACATAAATACAGGCAACATCTA OBD159_2273_2275 -0.002621971
13 OBD159_2279 CCTTTCCCCAAACAAACTTATTCCTT OBD159_2277_2279 -0.003175304
14 OBD159_2283 CCCAAACTCCAAAGGCAGCGTGC OBD159_2281_2283 -0.004504979
15 OBD159_2287 GGCAAAAGCAATGAGAATCCAATCAG OBD159_2285_2287 -0.005705695
16 OBD159_2291 GCGTCCAATCAGAACTTGCGAGC OBD159_2289_2291 -0.003584401
17 OBD159_2295 GCTTGGGTCTGGAAAGGCAGGAC OBD159_2293_2295 -0.004126755
18 OBD159_2299 GACTGTGGAAATAAGGATGAAAGAAG OBD159_2297_2299 -0.001827365
19 OBD159_2303 TCTTGCCTATGTTTTGTTGTATCAT OBD159_2301_2303 -0.003492146
20 OBD159_2307 GCCTGCCTTGGTGAAACTGACCT OBD159_2305_2307 -0.00088252
21 OBD159_2311 GTAATACTCTCATTTTAGAAGCAA OBD159_2309_2311 -6.98E-05
22 OBD159_2315 ACCCACCCACACAGATACCCGTA OBD159_2313_2315 -0.000581864
23 OBD159_2319 GTTCCATCATAGCAGGATTGGGTCAT OBD159_2317_2319 -0.002578329
24 OBD159_2323 ATTTTGCTGTGTTTCCCAAGCCTTA OBD159_2321_2323 -0.000730176
25 OBD159_2327 GGACTCAGACTGCCTGGCTTTGA OBD159_2325_2327 -0.001214879
26 OBD159_2331 CCTTGGGAAGCCATACTCACCCC OBD159_2329_2331 -0.002869156
27 OBD159_2243 TTGCTCAGGCTGGAATGCGGTGG OBD159_2241_2243 -0.003119541
28 OBD159_2335 AAGATACACCAAGCACAAGTCCAAAT OBD159_2333_2335 -0.002373158
29 OBD159_2339 CTTCAGTTTGGAGCAACACCTTCACG OBD159_2337_2339 -0.003453509
30 OBD159_2343 TCGTGTGCTACCTGAACTCTGGGACA OBD159_2341_2343 -0.003945485
31 OBD159_2347 CGTTGGAAGAGATGGCTCCGATG OBD159_2345_2347 -0.001300019
32 OBD159_2351 GGCACCAAGTAGCCCACAGTATTACC OBD159_2349_2351 -0.002149682
33 OBD159_2355 GCCTACCAAACAGCCCTGAGAAAGAT OBD159_2353_2355 -0.003025162
34 OBD159_2359 GCCACCACAGTAACCAAAGAAATCT OBD159_2357_2359 -0.003509337
35 OBD159_2363 GGGCATTCATAGTTGCTTTGTTTGTA OBD159_2361_2363 -0.000950471
36 OBD159_2367 CACCTGTAATCCCAGCACTTTGG OBD159_2365_2367 -0.000179472
37 OBD159_2371 GAGACACACAATAAAACAACTGACTC OBD159_2369_2371 -0.000469302
38 OBD159_2375 GTGAAAACAATAATACATACTCTTG OBD159_2373_2375 -0.00153782
39 OBD159_2379 GGACAGGTAACTACGGGTCTCCC OBD159_2377_2379 -0.003874148
40 OBD159_2383 CCCCTTCCTCTCACCCAAAGTTC OBD159_2381_2383 -0.003036388
41 OBD159_2387 TGGGCTGAGGTTCCACAGAGCAG OBD159_2385_2387 -0.000105726
42 OBD159_2391 CTCTAAGCCAAGTGCTAATGAGC OBD159_2389_2391 -0.001625396
43 OBD159_2395 GAAAATAACAGTTCTCAGGAAGGCAT OBD159_2393_2395 -0.002782935
44 OBD159_2399 CTCCACTTCTACCACCACGAGTA OBD159_2397_2399 -0.001994291
45 OBD159_2403 ATTTATTCCATTACCTTGGGCACCCC OBD159_2401_2403 -0.003045347
46 OBD159_2407 CTACCCTGCTTTCTGCTGGAGTC OBD159_2405_2407 -0.003570374
47 OBD159_2411 GAGGCTGTTTCCACTACCACATAAAA OBD159_2409_2411 -0.003053494
48 OBD159_2415 AAGATTCCTGCTGGGCTCCATCCTCA OBD159_2413_2415 -0.00492995
49 OBD159_2419 ACATAAAAGGGAGTGCCTGACTAACG OBD159_2417_2419 -0.000432397
50 OBD159_2423 ACCATAAGTGGGTCCCTGTCACG OBD159_2421_2423 -0.002489477
51 OBD159_2427 TCCTTTCCTGAGAGAGTAGGGATA OBD159_2425_2427 -0.000208789
52 OBD159_2431 GGAAAGCAGAAAAGACATCACAAACC OBD159_2429_2431 -0.00046753
53 OBD159_2435 AAACCCCACAATGAGACCTTCTAAAT OBD159_2433_2435 -0.003120321
54 OBD159_2439 GAGCCAGGCACTTGGATTAGCAAAAT OBD159_2437_2439 -0.002487223
55 OBD159_2443 AAATGTGACTCTAAAGTTATCCTGC OBD159_2441_2443 -0.004687281
56 OBD159_2447 AGCCCACACTCCCGTTTTCTGTA OBD159_2445_2447 -0.001742961
57 OBD159_2451 TAACAGAAAAGAAAGAAATAAAGGG OBD159_2449_2451 -0.002597941
58 OBD159_2455 TGGGAAAGAAAGGACCTGTGAGTGTC OBD159_2453_2455 -0.001962092
59 OBD159_2459 TGATGAACGCCTGGGTTTCTTCCA OBD159_2457_2459 -0.003183439
60 OBD159_2463 GCACCATCAGGCTTCTGGGAATG OBD159_2461_2463 -0.006236142
61 OBD159_2467 TATGTCTGCTGCCTCTGTGCTGTC OBD159_2465_2467 -0.001347005
62 OBD159_2471 TTGTATTTAAAAATAGTTCTTT OBD159_2469_2471 -0.002022685
63 OBD159_2475 CTCTAAAACAGGGATGATAATGGCAT OBD159_2473_2475 -0.002663999
64 OBD159_2479 GTTTCTGCTCTTCATCTGGACAGGGC OBD159_2477_2479 -0.00204052
65 OBD159_2483 TGGGCAAGTTTGACTGGACATTTTCT OBD159_2481_2483 -0.001107302
66 OBD159_2487 TAGGGCTGCGTGGTGTTCCATTGTGT OBD159_2485_2487 -0.00507451
67 OBD159_2491 CAGTGTCTCTGACGCACAAATGCCTA OBD159_2489_2491 1.50E-05
68 OBD159_2495 GCCTCTGGCTGTAATGGATAATCTCC OBD159_2493_2495 -0.003767198
69 OBD159_2499 GAAAGACAGAACATAGAAAACAGAG OBD159_2497_2499 -0.006879732
70 OBD159_2503 CAACAACCTTTTCCTCACACGCAAA OBD159_2501_2503 -0.005202838
71 OBD159_2507 GCATTATTGGGACACATTATTAGGAC OBD159_2505_2507 -0.001497082
72 OBD159_2511 TCCAGAGGAGAGGAAGTGCCACAT OBD159_2509_2511 -0.003312559
73 OBD159_2515 GTCAAGTTTGTGGATTGTGTTGGTCA OBD159_2513_2515 -0.003444197
74 OBD159_2519 GCACGCTCCTGGTGAGATAAGCA OBD159_2517_2519 -0.000834834
75 OBD159_2523 CACCACCAGAAAACCAGAAAGCACCC OBD159_2521_2523 -0.003566778
76 OBD159_2527 GAGGACAACAAGAAGTCGGCTAATA OBD159_2525_2527 -0.002323473
77 OBD159_2531 TGAGCATTCAAATCTCCTAATCACCT OBD159_2529_2531 -0.0008648
78 OBD159_2535 CAGTGTAACCTTTATTTTCCACAAA OBD159_2533_2535 -0.002098785
79 OBD159_2539 CCCTCCTGGTGAGAAGTCATCTG OBD159_2537_2539 -0.003820154
80 OBD159_2543 GACTTGGAATGCCTTGGACTTGCTTA OBD159_2541_2543 -0.003551293
81 OBD159_2547 GCTACTCGGAAACACTCAGAGAGCGA OBD159_2545_2547 -0.003903276
82 OBD159_2551 CTGCCTGAGTTACAACAGAATCCTTT OBD159_2549_2551 -0.002161088
83 OBD159_2555 GACAAGGATTCTGCCCACAAGGC OBD159_2553_2555 -0.002838208
84 OBD159_2559 GCTACCCTATGAACACATTTGCCT OBD159_2557_2559 -0.005497194
85 OBD159_2563 GCAATGGCTGGGAAATAGAAGGCATA OBD159_2561_2563 -0.00207864
86 OBD159_2567 GCCAACTTCTCTTCCAACTCTAAAAT OBD159_2565_2567 -0.003056695
87 OBD159_2571 CATAATGTTTCTGAGGTTCACCAATG OBD159_2569_2571 -0.003720466
88 OBD159_2575 GAAAGGATTAGAGAAGAGCAAGAGTG OBD159_2573_2575 -0.002178565
89 OBD159_2579 TAGTTCTGAATGTGTCGGTGGCTG OBD159_2577_2579 -0.005320412
90 OBD159_2583 ACCTCCCTCGCTCCAAGACCAGA OBD159_2581_2583 -0.002636746
91 OBD159_2587 GCCTGGGTGACAGAGCAAAACTC OBD159_2585_2587 -0.004348047
92 OBD159_2591 GGTGAAACGGACATACGCATAAAGCG OBD159_2589_2591 -0.002630004
93 OBD159_2595 GGATGTGCCTCTTTGGGAGTGAGAAA OBD159_2593_2595 -0.003958004
94 OBD159_2599 TGGGACACCTTCTGCTGCTTTCAGTG OBD159_2597_2599 -0.000618082
95 OBD159_2603 CACTTTCACTCTCAGGTGTGTCCCTA OBD159_2601_2603 -0.003881393
96 OBD159_2607 TGTGCTTGGTTGAACTGAATCATT OBD159_2605_2607 -0.00219355
97 OBD159_2611 GCTCTGCTCTCCCTATCCTTGGC OBD159_2609_2611 -0.003270066
98 OBD159_2615 GCTCTGAGAAAAGGAGTTAGCAAGCA OBD159_2613_2615 -0.002503083
99 OBD159_2619 GTAGTCCCAGCACTTTAGGAGGC OBD159_2617_2619 -0.002477286
100 OBD159_2623 TGCTATGGGTGGTGACAGTTGTGTAT OBD159_2621_2623 -0.00348659
101 OBD159_2627 CTGAAAATCCATTGACTATCTTCTCG OBD159_2625_2627 -0.004391726
102 OBD159_2631 CTGAAAACCTAAAAGGGAACTGAACA OBD159_2629_2631 -0.002075607
103 OBD159_2635 TATGTTACACCCCTTGGCTACCCAGC OBD159_2633_2635 -0.001633126
104 OBD159_2639 GCTGTTTCCTTATCCAAGTCTCAGAT OBD159_2637_2639 -0.001847004
105 OBD159_2643 TACGGAAGATGGAAGTGAGGTGC OBD159_2641_2643 -0.005178354
106 OBD159_2647 GATTTCATTACTATTGTTCTAAGC OBD159_2645_2647 -0.002421223
107 OBD159_2651 CCTCCAAGTTCTCCTTTTCGTTAC OBD159_2649_2651 -0.003872628
108 OBD159_2655 AGCACTTTGGGAGGCTGAGGCAG OBD159_2653_2655 -0.0022703
109 OBD159_2659 CAGTGTCTCTGACGCACAAATGCCTA OBD159_2657_2659 -0.002830423
110 OBD159_2663 GGGAAACTGTGACTCAACCTCAGGAA OBD159_2661_2663 -0.002003145
111 OBD159_2591 GGTGAAACGGACATACGCATAAAGCG OBD159_2589_2591 -0.001625766
112 OBD159_2667 GTGAGATAACTGAGGCTCTAAGAACT OBD159_2665_2667 -0.003832225
113 OBD159_2671 GGGCGACAAAGTGAAACCCTCATT OBD159_2669_2671 -0.00138426
114 OBD159_2675 GGACTACAGGCGTGAGCCACCAC OBD159_2673_2675 -0.002488264
115 OBD159_2679 CTATCGGAGGGCGGGTCCCAATA OBD159_2677_2679 -0.001244694
116 OBD159_2683 TGAAGCCTGCCCACAAGGTCAGC OBD159_2681_2683 -0.00110431
117 OBD159_2687 AACTATCTATCCGTCTGTCTTCTGGC OBD159_2685_2687 -0.001064378
118 OBD159_2691 TTTCGGCAGTAGCCAATCAGAGACCC OBD159_2689_2691 -0.003172111
119 OBD159_2695 TACCATCCTCTGCCCTTCAACATA OBD159_2693_2695 -0.002904958
120 OBD159_2699 GGGCAAATACCATCGCTTTCCCCTA OBD159_2697_2699 -0.000994852
表4.a8
   基因
1 rs2760501; rs6668586
2 FAM160B1; TRUB1; rs968847
3 FAM222A; rs763757845
4 MTHFD1; ZBTB25; rs34181110; rs2236225; rs2281603
5 SCNN1B; SCNN1G; rs137853342
6 DPYSL5; rs1371614
7 CXADR
8 CXADR
9 CXADR
10 ANKRD55; rs159572; rs6859219; rs10065637; rs71624119; rs10213692; rs7731626; rs28722705
11 ANKRD55; rs159572; rs6859219; rs10065637; rs71624119; rs10213692; rs7731626; rs28722705
12 ANKRD55; rs1020388; rs6859219; rs10065637; rs71624119; rs10213692; rs7731626; rs28722705; rs159572; rs4700060
13 FBXO16; FZD3
14 SLC6A17; rs775085213
15 KCNC4; SLC6A17; UBL4B; rs775085213; rs375380880
16 FGFR2; rs755001161; rs148514974; rs10510097; rs4752569; rs3750817; rs7895676; rs10736303; rs11200014; rs2981579; rs1078806; rs2981578; rs35054928; rs2981575; rs1219648; rs1219642; rs2912774; rs2936870; rs45631563; rs2420946; rs3135724; rs2981582; rs3135718
17 ZMYND11; rs606231267; rs1060499626; rs1135401797
18 CNTN5; rs1394461
19 SV2B; rs886144
20 IL4R; rs769790595; rs2107356; rs3785356; rs1805010; rs764099093; rs370524692; rs3024647
21 BBX; rs670752
22 GTF2E1; rs322458
23 GAFA3; PGM2
24 ARHGAP36; ENOX2
25 EFNB1; rs5937157
26 DCD; LACRT; PPP1R1A
27 MTHFD1; ZBTB25; rs34181110; rs2236225; rs2281603
28 C6orf211; CCDC170; RMND1; rs9479072; rs6933660; rs1971256; rs9479055; rs6931664; rs9479068; rs7761420; rs9478217; rs7753676
29 CADM2; rs9829032
30 ARRDC4
31 PDXDC1; rs4003228
32 rs12554199
33 IBTK; rs10806235
34 CTSB; FDFT1; GATA4; NEIL2; rs1466785; rs804279; rs804270; rs148057216; rs8191664; rs7001819; rs2645429; rs2645424; rs6601615; rs8898; rs762727745; rs13332; rs569307763; rs2740594; rs747940576; rs12338
35 FRMD4A; rs12220909; rs1218412
36 rs6576507; rs547843
37 GSPT1; RP11-166B2.1; SNX29; TNFRSF17; rs12922317
38 KDM8; NSMCE1; rs9940555
39 BCAT2; HSD17B14; NUCB1; PLEKHA4; PPP1R15A; TULP2; rs56104184; rs17272694; rs557806; rs595982; rs7260579
40 CFAP61; CRNKL1  A20; RIN2; rs1057519885
41 NKX2-2; NKX2-4
42 rs13113999
43 GAFA3; PGM2
44 PLS3; rs201386833
45 AGBL4; SPATA6; rs2803270
46 AGBL4; SPATA6; rs2803270
47 NLGN4X; rs756651509; rs2290488
48 SLC35G3; UNC45B; rs370424081
49 GRIK1; rs455804
50 ELMO1; rs6942726
51 ANKRD55; rs715180
52 RAPGEF5; STEAP1B
53 ZHX2; rs10108684
54 C8orf48
55 ATP6V1G1; C9orf91; rs10513249; rs10817638
56 rs3788853; rs56204867
57 NEDD4L; rs4149601
58 KLF6; rs705464
59 WAPAL; rs7075426; rs731171; rs182554582
60 GABARAPL1; KLRD1; TMEM52B
61 TMTC2; rs7961953
62 rs11116045; rs1545843
63 SV2B; rs886144
64 GRIN2A; rs4107019; rs11644461; rs7192557
65 CTNNA2; rs6752828
66 SNAP25; rs363043; rs363050; rs362584; rs797044873; rs3787283; rs3746544; rs1051312
67 IQCJ; IQCJ-SCHIP1; rs13064773
68 FAT4; rs587777724; rs587777725; rs1039808
69 TREM1; TREML4; rs74851542; rs2234246; rs6910730; rs2234237; rs3789205; rs9471535
70 FARS2; rs397514612; rs775690041
71 AUTS2; rs4718886
72 PDP1; rs7006531
73 DOCK11; IL13RA1
74 rs35306388; rs442309; rs58600253
75 UGT8; rs78557978
76 C6orf211; RMND1; rs370863743
77 GHR; rs6898743
78 PPP6C; SCAI
79 EFHC2; rs7055196
80 PCDHGA1; PCDHGA2; PCDHGA3; TAF7; rs563151485; rs61749035
81 GPX5; GPX6; rs2394103; rs35701070; rs974334; rs13191038; rs406113; rs6456823; rs11757235
82 HZGJ; PPP3R1; rs2120335; rs12052801; rs1822469; rs12465425
83 GABRG2; rs211037; rs397514737; rs121909672; rs1060501889; rs121909674
84 SYNPR; rs13098482
85 CHIT1; rs871799; rs3831317; rs2297950; rs137852607
86 PLXNA2; rs11578508; rs841865; rs752016; rs1327175; rs2478813; rs2498028; rs716461
87 PITPNM2; rs1727294; rs1727307; rs7132277
88 C2CD5; ETNK1
89 OLFM4; rs9568797
90 E2F6; GREB1; rs77294520
91 BPI; KIAA1755; rs6024947; rs6123471; rs6127471; rs4811602; rs877600; rs1341023; rs5743507; rs4358188
92 ZFP42; rs6825162; rs6837349; rs4862848
93 CNKSR3; IPCEF1; OPRM1
94 RAPGEF5; STEAP1B
95 ST18; rs2360806
96 LRRTM4; rs61354037
97 OLFM2; PIN1; rs2233682; rs2287838; rs779032127
98 rs140236920
99 LYZL2; MAP3K8
100 RAD51B; rs1570106; rs17105278; rs4902562; rs3784099; rs2208397; rs911263; rs2104047; rs1950897; rs11158728; rs927220; rs61985136; rs8017304; rs1956529; rs4902566
101 SLFN11; SLFN5
102 C6orf211; RMND1; ZBTB2; rs115079861; rs886037773; rs886037771; rs397515421; rs1057519299; rs773470671; rs144972972; rs771894262; rs606231472; rs886037772; rs370863743
103 THBS2; rs9406328
104 GNG2; rs8015138
105 SLC6A17; rs375380880; rs775085213
106 ST6GALNAC3; rs915404
107 LAMA3; TTC39C
108 IQCJ; IQCJ-SCHIP1; rs13064773
109 IQCJ; IQCJ-SCHIP1; rs13064773
110 FBXW7; rs522743
111 ZFP42; rs6825162; rs6837349; rs4862848
112 ARMC1; MTFR1
113 ATP6V1G1; C9orf91; rs10513249; rs10817638
114 BAG1; CHMP5; NFX1
115 BCOR; rs2968915
116 BCOR; rs2968915
117 ELMO1; rs6942726
118 C14orf159; RPS6KA5; rs1286150; rs11848357
119 rs971257; rs116677506
120 CAMKMT; SIX3
表4.a9
      探針 基因座
121 ORF144_2_56308065_56316578_56344324_56347884_FF CCDC85A; rs6747380
122 ORF144_X_103107164_103111839_103158530_103163550_FF BEX4; NXF3
123 ORF146_1_229796281_229797522_229849427_229855718_FR GALNT2; rs4925506
124 ORF148_3_40973608_40983324_41025836_41032545_FR rs62259232; rs35360328
125 ORF148_5_56051850_56055700_56069488_56074299_FR ANKRD55; rs715180
126 ORF148_8_22339630_22342765_22370928_22373682_FF PIWIL2; SLC39A14; rs879253763
127 ORF149_4_88278877_88282499_88335985_88339586_FR PPM1K; rs6819344; rs7661312; rs2869926; rs881561; rs893971; rs17732955; rs9637599; rs4423843; rs4693210; rs958325; rs13128713; rs6845249; rs34813495; rs7655241; rs28406500; rs10024717; rs4693946; rs7678928; rs13151250; rs28375859; rs11931633; rs9995984; rs10018448; rs1440581; rs1440580; rs17013995; rs17789621; rs7676986; rs7677533; rs7660693; rs6841731; rs1899132; rs28789746; rs9998450; rs4693947; rs28884607; rs6532063; rs1595911; rs1595910; rs1808860; rs1808859; rs28504259; rs1545207; rs10022462; rs17014018; rs4693211; rs4693950; rs12512051
128 ORF15_1_110155952_110164041_110243262_110248847_FF KCNC4; SLC6A17; UBL4B; rs775085213; rs375380880
129 ORF15_1_186762629_186769807_186806428_186824334_RF PLA2G4A; rs4140564
130 ORF15_1_210312443_210322312_210344738_210348320_RR HHAT; rs116161686; rs34585985
131 ORF15_12_13269291_13270343_13311794_13314398_RF EMP1; rs1479119
132 ORF15_12_13311794_13314398_13342225_13351549_FR EMP1; rs1479119
133 ORF15_2_11479893_11482767_11532162_11535545_RF E2F6; GREB1; rs77294520
134 ORF15_2_5924503_5932342_5965887_5980313_FF rs10929925; rs16864170
135 ORF15_4_37859966_37862832_37914414_37919908_RR GAFA3; PGM2; PTTG2; TBC1D1; rs17578878; rs35859249
136 ORF15_6_134212503_134214388_134270140_134271366_RF SGK1; rs1743966; rs1009840; rs4896030; rs9493873
137 ORF15_6_84752549_84755954_84775145_84786636_FF TBX18; rs869320679; rs797045022; rs77693245
138 ORF15_8_119855069_119857313_119882110_119888009_FR DEPTOR; DSCC1; TAF2
139 ORF15_X_115878688_115881423_115936015_115945579_RF PLS3; rs201386833
140 ORF150_6_89493632_89495030_89546588_89550753_RF ANKRD6; LYRM2; rs78571182
141 ORF150_Y_11007821_11009157_11075743_11080103_FR rs111611512
142 ORF152_2_38148629_38155476_38179203_38180978_FR ATL2; CYP1B1
143 ORF152_5_26952527_26963487_26999889_27004744_FR CDH9; rs201058683
144 ORF152_5_38608515_38611090_38682143_38683313_FF LIFR; rs185111230
145 ORF153_5_26952527_26963487_26999889_27004744_FF CDH9; rs201058683
146 ORF153_8_29144477_29147633_29216944_29221322_FR KIF13B; rs75609241
147 ORF154_12_82572942_82575790_82624217_82631901_FR METTL25; TMTC2
148 ORF155_2_27492451_27495056_27542894_27545242_FF AC109829.1; FNDC4; GCKR; rs8395; rs2303369; rs704795; rs780090; rs146175795; rs813592; rs1260320; rs149847328; rs2293572; rs2293571; rs1260326; rs3817588; rs4425043; rs6547692; rs780096; rs780095; rs780094; rs780093; rs780092; rs814295; rs11681351; rs704790; rs8179252; rs1260334; rs1260333; rs1313566; rs2950835; rs200826320; rs2911711; rs6753534; rs4665985; rs4665987; rs12473139; rs4665991
149 ORF156_16_11987495_11990198_12005204_12009260_FR SNX29; rs12922317
150 ORF156_Y_11007821_11009157_11057559_11075743_FF rs111611512
151 ORF157_1_229796281_229797522_229859020_229862315_FR GALNT2; rs4925506
152 ORF158_16_11987495_11990198_12005204_12009260_FF SNX29; rs12922317
153 ORF158_6_73669509_73673385_73688989_73690148_RF CD109; SLC17A5
154 ORF158_9_33299656_33304064_33317596_33319558_RR CHMP5; NFX1
155 ORF158_X_103336904_103343604_103357970_103363324_RR TCEAL7; WBP5
156 ORF159_10_89863078_89864649_89921840_89926215_FF KIF20B; rs181778161
157 ORF16_6_134270140_134271366_134285274_134289662_FF SGK1; rs9493873
158 ORF16_8_21022651_21025530_21074365_21076495_RR rs7015657; rs500816
159 ORF16_9_94791100_94792692_94818790_94822742_RF C9orf3; rs7026071
160 ORF16_X_118719838_118725132_118772495_118775196_RF IL13RA1; rs3121672; rs2250747
161 ORF16_X_134227323_134230233_134251763_134253313_RR CCDC160; PHF6
162 ORF160_10_110775235_110786527_110797638_110800058_RR RBM20; rs267607001; rs183007628
163 ORF160_7_22390272_22396878_22452771_22454987_FR RAPGEF5; STEAP1B
164 ORF164_6_37603737_37604889_37629301_37631523_FF MDGA1; rs9462343
165 ORF164_8_97885717_97888667_97935143_97937399_FF MATN2; rs6987225
166 ORF166_11_101998219_102000306_102025025_102027879_FF C11orf70; KIAA1377
167 ORF166_12_54589309_54591607_54623187_54631741_FR LACRT; PPP1R1A
168 ORF167_12_46922957_46926200_46952555_46954006_RR AMIGO2; SLC38A4
169 ORF167_15_65512147_65515718_65573794_65596385_RR DPP8; PTPLAD1; VWA9; rs352479; rs9635366; rs352476; rs2456015; rs2456009; rs12916360; rs11632310; rs12906196; rs7165102
170 ORF167_X_11366661_11385597_11459265_11462297_RR AMELX; ARHGAP6
171 ORF168_5_7555641_7557907_7606244_7610178_RR ADCY2; rs12522444; rs11134242; rs4530734; rs12519539
172 ORF168_6_45815741_45822184_45845191_45849862_RR CLIC5; RUNX2
173 ORF169_4_21879694_21883839_21965631_21973272_RR GPR125; KCNIP4
174 ORF169_8_97885717_97888667_97933550_97935143_FR MATN2; rs6987225
175 ORF17_1_110155952_110164041_110184326_110187411_FF SLC6A17; rs375380880; rs775085213
176 ORF17_1_110155952_110164041_110248847_110251734_FR KCNC4; SLC6A17; UBL4B; rs775085213; rs375380880
177 ORF17_12_16574208_16575957_16629200_16637265_RF LMO3; MGST1; rs10505799
178 ORF17_13_53034265_53036683_53047390_53050193_FF OLFM4; rs12552; rs9568797
179 ORF17_15_22830640_22835640_22890866_22893120_FF CYFIP1; NIPA1; NIPA2; rs4778334; rs371775791; rs576755299
180 ORF17_16_11987495_11990198_12005204_12009260_FF SNX29; rs12922317
181 ORF17_2_169092304_169105070_169146919_169154561_FR DHRS9; LRP2; rs80338753; rs202057289; rs80338754; rs764880181; rs4667594; rs786205122; rs2075252
182 ORF17_9_94818790_94822742_94893440_94896165_FF C9orf3; rs10993397; rs10761362; rs4385527
183 ORF17_X_1174946_1177246_1240440_1242375_RF CRLF2; CSF2RA
184 ORF17_X_5594024_5600926_5621246_5623679_FR rs5916200
185 ORF170_3_106246431_106249672_106313861_106318469_FR rs12487066
186 ORF170_6_157307294_157314514_157337743_157340036_RF TMEM242; ZDHHC14
187 ORF170_8_113381107_113383608_113436243_113437347_RR CSMD3; rs189590409
188 ORF171_12_26016038_26021057_26034684_26036629_FR RASSF8; rs1546550
189 ORF172_2_129205308_129208404_129231919_129233302_RF rs1660895; rs13013037
190 ORF172_9_33252746_33260644_33317596_33319558_FR BAG1; CHMP5; NFX1; SPINK4; rs706118; rs3758271
191 ORF173_12_96219857_96223649_96237099_96241349_RF ELK3; rs4762284
192 ORF173_8_97885717_97888667_97943674_97946241_FF MATN2; rs6987225
193 ORF176_2_209659511_209662054_209735707_209738646_FF MAP2; rs9288410; rs146432517
194 ORF176_6_61648546_61654260_61698546_61699905_RF AL356135.1; KHDRBS2; rs140996952; rs76014404
195 ORF177_2_21342478_21344227_21387178_21390560_RF rs2337901; rs11897825
196 ORF177_3_78739183_78745105_78757303_78759810_FF ROBO1; rs919603543
197 ORF177_8_97811124_97813316_97885717_97888667_RF LAPTM4B; MATN2; rs6987225
198 ORF179_2_195583610_195589061_195630259_195633750_FR DNAH7; SLC39A10
199 ORF18_1_110155952_110164041_110268937_110272034_FF KCNC4; SLC6A17; UBL4B; rs775085213; rs375380880
200 ORF18_12_83891421_83896037_83954032_83957600_FF rs11116045; rs1545843
201 ORF18_2_11504797_11509096_11532162_11535545_RF E2F6; GREB1; rs77294520
202 ORF18_2_20297935_20303337_20328998_20331608_RR PUM2; rs111612372
203 ORF18_21_17391129_17392895_17437778_17439433_FF CXADR
204 ORF18_4_153693586_153700349_153764783_153769098_FF RNF175; TLR2; rs1898830; rs748086774; rs3804099; rs3804100; rs5743704; rs121917864; rs5743708; rs7656411
205 ORF18_6_134212503_134214388_134270140_134271366_RF SGK1; rs1743966; rs1009840; rs4896030; rs9493873
206 ORF18_6_162152986_162154134_162206360_162211749_RF PARK2; rs566229879; rs765648938; rs137853057; rs778798543; rs747984930
207 ORF18_X_37313041_37321250_37333766_37337668_FR FAM47C; PRRG1
208 ORF180_2_56308065_56316578_56390760_56394124_FF CCDC85A; rs186920977; rs6747380; rs17268785
209 ORF183_22_20770086_20774393_20816159_20817209_FR PI4KA; SERPIND1; rs777006911; rs587777759; rs5907; rs142451096; rs121912420; rs587777760
210 ORF183_8_9123942_9126289_9220259_9225462_FR ERI1; PPP1R3B; rs189798; rs9949; rs3748140; rs7011581; rs6998837; rs6999855; rs378974; rs440932; rs365309; rs3748136
211 ORF184_1_211433313_211435632_211464001_211470782_RF RD3; rs11579557
212 ORF184_10_89827266_89829504_89863078_89864649_RF KIF20B; rs181778161
213 ORF184_11_75861382_75864724_75932505_75943225_FF UVRAG; rs7933235
214 ORF184_5_167857386_167858550_167921706_167923030_FR TENM2; rs9647570
215 ORF185_17_16799136_16800747_16881471_16884846_FF CCDC144A; RP11-219A15.1
216 ORF186_6_73688989_73690148_73742434_73750026_FF CD109; SLC17A5
217 ORF187_6_151443530_151449164_151537463_151538576_FF C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256; rs9479055; rs6931664
218 ORF189_1_48532003_48539768_48603267_48618802_FR AGBL4; SPATA6; rs2803270
219 ORF19_1_110141802_110145853_110155952_110164041_RF SLC6A17; rs775085213
220 ORF19_1_223787115_223791224_223834661_223838535_RR CAPN2; TP53BP2
221 ORF19_12_13270343_13274324_13311794_13314398_RF EMP1; rs1479119
222 ORF19_15_22839534_22840551_22879924_22886427_RF CYFIP1; NIPA2; rs4778334; rs371775791; rs576755299
223 ORF19_18_12837148_12839042_12851275_12853060_RF PTPN2; rs514000; rs11875687; rs657555
224 ORF19_2_78763526_78765449_78804372_78809080_FR REG3G
225 ORF19_21_17391129_17392895_17434190_17435748_FF CXADR
226 ORF19_5_93562856_93565579_93582366_93583770_FF NR2F1; rs587777277
227 ORF19_X_115872740_115875445_115936015_115945579_RF PLS3; rs201386833
228 ORF190_1_48532003_48539768_48603267_48618802_FF AGBL4; SPATA6; rs2803270
229 ORF190_17_36192362_36195269_36216401_36221747_RR CCL3L3; CCL4L1; TBC1D3B; TBC1D3I
230 ORF190_4_175635137_175638077_175657671_175665421_RF GPM6A; rs13144140
231 ORF190_8_97885717_97888667_97911504_97913312_FF LAPTM4B; MATN2
232 ORF191_19_46459835_46460902_46479838_46481514_RF PNMAL1; PNMAL2; PPP5D1
233 ORF191_9_28333777_28339631_28374860_28379516_FF LINGO2; rs7851437
234 ORF194_4_15556941_15559956_15665131_15667839_RR CC2D2A; FBXL5; rs200904521; rs863225178; rs764719093; rs386833748; rs118204053; rs773881370; rs370880399; rs386833749; rs863225173; rs386833750; rs863225169; rs386833751; rs386833752; rs267606709; rs118204051; rs386833753; rs863225170; rs386833754; rs386833755; rs386833756; rs760918829; rs375278294; rs863225171; rs863225172; rs386833757; rs779823379; rs754586025; rs763735590; rs386833758; rs386833759; rs576298659; rs758036385; rs763486732; rs794729225; rs386833760; rs886044295; rs863225176; rs863225168; rs7684446; rs387907058; rs368720062; rs587779732; rs797045437; rs863225179; rs386833762; rs780673487; rs118204052; rs763425007; rs201502401; rs863225174; rs863225175; rs1134634
235 ORF195_8_97885717_97888667_97955459_97960176_FR MATN2; rs6987225
236 ORF197_9_33260644_33262136_33317596_33319558_RR BAG1; CHMP5; NFX1; rs706118; rs3758271
237 ORF197_X_101076588_101078760_101106636_101109429_FF CENPI; TMEM35; TRMT2B
238 ORF198_13_45792577_45800189_45859224_45860475_RR SIAH3; rs75061684
239 ORF198_14_73418771_73426644_73454993_73457655_RR HEATR4; NUMB
240 ORF198_2_164430286_164435469_164495161_164496648_FF GRB14; rs8192673
表4.b1
   Probe_Count_Total Probe_Count_Sig HyperG_Stats
121 35 4; 2 0.035189793; 0.255336195
122 17; 17 1; 2; 1; 2 0.350975055; 0.126473611; 0.350975055; 0.126473611
123 44 4; 3 0.063857117; 0.169607427
124 NA NA NA
125 72 5 0.087766242
126 52; 49 2; 2; 2; 2 0.276304155; 0.273929087; 0.276096976; 0.276409079
127 14 1 0.337131196
128 49; 68; 56 4; 8; 4 0.096088025; 0.005458299; 0.123346872
129 19 2 0.132230242
130 57 1 0.239596043
131 58 1; 3 0.234279681; 0.216530763
132 58 1; 3 0.234279681; 0.216530763
133 48; 40 4; 1; 4; 1 0.078104352; 0.267628012; 0.050377953; 0.314741981
134 NA NA NA
135 37; 37; 16; 40 5; 8; 5; 8; 1; 2; 2; 3 0.010942367; 0.000107113; 0.010942367; 0.000107113; 0.343724359; 0.116490918; 0.261899069; 0.150241062
136 108 4; 1 0.198465555; 0.045253641
137 20 4; 5 0.005899409; 0.001067155
138 62; 63; 105 1; 1; 1 0.213548789; 0.208517986; 0.065089658
139 29 2; 5 0.211050406; 0.005560973
140 23; 23 1; 1 0.374075448; 0.374075448
141 NA NA NA
142 23; 34 4; 3; 4; 3 0.009574125; 0.055866229; 0.0324282; 0.117734198
143 30 3; 1 0.082195447; 0.363021342
144 9 1 0.255358235
145 30 3; 1 0.082195447; 0.363021342
146 50 1 0.255769837
147 9; 27 1; 1; 2; 1 0.255358235; 0.268692312; 0.197546356; 0.37173223
148 11; 21; 21 1; 1; 1 0.301350316; 0.37425716; 0.37425716
149 103 1; 3 0.069157027; 0.178958558
150 NA NA NA
151 44 4; 3 0.063857117; 0.169607427
152 103 1; 3 0.069157027; 0.178958558
153 34; 34 3; 3; 3; 3 0.103367502; 0.117734198; 0.103367502; 0.117734198
154 22; 28 5; 1; 5; 1 0.001196845; 0.375573766; 0.003522831; 0.369266824
155 4; 3 1; 1 0.14804367; 0.115907508
156 22 3 0.050708849
157 108 4; 1 0.198465555; 0.045253641
158 NA NA NA
159 90 2 0.16104703
160 13 2 0.076537269
161 26; 38 1; 1; 1; 1 0.375314357; 0.373699919; 0.340322106; 0.325888812
162 14 1 0.325643034
163 107; 149 3; 3 0.188257442; 0.096032365
164 23 1 0.376115439
165 24 6 0.000341358
166 13; 27 1; 1 0.314642613; 0.374553651
167 17; 21 2; 2 0.126473611; 0.164464127
168 23; 23 1; 1; 1; 1 0.374075448; 0.376115439; 0.374075448; 0.376115439
169 6; 18; 18 1; 1; 1; 1; 1 0.203777963; 0.357137933; 0.364965787; 0.357137933; 0.364965787
170 33; 35 1; 3; 1; 3 0.360592644; 0.112054294; 0.353195365; 0.123360639
171 90 3; 3  0.219233776; 0.208104371
172 33; 23 1; 1 0.35096223; 0.376115439
173 14; 21 1; 1 0.337131196; 0.37425716
174 24 6 0.000341358
175 68 8 0.005458299
176 49; 68; 56 4; 8; 4 0.096088025; 0.005458299; 0.123346872
177 5; 5  1; 1  0.166301763; 0.166301763
178 26 2 0.205329626
179 79; 44; 79 2; 1; 2 0.199035831; 0.291442657; 0.199035831
180 103 1; 3  0.069157027; 0.178958558
181 49; 70 2; 3; 1 0.276096976; 0.190339907; 0.151233777
182 90 2 0.16104703
183 3; 4 1; 1 0.108032075; 0.138432982
184 NA NA NA
185 NA NA NA
186 98; 77 1; 2; 1; 2 0.080334308; 0.135364458; 0.14587104; 0.206032338
187 12 1; 2  0.302214299; 0.076075379
188 48 1 0.288729231
189 NA NA NA
190 12; 22; 28; 8 4; 1; 5; 1; 5; 1; 1 0.000827358; 0.314913912; 0.001196845; 0.375573766; 0.003522831; 0.369266824; 0.236185646
191 13 2; 3 0.076537269; 0.013853987
192 24 6 0.000341358
193 60 5; 7 0.05512946; 0.009185497
194 7; 20 1; 1 0.215038813; 0.366490901
195 NA NA NA
196 29 1 0.371537436
197 27; 24 2; 6 0.212429916; 0.000341358
198 61; 81 2; 3; 3; 3 0.26657373; 0.222001213; 0.227770757; 0.222648484
199 49; 68; 56 4; 8; 4 0.096088025; 0.005458299; 0.123346872
200 NA NA NA
201 48; 40 4; 1; 4; 1 0.078104352; 0.267628012; 0.050377953; 0.314741981
202 54 5; 6 0.040491239; 0.018151611
203 45 6; 1 0.006017292; 0.285503815
204 22; 30 2; 3; 1 0.158567173; 0.050708849; 0.363021342
205 108 4; 1 0.198465555; 0.045253641
206 19 1 0.362286681
207 16; 4 1; 1 0.343724359; 0.138432982
208 35 4; 2 0.035189793; 0.255336195
209 103; 85 1; 1 0.069157027; 0.117044316
210 62; 136 1; 1 0.213548789; 0.024430673
211 20 1 0.366490901
212 22 3 0.050708849
213 14 1; 1 0.325643034; 0.337131196
214 43 1 0.297350686
215 24; 72 1; 1 0.375122937; 0.166484848
216 34; 34 3; 3; 3; 3 0.103367502; 0.117734198; 0.103367502; 0.117734198
217 63; 46; 75 3; 5; 2; 4; 3; 5 0.216848517; 0.076682692; 0.273777277; 0.084172061; 0.228845362; 0.1125292
218 93; 9 1; 5; 4 0.093070545; 0.156450038; 0.000317369
219 68 8 0.005458299
220 35; 35 1; 1 0.353195365; 0.353195365
221 58 1; 3 0.234279681; 0.216530763
222 79; 79 2; 2 0.199035831; 0.199035831
223 62 1 0.213548789
224 3 3; 2 0; 0.001770535
225 45 6; 1 0.006017292; 0.285503815
226 20 1; 2 0.366490901; 0.155331399
227 29 2; 5 0.211050406; 0.005560973
228 93; 9 1; 5; 4 0.093070545; 0.156450038; 0.000317369
229 68; 70; 76; 36 1; 1; 1; 1 0.184410962; 0.175291065; 0.149832643; 0.349116343
230 68 3; 4  0.224345313; 0.163371308
231 27; 24 2; 6 0.212429916; 0.000341358
232 28; 32; 32 3; 4; 3; 4; 3; 4 0.071800115; 0.02285211; 0.09275567; 0.033810966; 0.09275567; 0.033810966
233 20 6; 4 7.69e-05; 0.007618647
234 25; 39 1; 1 0.375519541; 0.335652067
235 24 6 0.000341358
236 12; 22; 28 4; 1; 5; 1; 5; 1 0.000827358; 0.314913912; 0.001196845; 0.375573766; 0.003522831; 0.369266824
237 26; 23; 22 1; 1; 1 0.375314357; 0.374075448; 0.372324987
238 56 3; 2 0.199907871; 0.267835203
239 24; 24 1; 1 0.375945017; 0.375945017
240 11 1 0.288260522
表4.b2
   FDR_HyperG Percent_Sig logFC AveExpr
121 0.375519541; 0.376115439 11.43; 5.71 0.49794395 0.49794395
122 0.375519541; 0.376115439; 0.375519541; 0.376115439 5.88; 11.76; 5.88; 11.76 0.574972969 0.574972969
123 0.375519541; 0.376115439 9.09; 6.82 0.676345396 0.676345396
124 NA NA 0.56703579 0.56703579
125 0.375519541 6.94 0.498601338 0.498601338
126 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.85; 3.85; 4.08; 4.08 0.536696835 0.536696835
127 0.376115439 7.14 0.605502672 0.605502672
128 0.376115439; 0.217379602; 0.376115439 8.16; 11.76; 7.14 0.555166048 0.555166048
129 0.375519541 10.53 0.560633088 0.560633088
130 0.375519541 1.75 0.523774327 0.523774327
131 0.375519541; 0.376115439 1.72; 5.17 0.576323107 0.576323107
132 0.375519541; 0.376115439 1.72; 5.17 0.520125142 0.520125142
133 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.33; 2.08; 10; 2.5 0.572693527 0.572693527
134 NA NA 0.575060601 0.575060601
135 0.357678624; 0.013656923; 0.357678624; 0.013656923; 0.375519541; 0.376115439; 0.375519541; 0.376115439 13.51; 21.62; 13.51; 21.62; 6.25; 12.5; 5; 7.5 0.537190811 0.537190811
136 0.375519541; 0.376115439 3.7; 0.93 0.516964113 0.516964113
137 0.242080288; 0.077749847 20; 25 0.584221965 0.584221965
138 0.375519541; 0.375519541; 0.375519541 1.61; 1.59; 0.95 0.492507488 0.492507488
139 0.375519541; 0.217379602 6.9; 17.24 0.551580907 0.551580907
140 0.375519541; 0.375519541 4.35; 4.35 0.554862478 0.554862478
141 NA NA 0.582760434 0.582760434
142 0.357661967; 0.376115439; 0.375519541; 0.376115439 17.39; 13.04; 11.76; 8.82 0.498500581 0.498500581
143 0.375519541; 0.376115439 10; 3.33 0.671204956 0.671204956
144 0.375519541 11.11 0.505781679 0.505781679
145 0.375519541; 0.376115439 10; 3.33 0.627338652 0.627338652
146 0.376115439 2 0.519548665 0.519548665
147 0.375519541; 0.376115439; 0.375519541; 0.376115439 11.11; 11.11; 7.41; 3.7 0.540254875 0.540254875
148 0.376115439; 0.376115439; 0.376115439 9.09; 4.76; 4.76 0.651040571 0.651040571
149 0.375519541; 0.376115439 0.97; 2.91 0.558410651 0.558410651
150 NA NA 0.586811279 0.586811279
151 0.375519541; 0.376115439 9.09; 6.82 0.88524663 0.88524663
152 0.375519541; 0.376115439 0.97; 2.91 0.569679093 0.569679093
153 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.82; 8.82; 8.82; 8.82 0.488859424 0.488859424
154 0.069549998; 0.376115439; 0.184244052; 0.376115439 22.73; 4.55; 17.86; 3.57 0.508181318 0.508181318
155 0.376115439; 0.376115439 25; 33.33 0.506933415 0.506933415
156 0.376115439 13.64 0.620446381 0.620446381
157 0.375519541; 0.376115439 3.7; 0.93 0.500746342 0.500746342
158 NA NA 0.498126377 0.498126377
159 0.376115439 2.22 0.670441293 0.670441293
160 0.375519541 15.38 0.523587776 0.523587776
161 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.85; 3.85; 2.63; 2.63 0.536833953 0.536833953
162 0.375519541 7.14 0.573209773 0.573209773
163 0.375519541; 0.375519541 2.8; 2.01 0.791377185 0.791377185
164 0.376115439 4.35 0.520612115 0.520612115
165 0.029015407 25 0.535238893 0.535238893
166 0.375519541; 0.375519541 7.69; 3.7 0.513829718 0.513829718
167 0.376115439; 0.376115439 11.76; 9.52 0.654409102 0.654409102
168 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.35; 4.35; 4.35; 4.35 0.496111451 0.496111451
169 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 16.67; 5.56; 5.56; 5.56; 5.56 0.531846872 0.531846872
170 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.03; 9.09; 2.86; 8.57 0.530818677 0.530818677
171 0.375519541; 0.376115439 3.33; 3.33 0.55374233 0.55374233
172 0.376115439; 0.376115439 3.03; 4.35 0.542210968 0.542210968
173 0.376115439; 0.376115439 7.14; 4.76 0.551966491 0.551966491
174 0.029015407 25 0.53664704 0.53664704
175 0.217379602 11.76 0.537986332 0.537986332
176 0.376115439; 0.217379602; 0.376115439 8.16; 11.76; 7.14 0.510248727 0.510248727
177 0.375519541; 0.375519541 20; 20 0.502927603 0.502927603
178 0.376115439 7.69 0.517900142 0.517900142
179 0.376115439; 0.376115439; 0.376115439 2.53; 2.27; 2.53 0.517060093 0.517060093
180 0.375519541; 0.376115439 0.97; 2.91 0.550973282 0.550973282
181 0.375519541; 0.376115439; 0.376115439 4.08; 6.12; 1.43 0.508324657 0.508324657
182 0.376115439 2.22 0.62763647 0.62763647
183 0.375519541; 0.375519541 33.33; 25 0.547714198 0.547714198
184 NA NA 0.529013394 0.529013394
185 NA NA 0.52084086 0.52084086
186 0.375519541; 0.376115439; 0.375519541; 0.376115439 1.02; 2.04; 1.3; 2.6 0.608493429 0.608493429
187 0.375519541; 0.376115439 8.33; 16.67 0.570976711 0.570976711
188 0.375519541 2.08 0.499117065 0.499117065
189 NA NA 0.505254484 0.505254484
190 0.069549998; 0.376115439; 0.069549998; 0.376115439; 0.184244052; 0.376115439; 0.375519541 33.33; 8.33; 22.73; 4.55; 17.86; 3.57; 12.5 0.683547978 0.683547978
191 0.375519541; 0.376115439 15.38; 23.08 0.627554365 0.627554365
192 0.029015407 25 0.539962942 0.539962942
193 0.375519541; 0.275564898 8.33; 11.67 0.577920661 0.577920661
194 0.375519541; 0.375519541 14.29; 5 0.494528263 0.494528263
195 NA NA 0.552975716 0.552975716
196 0.375519541 3.45 0.518597304 0.518597304
197 0.376115439; 0.029015407 7.41; 25 0.535869894 0.535869894
198 0.375519541; 0.376115439; 0.375519541; 0.376115439 3.28; 4.92; 3.7; 3.7 0.547664462 0.547664462
199 0.376115439; 0.217379602; 0.376115439 8.16; 11.76; 7.14 0.542692413 0.542692413
200 NA NA 0.550722797 0.550722797
201 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.33; 2.08; 10; 2.5 0.636516912 0.636516912
202 0.375519541; 0.376115439 9.26; 11.11 0.565299033 0.565299033
203 0.242080288; 0.376115439 13.33; 2.22 0.500923703 0.500923703
204 0.375519541; 0.376115439; 0.376115439 9.09; 13.64; 3.33 0.526105484 0.526105484
205 0.375519541; 0.376115439 3.7; 0.93 0.754692971 0.754692971
206 0.375519541 5.26 0.511869617 0.511869617
207 0.375519541; 0.375519541 6.25; 25 0.506803758 0.506803758
208 0.375519541; 0.376115439 11.43; 5.71 0.517919559 0.517919559
209 0.375519541; 0.375519541 0.97; 1.18 0.508803409 0.508803409
210 0.375519541; 0.37551954 1.61; 0.74 0.50748688 0.50748688
211 0.375519541 5 0.492873937 0.492873937
212 0.376115439 13.64 0.636576789 0.636576789
213 0.375519541; 0.376115439 7.14; 7.14 0.525893371 0.525893371
214 0.376115439 2.33 0.669996472 0.669996472
215 0.375519541; 0.375519541 4.17; 1.39 0.514514317 0.514514317
216 0.375519541; 0.376115439; 0.375519541; 0.376115439 8.82; 8.82; 8.82; 8.82 0.72143182 0.72143182
217 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 4.76; 7.94; 4.35; 8.7; 4; 6.67 0.533097441 0.533097441
218 0.375519541; 0.376115439; 0.029015407 1.08; 5.38; 44.44 0.546782401 0.546782401
219 0.217379602 11.76 0.565839306 0.565839306
220 0.375519541; 0.375519541 2.86; 2.86 0.525833608 0.525833608
221 0.375519541; 0.376115439 1.72; 5.17 0.557894771 0.557894771
222 0.376115439; 0.376115439 2.53; 2.53 0.602870802 0.602870802
223 0.375519541 1.61 0.548038418 0.548038418
224 0; 0.082088441 100; 100 0.597004784 0.597004784
225 0.242080288; 0.376115439 13.33; 2.22 0.553333021 0.553333021
226 0.375519541; 0.376115439 5; 10 0.551890023 0.551890023
227 0.375519541; 0.217379602 6.9; 17.24 0.560179256 0.560179256
228 0.375519541; 0.376115439; 0.029015407 1.08; 5.38; 44.44 0.602757851 0.602757851
229 0.375519541; 0.375519541; 0.375519541; 0.375519541 1.47; 1.43; 1.32; 2.78 0.506882645 0.506882645
230 0.375519541; 0.376115439 4.41; 5.88 0.638332442 0.638332442
231 0.376115439; 0.029015407 7.41; 25 0.554106903 0.554106903
232 0.375519541; 0.376115439; 0.375519541; 0.376115439; 0.375519541; 0.376115439 10.71; 14.29; 9.38; 12.5; 9.38; 12.5 0.509029721 0.509029721
233 0.008046243; 0.242844385 30; 20 0.570068001 0.570068001
234 0.375519541; 0.375519541 4; 2.56 0.507418689 0.507418689
235 0.029015407 25 0.5198147 0.5198147
236 0.069549998; 0.376115439; 0.069549998; 0.376115439; 0.184244052; 0.376115439 33.33; 8.33; 22.73; 4.55; 17.86; 3.57 0.665092008 0.665092008
237 0.375519541; 0.375519541; 0.375519541 3.85; 4.35; 4.55 0.517555894 0.517555894
238 0.375519541; 0.376115439 5.36; 3.57 0.498659086 0.498659086
239 0.376115439; 0.376115439 4.17; 4.17 0.569145704 0.569145704
240 0.375519541 9.09 0.510819621 0.510819621
表4.b3
   t P值 adj.P.Val B FC FC_1 LS
121 12.85571368 0.0000000227 0.00000441 9.818282467 1.412199538 1.412199538 1
122 8.231552521 0.00000291 0.000144892 4.97091064 1.489649552 1.489649552 1
123 2.845380122 0.014816813 0.049671625 -3.722332957 1.598086385 1.598086385 1
124 10.12548163 0.000000317 0.0000196 7.175876122 1.481476549 1.481476549 1
125 3.978613043 0.001836205 0.006999235 -1.732533005 1.412843177 1.412843177 1
126 8.721949362 0.00000155 0.0000528 5.554231972 1.45064734 1.45064734 1
127 9.501845473 0.000000647 0.0000568 6.493327999 1.521508794 1.521508794 1
128 16.26352226 0.00000000165 0.00000233 12.28695 1.469337738 1.469337738 1
129 6.754609442 0.0000205 0.000279727 2.897404578 1.474916303 1.474916303 1
130 11.7906202 0.0000000597 0.00000731 8.858213504 1.437711621 1.437711621 1
131 4.33868702 0.000975622 0.007074083 -0.991794894 1.491044285 1.491044285 1
132 3.972131381 0.001871133 0.011231207 -1.654031412 1.434079637 1.434079637 1
133 3.955204751 0.00191528 0.007229568 -1.775415751 1.48729778 1.48729778 1
134 9.342186066 0.000000775 0.0000634 6.311747093 1.489740039 1.489740039 1
135 9.484575564 0.00000066 0.0000575 6.473815582 1.451144124 1.451144124 1
136 7.241225979 0.0000104 0.000178041 3.6008145 1.430940925 1.430940925 1
137 11.28626762 0.0000001 0.0000185 8.353950742 1.499230247 1.499230247 1
138 3.861809638 0.002267394 0.008226288 -1.946872616 1.406888006 1.406888006 1
139 3.169858859 0.008120403 0.031375457 -3.128902502 1.465690922 1.465690922 1
140 7.521461416 0.00000709 0.000138258 3.991565908 1.469028595 1.469028595 1
141 9.212944028 0.000000898 0.0000693 6.162784193 1.497712211 1.497712211 1
142 7.712692775 0.00000551 0.000117803 4.252371373 1.412744509 1.412744509 1
143 3.461607356 0.004713239 0.014405738 -2.68619229 1.592402406 1.592402406 1
144 15.36143873 0.00000000302 0.00000157 11.78564206 1.419892472 1.419892472 1
145 3.734296254 0.002858728 0.009823574 -2.181777444 1.544712822 1.544712822 1
146 5.979075369 0.0000656 0.001100184 1.775797396 1.433506717 1.433506717 1
147 9.091470009 0.000001 0.0000402 6.001316146 1.454229407 1.454229407 1
148 8.049768551 0.00000365 0.000167633 4.73774119 1.570300396 1.570300396 1
149 10.79174104 0.000000164 0.000025 7.867535813 1.472645979 1.472645979 1
150 8.606133556 0.00000183 0.000108855 5.438869381 1.501923445 1.501923445 1
151 2.961593771 0.011946063 0.042253055 -3.510770243 1.847080354 1.847080354 1
152 11.85164459 0.0000000586 0.0000136 8.885130644 1.484193396 1.484193396 1
153 11.41630184 0.0000000854 0.00000896 8.500433368 1.403334979 1.403334979 1
154 7.249747156 0.0000102 0.000176539 3.61284838 1.422256149 1.422256149 1
155 6.045822089 0.0000593 0.00102514 1.880551388 1.421026456 1.421026456 1
156 9.687346929 0.000000527 0.0000503 6.700976262 1.537350776 1.537350776 1
157 4.942191323 0.000342375 0.002016294 -0.012425986 1.41494536 1.41494536 1
158 13.98911851 0.00000000877 0.00000269 10.75468457 1.41237812 1.41237812 1
159 11.09507367 0.000000121 0.0000207 8.168379643 1.591559721 1.591559721 1
160 9.309736917 0.000000781 0.0000343 6.258410544 1.437525727 1.437525727 1
161 8.396894602 0.00000231 0.0000676 5.148192363 1.45078522 1.45078522 1
162 12.67393184 0.0000000267 0.00000483 9.660199745 1.487830083 1.487830083 1
163 2.813298857 0.015673542 0.0371907 -3.880370031 1.730725811 1.730725811 1
164 6.035610068 0.0000602 0.001037168 1.864565691 1.434563784 1.434563784 1
165 4.940370511 0.000347282 0.003485151 0.064476687 1.449182102 1.449182102 1
166 12.31154813 0.0000000369 0.00000569 9.338114755 1.427835442 1.427835442 1
167 5.995551995 0.000064 0.001082323 1.801715498 1.573971155 1.573971155 1
168 16.14993211 0.00000000170 0.00000121 12.33278112 1.410406913 1.410406913 1
169 13.01163173 0.0000000207 0.00000806 9.898762683 1.445778831 1.445778831 1
170 5.713793654 0.000099 0.001452511 1.35315809 1.444748805 1.444748805 1
171 7.78538955 0.00000513 0.000207293 4.391330899 1.467888443 1.467888443 1
172 3.034614526 0.010433466 0.038044461 -3.377210184 1.456202476 1.456202476 1
173 7.974342948 0.00000402 0.000177478 4.639802692 1.466082705 1.466082705 1
174 4.877852747 0.000385763 0.003742478 -0.043225865 1.450597271 1.450597271 1
175 15.8014145 0.00000000230 0.00000269 11.98274113 1.451944524 1.451944524 1
176 9.6824494 0.000000529 0.0000505 6.695539289 1.424295729 1.424295729 1
177 8.982291074 0.00000114 0.0000434 5.8707888 1.417086282 1.417086282 1
178 13.00991009 0.0000000207 0.00000806 9.897329162 1.431869629 1.431869629 1
179 3.771629684 0.002687951 0.014413366 -2.020655743 1.431036126 1.431036126 1
180 11.91225488 0.0000000554 0.0000134 8.940567065 1.465073741 1.465073741 1
181 6.970521521 0.0000154 0.000417149 3.266777256 1.422397464 1.422397464 1
182 7.906910766 0.00000438 0.000187785 4.551644468 1.545031734 1.545031734 1
183 13.91369902 0.00000000932 0.00000277 10.69488844 1.46176784 1.46176784 1
184 10.57073217 0.000000199 0.0000149 7.649470401 1.442942083 1.442942083 1
185 12.15610883 0.0000000442 0.000012 9.160755692 1.434791257 1.434791257 1
186 7.830227053 0.00000484 0.000199643 4.450698508 1.524666206 1.524666206 1
187 13.24846035 0.0000000169 0.0000073 10.09405586 1.48552894 1.48552894 1
188 10.51366843 0.000000211 0.0000154 7.589793821 1.413348323 1.413348323 1
189 9.142634001 0.000000973 0.0000728 6.080992301 1.419373704 1.419373704 1
190 6.674812554 0.0000229 0.000301937 2.778974192 1.6060847 1.6060847 1
191 9.469337194 0.000000671 0.0000579 6.456572713 1.544943807 1.544943807 1
192 4.908630686 0.000366289 0.00361381 0.009859863 1.45393517 1.45393517 1
193 7.319368215 0.00000951 0.000306736 3.758961631 1.492696293 1.492696293 1
194 3.570632974 0.003856746 0.012364677 -2.484294523 1.408860006 1.408860006 1
195 12.09931975 0.0000000466 0.0000122 9.1098815 1.467108649 1.467108649 1
196 12.25910518 0.0000000387 0.00000581 9.290719363 1.432561727 1.432561727 1
197 4.929323234 0.000353777 0.003529178 0.045481709 1.449816079 1.449816079 1
198 7.098710211 0.0000129 0.000370959 3.449548611 1.461717447 1.461717447 1
199 12.87639745 0.0000000233 0.00000866 9.785543484 1.456688511 1.456688511 1
200 25.56871967 0.00000000000802 0.00000021 17.07032839 1.464819394 1.464819394 1
201 5.282358199 0.000194846 0.001333347 0.568489571 1.554571435 1.554571435 1
202 7.909033584 0.00000437 0.000187525 4.554428423 1.47969418 1.47969418 1
203 7.949377976 0.00000405 0.0000965 4.56875885 1.415119319 1.415119319 1
204 12.26815 0.00000004 0.0000113 9.260418448 1.440036604 1.440036604 1
205 10.34036867 0.000000253 0.0000172 7.40673757 1.687272474 1.687272474 1
206 10.15869423 0.000000306 0.0000192 7.211842252 1.425896847 1.425896847 1
207 8.882389933 0.00000128 0.0000466 5.750208152 1.420898753 1.420898753 1
208 13.80179636 0.0000000102 0.00000289 10.60552951 1.4318889 1.4318889 1
209 5.751647537 0.0000919 0.000779941 1.343982865 1.422869558 1.422869558 1
210 5.136592019 0.000247594 0.001589372 0.321442156 1.421571713 1.421571713 1
211 8.109694021 0.0000033 0.0000843 4.779115391 1.407245405 1.407245405 1
212 10.45402001 0.000000232 0.0000309 7.52298061 1.554635956 1.554635956 1
213 6.629180754 0.0000245 0.000314786 2.710853914 1.439824897 1.439824897 1
214 4.288460006 0.001065705 0.007539514 -1.081806761 1.591069077 1.591069077 1
215 13.09997614 0.0000000184 0.00000396 10.02714542 1.42851315 1.42851315 1
216 11.17748674 0.000000112 0.0000198 8.248747382 1.648817612 1.648817612 1
217 14.87281024 0.00000000458 0.00000374 11.33855454 1.447032617 1.447032617 1
218 6.575892876 0.000027 0.000606493 2.689903304 1.460824029 1.460824029 1
219 13.60527413 0.0000000125 0.00000619 10.38131994 1.480248412 1.480248412 1
220 20.55612849 0.000000000104 0.00000039 14.90007122 1.439765255 1.439765255 1
221 3.828560252 0.002424285 0.013569984 -1.916307699 1.472119483 1.472119483 1
222 10.97761516 0.000000136 0.0000222 8.052832823 1.518735676 1.518735676 1
223 7.223168655 0.0000106 0.000181098 3.575281525 1.462096382 1.462096382 1
224 8.856700446 0.00000132 0.0000475 5.719022371 1.512573013 1.512573013 1
225 8.136727525 0.00000319 0.0000826 4.814277911 1.467472046 1.467472046 1
226 8.327264523 0.00000258 0.000134588 5.092067144 1.466004999 1.466004999 1
227 3.227731699 0.007295404 0.029311202 -3.022381083 1.474452408 1.474452408 1
228 6.696966991 0.0000226 0.000540491 2.869194342 1.518616776 1.518616776 1
229 3.436982889 0.004932147 0.014935202 -2.731810563 1.42097645 1.42097645 1
230 8.62747067 0.00000179 0.000106929 5.465029698 1.556528984 1.556528984 1
231 5.056118713 0.000286287 0.003040948 0.262536206 1.468259429 1.468259429 1
232 5.957365232 0.0000678 0.001122961 1.74158754 1.423092778 1.423092778 1
233 7.183601381 0.0000114 0.000343871 3.569359508 1.484593545 1.484593545 1
234 6.76930519 0.00002 0.000275509 2.919119461 1.421504522 1.421504522 1
235 5.023701341 0.000302143 0.003156934 0.207244146 1.433771083 1.433771083 1
236 6.962565132 0.0000152 0.000230098 3.201931954 1.585669396 1.585669396 1
237 6.983966017 0.0000148 0.000225351 3.232936444 1.431528005 1.431528005 1
238 18.50468762 0.000000000353 0.000000594 13.79815085 1.412899731 1.412899731 1
239 6.836518154 0.0000186 0.000474473 3.073310213 1.483644766 1.483644766 1
240 11.79647986 0.0000000594 0.0000073 8.863726458 1.424859454 1.424859454 1
表4.b4
      探針序列 探針位置
偵測到之環 60 mer Chr
121 sHC TTTACTGGTGTAGATATGATCTTAGTACTCGACTATGTCTGGATTAAAAAATCTTTGTGA 2
122 mHC AATATATTTCTAAAATATGTAAATATATTCGAATGCTGGAAACCAATGAAAATATTGAAA X
123 mHC CTTAATCAATTGGAGTTTAACCTTTGGTTCGATAGACGATGTGAACAAATGGAATGAACT 1
124 sHC GAAAAAAAATAAAGAGGAAATGAAATATTCGAGACCAGTCTTGAAACCCTATGTCTACTA 3
125 sHC AATAGATATACAACTGGTTATTGCAGCATCGAACTCCTGACCTCAGGCAGTCACCTTCTT 5
126 sHC ATGAAAGGAAAAATTGATAAATTTTTCATCGAACAGTAATTCTGAAATTACTGTCTTATA 8
127 mHC AAATATTCTTAAACCAAATATTTACCTATCGACTAAAGTTTCTCTATTACACTATTTCAT 4
128 mHC GTATCACCCCTGGCCATTACATTATCCATCGACCTCAATTCTAAACAAGTGCTTCTTATT 1
129 sHC ACTACAAATTTTATATGCTTACTGAATATCGATAAATCAATTGGCTAAGTAAGTGATTGA 1
130 sHC TCAGTTCTAGGAAAATTAAGTTACATCTTCGAGGTTCCAGAGACTAGACCTTGAAATAGT 1
131 mHC AAATGTGTGTGAGGGGAGAAAGCTTTGCTCGATAGACTATTAATTAAAAAATAAACTTTT 12
132 mHC AAATGTGTGTGAGGGGAGAAAGCTTTGCTCGAAAGCAAACTGTCAGCCTTTCTGGGGGAA 12
133 sHC CATTTTTACAAGGAAAGGACTTTACTCTTCGAATCTCATTTGTTTTCTTAGCTGAGAAAA 2
134 mHC AGATTTTTTTTTTTTAAAATGATTTCAATCGAATTCTATTATAAACATGAAAGTGTCTGT 2
135 mHC AATTTTGTGTTACTATTCTCCATCCTAATCGATTTCTCTTTTTCCATTATCCCTCATCCA 4
136 sHC CATTCTTTTCGTTTGAATTTGTCTTTCCTCGAGGAGCTTATTTTAAGTCTTTTTACTGAG 6
137 mHC GGTATTTCTTTTATGTATGATATATTCTTCGAACATGTTTTAGTGATTTATATTCACTCA 6
138 sHC CCTAATTTCTCTGAGTACAACTTCCTTATCGAACTCCTGACCTCAGGTTTTCTACCCGCC 8
139 mHC CACACTTGAGCTCATTGTAAACCAAAGCTCGAGAGCGGTCCCGTGGGGGCGGTGTTACTC X
140 sHC GGAGGGGTGATCACTTAAGGTCAGGAGTTCGAACTCCTGGGCCCAAGCAGTCTTTCCACC 6
141 mHC CCTCAGCATTCCATTCCAATCCTTTCTCTCGAACAGAGAACCTACTCAAATCCTGTGCAA Y
142 sHC TCATAAAATAATAATTAACAAACATACATCGAAAATATTTGACATAGTTGATCACTTCCT 2
143 sHC AATTGTTCATTGTGGATATTTCAGCCCATCGAAGAAAATGCTGAAGAATATCTTAATGAC 5
144 sHC AAAGATACAATAATTCTAAATTAAAGCTTCGACTTTAACTATGATTATATCATTGCACAA 5
145 sHC AATTGTTCATTGTGGATATTTCAGCCCATCGATCTTAACATTCAAAATCAAAACCTTGAC 5
146 mHC TAAACACATTTTTAAAAAAGATACATGATCGACGTATATTCAGTCCAAAAAAAAAAAAAA 8
147 sHC AATCTCTATCATGATATAAATTTATAAGTCGAAAAACAAAAATAATAAATGCAATATTGA 12
148 mHC GGGCGCGGGTCTGCGGAGCCCCCAGGGCTCGAAACCTGTCTGGCCAACATGGCAAAACTC 2
149 mHC GCCCCAGGTGTGTTGTGTTTGTTTCATGTCGACTGATTGATCAATTTAGTCCTTCTTGAG 16
150 mHC CCTCAGCATTCCATTCCAATCCTTTCTCTCGAGTTCAGGAAATTCTCTTCTATTCCCAGT Y
151 mHC CTTAATCAATTGGAGTTTAACCTTTGGTTCGATTTATAACAAAAATAAACACTGTAGAAA 1
152 mHC GCCCCAGGTGTGTTGTGTTTGTTTCATGTCGAAACATTACTCATCCACCAACACCTTGGC 16
153 sHC TTTCTTGTATTTCATTATGTACATCTATTCGAGTTTTATATAAATTCAATCATATTTAAG 6
154 sHC AAGTTACAGGCGTCACCAAAGTTTAGGCTCGAGGCCGCAGTAAGCTGTGTTCACACCACT 9
155 mHC CCTTTTATCCCTGAGCCATTGAAATGGTTCGAAACCATCCTTACCCCTATTTAATGTAGT X
156 mHC ATTTGAGAAATAAAATGTTTCATTTTTATCGAAAACTATTAATTTTTAAAAATGTAAGTG 10
157 sHC CATTCTTTTCGTTTGAATTTGTCTTTCCTCGAGATGTACTTTAGATGTAAAATACATACC 6
158 sHC CAGTAATCCTAGAAAGACAACTGATACATCGATTCTCGGAGGGTAACATTAAATGCCAAT 8
159 mHC CTCCATAGCTGATGATAGGAACTGTTTATCGATGTTAGACTGAATAAAGAAAATGTAGCA 9
160 sHC AATGTAAAGGAGTGAATCATTCAGATATTCGAAAAAGATATATAAAGCAATAATTAACAG X
161 sHC AAGGAACTTTTGGAGACATTTAGTGATATCGAAGCATTACTTTTGCCTTTCAACCCATGC X
162 sHC TTCTTTTGTGCTAAAATATAGAAAGTAATCGACTAATCAGGTAGGTCTGGGTACTTTCAC 10
163 sHC TGTCTTGAGGCTTACTAGTGCACTCCCGTCGAGAAATCTTCACTTTTCTATGCAAGCACA 7
164 mHC ATCACTGTGTGCACAGGTGTGTGTGCTTTCGATTGGGCAGTTTCACTTCCATGTTCCAGA 6
165 mHC AAGAGAGGTGGGGACATTGTGAACTGAATCGAACAAGTGAGGGAAGTTCTGGGAAATCAG 8
166 sHC AAGTTCTAAGGAAGAAAAGAGTCTCCTTTCGAGTATTCTGTTCAACATTGTATCCTAAGT 11
167 mHC ACAGGTATTAGGGTGTTTATTTTGCTTCTCGAATTATATATCAAAGACCATAAGTTCTCA 12
168 sHC AATCTTTTTTCATAAAATGAAGAATAACTCGATGAGTTTCTGTATTCAGGATTGGTGTTT 12
169 mHC TTAAAGAAAAGCCTATAATTTGAAGAATTCGATTTTAGTATGACAACTAAGAACATAAAA 15
170 mHC CCTGTGCAAAGTATGACTCTAGTAACATTCGAGATATGACTATCTTTCAGAGAAGCACTA X
171 mHC CATATTCCTAAAATAAATTATACATGCTTCGATAAAAATGTACTTCAAAAATTGGATTGG 5
172 mHC AGGCAGATAACAAAACCATCCCACCGCATCGATCTTTTCATGACGCGTTTTCCTTCTGTG 6
173 mHC TATAAAAATAAAAATAATATATGAATTATCGAGTCCTCAATAAATATTTGCCAAAAACCA 4
174 mHC AAGAGAGGTGGGGACATTGTGAACTGAATCGAATAGGATATACCAATGTGGACTTGTCTG 8
175 mHC GTATCACCCCTGGCCATTACATTATCCATCGAACCAACTTCAAATAAGGCAAACACCAAG 1
176 mHC GTATCACCCCTGGCCATTACATTATCCATCGAAAGTTTAAACTGCCAGCCAAACTTTGTG 1
177 sHC GGCGGATCACCTGATGTCAGTCAGGAGTTCGATCACATTGATTTAAATTACAGGGACCTT 12
178 mHC GTTTATCTGCTAGCTAGGATTTATATAATCGAGCATTTATATACAATAGCAAATCATCCA 13
179 mHC AATTTGTTCGTTAGGTTAAATTAACATATCGATTCACTAGAATTTTCCTATTTGATGATT 15
180 mHC GCCCCAGGTGTGTTGTGTTTGTTTCATGTCGAAACATTACTCATCCACCAACACCTTGGC 16
181 mHC CAACTTCACAACATGAAGTCATTCAATATCGATTTTAGGTTCCTTTCCCCAGTCAGTCCA 2
182 mHC CTCCATAGCTGATGATAGGAACTGTTTATCGAGTTGTATTGTTTCTATTTTCCATTCAGT 9
183 sHC AGGCAGGTGAATCACTTGAGATCAGAGTTCGACACAGAAAAAGAGAAATATGAGATTATG X
184 sHC TTCGTCTATTGAGAGTTTTTGACATGAATCGACTAAACAAGCAAGAAAAATTAAAAACAA X
185 mHC ATTCACATAAAAAACTTTTTTGTGAACATCGATGAACGTGGAATATATTTCAATTTTTTT 3
186 mHC ACTGAAATGTTTTTTTAAATCAGTGGTGTCGAGGTGATGAAGTCTGATCTGTGTCAAGCC 6
187 mHC AATAAAGAAAAAAATCTTCTAAAATAATTCGATAACTTTCTTCCCTGAAAGGGTTAAAAA 8
188 sHC TCTAGGAGAATTCTTTACTCCAATTACTTCGAAATTAAGGAACCTCCTACTTTTTACATC 12
189 mHC AGGTAATTAAGACAAGAAAGACATTTATTCGATTTCTTTATCAGAAGAGTAAAGCAAGCA 2
190 sHC GTTCTTTAGTCTGAACCTTCCTTTCCAGTCGAGGCCGCAGTAAGCTGTGTTCACACCACT 9
191 mHC ATATGCTTTTTTTAAATTACAAAACTTATCGAAACTGGTGGATCCACCAGGTTGAAGGAG 12
192 mHC AAGAGAGGTGGGGACATTGTGAACTGAATCGAATGGAAAGGCCCTTTTTAGACAACTAAT 8
193 mHC GAGATTTTCTTAAGACGGTAATTCTTAATCGAGACTTCTTTTTATAACCAAATAATTTTA 2
194 sHC AATTATGGTAATGTGTTCTCTTCATCCTTCGAATTTAGAGATGAACACACGTTCTGCCTC 6
195 mHC TATGTTGTCAATTTAATCTCAAATTATCTCGATACCTATTATTGTTTATCTTTTTTATTA 2
196 sHC AAGGCAGGCATATCATGAGGTCAGAAGATCGATCTTTCTATGGTGCATTTTCAGAGATGT 3
197 mHC AAGAGAGGTGGGGACATTGTGAACTGAATCGATGCCAAACAGCTGGAACTCTCAAATCAC 8
198 mHC ATTTTTAATTATTAAAAAATAATGTTTTTCGATTACTTTACTGGATTGTCTCACAGAACT 2
199 mHC GTATCACCCCTGGCCATTACATTATCCATCGAGGTCATCAGAGGTCCACAACTTTAGGGA 1
200 sHC ATCTATTTGGCTTATGAATTACCCAGTATCGATGAATCAACATTTTCCAAAATAATACAT 12
201 sHC CATTTTTACAAGGAAAGGACTTTACTCTTCGACATTACTTTTTGTTTTCATTCCTACACT 2
202 mHC TTTATATTTTTATTTTCTATAACATACCTCGATTTTTACAAGAAATTTAAAAATTAGCTT 2
203 sHC GGCCGGCAGATCACTTCAGGTCAAGAGTTCGATGATGATATAGGCATTAAAACATGAGTT 21
204 mHC TAAAACTATTTTAAATGTTTTTAAAGTATCGAAAACTAAATCTCTAATCTCTAACCTTTC 4
205 sHC CATTCTTTTCGTTTGAATTTGTCTTTCCTCGAGGAGCTTATTTTAAGTCTTTTTACTGAG 6
206 sHC CTAACATAAAATAAACCTCTTACAAATTTCGATGATGTTCAAAAATAGTAGATTAAACCA 6
207 sHC TCTTGTCTGAAATCATCAAGGCAGTACCTCGAGTCTCCTTTTGGATATTTTCTTCCAAAA X
208 sHC TTTACTGGTGTAGATATGATCTTAGTACTCGAGTGGTAATGTACCAATCATTCATTGATT 2
209 sHC TGAAAATATTGTACTTATATTAAATTAATCGAACTCCTAGTCTCAAGTGATCCACCTGTC 22
210 sHC CTCTGCATTTATTGTAAACTATCTTAAATCGAAGTTGGTAAGTTGGTTTCTAAACATTTT 8
211 sHC GGTGGGTAGATCACCTGAGGTCAGGAGTTCGAACTCCTAACCTCAGGTGATCTACCCACT 1
212 mHC ATTTGAGAAATAAAATGTTTCATTTTTATCGATCATATATATATATATATATATATATAC 10
213 sHC AATTCTTCCCTAAGGATATTTATTAACTTCGATAACTACAAAGAAACTAAAAACGCTACC 11
214 mHC TTATTTGAAAACAACGTCAAGAGAAGGCTCGATGGGAGGCATGACAGAAATTATATTAAT 5
215 sHC GGCCAAGTCTTTAGAGAGTTGTGATCACTCGAAGGTATTAAAATCTTCAACTAAAATACT 17
216 mHC TTTCTTGTATTTCATTATGTACATCTATTCGATTATAAGCTAACATTGAAGGTATTCGTA 6
217 mHC GAGGCGGGTGATTCACAAGGTCAGATGTTCGAAATTGTGTAAATAAGCATTTGCAGCCCT 6
218 mHC CTGCAGGTGTGTGCATTAAGGAGCAACTTCGAGACAATCCTGGTCAACATGGTGAAACCC 1
219 mHC GTATCACCCCTGGCCATTACATTATCCATCGATAAGGATTCTATAGAGTCAGATTCTCTA 1
220 sHC GGCAGGTGGATCTCTTGAGGTCAGAAGTTCGAGTCACCAAATGAGGAATCTAAAATAGCC 1
221 mHC AAATGTGTGTGAGGGGAGAAAGCTTTGCTCGATTTAATTGCAGTGGTCATATTAGCTTCC 12
222 mHC TGTATACCAAATAAATCAAATAAATAAATCGATTGAGTAGGTTTTATGTTGATTGGTTGG 15
223 sHC TAATCTCCTCAAGTATACCATAAATTATTCGACCAGGAGTAAACATAGTTAAATGAATAA 18
224 sHC CTATATTGTAGCTCTATTTTCTCTAAATTCGACAACTTTACTTCTATGTATTATGATCCT 2
225 sHC GGCCGGCAGATCACTTCAGGTCAAGAGTTCGACTTCCTTAAAGTTTCATTTTGATGAAGT 21
226 mHC TTCAATTGTACTGTTAATATTTTATTTCTCGAATAAATAATCCTCTTCTTTTCCTCTTTC 5
227 mHC CACACTTGAGCTCATTGTAAACCAAAGCTCGAGAGCGGTCCCGTGGGGGCGGTGTTACTC X
228 mHC CTGCAGGTGTGTGCATTAAGGAGCAACTTCGAAAAGTCCAGAATGAACTCCAAAGATTGA 1
229 sHC GAAGCAGAGATGTTTTCAGTTACAAAGCTCGACATTTTGAATATGTGGGATCCAAATCTG 17
230 mHC TGTAACAGATCCTTAAAAAAAAATAAAATCGAATTATAGCTCTTTATAGGAAATGTTCAC 4
231 mHC AAGAGAGGTGGGGACATTGTGAACTGAATCGATTGCTGTCCATGTCCATTGGCACTTGGC 8
232 mHC TTTTTAAAGAAGGTTTGTATCATATTTCTCGATATTATTCTATCAGTCCTGCAGTCCTGT 19
233 mHC GCCCACTAAATAGTAATATTAGGATCTATCGAAATTTAACTTGTAACTCAAGTAAAATTG 9
234 sHC ATTACCCATATACATATCGTATATAAAATCGAAACCTCTATTTTCAGGTAGCCATTATGA 4
235 mHC AAGAGAGGTGGGGACATTGTGAACTGAATCGACCCCAGGGTAAAAGTTAGCTATTCTAAA 8
236 sHC AACTAAAATCTCCCACAAGGGAAAACCTTCGAGGCCGCAGTAAGCTGTGTTCACACCACT 9
237 sHC CGTCTTTCCTTTAGGGCTTCATTTAACTTCGATTGTTCTTTTACTATTATTCACTCTTGG X
238 sHC GGCTGGCAGATCACTTGAGGCCAGTAGTTCGAATGAGGAATACATGTTTATTTGAATAGC 13
239 mHC AATATACATAAAAGTTACTTTTTTTTTTTCGAAACTTATGTCACAGAAAAAAAGCAGTAA 14
240 sHC CTATTTCAACAAAAAAACTCATTTAAAATCGAAGTATGGTTTATATTATGACATTATGTC 2
表4.b5
   探針位置 4 kb 序列位置
起點 1 終點 1 起點 2 終點 2 Chr 起點 1 終點 1 起點 2 終點 2
121 56316547 56316578 56347853 56347884 2 56312577 56316578 56343883 56347884
122 103111808 103111839 103163519 103163550 X 103107838 103111839 103159549 103163550
123 229797491 229797522 229849427 229849458 1 229793521 229797522 229849427 229853428
124 40983293 40983324 41025836 41025867 3 40979323 40983324 41025836 41029837
125 56055669 56055700 56069488 56069519 5 56051699 56055700 56069488 56073489
126 22342734 22342765 22373651 22373682 8 22338764 22342765 22369681 22373682
127 88282468 88282499 88335985 88336016 4 88278498 88282499 88335985 88339986
128 110164010 110164041 110248816 110248847 1 110160040 110164041 110244846 110248847
129 186762629 186762660 186824303 186824334 1 186762629 186766630 186820333 186824334
130 210312443 210312474 210344738 210344769 1 210312443 210316444 210344738 210348739
131 13269291 13269322 13314367 13314398 12 13269291 13273292 13310397 13314398
132 13314367 13314398 13342225 13342256 12 13310397 13314398 13342225 13346226
133 11479893 11479924 11535514 11535545 2 11479893 11483894 11531544 11535545
134 5932311 5932342 5980282 5980313 2 5928341 5932342 5976312 5980313
135 37859966 37859997 37914414 37914445 4 37859966 37863967 37914414 37918415
136 134212503 134212534 134271335 134271366 6 134212503 134216504 134267365 134271366
137 84755923 84755954 84786605 84786636 6 84751953 84755954 84782635 84786636
138 119857282 119857313 119882110 119882141 8 119853312 119857313 119882110 119886111
139 115878688 115878719 115945548 115945579 X 115878688 115882689 115941578 115945579
140 89493632 89493663 89550722 89550753 6 89493632 89497633 89546752 89550753
141 11009126 11009157 11075743 11075774 Y 11005156 11009157 11075743 11079744
142 38155445 38155476 38179203 38179234 2 38151475 38155476 38179203 38183204
143 26963456 26963487 26999889 26999920 5 26959486 26963487 26999889 27003890
144 38611059 38611090 38683282 38683313 5 38607089 38611090 38679312 38683313
145 26963456 26963487 27004713 27004744 5 26959486 26963487 27000743 27004744
146 29147602 29147633 29216944 29216975 8 29143632 29147633 29216944 29220945
147 82575759 82575790 82624217 82624248 12 82571789 82575790 82624217 82628218
148 27495025 27495056 27545211 27545242 2 27491055 27495056 27541241 27545242
149 11990167 11990198 12005204 12005235 16 11986197 11990198 12005204 12009205
150 11009126 11009157 11075712 11075743 Y 11005156 11009157 11071742 11075743
151 229797491 229797522 229859020 229859051 1 229793521 229797522 229859020 229863021
152 11990167 11990198 12009229 12009260 16 11986197 11990198 12005259 12009260
153 73669509 73669540 73690117 73690148 6 73669509 73673510 73686147 73690148
154 33299656 33299687 33317596 33317627 9 33299656 33303657 33317596 33321597
155 103336904 103336935 103357970 103358001 X 103336904 103340905 103357970 103361971
156 89864618 89864649 89926184 89926215 10 89860648 89864649 89922214 89926215
157 134271335 134271366 134289631 134289662 6 134267365 134271366 134285661 134289662
158 21022651 21022682 21074365 21074396 8 21022651 21026652 21074365 21078366
159 94791100 94791131 94822711 94822742 9 94791100 94795101 94818741 94822742
160 118719838 118719869 118775165 118775196 X 118719838 118723839 118771195 118775196
161 134227323 134227354 134251763 134251794 X 134227323 134231324 134251763 134255764
162 110775235 110775266 110797638 110797669 10 110775235 110779236 110797638 110801639
163 22396847 22396878 22452771 22452802 7 22392877 22396878 22452771 22456772
164 37604858 37604889 37631492 37631523 6 37600888 37604889 37627522 37631523
165 97888636 97888667 97937368 97937399 8 97884666 97888667 97933398 97937399
166 102000275 102000306 102027848 102027879 11 101996305 102000306 102023878 102027879
167 54591576 54591607 54623187 54623218 12 54587606 54591607 54623187 54627188
168 46922957 46922988 46952555 46952586 12 46922957 46926958 46952555 46956556
169 65512147 65512178 65573794 65573825 15 65512147 65516148 65573794 65577795
170 11366661 11366692 11459265 11459296 X 11366661 11370662 11459265 11463266
171 7555641 7555672 7606244 7606275 5 7555641 7559642 7606244 7610245
172 45815741 45815772 45845191 45845222 6 45815741 45819742 45845191 45849192
173 21879694 21879725 21965631 21965662 4 21879694 21883695 21965631 21969632
174 97888636 97888667 97933550 97933581 8 97884666 97888667 97933550 97937551
175 110164010 110164041 110187380 110187411 1 110160040 110164041 110183410 110187411
176 110164010 110164041 110248847 110248878 1 110160040 110164041 110248847 110252848
177 16574208 16574239 16637234 16637265 12 16574208 16578209 16633264 16637265
178 53036652 53036683 53050162 53050193 13 53032682 53036683 53046192 53050193
179 22835609 22835640 22893089 22893120 15 22831639 22835640 22889119 22893120
180 11990167 11990198 12009229 12009260 16 11986197 11990198 12005259 12009260
181 169105039 169105070 169146919 169146950 2 169101069 169105070 169146919 169150920
182 94822711 94822742 94896134 94896165 9 94818741 94822742 94892164 94896165
183 1174946 1174977 1242344 1242375 X 1174946 1178947 1238374 1242375
184 5600895 5600926 5621246 5621277 X 5596925 5600926 5621246 5625247
185 106249641 106249672 106313861 106313892 3 106245671 106249672 106313861 106317862
186 157307294 157307325 157340005 157340036 6 157307294 157311295 157336035 157340036
187 113381107 113381138 113436243 113436274 8 113381107 113385108 113436243 113440244
188 26021026 26021057 26034684 26034715 12 26017056 26021057 26034684 26038685
189 129205308 129205339 129233271 129233302 2 129205308 129209309 129229301 129233302
190 33260613 33260644 33317596 33317627 9 33256643 33260644 33317596 33321597
191 96219857 96219888 96241318 96241349 12 96219857 96223858 96237348 96241349
192 97888636 97888667 97946210 97946241 8 97884666 97888667 97942240 97946241
193 209662023 209662054 209738615 209738646 2 209658053 209662054 209734645 209738646
194 61648546 61648577 61699874 61699905 6 61648546 61652547 61695904 61699905
195 21342478 21342509 21390529 21390560 2 21342478 21346479 21386559 21390560
196 78745074 78745105 78759779 78759810 3 78741104 78745105 78755809 78759810
197 97811124 97811155 97888636 97888667 8 97811124 97815125 97884666 97888667
198 195589030 195589061 195630259 195630290 2 195585060 195589061 195630259 195634260
199 110164010 110164041 110272003 110272034 1 110160040 110164041 110268033 110272034
200 83896006 83896037 83957569 83957600 12 83892036 83896037 83953599 83957600
201 11504797 11504828 11535514 11535545 2 11504797 11508798 11531544 11535545
202 20297935 20297966 20328998 20329029 2 20297935 20301936 20328998 20332999
203 17392864 17392895 17439402 17439433 21 17388894 17392895 17435432 17439433
204 153700318 153700349 153769067 153769098 4 153696348 153700349 153765097 153769098
205 134212503 134212534 134271335 134271366 6 134212503 134216504 134267365 134271366
206 162152986 162153017 162211718 162211749 6 162152986 162156987 162207748 162211749
207 37321219 37321250 37333766 37333797 X 37317249 37321250 37333766 37337767
208 56316547 56316578 56394093 56394124 2 56312577 56316578 56390123 56394124
209 20774362 20774393 20816159 20816190 22 20770392 20774393 20816159 20820160
210 9126258 9126289 9220259 9220290 8 9122288 9126289 9220259 9224260
211 211433313 211433344 211470751 211470782 1 211433313 211437314 211466781 211470782
212 89827266 89827297 89864618 89864649 10 89827266 89831267 89860648 89864649
213 75864693 75864724 75943194 75943225 11 75860723 75864724 75939224 75943225
214 167858519 167858550 167921706 167921737 5 167854549 167858550 167921706 167925707
215 16800716 16800747 16884815 16884846 17 16796746 16800747 16880845 16884846
216 73690117 73690148 73749995 73750026 6 73686147 73690148 73746025 73750026
217 151449133 151449164 151538545 151538576 6 151445163 151449164 151534575 151538576
218 48539737 48539768 48603267 48603298 1 48535767 48539768 48603267 48607268
219 110141802 110141833 110164010 110164041 1 110141802 110145803 110160040 110164041
220 223787115 223787146 223834661 223834692 1 223787115 223791116 223834661 223838662
221 13270343 13270374 13314367 13314398 12 13270343 13274344 13310397 13314398
222 22839534 22839565 22886396 22886427 15 22839534 22843535 22882426 22886427
223 12837148 12837179 12853029 12853060 18 12837148 12841149 12849059 12853060
224 78765418 78765449 78804372 78804403 2 78761448 78765449 78804372 78808373
225 17392864 17392895 17435717 17435748 21 17388894 17392895 17431747 17435748
226 93565548 93565579 93583739 93583770 5 93561578 93565579 93579769 93583770
227 115872740 115872771 115945548 115945579 X 115872740 115876741 115941578 115945579
228 48539737 48539768 48618771 48618802 1 48535767 48539768 48614801 48618802
229 36192362 36192393 36216401 36216432 17 36192362 36196363 36216401 36220402
230 175635137 175635168 175665390 175665421 4 175635137 175639138 175661420 175665421
231 97888636 97888667 97913281 97913312 8 97884666 97888667 97909311 97913312
232 46459835 46459866 46481483 46481514 19 46459835 46463836 46477513 46481514
233 28339600 28339631 28379485 28379516 9 28335630 28339631 28375515 28379516
234 15556941 15556972 15665131 15665162 4 15556941 15560942 15665131 15669132
235 97888636 97888667 97955459 97955490 8 97884666 97888667 97955459 97959460
236 33260644 33260675 33317596 33317627 9 33260644 33264645 33317596 33321597
237 101078729 101078760 101109398 101109429 X 101074759 101078760 101105428 101109429
238 45792577 45792608 45859224 45859255 13 45792577 45796578 45859224 45863225
239 73418771 73418802 73454993 73455024 14 73418771 73422772 73454993 73458994
240 164435438 164435469 164496617 164496648 2 164431468 164435469 164492647 164496648
表4.b6
   探針 PCR- 引子 1_ID PCR_ 引子 1
121 ORF144_2_56308065_56316578_56344324_56347884_FF OBD159_2701 GTCTGAGGACCCACACAAAGGAAC
122 ORF144_X_103107164_103111839_103158530_103163550_FF OBD159_2705 GGGATGCCTGGGACATAAGTCAGATG
123 ORF146_1_229796281_229797522_229849427_229855718_FR OBD159_2709 CACAGCAACAAAAGCAACCTGGTGTC
124 ORF148_3_40973608_40983324_41025836_41032545_FR OBD159_2713 GGAGAATACCTACAGGCAGCCCAGAA
125 ORF148_5_56051850_56055700_56069488_56074299_FR OBD159_2717 CTGAGTGGAGTAGCGTGGGTGAG
126 ORF148_8_22339630_22342765_22370928_22373682_FF OBD159_2721 GGTGGCTTTGGGTTTGGTGATTACTT
127 ORF149_4_88278877_88282499_88335985_88339586_FR OBD159_2725 CTTCCACAATGAGAACACAGCCCTTT
128 ORF15_1_110155952_110164041_110243262_110248847_FF OBD159_2729 AGAGATGCCCTTCCTGACTGCCC
129 ORF15_1_186762629_186769807_186806428_186824334_RF OBD159_2733 GTGGGCTTTGGAGTTGGACCGAC
130 ORF15_1_210312443_210322312_210344738_210348320_RR OBD159_2737 CCACAGACATTGGAGGTTGAGTT
131 ORF15_12_13269291_13270343_13311794_13314398_RF OBD159_2741 GCGATACTTACGAAAATGAAGCCAGG
132 ORF15_12_13311794_13314398_13342225_13351549_FR OBD159_2745 TAGGGTGGGCACAGAAGGGTGGT
133 ORF15_2_11479893_11482767_11532162_11535545_RF OBD159_2749 TTTGAAGGTCATCTCAGGAAGGGC
134 ORF15_2_5924503_5932342_5965887_5980313_FF OBD159_2753 GGTCTCCAGGTCTCCTTAGTCTCAGT
135 ORF15_4_37859966_37862832_37914414_37919908_RR OBD159_2757 GAAAATAACAGTTCTCAGGAAGGCAT
136 ORF15_6_134212503_134214388_134270140_134271366_RF OBD159_2761 GGCAGGAGAATCACTTGAACCTA
137 ORF15_6_84752549_84755954_84775145_84786636_FF OBD159_2765 TAAGACATTGTTTAGCAACTTCCAA
138 ORF15_8_119855069_119857313_119882110_119888009_FR OBD159_2769 CTTCAGAACTTTGTGACCTAAGGCAAT
139 ORF15_X_115878688_115881423_115936015_115945579_RF OBD159_2773 CAGGAATCATTTGACACAATCCCC
140 ORF150_6_89493632_89495030_89546588_89550753_RF OBD159_2777 GGGCTGCTGGATACTGGTTAGTC
141 ORF150_Y_11007821_11009157_11075743_11080103_FR OBD159_2781 CCACTACAATCCACTTCCACTCCACT
142 ORF152_2_38148629_38155476_38179203_38180978_FR OBD159_2785 CCCGCCCACATCCTGAGAATCCT
143 ORF152_5_26952527_26963487_26999889_27004744_FR OBD159_2789 GGCTCTAATCCCCTTTGAGGTGCGAA
144 ORF152_5_38608515_38611090_38682143_38683313_FF OBD159_2793 AACTGGAGTCTTTCTATGGCTTGAAT
145 ORF153_5_26952527_26963487_26999889_27004744_FF OBD159_2797 GCTCTAATCCCCTTTGAGGTGCGAAA
146 ORF153_8_29144477_29147633_29216944_29221322_FR OBD159_2801 TTCGTGCTCATACATAAGCCTCTGGC
147 ORF154_12_82572942_82575790_82624217_82631901_FR OBD159_2805 GGCAGATAAAGAAAATAGATGTCTCC
148 ORF155_2_27492451_27495056_27542894_27545242_FF OBD159_2809 TTTTCTCTACGCCCTCCCGCCCC
149 ORF156_16_11987495_11990198_12005204_12009260_FR OBD159_2813 TCAGTATGGCGGATTGGTGGCGG
150 ORF156_Y_11007821_11009157_11057559_11075743_FF OBD159_2817 TCCACTCCATTCCATTCCACTGC
151 ORF157_1_229796281_229797522_229859020_229862315_FR OBD159_2821 CAGCACCAGCAACCACAGCAACA
152 ORF158_16_11987495_11990198_12005204_12009260_FF OBD159_2825 AGTATGGCGGATTGGTGGCGGGC
153 ORF158_6_73669509_73673385_73688989_73690148_RF OBD159_2829 TCAGTGTTTGCTTTTCCCTTGAAT
154 ORF158_9_33299656_33304064_33317596_33319558_RR OBD159_2833 GTCTGTTCCACAACCTCTTTCTG
155 ORF158_X_103336904_103343604_103357970_103363324_RR OBD159_2837 CAACCAATCCAGAACCCATACCACCA
156 ORF159_10_89863078_89864649_89921840_89926215_FF OBD159_2841 CCCACTGGAGCATAAGATGAACCAAT
157 ORF16_6_134270140_134271366_134285274_134289662_FF OBD159_2845 TGAGGCAGGAGAATCACTTGAACC
158 ORF16_8_21022651_21025530_21074365_21076495_RR OBD159_2849 CGGGAGGTTTCTGTGAGAGGTGT
159 ORF16_9_94791100_94792692_94818790_94822742_RF OBD159_2853 TCTGATTCTCTTCATTGCTCGGAAAT
160 ORF16_X_118719838_118725132_118772495_118775196_RF OBD159_2857 CCAAGAAAGTGACATTTGAGGAGAGA
161 ORF16_X_134227323_134230233_134251763_134253313_RR OBD159_2861 ATGCTCAAGAAGAAGTAATGCCAGGG
162 ORF160_10_110775235_110786527_110797638_110800058_RR OBD159_2865 TCCAGAAGCAGGAGCCAAGAACCACA
163 ORF160_7_22390272_22396878_22452771_22454987_FR OBD159_2869 AGGCTCCTGGGTTCCTATGTTCAAAT
164 ORF164_6_37603737_37604889_37629301_37631523_FF OBD159_2873 TTTGACCAGGAAACAGTGAGAGCAGT
165 ORF164_8_97885717_97888667_97935143_97937399_FF OBD159_2877 TGTTGTTGGACCTATCTGAGCAAAGG
166 ORF166_11_101998219_102000306_102025025_102027879_FF OBD159_2881 TGGCAACAGAGCAAGACTCCGTC
167 ORF166_12_54589309_54591607_54623187_54631741_FR OBD159_2885 TAACCCTCACAACCACCCAGGAG
168 ORF167_12_46922957_46926200_46952555_46954006_RR OBD159_2889 CTAAGTTCCTGTGTGTCTGTCTTGAC
169 ORF167_15_65512147_65515718_65573794_65596385_RR OBD159_2893 CAGAATCTATTACCTTGGTGAGTA
170 ORF167_X_11366661_11385597_11459265_11462297_RR OBD159_2897 CCCTTGTGAAAACTGAACACCACCCC
171 ORF168_5_7555641_7557907_7606244_7610178_RR OBD159_2901 GGAGCCTAAAGTTATGGGAATGTCAT
172 ORF168_6_45815741_45822184_45845191_45849862_RR OBD159_2905 CAAGGTGGCAGTTGGCAGTCAGAAAG
173 ORF169_4_21879694_21883839_21965631_21973272_RR OBD159_2909 GGTGAGGACACAGCGAAACCATA
174 ORF169_8_97885717_97888667_97933550_97935143_FR OBD159_2913 GGTCCTTGTTGGATGTGCTGGGC
175 ORF17_1_110155952_110164041_110184326_110187411_FF OBD159_2641 GCATAAAAGAGCCACCTGCCAGC
176 ORF17_1_110155952_110164041_110248847_110251734_FR OBD159_2917 CCCCGCATCCAGCATAAAAGAGCC
177 ORF17_12_16574208_16575957_16629200_16637265_RF OBD159_2921 AAAAGCAACCTGGGCTGGGCACG
178 ORF17_13_53034265_53036683_53047390_53050193_FF OBD159_2922 AAAAGCAACCTGGGCTGGGCACG
179 ORF17_15_22830640_22835640_22890866_22893120_FF OBD159_2923 AAAAGCAACCTGGGCTGGGCACG
180 ORF17_16_11987495_11990198_12005204_12009260_FF OBD159_2825 AGTATGGCGGATTGGTGGCGGGC
181 ORF17_2_169092304_169105070_169146919_169154561_FR OBD159_2933 GGTTGGGCAGACAGTTCCTGGGA
182 ORF17_9_94818790_94822742_94893440_94896165_FF OBD159_2937 TCATCTCAGTTGCTTTCTGCTGGAGC
183 ORF17_X_1174946_1177246_1240440_1242375_RF OBD159_2941 CGCCTGTAATCCCAGCAGTTTGG
184 ORF17_X_5594024_5600926_5621246_5623679_FR OBD159_2945 GAGACATTGGCTGTGGGTTTGTT
185 ORF170_3_106246431_106249672_106313861_106318469_FR OBD159_2949 CATCATTTCCCGCCCTTGTCTTTA
186 ORF170_6_157307294_157314514_157337743_157340036_RF OBD159_2953 GGCGGTTTGGAGGTTGGGCAGTT
187 ORF170_8_113381107_113383608_113436243_113437347_RR OBD159_2957 GCAGAACCCCTTGTAATCCCCAAATA
188 ORF171_12_26016038_26021057_26034684_26036629_FR OBD159_2961 TTTCTAAGCACTCAGGGCAATGTCTA
189 ORF172_2_129205308_129208404_129231919_129233302_RF OBD159_2965 GAGGCGAATAGGACCCAGGTAGAAGT
190 ORF172_9_33252746_33260644_33317596_33319558_FR OBD159_2969 GGTTGCTGACCTCATCTGTCTTT
191 ORF173_12_96219857_96223649_96237099_96241349_RF OBD159_2973 GCCTGTGGCTTTATGCCTGGGTC
192 ORF173_8_97885717_97888667_97943674_97946241_FF OBD159_2977 TGTTGTTGGACCTATCTGAGCAAAGG
193 ORF176_2_209659511_209662054_209735707_209738646_FF OBD159_2981 GGTATTGCCAGCCACAGCGTTTGATA
194 ORF176_6_61648546_61654260_61698546_61699905_RF OBD159_2985 GCTCAGCCCTCACTGCCCAACAT
195 ORF177_2_21342478_21344227_21387178_21390560_RF OBD159_2989 ACTGAAGTATTACAGGAGTGATGGG
196 ORF177_3_78739183_78745105_78757303_78759810_FF OBD159_2993 TCAATCCCACCTGAACCCTAATGAAT
197 ORF177_8_97811124_97813316_97885717_97888667_RF OBD159_2997 GGTCCTTGTTGGATGTGCTGGGC
198 ORF179_2_195583610_195589061_195630259_195633750_FR OBD159_3001 GGCTATTGGAATGGCTGAAGTGTGAA
199 ORF18_1_110155952_110164041_110268937_110272034_FF OBD159_3005 AGAGATGCCCTTCCTGACTGCCC
200 ORF18_12_83891421_83896037_83954032_83957600_FF OBD159_3009 TGTGACGGTGCCTGCTTCCCCTT
201 ORF18_2_11504797_11509096_11532162_11535545_RF OBD159_3013 CTTTTGAAGGTCATCTCAGGAAGGGC
202 ORF18_2_20297935_20303337_20328998_20331608_RR OBD159_3017 GCTCTCACATTTATTTTATGCCAGTC
203 ORF18_21_17391129_17392895_17437778_17439433_FF OBD159_2257 CGCCTGTAATCCCACCACTTTGG
204 ORF18_4_153693586_153700349_153764783_153769098_FF OBD159_3021 CCCAAACGCTTTCCACCAGGTCC
205 ORF18_6_134212503_134214388_134270140_134271366_RF OBD159_2761 GGCAGGAGAATCACTTGAACCTA
206 ORF18_6_162152986_162154134_162206360_162211749_RF OBD159_3025 CTCCCACATTCTTTGTTCATCTTCAA
207 ORF18_X_37313041_37321250_37333766_37337668_FR OBD159_3029 CCTATCTGGCTGTGACACCTGCTGAT
208 ORF180_2_56308065_56316578_56390760_56394124_FF OBD159_3033 GTCTGAGGACCCACACAAAGGAACTT
209 ORF183_22_20770086_20774393_20816159_20817209_FR OBD159_3037 GTTCCATTGTTGGGAGAGTTGAC
210 ORF183_8_9123942_9126289_9220259_9225462_FR OBD159_3041 CAGCAACCTCTTCTGGTCTTTGA
211 ORF184_1_211433313_211435632_211464001_211470782_RF OBD159_3045 ATCCCAGCATTTTGGAAGACTGAG
212 ORF184_10_89827266_89829504_89863078_89864649_RF OBD159_3049 CCCACTGGAGCATAAGATGAACCAAT
213 ORF184_11_75861382_75864724_75932505_75943225_FF OBD159_3053 GCCTCTGAAGAAGCACTGCCAGG
214 ORF184_5_167857386_167858550_167921706_167923030_FR OBD159_3057 GGTTGGTAGTGGCTTCTTTCCTGGCA
215 ORF185_17_16799136_16800747_16881471_16884846_FF OBD159_3061 ATGGAGCGAGGTATGGTGGCATTGC
216 ORF186_6_73688989_73690148_73742434_73750026_FF OBD159_3065 TCAGTGTTTGCTTTTCCCTTGAAT
217 ORF187_6_151443530_151449164_151537463_151538576_FF OBD159_3069 CGCCTGTAACCCCAGCATTTTGG
218 ORF189_1_48532003_48539768_48603267_48618802_FR OBD159_3073 AAGGTTCTTGCCACATTCCGCCC
219 ORF19_1_110141802_110145853_110155952_110164041_RF OBD159_2281 GCATAAAAGAGCCACCTGCCAGC
220 ORF19_1_223787115_223791224_223834661_223838535_RR OBD159_3077 CAAAGTGCTGAAGTTATGGGCGT
221 ORF19_12_13270343_13274324_13311794_13314398_RF OBD159_3081 TAGGGTGGGCACAGAAGGGTGGT
222 ORF19_15_22839534_22840551_22879924_22886427_RF OBD159_3085 GCAGATAGCAGGAGACCCCTACTG
223 ORF19_18_12837148_12839042_12851275_12853060_RF OBD159_3089 TAAAAGCCATCCCTGCCTCCTTGGG
224 ORF19_2_78763526_78765449_78804372_78809080_FR OBD159_3093 GATTTCTCAGTTTACATAGTTCAAA
225 ORF19_21_17391129_17392895_17434190_17435748_FF OBD159_2253 CGCCTGTAATCCCACCACTTTGG
226 ORF19_5_93562856_93565579_93582366_93583770_FF OBD159_3097 ATGCCCAGTCATAGGTGATAAGATTA
227 ORF19_X_115872740_115875445_115936015_115945579_RF OBD159_3101 CAGGAATCATTTGACACAATCCCC
228 ORF190_1_48532003_48539768_48603267_48618802_FF OBD159_3105 TTCTTGCCACATTCCGCCCCAGC
229 ORF190_17_36192362_36195269_36216401_36221747_RR OBD159_3109 CCCTTCTAATGTCCATAGGCTAC
230 ORF190_4_175635137_175638077_175657671_175665421_RF OBD159_3113 CCGAGGGATAGGGATTCTGTTTTGTT
231 ORF190_8_97885717_97888667_97911504_97913312_FF OBD159_3117 TGTTGTTGGACCTATCTGAGCAAAGG
232 ORF191_19_46459835_46460902_46479838_46481514_RF OBD159_3121 CAGTCTTGGCTGGTGATGATTCCTGA
233 ORF191_9_28333777_28339631_28374860_28379516_FF OBD159_3125 GCCTAAGTCCAGTAGTATGGTGGCTG
234 ORF194_4_15556941_15559956_15665131_15667839_RR OBD159_3129 GGAGAGATTTGTGCCAGACTACAGTG
235 ORF195_8_97885717_97888667_97955459_97960176_FR OBD159_3133 TGTTGTTGGACCTATCTGAGCAAAGG
236 ORF197_9_33260644_33262136_33317596_33319558_RR OBD159_3137 GTTCCAGTTCAGGAGCCTCTCTC
237 ORF197_X_101076588_101078760_101106636_101109429_FF OBD159_3141 CATAACCTCCCTTCTCCCCATTT
238 ORF198_13_45792577_45800189_45859224_45860475_RR OBD159_3145 GCAGCATTCCTGTATGTGGTTTGACT
239 ORF198_14_73418771_73426644_73454993_73457655_RR OBD159_3149 AAGGAAGAAGAGTCACCATAGGAC
240 ORF198_2_164430286_164435469_164495161_164496648_FF OBD159_3153 GGTGTGTGTTTATGTGTGACTATTTG
表4.b7
   PCR- 引子 2_ID PCR_ 引子 2 標記 GLMNET
121 OBD159_2703 GAACTGGAGGAGGGTGGATAGGG OBD159_2701_2703 -0.005199586
122 OBD159_2707 GGTTCTAAAGTTCCATTTGGTTCTCC OBD159_2705_2707 -0.00386514
123 OBD159_2711 GACACCTGGCAGCAGTCATTTACAGT OBD159_2709_2711 -0.000800747
124 OBD159_2715 TTCTTCAATGGCTCCTGATGCTTAGC OBD159_2713_2715 -0.003111828
125 OBD159_2719 TCCTTTCCTGAGAGAGTAGGGATA OBD159_2717_2719 0
126 OBD159_2723 CTTTTACTTCAGGGACCCCAGGTGTC OBD159_2721_2723 -0.000781517
127 OBD159_2727 TTATTCTACCCTTCCTGCCCTGCCCT OBD159_2725_2727 -0.005003739
128 OBD159_2731 GTTCGGCTTGATGGCAGAGACTC OBD159_2729_2731 -0.004794101
129 OBD159_2735 AGACTGTGATTCCCAGGGCAGGA OBD159_2733_2735 -0.00222434
130 OBD159_2739 CTCAAAGCCATCTCCTGGTAGGG OBD159_2737_2739 -0.003039333
131 OBD159_2743 CTGGGACTACTTAGGTATGAGCCACC OBD159_2741_2743 -0.002011716
132 OBD159_2747 GGGAAAGAGCAACAGGAGACACC OBD159_2745_2747 -0.001455236
133 OBD159_2751 CATAAACTCCTACCAACTAAGAAT OBD159_2749_2751 -0.001882457
134 OBD159_2755 TTTCTACAGATACGCACCCACACAGA OBD159_2753_2755 -0.001287372
135 OBD159_2759 TCAGGCTTGGGCTCTGTAATGGAG OBD159_2757_2759 -0.001564398
136 OBD159_2763 TACTGGAAAGGATGTCTTCTGGG OBD159_2761_2763 -0.002351873
137 OBD159_2767 GACTGTTTTCAGAGACAATGGAAT OBD159_2765_2767 -0.001384665
138 OBD159_2771 TCCCTGTAATCCCAGCATTTTGG OBD159_2769_2771 -0.000490727
139 OBD159_2775 CTCCACTTCTACCACCACGAGTA OBD159_2773_2775 -0.001637816
140 OBD159_2779 AAGAGACAGACAGGCTGGGCGTG OBD159_2777_2779 -0.001512532
141 OBD159_2783 GCATTCGGTTATCTGTTTGCTTACTT OBD159_2781_2783 -0.001942432
142 OBD159_2787 TGGAAACTGGGAGAGGAGACAGC OBD159_2785_2787 -0.000541437
143 OBD159_2791 TCATCGTCAGACCCAAGATACTTTTG OBD159_2789_2791 -0.000989294
144 OBD159_2795 GTGGGAAAGGATGGAGAGTTGGATGA OBD159_2793_2795 -0.000474951
145 OBD159_2799 CAGGTTGTGTGTGGGAGTAGAAAGTC OBD159_2797_2799 -0.000312322
146 OBD159_2803 TACTAAGAGGTAGAGTGAGACAGC OBD159_2801_2803 -0.001333616
147 OBD159_2807 CCTTTATCTTCCCTACCCCATCAT OBD159_2805_2807 -0.00268597
148 OBD159_2811 CCTGTCTCAGCCTCCCAAGTAGC OBD159_2809_2811 -0.002796481
149 OBD159_2815 CGGCTTCAGGCATACACACACAC OBD159_2813_2815 -0.003896386
150 OBD159_2819 CCTTCTGGGACACTGCCCCTGTG OBD159_2817_2819 -0.002180365
151 OBD159_2823 AGAGGCACCAGATGCGGAGGAAG OBD159_2821_2823 -0.000683876
152 OBD159_2827 GTGTATGTAACTGAACAAAGTGAGTC OBD159_2825_2827 -0.005220708
153 OBD159_2831 GACTACATTTCTCATTTTACTGAA OBD159_2829_2831 -0.002177987
154 OBD159_2835 GGACTACAGGCGTGAGCCACCAC OBD159_2833_2835 -0.003736644
155 OBD159_2839 GACAGAGACTTGTAGATTGGTTCAAA OBD159_2837_2839 -0.001662501
156 OBD159_2843 GACCCATTCTATCCCCTCTACTCTGC OBD159_2841_2843 0.00026099
157 OBD159_2847 AATGTAAATGTTCTAATGGACACA OBD159_2845_2847 -0.000527032
158 OBD159_2851 GGATGAGCCTGTGGTCCCTTAGG OBD159_2849_2851 -0.003482728
159 OBD159_2855 TAATGACCTCCAGCCCCATCCAT OBD159_2853_2855 -0.001948276
160 OBD159_2859 GCGAGTGTGATGAGGTTTGCTTTATG OBD159_2857_2859 -0.002278956
161 OBD159_2863 CCACTTGCTACCTGTGTGATACTGAC OBD159_2861_2863 -0.001062091
162 OBD159_2867 CTTTCACTAATGTGTGGTCTGTGGCA OBD159_2865_2867 -0.004588914
163 OBD159_2871 TTCCCTGCCTTCCTACTCTTCTTGGG OBD159_2869_2871 -0.000586293
164 OBD159_2875 GGAGCCCTTGGTCTTGTAATCTGAGC OBD159_2873_2875 -0.004296281
165 OBD159_2879 CTGGAGTGAGAAGGAAGGGCAGTTTC OBD159_2877_2879 -0.000700999
166 OBD159_2883 GGAATCCCCTCCTGTGTGCCAGC OBD159_2881_2883 -0.003629345
167 OBD159_2887 CGAGTAGGATGAGAAGGGCACCC OBD159_2885_2887 -0.002670683
168 OBD159_2891 GTGCTGTTTGCCAACTGGTATGGGAC OBD159_2889_2891 -0.006025308
169 OBD159_2895 ATCAGTGTTTTCTCCTCTCAAATA OBD159_2893_2895 -0.002350922
170 OBD159_2899 TTTCCCTACTTTCTTGCTGTGTGACC OBD159_2897_2899 -0.002421424
171 OBD159_2903 GGACATAAGCCCAAACAGGAACACTG OBD159_2901_2903 -0.003189291
172 OBD159_2907 TTTGAGGTGAGTCTGGCTAAACACAG OBD159_2905_2907 -0.000912764
173 OBD159_2911 CTATTTGGATTGTTGAAAGCCTTGGT OBD159_2909_2911 -0.001621343
174 OBD159_2915 GCCTTGCCAGAAAGCACACAGAG OBD159_2913_2915 -0.000839095
175 OBD159_2643 TACGGAAGATGGAAGTGAGGTGC OBD159_2641_2643 -0.004245992
176 OBD159_2919 GACAAGAGTCCTATCTGGGCTCC OBD159_2917_2919 -0.003670895
177 OBD159_2923 AGAGCAGCAAATCCGTGACTGGG OBD159_2921_2923 -0.002626094
178 OBD159_2924 AGAGCAGCAAATCCGTGACTGGG OBD159_2922_2924 -0.004391165
179 OBD159_2925 AGAGCAGCAAATCCGTGACTGGG OBD159_2923_2925 -0.002337738
180 OBD159_2827 GTGTATGTAACTGAACAAAGTGAGTC OBD159_2825_2827 -0.004038653
181 OBD159_2935 CCTGTGCTCTGCTGTAGTGGAGA OBD159_2933_2935 -0.002474537
182 OBD159_2939 GAAATGAGTAGTTGTGACAGAGGTTG OBD159_2937_2939 -0.002696675
183 OBD159_2943 CTAATCAATCTCACGCTGCTACATAA OBD159_2941_2943 -0.004107571
184 OBD159_2947 ATGCCTTTTCTGATGTTCTGCTGATA OBD159_2945_2947 -0.005210227
185 OBD159_2951 AGAAGTGAAAGAGCAATGAAAATG OBD159_2949_2951 -0.002750521
186 OBD159_2955 CGTGCGACAAGGACTGGGACAAA OBD159_2953_2955 -0.004135271
187 OBD159_2959 TAGGGCTTGAGGCTTTGGGTGGAATA OBD159_2957_2959 0
188 OBD159_2963 CCCACCCTTGTTTGATTTCCCCTCAT OBD159_2961_2963 -0.003123212
189 OBD159_2967 GTAGACTGAGTAACTTGTAAAGCCTC OBD159_2965_2967 -0.002403132
190 OBD159_2971 GGACTACAGGCGTGAGCCACCAC OBD159_2969_2971 -0.003087019
191 OBD159_2975 ATCATCAGAGGATTACTCAGAGGG OBD159_2973_2975 -0.001260663
192 OBD159_2979 GTCTCTTCACTGTCCAGGTAACCCTC OBD159_2977_2979 -0.00070886
193 OBD159_2983 GCTGAAGACTTGGTCAAACCTATGGC OBD159_2981_2983 -0.003981238
194 OBD159_2987 CCTCCCCAGTCAGGATGGTTAGA OBD159_2985_2987 -0.000151475
195 OBD159_2991 AAGGCACCCAGGTTGGAAAAGAAAA OBD159_2989_2991 -0.003726158
196 OBD159_2995 GCTGCCCCAGAGGTCTTCACATC OBD159_2993_2995 -0.003699263
197 OBD159_2999 GGCGTGATTTACATTCCCAGCCG OBD159_2997_2999 -0.00081063
198 OBD159_3003 CCACCATCCCTCACCCTACACATCTT OBD159_3001_3003 -0.001691504
199 OBD159_3007 GCATCTGAAAGAGGAGGAGGAGG OBD159_3005_3007 -0.004612101
200 OBD159_3011 GGAAACTGAAACCGTAACAAGGAACA OBD159_3009_3011 -0.003361251
201 OBD159_3015 GTCTGGCACAAGAAAGGGCTCAATGA OBD159_3013_3015 -0.001803071
202 OBD159_3019 TGAGTTGCTGGGACCACAGGCAT OBD159_3017_3019 -0.001642618
203 OBD159_2259 AAGGATTGCTTGAGCCCAGGAAT OBD159_2257_2259 -0.003723422
204 OBD159_3023 GACACCTCCAGGCTACACAGACA OBD159_3021_3023 -0.003729313
205 OBD159_2763 TACTGGAAAGGATGTCTTCTGGG OBD159_2761_2763 -0.001159911
206 OBD159_3027 GGTGGGCTGAGTAAACGGGACAG OBD159_3025_3027 -0.001211322
207 OBD159_3031 CAACCCTGCCACGGAAAACAAAACAA OBD159_3029_3031 -0.001896747
208 OBD159_3035 CTCACTAATGACATCCCACATCGCAG OBD159_3033_3035 -0.003274088
209 OBD159_3039 CACCTGTAATCCCAGCACTTTGG OBD159_3037_3039 -0.002950916
210 OBD159_3043 GGCAACAGAATGAGACCCTATCT OBD159_3041_3043 -0.001179682
211 OBD159_3047 GGCTCACACCTGTAATCCCAGCG OBD159_3045_3047 -0.001995391
212 OBD159_3051 TCCACATCCCACCTTGACCTCTTCCT OBD159_3049_3051 -0.003219045
213 OBD159_3055 GTCCCACCTCCCAATACTATGGC OBD159_3053_3055 -0.000934073
214 OBD159_3059 CCTCTCAGCCTTCATCTTTGTATTTG OBD159_3057_3059 -0.000323198
215 OBD159_3063 GCCCAATGACAGAGCATCAAAACACA OBD159_3061_3063 -0.004041529
216 OBD159_3067 GAGAGAAACTAAAGTCCAGGAGAC OBD159_3065_3067 -0.001510221
217 OBD159_3071 CAGCACTTTCCACTTCTAAAATCAGA OBD159_3069_3071 -0.001925997
218 OBD159_3075 CGGAGTCTTGCTCTGTTGCGAGG OBD159_3073_3075 -0.003238351
219 OBD159_2283 CCCAAACTCCAAAGGCAGCGTGC OBD159_2281_2283 -0.004372167
220 OBD159_3079 GAGAGAAGTGAGGAAAAGTGGCTA OBD159_3077_3079 -0.004477186
221 OBD159_3083 GACATCCTGCTCCCCATAGTGGA OBD159_3081_3083 -0.002043805
222 OBD159_3087 GGCTGGGAGAGGTTAGAGATGAC OBD159_3085_3087 -0.002297286
223 OBD159_3091 CCAGTTATCGTTTTGTAGGTAGACCA OBD159_3089_3091 -0.000431389
224 OBD159_3095 TGGATTGTTCTTTAGATTTCAGATA OBD159_3093_3095 -0.002186565
225 OBD159_2255 GTCACTTGTGCTAAATGCCACTTC OBD159_2253_2255 -0.002406363
226 OBD159_3099 GAAGCAGAAGAAGGAGCAAGAAAG OBD159_3097_3099 -0.004446875
227 OBD159_3103 CTCCACTTCTACCACCACGAGTA OBD159_3101_3103 -0.001580657
228 OBD159_3107 GCTATGGCAACAACCTGTGGAGG OBD159_3105_3107 -0.002607721
229 OBD159_3111 CCATCATCGGTTGAATCCACAGAT OBD159_3109_3111 0.000618635
230 OBD159_3115 GAGGACACATTGGGCAGGAAACATCC OBD159_3113_3115 -0.002793281
231 OBD159_3119 CCATCCACCCCACTTCATCCTTTGTG OBD159_3117_3119 -0.000906288
232 OBD159_3123 CCCTTCAGTGGAACCTTACCCAACAA OBD159_3121_3123 -0.004160869
233 OBD159_3127 GTGGTGTGGTTCAAAGAGCACTGTAA OBD159_3125_3127 -0.00360644
234 OBD159_3131 AACAACCCGCCACTGGAACCCTTTTA OBD159_3129_3131 -0.00408779
235 OBD159_3135 GTCTTGGTGTTCCTTACGGTGCCTGT OBD159_3133_3135 -0.000833178
236 OBD159_3139 GGACTACAGGCGTGAGCCACCAC OBD159_3137_3139 -0.002757562
237 OBD159_3143 CGCCCAGCCTAATGTGAGATTTT OBD159_3141_3143 -0.000664345
238 OBD159_3147 CTGCCCTCTTCCTTTCCCTCCTGTAT OBD159_3145_3147 -0.004969047
239 OBD159_3151 TTTTATTTTCATTTGGAAGACTGC OBD159_3149_3151 -0.000603516
240 OBD159_3155 AAGGACAATAGGGATGTAAACACACA OBD159_3153_3155 -0.001805771
表4.b8
   基因
121 CCDC85A; rs6747380
122 BEX4; NXF3
123 GALNT2; rs4925506
124 rs62259232; rs35360328
125 ANKRD55; rs715180
126 PIWIL2; SLC39A14; rs879253763
127 PPM1K; rs6819344; rs7661312; rs2869926; rs881561; rs893971; rs17732955; rs9637599; rs4423843; rs4693210; rs958325; rs13128713; rs6845249; rs34813495; rs7655241; rs28406500; rs10024717; rs4693946; rs7678928; rs13151250; rs28375859; rs11931633; rs9995984; rs10018448; rs1440581; rs1440580; rs17013995; rs17789621; rs7676986; rs7677533; rs7660693; rs6841731; rs1899132; rs28789746; rs9998450; rs4693947; rs28884607; rs6532063; rs1595911; rs1595910; rs1808860; rs1808859; rs28504259; rs1545207; rs10022462; rs17014018; rs4693211; rs4693950; rs12512051
128 KCNC4; SLC6A17; UBL4B; rs775085213; rs375380880
129 PLA2G4A; rs4140564
130 HHAT; rs116161686; rs34585985
131 EMP1; rs1479119
132 EMP1; rs1479119
133 E2F6; GREB1; rs77294520
134 rs10929925; rs16864170
135 GAFA3; PGM2; PTTG2; TBC1D1; rs17578878; rs35859249
136 SGK1; rs1743966; rs1009840; rs4896030; rs9493873
137 TBX18; rs869320679; rs797045022; rs77693245
138 DEPTOR; DSCC1; TAF2
139 PLS3; rs201386833
140 ANKRD6; LYRM2; rs78571182
141 rs111611512
142 ATL2; CYP1B1
143 CDH9; rs201058683
144 LIFR; rs185111230
145 CDH9; rs201058683
146 KIF13B; rs75609241
147 METTL25; TMTC2
148 AC109829.1; FNDC4; GCKR; rs8395; rs2303369; rs704795; rs780090; rs146175795; rs813592; rs1260320; rs149847328; rs2293572; rs2293571; rs1260326; rs3817588; rs4425043; rs6547692; rs780096; rs780095; rs780094; rs780093; rs780092; rs814295; rs11681351; rs704790; rs8179252; rs1260334; rs1260333; rs1313566; rs2950835; rs200826320; rs2911711; rs6753534; rs4665985; rs4665987; rs12473139; rs4665991
149 SNX29; rs12922317
150 rs111611512
151 GALNT2; rs4925506
152 SNX29; rs12922317
153 CD109; SLC17A5
154 CHMP5; NFX1
155 TCEAL7; WBP5
156 KIF20B; rs181778161
157 SGK1; rs9493873
158 rs7015657; rs500816
159 C9orf3; rs7026071
160 IL13RA1; rs3121672; rs2250747
161 CCDC160; PHF6
162 RBM20; rs267607001; rs183007628
163 RAPGEF5; STEAP1B
164 MDGA1; rs9462343
165 MATN2; rs6987225
166 C11orf70; KIAA1377
167 LACRT; PPP1R1A
168 AMIGO2; SLC38A4
169 DPP8; PTPLAD1; VWA9; rs352479; rs9635366; rs352476; rs2456015; rs2456009; rs12916360; rs11632310; rs12906196; rs7165102
170 AMELX; ARHGAP6
171 ADCY2; rs12522444; rs11134242; rs4530734; rs12519539
172 CLIC5; RUNX2
173 GPR125; KCNIP4
174 MATN2; rs6987225
175 SLC6A17; rs375380880; rs775085213
176 KCNC4; SLC6A17; UBL4B; rs775085213; rs375380880
177 LMO3; MGST1; rs10505799
178 OLFM4; rs12552; rs9568797
179 CYFIP1; NIPA1; NIPA2; rs4778334; rs371775791; rs576755299
180 SNX29; rs12922317
181 DHRS9; LRP2; rs80338753; rs202057289; rs80338754; rs764880181; rs4667594; rs786205122; rs2075252
182 C9orf3; rs10993397; rs10761362; rs4385527
183 CRLF2; CSF2RA
184 rs5916200
185 rs12487066
186 TMEM242; ZDHHC14
187 CSMD3; rs189590409
188 RASSF8; rs1546550
189 rs1660895; rs13013037
190 BAG1; CHMP5; NFX1; SPINK4; rs706118; rs3758271
191 ELK3; rs4762284
192 MATN2; rs6987225
193 MAP2; rs9288410; rs146432517
194 AL356135.1; KHDRBS2; rs140996952; rs76014404
195 rs2337901; rs11897825
196 ROBO1; rs919603543
197 LAPTM4B; MATN2; rs6987225
198 DNAH7; SLC39A10
199 KCNC4; SLC6A17; UBL4B; rs775085213; rs375380880
200 rs11116045; rs1545843
201 E2F6; GREB1; rs77294520
202 PUM2; rs111612372
203 CXADR
204 RNF175; TLR2; rs1898830; rs748086774; rs3804099; rs3804100; rs5743704; rs121917864; rs5743708; rs7656411
205 SGK1; rs1743966; rs1009840; rs4896030; rs9493873
206 PARK2; rs566229879; rs765648938; rs137853057; rs778798543; rs747984930
207 FAM47C; PRRG1
208 CCDC85A; rs186920977; rs6747380; rs17268785
209 PI4KA; SERPIND1; rs777006911; rs587777759; rs5907; rs142451096; rs121912420; rs587777760
210 ERI1; PPP1R3B; rs189798; rs9949; rs3748140; rs7011581; rs6998837; rs6999855; rs378974; rs440932; rs365309; rs3748136
211 RD3; rs11579557
212 KIF20B; rs181778161
213 UVRAG; rs7933235
214 TENM2; rs9647570
215 CCDC144A; RP11-219A15.1
216 CD109; SLC17A5
217 C6orf211; CCDC170; RMND1; rs370863743; rs6933660; rs1971256; rs9479055; rs6931664
218 AGBL4; SPATA6; rs2803270
219 SLC6A17; rs775085213
220 CAPN2; TP53BP2
221 EMP1; rs1479119
222 CYFIP1; NIPA2; rs4778334; rs371775791; rs576755299
223 PTPN2; rs514000; rs11875687; rs657555
224 REG3G
225 CXADR
226 NR2F1; rs587777277
227 PLS3; rs201386833
228 AGBL4; SPATA6; rs2803270
229 CCL3L3; CCL4L1; TBC1D3B; TBC1D3I
230 GPM6A; rs13144140
231 LAPTM4B; MATN2
232 PNMAL1; PNMAL2; PPP5D1
233 LINGO2; rs7851437
234 CC2D2A; FBXL5; rs200904521; rs863225178; rs764719093; rs386833748; rs118204053; rs773881370; rs370880399; rs386833749; rs863225173; rs386833750; rs863225169; rs386833751; rs386833752; rs267606709; rs118204051; rs386833753; rs863225170; rs386833754; rs386833755; rs386833756; rs760918829; rs375278294; rs863225171; rs863225172; rs386833757; rs779823379; rs754586025; rs763735590; rs386833758; rs386833759; rs576298659; rs758036385; rs763486732; rs794729225; rs386833760; rs886044295; rs863225176; rs863225168; rs7684446; rs387907058; rs368720062; rs587779732; rs797045437; rs863225179; rs386833762; rs780673487; rs118204052; rs763425007; rs201502401; rs863225174; rs863225175; rs1134634
235 MATN2; rs6987225
236 BAG1; CHMP5; NFX1; rs706118; rs3758271
237 CENPI; TMEM35; TRMT2B
238 SIAH3; rs75061684
239 HEATR4; NUMB
240 GRB14; rs8192673
表4.b9
   基因集 基因集中之數目 在清單中 P值
1 鈣黏蛋白信號傳導路徑(P) 100 7 0.000749
2 甲狀腺激素合成(K) 74 6 0.000848
3 麩胺酸能突觸(K) 114 7 0.00158
4 Wnt信號傳導路徑(P) 267 11 0.00209
5 5HT1型受體介導之信號傳導路徑(P) 19 3 0.00288
6 5ΗT4型受體介導之信號傳導路徑(P) 23 3 0.00490
7 葡糖胺聚糖生物合成-硫酸乙醯肝素/肝素(K) 24 3 0.00551
8 軸突蛋白及神經配蛋白(R) 50 4 0.00658
9 ECM-受體相互作用(K) 82 5 0.00753
10 β1腎上腺素激導性受體信號傳導路徑(P) 27 3 0.00760
11 mTOR信號傳導路徑(K) 154 7 0.00803
12 GABA能突觸(K) 88 5 0.01
13 嗎啡鹼成癮(K) 91 5 0.0114
14 G α (12/13)信號傳導事件(R) 60 4 0.0122
15 CXCR3介導之信號傳導事件(N) 35 3 0.0152
16 Apelin信號傳導路徑(K) 136 6 0.0157
17 長時程增強(K) 67 4 0.0176
18 鐸樣受體級聯(R) 143 6 0.0195
19 異三聚體G蛋白信號傳導路徑-Gi α及Gs α介導之路徑(P) 147 6 0.022
20 LPA4介導之信號傳導事件(N) 16 2 0.0235
21 氧化氮信號傳導路徑(B) 17 2 0.0262
22 整合素相關激酶信號傳導(N) 45 3 0.0291
23 弓蟲病(K) 118 5 0.0308
24 網格蛋白介導之內吞作用(R) 118 5 0.0308
25 CXCR4介導之信號傳導事件(N) 80 4 0.0309
26 G α (i)信號傳導事件(R) 345 10 0.0317
27 Notch介導之HES/HEY網絡(N) 47 3 0.0325
28 抗微生物肽(R) 47 3 0.0325
29 瘧疾(K) 49 3 0.0361
30 β2腎上腺素激導性受體信號傳導路徑(P) 21 2 0.0386
31 β3腎上腺素激導性受體信號傳導路徑(P) 21 2 0.0386
32 孕酮如何引發卵母細胞成熟(B) 21 2 0.0386
33 催產素受體介導之信號傳導路徑(P) 21 2 0.0386
34 小細胞肺癌(K) 86 4 0.0386
35 肌肉萎縮性側索硬化症(ALS)(K) 51 3 0.0398
36 GABA-B_受體_II_信號傳導(P) 3 1 0.043
37 Hedgehog『關閉』狀態 90 4 0.0444
38 G α (z)信號傳導事件(R) 23 2 0.0454
39 麩胱甘肽代謝(K) 54 3 0.0458
40 能量代謝整合(R) 92 4 0.0474
41 內皮素信號傳導路徑(P) 55 3 0.0479
42 經由HIF活化的低氧應答(P) 24 2 0.049
43 轉錄因子creb及其胞外信號(B) 24 2 0.049
44 藉由VEGF進行信號傳導(R) 94 4 0.0505
45 其他介白素信號傳導(R) 25 2 0.0526
46 C-MYC路徑(N) 25 2 0.0526
47 促腎上腺皮質激素釋出因子受體信號傳導路徑(P) 25 2 0.0526
48 晝夜節律(K) 96 4 0.0538
49 5HT2型受體介導之信號傳導路徑(P) 26 2 0.0564
50 抗利尿素經由水孔蛋白調節腎水內穩定(R) 26 2 0.0564
51 蛋白聚糖多配體蛋白聚糖介導之信號傳導事件(N) 4 1 0.057
52 蕈毒鹼乙醯膽鹼受體2及4信號傳導路徑(P) 4 1 0.057
53 半乳糖分解代解(R) 4 1 0.057
54 內分泌抗性(K) 98 4 0.0571
55 阿米巴病(Amoebiasis) (K) 98 4 0.0571
56 趨化細胞素信號傳導路徑(K) 187 6 0.0585
57 三酸甘油酯代謝(R) 27 2 0.0602
58 Wnt信號傳導路徑(K) 143 5 0.0606
59 雌激素信號傳導路徑(K) 100 4 0.0606
60 大自體吞噬(R) 61 3 0.0614
61 逆行內源性類大麻酚信號傳導(K) 101 4 0.0624
62 二十碳四烯酸代謝(K) 62 3 0.0638
63 IL8及CXCR1介導之信號傳導事件(N) 28 2 0.0642
64 ErbB4信號傳導事件(N) 28 2 0.0642
65 癌症中之路徑(K) 397 10 0.0685
66 壽命調節路徑-多物種(K) 64 3 0.0688
67 心肌細胞中之腎上腺素信號傳導(K) 149 5 0.0695
68 PI代謝(R) 65 3 0.0713
69 鐸樣受體信號傳導路徑(K) 106 4 0.0717
70 磷酸戊糖路徑(K) 30 2 0.0723
71 β1整合素細胞表面相互作用(N) 66 3 0.0739
72 吞噬體(K) 154 5 0.0775
73 DAG及IP3信號傳導(R) 32 2 0.0808
74 G蛋白β：γ信號傳導(R) 32 2 0.0808
75 阿茲海默症-早老素路徑(P) 111 4 0.0816
76 參與巨核細胞發育及血小板生產之因子(R) 111 4 0.0816
77 癌症中之蛋白聚糖(K) 205 6 0.0826
78 β-連環蛋白非依賴性WNT信號傳導(R) 112 4 0.0837
79 HTLV-I感染(K) 258 7 0.0868
80 嗜中性白血球脫粒(R) 418 10 0.089
81 IL8及CXCR2介導之信號傳導事件(N) 34 2 0.0895
82 ErbB1之內化(N) 35 2 0.094
83 Arf6信號傳導事件(N) 35 2 0.094
84 由Akt介導之I類PI3K信號傳導事件(N) 35 2 0.094
85 蛋白質泛素化(R) 74 3 0.0959
86 ATR信號傳導路徑(N) 37 2 0.1031
87 亨丁頓病(Huntington disease) (P) 122 4 0.1058
88 類視黃素代謝及轉運(R) 38 2 0.1077
89 RAC1活性之調節(N) 38 2 0.1077
90 上皮細胞之細菌侵入(K) 78 3 0.1079
91 AMPK信號傳導路徑(K) 124 4 0.1105
92 卵母細胞減數分裂(K) 124 4 0.1105
93 快速糖皮質激素信號傳導(N) 8 1 0.1107
94 帕金蛋白在泛蛋白-蛋白酶體路徑中之作用(B) 8 1 0.1107
95 由肝細胞生長因子受體(c-Mct)介導之信號傳導事件(N) 80 3 0.114
96 FOXM1轉錄因子網絡(N) 40 2 0.1172
97 尼古丁成癮(K) 40 2 0.1172
98 軸突導引(K) 177 5 0.1203
99 醛固酮合成及分泌(K) 82 3 0.1203
100 有絲分裂細胞週期之調節(R) 83 3 0.1235
表5.a1
   FDR 節點 基因集中蛋白質之比率
1 0.2306 FZD3,FZD9,CTNNA2,PCDHGA3,PCDHGA2,PCDHGA1,PCDH8 0.0089
2 0.2306 ADCY2,SLC26A4,GPX6,GPX5,GPX7,LRP2 0.0066
3 0.284 PPP3R1,GRIN2B,DLGAP1,ADCY2,GRK3,GRM1,GNG2 0.0102
4 0.284 SFRP2,FZD3,FZD9,CTNNA2,MYCN,PPP6C,PCDHGA3,PCDHGA2,PCDHGA1,GNG2,PCDH8 0.0239
5 0.3144 ADCY2,SNAP25,GNG2 0.0017
6 0.337 ADCY2,SNAP25,GNG2 0.0021
7 0.337 NDST4,GLCE,EXTL3 0.0021
8 0.337 GRIN2B,DLGAP1,GRM1,NLGN4X 0.0045
9 0.337 SDC1,LAMA4,LAMA3,THBS2,SV2B 0.0073
10 0.337 ADCY2,SNAP25,GNG2 0.0024
11 0.337 SKP2,ATP6V1G1,FZD3,FZD9,RICTOR,PIK3CG,MTOR 0.0138
12 0.337 GABARAPL1,GABRG2,ADCY2,GNG2,PLCL1 0.0079
13 0.337 GABRG2,ADCY2,GRK3,OPRM1,GNG2 0.0081
14 0.337 TIAM2,RHOB,ARHGEF7,GNG2 0.0054
15 0.337 RICTOR,GNG2,MTOR 0.0031
16 0.337 GABARAPL1,MYL3,ADCY2,PIK3CG,GNG2,MTOR 0.0122
17 0.337 PPP3R1,GRIN2B,PPP1R1A,GRM1 0.006
18 0.337 RPS6KA5,CTSB,TLR2,TAB2,LBP,BPI 0.0128
19 0.337 PRKAR2B,ADCY2,GRK3,GRM1,OPRM1,GNG2 0.0131
20 0.337 RPS6KA5,ADCY2 0.0014
21 0.337 PRKAR2B,GRIN2B 0.0015
22 0.337 ARHGEF7,RICTOR,ELMO2 0.004
23 0.337 TLR2,TAB2,PIK3CG,LAMA4,LAMA3 0.0105
24 0.337 SNX9,AMPH,GRK3,SYNJ2,LRP2 0.0105
25 0.337 RHOB,RICTOR,GNG2,MTOR 0.0072
26 0.337 PPP3R1,PRKAR2B,SDC1,ADCY2,CXCR6,OPRM1,SLC24A1,LRP2,GNG2,METAP2 0.0308
27 0.337 RUNX2,GATA4,GHR 0.0042
28 0.337 TLR2,DCD,BPI 0.0042
29 0.337 SDC1,TLR2,THBS2 0.0044
30 0.337 SNAP25,GNG2 0.0019
31 0.337 SNAP25,GNG2 0.0019
32 0.337 PAQR5,PRKAR2B 0.0019
33 0.337 SNAP25,GNG2 0.0019
34 0.337 SKP2,PIK3CG,LAMA4,LAMA3 0.0077
35 0.337 PPP3R1,GRIN2B,DERL1 0.0046
36 0.337 ADCY2 0.0003
37 0.337 IFT172,PSMD6,PRKAR2B,NUMB 0.008
38 0.337 ADCY2,GNG2 0.0021
39 0.337 GPX6,GPX5,GPX7 0.0048
40 0.337 PRKAR2B,ADCY2,SNAP25,GNG2 0.0082
41 0.337 PRKAR2B,ADCY2,PIK3CG 0.0049
42 0.337 PIK3CG,MTOR 0.0021
43 0.337 RPS6KA5,PRKAR2B 0.0021
44 0.337 CYFIP1,RICTOR,ELMO2,MTOR 0.0084
45 0.337 SDC1,SNAP25 0.0022
46 0.337 SKP2,FBXW7 0.0022
47 0.337 SNAP25,GNG2 0.0022
48 0.337 RPS6KA5,GRIN2B,ADCY2,GNG2 0.0086
49 0.337 SNAP25,GNG2 0.0023
50 0.337 PRKAR2B,ADCY2 0.0023
51 0.337 SDC1 0.0004
52 0.337 PRKAR2B 0.0004
53 0.337 PGM2 0.0004
54 0.337 ADCY2,ABCB11,PIK3CG,MTOR 0.0088
55 0.337 TLR2,PIK3CG,LAMA4,LAMA3 0.0088
56 0.337 XCR1,ADCY2,CXCR6,GRK3,PIK3CG,GNG2 0.0167
57 0.337 DGAT2,GPD2 0.0024
58 0.337 SFRP2,PPP3R1,FZD3,FZD9,PRICKLE2 0.0128
59 0.337 ADCY2,PIK3CG,GRM1,OPRM1 0.0089
60 0.337 GABARAPL1,UVRAG,MTOR 0.0055
61 0.337 GABRG2,ADCY2,GRM1,GNG2 0.009
62 0.337 GPX6,GPX5,GPX7 0.0055
63 0.337 PIK3CG,GNG2 0.0025
64 0.337 GRIN2B,TAB2 0.0025
65 0.337 SKP2,FZD3,FZD9,ADCY2,CTNNA2,PIK3CG,LAMA4,LAMA3,GNG2,MTOR 0.0355
66 0.337 ADCY2,PIK3CG,MTOR 0.0057
67 0.337 RPS6KA5,MYL3,PPP1R1A,ADCY2,PIK3CG 0.0133
68 0.337 SBF2,SYNJ2,PIK3CG 0.0058
69 0.337 TLR2,TAB2,PIK3CG,LBP 0.0095
70 0.337 PGM2,FBP1 0.0027
71 0.337 LAMA4,LAMA3,THBS2 0.0059
72 0.337 ATP6V1G1,OLR1,TLR2,TUBB8,THBS2 0.0138
73 0.337 PRKAR2B,ADCY2 0.0029
74 0.337 PIK3CG,GNG2 0.0029
75 0.337 FZD3,FZD9,CTNNA2,LRP2 0.0099
76 0.337 GATA4,PRKAR2B,KIF23,PHF21A 0.0099
77 0.337 FZD3,FZD9,SDC1,TLR2,PIK3CG,MTOR 0.0183
78 0.337 PSMD6,PPP3R1,FZD3,GNG2 0.01
79 0.337 PPP3R1,FZD3,FZD9,ADCY2,PTTG1,PTTG2,PIK3CG 0.0231
80 0.337 CYFIP1,PSMD6,OLR1,CTSB,TLR2,CD59,SNAP25,PGM2,CHI3L1,BPI 0.0374
81 0.337 PIK3CG,GNG2 0.003
82 0.337 ARHGEF7,AMPH 0.0031
83 0.337 KIF13B,IPCEF1 0.0031
84 0.337 RICTOR,MTOR 0.0031
85 0.337 SHPRH,DERL1,UBE2G1 0.0066
86 0.337 NBN,RFC3 0.0033
87 0.337 CYFIP1,GRIN2B,TUBB8,DNAH7 0.0109
88 0.337 SDC1,LRP2 0.0034
89 0.337 TIAM2,ARHGEF7 0.0034
90 0.337 CTNNA2,ELMO2,PIK3CG 0.007
91 0.337 PIK3CG,TBC1D1,FBP1,MTOR 0.0111
92 0.337 PPP3R1,ADCY2,PTTG1,PTTG2 0.0111
93 0.337 GNG2 0.0007
94 0.337 UBE2G1 0.0007
95 0.337 RIN2,NUMB,MTOR 0.0072
96 0.337 SKP2,LAMA4 0.0036
97 0.337 GABRG2,GRIN2B 0.0036
98 0.337 PPP3R1,FZD3,EFNB1,PLXNA2,PIK3CG 0.0158
99 0.337 ADCY2,NR4A2,CAMK1D 0.0073
100 0.337 PSMD6,SKP2,PTTG1 0.0074
表5.a2
   基因集 基因集中之數目 在清單中 P值
101 EGFR依賴性內皮素信號傳導事件(N) 9 1 0.1237
102 肉毒桿菌毒素之作用(N) 9 1 0.1237
103 磷酸戊糖路徑(單磷酸己糖分流) (R) 9 1 0.1237
104 代謝型麩胺酸受體第II族路徑(P) 9 1 0.1237
105 經由MMEJ之HDR(alt-NHEJ) (R) 9 1 0.1237
106 卡波西氏肉瘤(Kaposi's sarcoma)相關疱疹病毒感染(K) 180 5 0.1265
107 PI3K-Akt信號傳導路徑(K) 341 8 0.13
108 PAR1介導之凝血酶信號傳導事件(N) 43 2 0.1318
109 LKB1信號傳導事件(N) 43 2 0.1318
110 β3整合素細胞表面相互作用(N) 43 2 0.1318
111 EPH-Ephrin信號傳導(R) 86 3 0.1333
112 FoxO信號傳導路徑(K) 134 4 0.1354
113 Hedgehog信號傳導路徑(P) 10 1 0.1364
114 維生素D代謝及路徑(P) 10 1 0.1364
115 5HT3型受體介導之信號傳導路徑(P) 10 1 0.1364
116 ρ-選擇性鳥嘌呤交換因子akap13介導應力纖維形成(B) 10 1 0.1364
117 il22可溶性受體信號傳導路徑(B) 10 1 0.1364
118 維生素D (促鈣醇)代謝(R) 10 1 0.1364
119 間隙接合點(K) 88 3 0.14
120 范康尼氏(Fanconi)貧血路徑(N) 45 2 0.1417
121 突觸後分化中之聚集蛋白(B) 45 2 0.1417
122 TNF受體信號傳導路徑(N) 46 2 0.1467
123 C型凝集素受體(CLR) (R) 139 4 0.1486
124 牛膽素及次牛磺酸代謝(K) 11 1 0.149
125 粒線體鐵-硫集群生物合成(R) 11 1 0.149
126 中心體處之蛋白激酶(B) 11 1 0.149
127 α6 β4整合素-配位體相互作用(N) 11 1 0.149
128 I類MHC介導之抗原處理及代表(R) 191 5 0.1507
129 胰島素信號傳導路徑(K) 140 4 0.1513
130 Hedgehog信號傳導路徑(K) 47 2 0.1518
131 由Gli蛋白質介導之Hedgehog信號傳導事件(N) 48 2 0.1569
132 胺糖及核苷酸糖代謝(K) 48 2 0.1569
133 II型糖尿病(K) 48 2 0.1569
134 神經傳遞素受體及突觸後信號傳送(R) 143 4 0.1596
135 壽命調節路徑(K) 94 3 0.1606
136 gpcr信號傳導之衰減(B) 12 1 0.1614
137 藉由轉錄調節因子dream壓制疼痛感覺(B) 12 1 0.1614
138 分支鏈胺基酸分解代解(R) 12 1 0.1614
139 有絲分裂及染色體動態中之akap95作用(B) 12 1 0.1614
140 磷脂酶c-ε路徑(B) 12 1 0.1614
141 信號調節蛋白家族相互作用(R) 12 1 0.1614
142 GPVI介導之活化級聯(R) 49 2 0.162
143 磷脂酶D信號傳導路徑(K) 144 4 0.1623
144 卵巢類固醇生成(K) 50 2 0.1671
145 乳癌(K) 146 4 0.168
146 組織胺H1受體介導之信號傳導路徑(P) 13 1 0.1736
147 突觸_囊泡_遷移(P) 13 1 0.1736
148 血管收縮素原至血管緊張素之代謝(R) 13 1 0.1736
149 藉由carm1之甲基轉移酶進行轉錄調節(B) 13 1 0.1736
150 組織胺H2受體介導之信號傳導路徑(P) 13 1 0.1736
151 促甲狀腺激素釋出激素受體信號傳導路徑(P) 13 1 0.1736
152 Notch信號傳導路徑(N) 52 2 0.1775
153 子宮內膜癌(K) 52 2 0.1775
154 將GLUT4易位於質膜中(R) 52 2 0.1775
155 ErbB1下游信號傳導(N) 100 3 0.1821
156 有絲分裂分裂末期/細胞質分裂(R) 14 1 0.1857
157 黑素生成(K) 101 3 0.1857
158 凝血脂素A2受體信號傳導(N) 54 2 0.188
159 細胞老化(K) 154 4 0.1911
160 升糖素信號傳導路徑(K) 103 3 0.1931
161 無機陽離子/陰離子及胺基酸/寡肽之轉運(R) 55 2 0.1933
162 基底細胞癌(K) 55 2 0.1933
163 促乳素受體信號傳導(R) 15 1 0.1975
164 鞘醣脂生物合成-神經節系列(K) 15 1 0.1975
165 PAR4介導之凝血酶信號傳導事件(N) 15 1 0.1975
166 脂肪細胞中脂肪分解之調節(K) 56 2 0.1986
167 神經突增生之NCAM信號傳導(R) 56 2 0.1986
168 Jak-STAT信號傳導路徑(K) 158 4 0.203
169 急性骨髓白血病(K) 57 2 0.2039
170 催產素信號傳導路徑(K) 159 4 0.206
171 Th17細胞分化(K) 107 3 0.208
172 硫胺代謝(K) 16 1 0.2092
173 akt信號傳導路徑(B) 16 1 0.2092
174 異三聚體G蛋白信號傳導路徑-Gq α及Go α介導之路徑(P) 108 3 0.2118
175 TNF信號傳導路徑(K) 110 3 0.2194
176 藉由NOTCH1進行信號傳導(R) 60 2 0.2199
177 多配體蛋白聚糖-1介導之信號傳導事件(N) 17 1 0.2207
178 經由蛋白酶活化受體(PAR)進行凝血酶信號傳導(R) 17 1 0.2207
179 朊病毒路徑(B) 17 1 0.2207
180 β5 β6 β7及β8整合素細胞表面相互作用(N) 17 1 0.2207
181 gata3參與活化th2細胞介素基因表現(B) 17 1 0.2207
182 信號擴增(R) 17 1 0.2207
183 膽鹼激導性突觸(K) 111 3 0.2232
184 VEGF信號傳導路徑(K) 61 2 0.2253
185 藉由ρ GTP酶進行信號傳導(R) 338 7 0.2289
186 代謝路徑(K) 1266 22 0.2296
187 類泛素化修飾(R) 223 5 0.2305
188 RNA聚合酶II轉錄(R) 826 15 0.2311
189 cGMP-PKG信號傳導路徑(K) 168 4 0.2336
190 信號蛋白相互作用(R) 63 2 0.2361
191 LPA受體介導之事件(N) 63 2 0.2361
192 突觸囊泡週期(K) 63 2 0.2361
193 Ras路徑(P) 63 2 0.2361
194 IL4介導之信號傳導事件(N) 64 2 0.2415
195 mTOR信號傳導路徑(N) 64 2 0.2415
196 視網膜母細胞瘤蛋白質之調節(N) 64 2 0.2415
197 囊性纖維化跨膜傳導調節蛋白(cftr)及β2腎上腺素激導性受體(b2ar)路徑(B) 19 1 0.2433
198 發炎性腸病(IBD) (K) 65 2 0.2469
199 腎素分泌物(K) 65 2 0.2469
200 藉由CD28家族共刺激(R) 65 2 0.2469
表5.b1
   FDR 節點 基因集中蛋白質之比率
101 0.337 MTOR 0.0008
102 0.337 SNAP25 0.0008
103 0.337 PGM2 0.0008
104 0.337 PRKAR2B 0.0008
105 0.337 NBN 0.0008
106 0.337 GABARAPL1,PPP3R1,PIK3CG,GNG2,MTOR 0.0161
107 0.337 TLR2,PIK3CG,GHR,LAMA4,LAMA3,THBS2,GNG2,MTOR 0.0305
108 0.337 GRK3,GNG2 0.0038
109 0.337 MAP2,MTOR 0.0038
110 0.337 SDC1,LAMA4 0.0038
111 0.337 GRIN2B,ARHGEF7,EFNB1 0.0077
112 0.337 SKP2,GABARAPL1,PIK3CG,GRM1 0.012
113 0.337 PRKAR2B 0.0009
114 0.337 FDX1 0.0009
115 0.337 SNAP25 0.0009
116 0.337 PRKAR2B 0.0009
117 0.337 IL22 0.0009
118 0.337 LRP2 0.0009
119 0.337 ADCY2,TUBB8,GRM1 0.0079
120 0.337 NBN,RFC3 0.004
121 0.337 ARHGEF7,LAMA3 0.004
122 0.337 MAP4K5,TAB2 0.0041
123 0.337 PSMD6,RPS6KA5,PPP3R1,TAB2 0.0124
124 0.337 ADO 0.001
125 0.337 FDX1 0.001
126 0.337 PRKAR2B 0.001
127 0.337 LAMA3 0.001
128 0.337 PSMD6,SKP2,HERC6,TLR2,FBXW7 0.0171
129 0.337 PRKAR2B,PIK3CG,FBP1,MTOR 0.0125
130 0.337 GRK3,LRP2 0.0042
131 0.337 IFT172,GNG2 0.0043
132 0.337 CHIT1,PGM2 0.0043
133 0.337 PIK3CG,MTOR 0.0043
134 0.337 GABRG2,GRIN2B,ADCY2,GNG2 0.0128
135 0.337 ADCY2,PIK3CG,MTOR 0.0084
136 0.337 PRKAR2B 0.0011
137 0.337 PRKAR2B 0.0011
138 0.337 PPM1K 0.0011
139 0.337 PRKAR2B 0.0011
140 0.337 PRKAR2B 0.0011
141 0.337 FYB1 0.0011
142 0.337 RHOB,PIK3CG 0.0044
143 0.337 ADCY2,PIK3CG,GRM1,MTOR 0.0129
144 0.337 GDF9,ADCY2 0.0045
145 0.337 FZD3,FZD9,PIK3CG,MTOR 0.0131
146 0.337 GNG2 0.0012
147 0.337 SNAP25 0.0012
148 0.337 AOPEP 0.0012
149 0.337 PRKAR2B 0.0012
150 0.337 GNG2 0.0012
151 0.337 GNG2 0.0012
152 0.337 SKP2,NUMB 0.0046
153 0.337 CTNNA2,PIK3CG 0.0046
154 0.337 C2CD5,TBC1D1 0.0046
155 0.337 RPS6KA5,RICTOR,MTOR 0.0089
156 0.337 KIF23 0.0013
157 0.337 FZD3,FZD9,ADCY2 0.009
158 0.337 GRK3,GNG2 0.0048
159 0.337 GATA4,PPP3R1,NBN,MTOR 0.0138
160 0.337 PPP3R1,ADCY2,FBP1 0.0092
161 0.337 SLC26A4,SLC24A1 0.0049
162 0.337 FZD3,FZD9 0.0049
163 0.337 GHR 0.0013
164 0.337 ST6GALNAC3 0.0013
165 0.337 GNG2 0.0013
166 0.337 ADCY2,PIK3CG 0.005
167 0.337 RPS6KA5,ARTN 0.005
168 0.337 IL22,PIK3CG,GHR,MTOR 0.0141
169 0.337 PIK3CG,MTOR 0.0051
170 0.337 PPP3R1,ADCY2,PIK3CG,CAMK1D 0.0142
171 0.337 PPP3R1,IL22,MTOR 0.0096
172 0.337 AK5 0.0014
173 0.337 GHR 0.0014
174 0.337 GRM1,OPRM1,GNG2 0.0097
175 0.337 RPS6KA5,TAB2,PIK3CG 0.0098
176 0.337 FBXW7,NUMB 0.0054
177 0.337 SDC1 0.0015
178 0.337 GNG2 0.0015
179 0.337 LAMA3 0.0015
180 0.337 SDC1 0.0015
181 0.337 PRKAR2B 0.0015
182 0.337 GNG2 0.0015
183 0.337 ADCY2,PIK3CG,GNG2 0.0099
184 0.337 PPP3R1,PIK3CG 0.0055
185 0.337 CYFIP1,TIAM2,SCAI,ARHGAP6,RHOB,ARHGEF7,ARHGAP20 0.0302
186 0.337 NDST4,ATP6V1G1,GLCE,CHIT1,UGT8,FDFT1,ADO,B3GALT1,EXTL3,DHRS9,ETNK1,LARGE2,DGAT2,FOLH1,AK5,SYNJ2,NADK2,PGM2,ST6GALNAC3,FBP1,LAMA3,GALNT2 0.1132
187 0.337 PSMD6,SKP2,PUM2,FBXW7,ASB17 0.0199
188 0.337 PSMD6,SKP2,RUNX2,GATA4,NR2F1,INTS14,MED10,SLU7,RICTOR,NBN,FBXW7,NR4A2,RFC3,MTOR,TAF7 0.0738
189 0.337 GATA4,PPP3R1,ADCY2,PIK3CG 0.015
190 0.337 RHOB,PLXNA2 0.0056
191 0.337 ADCY2,GNG2 0.0056
192 0.337 ATP6V1G1,SNAP25 0.0056
193 0.337 RHOB,PIK3CG 0.0056
194 0.337 OPRM1,MTOR 0.0057
195 0.337 RICTOR,MTOR 0.0057
196 0.337 SKP2,RUNX2 0.0057
197 0.337 PRKAR2B 0.0017
198 0.337 IL22,TLR2 0.0058
199 0.337 PPP3R1,CTSB 0.0058
200 0.337 RICTOR,MTOR 0.0058
表5.b2
   基因集 基因集中之數目 在清單中
201 甲狀腺激素信號傳導路徑(K) 118 3
202 神經膠瘤(K) 66 2
203 藉由過氧化體增殖物活化受體α (PPARα)調節脂質代謝(R) 119 3
204 brca1 brca2及atr在易感癌症中之作用(B) 20 1
205 類固醇生物合成(K) 20 1
206 不良磷酸化之調節(B) 20 1
207 突觸黏附樣分子(R) 20 1
208 癌症中之中央碳代謝(K) 67 2
209 介白素-17信號傳導(R) 67 2
210 糖酵解/葡糖新生(K) 67 2
211 安非他明成癮(Amphetamine addiction) (K) 68 2
212 端粒酶之調節(N) 68 2
213 介白素-20家族信號傳導(R) 21 1
214 erk1/erk2MAPK信號傳導路徑(B) 21 1
215 生長激素信號傳導路徑(B) 21 1
216 膽固醇生物合成(R) 21 1
217 Notch信號傳導路徑(P) 21 1
218 藉由1型麩胺酸受體調節ck1/cdk5 (B) 21 1
219 TCR信號傳導(R) 123 3
220 溶酶體(K) 123 3
221 細胞週期(K) 124 3
222 CDC42信號傳導事件(N) 70 2
223 斯塔明(stathmin)及乳癌對抗微管試劑具有抗性(B) 22 1
224 g蛋白家族之信號傳導路徑(B) 22 1
225 腸促胰島素合成、分泌及失活(R) 22 1
226 磷酸肌醇代謝(K) 71 2
227 膽液分泌物(K) 71 2
228 由趨化細胞素及細胞介素信號傳導路徑介導之炎症(P) 72 2
229 由Hedgehog家族介導之信號傳導事件(N) 23 1
230 不匹配修復(K) 23 1
231 不飽和脂肪酸之生物合成(K) 23 1
232 eif-4e及p70s6激酶之調節(B) 23 1
233 視覺信號轉導：Rods (N) 23 1
234 甘露糖型O-聚糖生物合成(K) 23 1
235 單純疱疹感染(K) 185 4
236 B細胞受體信號傳導路徑(K) 73 2
237 利什曼體病(Leishmaniasis) (K) 73 2
238 RAB GEF將GTP交換成RAB上之GDP (R) 73 2
239 mtor信號傳導路徑(B) 24 1
240 藉由不可分型嗜血桿菌流感進行nfkb活化(B) 24 1
241 肌生成(R) 24 1
242 Ephrin B逆向信號傳導(N) 24 1
243 生長激素受體信號傳導(R) 24 1
244 維生素消化及吸收(K) 24 1
245  G α (q)信號傳導事件(R) 188 4
246 O鍵聯之醣基化(R) 75 2
247 破骨細胞分化(K) 132 3
248 C-MYC轉錄活化之驗證目標(N) 76 2
249 甘油磷脂生物合成(R) 76 2
250 脂肪酸伸長(K) 25 1
251 非基因雄激素信號傳導(N) 25 1
252 膽酸及膽汁鹽代謝(R) 25 1
253 內源性TLR信號傳導(N) 25 1
254 Huma乳頭瘤病毒感染(K) 313 6
255 S期(R) 134 3
256 葡萄糖代謝(R) 78 2
257 細胞運動中之mcalpain及朋友(B) 26 1
258 細胞凋亡信號傳導路徑(P) 26 1
259 camp依賴性蛋白激酶pka之活化(B) 26 1
260 麻疹(K) 136 3
261 泛蛋白介導之蛋白水解(K) 137 3
262 DNA損害/端粒應力誘發的老化(R) 27 1
263 鞘醣脂生物合成-乳酸及新乳糖系列(K) 27 1
264 p38 MAPK信號傳導路徑(N) 27 1
265 肝糖代謝(R) 27 1
266 收集管道酸分泌物(K) 27 1
267 EGFR酪胺酸激酶抑制劑抗性(K) 81 2
268 異三聚體G蛋白信號傳導路徑-桿狀外片段光轉導(P) 28 1
269 光轉導(K) 28 1
270 Wnt信號傳導網絡(N) 28 1
271 顫蛋白(Reelin)信號傳導路徑(N) 28 1
272 類固醇激素之代謝(R) 28 1
273 adp核糖基化因子(B) 28 1
274 C-MYB轉錄因子網絡(N) 82 2
275 L1CAM相互作用(R) 82 2
276 Hedgehog『開啟』狀態(R) 82 2
277 局部黏附(K) 201 4
278 調節幹細胞之多能性的信號傳導路徑(K) 142 3
279 BARD1信號傳導事件(N) 29 1
280 菸鹼酸酯及菸鹼醯胺代謝(K) 29 1
281 Hippo信號傳導路徑-多物種(K) 29 1
282 埃-巴二氏病毒(Epstein-Barr virus)感染(K) 204 4
283 經由同源重組(HR)或單股退火(SSA)進行HDR (R) 85 2
284 胰島素分泌物(K) 85 2
285 CDC42活性之調節(N) 30 1
286 細胞黏附分子(CAM) (K) 145 3
287 鉀通道(R) 87 2
288 無鹼基位點(AP位點)之解析(R) 31 1
289 Aurora A信號傳導(N) 31 1
290 半乳糖代謝(K) 31 1
291 條紋肌肉收縮(R) 31 1
292 反應性含氧物種之解毒(R) 31 1
293 黏蛋白型O-聚糖生物合成(K) 31 1
294 p38 mapk信號傳導路徑(B) 31 1
295 三葉因子引發黏膜癒合(B) 31 1
296 ErbB信號傳導路徑(K) 88 2
297 ρ細胞運動信號傳導路徑(B) 32 1
298 多配體蛋白聚糖-4介導之信號傳導事件(N) 32 1
299 吞噬細胞中之ROS、RNS生產(R) 32 1
300 鐸樣受體路徑(B) 32 1
表5.c1
   P-值 FDR 節點 基因集中蛋白質之比率
201 0.2503 0.337 GATA4,PIK3CG,MTOR 0.0105
202 0.2523 0.337 PIK3CG,MTOR 0.0059
203 0.2542 0.337 TIAM2,FDFT1,MED10 0.0106
204 0.2543 0.337 NBN 0.0018
205 0.2543 0.337 FDFT1 0.0018
206 0.2543 0.337 PRKAR2B 0.0018
207 0.2543 0.337 GRIN2B 0.0018
208 0.2577 0.337 PIK3CG,MTOR 0.006
209 0.2577 0.337 RPS6KA5,TAB2 0.006
210 0.2577 0.337 PGM2,FBP1 0.006
211 0.2631 0.337 PPP3R1,GRIN2B 0.0061
212 0.2631 0.337 NBN,MTOR 0.0061
213 0.2652 0.337 IL22 0.0019
214 0.2652 0.337 RPS6KA5 0.0019
215 0.2652 0.337 GHR 0.0019
216 0.2652 0.337 FDFT1 0.0019
217 0.2652 0.337 NUMB 0.0019
218 0.2652 0.337 PRKAR2B 0.0019
219 0.2699 0.337 PSMD6,FYB1,TAB2 0.011
220 0.2699 0.337 CTSB,SLC17A5,LAPTM4B 0.011
221 0.2739 0.337 SKP2,PTTG1,PTTG2 0.0111
222 0.2739 0.337 ARHGEF7,MTOR 0.0063
223 0.2759 0.337 PRKAR2B 0.002
224 0.2759 0.337 PRKAR2B 0.002
225 0.2759 0.337 GATA4 0.002
226 0.2793 0.337 SYNJ2,PIK3CG 0.0063
227 0.2793 0.337 ADCY2,ABCB11 0.0063
228 0.2847 0.337 PIK3CG,PLCL1 0.0064
229 0.2865 0.337 LRP2 0.0021
230 0.2865 0.337 RFC3 0.0021
231 0.2865 0.337 HACD3 0.0021
232 0.2865 0.337 GHR 0.0021
233 0.2865 0.337 SLC24A1 0.0021
234 0.2865 0.337 LARGE2 0.0021
235 0.288 0.337 SKP2,TLR2,TAB2,NXF3 0.0165
236 0.2901 0.337 PPP3R1,PIK3CG 0.0065
237 0.2901 0.337 TLR2,TAB2 0.0065
238 0.2901 0.337 RIN2,SBF2 0.0065
239 0.2969 0.337 GHR 0.0021
240 0.2969 0.337 TLR2 0.0021
241 0.2969 0.337 CTNNA2 0.0021
242 0.2969 0.337 EFNB1 0.0021
243 0.2969 0.337 GHR 0.0021
244 0.2969 0.337 FOLH1 0.0021
245 0.2978 0.337 XCR1,GPR68,GRM1,GNG2 0.0168
246 0.3009 0.337 LARGE2,GALNT2 0.0067
247 0.3057 0.337 PPP3R1,TAB2,PIK3CG 0.0118
248 0.3063 0.337 MTDH,NBN 0.0068
249 0.3063 0.337 DGAT2,GPD2 0.0068
250 0.3071 0.337 HACD3 0.0022
251 0.3071 0.337 GNG2 0.0022
252 0.3071 0.337 ABCB11 0.0022
253 0.3071 0.337 TLR2 0.0022
254 0.3112 0.337 FZD3,FZD9,LAMA4,LAMA3,THBS2,MTOR 0.028
255 0.3136 0.337 PSMD6,SKP2,RFC3 0.012
256 0.317 0.337 GCKR,FBP1 0.007
257 0.3172 0.337 PRKAR2B 0.0023
258 0.3172 0.337 PIK3CG 0.0023
259 0.3172 0.337 PRKAR2B 0.0023
260 0.3216 0.337 TLR2,TAB2,PIK3CG 0.0122
261 0.3256 0.337 SKP2,UBE2G1,FBXW7 0.0122
262 0.3272 0.337 NBN 0.0024
263 0.3272 0.337 B3GALT1 0.0024
264 0.3272 0.337 TAB2 0.0024
265 0.3272 0.337 PGM2 0.0024
266 0.3272 0.337 ATP6V1G1 0.0024
267 0.3331 0.337 PIK3CG,MTOR 0.0072
268 0.337 0.337 GNG2 0.0025
269 0.337 0.337 SLC24A1 0.0025
270 0.337 0.337 FZD9 0.0025
271 0.337 0.337 GRIN2B 0.0025
272 0.337 0.337 FDX1 0.0025
273 0.337 0.337 ARHGAP6 0.0025
274 0.3384 0.3384 CD34,TAB2 0.0073
275 0.3384 0.3384 RPS6KA5,NUMB 0.0073
276 0.3384 0.3384 PSMD6,NUMB 0.0073
277 0.3407 0.3407 PIK3CG,LAMA4,LAMA3,THBS2 0.018
278 0.3456 0.3456 FZD3,FZD9,PIK3CG 0.0127
279 0.3467 0.3467 NBN 0.0026
280 0.3467 0.3467 NADK2 0.0026
281 0.3467 0.3467 FAT4 0.0026
282 0.3506 0.3506 PSMD6,SKP2,TAB2,PIK3CG 0.0182
283 0.3543 0.3543 NBN,RFC3 0.0076
284 0.3543 0.3543 ADCY2,SNAP25 0.0076
285 0.3562 0.3562 ARHGEF7 0.0027
286 0.3575 0.3575 SDC1,CD34,NLGN4X 0.013
287 0.3648 0.3648 KCNC4,GNG2 0.0078
288 0.3656 0.3656 RFC3 0.0028
289 0.3656 0.3656 ARHGEF7 0.0028
290 0.3656 0.3656 PGM2 0.0028
291 0.3656 0.3656 MYL3 0.0028
292 0.3656 0.3656 GPX7 0.0028
293 0.3656 0.3656 GALNT2 0.0028
294 0.3656 0.3656 RPS6KA5 0.0028
295 0.3656 0.3656 GHR 0.0028
296 0.3701 0.3701 PIK3CG,MTOR 0.0079
297 0.3749 0.3749 ARHGAP6 0.0029
298 0.3749 0.3749 LAMA3 0.0029
299 0.3749 0.3749 ATP6V1G1 0.0029
300 0.3749 0.3749 TLR2 0.0029
表5.c2
   基因集 基因集中之數目 在清單中
301 多配體蛋白聚糖-2介導之信號傳導事件(N) 32 1
302 減數分裂重組合(R) 32 1
303 非典型Wnt信號傳導路徑(N) 32 1
304 前列腺癌(K) 89 2
305 ABC家族蛋白質介導之轉運(R) 89 2
306 轉譯後修飾:合成GPI錨定蛋白質(R) 89 2
307 Rap1信號傳導路徑(K) 212 4
308 擴張型心肌症(K) 90 2
309 粒線體生物合成(R) 90 2
310 類風濕性關節炎(K) 90 2
311 果糖及甘露糖代謝(K) 33 1
312 α4 β1整合素信號傳導事件(N) 33 1
313 由MAPK路徑介導之Trk受體信號傳導(N) 33 1
314 氧化氮在心臟中之作用(B) 33 1
315 鹼基切除修復(K) 33 1
316 神經活性配體-受體相互作用(K) 278 5
317 FGF信號傳導路徑(P) 92 2
318 IL1介導之信號傳導事件(N) 34 1
319 ATM路徑(N) 34 1
320 Hippo信號傳導路徑(K) 154 3
321 Fc γ R介導之噬菌作用(K) 93 2
322 由PI3K介導之IL2信號傳導事件(N) 35 1
323 丙胺酸、天冬胺酸及麩胺酸代謝(K) 35 1
324 非洲錐蟲病(K) 35 1
325 由p38-α及p38-β介導之信號傳導(N) 35 1
326 NF-κ B信號傳導路徑(K) 95 2
327 甘油磷脂代謝(K) 95 2
328 整合素信號傳導路徑(P) 158 3
329 非同源性末端接合(NHEJ) (R) 36 1
330 過氧化體增殖物經由ppara調節基因的機制(B) 36 1
331 藉由碳水化合物及camp進行chrebp調節(B) 36 1
332 DNA複製(K) 36 1
333 RET信號傳導(R) 36 1
334 澱粉及蔗糖代謝(K) 36 1
335 藉由NGF進行信號傳導(R) 159 3
336 造血細胞譜系(K) 97 2
337 AP1家庭成員Fra1及Fra2之驗證轉錄目標(N) 37 1
338 rac1細胞運動信號傳導路徑(B) 37 1
339 ErbB2/ErbB3信號傳導事件(N) 37 1
340 孕酮介導之卵母細胞成熟(K) 98 2
341 DNA合成(R) 98 2
342 磷脂醯環己六醇信號傳導系統(K) 99 2
343 TRP通道之發炎性介體調節(K) 99 2
344 TNF信號傳導(R) 38 1
345 核苷酸結合域，含有富含白胺酸重複序列之受體(NLR)信號傳導路徑(R) 38 1
346 由II類HDAC介導之信號傳導事件(N) 38 1
347 EPHB正向信號傳導(N) 38 1
348 端粒維持(R) 38 1
349 經醛固酮調節的鈉再吸收(K) 39 1
350 癌症中之膽鹼代謝(K) 101 2
351 IFN-γ路徑(N) 40 1
352 Aurora B信號傳導(N) 40 1
353 mTOR信號傳導(R) 40 1
354 神經傳遞素釋放週期(R) 40 1
355 C/3類(代謝型麩胺酸/費洛蒙受體) (R) 40 1
356 自噬(K) 40 1
357 HIF-1信號傳導路徑(K) 103 2
358 卻格司氏病(Chagas disease) (美國錐蟲病) (K) 104 2
359 細胞凋亡之內在路徑(R) 41 1
360 膀胱癌(K) 41 1
361 藉由camp依賴性蛋白激酶活化csk抑制經由t細胞受體之信號傳導(B) 41 1
362 BMP受體信號傳導(N) 41 1
363 脂肪消化及吸收(K) 41 1
364 藉由EGFR進行信號傳導(R) 41 1
365 同源重組(K) 41 1
366 NOD樣受體信號傳導路徑(K) 170 3
367 T細胞受體信號傳導路徑(K) 105 2
368 RNA轉運(K) 171 3
369 質膜雌激素受體信號傳導(N) 42 1
370 葡糖胺聚糖代謝(R) 106 2
371 心肌導電(R) 107 2
372 藉由ERBB4進行信號傳導(R) 43 1
373 嘌呤代謝(K) 175 3
374 抗胰島素症(K) 109 2
375 DAP12相互作用(R) 44 1
376 蛋白酶體(K) 44 1
377 介白素-4及介白素-13信號傳導(R) 110 2
378 ABC轉運體(K) 45 1
379 DNA雙股斷裂應答(R) 45 1
380 DNA損害旁通(R) 45 1
381 ρA信號傳導路徑(N) 45 1
382 醚脂質代謝(K) 45 1
383 δNp63同功型之驗證轉錄目標(N) 45 1
384 基礎轉錄因子(K) 45 1
385 Cilium組裝(R) 179 3
386 結核病(K) 179 3
387 碳水化合物消化及吸收(K) 46 1
388 ρA活性之調節(N) 46 1
389 FGF信號傳導路徑(N) 47 1
390 核苷酸切除修復(K) 47 1
391 IL6介導之信號傳導事件(N) 47 1
392 血管新生中之整合素(N) 47 1
393 TGF-β受體信號傳導(N) 47 1
394 鞘脂代謝(K) 47 1
395 鈣信號傳導路徑(K) 182 3
表5.d1
   P值 FDR 節點 基因集中蛋白質之比率
301 0.3749 0.3749 LAMA3 0.0029
302 0.3749 0.3749 NBN 0.0029
303 0.3749 0.3749 TAB2 0.0029
304 0.3753 0.3753 PIK3CG,MTOR 0.008
305 0.3753 0.3753 PSMD6,DERL1 0.008
306 0.3753 0.3753 CD109,MDGA1 0.008
307 0.3772 0.3772 GRIN2B,ADCY2,DOCK4,PIK3CG 0.019
308 0.3805 0.3805 MYL3,ADCY2 0.008
309 0.3805 0.3805 TFB1M,SIRT5 0.008
310 0.3805 0.3805 ATP6V1G1,TLR2 0.008
311 0.384 0.384 FBP1 0.0029
312 0.384 0.384 THBS2 0.0029
313 0.384 0.384 RPS6KA5 0.0029
314 0.384 0.384 PRKAR2B 0.0029
315 0.384 0.384 NEIL2 0.0029
316 0.3861 0.3861 GABRG2,GRIN2B,GRM1,GHR,OPRM1 0.0249
317 0.3908 0.3908 PIK3CG,PPP6C 0.0082
318 0.393 0.393 TAB2 0.003
319 0.393 0.393 NBN 0.003
320 0.3932 0.3932 FZD3,FZD9,CTNNA2 0.0138
321 0.396 0.396 AMPH,PIK3CG 0.0083
322 0.4018 0.4018 MTOR 0.0031
323 0.4018 0.4018 FOLH1 0.0031
324 0.4018 0.4018 LAMA4 0.0031
325 0.4018 0.4018 RPS6KA5 0.0031
326 0.4062 0.4062 TAB2,LBP 0.0085
327 0.4062 0.4062 ETNK1,GPD2 0.0085
328 0.4089 0.4089 RHOB,ELMO2,PIK3CG 0.0141
329 0.4106 0.4106 NBN 0.0032
330 0.4106 0.4106 NR2F1 0.0032
331 0.4106 0.4106 PRKAR2B 0.0032
332 0.4106 0.4106 RFC3 0.0032
333 0.4106 0.4106 ARTN 0.0032
334 0.4106 0.4106 PGM2 0.0032
335 0.4128 0.4128 RPS6KA5,TIAM2,ARHGEF7 0.0142
336 0.4164 0.4164 CD34,CD59 0.0087
337 0.4192 0.4192 LAMA3 0.0033
338 0.4192 0.4192 ARHGAP6 0.0033
339 0.4192 0.4192 MTOR 0.0033
340 0.4214 0.4214 ADCY2,PIK3CG 0.0088
341 0.4214 0.4214 PSMD6,RFC3 0.0088
342 0.4264 0.4264 SYNJ2,PIK3CG 0.0088
343 0.4264 0.4264 ADCY2,PIK3CG 0.0088
344 0.4277 0.4277 TAB2 0.0034
345 0.4277 0.4277 TAB2 0.0034
346 0.4277 0.4277 GNG2 0.0034
347 0.4277 0.4277 EFNB1 0.0034
348 0.4277 0.4277 RFC3 0.0034
349 0.436 0.436 PIK3CG 0.0035
350 0.4364 0.4364 PIK3CG,MTOR 0.009
351 0.4443 0.4443 MTOR 0.0036
352 0.4443 0.4443 KIF23 0.0036
353 0.4443 0.4443 MTOR 0.0036
354 0.4443 0.4443 SNAP25 0.0036
355 0.4443 0.4443 GRM1 0.0036
356 0.4443 0.4443 GABARAPL1 0.0036
357 0.4463 0.4463 PIK3CG,MTOR 0.0092
358 0.4512 0.4512 TLR2,PIK3CG 0.0093
359 0.4524 0.4524 PPP3R1 0.0037
360 0.4524 0.4524 RPS6KA5 0.0037
361 0.4524 0.4524 PRKAR2B 0.0037
362 0.4524 0.4524 TAB2 0.0037
363 0.4524 0.4524 DGAT2 0.0037
364 0.4524 0.4524 ARHGEF7 0.0037
365 0.4524 0.4524 NBN 0.0037
366 0.4551 0.4551 GABARAPL1,CTSB,TAB2 0.0152
367 0.4561 0.4561 PPP3R1,PIK3CG 0.0094
368 0.4589 0.4589 CYFIP1,SUMO4,NXF3 0.0153
369 0.4604 0.4604 GNG2 0.0038
370 0.4609 0.4609 GLCE,SDC1 0.0095
371 0.4658 0.4658 GATA4,KCNIP4 0.0096
372 0.4683 0.4683 TAB2 0.0038
373 0.474 0.474 ADCY2,AK5,PGM2 0.0156
374 0.4753 0.4753 PIK3CG,MTOR 0.0097
375 0.476 0.476 TREM1 0.0039
376 0.476 0.476 PSMD6 0.0039
377 0.4801 0.4801 LBP,OPRM1 0.0098
378 0.4837 0.4837 ABCB11 0.004
379 0.4837 0.4837 NBN 0.004
380 0.4837 0.4837 RFC3 0.004
381 0.4837 0.4837 SCAI 0.004
382 0.4837 0.4837 UGT8 0.004
383 0.4837 0.4837 FBXW7 0.004
384 0.4837 0.4837 TAF7 0.004
385 0.4889 0.4889 IFT172,PRKAR2B,MKKS 0.016
386 0.4889 0.4889 PPP3R1,TLR2,LBP 0.016
387 0.4912 0.4912 PIK3CG 0.0041
388 0.4912 0.4912 ARHGAP6 0.0041
389 0.4987 0.4987 RUNX2 0.0042
390 0.4987 0.4987 RFC3 0.0042
391 0.4987 0.4987 LBP 0.0042
392 0.4987 0.4987 SDC1 0.0042
393 0.4987 0.4987 TAB2 0.0042
394 0.4987 0.4987 UGT8 0.0042
395 0.4999 0.4999 PPP3R1,ADCY2,GRM1 0.0163
表5.d2
   基因集 基因集中之數目 在清單中 P值
1 癌症中之路徑(K) 397 19 0.0000204
2 Huma乳頭瘤病毒感染(K) 313 15 0.000155
3 基底細胞癌(K) 55 6 0.000270
4 PI3K-Akt信號傳導路徑(K) 341 15 0.000382
5 弓蟲病(K) 118 8 0.000646
6 胰島素路徑(N) 45 5 0.000812
7 G α (i)信號傳導事件(R) 345 14 0.00129
8 ECM-受體相互作用(K) 82 6 0.00210
9 IL8及CXCR2介導之信號傳導事件(N) 34 4 0.00222
10 蛋白質修復(R) 5 2 0.00295
11 5HT1型受體介導之信號傳導路徑(P) 19 3 0.00357
12 I類MHC介導之抗原處理及代表(R) 191 9 0.00363
13 局部黏附(K) 201 9 0.00504
14 癌症中之蛋白多醣(K) 205 9 0.00570
15 黑素生成(K) 101 6 0.00574
16 突觸後分化中之聚集蛋白(B) 45 4 0.00596
17 NOD樣受體信號傳導路徑(K) 170 8 0.00603
18 5HT4型受體介導之信號傳導路徑(P) 23 3 0.00605
19 麻疹(K) 136 7 0.00628
20 TGF-β受體信號傳導(N) 47 4 0.00693
21 Wnt信號傳導路徑(K) 143 7 0.00815
22 阿茲海默症(Alzheimer disease)-早老素路徑(P) 111 6 0.00890
23 藉由PDGF進行信號傳導(R) 51 4 0.00915
24 β-連環蛋白非依賴性WNT信號傳導(R) 112 6 0.00927
25 β1腎上腺素激導性受體信號傳導路徑(P) 27 3 0.00935
26 將GLUT4易位於質膜中(R) 52 4 0.00977
27 Wnt信號傳導網絡(N) 28 3 0.0103
28 IL8及CXCR1介導之信號傳導事件(N) 28 3 0.0103
29 Hedgehog信號傳導路徑(P) 10 2 0.0112
30 mTOR信號傳導路徑(K) 154 7 0.0119
31 TCR信號傳導(R) 123 6 0.0141
32 G蛋白β：γ信號傳導(R) 32 3 0.0147
33 膽鹼分解代解(R) 1 1 0.0157
34 能量代謝之整合(R) 92 5 0.0161
35 藉由VEGF進行信號傳導(R) 94 5 0.0175
36 CXCR3介導之信號傳導事件(N) 35 3 0.0186
37 非洲錐蟲病(K) 35 3 0.0186
38 Rap1信號傳導路徑(K) 212 8 0.0204
39 阿米巴病(K) 98 5 0.0205
40 β1整合素細胞表面相互作用(N) 66 4 0.0214
41 鈣黏蛋白信號傳導路徑(P) 100 5 0.0221
42 C型凝集素受體(CLR) (R) 139 6 0.024
43 經醛固酮調節的鈉再吸收(K) 39 3 0.0246
44 FOXM1轉錄因子網絡(N) 40 3 0.0262
45 配體依賴性凋亡蛋白酶激活(R) 16 2 0.027
46 Wnt信號傳導路徑(P) 267 9 0.0272
47 鐸樣受體信號傳導路徑(K) 106 5 0.0275
48 由趨化細胞素及細胞介素信號傳導路徑介導之炎症(P) 72 4 0.0283
49 利什曼體病(K) 73 4 0.0295
50 B型肝炎(K) 146 6 0.0296
51 乳癌(K) 146 6 0.0296
52 FOXA1轉錄因子網絡(N) 42 3 0.0297
53 鉑耐藥性(K) 75 4 0.0321
54 δNp63同功型之驗證轉錄目標(N) 45 3 0.0353
55 整合素相關激酶信號傳導(N) 45 3 0.0353
56 Hippo信號傳導路徑(K) 154 6 0.0368
57 淋巴球中之經鈣調神經磷酸酶調節的NFAT依賴性轉錄(N) 46 3 0.0373
58 CXCR4介導之信號傳導事件(N) 80 4 0.0392
59 由Gli蛋白質介導之Hedgehog信號傳導事件(N) 48 3 0.0414
60 Hedgehog『開啟』狀態(R) 82 4 0.0422
61 瘧疾(K) 49 3 0.0436
62 β2腎上腺素激導性受體信號傳導路徑(P) 21 2 0.0442
63 β3腎上腺素激導性受體信號傳導路徑(P) 21 2 0.0442
64 催產素受體介導之信號傳導路徑(P) 21 2 0.0442
65 GABA-B_受體_II_信號傳導(P) 3 1 0.0464
66 胰島素分泌物(K) 85 4 0.047
67 細胞週期(K) 124 5 0.0483
68 EPH-Ephrin信號傳導(R) 86 4 0.0487
69 子宮內膜癌(K) 52 3 0.0503
70 G α (z)信號傳導事件(R) 23 2 0.052
71 不匹配修復(K) 23 2 0.052
72 前列腺癌(K) 89 4 0.0539
73 嗎啡鹼成癮(K) 91 4 0.0576
74 介白素-12家族信號傳導(R) 55 3 0.0576
75 內源性TLR信號傳導(N) 25 2 0.0602
76 促腎上腺皮質激素釋出因子受體信號傳導路徑(P) 25 2 0.0602
77 蛋白聚糖多配體蛋白聚糖介導之信號傳導事件(N) 4 1 0.0613
78 藉由ps1產生澱粉樣b-肽(B) 4 1 0.0613
79 半乳糖分解代解(R) 4 1 0.0613
80 ifn γ信號傳導路徑(B) 4 1 0.0613
81 軸突導引(K) 177 6 0.0636
82 5HT2型受體介導之信號傳導路徑(P) 26 2 0.0644
83 ALK1信號傳導事件(N) 26 2 0.0644
84 類泛素化修飾(R) 223 7 0.0655
85 晝夜節律(K) 96 4 0.0672
86 CD4+ TCR路徑中之鈣信號傳導(N) 27 2 0.0688
87 VEGFR1特定信號(N) 27 2 0.0688
88 整合素信號傳導(R) 27 2 0.0688
89 嗜中性白血球脫粒(R) 418 11 0.0696
90 由局部黏著斑激酶介導之信號傳導事件(N) 60 3 0.0707
91 神經營養因子介導之Trk受體信號傳導(N) 60 3 0.0707
92 孕酮介導之卵母細胞成熟(K) 98 4 0.0713
93 胰島素信號傳導路徑(K) 140 5 0.0729
94 雌激素信號傳導路徑(K) 100 4 0.0755
95 PLK3信號傳導事件(N) 5 1 0.0761
96 調節幹細胞之多能性的信號傳導路徑(K) 142 5 0.0764
97 趨化細胞素信號傳導路徑(K) 187 6 0.0781
98 神經傳遞素受體及突觸後信號傳送(R) 143 5 0.0782
99 Hedgehog配體生物合成(R) 63 3 0.0792
100 細胞黏附分子(CAM) (K) 145 5 0.0818
101 升糖素信號傳導路徑(K) 103 4 0.0821
102 mTOR信號傳導路徑(N) 64 3 0.0821
103 檸檬酸鹽循環(TCA循環) (K) 30 2 0.0824
104 卻格司氏病(美國錐蟲病) (K) 104 4 0.0843
105 發炎性腸病(IBD) (K) 65 3 0.0851
106 藉由CD28家族進行共刺激(R) 65 3 0.0851
107 神經配蛋白受體失調蛋白質-1控制erbb3受體再循環(B) 6 1 0.0906
108 e2f1分解路徑(B) 6 1 0.0906
109 磷脂肌醇蛋白聚醣3網絡(N) 6 1 0.0906
110 丙酸酯代謝(K) 32 2 0.0919
表6.a1
   FDR 節點 基因集中蛋白質之比率
1 0.0119 CBLB,FZD3,FZD9,GLI3,SHH,PLCB1,ADCY2,CTNNA2,PGF,MSH2,WNT2,CDK6,FGF12,FGFR2,CCNA1,LAMA4,LAMA3,GNG2,TCF7L2 0.0355
2 0.0453 FZD3,FZD9,COL9A1,IKBKE,MAGI1,WNT2,CDK6,DLG2,CCNA1,COL6A1,CREB5,LAMA4,LAMA3,THBS2,TCF7L2 0.028
3 0.0527 FZD3,FZD9,GLI3,SHH,WNT2,TCF7L2 0.0049
4 0.0557 COL9A1,SGK1,TLR4,PGF,CDK6,FGF12,FGFR2,GHR,PDPK1,COL6A1,CREB5,LAMA4,LAMA3,THBS2,GNG2 0.0305
5 0.0755 IL12B,IFNGR1,TLR4,LY96,TAB2,PDPK1,LAMA4,LAMA3 0.0105
6 0.0788 RAPGEF1,SGK1,RHOQ,EXOC2,PDPK1 0.004
7 0.1067 GPR183,SDC1,GPR18,OXGR1,PLCB1,ADCY2,CCL20,STRA6,PDE4B,OPRM1,SSTR1,CX3CR1,GNG2,METAP2 0.0308
8 0.1444 COL9A1,SDC1,COL6A1,LAMA4,LAMA3,THBS2 0.0073
9 0.1444 PLCB1,ELMO1,PDPK1,GNG2 0.003
10 0.1713 MSRA,MSRB2 0.0004
11 0.1744 ADCY2,SNAP23,GNG2 0.0017
12 0.1744 HERC5,PSMD6,HERC6,NEDD4L,TLR4,PSMB2,FBXW2,LY96,SNAP23 0.0171
13 0.1885 COL9A1,RAPGEF1,PAK3,PGF,PDPK1,COL6A1,LAMA4,LAMA3,THBS2 0.018
14 0.1885 CBLB,IL12B,FZD3,FZD9,SDC1,SHH,TLR4,WNT2,PDPK1 0.0183
15 0.1885 FZD3,FZD9,PLCB1,ADCY2,WNT2,TCF7L2 0.009
16 0.1885 ARHGEF7,PAK3,NRG3,LAMA3 0.004
17 0.1885 GABARAPL1,IKBKE,PLCB1,TLR4,TAB2,CASP4,AIM2,IFI16 0.0152
18 0.1885 ADCY2,SNAP23,GNG2 0.0021
19 0.1885 CBLB,IL12B,IKBKE,IFNGR1,TLR4,CDK6,TAB2 0.0122
20 0.2009 NEDD4L,FKBP1A,TAB2,PDPK1 0.0042
21 0.2062 SFRP5,FZD3,FZD9,PLCB1,PRICKLE2,WNT2,TCF7L2 0.0128
22 0.2062 FZD3,FZD9,CTNNA2,WNT2,ACTR2,TCF7L2 0.0099
23 0.2062 COL9A1,RAPGEF1,COL6A1,THBS2 0.0046
24 0.2062 PSMD6,FZD3,PLCB1,PSMB2,GNG2,TCF7L2 0.01
25 0.2062 ADCY2,SNAP23,GNG2 0.0024
26 0.2062 RHOQ,EXOC2,SNAP23,TBC1D1 0.0046
27 0.2062 FZD9,WNT2,ATP6AP2 0.0025
28 0.2062 PLCB1,PDPK1,GNG2 0.0025
29 0.2244 GLI3,SHH 0.0009
30 0.2257 ATP6V1E2,FZD3,FZD9,SGK1,RICTOR,WNT2,PDPK1 0.0138
31 0.2545 PSMD6,FYB1,PSMB2,PAK3,TAB2,PDPK1 0.011
32 0.2647 PLCB1,PDPK1,GNG2 0.0029
33 0.2669 SLC44A1 0.0001
34 0.2738 KCNC2,RAPGEF4,ADCY2,AKAP5,GNG2 0.0082
35 0.2789 RICTOR,PAK3,PGF,ELMO1,PDPK1 0.0084
36 0.2789 RICTOR,PDPK1,GNG2 0.0031
37 0.2789 IL12B,PLCB1,LAMA4 0.0031
38 0.3001 RAPGEF1,PLCB1,RAPGEF4,ADCY2,MAGI1,PGF,FGF12,FGFR2 0.019
39 0.3001 IL12B,PLCB1,TLR4,LAMA4,LAMA3 0.0088
40 0.3001 COL6A1,LAMA4,LAMA3,THBS2 0.0059
41 0.3007 FZD3,FZD9,CTNNA2,WNT2,CDH17 0.0089
42 0.3007 PSMD6,PSMB2,PAK3,CLEC7A,TAB2,PDPK1 0.0124
43 0.3007 NEDD4L,SGK1,PDPK1 0.0035
44 0.3007 CHEK2,CCNB2,LAMA4 0.0036
45 0.3007 TLR4,LY96 0.0014
46 0.3007 SFRP5,FZD3,FZD9,PLCB1,CTNNA2,WNT2,CDH17,GNG2,TCF7L2 0.0239
47 0.3007 IL12B,IKBKE,TLR4,LY96,TAB2 0.0095
48 0.3007 PLCB1,CCL20,PDPK1,COL6A1 0.0064
49 0.3007 IL12B,IFNGR1,TLR4,TAB2 0.0065
50 0.3007 EGR3,IKBKE,TLR4,CDK6,CCNA1,CREB5 0.0131
51 0.3007 FZD3,FZD9,WNT2,CDK6,FGF12,TCF7L2 0.0131
52 0.3007 NR2F2,SHH,DSCAM 0.0038
53 0.3007 GSTO2,GSTO1,MSH2,PDPK1 0.0067
54 0.3007 HBP1,RAB38,CCNB2 0.004
55 0.3007 TNS1,ARHGEF7,RICTOR 0.004
56 0.3007 FZD3,FZD9,CTNNA2,WNT2,DLG2,TCF7L2 0.0138
57 0.3007 CBLB,EGR3,IRF4 0.0041
58 0.3007 PLCB1,RICTOR,PDPK1,GNG2 0.0072
59 0.3007 GLI3,SHH,GNG2 0.0043
60 0.3007 PSMD6,GLI3,SHH,PSMB2 0.0073
61 0.3007 SDC1,TLR4,THBS2 0.0044
62 0.3007 SNAP23,GNG2 0.0019
63 0.3007 SNAP23,GNG2 0.0019
64 0.3007 SNAP23,GNG2 0.0019
65 0.3007 ADCY2 0.0003
66 0.3007 PLCB1,RAPGEF4,ADCY2,CREB5 0.0076
67 0.3007 CHEK2,PTTG2,CCNB2,CDK6,CCNA1 0.0111
68 0.3007 ARHGEF7,PAK3,ADAM10,ACTR2 0.0077
69 0.3007 CTNNA2,PDPK1,TCF7L2 0.0046
70 0.3007 ADCY2,GNG2 0.0021
71 0.3007 MSH2,RFC3 0.0021
72 0.3007 FGFR2,PDPK1,CREB5,TCF7L2 0.008
73 0.3007 ADCY2,PDE4B,OPRM1,GNG2 0.0081
74 0.3007 IL12B,GSTO1,LCP1 0.0049
75 0.3007 TLR4,LY96 0.0022
76 0.3007 SNAP23,GNG2 0.0022
77 0.3007 SDC1 0.0004
78 0.3007 ADAM10 0.0004
79 0.3007 PGM2 0.0004
80 0.3007 IFNGR1 0.0004
81 0.3007 PDK1,FZD3,SHH,PAK3,SRGAP3,SRGAP2 0.0158
82 0.3007 SNAP23,GNG2 0.0023
83 0.3007 FKBP1A,INHBA 0.0023
84 0.3007 PSMD6,PUM2,PSMB2,KCTD6,FBXW2,TULP4,ASB17 0.0199
85 0.3007 PLCB1,ADCY2,GUCY1A2,GNG2 0.0086
86 0.3007 AKAP5,FKBP1A 0.0024
87 0.3007 PGF,PDPK1 0.0024
88 0.3007 RAPGEF4,PDPK1 0.0024
89 0.3007 PSMD6,OLR1,CD58,FRK,ADAM10,SNAP23,PGM2,ACTR2,ATP6AP2,LTF,VAPA 0.0374
90 0.3007 RAPGEF1,ARHGEF7,ELMO1 0.0054
91 0.3007 NEDD4L,RAPGEF1,ELMO1 0.0054
92 0.3007 CPEB4,ADCY2,CCNB2,CCNA1 0.0088
93 0.3007 CBLB,PPP1R3D,RAPGEF1,RHOQ,PDPK1 0.0125
94 0.3007 PLCB1,ADCY2,OPRM1,CREB5 0.0089
95 0.3007 CHEK2 0.0004
96 0.3007 FZD3,FZD9,WNT2,INHBA,FGFR2 0.0127
97 0.3007 PLCB1,ADCY2,CCL20,ELMO1,CX3CR1,GNG2 0.0167
98 0.3007 PLCB1,ADCY2,AKAP5,PDPK1,GNG2 0.0128
99 0.3007 PSMD6,SHH,PSMB2 0.0056
100 0.3007 ALCAM,SDC1,CD58,CNTNAP2,NLGN4Y 0.013
101 0.3007 LDHAL6B,PLCB1,ADCY2,CREB5 0.0092
102 0.3007 SGK1,RICTOR,PDPK1 0.0057
103 0.3007 SUCLG2,DLST 0.0027
104 0.3007 IL12B,IFNGR1,PLCB1,TLR4 0.0093
105 0.3007 IL12B,IFNGR1,TLR4 0.0058
106 0.3007 RICTOR,PAK3,PDPK1 0.0058
107 0.3007 NRG3 0.0005
108 0.3007 CCNA1 0.0005
109 0.3007 SHH 0.0005
110 0.3007 SUCLG2,LDHAL6B 0.0029
表6.a2
   基因集 基因集中之數目 在清單中
111 異三聚體G蛋白信號傳導路徑-Gq α及Go α介導之路徑(P) 108 4
112 p53信號傳導路徑(K) 69 3
113 細胞週期檢查點(R) 246 7
114 吞噬體(K) 154 5
115 cAMP信號傳導路徑(K) 200 6
116 藉由分解複合物分解β-連環蛋白(R) 70 3
117 膽鹼激導性突觸(K) 111 4
118 囊泡轉運中之SNARE相互作用(K) 34 2
119 ErbB1之內化(N) 35 2
120 由Akt介導之I類PI3K信號傳導事件(N) 35 2
121 PPAR信號傳導路徑(K) 72 3
122 心律不整右心室心肌病(ARVC) (K) 72 3
123 整合素信號傳導路徑(P) 158 5
124 藉由細胞色素P450代謝異生物質(K) 74 3
125 藉由胰島素受體進行信號傳導(R) 74 3
126 甲狀腺激素合成(K) 74 3
127 檸檬酸(TCA)循環及呼吸道電子轉運(R) 162 5
128 血小板凝集(栓塞形成) (R) 37 2
129 ATR信號傳導路徑(N) 37 2
130 HTLV-I感染(K) 258 7
131 音蝟因子受體ptc1調節細胞週期(B) 8 1
132 伴隨蛋白調節干擾素信號傳導路徑(B) 8 1
133 快速糖皮質激素信號傳導(N) 8 1
134 百日咳(K) 76 3
135 RAC1活性之調節(N) 38 2
136 核苷酸結合域，含有富含白胺酸重複序列之受體(NLR)信號傳導路徑(R) 38 2
137 胞外基質組織(R) 261 7
138 上皮細胞之細菌侵入(K) 78 3
139 血小板活化(K) 122 4
140 IFN-γ路徑(N) 40 2
141 I類PI3K信號傳導事件(N) 40 2
142 磷酸戊糖路徑(單磷酸己糖分流) (R) 9 1
143 由肝細胞生長因子受體(c-Mct)介導之信號傳導事件(N) 80 3
144 AMPK信號傳導路徑(K) 124 4
145 卵母細胞減數分裂(K) 124 4
146 藉由EGFR進行信號傳導(R) 41 2
147 化學癌發生(K) 82 3
148 C-MYB轉錄因子網絡(N) 82 3
149 醛固酮合成及分泌(K) 82 3
150 PIP3活化AkT信號傳導(R) 222 6
151 質膜雌激素受體信號傳導(N) 42 2
152 nk細胞中之no2依賴性il-12路徑(B) 10 1
153 5HT3型受體介導之信號傳導路徑(P) 10 1
154 g-分泌酶介導之erbb4信號傳導路徑(B) 10 1
155 VEGF及VEGFR信號傳導網絡(N) 10 1
156 PAR1介導之凝血酶信號傳導事件(N) 43 2
157 β3整合素細胞表面相互作用(N) 43 2
158 鬆弛素信號傳導路徑(K) 130 4
159 經由同源重組(HR)或單股退火(SSA)進行HDR (R) 85 3
160 有絲分裂G2-G2/M期(R) 178 5
161 蛋白酶體(K) 44 2
162 小細胞肺癌(K) 86 3
163 Ras信號傳導路徑(K) 229 6
164 有絲分裂G1-G1/S期(R) 132 4
165 卡波西氏肉瘤相關疱疹病毒感染(K) 180 5
166 反高爾基體網絡囊泡出芽(R) 45 2
167 ALK2信號傳導事件(N) 11 1
168 組胺酸、離胺酸、苯丙胺酸、酪胺酸、脯胺酸及色胺酸分解代解(R) 11 1
169 α6 β4整合素-配位體相互作用(N) 11 1
170 沙門氏菌如何劫持細胞(B) 11 1
171 鉀通道(R) 87 3
172 ErbB信號傳導路徑(K) 88 3
173 GABA能突觸(K) 88 3
174 間隙接合點(K) 88 3
175 FoxO信號傳導路徑(K) 134 4
176 TNF受體信號傳導路徑(N) 46 2
177 轉譯後修飾:合成GPI錨定蛋白質(R) 89 3
178 MAPK6/MAPK4信號傳導(R) 89 3
179 藉由ρ GTP酶進行信號傳導(R) 338 8
180 Apelin信號傳導路徑(K) 136 4
181 FGF信號傳導路徑(N) 47 2
182 Hedgehog信號傳導路徑(K) 47 2
183 介白素-10信號傳導(R) 47 2
184 單純疱疹感染(K) 185 5
185 Hedgehog『關閉』狀態(R) 90 3
186 蛋白質消化及吸收(K) 90 3
187 類風濕性關節炎(K) 90 3
188 唾液分泌物(K) 90 3
189 藉由NOTCH4進行信號傳導(R) 12 1
190 雌激素反應性蛋白質efp控制細胞週期及乳房腫瘤生長(B) 12 1
191 肽激素生物合成(R) 12 1
192 信號調節蛋白家族相互作用(R) 12 1
193 胺糖及核苷酸糖類代謝(K) 48 2
194 黏附接合穩定性及解組裝之轉譯後調節(N) 48 2
195 流體剪應力及動脈粥樣硬化(K) 139 4
196 TAp63同功型之驗證轉錄目標(N) 49 2
197 IL-17信號傳導路徑(K) 93 3
198 組織胺H1受體介導之信號傳導路徑(P) 13 1
199 纖維蛋白溶解路徑(B) 13 1
200 血管收縮素原至血管緊張素之代謝(R) 13 1
201 組織胺H2受體介導之信號傳導路徑(P) 13 1
202 藉由活化素進行信號傳導(R) 13 1
203 促甲狀腺激素釋出激素受體信號傳導路徑(P) 13 1
204 th1發育中il12及stat4依賴性信號傳導路徑(B) 13 1
205 卵巢類固醇生成(K) 50 2
206 軸突蛋白及神經配蛋白(R) 50 2
207 NF-κ B信號傳導路徑(K) 95 3
208 鐸樣受體級聯(R) 143 4
209 藉由1型類胰島素生長因子1受體(IGF1R)進行信號傳導(R) 51 2
210 胰臟分泌物(K) 96 3
211 離子通道轉運(R) 145 4
212 過氧化體脂質代謝(R) 14 1
213 核苷酸補救(R) 14 1
214 鈣調神經磷酸酶依賴性NFAT信號傳導在淋巴球中之作用(N) 52 2
215 由幹細胞因子受體(c-Kit)介導之信號傳導事件(N) 52 2
216 B/2類(腸泌素家族受體) (R) 52 2
217 DNA合成(R) 98 3
218 細胞凋亡之調節(R) 53 2
219 異三聚體G蛋白信號傳導路徑-Gi α及Gs α介導之路徑(P) 147 4
220 麩胱甘肽代謝(K) 54 2
表6.b1
   P值 FDR 節點 基因集中蛋白質之比率
111 0.0936 0.3007 PLCB1,OPRM1,SSTR1,GNG2 0.0097
112 0.0974 0.3007 CHEK2,CCNB2,CDK6 0.0062
113 0.0974 0.3007 PSMD6,CHEK2,PSMB2,CENPP,CCNB2,CLSPN,RFC3 0.022
114 0.0991 0.3007 ATP6V1E2,OLR1,TLR4,CLEC7A,THBS2 0.0138
115 0.0995 0.3007 GLI3,RAPGEF4,ADCY2,PDE4B,SSTR1,CREB5 0.0179
116 0.1005 0.3007 PSMD6,PSMB2,TCF7L2 0.0063
117 0.1008 0.3007 PLCB1,ADCY2,CREB5,GNG2 0.0099
118 0.1017 0.3007 VTI1A,SNAP23 0.003
119 0.1067 0.3007 CBLB,ARHGEF7 0.0031
120 0.1067 0.3007 RICTOR,PDPK1 0.0031
121 0.107 0.3007 OLR1,PDPK1,ACOX2 0.0064
122 0.107 0.3007 CTNNA2,SGCG,TCF7L2 0.0064
123 0.1074 0.3007 COL9A1,RAPGEF1,COL19A1,ELMO1,COL6A1 0.0141
124 0.1137 0.3007 CYP1B1,GSTO2,GSTO1 0.0066
125 0.1137 0.3007 ATP6V1E2,FGFR2,PDPK1 0.0066
126 0.1137 0.3007 PLCB1,ADCY2,CREB5 0.0066
127 0.116 0.3007 PDK1,SUCLG2,LDHAL6B,DLST,PDP1 0.0145
128 0.1169 0.3007 RAPGEF4,PDPK1 0.0033
129 0.1169 0.3007 CLSPN,RFC3 0.0033
130 0.117 0.3007 CHEK2,FZD3,FZD9,ADCY2,PTTG2,CCNB2,WNT2 0.0231
131 0.1189 0.3007 SHH 0.0007
132 0.1189 0.3007 IFNGR1 0.0007
133 0.1189 0.3007 GNG2 0.0007
134 0.1205 0.3007 IL12B,TLR4,LY96 0.0068
135 0.1221 0.3007 ARHGEF7,ELMO1 0.0034
136 0.1221 0.3007 TAB2,AIM2 0.0034
137 0.1221 0.3007 COL9A1,SDC1,COL19A1,ADAM10,COL6A1,LAMA4,LAMA3 0.0233
138 0.1274 0.3007 CBLB,CTNNA2,ELMO1 0.007
139 0.1295 0.3007 PLCB1,ADCY2,GUCY1A2,SNAP23 0.0109
140 0.1326 0.3007 IFNGR1,RAPGEF1 0.0036
141 0.1326 0.3007 SGK1,PDPK1 0.0036
142 0.1328 0.3007 PGM2 0.0008
143 0.1345 0.3007 RIN2,RAPGEF1,PDPK1 0.0072
144 0.135 0.3007 PDPK1,TBC1D1,CCNA1,CREB5 0.0111
145 0.135 0.3007 CPEB4,ADCY2,PTTG2,CCNB2 0.0111
146 0.138 0.3007 ARHGEF7,ADAM10 0.0037
147 0.1417 0.3007 CYP1B1,GSTO2,GSTO1 0.0073
148 0.1417 0.3007 CDK6,TAB2,CCNA1 0.0073
149 0.1417 0.3007 PLCB1,ADCY2,CREB5 0.0073
150 0.142 0.3007 PSMD6,PSMB2,RICTOR,FRK,FGFR2,PDPK1 0.0198
151 0.1434 0.3007 PLCB1,GNG2 0.0038
152 0.1464 0.3007 IL12B 0.0009
153 0.1464 0.3007 SNAP23 0.0009
154 0.1464 0.3007 NRG3 0.0009
155 0.1464 0.3007 PGF 0.0009
156 0.1488 0.3007 PLCB1,GNG2 0.0038
157 0.1488 0.3007 SDC1,LAMA4 0.0038
158 0.1523 0.3007 PLCB1,ADCY2,CREB5,GNG2 0.0116
159 0.1527 0.3007 RAD51B,CLSPN,RFC3 0.0076
160 0.1534 0.3007 PSMD6,PSMB2,CCNB2,HAUS2,CCNA1 0.0159
161 0.1543 0.3007 PSMD6,PSMB2 0.0039
162 0.1565 0.3007 CDK6,LAMA4,LAMA3 0.0077
163 0.1571 0.3007 EXOC2,PAK3,PGF,FGF12,FGFR2,GNG2 0.0205
164 0.1582 0.3007 PSMD6,PSMB2,CDK6,CCNA1 0.0118
165 0.1584 0.3007 GABARAPL1,IKBKE,IFNGR1,CDK6,GNG2 0.0161
166 0.1598 0.3007 SNAP23,SH3D19 0.004
167 0.1598 0.3007 FKBP1A 0.001
168 0.1598 0.3007 DLST 0.001
169 0.1598 0.3007 LAMA3 0.001
170 0.1598 0.3007 ACTR2 0.001
171 0.1603 0.3007 KCNC2,KCNH8,GNG2 0.0078
172 0.1641 0.3007 CBLB,PAK3,NRG3 0.0079
173 0.1641 0.3007 GABARAPL1,ADCY2,GNG2 0.0079
174 0.1641 0.3007 PLCB1,ADCY2,GUCY1A2 0.0079
175 0.1642 0.3007 GABARAPL1,SGK1,CCNB2,PDPK1 0.012
176 0.1653 0.3007 MAP4K3,TAB2 0.0041
177 0.1679 0.3007 CD109,PIGF,OPCML 0.008
178 0.1679 0.3007 PSMD6,PSMB2,PAK3 0.008
179 0.1691 0.3007 ARHGEF7,RHOQ,PAK3,CENPP,SRGAP3,SRGAP2,ACTR2,PDPK1 0.0302
180 0.1702 0.3007 GABARAPL1,PLCB1,ADCY2,GNG2 0.0122
181 0.1709 0.3007 FGFR2,PDPK1 0.0042
182 0.1709 0.3007 GLI3,SHH 0.0042
183 0.1709 0.3007 IL12B,CCL20 0.0042
184 0.1712 0.3007 IL12B,IKBKE,IFNGR1,SRSF3,TAB2 0.0165
185 0.1718 0.3007 PSMD6,GLI3,PSMB2 0.008
186 0.1718 0.3007 COL9A1,CPB2,COL6A1 0.008
187 0.1718 0.3007 ATP6V1E2,TLR4,CCL20 0.008
188 0.1718 0.3007 PLCB1,ADCY2,GUCY1A2 0.008
189 0.173 0.3007 ADAM10 0.0011
190 0.173 0.3007 CDK6 0.0011
191 0.173 0.3007 INHBA 0.0011
192 0.173 0.3007 FYB1 0.0011
193 0.1765 0.3007 UXS1,PGM2 0.0043
194 0.1765 0.3007 RIN2,ADAM10 0.0043
195 0.1795 0.3007 SDC1,GSTO2,GSTO1,SUMO4 0.0124
196 0.1822 0.3007 HBP1,SHH 0.0044
197 0.1835 0.3007 IKBKE,CCL20,TAB2 0.0083
198 0.186 0.3007 GNG2 0.0012
199 0.186 0.3007 CPB2 0.0012
200 0.186 0.3007 ATP6AP2 0.0012
201 0.186 0.3007 GNG2 0.0012
202 0.186 0.3007 INHBA 0.0012
203 0.186 0.3007 GNG2 0.0012
204 0.186 0.3007 IL12B 0.0012
205 0.1878 0.3007 CYP1B1,ADCY2 0.0045
206 0.1878 0.3007 DLG2,NLGN4Y 0.0045
207 0.1914 0.3007 TLR4,LY96,TAB2 0.0085
208 0.1921 0.3007 IKBKE,TLR4,LY96,TAB2 0.0128
209 0.1935 0.3007 FGFR2,PDPK1 0.0046
210 0.1954 0.3007 PLCB1,ADCY2,CPB2 0.0086
211 0.1985 0.3007 ATP6V1E2,NEDD4L,SGK1,UNC80 0.013
212 0.1988 0.3007 ACOX2 0.0013
213 0.1988 0.3007 UCK1 0.0013
214 0.1993 0.3007 AKAP5,FKBP1A 0.0046
215 0.1993 0.3007 SPRED2,PDPK1 0.0046
216 0.1993 0.3007 SHH,WNT2 0.0046
217 0.2034 0.3007 PSMD6,PSMB2,RFC3 0.0088
218 0.205 0.3007 PSMD6,PSMB2 0.0047
219 0.205 0.3007 ADCY2,OPRM1,SSTR1,GNG2 0.0131
220 0.2107 0.3007 GSTO2,GSTO1 0.0048
表6.b2
   基因集 基因集中之數目 在清單中
221 ErbB受體信號傳導網絡(N) 15 1
222 促乳素受體信號傳導(R) 15 1
223 RAB四異戊二烯化(R) 15 1
224 鞘醣脂生物合成-神經節系列(K) 15 1
225 干擾素-γ信號傳導路徑(P) 15 1
226 不匹配修復(R) 15 1
227 PAR4介導之凝血酶信號傳導事件(N) 15 1
228 心肌細胞中之腎上腺素信號傳導(K) 149 4
229 ErbB1下游信號傳導(N) 100 3
230 藉由ROBO受體進行信號傳導(R) 201 5
231 逆行內源性類大麻酚信號傳導(K) 101 3
232 致病性大腸桿菌感染(K) 55 2
233 軍團桿菌病(K) 55 2
234 A/1類(視紅紫質樣受體) (R) 308 7
235 非小細胞肺癌(K) 56 2
236 神經突增生之NCAM信號傳導(R) 56 2
237 Rap1信號傳導(R) 16 1
238 LPA4介導之信號傳導事件(N) 16 1
239 肌蛋白長絲之y分支鏈(B) 16 1
240 akt信號傳導路徑(B) 16 1
241 pi3k亞單位p85在調節肌蛋白組織及細胞遷移中之作用(B) 16 1
242 HIF-1信號傳導路徑(K) 103 3
243 急性骨髓白血病(K) 57 2
244 細胞老化(K) 154 4
245 T細胞受體信號傳導路徑(K) 105 3
246 多配體蛋白聚糖-1介導之信號傳導事件(N) 17 1
247 經由蛋白酶活化受體(PAR)進行凝血酶信號傳導(R) 17 1
248 朊病毒路徑(B) 17 1
249 β5 β6 β7及β8整合素細胞表面相互作用(N) 17 1
250 初級膽酸生物合成(K) 17 1
251 信號擴增(R) 17 1
252 葡糖胺聚糖代謝(R) 106 3
253 血小板內穩定(R) 59 2
254 離胺酸分解(K) 59 2
255 化合物之II期共軛(R) 59 2
256 細胞介素-細胞介素受體相互作用(K) 265 6
257 長期抑鬱(K) 60 2
258 G α (12/13)信號傳導事件(R) 60 2
259 內部核糖體入口路徑(B) 18 1
260 抗胰島素症(K) 109 3
261 介白素-4及介白素-13信號傳導(R) 110 3
262 TNF信號傳導路徑(K) 110 3
263 內皮素(N) 62 2
264 大腸直腸癌(K) 62 2
265 細胞週期蛋白及細胞週期調節(B) 19 1
266 LPA受體介導之事件(N) 63 2
267 Ras路徑(P) 63 2
268 IL4介導之信號傳導事件(N) 64 2
269 胞質DNA感測路徑(K) 64 2
270 麩胺酸能突觸(K) 114 3
271 胰島素處理(R) 20 1
272 一個葉酸碳池(K) 20 1
273 突觸黏附樣分子(R) 20 1
274 腎素分泌物(K) 65 2
275 BCR信號傳導路徑(N) 65 2
276 cGMP-PKG信號傳導路徑(K) 168 4
277 血管新生(P) 66 2
278 細胞週期：g1/s檢查點(B) 21 1
279 生長激素信號傳導路徑(B) 21 1
280 PDGFR-α信號傳導路徑(N) 21 1
281 Notch信號傳導路徑(P) 21 1
282 細胞凋亡中之凋亡蛋白酶級聯(B) 21 1
283 癌症中之中央碳代謝(K) 67 2
284 naïve CD4+ T細胞中之TCR信號傳導(N) 67 2
285 腎細胞癌(K) 67 2
286 多元胺之代謝(R) 67 2
287 糖酵解/葡糖新生(K) 67 2
288 幽門螺旋桿菌感染中之上皮細胞信號傳導(K) 68 2
289 乙醛酸鹽代謝及甘胺酸分解(R) 22 1
290 腸促胰島素合成、分泌及失活(R) 22 1
291 去泛素化(R) 229 5
292 血管平滑肌收縮(K) 121 3
293 A型流感(K) 175 4
294 嘌呤代謝(K) 175 4
295 CDC42信號傳導事件(N) 70 2
296 RIG-I樣受體信號傳導路徑(K) 70 2
297 細胞接合組織(R) 70 2
298 藥物代謝-細胞色素P450 (K) 70 2
299 藉由B細胞受體(BCR)進行信號傳導(R) 176 4
300 亨丁頓病(P) 122 3
301 由Hedgehog家族介導之信號傳導事件(N) 23 1
302 腎素-血管緊張素系統(K) 23 1
303 eif-4e及p70s6激酶之調節(B) 23 1
304 黑素瘤(K) 71 2
305 結核病(K) 179 4
306 黏附接合點(K) 72 2
307 mtor信號傳導路徑(B) 24 1
308 肌生成(R) 24 1
309 生長激素受體信號傳導(R) 24 1
310 維生素消化及吸收(K) 24 1
311 組胺酸代謝(K) 24 1
312 藉由TGF-β受體複合物進行信號傳導(R) 73 2
313 干擾素γ信號傳導(R) 73 2
314 慢性骨髓白血病(K) 73 2
315 藉由氧調節低氧誘導因子(HIF) (R) 73 2
316 RAB GEF將GTP交換成RAB上之GDP(R) 73 2
317 糖基化磷脂醯肌醇(GPI)-錨定生物合成(K) 25 1
318 其他介白素信號傳導(R) 25 1
319 非基因雄激素信號傳導(N) 25 1
320 nk細胞介導之細胞毒性中之ras非依賴性路徑(B) 25 1
321 膽酸及膽汁鹽代謝(R) 25 1
322 C-MYC路徑(N) 25 1
323 DNA複製之調節(R) 74 2
324 水溶性維生素及輔因子之代謝(R) 74 2
325 RNA聚合酶II轉錄(R) 826 15
326 胃酸分泌物(K) 75 2
327 p73轉錄因子網絡(N) 75 2
328 WNT配體生物合成及遷移(R) 26 1
329 抗利尿素經由水孔蛋白調節腎水內穩定(R) 26 1
330 PI3激酶路徑(P) 26 1
表6.c1
   P值 FDR 節點 基因集中蛋白質之比率
221 0.2114 0.3007 NRG3 0.0013
222 0.2114 0.3007 GHR 0.0013
223 0.2114 0.3007 RAB38 0.0013
224 0.2114 0.3007 ST6GALNAC3 0.0013
225 0.2114 0.3007 IFNGR1 0.0013
226 0.2114 0.3007 MSH2 0.0013
227 0.2114 0.3007 GNG2 0.0013
228 0.2115 0.3007 PLCB1,RAPGEF4,ADCY2,CREB5 0.0133
229 0.2116 0.3007 RICTOR,ACTR2,PDPK1 0.0089
230 0.2145 0.3007 PSMD6,AKAP5,PSMB2,SRGAP3,SRGAP2 0.018
231 0.2157 0.3007 PLCB1,ADCY2,GNG2 0.009
232 0.2165 0.3007 TLR4,LY96 0.0049
233 0.2165 0.3007 IL12B,TLR4 0.0049
234 0.2173 0.3007 GPR183,GPR18,OXGR1,CCL20,OPRM1,SSTR1,CX3CR1 0.0275
235 0.2223 0.3007 CDK6,PDPK1 0.005
236 0.2223 0.3007 COL9A1,COL6A1 0.005
237 0.2238 0.3007 RAPGEF4 0.0014
238 0.2238 0.3007 ADCY2 0.0014
239 0.2238 0.3007 ACTR2 0.0014
240 0.2238 0.3007 GHR 0.0014
241 0.2238 0.3007 ACTR2 0.0014
242 0.2239 0.3007 PDK1,IFNGR1,TLR4 0.0092
243 0.2281 0.3007 CCNA1,TCF7L2 0.0051
244 0.2281 0.3007 CHEK2,CCNB2,CDK6,CCNA1 0.0138
245 0.2322 0.3007 CBLB,PAK3,PDPK1 0.0094
246 0.236 0.3007 SDC1 0.0015
247 0.236 0.3007 GNG2 0.0015
248 0.236 0.3007 LAMA3 0.0015
249 0.236 0.3007 SDC1 0.0015
250 0.236 0.3007 ACOX2 0.0015
251 0.236 0.3007 GNG2 0.0015
252 0.2363 0.3007 OMD,SDC1,OGN 0.0095
253 0.2397 0.3007 GUCY1A2,GNG2 0.0053
254 0.2397 0.3007 DLST,PRDM2 0.0053
255 0.2397 0.3007 GSTO2,GSTO1 0.0053
256 0.2441 0.3007 IL12B,IFNGR1,CCL20,INHBA,GHR,CX3CR1 0.0237
257 0.2456 0.3007 PLCB1,GUCY1A2 0.0054
258 0.2456 0.3007 ARHGEF7,GNG2 0.0054
259 0.248 0.3007 CASP4 0.0016
260 0.2489 0.3007 PPP1R3D,PDPK1,CREB5 0.0097
261 0.2531 0.3007 IL12B,OPRM1,IRF4 0.0098
262 0.2531 0.3007 CCL20,TAB2,CREB5 0.0098
263 0.2572 0.3007 PLCB1,ADCY2 0.0055
264 0.2572 0.3007 MSH2,TCF7L2 0.0055
265 0.2598 0.3007 CCNA1 0.0017
266 0.2631 0.3007 ADCY2,GNG2 0.0056
267 0.2631 0.3007 PAK3,PDPK1 0.0056
268 0.2689 0.3007 OPRM1,IRF4 0.0057
269 0.2689 0.3007 IKBKE,AIM2 0.0057
270 0.2701 0.3007 PLCB1,ADCY2,GNG2 0.0102
271 0.2715 0.3007 EXOC2 0.0018
272 0.2715 0.3007 MTHFD1 0.0018
273 0.2715 0.3007 LRFN2 0.0018
274 0.2747 0.3007 PLCB1,GUCY1A2 0.0058
275 0.2747 0.3007 IBTK,PDPK1 0.0058
276 0.2761 0.3007 PLCB1,ADCY2,GUCY1A2,CREB5 0.015
277 0.2806 0.3007 FZD3,TCF7L2 0.0059
278 0.2829 0.3007 CCNA1 0.0019
279 0.2829 0.3007 GHR 0.0019
280 0.2829 0.3007 RAPGEF1 0.0019
281 0.2829 0.3007 ADAM10 0.0019
282 0.2829 0.3007 CASP4 0.0019
283 0.2864 0.3007 PDK1,FGFR2 0.006
284 0.2864 0.3007 FYB1,PDPK1 0.006
285 0.2864 0.3007 RAPGEF1,PAK3 0.006
286 0.2864 0.3007 PSMD6,PSMB2 0.006
287 0.2864 0.3007 LDHAL6B,PGM2 0.006
288 0.2922 0.3007 ATP6V1E2,ADAM10 0.0061
289 0.2942 0.3007 DLST 0.002
290 0.2942 0.3007 TCF7L2 0.002
291 0.2972 0.3007 PSMD6,PSMB2,INO80C,CLSPN,CCNA1 0.0205
292 0.3001 0.3007 PLCB1,ADCY2,GUCY1A2 0.0108
293 0.3007 0.3007 IL12B,IKBKE,IFNGR1,TLR4 0.0156
294 0.3007 0.3007 ADCY2,GUCY1A2,PDE4B,PGM2 0.0156
295 0.3039 0.3039 ARHGEF7,ACTR2 0.0063
296 0.3039 0.3039 IL12B,IKBKE 0.0063
297 0.3039 0.3039 CDH17,LAMA3 0.0063
298 0.3039 0.3039 GSTO2,GSTO1 0.0063
299 0.3043 0.3043 CBLB,PSMD6,PSMB2,FKBP1A 0.0157
300 0.3044 0.3044 RHOQ,CAPN6,ACTR2 0.0109
301 0.3053 0.3053 SHH 0.0021
302 0.3053 0.3053 ATP6AP2 0.0021
303 0.3053 0.3053 GHR 0.0021
304 0.3097 0.3097 CDK6,FGF12 0.0063
305 0.3149 0.3149 IL12B,IFNGR1,TLR4,CLEC7A 0.016
306 0.3155 0.3155 CTNNA2,TCF7L2 0.0064
307 0.3162 0.3162 GHR 0.0021
308 0.3162 0.3162 CTNNA2 0.0021
309 0.3162 0.3162 GHR 0.0021
310 0.3162 0.3162 SLC19A3 0.0021
311 0.3162 0.3162 HNMT 0.0021
312 0.3212 0.3212 NEDD4L,FKBP1A 0.0065
313 0.3212 0.3212 IFNGR1,IRF4 0.0065
314 0.3212 0.3212 CBLB,CDK6 0.0065
315 0.3212 0.3212 PSMD6,PSMB2 0.0065
316 0.3212 0.3212 RIN2,RAB38 0.0065
317 0.327 0.327 PIGF 0.0022
318 0.327 0.327 SDC1 0.0022
319 0.327 0.327 GNG2 0.0022
320 0.327 0.327 KLRD1 0.0022
321 0.327 0.327 ACOX2 0.0022
322 0.327 0.327 HBP1 0.0022
323 0.327 0.327 PSMD6,PSMB2 0.0066
324 0.327 0.327 MTHFD1,GSTO2 0.0066
325 0.3281 0.3281 PSMD6,CHEK2,NEDD4L,INTS6,GLI3,SGK1,PSMB2,RICTOR,KCTD6,MSH2,SRSF3,CDK6,RFC3,PDPK1,TCF7L2 0.0738
326 0.3328 0.3328 PLCB1,ADCY2 0.0067
327 0.3328 0.3328 NEDD4L,CDK6 0.0067
328 0.3376 0.3376 WNT2 0.0023
329 0.3376 0.3376 ADCY2 0.0023
330 0.3376 0.3376 PDPK1 0.0023
表6.c2
   基因集 基因集中之數目 在清單中
331 IL27介導之信號傳導事件(N) 26 1
332 甘油磷脂生物合成(R) 76 2
333 多巴胺激導性突觸(K) 130 3
334 p38 MAPK信號傳導路徑(N) 27 1
335 胰島素介導之葡萄糖轉運(N) 27 1
336 肝糖代謝(R) 27 1
337 收集管道酸分泌物(K) 27 1
338 DDX58/IFIH1介導之干擾素-α/β之誘導(R) 79 2
339 核β連環蛋白信號傳導及靶基因轉錄之調節(N) 79 2
340 S期(R) 134 3
341 異三聚體G蛋白信號傳導路徑-桿狀外片段光轉導(P) 28 1
342 顫蛋白信號傳導路徑(N) 28 1
343 由STAT5介導之IL2信號傳導事件(N) 28 1
344 背-腹軸形成(K) 28 1
345 ErbB4信號傳導事件(N) 28 1
346 藉由NOTCH2進行信號傳導(R) 29 1
347 核小體組裝(R) 29 1
348 甲狀腺癌(K) 29 1
349 Hippo信號傳導路徑-多物種(K) 29 1
350 CD40/CD40L信號傳導(N) 29 1
351 緊密接合點(K) 137 3
352 介白素-1家族信號傳導(R) 137 3
353 MAPK信號傳導路徑(K) 255 5
354 有絲分裂細胞週期之調節(R) 83 2
355 磷酸戊糖路徑(K) 30 1
356 CDC42活性之調節(N) 30 1
357 IGF1路徑(N) 30 1
358 黏附分子黏附路徑(N) 30 1
359 α-突觸核蛋白信號傳導(N) 30 1
360 無鹼基位點(AP位點)之解析(R) 31 1
361 p38-α及p38-β之調節(N) 31 1
362 Aurora A信號傳導(N) 31 1
363 半乳糖代謝(K) 31 1
364 黏蛋白型O-聚糖生物合成(K) 31 1
365 三葉因子引發黏膜癒合(B) 31 1
366 M/G1轉變(R) 85 2
367 沙門氏菌感染(K) 86 2
368 多配體蛋白聚糖-4介導之信號傳導事件(N) 32 1
369 吞噬細胞中之ROS、RNS生產(R) 32 1
370 FAS (CD95)信號傳導路徑(N) 32 1
371 軸突引導因子介導之信號傳導事件(N) 32 1
372 DAG及IP3信號傳導(R) 32 1
373 鐸樣受體路徑(B) 32 1
374 多配體蛋白聚糖-2介導之信號傳導事件(N) 32 1
375 非典型Wnt信號傳導路徑(N) 32 1
376 磷脂酶D信號傳導路徑(K) 144 3
377 藉由結合富含AU之元素的蛋白質調節mRNA(R) 87 2
378 病毒癌發生(K) 203 4
379 埃-巴二氏病毒感染(K) 204 4
380 α4 β1整合素信號傳導事件(N) 33 1
381 致癌基因誘導之老化(R) 33 1
382 氧化氮在心臟中之作用(B) 33 1
383 EPO信號傳導路徑(N) 33 1
384 高爾基體內及逆行高爾基體-至-ER運輸(R) 147 3
385 ABC家族蛋白質介導之轉運(R) 89 2
386 Arf6遷移事件(N) 34 1
387 IL1介導之信號傳導事件(N) 34 1
388 ATM路徑(N) 34 1
389 擴張型心肌症(K) 90 2
390 血管壁處之細胞表面相互作用(R) 208 4
391 Fc ε受體(FCERI)信號傳導(R) 209 4
392 Arf6信號傳導事件(N) 35 1
393 由p38-α及p38-β介導之信號傳導(N) 35 1
394 FGF信號傳導路徑(P) 92 2
395 Th1及Th2細胞分化(K) 92 2
396 GnRH信號傳導路徑(K) 92 2
397 由PI3K及PLC-γ介導之Trk受體信號傳導(N) 36 1
398 DNA複製(K) 36 1
399 澱粉及蔗糖代謝(K) 36 1
400 藉由akt使gsk3失活造成b-連環蛋白在肺泡巨噬細胞中之聚集(B) 36 1
401 減數分裂結合(R) 36 1
402 藉由視黃酸進行信號傳導(R) 36 1
403 初生黏附接合中之E-鈣黏素信號傳導(N) 36 1
404 壽命調節路徑(K) 94 2
405 肌蛋白細胞骨架之調節(K) 214 4
406 AP1家庭成員Fra1及Fra2之驗證轉錄目標(N) 37 1
407 IL23介導之信號傳導事件(N) 37 1
408 二十碳四烯酸代謝(R) 37 1
409 TNF信號傳導(R) 38 1
410 類視黃素代謝及轉運(R) 38 1
411 同種異體移植排斥反應(K) 38 1
412 介白素-3、介白素-5及GM-CSF信號傳導(R) 38 1
413 膽汁鹽及有機酸、金屬離子及胺化合物之轉運(R) 38 1
414 由II類HDAC介導之信號傳導事件(N) 38 1
415 肌醇磷酸鹽代謝(R) 38 1
416 端粒維持(R) 38 1
417 Jak-STAT信號傳導路徑(K) 158 3
418 丙酮酸酯代謝(K) 39 1
419 催產素信號傳導路徑(K) 159 3
420 磷脂醯環己六醇信號傳導系統(K) 99 2
421 TRP通道之發炎性介體調節(K) 99 2
422 回應於WNT之TCF依賴性信號傳導(R) 160 3
423 色胺酸代謝(K) 40 1
424 神經傳遞素釋放週期(R) 40 1
425 自噬(K) 40 1
426 TNFR2非典型NF-kB路徑(R) 101 2
427 癌症中之膽鹼代謝(K) 101 2
428 BMP受體信號傳導(N) 41 1
429 移植物抗宿主病(K) 41 1
430 同源重組(K) 41 1
431 核苷酸切除修復(R) 102 2
432 離子通道及其在血管內皮中之功能作用(B) 42 1
433 卟啉及葉綠素代謝(K) 42 1
434 I型糖尿病(K) 43 1
435 藉由ERBB4進行信號傳導(R) 43 1
436 藉由NOTCH3進行信號傳導(R) 43 1
437 LKB1信號傳導事件(N) 43 1
表6.d1
   P值 FDR 節點 基因集中蛋白質之比率
331 0.3376 0.3376 IL12B 0.0023
332 0.3385 0.3385 CDS1,SLC44A1 0.0068
333 0.3388 0.3388 PLCB1,CREB5,GNG2 0.0116
334 0.348 0.348 TAB2 0.0024
335 0.348 0.348 RHOQ 0.0024
336 0.348 0.348 PGM2 0.0024
337 0.348 0.348 ATP6V1E2 0.0024
338 0.3557 0.3557 HERC5,IKBKE 0.0071
339 0.3557 0.3557 HBP1,TCF7L2 0.0071
340 0.356 0.356 PSMD6,PSMB2,RFC3 0.012
341 0.3583 0.3583 GNG2 0.0025
342 0.3583 0.3583 RAPGEF1 0.0025
343 0.3583 0.3583 CDK6 0.0025
344 0.3583 0.3583 CPEB4 0.0025
345 0.3583 0.3583 TAB2 0.0025
346 0.3684 0.3684 ADAM10 0.0026
347 0.3684 0.3684 CENPP 0.0026
348 0.3684 0.3684 TCF7L2 0.0026
349 0.3684 0.3684 FAT4 0.0026
350 0.3684 0.3684 CBLB 0.0026
351 0.3689 0.3689 CTNNA2,MAGI1,VAPA 0.0122
352 0.3689 0.3689 PSMD6,PSMB2,TAB2 0.0122
353 0.378 0.378 PPP5D1,MAP4K3,TAB2,FGF12,FGFR2 0.0228
354 0.3783 0.3783 PSMD6,PSMB2 0.0074
355 0.3783 0.3783 PGM2 0.0027
356 0.3783 0.3783 ARHGEF7 0.0027
357 0.3783 0.3783 PDPK1 0.0027
358 0.3783 0.3783 RAPGEF1 0.0027
359 0.3783 0.3783 FKBP1A 0.0027
360 0.3881 0.3881 RFC3 0.0028
361 0.3881 0.3881 PAK3 0.0028
362 0.3881 0.3881 ARHGEF7 0.0028
363 0.3881 0.3881 PGM2 0.0028
364 0.3881 0.3881 GALNT1 0.0028
365 0.3881 0.3881 GHR 0.0028
366 0.3894 0.3894 PSMD6,PSMB2 0.0076
367 0.395 0.395 IFNGR1,TLR4 0.0077
368 0.3977 0.3977 LAMA3 0.0029
369 0.3977 0.3977 ATP6V1E2 0.0029
370 0.3977 0.3977 PDPK1 0.0029
371 0.3977 0.3977 ELMO1 0.0029
372 0.3977 0.3977 ADCY2 0.0029
373 0.3977 0.3977 LY96 0.0029
374 0.3977 0.3977 LAMA3 0.0029
375 0.3977 0.3977 TAB2 0.0029
376 0.3987 0.3987 PLCB1,RAPGEF4,ADCY2 0.0129
377 0.4005 0.4005 PSMD6,PSMB2 0.0078
378 0.4005 0.4005 EGR3,CDK6,CCNA1,CREB5 0.0181
379 0.4041 0.4041 PSMD6,CD58,TAB2,CCNA1 0.0182
380 0.4072 0.4072 THBS2 0.0029
381 0.4072 0.4072 CDK6 0.0029
382 0.4072 0.4072 GUCY1A2 0.0029
383 0.4072 0.4072 RAPGEF1 0.0029
384 0.4114 0.4114 COG5,VTI1A,GALNT1 0.0131
385 0.4115 0.4115 PSMD6,PSMB2 0.008
386 0.4165 0.4165 EXOC2 0.003
387 0.4165 0.4165 TAB2 0.003
388 0.4165 0.4165 CHEK2 0.003
389 0.417 0.417 ADCY2,SGCG 0.008
390 0.4183 0.4183 SDC1,OLR1,EPCAM,CD58 0.0186
391 0.4218 0.4218 PSMD6,PSMB2,TAB2,PDPK1 0.0187
392 0.4257 0.4257 IPCEF1 0.0031
393 0.4257 0.4257 HBP1 0.0031
394 0.4279 0.4279 FGF12,FGFR2 0.0082
395 0.4279 0.4279 IL12B,IFNGR1 0.0082
396 0.4279 0.4279 PLCB1,ADCY2 0.0082
397 0.4348 0.4348 PDPK1 0.0032
398 0.4348 0.4348 RFC3 0.0032
399 0.4348 0.4348 PGM2 0.0032
400 0.4348 0.4348 LY96 0.0032
401 0.4348 0.4348 SYCP2 0.0032
402 0.4348 0.4348 PDK1 0.0032
403 0.4348 0.4348 RAPGEF1 0.0032
404 0.4386 0.4386 ADCY2,CREB5 0.0084
405 0.4394 0.4394 ARHGEF7,PAK3,FGF12,FGFR2 0.0191
406 0.4437 0.4437 LAMA3 0.0033
407 0.4437 0.4437 IL12B 0.0033
408 0.4437 0.4437 CYP1B1 0.0033
409 0.4524 0.4524 TAB2 0.0034
410 0.4524 0.4524 SDC1 0.0034
411 0.4524 0.4524 IL12B 0.0034
412 0.4524 0.4524 RAPGEF1 0.0034
413 0.4524 0.4524 SLC44A1 0.0034
414 0.4524 0.4524 GNG2 0.0034
415 0.4524 0.4524 PLCB1 0.0034
416 0.4524 0.4524 RFC3 0.0034
417 0.4571 0.4571 IL12B,IFNGR1,GHR 0.0141
418 0.4611 0.4611 LDHAL6B 0.0035
419 0.4611 0.4611 PLCB1,ADCY2,GUCY1A2 0.0142
420 0.465 0.465 CDS1,PLCB1 0.0088
421 0.465 0.465 PLCB1,ADCY2 0.0088
422 0.4652 0.4652 PSMD6,PSMB2,TCF7L2 0.0143
423 0.4695 0.4695 CYP1B1 0.0036
424 0.4695 0.4695 ARL6IP5 0.0036
425 0.4695 0.4695 GABARAPL1 0.0036
426 0.4753 0.4753 PSMD6,PSMB2 0.009
427 0.4753 0.4753 SLC44A1,PDPK1 0.009
428 0.4779 0.4779 TAB2 0.0037
429 0.4779 0.4779 KLRD1 0.0037
430 0.4779 0.4779 RAD51B 0.0037
431 0.4804 0.4804 INO80C,RFC3 0.0091
432 0.4861 0.4861 GUCY1A2 0.0038
433 0.4861 0.4861 MMAB 0.0038
434 0.4942 0.4942 IL12B 0.0038
435 0.4942 0.4942 TAB2 0.0038
436 0.4942 0.4942 ADAM10 0.0038
437 0.4942 0.4942 MAP2 0.0038
表6.d2
   基因集 基因集中之數目 來自清單 P值
1 nk細胞介導之細胞毒性中之ras非依賴性路徑(B) 25 5 0.0000286
2 Jak-STAT信號傳導路徑(K) 158 10 0.0000766
3 自然殺傷細胞介導之細胞毒性(K) 135 9 0.000120
4 經醛固酮調節的鈉再吸收(K) 39 5 0.000226
5 DAP12相互作用(R) 44 5 0.000391
6 催產素信號傳導路徑(K) 159 9 0.000395
7 由肝細胞生長因子受體(c-Mct)介導之信號傳導事件(N) 80 6 0.000912
8 細胞介素-細胞介素受體相互作用(K) 265 11 0.00119
9 mTOR信號傳導路徑(K) 154 8 0.00143
10 由p38-α及p38-β介導之信號傳導(N) 35 4 0.00149
11 MAPK信號傳導路徑(K) 255 10 0.00298
12 代謝型麩胺酸受體第III族路徑(P) 6 2 0.00321
13 癌症中之路徑(K) 397 13 0.00353
14 調節幹細胞之多能性的信號傳導路徑(K) 142 7 0.00374
15 介白素-6家族信號傳導(R) 23 3 0.00412
16 離子通道轉運(R) 145 7 0.00418
17 突觸前去極化及鈣通道開放(R) 7 2 0.00433
18 抗原處理及代表(K) 77 5 0.00448
19 卵巢類固醇生成(K) 50 4 0.00529
20 CD4+ TCR路徑中之鈣信號傳導(N) 27 3 0.00640
21 小細胞肺癌(K) 86 5 0.00706
22 沙門氏菌感染(K) 86 5 0.00706
23 顫蛋白信號傳導路徑(N) 28 3 0.00707
24 亨丁頓病(P) 122 6 0.00719
25 骨橋蛋白介導之事件(N) 29 3 0.00777
26 脂肪細胞中脂肪分解之調節(K) 56 4 0.00781
27 由局部黏著斑激酶介導之信號傳導事件(N) 60 4 0.00987
28 藉由VEGF進行信號傳導(R) 94 5 0.0101
29 VEGF信號傳導路徑(K) 61 4 0.0104
30 IL4介導之信號傳導事件(N) 64 4 0.0123
31 mTOR信號傳導路徑(N) 64 4 0.0123
32 卡波西氏肉瘤相關疱疹病毒感染(K) 180 7 0.0128
33 BCR信號傳導路徑(N) 65 4 0.0129
34 ErbB1下游信號傳導(N) 100 5 0.0129
35 流體剪應力及動脈粥樣硬化(K) 139 6 0.013
36 鈣信號傳導路徑(K) 182 7 0.0135
37 血管新生(P) 66 4 0.0136
38 初生黏附接合中之E-鈣黏素信號傳導(N) 36 3 0.0139
39 二十碳四烯酸代謝(R) 37 3 0.0149
40 T細胞受體信號傳導路徑(K) 105 5 0.0156
41 鐸樣受體信號傳導路徑(K) 106 5 0.0162
42  CD4+ TCR路徑中之JNK信號傳導(N) 14 2 0.0163
43 Th17細胞分化(K) 107 5 0.0168
44 IFN-γ路徑(N) 40 3 0.0183
45 氧化應力應答(P) 40 3 0.0183
46 介白素-4及介白素-13信號傳導(R) 110 5 0.0187
47 TNF信號傳導路徑(K) 110 5 0.0187
48 B細胞受體信號傳導路徑(K) 73 4 0.0189
49 神經生長因子路徑(ngf) (B) 16 2 0.0209
50 硫胺代謝(K) 16 2 0.0209
51 麩胺酸能突觸(K) 114 5 0.0214
52 cAMP信號傳導路徑(K) 200 7 0.0214
53 局部黏附(K) 201 7 0.022
54 藉由hdac及鈣/調鈣蛋白依賴性激酶(camk)控制骨骼肌生成(B) 17 2 0.0234
55 整合素相關激酶信號傳導(N) 45 3 0.0248
56 胰島素路徑(N) 45 3 0.0248
57 PDGFR-β信號傳導路徑(N) 120 5 0.0259
58 EPHA2正向信號傳導(N) 18 2 0.026
59 T細胞活化(P) 81 4 0.0263
60 IL6介導之信號傳導事件(N) 47 3 0.0277
61 血管新生中之整合素(N) 47 3 0.0277
62 TGF-β受體信號傳導(N) 47 3 0.0277
63 5HT1型受體介導之信號傳導路徑(P) 19 2 0.0287
64 黏附接合穩定性及解組裝之轉譯後調節(N) 48 3 0.0292
65 II型糖尿病(K) 48 3 0.0292
66 GPVI介導之活化級聯(R) 49 3 0.0308
67 突觸黏附樣分子(R) 20 2 0.0315
68 有絲分裂中期及分裂後期(R) 171 6 0.0318
69 藉由PDGF進行信號傳導(R) 51 3 0.034
70 SHP2信號傳導(N) 51 3 0.034
71 角質細胞中之E-鈣黏蛋白信號傳導(N) 21 2 0.0344
72 igf-1信號傳導路徑(B) 21 2 0.0344
73 PDGFR-α信號傳導路徑(N) 21 2 0.0344
74 鬆弛素信號傳導路徑(K) 130 5 0.0347
75 有絲分裂前中期(R) 175 6 0.035
76 藉由格列維克(gleevec)抑制細胞增殖(B) 22 2 0.0374
77 map激酶信號傳導路徑(B) 53 3 0.0375
78 Th1及Th2細胞分化(K) 92 4 0.0391
79 能量代謝之整合(R) 92 4 0.0391
80 RAC1信號傳導路徑(N) 54 3 0.0392
81 GABA-B_受體_II_信號傳導(P) 3 1 0.0405
82 5HT4型受體介導之信號傳導路徑(P) 23 2 0.0405
83 由Hedgehog家族介導之信號傳導事件(N) 23 2 0.0405
84 erk5在神經元存活路徑中之作用(B) 23 2 0.0405
85 介白素信號傳導路徑(P) 55 3 0.041
86 內皮素信號傳導路徑(P) 55 3 0.041
87 基底細胞癌(K) 55 3 0.041
88 皮質類固醇及心臟保護(B) 24 2 0.0438
89 mtor信號傳導路徑(B) 24 2 0.0438
90 肌生成(R) 24 2 0.0438
91 藉由ρ GTP酶進行信號傳導(R) 338 9 0.0451
92 趨化細胞素信號傳導路徑(K) 187 6 0.0457
93 C-MYC路徑(N) 25 2 0.0471
94 肥大細胞中之fc ε受體i信號傳導(B) 25 2 0.0471
95 tpo信號傳導路徑(B) 25 2 0.0471
96 Wnt信號傳導路徑(K) 143 5 0.0487
97 神經傳遞素受體及突觸後信號傳送(R) 143 5 0.0487
98 TRP通道之發炎性介體調節(K) 99 4 0.0488
99 雌激素信號傳導路徑(K) 100 4 0.0503
100 S1P2路徑(N) 26 2 0.0505
101 年輕起病成人型糖尿病(K) 26 2 0.0505
102 pdgf信號傳導路徑(B) 26 2 0.0505
103 神經營養因子介導之Trk受體信號傳導(N) 60 3 0.0508
104 黑素生成(K) 101 4 0.0518
105 糖尿病併發症中之AGE-RAGE信號傳導路徑(K) 101 4 0.0518
表7.a1
   FDR 節點 基因集中蛋白質之比率
1 0.0186 PIK3R1,KLRC1,KLRC2,KLRC3,KLRD1 0.0022
2 0.025 PIK3R1,IFNGR1,OSMR,CRLF2,IL13RA1,IL4R,LIFR,IL6ST,CSF2RA,PTPN2 0.0141
3 0.0259 PIK3R1,KLRK1,PPP3CC,VAV3,IFNGR1,KLRC1,KLRC2,KLRC3,KLRD1 0.0121
4 0.0369 NEDD4L,PIK3R1,SGK1,SCNN1G,SCNN1B 0.0035
5 0.0426 PIK3R1,KLRK1,VAV3,KLRC2,KLRD1 0.0039
6 0.0426 MEF2C,PIK3R1,JUN,RYR3,PPP3CC,ADCY2,PTGS2,PLA2G4A,CACNG2 0.0142
7 0.0848 RIN2,PIK3R1,JUN,CTNNB1,DEPTOR,PTPN2 0.0072
8 0.0967 IFNGR1,OSMR,CRLF2,CCL4L1,IL13RA1,IL4R,LIFR,IL6ST,CCL3L3,CSF2RA,TNFRSF17 0.0237
9 0.0967 ATP6V1G1,SEH1L,PIK3R1,FZD3,FZD9,SGK1,RICTOR,DEPTOR 0.0138
10 0.0967 MEF2C,JUN,PTGS2,PLA2G4A 0.0031
11 0.1613 MEF2C,JUN,GADD45G,PPP3CC,MECOM,MAP4K3,MAP3K8,CACNA1E,PLA2G4A,CACNG2 0.0228
12 0.1613 GRIN2A,SNAP29 0.0005
13 0.1613 PIK3R1,FZD3,JUN,FZD9,MECOM,ADCY2,PTGS2,ARNT2,CTNNB1,COL4A2,COL4A1,CSF2RA,TRAF5 0.0355
14 0.1613 PIK3R1,FZD3,FZD9,CTNNB1,LIFR,IL6ST,MEIS1 0.0127
15 0.1613 OSMR,LIFR,IL6ST 0.0021
16 0.1613 ATP6V1G1,NEDD4L,RYR3,SGK1,SCNN1G,SCNN1B,TRPV4 0.013
17 0.1613 CACNA1E,CACNG2 0.0006
18 0.1613 KLRC1,KLRC2,KLRC3,KLRC4,KLRD1 0.0069
19 0.1798 CYP1B1,ADCY2,PTGS2,PLA2G4A 0.0045
20 0.1941 JUN,AKAP5,PTGS2 0.0024
21 0.1941 PIK3R1,PTGS2,COL4A2,COL4A1,TRAF5 0.0077
22 0.1941 JUN,IFNGR1,DYNC1I1,CCL4L1,CCL3L3 0.0077
23 0.1941 PIK3R1,GRIN2A,DAB1 0.0025
24 0.1941 CYFIP2,GRIN2A,JUN,GRIK1,DYNC1I1,CAPN2 0.0109
25 0.1953 PIK3R1,JUN,VAV3 0.0026
26 0.1953 PIK3R1,ADCY2,PTGS2,ADRB2 0.005
27 0.2296 PIK3R1,JUN,CAPN2,ELMO1 0.0054
28 0.2296 CYFIP2,PIK3R1,VAV3,RICTOR,ELMO1 0.0084
29 0.2296 PIK3R1,PPP3CC,PTGS2,PLA2G4A 0.0055
30 0.2308 PIK3R1,IL13RA1,IL4R,OPRM1 0.0057
31 0.2308 SGK1,RICTOR,DEPTOR,PDCD4 0.0057
32 0.2308 PIK3R1,JUN,PPP3CC,IFNGR1,PTGS2,CTNNB1,IL6ST 0.0161
33 0.2308 PIK3R1,JUN,PPP3CC,IBTK 0.0058
34 0.2308 CYFIP2,MEF2C,JUN,RICTOR,CAPN2 0.0089
35 0.2308 MEF2C,MGST1,PIK3R1,JUN,CTNNB1,TRPV4 0.0124
36 0.2308 GRIN2A,RYR3,PPP3CC,ADCY2,CHRM5,ADRB2,CACNA1E 0.0163
37 0.2308 FZD3,JUN,GRB14,PLA2G4A 0.0059
38 0.2358 CYFIP2,PIK3R1,CTNNB1 0.0032
39 0.2386 CYP1B1,PTGS2,PLA2G4A 0.0033
40 0.2427 PIK3R1,JUN,PPP3CC,VAV3,MAP3K8 0.0094
41 0.2427 PIK3R1,JUN,CCL4L1,MAP3K8,CCL3L3 0.0095
42 0.2427 JUN,MAP3K8 0.0013
43 0.2427 JUN,PPP3CC,IFNGR1,IL4R,IL6ST 0.0096
44 0.2427 PIK3R1,IFNGR1,PTPN2 0.0036
45 0.2427 MEF2C,JUN,PLA2G4A 0.0036
46 0.2427 PIK3R1,PTGS2,IL13RA1,IL4R,OPRM1 0.0098
47 0.2427 PIK3R1,JUN,PTGS2,MAP3K8,TRAF5 0.0098
48 0.2455 PIK3R1,JUN,PPP3CC,VAV3 0.0065
49 0.2565 PIK3R1,JUN 0.0014
50 0.2565 AK4,AK5 0.0014
51 0.2565 GRIN2A,GRIK1,PPP3CC,ADCY2,PLA2G4A 0.0102
52 0.2573 PIK3R1,GRIN2A,JUN,VAV3,ADCY2,ADRB2,PDE4B 0.0179
53 0.2615 PIK3R1,JUN,VAV3,CTNNB1,CAPN2,COL4A2,COL4A1 0.018
54 0.2615 MEF2C,PIK3R1 0.0015
55 0.2615 JUN,RICTOR,CTNNB1 0.004
56 0.2615 PIK3R1,SGK1,GRB14 0.004
57 0.2615 CYFIP2,JUN,PIN1,PLA2G4A,PTPN2 0.0107
58 0.2615 PIK3R1,VAV3 0.0016
59 0.2615 PIK3R1,JUN,PPP3CC,VAV3 0.0072
60 0.2615 PIK3R1,JUN,IL6ST 0.0042
61 0.2615 PIK3R1,VAV3,PI4KA 0.0042
62 0.2615 NEDD4L,CTNNB1,PPP1R15A 0.0042
63 0.2615 ADCY2,SNAP29 0.0017
64 0.2615 RIN2,ROBO1,CTNNB1 0.0043
65 0.2615 PIK3R1,CACNA1E,SLC2A2 0.0043
66 0.2615 PIK3R1,VAV3,CSF2RA 0.0044
67 0.2615 GRIN2A,PTPRD 0.0018
68 0.2615 SEH1L,WAPL,CENPA,DYNC1I1,CENPI,CLASP1 0.0153
69 0.2615 PIK3R1,COL4A2,COL4A1 0.0046
70 0.2615 PIK3R1,IFNGR1,IL6ST 0.0046
71 0.2615 PIK3R1,CTNNB1 0.0019
72 0.2615 PIK3R1,JUN 0.0019
73 0.2615 PIK3R1,JUN 0.0019
74 0.2615 PIK3R1,JUN,ADCY2,COL4A2,COL4A1 0.0116
75 0.2615 SEH1L,WAPL,CENPA,DYNC1I1,CENPI,CLASP1 0.0156
76 0.2615 PIK3R1,JUN 0.002
77 0.2615 MEF2C,JUN,MAP3K8 0.0047
78 0.2615 JUN,PPP3CC,IFNGR1,IL4R 0.0082
79 0.2615 ADCY2,AKAP5,CACNA1E,SLC2A2 0.0082
80 0.2615 CYFIP2,JUN,CTNNB1 0.0048
81 0.2615 ADCY2 0.0003
82 0.2615 ADCY2,SNAP29 0.0021
83 0.2615 PIK3R1,HHAT 0.0021
84 0.2615 MEF2C,PIK3R1 0.0021
85 0.2615 IL13RA1,IL4R,IL6ST 0.0049
86 0.2615 ADCY2,PTGS2,PLA2G4A 0.0049
87 0.2615 FZD3,FZD9,CTNNB1 0.0049
88 0.2615 PIK3R1,ADRB2 0.0021
89 0.2615 PIK3R1,PIN1 0.0021
90 0.2615 MEF2C,CTNNB1 0.0021
91 0.2615 CYFIP2,WIPF3,SEH1L,VAV3,CENPA,DYNC1I1,CENPI,CTNNB1,CLASP1 0.0302
92 0.2615 PIK3R1,VAV3,ADCY2,CCL4L1,ELMO1,CCL3L3 0.0167
93 0.2615 FBXW7,PIN1 0.0022
94 0.2615 PIK3R1,JUN 0.0022
95 0.2615 PIK3R1,JUN 0.0022
96 0.2615 FZD3,JUN,FZD9,PPP3CC,CTNNB1 0.0128
97 0.2615 GRIN2A,GRIK1,ADCY2,AKAP5,CACNG2 0.0128
98 0.2615 PIK3R1,ADCY2,TRPV4,PLA2G4A 0.0088
99 0.2615 PIK3R1,JUN,ADCY2,OPRM1 0.0089
100 0.2615 PIK3R1,JUN 0.0023
101 0.2615 NKX2-2,SLC2A2 0.0023
102 0.2615 PIK3R1,JUN 0.0023
103 0.2615 NEDD4L,PIK3R1,ELMO1 0.0054
104 0.2615 FZD3,FZD9,ADCY2,CTNNB1 0.009
105 0.2615 PIK3R1,JUN,COL4A2,COL4A1 0.009
表7.a2
   基因集 基因集中之數字 來自清單
106 乳癌(K) 146 5
107 嘧啶代謝(P) 4 1
108 腸道吸收(R) 4 1
109 纈胺酸、白胺酸及異白胺酸生物合成(K) 4 1
110 磷脂酶c信號傳導路徑(B) 4 1
111 鐸受體信號傳導路徑(P) 4 1
112 ifn γ信號傳導路徑(B) 4 1
113 β1腎上腺素激導性受體信號傳導路徑(P) 27 2
114 肥大細胞中之Fc-ε受體I信號傳導(N) 62 3
115 內皮素(N) 62 3
116 大腸直腸癌(K) 62 3
117 卻格司氏病(美國錐蟲病) (K) 104 4
118 由VEGFR1及VEGFR2介導之信號傳導事件(N) 63 3
119 LPA受體介導之事件(N) 63 3
120 Wnt信號傳導網絡(N) 28 2
121 核小體組裝(R) 29 2
122 發炎性腸病(IBD) (K) 65 3
123 藉由CD28家族進行共刺激(R) 65 3
124 細胞老化(K) 154 5
125 界面活性劑代謝(R) 30 2
126 CDC42活性之調節(N) 30 2
127 黏附分子黏附路徑(N) 30 2
128 介白素-17信號傳導(R) 67 3
129 腎細胞癌(K) 67 3
130 HTLV-I感染(K) 258 7
131 安非他明成癮(K) 68 3
132 β細胞發育之調節(R) 31 2
133 三葉因子引發黏膜癒合(B) 31 2
134 Huma乳頭瘤病毒感染(K) 313 8
135 Fc γ受體(FCGR)依賴性噬菌作用(R) 159 5
136 軸突引導因子介導之信號傳導事件(N) 32 2
137 G蛋白β：γ信號傳導(R) 32 2
138 AP-1轉錄因子網絡(N) 70 3
139 CDC42信號傳導事件(N) 70 3
140 Fc ε RI信號傳導路徑(K) 70 3
141 壞死性凋亡(K) 162 5
142 N-鈣黏蛋白信號傳導事件(N) 33 2
143 經由pyk2依賴性信號傳導進行血管緊張素ii介導之jnk路徑活化(B) 33 2
144 藉由bZIP轉錄因子進行轉錄調節(P) 6 1
145 一般轉錄調節(P) 6 1
146 d4gdi信號傳導路徑(B) 6 1
147 細胞己糖轉運(R) 6 1
148 Arf6遷移事件(N) 34 2
149 IL1介導之信號傳導事件(N) 34 2
150 利什曼體病(K) 73 3
151 cGMP-PKG信號傳導路徑(K) 168 5
152 Arf6信號傳導事件(N) 35 2
153 p73轉錄因子網絡(N) 75 3
154 藉由akt使gsk3失活造成b-連環蛋白在肺泡巨噬細胞中之聚集(B) 36 2
155 阿茲海默症(K) 171 5
156 神經活性配體-受體相互作用(K) 278 7
157 由信號蛋白介導之軸突導引(P) 7 1
158 顫蛋白信號傳導路徑(R) 7 1
159 GMCSF介導之信號傳導事件(N) 37 2
160 心臟之nfat及肥大(B) 37 2
161 上皮細胞之細菌侵入(K) 78 3
162 核β連環蛋白信號傳導及靶基因轉錄之調節(N) 79 3
163 RAC1活性之調節(N) 38 2
164 介白素-3、介白素-5及GM-CSF信號傳導(R) 38 2
165 軸突導引(K) 177 5
166 藉由Ret酪胺酸激酶調節的信號傳導事件(N) 39 2
167 b細胞免疫應答之yaci及bcma刺激(B) 8 1
168 伴隨蛋白調節干擾素信號傳導路徑(B) 8 1
169 巨噬細胞中之百日咳毒素不敏感ccr5信號傳導(B) 8 1
170 藉由共抑制物mitr進行肌生成之信號依賴性調節(B) 8 1
171 微血管內皮細胞中之tsp-1誘導之細胞凋亡(B) 8 1
172 化學癌發生(K) 82 3
173 G α (i)信號傳導事件(R) 345 8
174 介白素-2家族信號傳導(R) 40 2
175 細胞凋亡之內在路徑(R) 41 2
176 移植物抗宿主病(K) 41 2
177 破骨細胞分化(K) 132 4
178 離子通道及其在血管內皮中之功能作用(B) 42 2
179 E-鈣黏蛋白黏附接合之穩定及擴增(N) 42 2
180 Apelin信號傳導路徑(K) 136 4
181 t細胞活化中之il-2受體β鏈(B) 44 2
182 轉譯後修飾:合成GPI錨定蛋白質(R) 89 3
183 半胱胺酸及甲硫胺酸代謝(K) 45 2
184 Notch及Wnt信號傳導中之早老素作用(N) 45 2
185 基礎轉錄因子(K) 45 2
186 蛋白質消化及吸收(K) 90 3
187 類風濕性關節炎(K) 90 3
188 唾液分泌物(K) 90 3
189 GP1b-IX-V活化信號傳導(R) 10 1
190 cxcr4信號傳導路徑(B) 10 1
191 骨骼礦化之調節因子(B) 10 1
192 5HT3型受體介導之信號傳導路徑(P) 10 1
193 細胞凋亡(K) 140 4
194 嗎啡鹼成癮(K) 91 3
195 淋巴球中之經鈣調神經磷酸酶調節的NFAT依賴性轉錄(N) 46 2
196 碳水化合物消化及吸收(K) 46 2
197 TNF受體信號傳導路徑(N) 46 2
198 GnRH信號傳導路徑(K) 92 3
199 FGF信號傳導路徑(N) 47 2
200 Fc γ R介導之噬菌作用(K) 93 3
201 IL-17信號傳導路徑(K) 93 3
202 il-7信號轉導(B) 11 1
203 t細胞受體信號傳導路徑(B) 48 2
204 FoxO家族信號傳導(N) 48 2
205 NF-κ B 信號傳導路徑(K) 95 3
206 異三聚體G蛋白信號傳導路徑-Gi α及Gs α介導之路徑(P) 147 4
207 高爾基體內及逆行高爾基體-至-ER運輸(R) 147 4
208 可卡因成癮(K) 49 2
209 晝夜節律(K) 96 3
210 病毒癌發生(K) 203 5
表7.b1
   P值 FDR 節點 基因集中蛋白質之比率
106 0.0524 0.2615 PIK3R1,FZD3,JUN,FZD9,CTNNB1 0.0131
107 0.0536 0.2615 DPYSL5 0.0004
108 0.0536 0.2615 SLC2A2 0.0004
109 0.0536 0.2615 BCAT2 0.0004
110 0.0536 0.2615 PIK3R1 0.0004
111 0.0536 0.2615 MAP3K8 0.0004
112 0.0536 0.2615 IFNGR1 0.0004
113 0.0539 0.2615 ADCY2,SNAP29 0.0024
114 0.0549 0.2615 PIK3R1,JUN,PLA2G4A 0.0055
115 0.0549 0.2615 JUN,ADCY2,PLA2G4A 0.0055
116 0.0549 0.2615 PIK3R1,JUN,CTNNB1 0.0055
117 0.0565 0.2615 PIK3R1,JUN,IFNGR1,CCL3L3 0.0093
118 0.0571 0.2615 PIK3R1,CTNNB1,PTPN2 0.0056
119 0.0571 0.2615 PIK3R1,JUN,ADCY2 0.0056
120 0.0575 0.2615 FZD9,ATP6AP2 0.0025
121 0.0611 0.2615 CENPA,CENPI 0.0026
122 0.0615 0.2615 JUN,IFNGR1,IL4R 0.0058
123 0.0615 0.2615 PIK3R1,RICTOR,MAP3K8 0.0058
124 0.0628 0.2615 PIK3R1,GADD45G,PPP3CC,CAPN2,TRPV4 0.0138
125 0.0648 0.2615 CSF2RA,ADGRF5 0.0027
126 0.0648 0.2615 VAV3,DOCK11 0.0027
127 0.0648 0.2615 PIK3R1,CTNNB1 0.0027
128 0.066 0.2615 MEF2C,JUN,MAP3K8 0.006
129 0.066 0.2615 PIK3R1,JUN,ARNT2 0.006
130 0.0671 0.2615 PIK3R1,FZD3,JUN,FZD9,PPP3CC,ADCY2,CTNNB1 0.0231
131 0.0684 0.2615 GRIN2A,JUN,PPP3CC 0.0061
132 0.0686 0.2615 NKX2-2,SLC2A2 0.0028
133 0.0686 0.2615 PIK3R1,CTNNB1 0.0028
134 0.0689 0.2615 PIK3R1,FZD3,FZD9,NFX1,PTGS2,CTNNB1,COL4A2,COL4A1 0.028
135 0.0699 0.2615 CYFIP2,WIPF3,PIK3R1,VAV3,ELMO1 0.0142
136 0.0725 0.2615 PIK3R1,ELMO1 0.0029
137 0.0725 0.2615 PIK3R1,CSF2RA 0.0029
138 0.0732 0.2615 JUN,CTNNB1,BAG1 0.0063
139 0.0732 0.2615 PIK3R1,JUN,CTNNB1 0.0063
140 0.0732 0.2615 PIK3R1,VAV3,PLA2G4A 0.0063
141 0.0744 0.2615 IFNGR1,CAPN2,PLA2G4A,TRAF5,CHMP5 0.0145
142 0.0764 0.2615 PIK3R1,CTNNB1 0.0029
143 0.0764 0.2615 MEF2C,JUN 0.0029
144 0.0793 0.2615 GTF2E1 0.0005
145 0.0793 0.2615 GTF2E1 0.0005
146 0.0793 0.2615 JUN 0.0005
147 0.0793 0.2615 SLC2A2 0.0005
148 0.0804 0.2615 CTNNB1,ADRB2 0.003
149 0.0804 0.2615 PIK3R1,JUN 0.003
150 0.0806 0.2615 JUN,IFNGR1,PTGS2 0.0065
151 0.0837 0.2615 MEF2C,PIK3R1,PPP3CC,ADCY2,ADRB2 0.015
152 0.0845 0.2615 IPCEF1,ADRB2 0.0031
153 0.0857 0.2615 NEDD4L,IL4R,PIN1 0.0067
154 0.0886 0.2615 PIK3R1,CTNNB1 0.0032
155 0.0886 0.2615 GRIN2A,RYR3,PPP3CC,CAPN2,UQCRFS1 0.0153
156 0.0908 0.2615 GRIN2A,GRIK1,CHRM5,ADRB2,THRB,GRID1,OPRM1 0.0249
157 0.0919 0.2615 DPYSL5 0.0006
158 0.0919 0.2615 DAB1 0.0006
159 0.0928 0.2615 PIK3R1,CSF2RA 0.0033
160 0.0928 0.2615 MEF2C,PIK3R1 0.0033
161 0.0937 0.2615 PIK3R1,CTNNB1,ELMO1 0.007
162 0.0964 0.2615 JUN,CTNNB1,TNIK 0.0071
163 0.097 0.2615 VAV3,ELMO1 0.0034
164 0.097 0.2615 PIK3R1,CSF2RA 0.0034
165 0.0989 0.2615 DPYSL5,PIK3R1,FZD3,ROBO1,PPP3CC 0.0158
166 0.1013 0.2615 PIK3R1,JUN 0.0035
167 0.1043 0.2615 TNFRSF17 0.0007
168 0.1043 0.2615 IFNGR1 0.0007
169 0.1043 0.2615 JUN 0.0007
170 0.1043 0.2615 MEF2C 0.0007
171 0.1043 0.2615 JUN 0.0007
172 0.1048 0.2615 CYP1B1,MGST1,PTGS2 0.0073
173 0.1052 0.2615 PPP3CC,ADCY2,CAMKMT,PDE4B,PLA2G4A,OPRM1,SLC24A1,APLN 0.0308
174 0.1057 0.2615 PIK3R1,CSF2RA 0.0036
175 0.1101 0.2615 TP53BP2,PPP3CC 0.0037
176 0.1101 0.2615 KLRC1,KLRD1 0.0037
177 0.1103 0.2615 PIK3R1,JUN,PPP3CC,IFNGR1 0.0118
178 0.1145 0.2615 ADRB2,TRPV4 0.0038
179 0.1145 0.2615 CYFIP2,CTNNB1 0.0038
180 0.1194 0.2615 MEF2C,RYR3,ADCY2,APLN 0.0122
181 0.1235 0.2615 PIK3R1,PIN1 0.0039
182 0.1253 0.2615 CD109,CNTN5,XPNPEP2 0.008
183 0.1281 0.2615 MAT1A,BCAT2 0.004
184 0.1281 0.2615 JUN,CTNNB1 0.004
185 0.1281 0.2615 GTF2E1,TAF2 0.004
186 0.1284 0.2615 COL4A2,COL4A1,XPNPEP2 0.008
187 0.1284 0.2615 ATP6V1G1,JUN,CCL3L3 0.008
188 0.1284 0.2615 RYR3,ADCY2,ADRB2 0.008
189 0.1287 0.2615 PIK3R1 0.0009
190 0.1287 0.2615 PIK3R1 0.0009
191 0.1287 0.2615 COL4A2 0.0009
192 0.1287 0.2615 SNAP29 0.0009
193 0.1288 0.2615 PIK3R1,JUN,GADD45G,CAPN2 0.0125
194 0.1315 0.2615 ADCY2,PDE4B,OPRM1 0.0081
195 0.1327 0.2615 JUN,PTGS2 0.0041
196 0.1327 0.2615 PIK3R1,SLC2A2 0.0041
197 0.1327 0.2615 MAP4K3,TNIK 0.0041
198 0.1345 0.2615 JUN,ADCY2,PLA2G4A 0.0082
199 0.1374 0.2615 PIK3R1,JUN 0.0042
200 0.1377 0.2615 PIK3R1,VAV3,PLA2G4A 0.0083
201 0.1377 0.2615 JUN,PTGS2,TRAF5 0.0083
202 0.1406 0.2615 PIK3R1 0.001
203 0.142 0.2615 PIK3R1,JUN 0.0043
204 0.142 0.2615 SGK1,CTNNB1 0.0043
205 0.144 0.2615 PTGS2,CCL4L1,TRAF5 0.0085
206 0.146 0.2615 ADCY2,CHRM5,ADRB2,OPRM1 0.0131
207 0.146 0.2615 DYNC1I1,SNAP29,PLA2G4A,GALNT2 0.0131
208 0.1468 0.2615 GRIN2A,JUN 0.0044
209 0.1472 0.2615 GRIN2A,RYR3,ADCY2 0.0086
210 0.1497 0.2615 PIK3R1,JUN,IL6ST,GTF2E1,TRAF5 0.0181
表7.b2
   基因集 基因集中之數目 來自清單
211 心肌細胞中之腎上腺素信號傳導(K) 149 4
212 血管生成素受體Tie2介導之信號傳導(N) 50 2
213 carm1及雌激素受體之調節(B) 12 1
214 胰島素信號傳導路徑(B) 12 1
215 trka受體信號傳導路徑(B) 12 1
216 藉由轉錄調節因子dream壓制疼痛感覺(B) 12 1
217 分支鏈胺基酸分解代解(R) 12 1
218 磷脂酶c-ε路徑(B) 12 1
219 信號調節蛋白家族相互作用(R) 12 1
220 經由nf-kb進行促紅細胞生成素介導之神經保護(B) 12 1
221 黃黴毒素活化及解毒(R) 12 1
222 內分泌抗性(K) 98 3
223 阿米巴病(K) 98 3
224 癌症中之蛋白聚糖(K) 205 5
225 藉由非受體酪胺酸激酶進行信號傳導(R) 51 2
226 肌肉萎縮性側索硬化(ALS) (K) 51 2
227 鈣黏蛋白信號傳導路徑(P) 100 3
228 鈣調神經磷酸酶依賴性NFAT信號傳導在淋巴球中之作用(N) 52 2
229 子宮內膜癌(K) 52 2
230 藉由MET進行信號傳導(R) 52 2
231 癌症中之膽鹼代謝(K) 101 3
232 人類巨細胞病毒及map激酶路徑(B) 13 1
233 血管收縮素原至血管緊張素之代謝(R) 13 1
234 硫胺基酸代謝(R) 13 1
235 鎘誘導dna合成及巨噬細胞之增殖(B) 13 1
236 th1發育中il12及stat4依賴性信號傳導路徑(B) 13 1
237 b細胞存活路徑(B) 13 1
238 來自igf-1r信號傳導之多個抗凋亡路徑引起不良磷酸化(B) 13 1
239 Hippo信號傳導路徑(K) 154 4
240 鐵攝取及轉運(R) 53 2
241 Rap1信號傳導路徑(K) 212 5
242 升糖素信號傳導路徑(K) 103 3
243 IL2介導之信號傳導事件(N) 54 2
244 整合素信號傳導路徑(P) 158 4
245 LGI-ADAM相互作用(R) 14 1
246 il 4信號傳導路徑(B) 14 1
247 41bb依賴性免疫反應(B) 14 1
248 IL5介導之信號傳導事件(N) 14 1
249 有絲分裂分裂末期/細胞質分裂(R) 14 1
250 氧化應力經由nrf2誘導基因表現(B) 14 1
251 非典型NF-κB路徑(N) 14 1
252 CD4+ TCR路徑中之Ras信號傳導(N) 14 1
253 介白素-12家族信號傳導(R) 55 2
254 神經突增生NCAM信號傳導(R) 56 2
255 藉由乙型肝炎病毒之hbx進行鈣信號傳導(B) 15 1
256 鞘醣脂生物合成-神經節系列(K) 15 1
257 atm信號傳導路徑(B) 15 1
258 干擾素-γ信號傳導路徑(P) 15 1
259 異三聚體G蛋白信號傳導路徑-Gq α及Go α介導之路徑(P) 108 3
260 抗胰島素症(K) 109 3
261 PIP3活化AKT信號傳導(R) 222 5
262 離胺酸分解(K) 59 2
263 化合物之II期共軛(R) 59 2
264 B細胞活化(P) 59 2
265 阿茲海默症-早老素路徑(P) 111 3
266 膽鹼激導性突觸(K) 111 3
267 LPA4介導之信號傳導事件(N) 16 1
268 RAF非依賴性MAPK1/3活化(R) 16 1
269 akt信號傳導路徑(B) 16 1
270 igf-1受體及壽命(B) 16 1
271 菸鹼乙醯膽鹼受體在細胞凋亡之調節中的作用(B) 16 1
272 pi3k亞單位p85在調節肌蛋白組織及細胞遷移中之作用(B) 16 1
273 G α (12/13)信號傳導事件(R) 60 2
274 雄激素受體活性之共調節(N) 60 2
275 帕金森病(Parkinson disease) (P) 61 2
276 pten依賴性細胞週期停滯及細胞凋亡(B) 17 1
277 蛋白質甲基化(R) 17 1
278 心血管系統中之低氧誘導因子(B) 17 1
279 信號擴增(R) 17 1
280 二十碳四烯酸代謝(K) 62 2
281 經驗證核雌激素受體α網絡(N) 62 2
282 白細胞經內皮遷移(K) 116 3
283 smrt共抑制物之map激酶失活(B) 18 1
284 β連環蛋白之分解(N) 18 1
285 泛酸鹽及CoA生物合成(K) 18 1
286 2-氧代羧酸代謝(K) 18 1
287 S1P1路徑(N) 18 1
288 mets對巨噬細胞分化之影響(B) 18 1
289 pgc-1a之調節(B) 18 1
290 壽命調節路徑-多物種(K) 64 2
291 視網膜母細胞瘤蛋白質之調節(N) 64 2
292 嘌呤代謝(K) 175 4
293 甲狀腺激素信號傳導路徑(K) 118 3
294 腎素分泌物(K) 65 2
295 PI代謝(R) 65 2
296 受體型酪胺酸-蛋白質磷酸酶(R) 19 1
297 囊性纖維化跨膜傳導調節蛋白(cftr)及β2腎上腺素激導性受體(b2ar)路徑(B) 19 1
298 腫瘤抑制劑arf抑制核糖體生物合成(B) 19 1
299 前HOX基因在後腦發育中在早期胚胎發生期間的活化(R) 66 2
300 HIF-1-α轉錄因子網絡(N) 66 2
301 晝夜節律(R) 67 2
302 癌症中之中央碳代謝(K) 67 2
303 長時程增強(K) 67 2
304 naïve CD4+ T細胞中之TCR信號傳導 (N) 67 2
305 ISG15抗病毒機制(R) 67 2
306 血小板活化(K) 122 3
307 幽門螺旋桿菌感染中之上皮細胞信號傳導(K) 68 2
308 典型Wnt信號傳導路徑(N) 20 1
309 tnf/應力相關信號傳導(B) 20 1
310 一個葉酸碳池(K) 20 1
311 T細胞活化期間的共刺激信號(B) 20 1
312 不良磷酸化之調節(B) 20 1
313 RNA聚合酶II轉錄(R) 826 14
314 egf信號傳導路徑(B) 21 1
315 β2腎上腺素激導性受體信號傳導路徑(P) 21 1
表7.c1
   P值 FDR 節點 基因集中蛋白質之比率
211 0.151 0.2615 PIK3R1,ADCY2,ADRB2,CACNG2 0.0133
212 0.1515 0.2615 PIK3R1,GRB14 0.0045
213 0.1523 0.2615 MEF2C 0.0011
214 0.1523 0.2615 PIK3R1 0.0011
215 0.1523 0.2615 PIK3R1 0.0011
216 0.1523 0.2615 JUN 0.0011
217 0.1523 0.2615 BCAT2 0.0011
218 0.1523 0.2615 ADRB2 0.0011
219 0.1523 0.2615 FYB1 0.0011
220 0.1523 0.2615 JUN 0.0011
221 0.1523 0.2615 MGST1 0.0011
222 0.1537 0.2615 PIK3R1,JUN,ADCY2 0.0088
223 0.1537 0.2615 PIK3R1,COL4A2,COL4A1 0.0088
224 0.154 0.2615 PIK3R1,FZD3,FZD9,CTNNB1,PDCD4 0.0183
225 0.1563 0.2615 ELMO1,KHDRBS2 0.0046
226 0.1563 0.2615 GRIN2A,PPP3CC 0.0046
227 0.1602 0.2615 FZD3,FZD9,CTNNB1 0.0089
228 0.1611 0.2615 AKAP5,MAP3K8 0.0046
229 0.1611 0.2615 PIK3R1,CTNNB1 0.0046
230 0.1611 0.2615 PIK3R1,PTPN2 0.0046
231 0.1635 0.2615 PIK3R1,JUN,PLA2G4A 0.009
232 0.1639 0.2615 PIK3R1 0.0012
233 0.1639 0.2615 ATP6AP2 0.0012
234 0.1639 0.2615 MAT1A 0.0012
235 0.1639 0.2615 JUN 0.0012
236 0.1639 0.2615 JUN 0.0012
237 0.1639 0.2615 PIK3R1 0.0012
238 0.1639 0.2615 PIK3R1 0.0012
239 0.164 0.2615 TP53BP2,FZD3,FZD9,CTNNB1 0.0138
240 0.1659 0.2615 ATP6V1G1,FBXL5 0.0047
241 0.1695 0.2615 PIK3R1,GRIN2A,RAPGEF5,ADCY2,CTNNB1 0.019
242 0.1702 0.2615 PPP3CC,ADCY2,SLC2A2 0.0092
243 0.1708 0.2615 PIK3R1,JUN 0.0048
244 0.1746 0.2615 PIK3R1,COL4A2,COL4A1,ELMO1 0.0141
245 0.1754 0.2615 CACNG2 0.0013
246 0.1754 0.2615 IL4R 0.0013
247 0.1754 0.2615 JUN 0.0013
248 0.1754 0.2615 PIK3R1 0.0013
249 0.1754 0.2615 WAPL 0.0013
250 0.1754 0.2615 JUN 0.0013
251 0.1754 0.2615 PIK3R1 0.0013
252 0.1754 0.2615 MAP3K8 0.0013
253 0.1757 0.2615 IL6ST,PDCD4 0.0049
254 0.1806 0.2615 COL4A2,COL4A1 0.005
255 0.1867 0.2615 JUN 0.0013
256 0.1867 0.2615 ST6GALNAC3 0.0013
257 0.1867 0.2615 JUN 0.0013
258 0.1867 0.2615 IFNGR1 0.0013
259 0.1872 0.2615 CHRM5,CACNA1E,OPRM1 0.0097
260 0.1907 0.2615 PPP1R3B,PIK3R1,SLC2A2 0.0097
261 0.1926 0.2615 PIK3R1,JUN,MECOM,RICTOR,FRK 0.0198
262 0.1954 0.2615 PRDM2,CAMKMT 0.0053
263 0.1954 0.2615 MGST1,MAT1A 0.0053
264 0.1954 0.2615 JUN,VAV3 0.0053
265 0.1976 0.2615 FZD3,FZD9,CTNNB1 0.0099
266 0.1976 0.2615 PIK3R1,ADCY2,CHRM5 0.0099
267 0.1978 0.2615 ADCY2 0.0014
268 0.1978 0.2615 IL6ST 0.0014
269 0.1978 0.2615 PIK3R1 0.0014
270 0.1978 0.2615 PIK3R1 0.0014
271 0.1978 0.2615 PIK3R1 0.0014
272 0.1978 0.2615 PIK3R1 0.0014
273 0.2004 0.2615 PIK3R1,VAV3 0.0054
274 0.2004 0.2615 VAV3,CTNNB1 0.0054
275 0.2054 0.2615 PRKN,FRK 0.0055
276 0.2088 0.2615 PIK3R1 0.0015
277 0.2088 0.2615 CAMKMT 0.0015
278 0.2088 0.2615 JUN 0.0015
279 0.2088 0.2615 PLA2G4A 0.0015
280 0.2104 0.2615 PTGS2,PLA2G4A 0.0055
281 0.2104 0.2615 JUN,KLRC3 0.0055
282 0.2153 0.2615 PIK3R1,VAV3,CTNNB1 0.0104
283 0.2196 0.2615 THRB 0.0016
284 0.2196 0.2615 CTNNB1 0.0016
285 0.2196 0.2615 BCAT2 0.0016
286 0.2196 0.2615 BCAT2 0.0016
287 0.2196 0.2615 PTGS2 0.0016
288 0.2196 0.2615 JUN 0.0016
289 0.2196 0.2615 MEF2C 0.0016
290 0.2205 0.2615 PIK3R1,ADCY2 0.0057
291 0.2205 0.2615 MEF2C,JUN 0.0057
292 0.2222 0.2615 ADCY2,AK4,AK5,PDE4B 0.0156
293 0.2224 0.2615 PIK3R1,CTNNB1,THRB 0.0105
294 0.2255 0.2615 PPP3CC,ADRB2 0.0058
295 0.2255 0.2615 PIK3R1,PI4KA 0.0058
296 0.2303 0.2615 PTPRD 0.0017
297 0.2303 0.2615 ADRB2 0.0017
298 0.2303 0.2615 PIK3R1 0.0017
299 0.2305 0.2615 JUN,MEIS1 0.0059
300 0.2305 0.2615 JUN,BHLHE41 0.0059
301 0.2356 0.2615 MEF2C,BHLHE41 0.006
302 0.2356 0.2615 PIK3R1,SLC2A2 0.006
303 0.2356 0.2615 GRIN2A,PPP3CC 0.006
304 0.2356 0.2615 FYB1,MAP3K8 0.006
305 0.2356 0.2615 SEH1L,PIN1 0.006
306 0.2369 0.2615 PIK3R1,ADCY2,PLA2G4A 0.0109
307 0.2407 0.2615 ATP6V1G1,JUN 0.0061
308 0.2409 0.2615 CTNNB1 0.0018
309 0.2409 0.2615 JUN 0.0018
310 0.2409 0.2615 MTHFD1 0.0018
311 0.2409 0.2615 PIK3R1 0.0018
312 0.2409 0.2615 PIK3R1 0.0018
313 0.2478 0.2615 NEDD4L,TP53BP2,JUN,INTS14,SGK1,RICTOR,CTNNB1,FBXW7,LIFR,GTF2E1,PIN1,THRB,E2F6,TAF2 0.0738
314 0.2513 0.2615 PIK3R1 0.0019
315 0.2513 0.2615 SNAP29 0.0019
表7.c2
   基因集 基因集中之數目 來自清單
316 生長激素信號傳導路徑(B) 21 1
317 β3腎上腺素激導性受體信號傳導路徑(P) 21 1
318 分段時鐘(B) 21 1
319 孕酮如何引發卵母細胞成熟(B) 21 1
320 催產素受體介導之信號傳導路徑(P) 21 1
321 細胞週期檢查點(R) 246 5
322 心律不整右心室心肌病(ARVC) (K) 72 2
323 催乳素信號傳導路徑(K) 72 2
324 ctcf：第一多價核因子(B) 22 1
325 內在凝血酶原活化路徑(B) 22 1
326 ras信號傳導路徑(B) 22 1
327 ras及ρ蛋白質對g1至s轉變之影響(B) 22 1
328 介白素-7信號傳導(R) 22 1
329 Nephrin家族相互作用(R) 22 1
330 藉由TGF-β受體複合物進行信號傳導(R) 73 2
331 化合物之I期功能化(R) 73 2
332 干擾素γ信號傳導(R) 73 2
333 慢性骨髓白血病(K) 73 2
334  RAB GEF將GTP交換成RAB上之GDP(R) 73 2
335 藉由細胞色素P450代謝異生物質(K) 74 2
336 藉由胰島素受體進行信號傳導(R) 74 2
337 水溶性維生素及輔因子之代謝(R) 74 2
338 心肌細胞中之alk (B) 23 1
339 pyk2與map激酶之間的相關性(B) 23 1
340 G α (z)信號傳導事件(R) 23 1
341 腎素-血管緊張素系統(K) 23 1
342 不飽和脂肪酸之生物合成(K) 23 1
343 eif-4e及p70s6激酶之調節(B) 23 1
344 視覺信號轉導：Rods (N) 23 1
345 鉑耐藥性(K) 75 2
346 胺基酸之生物合成(K) 75 2
347 氧化磷酸化(K) 133 3
348 淋巴細胞與非淋巴細胞之間的免疫調節相互作用(R) 194 4
349 FoxO信號傳導路徑(K) 134 3
350 甘油磷脂生物合成(R) 76 2
351 經由HIF活化之低氧應答(P) 24 1
352 轉錄因子creb及其胞外信號(B) 24 1
353 p53路徑回饋環2(P) 24 1
354 Ephrin B逆向信號傳導(N) 24 1
355 骨胳肌肉肥大係經由akt-mtor路徑調節(B) 24 1
356 α9 β1整合素信號傳導事件(N) 24 1
357 核SMAD2/3信號傳導之調節(N) 77 2
358 內吞作用(K) 260 5
359 胞外基質組織(R) 261 5
360 心肌收縮(K) 78 2
361 對熱應力之細胞反應(R) 78 2
362 糖皮質激素受體調節網絡(N) 78 2
363 淋巴內皮中之VEGFR3信號傳導(N) 25 1
364 α-次亞麻油酸代謝(K) 25 1
365 脂肪酸伸長(K) 25 1
366 非基因雄激素信號傳導(N) 25 1
367 促腎上腺皮質激素釋出因子受體信號傳導路徑(P) 25 1
368 腎臟足細胞中之Nephrin/Neph1信號傳導(N) 25 1
369 藉由RNA進行基因沈默(R) 79 2
370 藉由ROBO受體進行信號傳導(R) 201 4
371 bcr信號傳導路徑(B) 26 1
372 5HT2型受體介導之信號傳導路徑(P) 26 1
373 IL3介導之信號傳導事件(N) 26 1
374 生物活性肽誘導之信號傳導路徑(B) 26 1
375 用其他核受體進行RXR及RAR異二聚化(N) 26 1
376 藉由pitx2進行轉錄之多步驟調節(B) 26 1
377 抗利尿素經由水孔蛋白調節腎水內穩定(R) 26 1
378 IL27介導之信號傳導事件(N) 26 1
379 camp依賴性蛋白激酶pka之活化(B) 26 1
380 gpcr減感作用中之√ü-抑制蛋白(B) 26 1
381 Wnt信號傳導路徑(P) 267 5
382 埃-巴二氏病毒感染(K) 204 4
383 凝血酶信號傳導及蛋白酶活化受體(B) 27 1
384 VEGFR1特定信號(N) 27 1
385 p38 MAPK信號傳導路徑(N) 27 1
386 三酸甘油酯代謝(R) 27 1
387 收集管道酸分泌物(K) 27 1
388 ECM-受體相互作用(K) 82 2
389 鐸樣受體級聯(R) 143 3
390 染色質組織(R) 206 4
391 味覺轉導(K) 83 2
392 磷脂酶D信號傳導路徑(K) 144 3
393 √ü-抑制蛋白在活化及靶向map激酶中之作用(B) 28 1
394 神經元遷移及發育中之平腦症基因(LIS1) (N) 28 1
395 erbb2在信號轉導及腫瘤學中之作用(B) 28 1
396 光轉導(K) 28 1
397 由STAT5介導之IL2信號傳導事件(N) 28 1
398 vegf低氧及血管新生(B) 28 1
399 背-腹軸形成(K) 28 1
400 胰島素分泌物(K) 85 2
401 甲狀腺癌(K) 29 1
402 線粒體(R) 29 1
403 亞麻油酸代謝(K) 29 1
404 CD40/CD40L信號傳導(N) 29 1
405 PI3K-Akt信號傳導路徑(K) 341 6
406 tRNA胺醯化(R) 30 1
407 erk及pi-3激酶為角膜上皮中膠原蛋白結合所必需(B) 30 1
408 ifn β增強子處的資訊處理路徑(B) 30 1
409 wnt信號傳導路徑(B) 30 1
410 IGF1路徑(N) 30 1
411 α-突觸核蛋白信號傳導(N) 30 1
412 肌蛋白細胞骨架之調節(K) 214 4
413 ErbB信號傳導路徑(K) 88 2
414 非酒精性脂肪肝病(NAFLD) (K) 151 3
415 前列腺癌(K) 89 2
416 晝夜節律(K) 31 1
417 Aurora A信號傳導(N) 31 1
418 由STAT4介導之IL12信號傳導(N) 31 1
419 磷脂作為信號傳導中間物(B) 31 1
420 黏蛋白型O-聚糖生物合成(K) 31 1
表7.d1
   P值 FDR 節點 基因集中蛋白質之比率
316 0.2513 0.2615 PIK3R1 0.0019
317 0.2513 0.2615 SNAP29 0.0019
318 0.2513 0.2615 CTNNB1 0.0019
319 0.2513 0.2615 PIN1 0.0019
320 0.2513 0.2615 SNAP29 0.0019
321 0.252 0.2615 SEH1L,CENPA,DYNC1I1,CENPI,CLASP1 0.022
322 0.261 0.2615 CTNNB1,CACNG2 0.0064
323 0.261 0.2615 PIK3R1,SLC2A2 0.0064
324 0.2615 0.2615 PIK3R1 0.002
325 0.2615 0.2615 COL4A2 0.002
326 0.2615 0.2615 PIK3R1 0.002
327 0.2615 0.2615 PIK3R1 0.002
328 0.2615 0.2615 CRLF2 0.002
329 0.2615 0.2615 PIK3R1 0.002
330 0.2661 0.2661 NEDD4L,PPP1R15A 0.0065
331 0.2661 0.2661 CYP1B1,ARNT2 0.0065
332 0.2661 0.2661 IFNGR1,PTPN2 0.0065
333 0.2661 0.2661 PIK3R1,MECOM 0.0065
334 0.2661 0.2661 RIN2,DENND4A 0.0065
335 0.2711 0.2711 CYP1B1,MGST1 0.0066
336 0.2711 0.2711 ATP6V1G1,PIK3R1 0.0066
337 0.2711 0.2711 MTHFD1,PTGS2 0.0066
338 0.2716 0.2716 MEF2C 0.0021
339 0.2716 0.2716 JUN 0.0021
340 0.2716 0.2716 ADCY2 0.0021
341 0.2716 0.2716 ATP6AP2 0.0021
342 0.2716 0.2716 HACD3 0.0021
343 0.2716 0.2716 PIK3R1 0.0021
344 0.2716 0.2716 SLC24A1 0.0021
345 0.2762 0.2762 MGST1,PIK3R1 0.0067
346 0.2762 0.2762 MAT1A,BCAT2 0.0067
347 0.2774 0.2774 ATP6V1G1,PPA2,UQCRFS1 0.0119
348 0.2788 0.2788 CXADR,KLRK1,KLRC1,KLRD1 0.0173
349 0.2811 0.2811 PIK3R1,GADD45G,SGK1 0.012
350 0.2813 0.2813 DGAT2,PLA2G4A 0.0068
351 0.2816 0.2816 PIK3R1 0.0021
352 0.2816 0.2816 PIK3R1 0.0021
353 0.2816 0.2816 CTNNB1 0.0021
354 0.2816 0.2816 PIK3R1 0.0021
355 0.2816 0.2816 PIK3R1 0.0021
356 0.2816 0.2816 CSF2RA 0.0021
357 0.2864 0.2864 MEF2C,JUN 0.0069
358 0.2886 0.2886 WIPF3,NEDD4L,ADRB2,DNAJC6,CHMP5 0.0232
359 0.2913 0.2913 CAPN2,ADAM19,COL4A2,COL4A1,TLL1 0.0233
360 0.2914 0.2914 UQCRFS1,CACNG2 0.007
361 0.2914 0.2914 SEH1L,BAG1 0.007
362 0.2914 0.2914 JUN,SGK1 0.007
363 0.2914 0.2914 PIK3R1 0.0022
364 0.2914 0.2914 PLA2G4A 0.0022
365 0.2914 0.2914 HACD3 0.0022
366 0.2914 0.2914 PIK3R1 0.0022
367 0.2914 0.2914 SNAP29 0.0022
368 0.2914 0.2914 JUN 0.0022
369 0.2965 0.2965 SEH1L,PIWIL2 0.0071
370 0.3002 0.3002 GSPT1,ROBO1,AKAP5,CLASP1 0.018
371 0.3012 0.3012 JUN 0.0023
372 0.3012 0.3012 SNAP29 0.0023
373 0.3012 0.3012 PIK3R1 0.0023
374 0.3012 0.3012 PIK3R1 0.0023
375 0.3012 0.3012 THRB 0.0023
376 0.3012 0.3012 CTNNB1 0.0023
377 0.3012 0.3012 ADCY2 0.0023
378 0.3012 0.3012 IL6ST 0.0023
379 0.3012 0.3012 ADRB2 0.0023
380 0.3012 0.3012 ADRB2 0.0023
381 0.3073 0.3073 FZD3,FZD9,PPP3CC,CTNNB1,CDH9 0.0239
382 0.3095 0.3095 PIK3R1,JUN,GTF2E1,TRAF5 0.0182
383 0.3107 0.3107 PIK3R1 0.0024
384 0.3107 0.3107 PIK3R1 0.0024
385 0.3107 0.3107 GADD45G 0.0024
386 0.3107 0.3107 DGAT2 0.0024
387 0.3107 0.3107 ATP6V1G1 0.0024
388 0.3117 0.3117 COL4A2,COL4A1 0.0073
389 0.3147 0.3147 MEF2C,JUN,MAP3K8 0.0128
390 0.3157 0.3157 ZZZ3,KDM8,MECOM,PRMT7 0.0184
391 0.3167 0.3167 SCNN1G,SCNN1B 0.0074
392 0.3185 0.3185 PIK3R1,ADCY2,PLA2G4A 0.0129
393 0.3202 0.3202 ADRB2 0.0025
394 0.3202 0.3202 DAB1 0.0025
395 0.3202 0.3202 PIK3R1 0.0025
396 0.3202 0.3202 SLC24A1 0.0025
397 0.3202 0.3202 PIK3R1 0.0025
398 0.3202 0.3202 PIK3R1 0.0025
399 0.3202 0.3202 PIWIL2 0.0025
400 0.3268 0.3268 ADCY2,SLC2A2 0.0076
401 0.3295 0.3295 CTNNB1 0.0026
402 0.3295 0.3295 PRKN 0.0026
403 0.3295 0.3295 PLA2G4A 0.0026
404 0.3295 0.3295 JUN 0.0026
405 0.3297 0.3297 PIK3R1,OSMR,SGK1,IL4R,COL4A2,COL4A1 0.0305
406 0.3387 0.3387 PPA2 0.0027
407 0.3387 0.3387 PIK3R1 0.0027
408 0.3387 0.3387 JUN 0.0027
409 0.3387 0.3387 CTNNB1 0.0027
410 0.3387 0.3387 PIK3R1 0.0027
411 0.3387 0.3387 PRKN 0.0027
412 0.3405 0.3405 CYFIP2,PIK3R1,VAV3,CHRM5 0.0191
413 0.3418 0.3418 PIK3R1,JUN 0.0079
414 0.3447 0.3447 PIK3R1,JUN,UQCRFS1 0.0135
415 0.3468 0.3468 PIK3R1,CTNNB1 0.008
416 0.3478 0.3478 BHLHE41 0.0028
417 0.3478 0.3478 CENPA 0.0028
418 0.3478 0.3478 JUN 0.0028
419 0.3478 0.3478 PIK3R1 0.0028
420 0.3478 0.3478 GALNT2 0.0028
表7.d2
   基因集 基因集中之數目 來自清單
421 p38 mapk信號傳導路徑(B) 31 1
422 藉由gpcr進行egf受體反式激活在心肥大中之作用(B) 31 1
423 轉運所需的核內體分選複合物(ESCRT) (R) 31 1
424 EPHA正向信號傳導(N) 31 1
425 擴張型心肌症(K) 90 2
426 吞噬細胞中之ROS、RNS生產(R) 32 1
427 src激酶之√ü抑制蛋白依賴性募集在gpcr信號傳導中之作用(B) 32 1
428 DAG及IP3信號傳導(R) 32 1
429 鐸樣受體路徑(B) 32 1
430 由MAPK路徑介導之Trk受體信號傳導(N) 33 1
431 氧化氮在心臟中之作用(B) 33 1
432 FAS信號傳導路徑(P) 33 1
433 EPO信號傳導路徑(N) 33 1
434 壽命調節路徑(K) 94 2
435 IL8及CXCR2介導之信號傳導事件(N) 34 1
436 類固醇激素受體(SHR)之Hsp90伴隨蛋白週期(R) 34 1
437 囊泡轉運中之SNARE相互作用(K) 34 1
438 藉由NGF進行信號傳導(R) 159 3
439 a6b1及a6b4整合素信號傳導(N) 35 1
440 由PI3K介導之IL2信號傳導事件(N) 35 1
441 CXCR3介導之信號傳導事件(N) 35 1
442 經由il1r進行信號轉導(B) 35 1
443 由Akt介導之I類PI3K信號傳導事件(N) 35 1
444 由TCPTP介導之信號傳導事件(N) 35 1
445 造血細胞譜系(K) 97 2
446 Ras信號傳導路徑(K) 229 4
447 孕酮介導之卵母細胞成熟(K) 98 2
448 由PI3K及PLC-γ介導之Trk受體信號傳導(N) 36 1
449 過氧化體增殖物經由ppara調節基因的機制(B) 36 1
450 藉由碳水化合物及camp進行chrebp調節(B) 36 1
451 RET信號傳導(R) 36 1
452 磷脂醯環己六醇信號傳導系統(K) 99 2
453 內質網中之蛋白質處理(K) 165 3
454 AP1家庭成員Fra1及Fra2之驗證轉錄目標(N) 37 1
455 IL23介導之信號傳導事件(N) 37 1
456 rac1細胞運動信號傳導路徑(B) 37 1
457 ErbB2/ErbB3信號傳導事件(N) 37 1
458 逆行內源性類大麻酚信號傳導(K) 101 2
459 TNF信號傳導(R) 38 1
460 由II類HDAC介導之信號傳導事件(N) 38 1
461 EPHB正向信號傳導(N) 38 1
462 HIF-1信號傳導路徑(K) 103 2
463 纖維蛋白凝塊之形成(凝固級聯) (R) 39 1
464 鐵死亡(K) 40 1
465 色胺酸代謝(K) 40 1
466 Aurora B信號傳導(N) 40 1
467 預NOTCH表現及處理(R) 40 1
468 藉由FGFR3進行信號傳導(R) 40 1
469 FOXA2及FOXA3轉錄因子網絡(N) 40 1
470 FOXM1轉錄因子網絡(N) 40 1
471 I類PI3K信號傳導事件(N) 40 1
472 尼古丁成癮(K) 40 1
473 藉由SCF-KIT進行信號傳導(R) 41 1
474 藉由camp依賴性蛋白激酶活化csk抑制經由t細胞受體之信號傳導(B) 41 1
475 藉由FGFR4進行信號傳導(R) 41 1
476 BMP受體信號傳導(N) 41 1
477 脂肪消化及吸收(K) 41 1
478 藉由EGFR進行信號傳導(R) 41 1
479 同源重組(K) 41 1
480 A型流感(K) 175 3
481 心肌導電(R) 107 2
482 轉譯後蛋白質磷酸化(R) 107 2
483 FOXA1轉錄因子網絡(N) 42 1
484 質膜雌激素受體信號傳導(N) 42 1
485 藉由ERBB2進行信號傳導(R) 43 1
486 PAR1介導之凝血酶信號傳導事件(N) 43 1
487 藉由ERBB4進行信號傳導(R) 43 1
488 β3整合素細胞表面相互作用(N) 43 1
489 Cilium組裝(R) 179 3
490 癌症中之轉錄異常調節(K) 180 3
491 參與巨核細胞發育及血小板生產之因子(R) 111 2
492 p53路徑(P) 44 1
493 抗利尿素調節的水再吸收(K) 44 1
494 β-連環蛋白非依賴性WNT信號傳導(R) 112 2
495 血清素激導性突觸(K) 113 2
496 反高爾基體網絡囊泡出芽(R) 45 1
497 ρA信號傳導路徑(N) 45 1
498 醚脂質代謝(K) 45 1
499 δNp63同功型之驗證轉錄目標(N) 45 1
500 突觸後分化中之聚集蛋白(B) 45 1
501 單純疱疹感染(K) 185 3
502 ρA活性之調節(N) 46 1
503 介白素-10信號傳導(R) 47 1
504 澱粉樣纖維形成(R) 47 1
505 鞘脂代謝(K) 47 1
506 角質細胞分化(B) 47 1
507 凋亡執行期(R) 47 1
508 弓蟲病(K) 118 2
509 網格蛋白介導之內吞作用(R) 118 2
510 類泛素化(R) 118 2
511 腦醯胺信號傳導路徑(N) 48 1
512 脂肪酸代謝(K) 48 1
513 纈胺酸、白胺酸及異白胺酸分解(K) 48 1
514 I類MHC介導之抗原處理及代表(R) 191 3
515 軸突引導因子-1信號傳導(R) 49 1
516 藉由FGFR1進行信號傳導(R) 49 1
517 雄激素受體活性之調節(N) 49 1
518 瘧疾(K) 49 1
519 用於IgA生產之腸道免疫網絡(K) 49 1
520 藉由類胰島素生長因子結合蛋白(IGFBP)進行類胰島素生長因子(IGF)轉運及攝取之調節(R) 120 2
521 神經營養蛋白信號傳導路徑(K) 121 2
522 血管平滑肌收縮(K) 121 2
523 軸突蛋白及神經配蛋白(R) 50 1
表7.e1
   P值 FDR 節點 基因集中蛋白質之比率
421 0.3478 0.3478 MEF2C 0.0028
422 0.3478 0.3478 JUN 0.0028
423 0.3478 0.3478 CHMP5 0.0028
424 0.3478 0.3478 VAV3 0.0028
425 0.3517 0.3517 ADCY2,CACNG2 0.008
426 0.3567 0.3567 ATP6V1G1 0.0029
427 0.3567 0.3567 ADRB2 0.0029
428 0.3567 0.3567 ADCY2 0.0029
429 0.3567 0.3567 JUN 0.0029
430 0.3655 0.3655 MEF2C 0.0029
431 0.3655 0.3655 PIK3R1 0.0029
432 0.3655 0.3655 JUN 0.0029
433 0.3655 0.3655 PIK3R1 0.0029
434 0.3715 0.3715 PIK3R1,ADCY2 0.0084
435 0.3742 0.3742 ELMO1 0.003
436 0.3742 0.3742 DYNC1I1 0.003
437 0.3742 0.3742 SNAP29 0.003
438 0.3746 0.3746 MEF2C,PIK3R1,VAV3 0.0142
439 0.3828 0.3828 PIK3R1 0.0031
440 0.3828 0.3828 PIK3R1 0.0031
441 0.3828 0.3828 RICTOR 0.0031
442 0.3828 0.3828 JUN 0.0031
443 0.3828 0.3828 RICTOR 0.0031
444 0.3828 0.3828 PTPN2 0.0031
445 0.3861 0.3861 IL4R,CSF2RA 0.0087
446 0.3872 0.3872 PIK3R1,GRIN2A,RAPGEF5,PLA2G4A 0.0205
447 0.391 0.391 PIK3R1,ADCY2 0.0088
448 0.3913 0.3913 PIK3R1 0.0032
449 0.3913 0.3913 JUN 0.0032
450 0.3913 0.3913 ADRB2 0.0032
451 0.3913 0.3913 PIK3R1 0.0032
452 0.3958 0.3958 PIK3R1,PI4KA 0.0088
453 0.3969 0.3969 CAPN2,BAG1,PPP1R15A 0.0147
454 0.3996 0.3996 JUN 0.0033
455 0.3996 0.3996 PIK3R1 0.0033
456 0.3996 0.3996 PIK3R1 0.0033
457 0.3996 0.3996 JUN 0.0033
458 0.4054 0.4054 ADCY2,PTGS2 0.009
459 0.4079 0.4079 SMPD3 0.0034
460 0.4079 0.4079 MEF2C 0.0034
461 0.4079 0.4079 PIK3R1 0.0034
462 0.415 0.415 PIK3R1,IFNGR1 0.0092
463 0.416 0.416 SERPIND1 0.0035
464 0.424 0.424 SLC39A14 0.0036
465 0.424 0.424 CYP1B1 0.0036
466 0.424 0.424 CENPA 0.0036
467 0.424 0.424 JUN 0.0036
468 0.424 0.424 PIK3R1 0.0036
469 0.424 0.424 SLC2A2 0.0036
470 0.424 0.424 CENPA 0.0036
471 0.424 0.424 SGK1 0.0036
472 0.424 0.424 GRIN2A 0.0036
473 0.4319 0.4319 PIK3R1 0.0037
474 0.4319 0.4319 ADRB2 0.0037
475 0.4319 0.4319 PIK3R1 0.0037
476 0.4319 0.4319 PPP1R15A 0.0037
477 0.4319 0.4319 DGAT2 0.0037
478 0.4319 0.4319 PIK3R1 0.0037
479 0.4319 0.4319 RAD51B 0.0037
480 0.4335 0.4335 PIK3R1,JUN,IFNGR1 0.0156
481 0.4339 0.4339 RYR3,CACNG2 0.0096
482 0.4339 0.4339 SERPIND1,NUCB1 0.0096
483 0.4397 0.4397 JUN 0.0038
484 0.4397 0.4397 PIK3R1 0.0038
485 0.4474 0.4474 PIK3R1 0.0038
486 0.4474 0.4474 PIK3R1 0.0038
487 0.4474 0.4474 PIK3R1 0.0038
488 0.4474 0.4474 COL4A1 0.0038
489 0.4479 0.4479 CC2D2A,IFT27,CLASP1 0.016
490 0.4515 0.4515 MEF2C,ARNT2,MEIS1 0.0161
491 0.4524 0.4524 RAD51B,DOCK11 0.0099
492 0.455 0.455 GADD45G 0.0039
493 0.455 0.455 DYNC1I1 0.0039
494 0.457 0.457 FZD3,CTNNB1 0.01
495 0.4615 0.4615 PTGS2,PLA2G4A 0.0101
496 0.4624 0.4624 DNAJC6 0.004
497 0.4624 0.4624 JUN 0.004
498 0.4624 0.4624 PLA2G4A 0.004
499 0.4624 0.4624 FBXW7 0.004
500 0.4624 0.4624 JUN 0.004
501 0.4693 0.4693 JUN,IFNGR1,TRAF5 0.0165
502 0.4698 0.4698 VAV3 0.0041
503 0.4771 0.4771 PTGS2 0.0042
504 0.4771 0.4771 PRKN 0.0042
505 0.4771 0.4771 SMPD3 0.0042
506 0.4771 0.4771 JUN 0.0042
507 0.4771 0.4771 CTNNB1 0.0042
508 0.484 0.484 PIK3R1,IFNGR1 0.0105
509 0.484 0.484 ADRB2,DNAJC6 0.0105
510 0.484 0.484 NSMCE1,SEH1L 0.0105
511 0.4843 0.4843 SMPD3 0.0043
512 0.4843 0.4843 HACD3 0.0043
513 0.4843 0.4843 BCAT2 0.0043
514 0.4903 0.4903 NEDD4L,FBXL5,FBXW7 0.0171
515 0.4914 0.4914 ROBO1 0.0044
516 0.4914 0.4914 PIK3R1 0.0044
517 0.4914 0.4914 JUN 0.0044
518 0.4914 0.4914 KLRK1 0.0044
519 0.4914 0.4914 TNFRSF17 0.0044
520 0.4928 0.4928 SERPIND1,NUCB1 0.0107
521 0.4972 0.4972 PIK3R1,JUN 0.0108
522 0.4972 0.4972 ADCY2,PLA2G4A 0.0108
523 0.4983 0.4983 GRIN2A 0.0045
表7.e2
編號 群組 探針 基因座 Probe_Count_Total
1 A ORF130_1_181484002_181486199_181499646_181512034_RF N/A N/A
2 A ORF121_5_68461134_68466125_68476885_68484945_RR N/A N/A
3 A ORF197_13_110131405_110134324_110146402_110150942_FR N/A N/A
4 A ORF138_15_65573794_65596385_65611369_65614380_RF N/A N/A
5 A ORF11_10_76403646_76410014_76489182_76492128_RR N/A N/A
6 A ORF14_10_80184350_80188816_80268946_80271961_RF N/A N/A
7 A ORF133_1_103373638_103377704_103450404_103453588_RF N/A N/A
8 A ORF16_6_154154477_154163186_154217494_154220454_RR N/A N/A
9 A ORF138_2_87446096_87451261_87563076_87564920_RF N/A N/A
10 A ORF198_9_28270698_28275294_28314155_28333777_RF N/A N/A
11 A ORF151_12_30089465_30094558_30144610_30146709_RR N/A N/A
12 A ORF175_19_29325557_29328725_29376361_29378170_RR N/A N/A
13 B ORF198_6_47004707_47009616_47060758_47069708_RF N/A N/A
14 B ORF161_15_76059101_76063008_76127902_76129439_FR N/A N/A
15 B ORF18_9_94753448_94757906_94818790_94822742_FF N/A N/A
16 B ORF19_4_37859966_37862832_37889307_37892348_FR N/A N/A
17 B ORF115_8_41556026_41557719_41620524_41625614_RR N/A N/A
18 B ORF18_5_53020744_53026231_53104495_53107169_FR N/A N/A
19 B ORF13_3_10213510_10218995_10289864_10293604_RF N/A N/A
20 B ORF16_2_104860979_104864045_104945453_104950314_RR N/A N/A
21 B ORF19_11_49172113_49176734_49212875_49219818_RF N/A N/A
22 B ORF138_5_14296086_14298950_14351872_14353515_RR N/A N/A
23 B ORF191_5_14296086_14298950_14364873_14369388_RR N/A N/A
24 B ORF11_4_151874649_151880301_151939544_151951330_FF N/A N/A
25 B ORF170_2_42093750_42101196_42135668_42138124_RR N/A N/A
26 B ORF186_1_98703842_98709502_98720841_98724148_RF N/A N/A
27 B ORF197_9_28314155_28333777_28371887_28374860_FF N/A N/A
28 B ORF121_2_169230822_169232519_169312990_169323273_RF N/A N/A
29 B ORF196_18_61281289_61284639_61298113_61310562_RR N/A N/A
30 B ORF187_2_68359452_68365969_68410496_68416848_FF N/A N/A
31 B ORF147_1_229796281_229797522_229849427_229855718_RF N/A N/A
32 B ORF180_5_14296086_14298950_14331605_14334109_RR N/A N/A
33 B ORF18_4_151874649_151880301_152011202_152016397_FR N/A N/A
34 B ORF196_8_101906298_101909241_101944457_101954546_FF N/A N/A
35 B ORF158_2_71849462_71852445_71889643_71894860_FF N/A N/A
36 B ORF1_2_122384211_122392026_122423621_122431761_FR N/A N/A
37 B ORF18_14_99815362_99818414_99884900_99886697_FF N/A N/A
38 B ORF143_5_14296086_14298950_14319858_14323303_RR N/A N/A
39 B ORF168_13_50679892_50686027_50716471_50721185_RR N/A N/A
40 B ORF14_3_84107388_84117146_84158429_84159782_FF N/A N/A
41 B ORF103_1_152785124_152809368_152824653_152831895_FR N/A N/A
42 B ORF176_5_14296086_14298950_14334109_14335762_RR N/A N/A
43 B ORF14_10_23011505_23013473_23046337_23050583_FR N/A N/A
44 B ORF106_2_122420370_122422532_122487405_122491476_FF N/A N/A
45 B ORF199_1_98683897_98688922_98703842_98709502_FF N/A N/A
46 B ORF184_1_116953472_116956520_117001584_117004481_FR N/A N/A
47 B ORF147_2_104614222_104616408_104659695_104660711_RR N/A N/A
48 B ORF14_6_152926115_152930237_153001408_153002544_RR N/A N/A
49 B ORF158_2_38148629_38155476_38173151_38175882_FF N/A N/A
50 B ORF123_10_104238473_104242119_104302206_104311403_FF N/A N/A
51 B ORF16_11_86195747_86200973_86253845_86255008_RF N/A N/A
表8.1a
編號 群組 Probe_Count_Sig HyperG_Stats FDR_HyperG Percent_Sig logFC AveExpr
1 A N/A N/A N/A N/A -0.902920687 -0.902920687
2 A N/A N/A N/A N/A -0.889155137 -0.889155137
3 A N/A N/A N/A N/A -0.86271955 -0.86271955
4 A N/A N/A N/A N/A -0.848473602 -0.848473602
5 A N/A N/A N/A N/A -0.835298815 -0.835298815
6 A N/A N/A N/A N/A -0.782417152 -0.782417152
7 A N/A N/A N/A N/A -0.778372431 -0.778372431
8 A N/A N/A N/A N/A -0.745666862 -0.745666862
9 A N/A N/A N/A N/A -0.735464874 -0.735464874
10 A N/A N/A N/A N/A -0.727431725 -0.727431725
11 A N/A N/A N/A N/A -0.716810383 -0.716810383
12 A N/A N/A N/A N/A -0.715276704 -0.715276704
13 B N/A N/A N/A N/A -0.687883693 -0.687883693
14 B N/A N/A N/A N/A -0.681233027 -0.681233027
15 B N/A N/A N/A N/A -0.678970006 -0.678970006
16 B N/A N/A N/A N/A -0.678791947 -0.678791947
17 B N/A N/A N/A N/A -0.665154204 -0.665154204
18 B N/A N/A N/A N/A -0.663925239 -0.663925239
19 B N/A N/A N/A N/A -0.656008231 -0.656008231
20 B N/A N/A N/A N/A -0.648923367 -0.648923367
21 B N/A N/A N/A N/A -0.648598444 -0.648598444
22 B N/A N/A N/A N/A -0.643334074 -0.643334074
23 B N/A N/A N/A N/A -0.639512041 -0.639512041
24 B N/A N/A N/A N/A -0.637859012 -0.637859012
25 B N/A N/A N/A N/A -0.632921191 -0.632921191
26 B N/A N/A N/A N/A -0.62980323 -0.62980323
27 B N/A N/A N/A N/A -0.627429902 -0.627429902
28 B N/A N/A N/A N/A -0.626569707 -0.626569707
29 B N/A N/A N/A N/A -0.624898453 -0.624898453
30 B N/A N/A N/A N/A -0.624119123 -0.624119123
31 B N/A N/A N/A N/A -0.621507065 -0.621507065
32 B N/A N/A N/A N/A -0.621446146 -0.621446146
33 B N/A N/A N/A N/A -0.618124191 -0.618124191
34 B N/A N/A N/A N/A -0.617660574 -0.617660574
35 B N/A N/A N/A N/A -0.617154289 -0.617154289
36 B N/A N/A N/A N/A -0.613623079 -0.613623079
37 B N/A N/A N/A N/A -0.612984927 -0.612984927
38 B N/A N/A N/A N/A -0.612332048 -0.612332048
39 B N/A N/A N/A N/A -0.6089308 -0.6089308
40 B N/A N/A N/A N/A -0.605636682 -0.605636682
41 B N/A N/A N/A N/A -0.604074502 -0.604074502
42 B N/A N/A N/A N/A -0.603384069 -0.603384069
43 B N/A N/A N/A N/A -0.603375187 -0.603375187
44 B N/A N/A N/A N/A -0.601854078 -0.601854078
45 B N/A N/A N/A N/A -0.597131608 -0.597131608
46 B N/A N/A N/A N/A -0.595769876 -0.595769876
47 B N/A N/A N/A N/A -0.593494634 -0.593494634
48 B N/A N/A N/A N/A -0.590844113 -0.590844113
49 B N/A N/A N/A N/A -0.589565118 -0.589565118
50 B N/A N/A N/A N/A -0.587157203 -0.587157203
51 B N/A N/A N/A N/A -0.587033847 -0.587033847
表8.1b
編號 群組 t P值 adj.P.Val B FC
1 A -9.38731335 0.000000715 0.0000326 6.348570481 0.534802944
2 A -4.961829562 0.000331268 0.001966927 0.021524681 0.539930217
3 A -6.034736926 0.0000593 0.000574116 1.796815874 0.549914964
4 A -13.20468402 0.0000000168 0.00000376 10.11545576 0.555372019
5 A -6.8024921 0.0000191 0.000267386 2.96804814 0.560466942
6 A -6.609249636 0.0000252 0.000320879 2.681009587 0.581391888
7 A -6.081742554 0.0000552 0.000545563 1.870907921 0.583024158
8 A -5.056523908 0.000282775 0.001751743 0.184531457 0.596392135
9 A -5.640110527 0.000109603 0.000882937 1.162457071 0.600624457
10 A -6.076430002 0.0000557 0.000548855 1.862549761 0.603978155
11 A -4.824893047 0.000417375 0.002330466 -0.216233165 0.608441143
12 A -3.308889367 0.006249188 0.01792273 -2.96908133 0.609088299
13 B -5.047203264 0.000287199 0.001773127 0.168538832 0.620763789
14 B -5.981769231 0.0000643 0.000608428 1.712951136 0.623632048
15 B -5.298211018 0.000189869 0.001308735 0.595183735 0.624611049
16 B -5.775445295 0.0000886 0.000759746 1.382486511 0.624688144
17 B -6.870629659 0.0000173 0.000250977 3.068032199 0.630621296
18 B -5.17542456 0.000232218 0.001516237 0.387535885 0.631158722
19 B -19.24384862 0.000000000224 0.000000504 14.21218591 0.634631822
20 B -6.714680693 0.0000217 0.000290585 2.838254337 0.637756071
21 B -3.385076424 0.005428065 0.016033727 -2.827972579 0.637899723
22 B -11.46063564 0.0000000818 0.00000877 8.54339294 0.64023166
23 B -11.34612693 0.0000000914 0.00000932 8.432106811 0.64193003
24 B -7.067484022 0.0000132 0.00020839 3.353340227 0.64266597
25 B -5.40483293 0.000159687 0.001154243 0.77382722 0.644869351
26 B -6.599617102 0.0000256 0.000324001 2.666566302 0.646264554
27 B -6.233575612 0.0000439 0.000464641 2.108096562 0.647328576
28 B -5.605724746 0.000115744 0.000917397 1.106141508 0.647714656
29 B -9.05963493 0.00000104 0.0000411 5.963390203 0.648465419
30 B -3.323834796 0.006078736 0.017528448 -2.94140664 0.648815809
31 B -8.313648073 0.00000256 0.0000720 5.042225938 0.64999158
32 B -12.9536673 0.0000000209 0.00000421 9.902524499 0.650019027
33 B -4.502206964 0.000726605 0.00351567 -0.785529316 0.651517488
34 B -9.529608459 0.000000609 0.0000293 6.512318007 0.65172689
35 B -11.11023611 0.000000115 0.0000106 8.199449941 0.651955641
36 B -9.755373492 0.000000474 0.0000251 6.76787139 0.653553353
37 B -4.777223426 0.000452603 0.002475169 -0.299551671 0.653842506
38 B -9.483635178 0.000000641 0.0000302 6.45964271 0.654138463
39 B -8.685447734 0.00000162 0.0000543 5.509240867 0.655682456
40 B -6.703813142 0.0000220 0.000293554 2.822117105 0.657181292
41 B -6.976761828 0.0000149 0.000226924 3.222506325 0.657893288
42 B -11.37023574 0.0000000893 0.00000920 8.45562596 0.658208212
43 B -9.529496253 0.000000609 0.0000293 6.512189708 0.658212264
44 B -12.35548287 0.0000000355 0.00000557 9.377666266 0.658906618
45 B -5.239946908 0.000208849 0.00140058 0.496906124 0.661066995
46 B -4.261340534 0.001108625 0.004818807 -1.218000824 0.661691258
47 B -10.20742817 0.000000291 0.0000186 7.264427169 0.66273562
48 B -7.421354391 0.00000811 0.000151023 3.853159105 0.663954317
49 B -4.819712462 0.00042106 0.002345452 -0.225274349 0.664543195
50 B -5.492987202 0.000138558 0.001043057 0.920343575 0.66565327
51 B -6.344949678 0.0000372 0.000414647 2.280011436 0.665710188
表8.1c
編號 群組 FC_1 LS 偵測到之環
1 A -1.869847597 -1 重度自閉症
2 A -1.852091195 -1 重度自閉症
3 A -1.818462972 -1 重度自閉症
4 A -1.800594855 -1 重度自閉症
5 A -1.784226554 -1 重度自閉症
6 A -1.720010238 -1 重度自閉症
7 A -1.715194793 -1 重度自閉症
8 A -1.67674914 -1 重度自閉症
9 A -1.664933868 -1 重度自閉症
10 A -1.655689021 -1 重度自閉症
11 A -1.643544345 -1 重度自閉症
12 A -1.641798079 -1 重度自閉症
13 B -1.610918708 -1 重度自閉症
14 B -1.603509639 -1 重度自閉症
15 B -1.600996335 -1 重度自閉症
16 B -1.600798751 -1 重度自閉症
17 B -1.585737757 -1 重度自閉症
18 B -1.584387517 -1 重度自閉症
19 B -1.575716762 -1 重度自閉症
20 B -1.567997618 -1 重度自閉症
21 B -1.567644513 -1 重度自閉症
22 B -1.561934629 -1 重度自閉症
23 B -1.557802179 -1 重度自閉症
24 B -1.556018283 -1 重度自閉症
25 B -1.550701701 -1 重度自閉症
26 B -1.547353934 -1 重度自閉症
27 B -1.544810528 -1 重度自閉症
28 B -1.543889722 -1 重度自閉症
29 B -1.542102277 -1 重度自閉症
30 B -1.541269473 -1 重度自閉症
31 B -1.538481467 -1 重度自閉症
32 B -1.538416505 -1 重度自閉症
33 B -1.534878217 -1 重度自閉症
34 B -1.534385056 -1 重度自閉症
35 B -1.533846688 -1 重度自閉症
36 B -1.530096962 -1 重度自閉症
37 B -1.529420298 -1 重度自閉症
38 B -1.528728329 -1 重度自閉症
39 B -1.525128498 -1 重度自閉症
40 B -1.521650132 -1 重度自閉症
41 B -1.520003348 -1 重度自閉症
42 B -1.519276092 -1 重度自閉症
43 B -1.519266738 -1 重度自閉症
44 B -1.51766574 -1 重度自閉症
45 B -1.512705986 -1 重度自閉症
46 B -1.511278845 -1 重度自閉症
47 B -1.508897319 -1 重度自閉症
48 B -1.506127717 -1 重度自閉症
49 B -1.504793078 -1 重度自閉症
50 B -1.502283614 -1 重度自閉症
51 B -1.502155169 -1 重度自閉症
表8.1d
   探針序列 探針位置
編號 群組 60 mer Chr
1 A CATTTGCAGATTTGTTAATAGTATAAAATCGATTGGCCATATCCTTTCTTGCCCACCATA 1
2 A TATTTTTCTTTATCTGAATTTATAACTTTCGATTTTTTTCATGCTCCTCTCCAATTCTGT 5
3 A TTTAAACTGATAAGAACAGATATTACCCTCGAAATGTAGTAAGTAAAACCATAAAACTTT 13
4 A AACAATAAATCCCTAATATCATCAAATATCGATTTTAGTATGACAACTAAGAACATAAAA 15
5 A ACTCTTCAAAATTATAATTATCAACAATTCGATTTTGTTACTTGTTATTGGTCTTTTCAG 10
6 A GGAAAGTATAAAATTCTGAATTTTCATGTCGACTTATGATTTTTCAACTTTATGATGGTG 10
7 A AGTCCTTATTGAGTGATCTTTATATTACTCGAAAAACTCTTATCAGGATAAGAATAATGG 1
8 A TTATATTGGAAATCTGTTTCAACAATAATCGATTCAGCATAAAATAAATGCAAATGAAAG 6
9 A ATATTATGTTCTAGAAAAGGTAGAATTATCGAGATTTACTCATAGGCACTGAGTTTCAAA 2
10 A AAAGTCATACAACTACTATGTAAGATATTCGAATTTGTGCTTGTTGGGAAAATAGTAATT 9
11 A ATGGTAAGTTTTGGGAATTCAAAGAACCTCGATTCTCAGCTATATCCTTAATACTGGAAG 12
12 A CTTAAAGCTGTCTAAATTTTATCTTAGTTCGAGGCCCTTTCAGGACTCTTTTCCTGGGGA 19
13 B TTGGAAAAGGTAAATTGTGTTTTGTAAATCGAGTGATTTTTAGTTCTTCCAGACATAAAA 6
14 B TAAAACTGGGATATTTGTTTTTCCTTGATCGAACACTCCAGACATACTAAATTAGAAATT 15
15 B GATTACATAGAAATAGCCAATGGATTTATCGATAAACAGTTCCTATCATCAGCTATGGAG 9
16 B CCTACCAGAACTCTTAAATCTATAATATTCGACTAACTCCTCCGTAAAGAATAGCTACCA 4
17 B TAAAGTTTTGGAAGAAAATATTGGAAACTCGATATTTCTTAAAGCATGTCTACCTTCCAT 8
18 B CTCCTTTGATGTAGTCATCAATGCCTTTTCGAAATTCCAAAAAACTGCATTTTTAGAACC 5
19 B TTTTGTCCTAGTTGTAGCTTTTATAATTTCGAAAGATTCTTCCAGGCAGAGTTGCAGATT 3
20 B GTTAAAATTATTTAAAATATTACACTTATCGACAGAAAAATCAAACTTCTGGTCATGGCT 2
21 B ATGTGTTTTTCAAATTTTATCAAAAAGCTCGAGTCTTTTGTTTTTGTCAATAGTATTATT 11
22 B AACCCCTCTGAGCAAATCTCCCACTGCCTCGACTTAACTGGAGGCTTGGTCCTTTCCGAG 5
23 B AACCCCTCTGAGCAAATCTCCCACTGCCTCGACTTCCCGGAAATTCTGACCTGTAGCATT 5
24 B TTTAAAATAGTGAATTTAAATTCATCCATCGACATTTCAAAAAAAAACCAGATCTGTCTT 4
25 B AAATCCCTTCAATGGCTTTTTTTTTTTTTCGAAGCTTACTCTGAGTACCACCTCCTTCAG 2
26 B TTGATGAGAGTTGATTCATAAGTTAATATCGAAGTTAGTGGTTAGACAAAATTTTGCTCT 1
27 B AAAGTCATACAACTACTATGTAAGATATTCGAGGTGGGTCAATTTGTCAAATTAAAAGAA 9
28 B TGTCAAATTCACCTTTTCAGTAGTAACTTCGACCCAATAAAATATCTCTAGGATGAGATA 2
29 B TATTCTGTTGAATTGTTTTGGTTTTCTTTCGAAAGACTCCAAGACAGGAACAAGCGTGGC 18
30 B ATTCTTAGTAAATTTGCATAATGTGGCATCGATAAAATTCTTCTCCGCCTTACTCACTCT 2
31 B AACCGGTTTTGTCACAAACATTGAAAAATCGACGTTTATTTTATACAAACAATAAAGACA 1
32 B AACCCCTCTGAGCAAATCTCCCACTGCCTCGAACCTCATGTTTAGGTGGTGGAAGCGAGT 5
33 B TTTAAAATAGTGAATTTAAATTCATCCATCGAGAAATAAGGTACAAAAAGTAGAAGAGAC 4
34 B AATTACAAATAAAAGCCAATTCAATTTTTCGATTGAAAGAGGATGACGATTGTTTCCCTC 8
35 B TTATTTAATCATTAATTTCCTCCTCTCGTCGAAGGTACAAATTGTTTTCAAATGGAAAGA 2
36 B CTGCCTTTAGGGATAACATTTTACTGGTTCGACAAGTTAATCTTCCTAACAAGAATCACT 2
37 B ATATTTAATGTCCTATATCTGCAGATATTCGACACGTGGTGACATGTGTAAGAAGTCCTG 14
38 B AACCCCTCTGAGCAAATCTCCCACTGCCTCGAGGTTAATTTTTTCCCCTCTTAATAAGCG 5
39 B ACTAGTTAACATTTCGTCTAAAATTTTATCGAGGAAGGCTAATGTTTTTTGATCTCTAAT 13
40 B TCTTCATAGCTAAATGTATTACTAAGCTTCGAAAAAATTATTTAATTTGTGCTAACGTTA 3
41 B CTATAGAAATTAAAATAATATTAAGAGTTCGAGTGATTCTTTAAAAATTGAACATTTCCA 1
42 B AACCCCTCTGAGCAAATCTCCCACTGCCTCGATTTCCTCGCCTGTGAAATGGGAAATCAG 5
43 B TATTTAGCTATAGTTTTTTCTCACTTTATCGAGTGATAGTCCAATTAGTTTATTTATAGG 10
44 B TTGGAATTCATAGCAATTGCTGCTGCATTCGAAATCGGCAGAGTTTGTTCATTCAATTAG 2
45 B TGTGCATCTTTTTTCTTTTTTTCTTTTTTCGAGTGAGTTGAGTTAAAATAATTCCGTAGG 1
46 B TCTCTTCAGTCATTATTTAAACTACTTATCGATATCTGTTTACTTAACCACAAAGATAAC 1
47 B AAAACTCAGGCTTTGCCACTGAGAGACCTCGAGGCCTCCACCCCTGCCCCGGAGAGAAAG 2
48 B TGCTTTTGAACGGCTTTTAAAATAATTCTCGAGAGCTCTCATATGATTATTTGGGCTCAA 6
49 B TCATAAAATAATAATTAACAAACATACATCGATGCCAAGTCTTTCTTCTGGTTTCTTTAT 2
50 B AGACTTCATTTTCAAGCTTCAAATATTTTCGATTTTTAAAGATTTCCCCCAAGTGACTGA 10
51 B ATGAAATATAAGTTTAAAAGATTGGAAATCGACAATGGGTTATTCAGGAATTTAAACTTT 11
表8.1e
      探針位置 4 kb序列位置
編號 群組 起點 1 終點 1 起點 2 終點 2 Chr 起點 1  
1 A 181484004 181484033 181512003 181512032 1 181484004  
2 A 68461136 68461165 68476887 68476916 5 68461136  
3 A 110134293 110134322 110146404 110146433 13 110130323  
4 A 65573796 65573825 65614349 65614378 15 65573796  
5 A 76403648 76403677 76489184 76489213 10 76403648  
6 A 80184352 80184381 80271930 80271959 10 80184352  
7 A 103373640 103373669 103453557 103453586 1 103373640  
8 A 154154479 154154508 154217496 154217525 6 154154479  
9 A 87446098 87446127 87564889 87564918 2 87446098  
10 A 28270700 28270729 28333746 28333775 9 28270700  
11 A 30089467 30089496 30144612 30144641 12 30089467  
12 A 29325559 29325588 29376363 29376392 19 29325559  
13 B 47004709 47004738 47069677 47069706 6 47004709  
14 B 76062977 76063006 76127904 76127933 15 76059007  
15 B 94757875 94757904 94822711 94822740 9 94753905  
16 B 37862801 37862830 37889309 37889338 4 37858831  
17 B 41556028 41556057 41620526 41620555 8 41556028  
18 B 53026200 53026229 53104497 53104526 5 53022230  
19 B 10213512 10213541 10293573 10293602 3 10213512  
20 B 104860981 104861010 104945455 104945484 2 104860981  
21 B 49172115 49172144 49219787 49219816 11 49172115  
22 B 14296088 14296117 14351874 14351903 5 14296088  
23 B 14296088 14296117 14364875 14364904 5 14296088  
24 B 151880270 151880299 151951299 151951328 4 151876300  
25 B 42093752 42093781 42135670 42135699 2 42093752  
26 B 98703844 98703873 98724117 98724146 1 98703844  
27 B 28333746 28333775 28374829 28374858 9 28329776  
28 B 169230824 169230853 169323242 169323271 2 169230824  
29 B 61281291 61281320 61298115 61298144 18 61281291  
30 B 68365938 68365967 68416817 68416846 2 68361968  
31 B 229796283 229796312 229855687 229855716 1 229796283  
32 B 14296088 14296117 14331607 14331636 5 14296088  
33 B 151880270 151880299 152011204 152011233 4 151876300  
34 B 101909210 101909239 101954515 101954544 8 101905240  
35 B 71852414 71852443 71894829 71894858 2 71848444  
36 B 122391995 122392024 122423623 122423652 2 122388025  
37 B 99818383 99818412 99886666 99886695 14 99814413  
38 B 14296088 14296117 14319860 14319889 5 14296088  
39 B 50679894 50679923 50716473 50716502 13 50679894  
40 B 84117115 84117144 84159751 84159780 3 84113145  
41 B 152809337 152809366 152824655 152824684 1 152805367  
42 B 14296088 14296117 14334111 14334140 5 14296088  
43 B 23013442 23013471 23046339 23046368 10 23009472  
44 B 122422501 122422530 122491445 122491474 2 122418531  
45 B 98688891 98688920 98709471 98709500 1 98684921  
46 B 116956489 116956518 117001586 117001615 1 116952519  
47 B 104614224 104614253 104659697 104659726 2 104614224  
48 B 152926117 152926146 153001410 153001439 6 152926117  
49 B 38155445 38155474 38175851 38175880 2 38151475  
50 B 104242088 104242117 104311372 104311401 10 104238118  
51 B 86195749 86195778 86254977 86255006 11 86195749  
表8.1f
      4 kb 序列位置
編號 群組 終點 1 起 點 2 終點 2 探針
1 A 181488003 181508033 181512032 ORF130_1_181484002_181486199_181499646_181512034_RF
2 A 68465135 68476887 68480886 ORF121_5_68461134_68466125_68476885_68484945_RR
3 A 110134322 110146404 110150403 ORF197_13_110131405_110134324_110146402_110150942_FR
4 A 65577795 65610379 65614378 ORF138_15_65573794_65596385_65611369_65614380_RF
5 A 76407647 76489184 76493183 ORF11_10_76403646_76410014_76489182_76492128_RR
6 A 80188351 80267960 80271959 ORF14_10_80184350_80188816_80268946_80271961_RF
7 A 103377639 103449587 103453586 ORF133_1_103373638_103377704_103450404_103453588_RF
8 A 154158478 154217496 154221495 ORF16_6_154154477_154163186_154217494_154220454_RR
9 A 87450097 87560919 87564918 ORF138_2_87446096_87451261_87563076_87564920_RF
10 A 28274699 28329776 28333775 ORF198_9_28270698_28275294_28314155_28333777_RF
11 A 30093466 30144612 30148611 ORF151_12_30089465_30094558_30144610_30146709_RR
12 A 29329558 29376363 29380362 ORF175_19_29325557_29328725_29376361_29378170_RR
13 B 47008708 47065707 47069706 ORF198_6_47004707_47009616_47060758_47069708_RF
14 B 76063006 76127904 76131903 ORF161_15_76059101_76063008_76127902_76129439_FR
15 B 94757904 94818741 94822740 ORF18_9_94753448_94757906_94818790_94822742_FF
16 B 37862830 37889309 37893308 ORF19_4_37859966_37862832_37889307_37892348_FR
17 B 41560027 41620526 41624525 ORF115_8_41556026_41557719_41620524_41625614_RR
18 B 53026229 53104497 53108496 ORF18_5_53020744_53026231_53104495_53107169_FR
19 B 10217511 10289603 10293602 ORF13_3_10213510_10218995_10289864_10293604_RF
20 B 104864980 104945455 104949454 ORF16_2_104860979_104864045_104945453_104950314_RR
21 B 49176114 49215817 49219816 ORF19_11_49172113_49176734_49212875_49219818_RF
22 B 14300087 14351874 14355873 ORF138_5_14296086_14298950_14351872_14353515_RR
23 B 14300087 14364875 14368874 ORF191_5_14296086_14298950_14364873_14369388_RR
24 B 151880299 151947329 151951328 ORF11_4_151874649_151880301_151939544_151951330_FF
25 B 42097751 42135670 42139669 ORF170_2_42093750_42101196_42135668_42138124_RR
26 B 98707843 98720147 98724146 ORF186_1_98703842_98709502_98720841_98724148_RF
27 B 28333775 28370859 28374858 ORF197_9_28314155_28333777_28371887_28374860_FF
28 B 169234823 169319272 169323271 ORF121_2_169230822_169232519_169312990_169323273_RF
29 B 61285290 61298115 61302114 ORF196_18_61281289_61284639_61298113_61310562_RR
30 B 68365967 68412847 68416846 ORF187_2_68359452_68365969_68410496_68416848_FF
31 B 229800282 229851717 229855716 ORF147_1_229796281_229797522_229849427_229855718_RF
32 B 14300087 14331607 14335606 ORF180_5_14296086_14298950_14331605_14334109_RR
33 B 151880299 152011204 152015203 ORF18_4_151874649_151880301_152011202_152016397_FR
34 B 101909239 101950545 101954544 ORF196_8_101906298_101909241_101944457_101954546_FF
35 B 71852443 71890859 71894858 ORF158_2_71849462_71852445_71889643_71894860_FF
36 B 122392024 122423623 122427622 ORF1_2_122384211_122392026_122423621_122431761_FR
37 B 99818412 99882696 99886695 ORF18_14_99815362_99818414_99884900_99886697_FF
38 B 14300087 14319860 14323859 ORF143_5_14296086_14298950_14319858_14323303_RR
39 B 50683893 50716473 50720472 ORF168_13_50679892_50686027_50716471_50721185_RR
40 B 84117144 84155781 84159780 ORF14_3_84107388_84117146_84158429_84159782_FF
41 B 152809366 152824655 152828654 ORF103_1_152785124_152809368_152824653_152831895_FR
42 B 14300087 14334111 14338110 ORF176_5_14296086_14298950_14334109_14335762_RR
43 B 23013471 23046339 23050338 ORF14_10_23011505_23013473_23046337_23050583_FR
44 B 122422530 122487475 122491474 ORF106_2_122420370_122422532_122487405_122491476_FF
45 B 98688920 98705501 98709500 ORF199_1_98683897_98688922_98703842_98709502_FF
46 B 116956518 117001586 117005585 ORF184_1_116953472_116956520_117001584_117004481_FR
47 B 104618223 104659697 104663696 ORF147_2_104614222_104616408_104659695_104660711_RR
48 B 152930116 153001410 153005409 ORF14_6_152926115_152930237_153001408_153002544_RR
49 B 38155474 38171881 38175880 ORF158_2_38148629_38155476_38173151_38175882_FF
50 B 104242117 104307402 104311401 ORF123_10_104238473_104242119_104302206_104311403_FF
51 B 86199748 86251007 86255006 ORF16_11_86195747_86200973_86253845_86255008_RF
表8.1g
編號 群組 PCR- 引子 1_ID PCR_ 引子 1 PCR- 引子 2_ID PCR_ 引子 2
1 A OBD159_917 GCGTTGGAGAAGACCTCAGCCAT OBD159_919 AAACGGGTCTCCACGGCACCAAG
2 A OBD159_849 CAGTGGTAATCTATGGGTGGTAGGAA OBD159_851 GGTGACTGACAGCCAAATCCAATGGG
3 A OBD159_1345 AGAATGGGTCTTACTTTGAAAATA OBD159_1347 CTTTTATTTTAGATACAGTGGTGT
4 A OBD159_949 TCACCCAGTTTCTGCTGTCAATGC OBD159_951 ATCAGTGTTTTCTCCTCTCAAATA
5 A OBD159_777 ACAAAATAGAACCCTGGTCCCACC OBD159_779 GGAAAATCTAAAAGTAATGGACAAA
6 A OBD159_965 GCATAGGGTAGTTGCTCCTTGAGTTT OBD159_967 ACACGGTCCCTGACTCAAGATGGTTG
7 A OBD159_929 GTGTTCATTACCTGATTTGATTTA OBD159_931 TCTTATTTCCCAAGGCTCAAAAGC
8 A OBD159_1125 TGGCAGTCATCAAAATCGCTTCTA OBD159_1127 CAGACAAAGCAAAAGATTTCCTAT
9 A OBD159_953 AATGAACTATCAGGCTATGTAAAA OBD159_955 TACAGTATTTGAGTCACAGGCTGC
10 A OBD159_1357 GAAAACCAGTCAATCCTCAAGTGTGC OBD159_1359 CTCAAGTCCTCATCTGTAGAGTCTGG
11 A OBD159_1065 AGGCTTCCTTGTTGTGTTCATAAT OBD159_1067 TTCTTCCCTCAGCCATCCATTTGG
12 A OBD159_1221 AGATGTGTGTGGGCTCTCGGGCT OBD159_1223 GTCACCGTCCCCAGCAAGAAAGA
13 B OBD159_3649 GAGATGGGTTGCTGGCTGGAGTCTTCTG OBD159_3651 CTGCCCTTGTATTTCTGACTCCGTAACC
14 B OBD159_3653 GGGAGCATCACTATCTTCTTCAGTTGGG OBD159_3655 GCAGCCATTCCACTTGACCCTCTGTATC
15 B OBD159_3657 GCCACAGCCACCATCAGAATGAAGTT OBD159_3659 TCATCTCAGTTGCTTTCTGCTGGAGC
16 B OBD159_3661 CTTACAGCCTTCCAAAATAACTCCAG OBD159_3663 ATGGCATTCCCTGATTTCCCTGGATG
17 B OBD159_3665 TCTTACATCACACCACATCCCCAAAT OBD159_3667 TGGCACTCTCACCAAGACAACCTCAG
18 B OBD159_3669 CACCAATCCCTACATTTTCATCCTCA OBD159_3671 AAGAAAGGAGCAAGCCAAGGATGCCT
19 B OBD159_3673 TCTGTTGCGGGTCTCTTGAGGGC OBD159_3675 GACTGGGCACACAGGAAGCACTA
20 B OBD159_3677 CCTGGAACTTGGGCAAACTAAACTCC OBD159_3679 GAACTCCAAACACATACCCCTGACAG
21 B OBD159_3681 GAGCAGGAAAGTCAAAGGAAAGGAGG OBD159_3683 GCCAAAGAAATGGAATGCTGATGAAT
22 B OBD159_3685 GTGCGGGATTCAGACCTTCAGCA OBD159_3687 ACTACCTGGAAAGGGAGACCCCG
23 B OBD159_3689 GGTGCGGGATTCAGACCTTCAGC OBD159_3691 GCAGGCACAATCCTTCCCAATGC
24 B OBD159_3693 GCTATCTATCACTCAGGGCTTTCCAGGG OBD159_3695 GCCTTGGCTACGGACTGTCAACTCAGC
25 B OBD159_3697 TCCATCCTTCTCACAGCAGCCAAGAG OBD159_3699 GGGATTGAGCAGACAGATTAGTGAAA
26 B OBD159_3701 TATTTTTCCTGATTGTAAAGTAAAT OBD159_3703 GATTTCCCAACTCAGTTAAAAA
27 B OBD159_3705 TGAAAACCAGTCAATCCTCAAGTGTGC OBD159_3707 AACCAGAGCCCCAAATAAGGATGGAAGC
28 B OBD159_3709 GGGGAAATGTTGCAATTAACTAATTTT OBD159_3711 TTAACTATTGGTTATAAGAATAAA
29 B OBD159_3713 TGGTATTGCTCCACTTCTGGCACTGC OBD159_3715 AACAGTCTTCTTCCTGCCTCACTACT
30 B OBD159_3717 CTCTTCTATGGAGGTTTCTTGGAGGGAC OBD159_3719 CAGTGGGCAGAAGGGCGGGTTACAGC
31 B OBD159_3721 CCACCGATTTATTGCCCTGTAGGACA OBD159_3723 GATTGATGAAGTGGAAGTGGCAGGCA
32 B OBD159_3725 GGTGCGGGATTCAGACCTTCAGC OBD159_3727 CAAGTGCTTCCTGAGGTGACTGC
33 B OBD159_3729 GCTATCTATCACTCAGGGCTTTCCAGGG OBD159_3731 CCCATCCTAAAGTGACTGAACGGCAGCA
34 B OBD159_3733 GAGCCCATCAGAGCACCCATTCT OBD159_3735 CTGACCTCTCCTGGCTTCCTGCT
35 B OBD159_3737 GCATCTCCGCCGCCTACTTGGGC OBD159_3739 TCTCACCCCTCCCCAGGATGGCTCCACT
36 B OBD159_3741 GGAATCCAGCCAAGGGAGGCATTAGGAC OBD159_3743 GAGAGAGCAACAGAGGGCAGGGTCCC
37 B OBD159_3745 CCAAACCAAGGAGGTGACAATGGAGG OBD159_3747 GGACTCCTCCTCTATCAAGCCTTATT
38 B OBD159_3749 GTGCGGGATTCAGACCTTCAGCA OBD159_3751 CGCCACGCCTGACTACCATCCAA
39 B OBD159_3753 TCACTGGCATTCATAGATGTGGTCAC OBD159_3755 GACATCACGGAAAAGGTAGCCCAAGG
40 B OBD159_3757 CTCCCCTACCTTTTCCTGCCTTCTTC OBD159_3759 TCAGAACCAGGCAGAGCCAATGAAAA
41 B OBD159_3761 GACATTTGGTGACCCATTACTCAACA OBD159_3763 GCTATGAGGCAAATCAAAAGTAAAGC
42 B OBD159_3765 GGTGCGGGATTCAGACCTTCAGC OBD159_3767 GCCTCACAAAAGCGGCAGGACAT
43 B OBD159_3769 CCTGGAATAGCCTTGCTTGTTTTGTGGC OBD159_3771 GCTTTCTATCCTGTAAGAGTCTATGC
44 B OBD159_3773 GTTGAGGGTGAAGGCTAACAGTTTTGAG OBD159_3775 GGGAAAAGGCAAGCACCGCTCTCAGC
45 B OBD159_3777 CCCAGTTATTTCTACAGTTTGGAAGC OBD159_3779 CCTGCTTCTGAGACCTCCACAGTGTT
46 B OBD159_3781 CCGCTGTGTTTGGGTATGTAGGATTC OBD159_3783 GGTTGAGTGACAAATGCTGTGCTCTC
47 B OBD159_3785 GGAGGAAGCCCAGCCACTTGAGT OBD159_3787 CAGCAGAAATCTCTCCCTCAGGC
48 B OBD159_3789 GAAGAGGAGGTATTCCACTGTCTGAA OBD159_3791 GGTTTCTGGCTTCAGCACGAGTGGTA
49 B OBD159_3793 GCTCTGCCTTTCATTTACACACAGGA OBD159_3795 GGTCTGTGATTTGGTGGCTGCGTGAA
50 B OBD159_3797 GGGAAGAGGCTACATTGTTATGGATA OBD159_3799 CAGGCTCATTGGCTTTTCCCAGGTCT
51 B OBD159_3801 AGAGACAGGGTTTCACCATATTGGCCAGGA OBD159_3803 GAAGATATTTTGTTATTTCCAA
表8.1h
編號 群組 探針 基因座 Probe_Count_Total
52 B ORF13_11_87926403_87934326_87969207_88006264_FF N/A N/A
53 B ORF107_5_14296086_14298950_14319858_14323303_RR N/A N/A
54 B ORF122_14_85582584_85584999_85612892_85619304_RR N/A N/A
55 B ORF18_1_177061512_177062775_177182650_177184039_RF N/A N/A
56 B ORF10_18_10266375_10268783_10331127_10332730_FR N/A N/A
57 B ORF175_18_28083723_28088432_28142420_28147707_FR N/A N/A
58 B ORF186_15_89407225_89408856_89469667_89472380_FF N/A N/A
59 B ORF18_1_246640282_246644196_246664999_246668825_RR N/A N/A
60 B ORF10_2_66470757_66475654_66592400_66595314_FR N/A N/A
61 B ORF13_6_168253924_168260809_168295264_168300543_RF N/A N/A
62 B ORF171_9_8138555_8143223_8167171_8181381_FR N/A N/A
63 B ORF153_1_116579148_116582139_116593950_116598324_FR N/A N/A
64 B ORF11_16_75911508_75913466_75948233_75952817_FR N/A N/A
65 B ORF112_3_116555344_116556412_116607020_116611600_RR N/A N/A
66 B ORF150_1_111535220_111538688_111567009_111572658_RF N/A N/A
67 B ORF148_3_64194265_64195323_64266976_64268244_FR N/A N/A
68 B ORF185_6_139965927_139972052_140005899_140012028_RF N/A N/A
69 B ORF172_2_197111951_197117459_197161229_197162625_RR N/A N/A
70 B ORF16_16_51538978_51545978_51556847_51564565_RF N/A N/A
71 B ORF100_2_102942687_102944341_102983000_102995309_FR N/A N/A
72 B ORF16_12_134194_137994_79804_82702_RR N/A N/A
73 B ORF133_4_109570279_109575929_109606195_109611946_RF N/A N/A
74 B ORF123_22_26723696_26728605_26756491_26757562_RF N/A N/A
75 B ORF157_8_29047786_29048949_29063470_29065562_FR N/A N/A
76 B ORF185_6_114223082_114225950_114291528_114299574_RR N/A N/A
77 C ORF138_12_81301126_81306761_81329842_81332845_RR N/A N/A
78 C ORF125_4_152168385_152172738_152221305_152227696_FF N/A N/A
79 C ORF185_19_52224152_52228867_52265664_52267714_RF N/A N/A
80 C ORF173_8_86595631_86604532_86648386_86651477_RR N/A N/A
81 C ORF10_2_120634320_120644277_120657582_120661506_FF N/A N/A
82 C ORF100_6_27443471_27448356_27474081_27477940_RF N/A N/A
83 C ORF17_12_13672704_13680228_13723880_13729648_RR N/A N/A
84 C ORF18_5_149610432_149612632_149663575_149665859_RR N/A N/A
85 C ORF136_2_98173571_98177804_98209752_98213279_FR N/A N/A
86 C ORF151_5_136165905_136172620_136234001_136237401_FF N/A N/A
87 C ORF182_2_198099686_198102962_198137324_198146976_RR N/A N/A
88 C ORF171_14_68293666_68299109_68325745_68327713_RF N/A N/A
89 C ORF108_2_209644804_209647666_209684451_209692640_RF N/A N/A
90 C ORF160_4_152757074_152760709_152780762_152787205_RF N/A N/A
91 C ORF127_7_8358874_8360456_8389864_8393728_RR N/A N/A
92 C ORF145_5_14296086_14298950_14351872_14353515_RR N/A N/A
93 C ORF124_12_130248318_130252496_130274212_130276586_FF N/A N/A
94 C ORF114_5_14296086_14298950_14334109_14335762_RR N/A N/A
95 C ORF134_2_2294551_2296479_2317980_2323920_FR N/A N/A
96 C ORF198_12_130189601_130192155_130248318_130252496_RR N/A N/A
97 C ORF164_10_85560664_85563397_85593191_85595358_RR N/A N/A
98 C ORF132_5_107295107_107306594_107372426_107377048_RF N/A N/A
99 C ORF135_14_29277224_29280917_29340222_29341759_RF N/A N/A
100 C ORF118_15_68642931_68645237_68673635_68679559_RF N/A N/A
101 C ORF123_5_14296086_14298950_14364873_14369388_RR N/A N/A
102 C ORF103_5_14296086_14298950_14331605_14334109_RR N/A N/A
表8.2a
編號 群組 Probe_Count_Sig HyperG_Stats FDR_HyperG Percent_Sig logFC AveExpr
52 B N/A N/A N/A N/A -0.586898321 -0.586898321
53 B N/A N/A N/A N/A -0.586827812 -0.586827812
54 B N/A N/A N/A N/A -0.586051104 -0.586051104
55 B N/A N/A N/A N/A -0.584927271 -0.584927271
56 B N/A N/A N/A N/A -0.584684418 -0.584684418
57 B N/A N/A N/A N/A -0.583908766 -0.583908766
58 B N/A N/A N/A N/A -0.582395639 -0.582395639
59 B N/A N/A N/A N/A -0.581165242 -0.581165242
60 B N/A N/A N/A N/A -0.580915659 -0.580915659
61 B N/A N/A N/A N/A -0.580259909 -0.580259909
62 B N/A N/A N/A N/A -0.57904454 -0.57904454
63 B N/A N/A N/A N/A -0.578157078 -0.578157078
64 B N/A N/A N/A N/A -0.577141251 -0.577141251
65 B N/A N/A N/A N/A -0.575549154 -0.575549154
66 B N/A N/A N/A N/A -0.574427555 -0.574427555
67 B N/A N/A N/A N/A -0.57288621 -0.57288621
68 B N/A N/A N/A N/A -0.572175196 -0.572175196
69 B N/A N/A N/A N/A -0.570805397 -0.570805397
70 B N/A N/A N/A N/A -0.569367362 -0.569367362
71 B N/A N/A N/A N/A -0.567678147 -0.567678147
72 B N/A N/A N/A N/A -0.567184946 -0.567184946
73 B N/A N/A N/A N/A -0.56711622 -0.56711622
74 B N/A N/A N/A N/A -0.566444933 -0.566444933
75 B N/A N/A N/A N/A -0.565375444 -0.565375444
76 B N/A N/A N/A N/A -0.564634919 -0.564634919
77 C N/A N/A N/A N/A -0.702767919 -0.702767919
78 C N/A N/A N/A N/A -0.698964773 -0.698964773
79 C N/A N/A N/A N/A -0.696908521 -0.696908521
80 C N/A N/A N/A N/A -0.696509019 -0.696509019
81 C N/A N/A N/A N/A -0.690656622 -0.690656622
82 C N/A N/A N/A N/A -0.690344952 -0.690344952
83 C N/A N/A N/A N/A -0.684415014 -0.684415014
84 C N/A N/A N/A N/A -0.683595798 -0.683595798
85 C N/A N/A N/A N/A -0.683573062 -0.683573062
86 C N/A N/A N/A N/A -0.68352752 -0.68352752
87 C N/A N/A N/A N/A -0.67957191 -0.67957191
88 C N/A N/A N/A N/A -0.673242334 -0.673242334
89 C N/A N/A N/A N/A -0.668516451 -0.668516451
90 C N/A N/A N/A N/A -0.663486882 -0.663486882
91 C N/A N/A N/A N/A -0.66262386 -0.66262386
92 C N/A N/A N/A N/A -0.661216696 -0.661216696
93 C N/A N/A N/A N/A -0.660275172 -0.660275172
94 C N/A N/A N/A N/A -0.658216308 -0.658216308
95 C N/A N/A N/A N/A -0.656777859 -0.656777859
96 C N/A N/A N/A N/A -0.653345364 -0.653345364
97 C N/A N/A N/A N/A -0.652291019 -0.652291019
98 C N/A N/A N/A N/A -0.650225719 -0.650225719
99 C N/A N/A N/A N/A -0.649623586 -0.649623586
100 C N/A N/A N/A N/A -0.648661823 -0.648661823
101 C N/A N/A N/A N/A -0.644293882 -0.644293882
102 C N/A N/A N/A N/A -0.640456524 -0.640456524
表8.2b
編號 群組 t P值 adj.P.Val B FC
52 B -5.395369562 0.000162149 0.001167317 0.758034728 0.665772728
53 B -9.155938388 0.000000931 0.0000383 6.077783362 0.665805267
54 B -4.252417142 0.001126266 0.004875795 -1.234133935 0.666163815
55 B -12.68957312 0.0000000263 0.00000482 9.673892039 0.666682947
56 B -10.64975836 0.000000183 0.0000142 7.731630617 0.666795181
57 B -7.583585093 0.00000653 0.000131431 4.076805415 0.667153773
58 B -4.385539898 0.000890811 0.004095481 -0.99425845 0.667853865
59 B -8.108130314 0.00000331 0.0000844 4.777078763 0.668423684
60 B -4.274667755 0.00108281 0.004732596 -1.193919829 0.66853933
61 B -10.24766131 0.000000278 0.0000183 7.307670683 0.668843271
62 B -11.6199294 0.0000000702 0.00000804 8.69644406 0.669406962
63 B -7.93551324 0.00000412 0.0000975 4.550417934 0.669818868
64 B -9.216088835 0.000000869 0.0000367 6.14872636 0.670290666
65 B -7.440743794 0.00000790 0.000148427 3.880068379 0.671030779
66 B -13.42437933 0.0000000140 0.00000340 10.29841244 0.671552663
67 B -6.245767362 0.0000431 0.00045868 2.127000784 0.672270519
68 B -7.12134428 0.0000122 0.000198377 3.430489476 0.672601921
69 B -7.088625782 0.0000128 0.000204264 3.383670075 0.673240841
70 B -7.524455646 0.00000706 0.000137939 3.995685688 0.673912242
71 B -14.84926608 0.00000000445 0.00000192 11.41310563 0.674701771
72 B -10.21791369 0.000000287 0.0000186 7.27571193 0.674932464
73 B -9.533328384 0.000000606 0.0000292 6.516570726 0.674964617
74 B -5.764018355 0.0000902 0.00076953 1.364008245 0.675278751
75 B -10.96015665 0.000000134 0.0000117 8.048992793 0.67577953
76 B -7.361075142 0.00000880 0.000159439 3.769187822 0.676126492
77 C -10.48346697 0.000000217 0.0000158 7.558089961 0.614392317
78 C -7.705331156 0.00000556 0.000118449 4.242417809 0.616014078
79 C -7.679506884 0.00000575 0.000121229 4.207446703 0.6168927
80 C -6.039894092 0.0000589 0.000570983 1.804960079 0.617063549
81 C -5.295901523 0.000190586 0.001312022 0.591296967 0.619571796
82 C -4.921711384 0.000354375 0.002068057 -0.047884458 0.619705659
83 C -5.958715792 0.0000667 0.000622892 1.676326053 0.62225809
84 C -5.375009075 0.000167583 0.001195029 0.724015211 0.622611531
85 C -2.836188313 0.015022234 0.035904842 -3.838744638 0.622621343
86 C -8.972838358 0.00000115 0.0000437 5.859426477 0.622640998
87 C -6.377946527 0.0000354 0.000401584 2.330609292 0.62435051
88 C -5.932985254 0.0000694 0.000640919 1.635358941 0.627095758
89 C -12.67563219 0.0000000266 0.00000483 9.661689053 0.629153324
90 C -8.071203637 0.00000347 0.0000870 4.728897646 0.631350526
91 C -8.777886199 0.00000145 0.0000506 5.622886101 0.631728314
92 C -10.4590631 0.000000223 0.0000160 7.532411369 0.632344784
93 C -5.839220812 0.0000802 0.000708795 1.48527768 0.632757597
94 C -14.07522205 0.00000000818 0.00000260 10.82253301 0.633661247
95 C -6.411983432 0.0000337 0.000388614 2.382641664 0.634293359
96 C -5.445245296 0.000149608 0.001102029 0.841128152 0.635804281
97 C -10.42177056 0.000000232 0.0000163 7.49306565 0.636269107
98 C -2.323991609 0.03851793 0.076770932 -4.74879567 0.637180615
99 C -5.380251013 0.000166166 0.001187454 0.732779215 0.637446608
100 C -5.867036849 0.0000768 0.000687439 1.529930436 0.6378717
101 C -11.93737725 0.0000000521 0.00000676 8.995489036 0.639805863
102 C -12.94887187 0.0000000210 0.00000422 9.898415521 0.641509918
表8.2c
編號 群組 FC_1 LS 偵測到之環
52 B -1.502014063 -1 重度自閉症
53 B -1.501940657 -1 重度自閉症
54 B -1.50113227 -1 重度自閉症
55 B -1.499963371 -1 重度自閉症
56 B -1.499710899 -1 重度自閉症
57 B -1.49890481 -1 重度自閉症
58 B -1.497333553 -1 重度自閉症
59 B -1.496057102 -1 重度自閉症
60 B -1.49579831 -1 重度自閉症
61 B -1.495118578 -1 重度自閉症
62 B -1.493859575 -1 重度自閉症
63 B -1.492940924 -1 重度自閉症
64 B -1.491890087 -1 重度自閉症
65 B -1.490244608 -1 重度自閉症
66 B -1.489086493 -1 重度自閉症
67 B -1.487496435 -1 重度自閉症
68 B -1.486763521 -1 重度自閉症
69 B -1.48535255 -1 重度自閉症
70 B -1.483872733 -1 重度自閉症
71 B -1.482136321 -1 重度自閉症
72 B -1.481629723 -1 重度自閉症
73 B -1.481559144 -1 重度自閉症
74 B -1.480869934 -1 重度自閉症
75 B -1.479772552 -1 重度自閉症
76 B -1.47901319 -1 重度自閉症
77 C -1.627624519 -1 重度自閉症
78 C -1.623339524 -1 重度自閉症
79 C -1.621027449 -1 重度自閉症
80 C -1.620578627 -1 重度自閉症
81 C -1.614017949 -1 重度自閉症
82 C -1.613669305 -1 重度自閉症
83 C -1.60705022 -1 重度自閉症
84 C -1.606137937 -1 重度自閉症
85 C -1.606112625 -1 重度自閉症
86 C -1.606061925 -1 重度自閉症
87 C -1.601664423 -1 重度自閉症
88 C -1.59465279 -1 重度自閉症
89 C -1.58943768 -1 重度自閉症
90 C -1.58390618 -1 重度自閉症
91 C -1.582958968 -1 重度自閉症
92 C -1.581415748 -1 重度自閉症
93 C -1.580384029 -1 重度自閉症
94 C -1.578130278 -1 重度自閉症
95 C -1.576557576 -1 重度自閉症
96 C -1.572811051 -1 重度自閉症
97 C -1.571662035 -1 重度自閉症
98 C -1.569413721 -1 重度自閉症
99 C -1.568758837 -1 重度自閉症
100 C -1.567713383 -1 重度自閉症
101 C -1.562974111 -1 重度自閉症
102 C -1.558822352 -1 重度自閉症
表8.2d
      探針序列 探針位置
編號 群組 60 mer Chr
52 B GAAGTTTCAACTTGATTCTTTCTAACTTTCGATTTTTTAAAAATTGTCATTCTGACTGGA 11
53 B AACCCCTCTGAGCAAATCTCCCACTGCCTCGAGGTTAATTTTTTCCCCTCTTAATAAGCG 5
54 B ATTTAATTCACACAGTAGGATTATAAGGTCGACCGAAATGTGTATTCCTCTTGTGAAGGA 14
55 B TCCTTCCACTTTCAGTTCCCCATACACATCGAAAAAAATATCAAGGTGAAAATTCAAGTT 1
56 B CATCTCTTTACTATTAATTCTTTCCTGTTCGATCACTCTATCTATCTATCATCTCTCACC 18
57 B CTGACACTTGAACCATAATTTTTTTCATTCGAAAGGGATATAAAAAATTCCAAGTATTAA 18
58 B CCTGGGTGGAATTCACCCAGGAATACAATCGATTTCCTCATCTATAAAAATGAAGCTGAC 15
59 B TACAACACATAAACATTAGCAAGTTGAATCGACTTTGCTCTCAGGTAGTCCCATTATGTG 1
60 B CAACATCCATGGAAGTTGCTCAGAAGAATCGAAAAAAAAATAAAAAAATAAAAAAATAAA 2
61 B TGAAGCTTTAGTTTAGCGACTAAAGTCATCGATTTTTTTCACATCAACGTTACACCAAAA 6
62 B CCCCACTCTGCCCTCAATTGTGGTTCATTCGAATCTCTCTAGTAATAAAAACATCACTGT 9
63 B TCTGCATAAATGACTCAATACAAGTTTTTCGAATGACATTCATATGGGCAAAAATTATGC 1
64 B TGAAAACAAAGTTGATATCTCACTCACTTCGAGGTGTGAGAGGGATTTGCTATTACTGTC 16
65 B CTACTGAGTCATATTATTCGCCTTTTTTTCGAATATTGCCTTCTCCTCAACCACCACTGG 3
66 B GCTTGATCTTTCCACATCCTCTATCTTTTCGAAATGTATCCACCCACCCCACCTCTAAAC 1
67 B GCATTTTTATGAAATTAAATGTCCGTATTCGATTCTCAACCTCTTGCTTAGGTACACACA 3
68 B TAAACTTTTAAAGAAAGCAAGAATTGCATCGAAGGCTTCTGTAAGCATATATGTAAAGCT 6
69 B TTAATCTGTGTCAGGAAATTTCATAATTTCGAAGATAAGGCATATGGGAGATGCATCTCT 2
70 B ACAAAAATTAACTCAAAATTGATCATCATCGATGATACTTAACAACATTTCAAACCAGGC 16
71 B CTGGATCTGTTATTTATCTAATTATACCTCGATTTCACCAAGTTTGCAAAAGATTCTGTG 2
72 B ACATAGTGGGCCTTCAATGAGTGTGTATTCGAATTCCTGCCCGCCCCCACACCTTCCAGC 12
73 B TTTTGTAACAGAATTTCTCTTGATCTCCTCGAAGATCAGGTGCTGTATCTTTTATATCTT 4
74 B TTAATCTACTCTCTATCTGTGTAGATTCTCGAGAACTAGCCAGTAACAAAAGCTGTGATT 22
75 B AGATAATTTAGGGATCTATTTGCTTTTTTCGATAACCTCCTGACCTTGTCTTTCCTATAA 8
76 B TATATACCTCAGCAAAAAAAAAATTAAATCGATTTGTAGATACAGGCAATGCCATGGAGA 6
77 C CCATCCCCACCTCTTTCCTACCTGCCCTTCGATGCTTCCAGTGATTAGACCCCGGGTCCG 12
78 C AAACTTTAAAACAAAATGAAGTTCTAATTCGACACTATTGAATATATCATAGCAGTTAGA 4
79 C CCCTGTCTCTAAAAAATAATAATAATAATCGAGATGATGGAAGTAAGAATAGTGGTTATT 19
80 C AGATTAAAAGTATGAGCAGAGATAAGACTCGAACCATTTTGCTACCAATAAACTGCTTTA 8
81 C TTTTAGACACAAAAAATTACAGGTACATTCGATTGTGTAAACAGGGATAATTATAATATT 2
82 C TGTCCCTCTTCCTCATTTATCTACTTAGTCGATATGTATGTAATCAATCCATTCAATATC 6
83 C TGAGATAATAGAATAGAACATTTTCATATCGATCCAGAGGAAAAAAACTAATAGTGGCAA 12
84 C TTTTTAATCTTATAATCACGTTACCCATTCGAAATGTACACTTAAAAAGGGTGAATTAGG 5
85 C CTCTTTCAAAACCCTTGCGAGGATTGGTTCGAATGTGATATTTCTGGTTCTTGGTATAAT 2
86 C GGGTTTGTTGTCAAATGTTAATCGTAATTCGAAGATGAAGAAAACACAGCTTCTTCCCTC 5
87 C TTGTCTAATAAACGTCATAAAGAGATAATCGAAAATTTGAAATAATTACTAAGAACGGTT 2
88 C TCTAACCATTATGAGTAGATATTAATCTTCGAGGCTTATTTAAAGACTGCCTCTTTCACA 14
89 C CCCGATTACTTCAGATTTACTTACAGCCTCGAAGAAAAGGTATGGAAAACTTCAAAATTT 2
90 C AGTTAATGGTATTAAGGATTTCAGTTCATCGAGTTTCAGTGCATTTTTTACTTACTTTGA 4
91 C CATGCAAATGCTGAAGAATACCTAGTTTTCGATTTAATAGTTTAGCATCAGAAGCAGACC 7
92 C AACCCCTCTGAGCAAATCTCCCACTGCCTCGACTTAACTGGAGGCTTGGTCCTTTCCGAG 5
93 C TTAAAATATTCTGGAAGACAATTATCTATCGAAGAAATAAAAACATCAATCAAGGACTGG 12
94 C AACCCCTCTGAGCAAATCTCCCACTGCCTCGATTTCCTCGCCTGTGAAATGGGAAATCAG 5
95 C AATATAAACAAAAGCTTTGTAATTACTATCGATCTTGTAGGAGGAAGGACGAGATGTGTG 2
96 C AAGGTTGTTGAATGAATAAAAGAGGTACTCGATAAGGAAACAGTAGAGAGATTAATTATC 12
97 C AGAAAATATAGCAAATATCTTTATGACCTCGACTCCCCTAGAGGAAATATATTTTATTTC 10
98 C ATATAATGTCAGCATTTCAAAACAGCACTCGATGGAAAACAATGCCACAGGCAAAGAACC 5
99 C TGGCTCATTCATTTACTTATTTATTCATTCGATATTCTCTCCAGATTGTGCATCAAGGTT 14
100 C TGCAGATGATAATAATAACTACCATTTATCGAGAATGTTCTGCATGGAAAAGACAGAGAA 15
101 C AACCCCTCTGAGCAAATCTCCCACTGCCTCGACTTCCCGGAAATTCTGACCTGTAGCATT 5
102 C AACCCCTCTGAGCAAATCTCCCACTGCCTCGAACCTCATGTTTAGGTGGTGGAAGCGAGT 5
表8.2e
      探針位置 4 kb序列位置
編號 群組 起點 1 終點 1 起點 2 終點 2 Chr 起點 1
52 B 87934295 87934324 88006233 88006262 11 87930325
53 B 14296088 14296117 14319860 14319889 5 14296088
54 B 85582586 85582615 85612894 85612923 14 85582586
55 B 177061514 177061543 177184008 177184037 1 177061514
56 B 10268752 10268781 10331129 10331158 18 10264782
57 B 28088401 28088430 28142422 28142451 18 28084431
58 B 89408825 89408854 89472349 89472378 15 89404855
59 B 246640284 246640313 246665001 246665030 1 246640284
60 B 66475623 66475652 66592402 66592431 2 66471653
61 B 168253926 168253955 168300512 168300541 6 168253926
62 B 8143192 8143221 8167173 8167202 9 8139222
63 B 116582108 116582137 116593952 116593981 1 116578138
64 B 75913435 75913464 75948235 75948264 16 75909465
65 B 116555346 116555375 116607022 116607051 3 116555346
66 B 111535222 111535251 111572627 111572656 1 111535222
67 B 64195292 64195321 64266978 64267007 3 64191322
68 B 139965929 139965958 140011997 140012026 6 139965929
69 B 197111953 197111982 197161231 197161260 2 197111953
70 B 51538980 51539009 51564534 51564563 16 51538980
71 B 102944310 102944339 102983002 102983031 2 102940340
72 B 134196 134225 79806 79835 12 134196
73 B 109570281 109570310 109611915 109611944 4 109570281
74 B 26723698 26723727 26757531 26757560 22 26723698
75 B 29048918 29048947 29063472 29063501 8 29044948
76 B 114223084 114223113 114291530 114291559 6 114223084
77 C 81301128 81301157 81329844 81329873 12 81301128
78 C 152172707 152172736 152227665 152227694 4 152168737
79 C 52224154 52224183 52267683 52267712 19 52224154
80 C 86595633 86595662 86648388 86648417 8 86595633
81 C 120644246 120644275 120661475 120661504 2 120640276
82 C 27443473 27443502 27477909 27477938 6 27443473
83 C 13672706 13672735 13723882 13723911 12 13672706
84 C 149610434 149610463 149663577 149663606 5 149610434
85 C 98177773 98177802 98209754 98209783 2 98173803
86 C 136172589 136172618 136237370 136237399 5 136168619
87 C 198099688 198099717 198137326 198137355 2 198099688
88 C 68293668 68293697 68327682 68327711 14 68293668
89 C 209644806 209644835 209692609 209692638 2 209644806
90 C 152757076 152757105 152787174 152787203 4 152757076
91 C 8358876 8358905 8389866 8389895 7 8358876
92 C 14296088 14296117 14351874 14351903 5 14296088
93 C 130252465 130252494 130276555 130276584 12 130248495
94 C 14296088 14296117 14334111 14334140 5 14296088
95 C 2296448 2296477 2317982 2318011 2 2292478
96 C 130189603 130189632 130248320 130248349 12 130189603
97 C 85560666 85560695 85593193 85593222 10 85560666
98 C 107295109 107295138 107377017 107377046 5 107295109
99 C 29277226 29277255 29341728 29341757 14 29277226
100 C 68642933 68642962 68679528 68679557 15 68642933
101 C 14296088 14296117 14364875 14364904 5 14296088
102 C 14296088 14296117 14331607 14331636 5 14296088
表8.2f
   C 4 kb序列位置   
編號 群組 終點 1 起點 2 終點 2 探針
52 B 87934324 88002263 88006262 ORF13_11_87926403_87934326_87969207_88006264_FF
53 B 14300087 14319860 14323859 ORF107_5_14296086_14298950_14319858_14323303_RR
54 B 85586585 85612894 85616893 ORF122_14_85582584_85584999_85612892_85619304_RR
55 B 177065513 177180038 177184037 ORF18_1_177061512_177062775_177182650_177184039_RF
56 B 10268781 10331129 10335128 ORF10_18_10266375_10268783_10331127_10332730_FR
57 B 28088430 28142422 28146421 ORF175_18_28083723_28088432_28142420_28147707_FR
58 B 89408854 89468379 89472378 ORF186_15_89407225_89408856_89469667_89472380_FF
59 B 246644283 246665001 246669000 ORF18_1_246640282_246644196_246664999_246668825_RR
60 B 66475652 66592402 66596401 ORF10_2_66470757_66475654_66592400_66595314_FR
61 B 168257925 168296542 168300541 ORF13_6_168253924_168260809_168295264_168300543_RF
62 B 8143221 8167173 8171172 ORF171_9_8138555_8143223_8167171_8181381_FR
63 B 116582137 116593952 116597951 ORF153_1_116579148_116582139_116593950_116598324_FR
64 B 75913464 75948235 75952234 ORF11_16_75911508_75913466_75948233_75952817_FR
65 B 116559345 116607022 116611021 ORF112_3_116555344_116556412_116607020_116611600_RR
66 B 111539221 111568657 111572656 ORF150_1_111535220_111538688_111567009_111572658_RF
67 B 64195321 64266978 64270977 ORF148_3_64194265_64195323_64266976_64268244_FR
68 B 139969928 140008027 140012026 ORF185_6_139965927_139972052_140005899_140012028_RF
69 B 197115952 197161231 197165230 ORF172_2_197111951_197117459_197161229_197162625_RR
70 B 51542979 51560564 51564563 ORF16_16_51538978_51545978_51556847_51564565_RF
71 B 102944339 102983002 102987001 ORF100_2_102942687_102944341_102983000_102995309_FR
72 B 138195 79806 83805 ORF16_12_134194_137994_79804_82702_RR
73 B 109574280 109607945 109611944 ORF133_4_109570279_109575929_109606195_109611946_RF
74 B 26727697 26753561 26757560 ORF123_22_26723696_26728605_26756491_26757562_RF
75 B 29048947 29063472 29067471 ORF157_8_29047786_29048949_29063470_29065562_FR
76 B 114227083 114291530 114295529 ORF185_6_114223082_114225950_114291528_114299574_RR
77 C 81305127 81329844 81333843 ORF138_12_81301126_81306761_81329842_81332845_RR
78 C 152172736 152223695 152227694 ORF125_4_152168385_152172738_152221305_152227696_FF
79 C 52228153 52263713 52267712 ORF185_19_52224152_52228867_52265664_52267714_RF
80 C 86599632 86648388 86652387 ORF173_8_86595631_86604532_86648386_86651477_RR
81 C 120644275 120657505 120661504 ORF10_2_120634320_120644277_120657582_120661506_FF
82 C 27447472 27473939 27477938 ORF100_6_27443471_27448356_27474081_27477940_RF
83 C 13676705 13723882 13727881 ORF17_12_13672704_13680228_13723880_13729648_RR
84 C 149614433 149663577 149667576 ORF18_5_149610432_149612632_149663575_149665859_RR
85 C 98177802 98209754 98213753 ORF136_2_98173571_98177804_98209752_98213279_FR
86 C 136172618 136233400 136237399 ORF151_5_136165905_136172620_136234001_136237401_FF
87 C 198103687 198137326 198141325 ORF182_2_198099686_198102962_198137324_198146976_RR
88 C 68297667 68323712 68327711 ORF171_14_68293666_68299109_68325745_68327713_RF
89 C 209648805 209688639 209692638 ORF108_2_209644804_209647666_209684451_209692640_RF
90 C 152761075 152783204 152787203 ORF160_4_152757074_152760709_152780762_152787205_RF
91 C 8362875 8389866 8393865 ORF127_7_8358874_8360456_8389864_8393728_RR
92 C 14300087 14351874 14355873 ORF145_5_14296086_14298950_14351872_14353515_RR
93 C 130252494 130272585 130276584 ORF124_12_130248318_130252496_130274212_130276586_FF
94 C 14300087 14334111 14338110 ORF114_5_14296086_14298950_14334109_14335762_RR
95 C 2296477 2317982 2321981 ORF134_2_2294551_2296479_2317980_2323920_FR
96 C 130193602 130248320 130252319 ORF198_12_130189601_130192155_130248318_130252496_RR
97 C 85564665 85593193 85597192 ORF164_10_85560664_85563397_85593191_85595358_RR
98 C 107299108 107373047 107377046 ORF132_5_107295107_107306594_107372426_107377048_RF
99 C 29281225 29337758 29341757 ORF135_14_29277224_29280917_29340222_29341759_RF
100 C 68646932 68675558 68679557 ORF118_15_68642931_68645237_68673635_68679559_RF
101 C 14300087 14364875 14368874 ORF123_5_14296086_14298950_14364873_14369388_RR
102 C 14300087 14331607 14335606 ORF103_5_14296086_14298950_14331605_14334109_RR
表8.2g
編號 群組 PCR- 引子 1_ID PCR_ 引子 1 PCR- 引子 2_ID PCR_ 引子 2
52 B OBD159_3805 GCCAATAACCTTCCAGCATCTCCCTGAA OBD159_3807 CCTCTTATCAGATGTATAGTT
53 B OBD159_3809 GTGCGGGATTCAGACCTTCAGCA OBD159_3811 CGCCACGCCTGACTACCATCCAA
54 B OBD159_3813 CCAGGCACCTTATTTGAGATGTCTTC OBD159_3815 GCATACTACTTTACCATTCCACACAG
55 B OBD159_3817 CCCTGGTCATTCTTCCTGTTGGAGAC OBD159_3819 TCGGGAGGTATCAGGTATTCAAACTG
56 B OBD159_3821 GAGCCTCACCAATCCCACTCCCTTCTGG OBD159_3823 GGTGATTCCGATGTGGTCCCAGCCCTG
57 B OBD159_3825 CGTAAGCCCTGAACACGCAAATGAGT OBD159_3827 AGTGGTTCCAAGACAGAGATTGTTCT
58 B OBD159_3829 GGAAAAGTGGCTCCTCTGGGAACCCG OBD159_3831 GACCAGCAAGGACCCCAGTTTCTCCAC
59 B OBD159_3833 CTATTGTCTCCCTTTGTCTTCAGAAATC OBD159_3835 CCACCCCGACAGCATTATTTGACAGTCT
60 B OBD159_3837 CCCTGAGCTTCCTAGCAGCTAAAACAAAG OBD159_3839 TATATTGTTATTGTAATTGCCATTAAATGGT
61 B OBD159_3841 GGGTGGCGATGGAGGAGAGTCAT OBD159_3843 GCAGCAGGTCCTCAGATGATGTC
62 B OBD159_3845 TTTACAGCCCCACCAGCAACACAGGA OBD159_3847 GGGCTGGTATTTTCTTTATCTGGTGG
63 B OBD159_3849 CACCTCCTCCCTCTTCAATCTCC OBD159_3851 GGAGGCACAGTCACAGTCAACGC
64 B OBD159_3853 CGTCTTTCTCCCATACCTTCAAGTCT OBD159_3855 CTGGTCTACCCCTTCCTCCATCTCTA
65 B OBD159_3857 CTCACGACAATCATCTCTCAAAAGGC OBD159_3859 GCTGCTGCTTCTCTCCAATGTCTA
66 B OBD159_3861 CACCACCCCATCAATCTGCTCTG OBD159_3863 GACTGCTGGGTCCTTTTGCCGTG
67 B OBD159_3865 GCCTTTCCTTTCTGGCATCATCTGTT OBD159_3867 GGAAAGATTGTGGGTAGGTGCTGGGT
68 B OBD159_3869 CAGATTGTGAGGCACCCTTGGATCTTGACCT OBD159_3871 TAGAAACATAAAATATCCTTT
69 B OBD159_3873 GATGAAAATACATTCTCTCTATTGGG OBD159_3875 CACATGGGCTAAGAGGCCCTAGAA
70 B OBD159_3877 CCACACAAATAGACTTGACTGAGTTT OBD159_3879 GGCTATGGGAGGGAGAGGAAGAAATA
71 B OBD159_3881 CATCTCAGGAAATGAAATAGCCCTCAGC OBD159_3883 CTATGGACTGCTTGGGCTTCCTGACAGC
72 B OBD159_3885 CCCACGAGGGCAGATTTCACCTG OBD159_3887 CTCAGCAGACAGCAGAAAGGACC
73 B OBD159_3889 GTGAAAATGAAGCAGATGGCAAACTGGG OBD159_3891 GTTTACCAATCTCTGACATAGACCAACA
74 B OBD159_3893 GCAATCCCTCCAGCCCTTGTCAA OBD159_3895 TGTTGTCCTCCCAGCCTCCAGAG
75 B OBD159_3897 AAATGTGTGCCTCCCCTGACCTACA OBD159_3899 ATACGAGTGGCAGGTTAGTTCATTAT
76 B OBD159_3901 GTAACACATTCTTCAAACATAGTCCC OBD159_3903 AGAAATCACTCTCTGCCATCTCC
77 C OBD159_3325 CTCCCCATTAGTGCTTCTCCTGC OBD159_3327 GGAAAGTTCAGGGCTGGCAGTGC
78 C OBD159_3269 GCCTCCACTGATGTTAGCCTGTGACA OBD159_3271 GGTTCTTTCTTGTTTTGCTCACCACC
79 C OBD159_3177 AGTGGCTGAGGCAAGAGGATGTC OBD159_3179 GCTGAGGTTGTGTCCTGGAACAGAC
80 C OBD159_3201 CCCCTATTACATTAGTCAAATCACCT OBD159_3203 TTTCTTTGCTCTCCTCTCTCAGCCTG
81 C OBD159_3357 GCCATTTCTCACCCGCTCAGTAG OBD159_3359 GACTGCTGGGCTGGAAAATCCCC
82 C OBD159_3637 CCTCCTGTCCCTCCTTCCTTTCTC OBD159_3639 GGTGTGGATGTCTGAGGTGGAAG
83 C OBD159_3369 TATGTTGTTGCCCTTGATACGGTAGC OBD159_3371 GGGTCTCCAGGTCCCATTCTTTTCCT
84 C OBD159_3485 CGCCTGTTGTCCCAGCACTGTAGATA OBD159_3487 GGTATCAGGCTATTTCCTTCTGCTAC
85 C OBD159_3449 CGCCTGGTCCACTGTGAAGTTGG OBD159_3451 TACACCCAAACACAGCGACTGCG
86 C OBD159_3337 GCCTATGAAGAGCCTAAACATTGGTG OBD159_3339 CCACAGAACTGATGCCAAGAACTGGG
87 C OBD159_3197 TAGTTCAAGTTCTTCTCAAAAGCCCC OBD159_3199 GTTACCGCCTTTATGGCACAGCACCA
88 C OBD159_3265 ACAAGGAGCCAAAGGTAAACAGACTG OBD159_3267 GAGACCATAGGCAAGCAGGTTCTGTG
89 C OBD159_3185 GCTTATTTCCTGAACGCACTTGCCTA OBD159_3187 GGATAACTCCAGGACTAAGGATGC
90 C OBD159_3241 AGCATCATACATTTCCCGCAGTTTGC OBD159_3243 TGAGACCGATAAAGGTAGAGGGTTTT
91 C OBD159_3365 TTGTGCTACATTTTCCTCCCTAAGAG OBD159_3367 CCCTCGGTTCCCTCACTCTTTTCTGT
92 C OBD159_3309 GTGCGGGATTCAGACCTTCAGCA OBD159_3311 ACTACCTGGAAAGGGAGACCCCG
93 C OBD159_3389 GCTGCTGGGAGGGTCTTACACTG OBD159_3391 CAGGGCTTGCTTTGGACAGGAGT
94 C OBD159_3233 GGTGCGGGATTCAGACCTTCAGC OBD159_3235 GCCTCACAAAAGCGGCAGGACAT
95 C OBD159_3245 CCTCCTGTCACTGCTCCTGAAAC OBD159_3247 GTGAGGCTTGCTGATTGGGCAGTC
96 C OBD159_3313 GGGTCACTTCCCCTCATTTTCCCC OBD159_3315 TTGGAGCAAGAAAGGGAGGCACG
97 C OBD159_3353 CATTACAAAGCAGTTGGGAAGAAGGG OBD159_3355 GGAGTCCACTGAGGCAGAGTAGAGAA
98 C OBD159_3257 CGTATGGGTTTGTTTGTGTGTGGGTT OBD159_3259 CAGTCATCTCATTCACACATTGCCTG
99 C OBD159_3161 GATTAGAAACACAAGAGACCAGAGGC OBD159_3163 AGCAGGGAGAGCATTAGACCATTGTC
100 C OBD159_3301 AGCACAGAGGCAGAGGGAGGAAG OBD159_3303 GTGGTTGGTGGACCTGGCAAAAG
101 C OBD159_3341 GGTGCGGGATTCAGACCTTCAGC OBD159_3343 GCAGGCACAATCCTTCCCAATGC
102 C OBD159_3237 GGTGCGGGATTCAGACCTTCAGC OBD159_3239 CAAGTGCTTCCTGAGGTGACTGC
表8.2h
編號 群組 探針 基因座 Probe_Count_Total
103 C ORF14_7_106136911_106139119_106155635_106157326_RR N/A N/A
104 C ORF154_20_8536736_8541378_8617739_8619868_RR N/A N/A
105 C ORF13_4_143433910_143437405_143448534_143453407_FF N/A N/A
106 C ORF174_6_27413034_27418482_27440151_27442553_FR N/A N/A
107 C ORF141_7_10116043_10123567_10183118_10197721_RF N/A N/A
108 C ORF16_14_25540524_25542178_25611611_25628347_RR N/A N/A
109 C ORF13_18_11120542_11126658_11179423_11180892_FF N/A N/A
110 C ORF11_4_125340607_125343598_125382298_125392915_FF N/A N/A
111 C ORF184_5_58015461_58023944_58085103_58086932_RF N/A N/A
112 C ORF118_2_227923203_227932124_227972103_227976215_FF N/A N/A
113 C ORF19_12_4449560_4457960_4518174_4519818_FR N/A N/A
114 C ORF112_9_105368835_105370455_105414393_105415801_FF N/A N/A
115 C ORF116_2_209634852_209638927_209684451_209692640_FF N/A N/A
116 C ORF172_9_8138555_8143223_8167171_8181381_FF N/A N/A
117 C ORF13_2_106158642_106160954_106232485_106234911_FR N/A N/A
118 C ORF128_5_42377041_42385919_42438799_42441730_FR N/A N/A
119 C ORF12_16_27236516_27245702_27324505_27326522_FF N/A N/A
120 C ORF186_1_111517187_111519912_111535220_111538688_RR N/A N/A
121 C ORF102_9_8811961_8818994_8886566_8895563_FF N/A N/A
122 C ORF194_6_155219095_155222285_155266642_155272264_RF N/A N/A
123 C ORF153_2_38148629_38155476_38179203_38180978_RF N/A N/A
124 C ORF176_2_174770802_174773897_174874107_174881547_FF N/A N/A
125 C ORF12_13_27276527_27282043_27312084_27318228_RR N/A N/A
126 C ORF16_7_111035039_111042953_111093152_111098806_RR N/A N/A
127 C ORF14_2_106158642_106160954_106232485_106234911_RR N/A N/A
128 C ORF193_7_110903831_110929891_110971827_110980437_FR N/A N/A
129 C ORF1_5_176613477_176617551_176680676_176682882_RF N/A N/A
130 C ORF18_7_106136911_106139119_106183992_106185753_RR N/A N/A
131 C ORF142_20_8536736_8541378_8588020_8590421_FR N/A N/A
132 C ORF175_4_20552692_20562244_20609595_20612048_FF N/A N/A
133 C ORF130_20_21483562_21487561_21556998_21560005_FF N/A N/A
134 C ORF13_20_10323987_10325423_10353508_10357454_RR N/A N/A
135 C ORF12_7_22368712_22370568_22401546_22402661_RR N/A N/A
136 C ORF192_5_79070482_79071656_79131598_79144935_RR N/A N/A
137 C ORF145_1_229817736_229820596_229849427_229855718_FF N/A N/A
138 C ORF162_6_61648546_61654260_61702551_61716000_RF N/A N/A
139 B ORF194_11_44526701_44529279_44604674_44605773_RF N/A N/A
140 B ORF16_3_46479747_46488239_46559199_46566649_FR N/A N/A
141 B ORF184_2_209614911_209618135_209684451_209692640_RF N/A N/A
142 B ORF13_7_106136911_106139119_106190436_106195694_RR N/A N/A
143 B ORF155_1_111472532_111477653_111535220_111538688_RR N/A N/A
144 B ORF128_6_68648483_68653667_68703842_68708467_FF N/A N/A
145 B ORF127_15_88349285_88356402_88400169_88403416_FF N/A N/A
146 B ORF11_5_176613477_176617551_176666420_176668727_RF N/A N/A
147 B ORF193_14_100323802_100329446_100399165_100403839_RR N/A N/A
148 B ORF11_17_1986444_1988214_2093493_2096428_RR N/A N/A
149 B ORF18_4_151954708_151965424_152011202_152016397_FF N/A N/A
150 B ORF199_5_124405371_124409805_124446457_124450050_RR N/A N/A
151 B ORF108_11_120066945_120072959_120088100_120090309_RF N/A N/A
152 B ORF16_7_106136911_106139119_106195694_106199610_RR N/A N/A
153 B ORF1_6_163982666_163985777_164038165_164043521_FR N/A N/A
表8.3a
編號 群組 Probe_Count_Sig HyperG_Stats FDR_HyperG Percent_Sig logFC AveExpr
103 C N/A N/A N/A N/A -0.640045509 -0.640045509
104 C N/A N/A N/A N/A -0.636079084 -0.636079084
105 C N/A N/A N/A N/A -0.633852595 -0.633852595
106 C N/A N/A N/A N/A -0.626929583 -0.626929583
107 C N/A N/A N/A N/A -0.624063051 -0.624063051
108 C N/A N/A N/A N/A -0.623948872 -0.623948872
109 C N/A N/A N/A N/A -0.623902455 -0.623902455
110 C N/A N/A N/A N/A -0.622920918 -0.622920918
111 C N/A N/A N/A N/A -0.621282612 -0.621282612
112 C N/A N/A N/A N/A -0.620914449 -0.620914449
113 C N/A N/A N/A N/A -0.618133467 -0.618133467
114 C N/A N/A N/A N/A -0.616696521 -0.616696521
115 C N/A N/A N/A N/A -0.614015867 -0.614015867
116 C N/A N/A N/A N/A -0.612905757 -0.612905757
117 C N/A N/A N/A N/A -0.611470158 -0.611470158
118 C N/A N/A N/A N/A -0.610708394 -0.610708394
119 C N/A N/A N/A N/A -0.609828418 -0.609828418
120 C N/A N/A N/A N/A -0.607675757 -0.607675757
121 C N/A N/A N/A N/A -0.607005611 -0.607005611
122 C N/A N/A N/A N/A -0.606425108 -0.606425108
123 C N/A N/A N/A N/A -0.605617232 -0.605617232
124 C N/A N/A N/A N/A -0.604838546 -0.604838546
125 C N/A N/A N/A N/A -0.60275613 -0.60275613
126 C N/A N/A N/A N/A -0.599633345 -0.599633345
127 C N/A N/A N/A N/A -0.599240184 -0.599240184
128 C N/A N/A N/A N/A -0.598938813 -0.598938813
129 C N/A N/A N/A N/A -0.598849944 -0.598849944
130 C N/A N/A N/A N/A -0.59571577 -0.59571577
131 C N/A N/A N/A N/A -0.594864882 -0.594864882
132 C N/A N/A N/A N/A -0.594826085 -0.594826085
133 C N/A N/A N/A N/A -0.591728575 -0.591728575
134 C N/A N/A N/A N/A -0.59170328 -0.59170328
135 C N/A N/A N/A N/A -0.590934742 -0.590934742
136 C N/A N/A N/A N/A -0.587372199 -0.587372199
137 C N/A N/A N/A N/A -0.587330628 -0.587330628
138 C N/A N/A N/A N/A -0.585923665 -0.585923665
139 B N/A N/A N/A N/A -0.58297402 -0.58297402
140 B N/A N/A N/A N/A -0.58250559 -0.58250559
141 B N/A N/A N/A N/A -0.581621332 -0.581621332
142 B N/A N/A N/A N/A -0.581020972 -0.581020972
143 B N/A N/A N/A N/A -0.580266284 -0.580266284
144 B N/A N/A N/A N/A -0.57890323 -0.57890323
145 B N/A N/A N/A N/A -0.57811455 -0.57811455
146 B N/A N/A N/A N/A -0.577795827 -0.577795827
147 B N/A N/A N/A N/A -0.577359947 -0.577359947
148 B N/A N/A N/A N/A -0.576844081 -0.576844081
149 B N/A N/A N/A N/A -0.576623587 -0.576623587
150 B N/A N/A N/A N/A -0.576363817 -0.576363817
151 B N/A N/A N/A N/A -0.575891957 -0.575891957
152 B N/A N/A N/A N/A -0.575472897 -0.575472897
153 B N/A N/A N/A N/A -0.575114016 -0.575114016
表8.3b
編號 群組 t P值 adj.P.Val B FC
103 C -3.814902652 0.002468744 0.008765033 -2.033185207 0.641692706
104 C -6.16266968 0.0000488 0.000501213 1.997735418 0.64345935
105 C -8.766625485 0.00000147 0.0000511 5.60909361 0.644453158
106 C -6.87730155 0.0000172 0.000249494 3.077788278 0.647553105
107 C -3.712475281 0.002974803 0.010131836 -2.222055083 0.648841026
108 C -8.345138114 0.00000246 0.0000702 5.082406652 0.648892379
109 C -8.905181362 0.00000125 0.0000458 5.777814484 0.648913257
110 C -6.306530562 0.0000394 0.000431581 2.220905953 0.649354895
111 C -5.229436725 0.00021248 0.001418673 0.479128889 0.650092713
112 C -4.984094922 0.000319131 0.001915337 0.059957021 0.650258632
113 C -9.214496212 0.000000871 0.0000367 6.146852964 0.651513299
114 C -4.395680482 0.000875115 0.00404284 -0.976058903 0.652162539
115 C -5.830333035 0.0000813 0.000715489 1.470987158 0.653375441
116 C -11.35869544 0.0000000903 0.00000925 8.444373849 0.653878387
117 C -18.24832932 0.000000000415 0.000000642 13.64976188 0.654529373
118 C -5.825733101 0.0000819 0.000718842 1.463586606 0.654875065
119 C -6.877520094 0.0000172 0.000249458 3.078107745 0.65527463
120 C -12.30291776 0.0000000372 0.00000569 9.33032888 0.656253102
121 C -3.834281763 0.002383418 0.008532895 -1.997511072 0.656558009
122 C -8.597686222 0.00000180 0.0000578 5.400446867 0.656822244
123 C -12.45917871 0.0000000323 0.00000530 9.47046222 0.657190153
124 C -8.630824333 0.00000173 0.0000565 5.441630153 0.657544963
125 C -6.266523248 0.0000418 0.000448841 2.159136079 0.658494762
126 C -4.358035947 0.000934874 0.004228836 -1.043673578 0.659921651
127 C -14.67403678 0.00000000509 0.00000207 11.28238735 0.660101516
128 C -4.543549457 0.000676271 0.0033356 -0.711917511 0.660239422
129 C -3.785290802 0.002605235 0.00914021 -2.087735118 0.660280093
130 C -3.89750471 0.002125545 0.00784286 -1.881277291 0.661716074
131 C -7.818730494 0.00000480 0.000107796 4.394984269 0.662106463
132 C -7.69396267 0.00000564 0.000119627 4.227033097 0.662124269
133 C -5.234115134 0.000210856 0.00141049 0.487043936 0.663547397
134 C -9.447799994 0.000000667 0.0000310 6.418432274 0.663559031
135 C -6.338534374 0.0000375 0.000417454 2.270156333 0.66391261
136 C -6.484220917 0.0000303 0.000361081 2.492533035 0.665554079
137 C -6.445699918 0.0000320 0.000375266 2.43402391 0.665573257
138 C -5.544376271 0.00012762 0.000983373 1.005255977 0.666222662
139 B -11.62179099 0.0000000701 0.00000803 8.698220728 0.667586174
140 B -8.387351643 0.00000233 0.0000681 5.136086408 0.667802968
141 B -8.327361769 0.00000251 0.0000712 5.059738807 0.668212404
142 B -3.78437398 0.002609582 0.00915144 -2.089424776 0.66849053
143 B -11.91770856 0.0000000530 0.00000684 8.977187098 0.668840316
144 B -8.663189614 0.00000167 0.0000552 5.481731704 0.669472532
145 B -7.289339635 0.00000970 0.00017077 3.668636027 0.669838614
146 B -5.079540206 0.000272154 0.001702011 0.223974519 0.669986612
147 B -7.53374465 0.00000698 0.000137076 4.008459114 0.670189065
148 B -5.835924402 0.0000806 0.000711241 1.479978735 0.670428749
149 B -10.16540863 0.000000304 0.0000191 7.219100586 0.670531221
150 B -8.15126985 0.00000313 0.0000818 4.833156506 0.670651967
151 B -4.291941295 0.001050276 0.0046232 -1.16273352 0.670871352
152 B -4.027542945 0.001681609 0.006570265 -1.64302313 0.671066248
153 B -3.202067087 0.007616825 0.02095053 -3.166725894 0.671233202
表8.3c
編號 群組 FC_1 LS 偵測到之環
103 C -1.558378317 -1 重度自閉症
104 C -1.554099726 -1 重度自閉症
105 C -1.551703158 -1 重度自閉症
106 C -1.54427489 -1 重度自閉症
107 C -1.541209572 -1 重度自閉症
108 C -1.541087601 -1 重度自閉症
109 C -1.541038019 -1 重度自閉症
110 C -1.539989931 -1 重度自閉症
111 C -1.53824213 -1 重度自閉症
112 C -1.537849635 -1 重度自閉症
113 C -1.534888085 -1 重度自閉症
114 C -1.533360075 -1 重度自閉症
115 C -1.530513603 -1 重度自閉症
116 C -1.529336372 -1 重度自閉症
117 C -1.527815315 -1 重度自閉症
118 C -1.527008819 -1 重度自閉症
119 C -1.526077699 -1 重度自閉症
120 C -1.52380232 -1 重度自閉症
121 C -1.523094664 -1 重度自閉症
122 C -1.522481933 -1 重度自閉症
123 C -1.521629617 -1 重度自閉症
124 C -1.520808548 -1 重度自閉症
125 C -1.518614965 -1 重度自閉症
126 C -1.515331402 -1 重度自閉症
127 C -1.514918502 -1 重度自閉症
128 C -1.514602078 -1 重度自閉症
129 C -1.514508782 -1 重度自閉症
130 C -1.511222168 -1 重度自閉症
131 C -1.510331126 -1 重度自閉症
132 C -1.510290511 -1 重度自閉症
133 C -1.50705135 -1 重度自閉症
134 C -1.507024927 -1 重度自閉症
135 C -1.506222333 -1 重度自閉症
136 C -1.502507507 -1 重度自閉症
137 C -1.502464213 -1 重度自閉症
138 C -1.500999676 -1 重度自閉症
139 B -1.497933959 -1 重度自閉症
140 B -1.497447673 -1 重度自閉症
141 B -1.496530137 -1 重度自閉症
142 B -1.495907503 -1 重度自閉症
143 B -1.495125184 -1 重度自閉症
144 B -1.493713262 -1 重度自閉症
145 B -1.492896914 -1 重度自閉症
146 B -1.492567137 -1 重度自閉症
147 B -1.492116258 -1 重度自閉症
148 B -1.491582815 -1 重度自閉症
149 B -1.491354867 -1 重度自閉症
150 B -1.491086359 -1 重度自閉症
151 B -1.490598752 -1 重度自閉症
152 B -1.490165841 -1 重度自閉症
153 B -1.489795197 -1 重度自閉症
表8.3d
      探針序列 探針位置
編號 群組 60 mer Chr
103 C CTCACCACCTCCTAGCTATGACCCTTGGTCGATTCTCAATGTCTACGTGGACTAACTCAT 7
104 C TATGGTAAAATGGATTCTCTCTCAGTTCTCGAAGTGGAATTGTGAATCTTCCAATCGTCT 20
105 C GGAGTTGGTTAACTCTGTATCACGTATTTCGAGTTCTTCTTCATCTTCATTACCTTTTTT 4
106 C TCAATTCATTGATTAGGTAAATTTGTATTCGATAAAGTGGATGAACTGATTTTTAGCTAA 6
107 C TGGTTTTCCCTTCCTTTGTTACTTCACTTCGAAAGATGTTGAGTCTATCTGTAACTCAGA 7
108 C TCACATATTCATCTTCTCTCTCTTGCTATCGAATCTGATACTCTCTGCCTTTGAACTGGG 14
109 C ATATTTTTTTTTTTTTGTATTCCCAGAATCGACTTCTTCTGTTAGATGCTTGAGATGGAT 18
110 C TTTTGAACACATTTTTAAAACTCTGAGTTCGAGGGCACTGATTTTTCCAGAGTAGTGGAG 4
111 C CAAATATCCTAATAAACAAATTCCTGTGTCGATTCCTTTGTTTTCTGCATATTGGGACAC 5
112 C TCTATATAAGAAATTCGTAGGATGAATATCGAATGAAACTAACAGAGGAAGAAAAACATT 2
113 C AATCACATACTAACATCTCTCATGAAAATCGATGATTTCTTTTATGCTTACAGAAGTCCA 12
114 C CCTTTTAAAAGGCTAAATTTCTGGACATTCGAAGGACAATATTCTTCAAGTATATATTGT 9
115 C TAAGATACTAGAAACCAACATAAATTAATCGAGGCTGTAAGTAAATCTGAAGTAATCGGG 2
116 C CCCCACTCTGCCCTCAATTGTGGTTCATTCGATAAATATGTGTTGAATCTAAGAGAGTGT 9
117 C AAAAAACTATCTTATACTCCTCACTTCTTCGACTCGCTGACACCACCCCACCCCACCCCT 2
118 C ATGCTAAATTATGTAAAATGGAATATGTTCGAGATGACTGCAGTCTTCCACCAACAGCTT 5
119 C CTGTCAATTCTGTATGTTGAGAAATTCATCGAATAATTTTTAAATTTTTGTAGAGATGGG 16
120 C GGACTCAGTCTCTCCAGGAGAGACTTTATCGAAATGTATCCACCCACCCCACCTCTAAAC 1
121 C CACTCTAGTCCACTACTAGTTGCAATGTTCGATTTTATTTATTCATAGTGAGTTGAAGTC 9
122 C AAGAATAGGTCTTTCGGTATTATTTAGTTCGAAGTTAGTGTCAGTGGTCAACTTCTCCCG 6
123 C CTAGATTCCCAGAAGAAAGATTACTGATTCGATCATTGCTCAATGACCAAGTCACAAAGT 2
124 C TTGCATTGGTGCAAAAAATGCAATCAAATCGAGCCTACTATATATATTTAGCTTTGACTT 2
125 C TATTATAATTGACTTATTTTTCCATTATTCGAAGTCCATAGTTGACATTATAATTCAGTC 13
126 C TGTTTTCTTTTAACATCCTATTATTGACTCGATTTTCTCTCTGTAAGATGAACAAGTTTA 7
127 C ACCTCGGCTTAGGAATGTGGCTTCAATCTCGACTCGCTGACACCACCCCACCCCACCCCT 2
128 C TCATGAAATGATTGAGTTGTGAATTTCATCGAGATATGCATTATTAATGTTTAAACTGTG 7
129 C ATGTAATCATCATCATCATACTTTATAATCGATATCATCCTATACAATGCTTAGCTCTCA 5
130 C CTCACCACCTCCTAGCTATGACCCTTGGTCGATTCAATTGCTAGGCAGATGTCCTTGTAG 7
131 C GATGAGTAACATAGTAGAAAAAAATACTTCGAAACTGTCACTCTGGTGTTGAGATAAATA 20
132 C CTTATCTTTATTTGCTGTCTTTACATCTTCGAAAGATTTAATGAAGTGGATTCTAATGAA 4
133 C TTATCTTTATAAATCATACCATATAGCTTCGACTCCAAATGCAGAATGTAACTCATGAGC 20
134 C TCTTCTAAAGACAAGTCCCAGTTTAAGATCGATGAATTCAAGGAAATATATTCAGGTCAC 20
135 C TGAATTTATTTCATGTTCTCTTCTAATGTCGAATTACAGTCTCAGGCTTGACAAAACCTA 7
136 C CACTCCTTCATCCCACCCCCACACATACTCGAAATTAAATGTGTGATCCATCCTAGTATT 5
137 C GATTTCAATGTAGATCTTCAAACTCTCATCGATTTTTCAATGTTTGTGACAAAACCGGTT 1
138 C TAAAATGGCTACATTTTTTTTTCCATTCTCGAATTTAGAGATGAACACACGTTCTGCCTC 6
139 B GAACTCTCAGAGTGGTTGCAAAGATTATTCGACCCGCTTTCCTCCCCGCCCCCTCATCCG 11
140 B CTGGGTACCCTTATGTAAAATAAATTTATCGACTTAAAAGTCTCCATAAAGGAACGCTAC 3
141 B CCCGATTACTTCAGATTTACTTACAGCCTCGATGAACTTCCTCTGCTTCTAGAGCTTTTA 2
142 B CTCACCACCTCCTAGCTATGACCCTTGGTCGATAAGAAAGACTGTATTCTCAAGGAATTC 7
143 B AAGGAGTGCACATTTCCACTTAGAGAACTCGAAATGTATCCACCCACCCCACCTCTAAAC 1
144 B AGACTATTCTTTCAACATTTAAAGATACTCGAGGACAGGGAATAGAAATGCTTTCAAAGA 6
145 B ATGAGTCAAGAATTCAGAAAGAGTGCAATCGACCTACATTTTCTTTGTCTTTGTAATGGA 15
146 B TCAATTTATTGAGTCTAATTTACATACATCGATATCATCCTATACAATGCTTAGCTCTCA 5
147 B CATCTTCCCTACCCATCTCCCCACCCTCTCGAATTTAGACTGCTTACCACATTGATGTTT 14
148 B TTATCTCAAGATCTTTAACTTAATTACATCGATAATTGAGCAGCTGGCATTTTTTTTTCC 17
149 B TTCCCCACTGCCTCCCATCCTTTATCTCTCGAAGTAGTCCTTGTACCTACCATGATCATC 4
150 B ATATTCTTTCAATATTTGTACATTTATATCGAAGCAGAGATGTCTTGCAGTCAGAGTCAA 5
151 B CACAGAATAGACTCTCAGTAAATAACTATCGAATTTAATCTGCGTCTGATATGCTGGCAG 11
152 B CTCACCACCTCCTAGCTATGACCCTTGGTCGACAAGAGCCTCCTGACAGGTCTGCCTGCC 7
153 B TCAATCAGGAATCACTGTAAATATTGACTCGAGGTGTAGAGAAAACCCTGGAAGGGGGGT 6
表8.3e
      探針位置 4 kb 序列位置
編號 群組 起點 1 終點 1 起點 2 終點 2 Chr 起點 1
103 C 106136913 106136942 106155637 106155666 7 106136913
104 C 8536738 8536767 8617741 8617770 20 8536738
105 C 143437374 143437403 143453376 143453405 4 143433404
106 C 27418451 27418480 27440153 27440182 6 27414481
107 C 10116045 10116074 10197690 10197719 7 10116045
108 C 25540526 25540555 25611613 25611642 14 25540526
109 C 11126627 11126656 11180861 11180890 18 11122657
110 C 125343567 125343596 125392884 125392913 4 125339597
111 C 58015463 58015492 58086901 58086930 5 58015463
112 C 227932093 227932122 227976184 227976213 2 227928123
113 C 4457929 4457958 4518176 4518205 12 4453959
114 C 105370424 105370453 105415770 105415799 9 105366454
115 C 209638896 209638925 209692609 209692638 2 209634926
116 C 8143192 8143221 8181350 8181379 9 8139222
117 C 106160923 106160952 106232487 106232516 2 106156953
118 C 42385888 42385917 42438801 42438830 5 42381918
119 C 27245671 27245700 27326491 27326520 16 27241701
120 C 111517189 111517218 111535222 111535251 1 111517189
121 C 8818963 8818992 8895532 8895561 9 8814993
122 C 155219097 155219126 155272233 155272262 6 155219097
123 C 38148631 38148660 38180947 38180976 2 38148631
124 C 174773866 174773895 174881516 174881545 2 174769896
125 C 27276529 27276558 27312086 27312115 13 27276529
126 C 111035041 111035070 111093154 111093183 7 111035041
127 C 106158644 106158673 106232487 106232516 2 106158644
128 C 110929860 110929889 110971829 110971858 7 110925890
129 C 176613479 176613508 176682851 176682880 5 176613479
130 C 106136913 106136942 106183994 106184023 7 106136913
131 C 8541347 8541376 8588022 8588051 20 8537377
132 C 20562213 20562242 20612017 20612046 4 20558243
133 C 21487530 21487559 21559974 21560003 20 21483560
134 C 10323989 10324018 10353510 10353539 20 10323989
135 C 22368714 22368743 22401548 22401577 7 22368714
136 C 79070484 79070513 79131600 79131629 5 79070484
137 C 229820565 229820594 229855687 229855716 1 229816595
138 C 61648548 61648577 61715969 61715998 6 61648548
139 B 44526703 44526732 44605742 44605771 11 44526703
140 B 46488208 46488237 46559201 46559230 3 46484238
141 B 209614913 209614942 209692609 209692638 2 209614913
142 B 106136913 106136942 106190438 106190467 7 106136913
143 B 111472534 111472563 111535222 111535251 1 111472534
144 B 68653636 68653665 68708436 68708465 6 68649666
145 B 88356371 88356400 88403385 88403414 15 88352401
146 B 176613479 176613508 176668696 176668725 5 176613479
147 B 100323804 100323833 100399167 100399196 14 100323804
148 B 1986446 1986475 2093495 2093524 17 1986446
149 B 151965393 151965422 152016366 152016395 4 151961423
150 B 124405373 124405402 124446459 124446488 5 124405373
151 B 120066947 120066976 120090278 120090307 11 120066947
152 B 106136913 106136942 106195696 106195725 7 106136913
153 B 163985746 163985775 164038167 164038196 6 163981776
表8.3f
      4 kb 序列位置   
編號 群組 終點 1 起點 2 終點 2 探針
103 C 106140912 106155637 106159636 ORF14_7_106136911_106139119_106155635_106157326_RR
104 C 8540737 8617741 8621740 ORF154_20_8536736_8541378_8617739_8619868_RR
105 C 143437403 143449406 143453405 ORF13_4_143433910_143437405_143448534_143453407_FF
106 C 27418480 27440153 27444152 ORF174_6_27413034_27418482_27440151_27442553_FR
107 C 10120044 10193720 10197719 ORF141_7_10116043_10123567_10183118_10197721_RF
108 C 25544525 25611613 25615612 ORF16_14_25540524_25542178_25611611_25628347_RR
109 C 11126656 11176891 11180890 ORF13_18_11120542_11126658_11179423_11180892_FF
110 C 125343596 125388914 125392913 ORF11_4_125340607_125343598_125382298_125392915_FF
111 C 58019462 58082931 58086930 ORF184_5_58015461_58023944_58085103_58086932_RF
112 C 227932122 227972214 227976213 ORF118_2_227923203_227932124_227972103_227976215_FF
113 C 4457958 4518176 4522175 ORF19_12_4449560_4457960_4518174_4519818_FR
114 C 105370453 105411800 105415799 ORF112_9_105368835_105370455_105414393_105415801_FF
115 C 209638925 209688639 209692638 ORF116_2_209634852_209638927_209684451_209692640_FF
116 C 8143221 8177380 8181379 ORF172_9_8138555_8143223_8167171_8181381_FF
117 C 106160952 106232487 106236486 ORF13_2_106158642_106160954_106232485_106234911_FR
118 C 42385917 42438801 42442800 ORF128_5_42377041_42385919_42438799_42441730_FR
119 C 27245700 27322521 27326520 ORF12_16_27236516_27245702_27324505_27326522_FF
120 C 111521188 111535222 111539221 ORF186_1_111517187_111519912_111535220_111538688_RR
121 C 8818992 8891562 8895561 ORF102_9_8811961_8818994_8886566_8895563_FF
122 C 155223096 155268263 155272262 ORF194_6_155219095_155222285_155266642_155272264_RF
123 C 38152630 38176977 38180976 ORF153_2_38148629_38155476_38179203_38180978_RF
124 C 174773895 174877546 174881545 ORF176_2_174770802_174773897_174874107_174881547_FF
125 C 27280528 27312086 27316085 ORF12_13_27276527_27282043_27312084_27318228_RR
126 C 111039040 111093154 111097153 ORF16_7_111035039_111042953_111093152_111098806_RR
127 C 106162643 106232487 106236486 ORF14_2_106158642_106160954_106232485_106234911_RR
128 C 110929889 110971829 110975828 ORF193_7_110903831_110929891_110971827_110980437_FR
129 C 176617478 176678881 176682880 ORF1_5_176613477_176617551_176680676_176682882_RF
130 C 106140912 106183994 106187993 ORF18_7_106136911_106139119_106183992_106185753_RR
131 C 8541376 8588022 8592021 ORF142_20_8536736_8541378_8588020_8590421_FR
132 C 20562242 20608047 20612046 ORF175_4_20552692_20562244_20609595_20612048_FF
133 C 21487559 21556004 21560003 ORF130_20_21483562_21487561_21556998_21560005_FF
134 C 10327988 10353510 10357509 ORF13_20_10323987_10325423_10353508_10357454_RR
135 C 22372713 22401548 22405547 ORF12_7_22368712_22370568_22401546_22402661_RR
136 C 79074483 79131600 79135599 ORF192_5_79070482_79071656_79131598_79144935_RR
137 C 229820594 229851717 229855716 ORF145_1_229817736_229820596_229849427_229855718_FF
138 C 61652547 61711999 61715998 ORF162_6_61648546_61654260_61702551_61716000_RF
139 B 44530702 44601772 44605771 ORF194_11_44526701_44529279_44604674_44605773_RF
140 B 46488237 46559201 46563200 ORF16_3_46479747_46488239_46559199_46566649_FR
141 B 209618912 209688639 209692638 ORF184_2_209614911_209618135_209684451_209692640_RF
142 B 106140912 106190438 106194437 ORF13_7_106136911_106139119_106190436_106195694_RR
143 B 111476533 111535222 111539221 ORF155_1_111472532_111477653_111535220_111538688_RR
144 B 68653665 68704466 68708465 ORF128_6_68648483_68653667_68703842_68708467_FF
145 B 88356400 88399415 88403414 ORF127_15_88349285_88356402_88400169_88403416_FF
146 B 176617478 176664726 176668725 ORF11_5_176613477_176617551_176666420_176668727_RF
147 B 100327803 100399167 100403166 ORF193_14_100323802_100329446_100399165_100403839_RR
148 B 1990445 2093495 2097494 ORF11_17_1986444_1988214_2093493_2096428_RR
149 B 151965422 152012396 152016395 ORF18_4_151954708_151965424_152011202_152016397_FF
150 B 124409372 124446459 124450458 ORF199_5_124405371_124409805_124446457_124450050_RR
151 B 120070946 120086308 120090307 ORF108_11_120066945_120072959_120088100_120090309_RF
152 B 106140912 106195696 106199695 ORF16_7_106136911_106139119_106195694_106199610_RR
153 B 163985775 164038167 164042166 ORF1_6_163982666_163985777_164038165_164043521_FR
表8.3g
編號 群組 PCR- 引子 1_ID PCR_ 引子 1 PCR- 引子 2_ID PCR_ 引子 2
103 C OBD159_3305 AAGAGCACGGACACCAAACAGGTCTA OBD159_3307 CTCAGCCTTAGGAGGATGTGACTATC
104 C OBD159_3277 GCTGGCTTGGGATTGTGTTGAACCAC OBD159_3279 TTTTCTCAAACGAGTCCCACCCAATA
105 C OBD159_3193 ACTAAGAAGTCAGGGAAGGTAAGCCC OBD159_3195 CTAATACGAAAACCAAGGAATACCCT
106 C OBD159_3261 GCCCTGGATAGGACCTGGCAGAT OBD159_3263 CTGACTCTCTTGGGTGCTTGAGC
107 C OBD159_3181 CCTGAGTCCCCAAAGTCCATTAGTCC OBD159_3183 CTCATAGAAAAGGGTAGAAAGCAGAG
108 C OBD159_3321 TGTGTGTAAGTTCCCTTCCCCGACTA OBD159_3323 GAAGGACAAAGAGCAGATGGAACAAA
109 C OBD159_3349 CCTCACACAGTCCTCTTCCCACC OBD159_3351 GAGTCAGCCTATGGGACACAGCA
110 C OBD159_3169 TAGAACCCATAGCACCAAGTCCAT OBD159_3171 GTGTCTTAGGCACATCATTCAGC
111 C OBD159_3157 TTTGGTGTATGGTGTAGTAACCTCAC OBD159_3159 CTCTACCATTTTCTGCTTCCTCCGCC
112 C OBD159_3217 CCTTCTTCTCCTTGCCTTTCCTCTGG OBD159_3219 GGAGTTCAACAAAGTGGTGGGAATCT
113 C OBD159_3213 CCAAATCCAGACAAGGACATTCAAGA OBD159_3215 CCCAGGAGCCCAGTTGAAGACCAT
114 C OBD159_3361 TCCTACCTTGGGAGTGAGTGAAAGAG OBD159_3363 GACACCTGCTGGTTGAGAGTGACAAT
115 C OBD159_3189 GTGTAAGCAGTTTATGGTCAGAGTCT OBD159_3191 GCTTATTTCCTGAACGCACTTGCCTA
116 C OBD159_3221 TTTACAGCCCCACCAGCAACACAGGA OBD159_3223 GAGAGAAGTGAGAGAAAGTTGGGACT
117 C OBD159_3289 GCAGTGACGGGCATAAGATGGAC OBD159_3291 TGTGCTCTCCCTCCCCAATGTGC
118 C OBD159_3165 TTGGCAAAACAACTTCCCACTGACCT OBD159_3167 GGTGGCTCTGGCTGATGGTCTTTCAT
119 C OBD159_3333 GCCAGCAAGAGCCAGAGACACAA OBD159_3335 TGAGGAGATGGCTGGACACGGCA
120 C OBD159_3373 GTCACCCTGTATTGCCATAGCAGCAT OBD159_3375 GGCTCTGAACCTCTCCTTGGAACAAT
121 C OBD159_3205 AACTAACCAGGAAAACGACATAGCAC OBD159_3207 CCTTCCAAGAGGGTCTGGCATTCTC
122 C OBD159_3285 GTGAAGGCTACTGACAAAAGGTATGG OBD159_3287 CAGCCTACTCCTGCTAAAGGGAAAGG
123 C OBD159_3397 CTCTATTTGGCATCCTTTCCTTAGGC OBD159_3399 GGCAGAAATGTAAGGAGCACACCTGG
124 C OBD159_3209 AATGTCTATCTCAGCAGAGTCACAGA OBD159_3211 CTACCCCAGATGGCTGTGAGGATTAC
125 C OBD159_3317 TTAGAACTTCCATTGTGCCCTTCGCC OBD159_3319 GGAGTTATGGGAAGAGGAAGGGATGA
126 C OBD159_3173 AGCAGTTACAGTTTTGAAGCAGGGCT OBD159_3175 TGTGGCATTTGAGGCAGAGCGAGCAA
127 C OBD159_3377 ACCTCTGTTTGAGTGACCCTGGG OBD159_3379 TGTGCTCTCCCTCCCCAATGTGC
128 C OBD159_3225 GAAGTGACAGAGAAGGTGCCATTTAC OBD159_3227 CCTCTCCCCACACATACACCTAACTC
129 C OBD159_3453 AGCGAGGTCAATAACACCCAGGG OBD159_3455 CGGTGCTGGGCTTGCCATAACAC
130 C OBD159_3293 AAGAGCACGGACACCAAACAGGTCTA OBD159_3295 TGGAGTCACTTGTGTCAAAACCCTGA
131 C OBD159_3281 GCTGGTGTGCCACTAATGCTCTCC OBD159_3283 TTCATCTTCCCACCTCCCCTGGA
132 C OBD159_3249 TCATCTCCACCCCTCCACTGAAACTA OBD159_3251 GTAGTCCCTGAAGAGCAATCTCAAGG
133 C OBD159_3297 AGAAGGCTGGGTGTCCAAGCAGG OBD159_3299 CCATCTTGAGACAGCACCTCTGG
134 C OBD159_3253 AGGTCCTTGACACTCTCCCTCCG OBD159_3255 TGGGCTTGTGTTCAGGCTCTGTG
135 C OBD159_3345 CGGAGACCACCATACAATAGTGCTGC OBD159_3347 CTTGAGAGAAGTCCATCTAATAGGGC
136 C OBD159_3329 TTCTGAATGACAGGGCTGGAGCGG OBD159_3331 AGTGGGTCACGAAACAGAAGAACTCT
137 C OBD159_3273 CCCCTCTTCTCCTGGGTTTATGGG OBD159_3275 GCTTTGCTTCACAGGCTTGCCCA
138 C OBD159_3229 GTAAGTCCTTCCTACTGTGCCTTTGG OBD159_3231 CAGGATGGTTAGAATGACCGCCTTGT
139 B OBD159_3905 GCCTCTATGTGCCTGTTCCACCA OBD159_3907 TTATTGCTCCCCACACCCCACCC
140 B OBD159_3909 CTCCAGGATTCATTCCAGCCTTCC OBD159_3911 AGTTACTGTGGCTGGCTGGGCTG
141 B OBD159_3913 GCTTATTTCCTGAACGCACTTGCCTA OBD159_3915 CACCAGAGAGAGGGAAATACAGGCTG
142 B OBD159_3917 GAGCACGGACACCAAACAGGTCT OBD159_3919 AACACAGTCCACCTGCCCCTCAG
143 B OBD159_3921 GTTCCTTGCCTCACAGACTCTACCAC OBD159_3923 GAAGTTAGCACAAAAGGAACCTGGAG
144 B OBD159_3925 GGAACAGTTGTGGTGTGCTAAAACG OBD159_3927 TGGACCCTGTGCCTCCCACTGTG
145 B OBD159_3929 GAGGAGCATTCTGGTTATCTATCACC OBD159_3931 GACTGCCTGTTTTCCAGCCATTTCCC
146 B OBD159_3933 GCTTCTTCCTCTGTCCCATAGCG OBD159_3935 CGGTGCTGGGCTTGCCATAACAC
147 B OBD159_3937 ATCAGTCTTTCACCAGGAGCCCTTCC OBD159_3939 AGTTACTGCCTCAAGACACACTCAAT
148 B OBD159_3941 TGGCTTCCCTCTGTCTCCTCCTC OBD159_3943 GCCTCTCAGACTGGCTTCCAAAC
149 B OBD159_3945 GGGAGATGAATGGGTGAGGCGAT OBD159_3947 GTGCTCTTGGTCTCCTCAGCCTC
150 B OBD159_3949 ATGGATAGATGGCAGAGGAACACAGC OBD159_3951 CAAGGAGGAGAAACAGGAGAAGGTAG
151 B OBD159_3953 GGATTCCCAGATTGAAAACAGTGCCA OBD159_3955 GCGAGAGAGAAGAGAGGCATCCACAT
152 B OBD159_3957 CTCTATGTCCTCCCCACAGCCTG OBD159_3959 TTTCAGCCAAGGGTCAAGGTGGG
153 B OBD159_3961 GGAGGGAGAAAGTCAGGAGAGAG OBD159_3963 CTGCCTGCCCATAGTCACCAGCA
表8.3h
編號 群組 探針 基因座 Probe_Count_Total
154 B ORF137_6_27448356_27449458_27496333_27502209_RF N/A N/A
155 B ORF18_2_199605749_199608546_199669603_199675100_RR N/A N/A
156 B ORF197_20_59641481_59643132_59702033_59707786_RR N/A N/A
157 B ORF190_6_139979966_139988144_140005899_140012028_RF N/A N/A
158 B ORF17_7_22293458_22299215_22368712_22370568_FF N/A N/A
159 B ORF11_7_106136911_106139119_106205835_106208610_RR N/A N/A
160 B ORF12_20_38255838_38257757_38271295_38273280_RF N/A N/A
161 B ORF170_9_8138555_8143223_8162352_8167171_FF N/A N/A
162 B ORF157_10_12567857_12569357_12596194_12598368_FR N/A N/A
163 B ORF14_6_114033384_114036052_114107829_114113558_RF N/A N/A
164 B ORF11_18_21178112_21180915_21194021_21196235_RR N/A N/A
165 B ORF169_X_922098_928065_989932_992112_FF N/A N/A
166 B ORF147_6_146088385_146093865_146155392_146161780_FR N/A N/A
167 B ORF179_9_92586435_92592480_92667358_92668932_FR N/A N/A
168 D ORF148_1_229796281_229797522_229849427_229855718_FF N/A N/A
169 D ORF121_3_182183246_182185848_182234332_182242013_FR N/A N/A
170 D ORF166_7_29763050_29768509_29809501_29813015_RR N/A N/A
171 D ORF18_6_137232223_137235679_137341897_137343885_RF N/A N/A
172 D ORF147_21_30947497_30949256_30984126_30988102_RF N/A N/A
173 D ORF197_4_22994756_23003981_23065929_23067873_FR N/A N/A
174 D ORF115_9_28293258_28294446_28333777_28339631_FF N/A N/A
175 D ORF17_4_105415477_105417649_105457783_105460154_FF N/A N/A
176 D ORF125_9_28270698_28275294_28333777_28339631_RF N/A N/A
177 D ORF162_6_46989661_46997140_47060758_47069708_RF N/A N/A
178 D ORF103_18_58202022_58205094_58215328_58217936_RF N/A N/A
179 D ORF167_2_195495210_195503375_195555062_195566669_FF N/A N/A
180 D ORF118_18_11071108_11073538_11120542_11126658_RF N/A N/A
181 D ORF1_16_68414192_68421728_68462182_68469147_RF N/A N/A
182 D ORF16_2_39607186_39609982_39623225_39627003_FR N/A N/A
183 D ORF144_2_227875567_227878014_227923203_227932124_RF N/A N/A
表8.4a
編號 群組 Probe_Count_Sig HyperG_Stats FDR_HyperG Percent_Sig logFC AveExpr
154 B N/A N/A N/A N/A -0.574808854 -0.574808854
155 B N/A N/A N/A N/A -0.574456379 -0.574456379
156 B N/A N/A N/A N/A -0.574072863 -0.574072863
157 B N/A N/A N/A N/A -0.573424876 -0.573424876
158 B N/A N/A N/A N/A -0.572722674 -0.572722674
159 B N/A N/A N/A N/A -0.57025385 -0.57025385
160 B N/A N/A N/A N/A -0.570159448 -0.570159448
161 B N/A N/A N/A N/A -0.569614568 -0.569614568
162 B N/A N/A N/A N/A -0.568586595 -0.568586595
163 B N/A N/A N/A N/A -0.568433457 -0.568433457
164 B N/A N/A N/A N/A -0.566875906 -0.566875906
165 B N/A N/A N/A N/A -0.566118538 -0.566118538
166 B N/A N/A N/A N/A -0.565782344 -0.565782344
167 B N/A N/A N/A N/A -0.565725741 -0.565725741
168 D N/A N/A N/A N/A -0.964755594 -0.964755594
169 D N/A N/A N/A N/A -0.909959217 -0.909959217
170 D N/A N/A N/A N/A -0.877638416 -0.877638416
171 D N/A N/A N/A N/A -0.810473195 -0.810473195
172 D N/A N/A N/A N/A -0.808156687 -0.808156687
173 D N/A N/A N/A N/A -0.778465363 -0.778465363
174 D N/A N/A N/A N/A -0.758831154 -0.758831154
175 D N/A N/A N/A N/A -0.756728555 -0.756728555
176 D N/A N/A N/A N/A -0.754448335 -0.754448335
177 D N/A N/A N/A N/A -0.75272274 -0.75272274
178 D N/A N/A N/A N/A -0.731354707 -0.731354707
179 D N/A N/A N/A N/A -0.72169935 -0.72169935
180 D N/A N/A N/A N/A -0.713531849 -0.713531849
181 D N/A N/A N/A N/A -0.709015088 -0.709015088
182 D N/A N/A N/A N/A -0.707334239 -0.707334239
183 D N/A N/A N/A N/A -0.707018011 -0.707018011
表8.4b
編號 群組 t P值 adj.P.Val B FC
154 B -6.891641208 0.0000168 0.000246158 3.098736098 0.671375197
155 B -2.611844439 0.02274847 0.049819113 -4.243494208 0.671539246
156 B -4.61133913 0.000601458 0.003065125 -0.591631572 0.671717787
157 B -9.334337757 0.000000759 0.0000339 6.287070231 0.672019557
158 B -6.381551033 0.0000352 0.000400231 2.336127221 0.672346728
159 B -3.595523531 0.003684558 0.011925472 -2.438232364 0.673498272
160 B -8.7739789 0.00000146 0.0000508 5.61810193 0.673542344
161 B -11.58873382 0.0000000723 0.00000818 8.666630667 0.673796777
162 B -5.179850602 0.00023053 0.001508329 0.395056271 0.674277053
163 B -10.4552549 0.000000224 0.0000160 7.528399343 0.674348629
164 B -15.82649224 0.00000000214 0.00000133 12.11208444 0.675077057
165 B -4.881942371 0.000378953 0.002172424 -0.116892175 0.675431543
166 B -5.666896334 0.000105058 0.000857 1.206210626 0.675588959
167 B -17.95302616 0.000000000501 0.000000711 13.4756476 0.675615466
168 D -3.798122869 0.00254516 0.008973828 -2.064090726 0.512365204
169 D -4.467590389 0.000771749 0.003675953 -0.847309931 0.532200136
170 D -7.390325566 0.00000846 0.000155288 3.809994153 0.544257612
171 D -14.01750686 0.00000000857 0.00000267 10.77710333 0.570194807
172 D -7.948752109 0.00000405 0.0000965 4.567931437 0.571111093
173 D -7.815132055 0.00000482 0.000108145 4.39016783 0.582986603
174 D -8.336490328 0.00000249 0.0000707 5.071383935 0.590974934
175 D -12.5874418 0.0000000288 0.00000502 9.584177076 0.591836855
176 D -5.670620457 0.000104442 0.000853663 1.212285842 0.59277301
177 D -8.225011167 0.00000286 0.0000771 4.928493509 0.593482445
178 D -5.316223813 0.000184376 0.001280565 0.625473386 0.602338046
179 D -10.8736462 0.000000146 0.0000123 7.961387425 0.606382763
180 D -5.161266549 0.000237704 0.001542225 0.363462055 0.609825402
181 D -6.967290763 0.0000151 0.000229077 3.208783547 0.611737623
182 D -6.714567946 0.0000217 0.000290609 2.838087003 0.612450759
183 D -4.350938497 0.000946609 0.004268251 -1.056437739 0.612585018
表8.4c
編號 群組 FC_1 LS 偵測到之環
154 B -1.489480106 -1 重度自閉症
155 B -1.489116245 -1 重度自閉症
156 B -1.48872044 -1 重度自閉症
157 B -1.488051932 -1 重度自閉症
158 B -1.487327829 -1 重度自閉症
159 B -1.484784804 -1 重度自閉症
160 B -1.484687651 -1 重度自閉症
161 B -1.484127017 -1 重度自閉症
162 B -1.483069899 -1 重度自閉症
163 B -1.482912483 -1 重度自閉症
164 B -1.481312377 -1 重度自閉症
165 B -1.480534941 -1 重度自閉症
166 B -1.480189969 -1 重度自閉症
167 B -1.480131896 -1 重度自閉症
168 D -1.951732852 -1 重度自閉症
169 D -1.878992381 -1 重度自閉症
170 D -1.837365209 -1 重度自閉症
171 D -1.753786579 -1 重度自閉症
172 D -1.750972817 -1 重度自閉症
173 D -1.715305282 -1 重度自閉症
174 D -1.692119144 -1 重度自閉症
175 D -1.689654828 -1 重度自閉症
176 D -1.686986391 -1 重度自閉症
177 D -1.684969807 -1 重度自閉症
178 D -1.660197304 -1 重度自閉症
179 D -1.649123393 -1 重度自閉症
180 D -1.63981362 -1 重度自閉症
181 D -1.634687753 -1 重度自閉症
182 D -1.632784327 -1 重度自閉症
183 D -1.632426472 -1 重度自閉症
表8.4d
      探針序列 探針位置
編號 群組 60 mer Chr
154 B ATGACAAATGTAAAGAATACAAAAGTAATCGATCTTACCTGGACTACTAGCATTCCAACT 6
155 B TGCTTCTTTTTCTTTCTGAGGCCAAATCTCGAGTCCATGTGTTTCTGATTCGTTTTTATT 2
156 B AATAAGAAAGAATTCTCTCTATCTGTCTTCGATAGCTCATTTCTTTTTATTGTTGCTTAA 20
157 B TAAACTTTTAAAGAAAGCAAGAATTGCATCGAAGTTTACGTTAGGCCTCTCTCTTAGGTT 6
158 B TCTTTCCTAATATAAGCATTAAAATCTATCGATGATTAAACCAGAAAGGAAAACAAAAGA 7
159 B CTCACCACCTCCTAGCTATGACCCTTGGTCGAGAGGCAAGAAATGCTTCAACCGTGCAAT 7
160 B GTCTTCTTTGTGTGGAGGAAGCAGTTTCTCGACCCCCTGCCCCTCACTGAGCCTTAGTTT 20
161 B CCCCACTCTGCCCTCAATTGTGGTTCATTCGAACTTTCTTCTAAAAAGCCTAAAATACTT 9
162 B TACATTGATTACAGAAAATCTTGTTATTTCGACAAAATAAATGTAGTAGAATTTCTTTGA 10
163 B GCTGCCTTCTTTCCATTGATGTTTCAATTCGAGACTCCTTCTCAAAAACAAAAACAACCA 6
164 B ACACTGCCTCCTCTCTTTGTCCCTCTAGTCGAACTATTTTGCAACTTTAGCTCCTATCCT 18
165 B ATCTATCCATTATCTATCTACCTATTTCTCGATTTAAAAAAAATAAAAATAAATAAATAA X
166 B ATTAGAATATTATCCTCACATTTCTAGGTCGATATACCATAGGTGTATAGTAGGTTATGC 6
167 B ATTACAATTTTTGATCACACTGTAATTTTCGAACTCAACAGGTCCTAAAAAGCTGCCTTC 9
168 D CTTAATCAATTGGAGTTTAACCTTTGGTTCGATTTTTCAATGTTTGTGACAAAACCGGTT 1
169 D ACACCCATTTTTAGGAATATTACAGTTGTCGATTGTATTTTGACAGGAAAGCAGAATGTA 3
170 D ACCATATGGTGACTTTATCTTTACTCCTTCGAGGGGAACTATTAAATATGAGTTAGGGTT 7
171 D TGTTTATCTCAAAAGAAGCTCAGAAAACTCGATTTTTAAGAGTCAAAGATTTTGATTTAA 6
172 D AATGAAACTGTAAGTTTCCCCAATTAAATCGAATCCGTAAATTCTAACACCTCCCTTCTT 21
173 D GTAAAAACAAAGCAAATTCTTCAAAATTTCGAATGAATAAAAAATTCATAAAAATAAGGC 4
174 D CAGAAAATTCAAATAAACTGTTAAAATTTCGATAGATCCTAATATTACTATTTAGTGGGC 9
175 D AATTCCATCTCAATTATAATTTTTTAACTCGATCTGCGATTGTTTGAATCTGCAGATGCA 4
176 D GCCCACTAAATAGTAATATTAGGATCTATCGAATTTGTGCTTGTTGGGAAAATAGTAATT 9
177 D TTGGAAAAGGTAAATTGTGTTTTGTAAATCGAACATCAGGTCAGAATTCCAAAGGGGCGT 6
178 D CGTAATGTTATTTTTAAAAACGTACTTTTCGAGGCATTCCAATAAAAATAAGTAAATTCT 18
179 D AGACTGGATCCGTCACTTTAGAACAGACTCGAGATTATCAGTAAGCTCTAGGGAAACTAG 2
180 D ATATTTTTTTTTTTTTGTATTCCCAGAATCGAAAAGAAGTTCTTTTTATCCCAAAGGAGT 18
181 D AAACTCAATGATAGAATTATTAAGGATTTCGACATTTTAAAAGGGCACTTGGAATTTCAC 16
182 D TCTTTTCTGTGGTTAAATTTTATAAGGATCGATTCAGCTGGGGAAAAATGAAAATAACAA 2
183 D TCTATATAAGAAATTCGTAGGATGAATATCGAATAATCTACCCATGGACATTTGTATCAC 2
表8.4e
      探針位置 4 kb 序列位置
編號 群組 起點 1 終點 1 起點 2 終點 2 Chr 起點 1
154 B 27448358 27448387 27502178 27502207 6 27448358
155 B 199605751 199605780 199669605 199669634 2 199605751
156 B 59641483 59641512 59702035 59702064 20 59641483
157 B 139979968 139979997 140011997 140012026 6 139979968
158 B 22299184 22299213 22370537 22370566 7 22295214
159 B 106136913 106136942 106205837 106205866 7 106136913
160 B 38255840 38255869 38273249 38273278 20 38255840
161 B 8143192 8143221 8167140 8167169 9 8139222
162 B 12569326 12569355 12596196 12596225 10 12565356
163 B 114033386 114033415 114113527 114113556 6 114033386
164 B 21178114 21178143 21194023 21194052 18 21178114
165 B 928034 928063 992081 992110 X 924064
166 B 146093834 146093863 146155394 146155423 6 146089864
167 B 92592449 92592478 92667360 92667389 9 92588479
168 D 229797491 229797520 229855687 229855716 1 229793521
169 D 182185817 182185846 182234334 182234363 3 182181847
170 D 29763052 29763081 29809503 29809532 7 29763052
171 D 137232225 137232254 137343854 137343883 6 137232225
172 D 30947499 30947528 30988071 30988100 21 30947499
173 D 23003950 23003979 23065931 23065960 4 22999980
174 D 28294415 28294444 28339600 28339629 9 28290445
175 D 105417618 105417647 105460123 105460152 4 105413648
176 D 28270700 28270729 28339600 28339629 9 28270700
177 D 46989663 46989692 47069677 47069706 6 46989663
178 D 58202024 58202053 58217905 58217934 18 58202024
179 D 195503344 195503373 195566638 195566667 2 195499374
180 D 11071110 11071139 11126627 11126656 18 11071110
181 D 68414194 68414223 68469116 68469145 16 68414194
182 D 39609951 39609980 39623227 39623256 2 39605981
183 D 227875569 227875598 227932093 227932122 2 227875569
表8.4f
      4 kb 序列位置   
編號 群組 終點 1 起點 2 終點 2 探針
154 B 27452357 27498208 27502207 ORF137_6_27448356_27449458_27496333_27502209_RF
155 B 199609750 199669605 199673604 ORF18_2_199605749_199608546_199669603_199675100_RR
156 B 59645482 59702035 59706034 ORF197_20_59641481_59643132_59702033_59707786_RR
157 B 139983967 140008027 140012026 ORF190_6_139979966_139988144_140005899_140012028_RF
158 B 22299213 22366567 22370566 ORF17_7_22293458_22299215_22368712_22370568_FF
159 B 106140912 106205837 106209836 ORF11_7_106136911_106139119_106205835_106208610_RR
160 B 38259839 38269279 38273278 ORF12_20_38255838_38257757_38271295_38273280_RF
161 B 8143221 8163170 8167169 ORF170_9_8138555_8143223_8162352_8167171_FF
162 B 12569355 12596196 12600195 ORF157_10_12567857_12569357_12596194_12598368_FR
163 B 114037385 114109557 114113556 ORF14_6_114033384_114036052_114107829_114113558_RF
164 B 21182113 21194023 21198022 ORF11_18_21178112_21180915_21194021_21196235_RR
165 B 928063 988111 992110 ORF169_X_922098_928065_989932_992112_FF
166 B 146093863 146155394 146159393 ORF147_6_146088385_146093865_146155392_146161780_FR
167 B 92592478 92667360 92671359 ORF179_9_92586435_92592480_92667358_92668932_FR
168 D 229797520 229851717 229855716 ORF148_1_229796281_229797522_229849427_229855718_FF
169 D 182185846 182234334 182238333 ORF121_3_182183246_182185848_182234332_182242013_FR
170 D 29767051 29809503 29813502 ORF166_7_29763050_29768509_29809501_29813015_RR
171 D 137236224 137339884 137343883 ORF18_6_137232223_137235679_137341897_137343885_RF
172 D 30951498 30984101 30988100 ORF147_21_30947497_30949256_30984126_30988102_RF
173 D 23003979 23065931 23069930 ORF197_4_22994756_23003981_23065929_23067873_FR
174 D 28294444 28335630 28339629 ORF115_9_28293258_28294446_28333777_28339631_FF
175 D 105417647 105456153 105460152 ORF17_4_105415477_105417649_105457783_105460154_FF
176 D 28274699 28335630 28339629 ORF125_9_28270698_28275294_28333777_28339631_RF
177 D 46993662 47065707 47069706 ORF162_6_46989661_46997140_47060758_47069708_RF
178 D 58206023 58213935 58217934 ORF103_18_58202022_58205094_58215328_58217936_RF
179 D 195503373 195562668 195566667 ORF167_2_195495210_195503375_195555062_195566669_FF
180 D 11075109 11122657 11126656 ORF118_18_11071108_11073538_11120542_11126658_RF
181 D 68418193 68465146 68469145 ORF1_16_68414192_68421728_68462182_68469147_RF
182 D 39609980 39623227 39627226 ORF16_2_39607186_39609982_39623225_39627003_FR
183 D 227879568 227928123 227932122 ORF144_2_227875567_227878014_227923203_227932124_RF
表8.4g
編號 群組 PCR- 引子 1_ID PCR_ 引子 1 PCR- 引子 2_ID PCR_ 引子 2
154 B OBD159_3965 GCTAAAAGAAGAAAACGATGAGGAGC OBD159_3967 GTCATTGGAGAGTGTCGGGCACAGAT
155 B OBD159_3969 TTTTGTCTTCCTGCCCCTCTTCCTGC OBD159_3971 GGTTCGGCAGAATCTTTGGACATCAA
156 B OBD159_3973 GGGACTGAATAGAGCAGGAAGACGGA OBD159_3975 GCACATCTGAATGACCTTCTAAGAGC
157 B OBD159_3977 GGACAGATTGTGAGGCACCCTTGGAT OBD159_3979 CTCCCGACTTTCTTCAGGTTTGTAAC
158 B OBD159_3981 CTTTCTGAGGTGGAAGCCCTGAT OBD159_3983 GCTTGAAAATCTCACTGTTGGTCCAC
159 B OBD159_3985 AAGAGCACGGACACCAAACAGGTCTA OBD159_3987 GGAGCAAAGAAAGGAAACTGAAGCCC
160 B OBD159_3989 GTGGAGGAGGTCAAGACTTCAGC OBD159_3991 GGAGATGGTGAGCCCAAGGCAGA
161 B OBD159_3993 CACCAGCAACACAGGAGAGGACC OBD159_3995 GCCTTGTCTTGCCCTTGAGTCTC
162 B OBD159_3997 CTGAGTCGGATGAACAGATGGTCTAC OBD159_3999 CTCTTCTGTTTGTGAGGGCTGCC
163 B OBD159_4001 ATCTTCCTCTCCTTCAATGGATGGCT OBD159_4003 GCCCAAAGATTACATCCATTCTGGTA
164 B OBD159_4005 ACAGTGGCTAAATCTCCTCCCTGGCT OBD159_4007 CAGAAGTTCCCTGTTGAGGTCTATCT
165 B OBD159_4009 CTTCTATCTTCCATCTACCTGTCTAT OBD159_4011 GTTCAGGAGGTCTGGTTACAGTTCCA
166 B OBD159_4013 AGGACTGCCAGGAACAAAGAGCCACT OBD159_4015 CTCTAAGTAAATCCTGGTCATTCCCC
167 B OBD159_4017 TCCATTCATTCTCCAGCCCAGGG OBD159_4019 GGACCGAGGAGGAGAGAGAGCAA
168 D OBD159_1009 CACAGCAACAAAAGCAACCTGGTGTC OBD159_1011 CCACCGATTTATTGCCCTGTAGGACA
169 D OBD159_845 GAGACTGAGGTTGCTTCCAATGTTCC OBD159_847 TCCTCAGATGATGTTTCGGCATTTGC
170 D OBD159_1145 GAAGAGACCTTATCCTTTTGAACTAC OBD159_1147 GAGTTTCAAGTGCCCTACTGGCTGA
171 D OBD159_1253 GGAAATGGTGGCGGGAAGGAGAAATG OBD159_1255 TCATCATCGTGGACAAGGAAAGCCTA
172 D OBD159_1005 GCATTCCAGGTCCAAGATGTCCT OBD159_1007 GTGGTGTGAGTTCAGGAGGGTTTAGG
173 D OBD159_1353 GGAACTACAGTGTCTTCTACAGGGAC OBD159_1355 TTCAACTGGTAAGACATTCTGAGGAA
174 D OBD159_817 GACATAGAATAATCTCCATCCATTGC OBD159_819 CTAAGTCCAGTAGTATGGTGGCTGTG
175 D OBD159_1181 TGAGAGGTTATGACTTTTCCGAGGTC OBD159_1183 GAAGACATACACAGTAAGCCCTCTGC
176 D OBD159_865 GCCTAAGTCCAGTAGTATGGTGGCTG OBD159_867 CAAGTCCTCATCTGTAGAGTCTGGAT
177 D OBD159_1137 GGTTGCTGGCTGGAGTCTTCTGA OBD159_1139 CCAACCAAATGGGAGGCAACGCC
178 D OBD159_761 TGTAGAGCCAAATAGCCACAGGGATA OBD159_763 TTGAGGCAGGAAGAAAGGTTTATGGC
179 D OBD159_1153 ACTCTGGCTCCGTTTCTTCCCTGACT OBD159_1155 AATACTGGCAAGAACCCATCTACTGC
180 D OBD159_825 CCTCACACAGTCCTCTTCCCACC OBD159_827 GCCTGTCACTCCAATCTGTGGTG
181 D OBD159_705 TGGAGAGGTGGAGGGAGGTAGGA OBD159_707 TGTCCTCCCTTCTCTTGCTCAGC
182 D OBD159_1101 GCTTAGATGTGGCTTTGTCTTTTCTC OBD159_1103 GACCTGGCTACTCTTGAAACACCCAC
183 D OBD159_993 CTTCTTCTCCTTGCCTTTCCTCTGGA OBD159_995 GGAGAAAAGACAAACCAGGGAAAGGG
表8.4h
編號 群組 探針 基因座 Probe_Count_Total
1 B ORF1_X_140889640_140892387_140922520_140927482_FF N/A N/A
2 A ORF13_12_10157054_10158072_10186674_10187896_FR N/A N/A
3 A ORF150_2_156262877_156267602_156333728_156335220_FR N/A N/A
4 A ORF191_3_168579832_168593354_168619477_168632678_RF N/A N/A
5 A ORF101_2_20454246_20457908_20490253_20493006_FR N/A N/A
6 A ORF107_7_38594689_38595956_38633652_38638705_RR N/A N/A
7 A ORF16_22_25661627_25666380_25694410_25695479_RF N/A N/A
8 B ORF18_1_230002404_230003670_230047264_230050830_RF N/A N/A
9 A ORF106_X_39224581_39226649_39303922_39309694_RF N/A N/A
10 A ORF143_6_146066540_146070987_146155392_146161780_FR N/A N/A
11 A ORF161_7_112014904_112016980_112124185_112133295_RR N/A N/A
12 A ORF141_1_77409324_77410804_77425166_77437348_FR N/A N/A
13 A ORF152_12_82605920_82610130_82624217_82631901_FR N/A N/A
14 A ORF163_3_177780034_177784103_177831413_177834825_FF N/A N/A
15 A ORF1_7_107580951_107585747_107694264_107700145_RF N/A N/A
16 B ORF194_9_106279286_106287735_106321634_106324034_RF N/A N/A
17 B ORF186_3_69167897_69172562_69214794_69217124_FF N/A N/A
18 B ORF196_16_68696944_68698250_68761044_68765212_RF N/A N/A
19 B ORF14_3_57937518_57938971_57949710_57950765_FF N/A N/A
20 B ORF102_10_112480267_112482497_112548771_112554911_FF N/A N/A
21 B ORF11_13_27255589_27257567_27309940_27312084_FR N/A N/A
22 B ORF16_21_32136037_32137869_32176222_32178848_RR N/A N/A
23 B ORF10_3_64194265_64195323_64266976_64268244_FF N/A N/A
24 B ORF17_16_68696944_68698250_68761044_68765212_RF N/A N/A
25 B ORF190_8_135269553_135271651_135319729_135326679_RR N/A N/A
26 B ORF18_12_12622611_12624189_12670151_12671586_RF N/A N/A
27 B ORF15_2_24032992_24034218_24049864_24051131_RR N/A N/A
28 B ORF179_16_21255119_21256642_21281450_21284082_FF N/A N/A
29 B ORF1_2_26896367_26898085_26908272_26910898_RF N/A N/A
30 B ORF17_16_11953475_11954578_12005204_12009260_FR N/A N/A
31 B ORF113_2_1847098_1851005_1898477_1903197_FF N/A N/A
32 B ORF149_11_101998219_102000306_102012864_102014476_RR N/A N/A
33 B ORF192_19_44155955_44161262_44257710_44261871_RR N/A N/A
34 B ORF14_3_10153541_10157825_10227245_10228950_RF N/A N/A
35 B ORF130_6_84763156_84765539_84812997_84816525_FR N/A N/A
36 B ORF107_20_24351934_24354072_24414516_24420566_FR N/A N/A
37 B ORF12_20_59933715_59935128_59974481_59977463_FR N/A N/A
38 B ORF148_9_85858972_85861060_85906428_85910620_FF N/A N/A
39 B ORF170_1_229849427_229855718_229885230_229889541_FF N/A N/A
40 B ORF118_5_26939582_26947847_26999889_27004744_RR N/A N/A
41 B ORF19_20_38250983_38253952_38329699_38336059_RR N/A N/A
42 B ORF10_1_81802434_81807125_81821654_81825564_FF N/A N/A
43 B ORF17_10_14331424_14334008_14346291_14350333_RR N/A N/A
44 B ORF14_1_155821962_155823515_155877897_155879214_FR N/A N/A
45 B ORF19_1_171350314_171354975_171418199_171422810_FF N/A N/A
46 B ORF165_3_69184131_69186136_69214794_69217124_FF N/A N/A
47 B ORF137_7_69585104_69587963_69620592_69625562_RR N/A N/A
48 B ORF173_16_21214034_21215549_21281450_21284082_FF N/A N/A
49 B ORF18_12_14122272_14125684_14156567_14160836_FF N/A N/A
50 B ORF160_2_102946170_102956566_102980783_102983000_FF N/A N/A
51 B ORF166_20_4539815_4545330_4603849_4605122_FR N/A N/A
表9.1a
編號 群組 Probe_Count_Sig HyperG_Stats FDR_HyperG Percent_Sig logFC AveExpr
1 B N/A N/A N/A N/A -0.766023397 -0.766023397
2 A N/A N/A N/A N/A -0.737400601 -0.737400601
3 A N/A N/A N/A N/A -0.736621417 -0.736621417
4 A N/A N/A N/A N/A -0.717890738 -0.717890738
5 A N/A N/A N/A N/A -0.715992935 -0.715992935
6 A N/A N/A N/A N/A -0.676084413 -0.676084413
7 A N/A N/A N/A N/A -0.666227638 -0.666227638
8 B N/A N/A N/A N/A -0.647142059 -0.647142059
9 A N/A N/A N/A N/A -0.63602694 -0.63602694
10 A N/A N/A N/A N/A -0.634695914 -0.634695914
11 A N/A N/A N/A N/A -0.632299188 -0.632299188
12 A N/A N/A N/A N/A -0.631116211 -0.631116211
13 A N/A N/A N/A N/A -0.628076664 -0.628076664
14 A N/A N/A N/A N/A -0.622972468 -0.622972468
15 A N/A N/A N/A N/A -0.621824228 -0.621824228
16 B N/A N/A N/A N/A -0.600571735 -0.600571735
17 B N/A N/A N/A N/A -0.599730862 -0.599730862
18 B N/A N/A N/A N/A -0.59643946 -0.59643946
19 B N/A N/A N/A N/A -0.593826424 -0.593826424
20 B N/A N/A N/A N/A -0.592608952 -0.592608952
21 B N/A N/A N/A N/A -0.5905716 -0.5905716
22 B N/A N/A N/A N/A -0.589865679 -0.589865679
23 B N/A N/A N/A N/A -0.584702175 -0.584702175
24 B N/A N/A N/A N/A -0.581952347 -0.581952347
25 B N/A N/A N/A N/A -0.576217342 -0.576217342
26 B N/A N/A N/A N/A -0.57612413 -0.57612413
27 B N/A N/A N/A N/A -0.573165149 -0.573165149
28 B N/A N/A N/A N/A -0.573108965 -0.573108965
29 B N/A N/A N/A N/A -0.571566802 -0.571566802
30 B N/A N/A N/A N/A -0.57074504 -0.57074504
31 B N/A N/A N/A N/A -0.570624243 -0.570624243
32 B N/A N/A N/A N/A -0.569711141 -0.569711141
33 B N/A N/A N/A N/A -0.56957071 -0.56957071
34 B N/A N/A N/A N/A -0.56643324 -0.56643324
35 B N/A N/A N/A N/A -0.564870426 -0.564870426
36 B N/A N/A N/A N/A -0.562624747 -0.562624747
37 B N/A N/A N/A N/A -0.557490402 -0.557490402
38 B N/A N/A N/A N/A -0.557072352 -0.557072352
39 B N/A N/A N/A N/A -0.554938528 -0.554938528
40 B N/A N/A N/A N/A -0.549675937 -0.549675937
41 B N/A N/A N/A N/A -0.547447117 -0.547447117
42 B N/A N/A N/A N/A -0.546608375 -0.546608375
43 B N/A N/A N/A N/A -0.545676557 -0.545676557
44 B N/A N/A N/A N/A -0.542994681 -0.542994681
45 B N/A N/A N/A N/A -0.541673976 -0.541673976
46 B N/A N/A N/A N/A -0.538217184 -0.538217184
47 B N/A N/A N/A N/A -0.53392007 -0.53392007
48 B N/A N/A N/A N/A -0.532182713 -0.532182713
49 B N/A N/A N/A N/A -0.531690361 -0.531690361
50 B N/A N/A N/A N/A -0.531489225 -0.531489225
51 B N/A N/A N/A N/A -0.53052259 -0.53052259
表9.1b
編號 群組 t P值 adj.P.Val B FC
1 B -2.306042889 0.039866719 0.10088678 -4.676737602 0.588036089
2 A -7.374301451 0.00000883 0.000292636 3.834979572 0.599819113
3 A -6.21630455 0.0000458 0.00086 2.14521907 0.600143156
4 A -7.239266686 0.0000106 0.000327941 3.647395871 0.607985685
5 A -4.638823995 0.000579337 0.004984216 -0.459547887 0.60878599
6 A -10.76833726 0.000000168 0.0000254 7.843989171 0.625861609
7 A -6.576257223 0.0000270 0.00060633 2.690445925 0.630152259
8 B -6.022669472 0.0000614 0.001050207 1.844287303 0.638544
9 A -4.915794296 0.000361906 0.003583857 0.022198152 0.643482608
10 A -8.950411064 0.00000122 0.0000840 5.854625604 0.644076557
11 A -7.655786319 0.00000607 0.0002294 4.218289153 0.64514744
12 A -5.163922573 0.000239554 0.002683371 0.445398777 0.645676663
13 A -5.179949705 0.000233322 0.002635975 0.472450904 0.647038443
14 A -5.179107163 0.000233645 0.002638339 0.471029649 0.649331693
15 A -11.80406641 0.0000000613 0.0000138 8.841413549 0.649848701
16 B -3.399761045 0.0053096 0.023575727 -2.705260335 0.659492549
17 B -4.976237297 0.000327043 0.003342724 0.12603745 0.659877045
18 B -5.236449377 0.000212681 0.002478314 0.567537287 0.661384225
19 B -5.077748476 0.000276195 0.002962952 0.299350813 0.662583222
20 B -5.897714777 0.0000744 0.001197159 1.647245776 0.663142603
21 B -7.852473041 0.00000470 0.000196323 4.480059218 0.664079745
22 B -8.231687828 0.00000290 0.000144892 4.971082696 0.664404763
23 B -7.853615673 0.00000469 0.000196129 4.481565602 0.666786974
24 B -5.936345249 0.0000701 0.001148541 1.708400927 0.668059105
25 B -6.658340911 0.0000239 0.000561201 2.812218346 0.670720061
26 B -7.818480733 0.00000491 0.000201589 4.435170262 0.670763397
27 B -6.927616081 0.0000163 0.000435268 3.205101362 0.672140551
28 B -2.486588452 0.028703988 0.080198262 -4.363759503 0.672166727
29 B -5.633193288 0.000112392 0.001580756 1.222758784 0.672885622
30 B -6.317387757 0.0000394 0.000777982 2.300188216 0.673269007
31 B -8.08428426 0.00000350 0.000162835 4.782324644 0.673325383
32 B -4.496046982 0.000741289 0.005894929 -0.711493194 0.673751675
33 B -5.741966192 0.0000947 0.00140648 1.398518872 0.67381726
34 B -4.049117715 0.001629916 0.010132186 -1.513989898 0.675284225
35 B -8.82030856 0.00000142 0.0000922 5.699089219 0.676016129
36 B -8.589705702 0.00000187 0.000110232 5.418692142 0.677069226
37 B -7.269873796 0.0000102 0.000319841 3.690126651 0.679483111
38 B -14.6932109 0.00000000526 0.00000401 11.20861049 0.679680034
39 B -7.340157635 0.00000925 0.000301595 3.787777594 0.680686061
40 B -14.89752535 0.00000000449 0.00000374 11.35629626 0.683173568
41 B -7.958150912 0.00000410 0.000179942 4.618685614 0.684229819
42 B -5.346720359 0.000177736 0.002185352 0.751855048 0.684627726
43 B -3.581214225 0.00380418 0.018301973 -2.370744948 0.685070061
44 B -7.767287642 0.00000525 0.000210217 4.367290619 0.686344746
45 B -12.25405337 0.0000000405 0.0000114 9.247930639 0.686973343
46 B -6.271807838 0.0000422 0.000814291 2.230490499 0.68862135
47 B -6.822148733 0.0000189 0.00048146 3.052417431 0.690675489
48 B -2.876798384 0.013979113 0.047496423 -3.665275055 0.691507732
49 B -4.093140425 0.001506656 0.00957795 -1.434120488 0.691743764
50 B -8.677436064 0.00000168 0.000102953 5.526084152 0.691840212
51 B -7.235636881 0.0000107 0.000329027 3.642319965 0.692303914
表9.1c
編號 群組 FC_1 LS 偵測到之環
1 B -1.700575899 -1 輕度自閉症
2 A -1.667169282 -1 輕度自閉症
3 A -1.666269105 -1 輕度自閉症
4 A -1.644775566 -1 輕度自閉症
5 A -1.642613358 -1 輕度自閉症
6 A -1.597797318 -1 輕度自閉症
7 A -1.586918061 -1 輕度自閉症
8 B -1.566062792 -1 輕度自閉症
9 A -1.554043556 -1 輕度自閉症
10 A -1.552610462 -1 輕度自閉症
11 A -1.550033277 -1 輕度自閉症
12 A -1.548762806 -1 輕度自閉症
13 A -1.545503224 -1 輕度自閉症
14 A -1.540044959 -1 輕度自閉症
15 A -1.538819725 -1 輕度自閉症
16 B -1.516317358 -1 輕度自閉症
17 B -1.515433833 -1 輕度自閉症
18 B -1.511980423 -1 輕度自閉症
19 B -1.509244374 -1 輕度自閉症
20 B -1.50797128 -1 輕度自閉症
21 B -1.505843248 -1 輕度自閉症
22 B -1.505106609 -1 輕度自閉症
23 B -1.499729358 -1 輕度自閉症
24 B -1.496873544 -1 輕度自閉症
25 B -1.490934979 -1 輕度自閉症
26 B -1.490838654 -1 輕度自閉症
27 B -1.487784063 -1 輕度自閉症
28 B -1.487726125 -1 輕度自閉症
29 B -1.486136675 -1 輕度自閉症
30 B -1.48529041 -1 輕度自閉症
31 B -1.485166051 -1 輕度自閉症
32 B -1.484226366 -1 輕度自閉症
33 B -1.4840819 -1 輕度自閉症
34 B -1.480857931 -1 輕度自閉症
35 B -1.479254646 -1 輕度自閉症
36 B -1.47695385 -1 輕度自閉症
37 B -1.471706925 -1 輕度自閉症
38 B -1.47128053 -1 輕度自閉症
39 B -1.469106034 -1 輕度自閉症
40 B -1.463756865 -1 輕度自閉症
41 B -1.461497252 -1 輕度自閉症
42 B -1.460647826 -1 輕度自閉症
43 B -1.459704718 -1 輕度自閉症
44 B -1.456993742 -1 輕度自閉症
45 B -1.455660557 -1 輕度自閉症
46 B -1.452176875 -1 輕度自閉症
47 B -1.447857954 -1 輕度自閉症
48 B -1.446115429 -1 輕度自閉症
49 B -1.445621994 -1 輕度自閉症
50 B -1.445420464 -1 輕度自閉症
51 B -1.444452328 -1 輕度自閉症
表9.1d
      探針序列 探針位置
編號 群組 60 mer Chr
1 B GTGTCTGTTCAAATTCTTTACCCATTTTTCGATGCTTTACTTTTGAGTTTGGGGGATGTC X
2 A ACAGATTAAAACTATGAGGATATACCATTCGAGTAATATTAAAGATTCCAGGACTCACAA 12
3 A GGGCTAACTTTATATTTTATAAATGTAGTCGATCTTCGTTTGAAACACAAGGTCTATCAC 2
4 A TTTGGATGTGTCATAATCTACTTAAAATTCGATACTTATCTTTACAAAACGCAAGAATAA 3
5 A CCAGCTTATTCTAAGTCCTCAATAAATCTCGAGAACAGCTACTTTCTATCTTCTGTTACA 2
6 A AAATATCAGGAGAATCCACATAGTAGTCTCGAACATCAGACTTGAATTTCTTGTTTTGGA 7
7 A ATTCTTTTAAACCTAAAATTAGACTGCTTCGACAAATTTATGATGCCTACATCATGAAGG 22
8 B TTTAAATATTTTAAATATTTTTAAAATATCGATTCTACTCCTCCAGGTTGCAGGCAGAGC 1
9 A GACCACAAAGTGAAGGTAAAAATAAAATTCGACTTTACAAATAATAATAATAGTCCAATG X
10 A CTGCTAATTTTAATTCACTAAGAAACTATCGATATACCATAGGTGTATAGTAGGTTATGC 6
11 A TCTTTTCTTCCTTTTCTCTTTCTTCCTTTCGACTATTTTATTTTTTGTAGAGACGAGATC 7
12 A ACATTTATTCCCTAATACTCTTCTCTGTTCGACAAAATTATCCTTCAAAAATGAAGGAGA 1
13 A AGGACAGAGTTTCAGAGTAAAATTTAATTCGAAAAACAAAAATAATAAATGCAATATTGA 12
14 A GATTCAGAATGTCTAGTATTTTATTCAATCGATTGATTTTTCCAAAATCACTGCTTCAAA 3
15 A TTTTCCAGTCCTATTTTCTATGGCAATGTCGAAAGTCTTTGAAAATAAACTCACCTAACG 7
16 B ATGAACAGGATATGTAATAATGGTATTATCGAGTCCCTTAAAAAATTTTAAAGGGGGAAA 9
17 B ATTGTGACAATCACATTTTAAGTACTCTTCGATATTCCCGTGTTCATTGTTAATTGTTTT 3
18 B TTGCTTTTTTATTTTTATTTTTTATTTTTCGACCTCACATGCCTCTTACATAGGCTTGAA 16
19 B ATCTTCTTTTTTTCAAAAGTATCCTAAGTCGAAGACGCACATTTTTTTCACATTTCAACA 3
20 B CCAGAGTAGTAAAATTGTGCTTTCTAATTCGAATACTTCCTGGACTCATCAAATTAAATG 10
21 B AGATCCCTTGTACACTGTATACTGTTTGTCGAATACATTTTTCTCTTTGAGTGGGAAGAA 13
22 B GTCTCAGTTCCACTGAGCATCTTGTACTTCGAGTATTATGTACTATACGTAATTGTATGT 21
23 B GCATTTTTATGAAATTAAATGTCCGTATTCGAGATTTTCACCAATAAGCTGAGTGGGAGG 3
24 B TTGCTTTTTTATTTTTATTTTTTATTTTTCGACCTCACATGCCTCTTACATAGGCTTGAA 16
25 B GTGTGTTAATAGAAGTAATATCACACTATCGATATACCTTTGCCACATGACCTATCAATA 8
26 B TGGGTATATTTTCTTTTTGTTTGGAAACTCGACTAGAAAAACTGGCAGAAAGGTTAGCAG 12
27 B ACACATTCCTTTCTTAAGAAATGTTAACTCGAGACCATCTCCCCCGGAGACGGTACCGGG 2
28 B TTTTTTTTTTTTAACATCTGTCTTCTCTTCGAGCTCCGCGCGCCGACCACGGGCAGCGGG 16
29 B GTAGTTTTTAATTTTGAAGTCCAATTTATCGACATCTGATTTCATTTCCCTTGGATATAT 2
30 B TAAAATTTTTTTTAAGAAGAAAAAAGACTCGACTGATTGATCAATTTAGTCCTTCTTGAG 16
31 B CCATCTTTAACAAGTGGTAAATTTTTTCTCGAGAAATATTCCAAGACCTCGTTTGAATAC 2
32 B CATGTATGAAATATGAAATTTGGAAGAATCGACTGCCACTATTTCACAGGTGATGACCTG 11
33 B CATGATACAAATTGTACTGCCATTTCCATCGACTTAGGTAAAAAACTTGACAAGAGACAA 19
34 B GATATTTGTAGTGGCATTTTTTTTTTTTTCGAATCTTGTGAATGTATTAAATATATCGCT 3
35 B TTTGTACAATTTGTTTTGTAGTTTCAACTCGATGATCAGCAAGAGCTTTTCTTCTTGCTG 6
36 B TTTTTATCTCTTCTAGATTTTGTCTTCCTCGATGTTGCTGATGCTACCAGGCTTAACAGG 20
37 B ATAATGTATAACACAAAATGTAAGAAGATCGAAGTTGAGTTGGAAATGCTTGGTGCATCA 20
38 B ATGAGAAACCTAAGGTCAGTTCTGGCTTTCGATACAAAGATTATAAATAAAATTGGCTGG 9
39 B AACCGGTTTTGTCACAAACATTGAAAAATCGATTATGAACTCAGAGACCAGGAAAATGAA 1
40 B TGCCGCATTTTTTGAATAAATTCACACATCGAAGAAAATGCTGAAGAATATCTTAATGAC 5
41 B CATCATCAGTTTATTTTTGGAGTTACATTCGAAACCCTGCTTTATTTTATTTATTTTTTT 20
42 B AGCTAAAAACTTTTCAAATTGATAGATTTCGAGACCATCTTGGCCAAGATGGTGAAATCC 1
43 B ATTAATTTCTTCCCCCTAGTTTCTTATTTCGAATTATTTAGATGATTGTCTCAATATTCC 10
44 B TGTTTTGTCCAGAAATAAGACACAGATGTCGACTTTAGCTCATTTTCCACCTTTCTCTGA 1
45 B TTCTCAAACTCTTCTTATGTTCAAACTGTCGATCTCTGGCTTTGGCTTCCCAAAGCACTG 1
46 B ATTACATTAAGTGAAATGTTAACTTCATTCGATATTCCCGTGTTCATTGTTAATTGTTTT 3
47 B AGTATGGAATATACTTTAGATAATAGTGTCGACTACAGAAAAAATATTCCCAGCACGTAA 7
48 B TTGCTTTAATAGGAAAATGAAAAACCTGTCGAGCTCCGCGCGCCGACCACGGGCAGCGGG 16
49 B TCAAATTTCAACATAAGATTTGAAAAAGTCGAATATATATTAAACATCTACACTGTGTCA 12
50 B TTCTCTTCTTTATTGCATTAATCTGGTTTCGATGGGCCCTCTTTCCAAAAATGCAGGTAT 2
51 B AACTTTGGGTTTAGTTTGTTCGTCTTTCTCGAACATTCTCCTGGCTGTTTACGTTTACAG 20
表9.1e
      探針位置 4 kb 序列位置
編號 群組 起點 1 終點 1 起點 2 終點 2 Chr 起點 1
1 B 140892356 140892385 140927451 140927480 X 140888386
2 A 10158041 10158070 10186676 10186705 12 10154071
3 A 156267571 156267600 156333730 156333759 2 156263601
4 A 168579834 168579863 168632647 168632676 3 168579834
5 A 20457877 20457906 20490255 20490284 2 20453907
6 A 38594691 38594720 38633654 38633683 7 38594691
7 A 25661629 25661658 25695448 25695477 22 25661629
8 B 230002406 230002435 230050799 230050828 1 230002406
9 A 39224583 39224612 39309663 39309692 X 39224583
10 A 146070956 146070985 146155394 146155423 6 146066986
11 A 112014906 112014935 112124187 112124216 7 112014906
12 A 77410773 77410802 77425168 77425197 1 77406803
13 A 82610099 82610128 82624219 82624248 12 82606129
14 A 177784072 177784101 177834794 177834823 3 177780102
15 A 107580953 107580982 107700114 107700143 7 107580953
16 B 106279288 106279317 106324003 106324032 9 106279288
17 B 69172531 69172560 69217093 69217122 3 69168561
18 B 68696946 68696975 68765181 68765210 16 68696946
19 B 57938940 57938969 57950734 57950763 3 57934970
20 B 112482466 112482495 112554880 112554909 10 112478496
21 B 27257536 27257565 27309942 27309971 13 27253566
22 B 32136039 32136068 32176224 32176253 21 32136039
23 B 64195292 64195321 64268213 64268242 3 64191322
24 B 68696946 68696975 68765181 68765210 16 68696946
25 B 135269555 135269584 135319731 135319760 8 135269555
26 B 12622613 12622642 12671555 12671584 12 12622613
27 B 24032994 24033023 24049866 24049895 2 24032994
28 B 21256611 21256640 21284051 21284080 16 21252641
29 B 26896369 26896398 26910867 26910896 2 26896369
30 B 11954547 11954576 12005206 12005235 16 11950577
31 B 1850974 1851003 1903166 1903195 2 1847004
32 B 101998221 101998250 102012866 102012895 11 101998221
33 B 44155957 44155986 44257712 44257741 19 44155957
34 B 10153543 10153572 10228919 10228948 3 10153543
35 B 84765508 84765537 84812999 84813028 6 84761538
36 B 24354041 24354070 24414518 24414547 20 24350071
37 B 59935097 59935126 59974483 59974512 20 59931127
38 B 85861029 85861058 85910589 85910618 9 85857059
39 B 229855687 229855716 229889510 229889539 1 229851717
40 B 26939584 26939613 26999891 26999920 5 26939584
41 B 38250985 38251014 38329701 38329730 20 38250985
42 B 81807094 81807123 81825533 81825562 1 81803124
43 B 14331426 14331455 14346293 14346322 10 14331426
44 B 155823484 155823513 155877899 155877928 1 155819514
45 B 171354944 171354973 171422779 171422808 1 171350974
46 B 69186105 69186134 69217093 69217122 3 69182135
47 B 69585106 69585135 69620594 69620623 7 69585106
48 B 21215518 21215547 21284051 21284080 16 21211548
49 B 14125653 14125682 14160805 14160834 12 14121683
50 B 102956535 102956564 102982969 102982998 2 102952565
51 B 4545299 4545328 4603851 4603880 20 4541329
表9.1f
   B 4 kb 序列位置   
編號 群組 終點 1 起點 2 終點 2 探針
1 B 140892385 140923481 140927480 ORF1_X_140889640_140892387_140922520_140927482_FF
2 A 10158070 10186676 10190675 ORF13_12_10157054_10158072_10186674_10187896_FR
3 A 156267600 156333730 156337729 ORF150_2_156262877_156267602_156333728_156335220_FR
4 A 168583833 168628677 168632676 ORF191_3_168579832_168593354_168619477_168632678_RF
5 A 20457906 20490255 20494254 ORF101_2_20454246_20457908_20490253_20493006_FR
6 A 38598690 38633654 38637653 ORF107_7_38594689_38595956_38633652_38638705_RR
7 A 25665628 25691478 25695477 ORF16_22_25661627_25666380_25694410_25695479_RF
8 B 230006405 230046829 230050828 ORF18_1_230002404_230003670_230047264_230050830_RF
9 A 39228582 39305693 39309692 ORF106_X_39224581_39226649_39303922_39309694_RF
10 A 146070985 146155394 146159393 ORF143_6_146066540_146070987_146155392_146161780_FR
11 A 112018905 112124187 112128186 ORF161_7_112014904_112016980_112124185_112133295_RR
12 A 77410802 77425168 77429167 ORF141_1_77409324_77410804_77425166_77437348_FR
13 A 82610128 82624219 82628218 ORF152_12_82605920_82610130_82624217_82631901_FR
14 A 177784101 177830824 177834823 ORF163_3_177780034_177784103_177831413_177834825_FF
15 A 107584952 107696144 107700143 ORF1_7_107580951_107585747_107694264_107700145_RF
16 B 106283287 106320033 106324032 ORF194_9_106279286_106287735_106321634_106324034_RF
17 B 69172560 69213123 69217122 ORF186_3_69167897_69172562_69214794_69217124_FF
18 B 68700945 68761211 68765210 ORF196_16_68696944_68698250_68761044_68765212_RF
19 B 57938969 57946764 57950763 ORF14_3_57937518_57938971_57949710_57950765_FF
20 B 112482495 112550910 112554909 ORF102_10_112480267_112482497_112548771_112554911_FF
21 B 27257565 27309942 27313941 ORF11_13_27255589_27257567_27309940_27312084_FR
22 B 32140038 32176224 32180223 ORF16_21_32136037_32137869_32176222_32178848_RR
23 B 64195321 64264243 64268242 ORF10_3_64194265_64195323_64266976_64268244_FF
24 B 68700945 68761211 68765210 ORF17_16_68696944_68698250_68761044_68765212_RF
25 B 135273554 135319731 135323730 ORF190_8_135269553_135271651_135319729_135326679_RR
26 B 12626612 12667585 12671584 ORF18_12_12622611_12624189_12670151_12671586_RF
27 B 24036993 24049866 24053865 ORF15_2_24032992_24034218_24049864_24051131_RR
28 B 21256640 21280081 21284080 ORF179_16_21255119_21256642_21281450_21284082_FF
29 B 26900368 26906897 26910896 ORF1_2_26896367_26898085_26908272_26910898_RF
30 B 11954576 12005206 12009205 ORF17_16_11953475_11954578_12005204_12009260_FR
31 B 1851003 1899196 1903195 ORF113_2_1847098_1851005_1898477_1903197_FF
32 B 102002220 102012866 102016865 ORF149_11_101998219_102000306_102012864_102014476_RR
33 B 44159956 44257712 44261711 ORF192_19_44155955_44161262_44257710_44261871_RR
34 B 10157542 10224949 10228948 ORF14_3_10153541_10157825_10227245_10228950_RF
35 B 84765537 84812999 84816998 ORF130_6_84763156_84765539_84812997_84816525_FR
36 B 24354070 24414518 24418517 ORF107_20_24351934_24354072_24414516_24420566_FR
37 B 59935126 59974483 59978482 ORF12_20_59933715_59935128_59974481_59977463_FR
38 B 85861058 85906619 85910618 ORF148_9_85858972_85861060_85906428_85910620_FF
39 B 229855716 229885540 229889539 ORF170_1_229849427_229855718_229885230_229889541_FF
40 B 26943583 26999891 27003890 ORF118_5_26939582_26947847_26999889_27004744_RR
41 B 38254984 38329701 38333700 ORF19_20_38250983_38253952_38329699_38336059_RR
42 B 81807123 81821563 81825562 ORF10_1_81802434_81807125_81821654_81825564_FF
43 B 14335425 14346293 14350292 ORF17_10_14331424_14334008_14346291_14350333_RR
44 B 155823513 155877899 155881898 ORF14_1_155821962_155823515_155877897_155879214_FR
45 B 171354973 171418809 171422808 ORF19_1_171350314_171354975_171418199_171422810_FF
46 B 69186134 69213123 69217122 ORF165_3_69184131_69186136_69214794_69217124_FF
47 B 69589105 69620594 69624593 ORF137_7_69585104_69587963_69620592_69625562_RR
48 B 21215547 21280081 21284080 ORF173_16_21214034_21215549_21281450_21284082_FF
49 B 14125682 14156835 14160834 ORF18_12_14122272_14125684_14156567_14160836_FF
50 B 102956564 102978999 102982998 ORF160_2_102946170_102956566_102980783_102983000_FF
51 B 4545328 4603851 4607850 ORF166_20_4539815_4545330_4603849_4605122_FR
表9.1g
編號 群組 PCR- 引子 1_ID PCR_ 引子 1 PCR- 引子 2_ID PCR_ 引子 2
1 B OBD159_4021 GGTAGTAGGAATGAAAGAGTAGAAAG OBD159_4023 GGAGGTGAGGGCATAATAGAAACCAT
2 A OBD159_885 CCTGAGCAACAAGAGCGAAACTC OBD159_887 CATCAGGCTTCTGGGAATGGAAAT
3 A OBD159_1057 GAAGTCCATTCTTGGGATGAAACAAA OBD159_1059 GGCTCTAAGATTGAGGCTGTGAT
4 A OBD159_1313 GACATTGGCAGAGGTAAATAAATA OBD159_1315 CAGTCCAAAAGCCAAGAAAGCATA
5 A OBD159_745 GCCCTCTACTGCCTCAGGTTCTT OBD159_747 TCCGACCAACCCAGACCAACCTG
6 A OBD159_769 ATGTCTTTATCTTGCTTCCTTTAGGG OBD159_771 AGAGCCAGTCCGAGTTCCAAAAC
7 A OBD159_1113 TGTGCTAATCTGGAAGACTCTGTC OBD159_1115 AAGTAACAGAGTAAGAAGAAATAC
8 B OBD159_4025 TACTGTACTCCAGCCTGGGTAATAGAGCC OBD159_4027 ACAAGGGTGGGGTTGGTGGACATTTC
9 A OBD159_765 TGAAAGAAAGAGGTTGTCAAGAAT OBD159_767 TTTTCTGCCTCAGCCTCCCAAGTA
10 A OBD159_985 GGCTAAACCCACACCCTGTAATAACC OBD159_987 CTCTAAGTAAATCCTGGTCATTCCCC
11 A OBD159_1133 TGCCACCCAGTAGGTCTCAGTCT OBD159_1135 GAGACCAGGAACTCAGGACCAGC
12 A OBD159_977 AAGTCAGAAAGCCACAAGATAAAT OBD159_979 AAAGTGCTGGGATTACAGGCGTGA
13 A OBD159_1073 CGTGACGAACTGAAGCAGACCCTTTC OBD159_1075 CATCCTTTATCTTCCCTACCCCATCA
14 A OBD159_1141 ATGTGAGTGTTCCTTGTAGATTAC OBD159_1143 AGGTCTCAAGCAAGGGAGCAACAT
15 A OBD159_709 CAACTGTGACTTGACTCCTTGCTAAG OBD159_711 CTGAGACAAGGCAGGGCAGGTGTTA
16 B OBD159_4029 CACAGCAAGACTCAGGGTGGAACAGCCC OBD159_4031 GCCCAAACTCACAAAGCCTACAGAGGGA
17 B OBD159_4033 TAACTGGTTTTGTATCTAATTTAGTAGTCT OBD159_4035 TTTACTGGATTAATTCTTAGTTGAA
18 B OBD159_4037 TTTGGAAAGAGGCATCACTTTTAT OBD159_4039 CAAGAGATTGAGACTATCCTGGCCAAC
19 B OBD159_4041 TGGGATTTCAGGCCTGAGCCACC OBD159_4043 TTGCCCAGGCTGGAGTGTAGTGGC
20 B OBD159_4045 GGGCTTTCTCCCTACTCTGTTTAGA OBD159_4047 CTCCCACTCTCTACCTCTCCCTAAGT
21 B OBD159_4049 GCTGGCAGGTTCGGTGTCTTGTG OBD159_4051 GACCCGTCCCCTGATAACTGATG
22 B OBD159_4053 CTTCTCAGGTGCTGCCCTCCTCCG OBD159_4055 GCTCAATGAACTATGTGCTGCTGTAAGC
23 B OBD159_4057 ACCCCTTATTTGGAGTGAGCAGAGGCAA OBD159_4059 GGGCTCCGCACAAGGCAGGTAACATTCC
24 B OBD159_4061 CCAATATTAAAATGCATCACCAAACC OBD159_4063 GGCAGGAGAATCGCTTGAACCCAGGA
25 B OBD159_4065 GAGATGGCTTGATTGTCTTGCCCAAC OBD159_4067 GCTTCCCATTAGCACAACACTGCCAA
26 B OBD159_4069 ACCTGAAACTCCTGGTGCCACAAGC OBD159_4071 AAGTCTACTCACATCTTCCTGCTGCT
27 B OBD159_4073 GTGTCTCTCAGGCTGCTGTCCATCATCC OBD159_4075 ACCCTCCACGCCACCTCCGAATCAGACC
28 B OBD159_4077 ATCCGCCTGCCTTGGCCTCCCAAAGTG OBD159_4079 GGTTGGGGCTCCTCATCCCAACA
29 B OBD159_4081 GCCCGCCCCAGCCTCCCAAAGTGC OBD159_4083 GATAATCTCATTGTGGTTTTAACTTGT
30 B OBD159_4085 GGAGGCTGAGGCAGAAGATAGA OBD159_4087 TTGATTAATGATCCTGTGTCTAAGT
31 B OBD159_4089 CCCACCCCGCTTGAATAGTCTGG OBD159_4091 GAGTGACCACCACCGCTCAACTA
32 B OBD159_4093 ATCTGTCTACCTCGGCCTGCAAAG OBD159_4095 TGCTTACAAAGAGATCCTTATCACCCTG
33 B OBD159_4097 ATGTCGTCCTGCTTCTGGAACAGTCTC OBD159_4099 TATGTATTCTGCTGGTTTTAGGTGGG
34 B OBD159_4101 CCTCCTCCAGGCTTGGGAAAGTG OBD159_4103 CACCACACAACACACCCTGCCTA
35 B OBD159_4105 GCACGCCCTTTCCGCAGCCCACCTTTTC OBD159_4107 CTCAGTCACCTGGCTACACCCAAGTGC
36 B OBD159_4109 CTATTTGCTGAAGGTTGAGTAGTCTT OBD159_4111 TAAGGGCTCACCAGCATTGGATTTGG
37 B OBD159_4113 CTCAGTTGTGGACCAGAGCAGAT OBD159_4115 CACCCCACACTGTCACTCTTTGCTCT
38 B OBD159_4117 CTGTCAGCATTGTGGGCAAGACCCTGGG OBD159_4119 GGAAAGGTAGGGCACGCCTGTCATCCC
39 B OBD159_4121 GCTTTGCTTCACAGGCTTGCCCA OBD159_4123 CTGACACGATGGGACCAGTGCCA
40 B OBD159_4125 CAATTCTCTATGGTATATTATTGTTCTT OBD159_4127 AAATATTTGTAACACATATCTGATAAG
41 B OBD159_4129 TTAAAGTAGTTTATTTTCACAGAAA OBD159_4131 GTCTTGAACTCCTGACTTCAAGTG
42 B OBD159_4133 ATCTGATTTTGAGTCTTGAAGGGAG OBD159_4135 GCTCAGCTAAGAGTGCAATGGC
43 B OBD159_4137 AAGTGCTGGGAATGCAGGTGTGA OBD159_4139 CCTTGTAACACATACAACCACTGGATTT
44 B OBD159_4141 TAACAAAATGAAAGAGAAAAAAACA OBD159_4143 GGCGGATTGCTTGACCCCAGGAA
45 B OBD159_4145 GCAACTGGGTAGTCTTCCTCGGG OBD159_4147 CACACCCACGAGTCAGAGGTAAC
46 B OBD159_4149 GCTACTTGGAAGGCTGAGGGGGGAGAA OBD159_4151 TACTGGATTAATTCTTAGTTGAA
47 B OBD159_4153 GGCAGAAGACACAGTGGGACCAGGG OBD159_4155 CATTTTCCACCCACCTTCCCACACCCG
48 B OBD159_4157 GCCTCATTTGGGCAGATGTCTTCCTTTC OBD159_4159 GCGGCGGCGAGGCTTGAGCAGTG
49 B OBD159_4161 CCATTAGGCTCCCACATCCAACATTG OBD159_4163 GCCCACCCCATAGTAAAAGACTTGAC
50 B OBD159_4165 CTATTTGCTTCCATCTCTTCTTCAAG OBD159_4167 GCCTTGAGCCAATGTTGAACCCAGTA
51 B OBD159_4169 GGTGTCAACTGTAGTGTTTCCATTTTCA OBD159_4171 CACGATGAGTATGAAGGGCAGAGCGTTT
表9.1h
編號 群組 探針 基因座 Probe_Count_Total
52 B ORF14_1_31540047_31543886_31587537_31592007_FF N/A N/A
53 B ORF119_2_218948268_218952031_218967854_218969392_RR N/A N/A
54 B ORF18_2_47506510_47507935_47522457_47530546_RR N/A N/A
55 B ORF18_8_22370928_22373682_22477274_22479031_FF N/A N/A
56 B ORF19_21_17395228_17399850_17441050_17442330_RR N/A N/A
57 B ORF163_9_127769656_127771134_127789432_127791005_RR N/A N/A
58 B ORF116_2_242067121_242068527_242133611_242136266_FF N/A N/A
59 B ORF17_1_81722088_81728566_81795686_81801062_FR N/A N/A
60 B ORF1_2_227767541_227769435_227779837_227782633_RF N/A N/A
61 B ORF12_6_489302_494492_562962_566609_FR N/A N/A
62 B ORF106_7_16777840_16784530_16819587_16825123_FR N/A N/A
63 B ORF19_20_38329699_38336059_38443612_38450633_RR N/A N/A
64 B ORF15_16_14002832_14006140_14029360_14030604_RR N/A N/A
65 B ORF13_4_125301039_125303568_125344175_125348116_FF N/A N/A
66 B ORF14_6_134270140_134271366_134318303_134322289_FF N/A N/A
67 B ORF158_14_73160989_73163045_73174453_73177740_RF N/A N/A
68 B ORF156_13_60855031_60860383_60904843_60913572_FR N/A N/A
69 B ORF1_2_28511589_28516309_28600362_28606396_RR N/A N/A
70 B ORF19_6_134285274_134289662_134322425_134324942_FR N/A N/A
71 B ORF145_16_14002832_14006140_14029360_14030604_RR N/A N/A
72 B ORF12_15_59226397_59229578_59275124_59282145_FF N/A N/A
73 B ORF127_4_87521130_87535092_87627331_87629853_FF N/A N/A
74 B ORF10_8_29194737_29197133_29221895_29223912_RR N/A N/A
75 B ORF102_1_91729836_91735039_91769176_91774685_FF N/A N/A
76 B ORF12_8_9827711_9830539_9907504_9913050_RF N/A N/A
77 B ORF182_5_7525226_7526562_7606244_7610178_FR N/A N/A
78 B ORF11_19_10462371_10464602_10512340_10514192_FF N/A N/A
79 B ORF107_5_7540900_7542383_7560907_7566450_FF N/A N/A
80 B ORF19_5_53082652_53086261_53104495_53107169_RR N/A N/A
81 B ORF146_7_158585412_158588279_158654906_158659127_FR N/A N/A
82 B ORF10_18_23950674_23952569_24015103_24017541_RR N/A N/A
83 B ORF160_6_111460815_111466030_111524702_111525757_RR N/A N/A
84 B ORF14_2_24009691_24012849_24049864_24051131_FR N/A N/A
85 B ORF153_7_16086203_16100539_16133512_16139722_FF N/A N/A
86 B ORF140_20_57363873_57366958_57379133_57382850_RR N/A N/A
87 B ORF159_2_16713427_16718029_16757015_16758385_RR N/A N/A
88 C ORF19_21_41926859_41930173_41979620_41986582_RR N/A N/A
89 C ORF171_4_152168385_152172738_152243834_152246201_FR N/A N/A
90 C ORF14_7_22502113_22509109_22587350_22592472_RR N/A N/A
91 C ORF13_12_83913616_83915585_83954032_83957600_FR N/A N/A
92 C ORF104_12_82663103_82673256_82704442_82708010_RR N/A N/A
93 C ORF139_14_68325745_68327713_68392804_68395555_FF N/A N/A
94 C ORF15_2_41904272_41908286_41953265_41954493_RF N/A N/A
95 C ORF107_10_50601158_50604736_50643028_50654450_FF N/A N/A
96 C ORF131_9_111939947_111941193_112015341_112018045_FF N/A N/A
97 C ORF168_3_43042539_43050797_43066697_43075829_RF N/A N/A
98 C ORF13_1_83403878_83408459_83447955_83452928_FF N/A N/A
99 C ORF19_20_19870175_19876327_19917735_19921318_FR N/A N/A
100 C ORF105_1_197427797_197435397_197468569_197471959_RF N/A N/A
101 C ORF17_3_120801777_120809148_120844722_120858831_FR N/A N/A
102 C ORF16_11_47464161_47467927_47526127_47528647_FF N/A N/A
表9.2a
編號 群組 Probe_Count_Sig HyperG_Stats FDR_HyperG Percent_Sig logFC AveExpr
52 B N/A N/A N/A N/A -0.529395969 -0.529395969
53 B N/A N/A N/A N/A -0.527638119 -0.527638119
54 B N/A N/A N/A N/A -0.527523869 -0.527523869
55 B N/A N/A N/A N/A -0.527016307 -0.527016307
56 B N/A N/A N/A N/A -0.526648103 -0.526648103
57 B N/A N/A N/A N/A -0.526047264 -0.526047264
58 B N/A N/A N/A N/A -0.525971711 -0.525971711
59 B N/A N/A N/A N/A -0.522903803 -0.522903803
60 B N/A N/A N/A N/A -0.521712317 -0.521712317
61 B N/A N/A N/A N/A -0.520936683 -0.520936683
62 B N/A N/A N/A N/A -0.520151763 -0.520151763
63 B N/A N/A N/A N/A -0.519882289 -0.519882289
64 B N/A N/A N/A N/A -0.517203512 -0.517203512
65 B N/A N/A N/A N/A -0.516650168 -0.516650168
66 B N/A N/A N/A N/A -0.516240578 -0.516240578
67 B N/A N/A N/A N/A -0.514825173 -0.514825173
68 B N/A N/A N/A N/A -0.513073175 -0.513073175
69 B N/A N/A N/A N/A -0.512357312 -0.512357312
70 B N/A N/A N/A N/A -0.512210871 -0.512210871
71 B N/A N/A N/A N/A -0.511854022 -0.511854022
72 B N/A N/A N/A N/A -0.511674292 -0.511674292
73 B N/A N/A N/A N/A -0.510887414 -0.510887414
74 B N/A N/A N/A N/A -0.510879346 -0.510879346
75 B N/A N/A N/A N/A -0.510258222 -0.510258222
76 B N/A N/A N/A N/A -0.509727293 -0.509727293
77 B N/A N/A N/A N/A -0.509268221 -0.509268221
78 B N/A N/A N/A N/A -0.508188926 -0.508188926
79 B N/A N/A N/A N/A -0.507304055 -0.507304055
80 B N/A N/A N/A N/A -0.506922901 -0.506922901
81 B N/A N/A N/A N/A -0.50608615 -0.50608615
82 B N/A N/A N/A N/A -0.504510261 -0.504510261
83 B N/A N/A N/A N/A -0.503933309 -0.503933309
84 B N/A N/A N/A N/A -0.502710965 -0.502710965
85 B N/A N/A N/A N/A -0.502016712 -0.502016712
86 B N/A N/A N/A N/A -0.50169487 -0.50169487
87 B N/A N/A N/A N/A -0.501620823 -0.501620823
88 C N/A N/A N/A N/A -0.652403404 -0.652403404
89 C N/A N/A N/A N/A -0.647165032 -0.647165032
90 C N/A N/A N/A N/A -0.615550698 -0.615550698
91 C N/A N/A N/A N/A -0.61449779 -0.61449779
92 C N/A N/A N/A N/A -0.607775641 -0.607775641
93 C N/A N/A N/A N/A -0.607726195 -0.607726195
94 C N/A N/A N/A N/A -0.607072304 -0.607072304
95 C N/A N/A N/A N/A -0.604120415 -0.604120415
96 C N/A N/A N/A N/A -0.603262101 -0.603262101
97 C N/A N/A N/A N/A -0.600843342 -0.600843342
98 C N/A N/A N/A N/A -0.600791862 -0.600791862
99 C N/A N/A N/A N/A -0.59994654 -0.59994654
100 C N/A N/A N/A N/A -0.592026529 -0.592026529
101 C N/A N/A N/A N/A -0.588268908 -0.588268908
102 C N/A N/A N/A N/A -0.582205534 -0.582205534
表9.2b
編號 群組 t P值 adj.P.Val B FC
52 B -5.690762577 0.000102646 0.001487975 1.31599159 0.692844755
53 B -4.919995757 0.000359361 0.003565786 0.02943148 0.693689466
54 B -2.675926334 0.020268164 0.061543564 -4.027898971 0.693744402
55 B -5.741330707 0.0000948 0.001407517 1.397496922 0.693988515
56 B -8.750621085 0.00000154 0.0000975 5.614994568 0.694165657
57 B -3.527659902 0.00419664 0.019730707 -2.469421969 0.694454817
58 B -7.139301113 0.0000122 0.000358474 3.506957853 0.694491186
59 B -6.821672871 0.0000190 0.000481644 3.051725051 0.695969601
60 B -7.937569142 0.00000421 0.000183123 4.591796433 0.696544622
61 B -6.623946979 0.0000252 0.000578297 2.761309403 0.696919205
62 B -4.687821255 0.00053267 0.004706914 -0.373637152 0.697298478
63 B -5.652033695 0.000109099 0.001549567 1.253322473 0.697428735
64 B -4.522607316 0.000707922 0.005751261 -0.66444806 0.698724914
65 B -8.279333914 0.00000274 0.000139883 5.031532143 0.698992961
66 B -5.926417544 0.0000712 0.00115992 1.692704956 0.699191437
67 B -9.005921005 0.00000114 0.0000806 5.920413033 0.69987774
68 B -4.675777781 0.000543764 0.004769579 -0.39472724 0.700728182
69 B -6.048194344 0.0000591 0.001022569 1.884262734 0.701075968
70 B -6.810569759 0.0000193 0.000486577 3.035561098 0.701147135
71 B -4.352866432 0.00095165 0.006944731 -0.966430198 0.701320584
72 B -6.503963115 0.0000299 0.000650266 2.582412353 0.70140796
73 B -7.92396296 0.00000429 0.000185092 4.573991509 0.701790628
74 B -6.3701302 0.0000364 0.000738798 2.380469678 0.701794552
75 B -4.223801971 0.001194552 0.008083156 -1.19804568 0.702096761
76 B -7.615247067 0.00000641 0.000236522 4.163720233 0.702355189
77 B -4.077668423 0.001548838 0.009761952 -1.462172899 0.702578717
78 B -2.088762163 0.058824865 0.132391854 -5.041102442 0.70310452
79 B -8.065061478 0.00000358 0.000165297 4.757512949 0.703535898
80 B -6.691374518 0.0000228 0.000543343 2.860957982 0.703721794
81 B -3.113255034 0.009018206 0.034017867 -3.23295053 0.704130065
82 B -2.820885018 0.015504316 0.050521458 -3.766739026 0.704899623
83 B -7.596010808 0.00000657 0.000240006 4.137752552 0.705181578
84 B -7.743606851 0.00000541 0.000214421 4.33577836 0.705779306
85 B -4.645302371 0.000572929 0.0049448 -0.448172394 0.706119023
86 B -3.251265086 0.006984607 0.028816277 -2.979033184 0.706276564
87 B -3.17771015 0.008003188 0.03102913 -3.114458829 0.706312815
88 C -4.116449219 0.001445338 0.009299015 -1.391897027 0.636219544
89 C -5.250916799 0.00020771 0.002439261 0.591815066 0.638533832
90 C -8.077603511 0.00000353 0.000163777 4.77370666 0.652680708
91 C -7.031456546 0.0000141 0.000395406 3.353937492 0.653157222
92 C -6.824378577 0.0000189 0.000480364 3.055661441 0.656207669
93 C -4.680678233 0.000539221 0.004740769 -0.386143641 0.65623016
94 C -4.417314421 0.000850172 0.006506693 -0.851406678 0.656527658
95 C -3.68903726 0.003123853 0.015776466 -2.17232846 0.657872351
96 C -3.095886903 0.00931321 0.034876334 -3.264843305 0.65826386
97 C -5.867551598 0.0000779 0.001234191 1.599346596 0.659368402
98 C -5.934080716 0.0000703 0.001151203 1.70482188 0.659391931
99 C -6.624898406 0.0000251 0.000578066 2.762719907 0.659778403
100 C -8.923879856 0.00000126 0.0000857 5.823061426 0.663410371
101 C -3.189650431 0.007828185 0.030504397 -3.092488015 0.665140532
102 C -8.509149731 0.00000206 0.000117329 5.319296317 0.667941874
表9.2c
編號 群組 FC_1 LS 偵測到之環
52 B -1.443324775 -1 輕度自閉症
53 B -1.441567228 -1 輕度自閉症
54 B -1.441453072 -1 輕度自閉症
55 B -1.440946036 -1 輕度自閉症
56 B -1.440578326 -1 輕度自閉症
57 B -1.439978492 -1 輕度自閉症
58 B -1.439903084 -1 輕度自閉症
59 B -1.436844367 -1 輕度自閉症
60 B -1.435658203 -1 輕度自閉症
61 B -1.434886559 -1 輕度自閉症
62 B -1.4341061 -1 輕度自閉症
63 B -1.433838255 -1 輕度自閉症
64 B -1.431178393 -1 輕度自閉症
65 B -1.430629572 -1 輕度自閉症
66 B -1.430223465 -1 輕度自閉症
67 B -1.428820983 -1 輕度自閉症
68 B -1.427086887 -1 輕度自閉症
69 B -1.426378945 -1 輕度自閉症
70 B -1.426234167 -1 輕度自閉症
71 B -1.425881434 -1 輕度自閉症
72 B -1.425703809 -1 輕度自閉症
73 B -1.42492641 -1 輕度自閉症
74 B -1.424918442 -1 輕度自閉症
75 B -1.424305103 -1 輕度自閉症
76 B -1.423781038 -1 輕度自閉症
77 B -1.423328057 -1 輕度自閉症
78 B -1.422263649 -1 輕度自閉症
79 B -1.421391577 -1 輕度自閉症
80 B -1.4210161 -1 輕度自閉症
81 B -1.420192163 -1 輕度自閉症
82 B -1.418641701 -1 輕度自閉症
83 B -1.418074481 -1 輕度自閉症
84 B -1.416873507 -1 輕度自閉症
85 B -1.416191843 -1 輕度自閉症
86 B -1.415875949 -1 輕度自閉症
87 B -1.41580328 -1 輕度自閉症
88 B -1.571784471 -1 輕度自閉症
89 B -1.56608773 -1 輕度自閉症
90 B -1.532142727 -1 輕度自閉症
91 B -1.531024946 -1 輕度自閉症
92 B -1.523907823 -1 輕度自閉症
93 B -1.523855594 -1 輕度自閉症
94 B -1.523165075 -1 輕度自閉症
95 B -1.520051723 -1 輕度自閉症
96 B -1.519147656 -1 輕度自閉症
97 B -1.516602853 -1 輕度自閉症
98 B -1.516548737 -1 輕度自閉症
99 B -1.515660402 -1 輕度自閉症
100 B -1.507362628 -1 輕度自閉症
101 B -1.503441682 -1 輕度自閉症
102 B -1.497136261 -1 輕度自閉症
表9.2d
      探針序列 探針位置
編號 群組 60 mer Chr
52 B TTTTTGTATTTTTAATAGAGAAATGGCCTCGAAGGAGCTAAAGTGAGTGAAGCACATAGT 1
53 B TTTTCTTTCTTTCATTTTTTTTTTTTTTTCGACTTAATAGACTCCTCCTTCTCATCATCA 2
54 B AGCAAAAAGTGAAGACTGCTTGACTTTTTCGAAAAGGCCTTTGGTCAAACGATCATATTT 2
55 B TATAAGACAGTAATTTCAGAATTACTGTTCGATAGATCTCATACTTTGGTTTTAACACTG 8
56 B TAGTGTTTGATAACACAGGGAAAGTCTTTCGAAGTATTACTATTCTCACTTTATAGATGA 21
57 B TTTTCTTTATTTCTTTTTTTTTTTTTTTTCGAGTACTTGGCACCACCGCGCCGGAAGGGC 9
58 B GATGTCTGTAATTTATTCAAAGATTCTCTCGAAGAAAAAAGCAATAAGAAGCCTCAGCAA 2
59 B TAACTCATAGTCTAATACATAAGCACAATCGAGAGGCACTAAAAATTCAATTTGGACTAT 1
60 B GCATTGTTTCTTCATTTTATTTTATTTTTCGATCAGTCATAATCAGTCAATCATGGCAGT 2
61 B AATGTACATACTACACAACAGACAAATCTCGATGAAAGTAGGCAAAGAATATAATTTTGG 6
62 B AATTAAAAGAAAGTAATGGAAGAATTGATCGACTTTTATAAACGGGGGCACGTGTTCAGG 7
63 B AAAAAAATAAATAAAATAAAGCAGGGTTTCGAATAAAATAAAATTAGGGCCAGGCATGAT 20
64 B TCTTAATTTGATTTTCTCTGGCTCAGAATCGAGATATTACACTCCAGCCTGGGTGACGGA 16
65 B TCTTTACTAAAGAGAATCTATCTTGTATTCGAGGTTCAGAAATATTGTGCAACTTTTACA 4
66 B CATTCTTTTCGTTTGAATTTGTCTTTCCTCGAAAAAAATTACATTCCATTCAACAACTAA 6
67 B TCCATGGTTTCTCATAAAAATCAGTCATTCGATACAAGGTTTTACTGTGTCACCCAGGCT 14
68 B AACTCATACATTATCTATTTACTGAAAATCGATAGATGCAGAAAAGGTCTTCAATAAAAT 13
69 B ATTTTGAAAGCAGCAGGAGTAAAACTCTTCGATATGAACATTTTTACGGTTATTATGTTT 2
70 B GGTATGTATTTTACATCTAAAGTACATCTCGATCATATGCTTAAAACTCCAGCCACAGTG 6
71 B TCTTAATTTGATTTTCTCTGGCTCAGAATCGAGATATTACACTCCAGCCTGGGTGACGGA 16
72 B TGATAATGAAATGAAAAGAAGTTTCACCTCGAACAGAAGTTATTTAAATTCCCTATGGCT 15
73 B CTAAATTCCAAATCTCATTTAAATACCATCGATCTGTTTTAACTTTTTAAAATTTTGCAA 4
74 B TGATTTTTCCTTTATGCTTCTATGTTATTCGATACTTTATAAAATGAAAAACCTCTTCTT 8
75 B ATCATAATTAGAGAAAGTACTTCTCAAATCGATTGTGATGACCGAGACTTGTTCTCAGAC 1
76 B TTCTCTGTTTAATATATATATTTTTTCTTCGAATCGCAATAACAGCAAACAATACAGGTT 8
77 B TTTAATCATTACACCTTGTAAACAAGTATCGATAAAAATGTACTTCAAAAATTGGATTGG 5
78 B CACCTAGCTAATTTTTTAAAATTTTTTGTCGACGTGGCGTGCCCGGCGCGCACCTGTCCT 19
79 B TATTACAGAAAAAAAAAAATGGATCTCTTCGATCGTATCTCACTGGAGCTTCAAACTCCT 5
80 B TTGATAATGATATAGTAATGTAGTTTCATCGAAATTCCAAAAAACTGCATTTTTAGAACC 5
81 B GGCCTCTACCCGCGGGGCCCCGCGCGCGTCGAACACCTCTTATATGTAATGTATAAAATT 7
82 B AAAATGGCATATTATATCAATCTTTCACTCGACCTGCGGCCCCCGGGAGCCCCCTCCCCC 18
83 B GGACCACCATTATATATGTGGTCCCTTGTCGAACTATGCTCTATGTTCTTTTAGATGCAA 6
84 B GTAAATGAGCTATCGCCTCATTTACTCATCGAGACCATCTCCCCCGGAGACGGTACCGGG 2
85 B TAGCTTACCTTAAGATATCTTTGAAATATCGATTTTTCTTGGGTTTACTATATACCAGGC 7
86 B TTAATCTAGTCATCACAATTTTCCACTATCGATAGTGTTGTAAGATGTGTTTGCCTACTC 20
87 B AAACATGAAAGAAAGTAAACATGAAAAATCGAGTTCACAGCTGTGGAAAGAAACTTCACG 2
88 C TACAGAATGTGATGAAAGTGAAAATTATTCGATCTGCTGGAATCATGAAAGTCTAAATTT 21
89 C AAACTTTAAAACAAAATGAAGTTCTAATTCGAACATTCAAATTCCCTAAAGAAAAGAGAG 4
90 C AAGCTTTTTAGTAACATGTTTTTCTTAATCGAATGGTCTGTTCAAGACTATTTTATAGTG 7
91 C AGATTAGTTTCTTATGACATATTCATAGTCGAGATAGAGTATGTAATCATTTTATGATTT 12
92 C TGAGACTAGAGTTATTTTCATCTGATTCTCGAATGTAGCTTACCTACTGCATTTGAAGAA 12
93 C TCTAACCATTATGAGTAGATATTAATCTTCGAGAGCATAAAAATTTCCTTAAACTGATCA 14
94 C TTCATATTTAGGCAGAAAAAAACAGCTTTCGAAGACCAGGACAAGGTACTGTCCCGGAAC 2
95 C CTATTTAAATCAAGGACTTAAAAAGTCCTCGACAAGAGGTATGAAGGTTGAGACCTCTCT 10
96 C ATATATGGCTTTTTAATGGCTGGTAAGATCGACATAAGGATATATAGATCAGAGAAACAT 9
97 C AAAATGTTAATTAGAATTTATTTGGCTTTCGAATGCCTTTTGGGTATCTGTGGGAGAAGT 3
98 C AGGAAAAATATATAGCTAAAGATGTCTCTCGAGGTACTCCAGTTTTTTATTTTTATAATA 1
99 C ATCTTCAGGTCGTATAAATCTTTTGCCTTCGATATATACTGTACATCTCAAGAAATATGT 20
100 C TTTTTTAAAAAAGTTAGTGGATGAGCATTCGAAAAGGGAGATGTCATCTACATTGGTGGC 1
101 C AGATTCTGTGTGTTGCCAGAATCACAACTCGAATGCCTAAAAAGCCTTTATTCTTATAAA 3
102 C AAAACAGCTTCTTTGAAACCCTTTTAAATCGACCTCCCAATTTTTATTTTTATTTTTTTA 11
表9.2e
      探針位置 4 kb 序列位置
編號 群組 起點 1 終點 1 起點 2 終點 2 Chr 起點 1
52 B 31543855 31543884 31591976 31592005 1 31539885
53 B 218948270 218948299 218967856 218967885 2 218948270
54 B 47506512 47506541 47522459 47522488 2 47506512
55 B 22373651 22373680 22479000 22479029 8 22369681
56 B 17395230 17395259 17441052 17441081 21 17395230
57 B 127769658 127769687 127789434 127789463 9 127769658
58 B 242068496 242068525 242136235 242136264 2 242064526
59 B 81728535 81728564 81795688 81795717 1 81724565
60 B 227767543 227767572 227782602 227782631 2 227767543
61 B 494461 494490 562964 562993 6 490491
62 B 16784499 16784528 16819589 16819618 7 16780529
63 B 38329701 38329730 38443614 38443643 20 38329701
64 B 14002834 14002863 14029362 14029391 16 14002834
65 B 125303537 125303566 125348085 125348114 4 125299567
66 B 134271335 134271364 134322258 134322287 6 134267365
67 B 73160991 73161020 73177709 73177738 14 73160991
68 B 60860352 60860381 60904845 60904874 13 60856382
69 B 28511591 28511620 28600364 28600393 2 28511591
70 B 134289631 134289660 134322427 134322456 6 134285661
71 B 14002834 14002863 14029362 14029391 16 14002834
72 B 59229547 59229576 59282114 59282143 15 59225577
73 B 87535061 87535090 87629822 87629851 4 87531091
74 B 29194739 29194768 29221897 29221926 8 29194739
75 B 91735008 91735037 91774654 91774683 1 91731038
76 B 9827713 9827742 9913019 9913048 8 9827713
77 B 7526531 7526560 7606246 7606275 5 7522561
78 B 10464571 10464600 10514161 10514190 19 10460601
79 B 7542352 7542381 7566419 7566448 5 7538382
80 B 53082654 53082683 53104497 53104526 5 53082654
81 B 158588248 158588277 158654908 158654937 7 158584278
82 B 23950676 23950705 24015105 24015134 18 23950676
83 B 111460817 111460846 111524704 111524733 6 111460817
84 B 24012818 24012847 24049866 24049895 2 24008848
85 B 16100508 16100537 16139691 16139720 7 16096538
86 B 57363875 57363904 57379135 57379164 20 57363875
87 B 16713429 16713458 16757017 16757046 2 16713429
88 C 41926861 41926890 41979622 41979651 21 41926861
89 C 152172707 152172736 152243836 152243865 4 152168737
90 C 22502115 22502144 22587352 22587381 7 22502115
91 C 83915554 83915583 83954034 83954063 12 83911584
92 C 82663105 82663134 82704444 82704473 12 82663105
93 C 68327682 68327711 68395524 68395553 14 68323712
94 C 41904274 41904303 41954462 41954491 2 41904274
95 C 50604705 50604734 50654419 50654448 10 50600735
96 C 111941162 111941191 112018014 112018043 9 111937192
97 C 43042541 43042570 43075798 43075827 3 43042541
98 C 83408428 83408457 83452897 83452926 1 83404458
99 C 19876296 19876325 19917737 19917766 20 19872326
100 C 197427799 197427828 197471928 197471957 1 197427799
101 C 120809117 120809146 120844724 120844753 3 120805147
102 C 47467896 47467925 47528616 47528645 11 47463926
表9.2f
      4 kb 序列位置   
編號 群組 終點 1 起點 2 終點 2 探針
52 B 31543884 31588006 31592005 ORF14_1_31540047_31543886_31587537_31592007_FF
53 B 218952269 218967856 218971855 ORF119_2_218948268_218952031_218967854_218969392_RR
54 B 47510511 47522459 47526458 ORF18_2_47506510_47507935_47522457_47530546_RR
55 B 22373680 22475030 22479029 ORF18_8_22370928_22373682_22477274_22479031_FF
56 B 17399229 17441052 17445051 ORF19_21_17395228_17399850_17441050_17442330_RR
57 B 127773657 127789434 127793433 ORF163_9_127769656_127771134_127789432_127791005_RR
58 B 242068525 242132265 242136264 ORF116_2_242067121_242068527_242133611_242136266_FF
59 B 81728564 81795688 81799687 ORF17_1_81722088_81728566_81795686_81801062_FR
60 B 227771542 227778632 227782631 ORF1_2_227767541_227769435_227779837_227782633_RF
61 B 494490 562964 566963 ORF12_6_489302_494492_562962_566609_FR
62 B 16784528 16819589 16823588 ORF106_7_16777840_16784530_16819587_16825123_FR
63 B 38333700 38443614 38447613 ORF19_20_38329699_38336059_38443612_38450633_RR
64 B 14006833 14029362 14033361 ORF15_16_14002832_14006140_14029360_14030604_RR
65 B 125303566 125344115 125348114 ORF13_4_125301039_125303568_125344175_125348116_FF
66 B 134271364 134318288 134322287 ORF14_6_134270140_134271366_134318303_134322289_FF
67 B 73164990 73173739 73177738 ORF158_14_73160989_73163045_73174453_73177740_RF
68 B 60860381 60904845 60908844 ORF156_13_60855031_60860383_60904843_60913572_FR
69 B 28515590 28600364 28604363 ORF1_2_28511589_28516309_28600362_28606396_RR
70 B 134289660 134322427 134326426 ORF19_6_134285274_134289662_134322425_134324942_FR
71 B 14006833 14029362 14033361 ORF145_16_14002832_14006140_14029360_14030604_RR
72 B 59229576 59278144 59282143 ORF12_15_59226397_59229578_59275124_59282145_FF
73 B 87535090 87625852 87629851 ORF127_4_87521130_87535092_87627331_87629853_FF
74 B 29198738 29221897 29225896 ORF10_8_29194737_29197133_29221895_29223912_RR
75 B 91735037 91770684 91774683 ORF102_1_91729836_91735039_91769176_91774685_FF
76 B 9831712 9909049 9913048 ORF12_8_9827711_9830539_9907504_9913050_RF
77 B 7526560 7606246 7610245 ORF182_5_7525226_7526562_7606244_7610178_FR
78 B 10464600 10510191 10514190 ORF11_19_10462371_10464602_10512340_10514192_FF
79 B 7542381 7562449 7566448 ORF107_5_7540900_7542383_7560907_7566450_FF
80 B 53086653 53104497 53108496 ORF19_5_53082652_53086261_53104495_53107169_RR
81 B 158588277 158654908 158658907 ORF146_7_158585412_158588279_158654906_158659127_FR
82 B 23954675 24015105 24019104 ORF10_18_23950674_23952569_24015103_24017541_RR
83 B 111464816 111524704 111528703 ORF160_6_111460815_111466030_111524702_111525757_RR
84 B 24012847 24049866 24053865 ORF14_2_24009691_24012849_24049864_24051131_FR
85 B 16100537 16135721 16139720 ORF153_7_16086203_16100539_16133512_16139722_FF
86 B 57367874 57379135 57383134 ORF140_20_57363873_57366958_57379133_57382850_RR
87 B 16717428 16757017 16761016 ORF159_2_16713427_16718029_16757015_16758385_RR
88 C 41930860 41979622 41983621 ORF19_21_41926859_41930173_41979620_41986582_RR
89 C 152172736 152243836 152247835 ORF171_4_152168385_152172738_152243834_152246201_FR
90 C 22506114 22587352 22591351 ORF14_7_22502113_22509109_22587350_22592472_RR
91 C 83915583 83954034 83958033 ORF13_12_83913616_83915585_83954032_83957600_FR
92 C 82667104 82704444 82708443 ORF104_12_82663103_82673256_82704442_82708010_RR
93 C 68327711 68391554 68395553 ORF139_14_68325745_68327713_68392804_68395555_FF
94 C 41908273 41950492 41954491 ORF15_2_41904272_41908286_41953265_41954493_RF
95 C 50604734 50650449 50654448 ORF107_10_50601158_50604736_50643028_50654450_FF
96 C 111941191 112014044 112018043 ORF131_9_111939947_111941193_112015341_112018045_FF
97 C 43046540 43071828 43075827 ORF168_3_43042539_43050797_43066697_43075829_RF
98 C 83408457 83448927 83452926 ORF13_1_83403878_83408459_83447955_83452928_FF
99 C 19876325 19917737 19921736 ORF19_20_19870175_19876327_19917735_19921318_FR
100 C 197431798 197467958 197471957 ORF105_1_197427797_197435397_197468569_197471959_RF
101 C 120809146 120844724 120848723 ORF17_3_120801777_120809148_120844722_120858831_FR
102 C 47467925 47524646 47528645 ORF16_11_47464161_47467927_47526127_47528647_FF
表9.2g
編號 群組 PCR- 引子 1_ID PCR_ 引子 1 PCR- 引子 2_ID PCR_ 引子 2
52 B OBD159_4173 AACAATGAAAAAAAAAGGTGTTTTT OBD159_4175 AATGAATGCCCAAGTGAAATA
53 B OBD159_4177 CAGTGGAGTTGCTGGGTTATTGGGTA OBD159_4179 ATGTGATTGAGGGTAACTGTGGGACA
54 B OBD159_4181 CCACTGGCATCTCCTCCCTGTTC OBD159_4183 GCAGTCCTATCACTTGGGAGGCT
55 B OBD159_4185 GTCTTTTACTTCAGGGACCCCAGGTGTC OBD159_4187 GCCAACTTTATGGGCAGGCTGTGAGAAT
56 B OBD159_4189 GAAAGCCTCTAACAGTGTCTGGAAGT OBD159_4191 GGATACTAACTGTGCTACTTTGGAGC
57 B OBD159_4193 CAGGCGAGGGTCCCACCAGGCAT OBD159_4195 GCGACTCTGGTTGGTGGACTGCTGGGTG
58 B OBD159_4197 ACTGTGGCCATGAATGGCCCACATT OBD159_4199 AATTTTGGGGTTTATATTTTTGAAAG
59 B OBD159_4201 GAGAAGCCACTAAGCCTACTTTACCTCA OBD159_4203 GCACACAAACCTCCACCACTGTCAACGA
60 B OBD159_4205 CAGTCCCCAGTCTTCCTTGTCCC OBD159_4207 TGTAACTCTCCCCAGGTCACTGC
61 B OBD159_4209 GGCTTCCATCCGTCACTCAGTCCTGTAG OBD159_4211 GGTTTGAGCAGGTGGCATTCCCTTAGCC
62 B OBD159_4213 GTAACAGCAACTTGTCAAACCTAAGCAT OBD159_4215 GAGCACGCACAGACATAAAGATGGGAA
63 B OBD159_4217 CAGCTACACGGGAGGCTGAGGCAG OBD159_4219 ACTCGGGAGACGGAGGTTGCAGTGA
64 B OBD159_4221 CCATTCCTTCCTCCCCACCGAGA OBD159_4223 TGCCATTAGTGAGCACCTCTGGG
65 B OBD159_4225 TGTGTGTGTGTTCACTATTTCTGACTCA OBD159_4227 CTATTATTTGGGATGTCTGGAGTTGAAA
66 B OBD159_4229 GTGGGACTCTGCCAGGTGCGGTGG OBD159_4231 CAAGTTCCCTCAACGCACTAAGCCTCAG
67 B OBD159_4233 CCCCTTAGGATGTTTTAATTTTACC OBD159_4235 GTATTTTTTGTAGAGACGGAGTTTC
68 B OBD159_4237 CTCCCACCTGCCCAGCCTTCAGAGGTT OBD159_4239 GAAAACCAGCACAAGACAAGGATG
69 B OBD159_4241 GATTCAACAAGCTGAAAGAACG OBD159_4243 TACAGCTGTAGGACAAACACATCAT
70 B OBD159_4245 GGATAAGCCTTTACTACTCAGGAAGTGT OBD159_4247 CCCATAATCCCCAGCAGGGTTTCCTAAT
71 B OBD159_4249 CCATTCCTTCCTCCCCACCGAGA OBD159_4251 TGCCATTAGTGAGCACCTCTGGG
72 B OBD159_4253 CCCAGGAAGGGCAGGTGTTGGACAGGC OBD159_4255 GGACACACTGGCATTCCCTATTGGGC
73 B OBD159_4257 CCACACGCAGAATACATCCATCCCAT OBD159_4259 CCTACAAGGATTCTGTCTGACCCTGA
74 B OBD159_4261 GAGGCTGGAGGTTGCAGTGAAGATA OBD159_4263 CTATATATGCCAGGCACAGTGGCTCCCGA
75 B OBD159_4265 TGGACCACAGAACCCTCAGACACCTA OBD159_4267 CACTGTCAGGTTCTCAAATGCCGTTT
76 B OBD159_4269 CGCCCTGCTTGGCAAAGATGTTCCCTGG OBD159_4271 GGGCAACTCGCTTACCCACTCTGTGC
77 B OBD159_4273 CCAGTGTTCGGTAGTATGGTAGGGAA OBD159_4275 GGACATAAGCCCAAACAGGAACACTG
78 B OBD159_4277 GCCCAGGGTAGCATGCAGTGGTGT OBD159_4279 CAGAGACCCGAGTGGCTCCCAGCAG
79 B OBD159_4281 CCTACTCTCCTGATGTTCCAAATGGTCC OBD159_4283 GGAGCAAGGGAAACGGCTACACAGATGT
80 B OBD159_4285 GGGCGGGCAGGATGAATAAGCAGAGC OBD159_4287 TAAAGAAAGGAGCAAGCCAAGGATGCCT
81 B OBD159_4289 TCCCTTCCCTCCCCACTCGCAGG OBD159_4291 CTGCTCAGAAGGAAAGGTGTATTTGTCC
82 B OBD159_4293 TGGGCTACCAGAGACCTACTCAGACTTA OBD159_4295 CGGGAGGGAAAGGACAACGGAGCCG
83 B OBD159_4297 CTGCCATCTCCTATGATAACAGTTCCT OBD159_4299 GCTGGTTGCTGTGAACTACTTTGCTCCA
84 B OBD159_4301 GGAGGGCTGTGGGTAGGCAGGCT OBD159_4303 ACCCTCCACGCCACCTCCGAATCAGACC
85 B OBD159_4305 ACTAAAAGATAACTTTTCCAAATT OBD159_4307 AAAAACTCATTATATAAAGTTTTAA
86 B OBD159_4309 GGCTCCATCACCAGGAAGGTCTG OBD159_4311 CTGGAGAGTGGGTGGGTCTGAAT
87 B OBD159_4313 GCTTCTCCCACACTCCAGGTCAT OBD159_4315 TCATTCCTGCCCTGTGGTCCCCA
88 C OBD159_3401 TTGGGAGTTCTTTCCTTGGGTGTTAC OBD159_3403 TCAAGTCCGTGACACCTGTGGTTTGC
89 C OBD159_3509 CACATAGTTGCTTCTCTTCAAGGTGT OBD159_3511 AAAAGCACACCCAGAATGGCTCCCAC
90 C OBD159_3481 CTGTGATACTAACTGCTGGCGACTCA OBD159_3483 AGGAAGCCCAGATGCTGTGTGGTTTT
91 C OBD159_3465 GAAGAAACTGAGGCTTGCCAAAGTCT OBD159_3467 GCAGAAGCATTCCAGGGTAGAAAACA
92 C OBD159_3385 GGACTTCAAGGAGGTCTCTGGCTTCA OBD159_3387 GCCTGTTTCTACCAGTTTCAGTCTAT
93 C OBD159_3545 GCCAAAGACTCCTCTGGGAATCCAAC OBD159_3547 GAATCCTCCCTTTCCTTTCCTTGATG
94 C OBD159_3405 GCTGAGGAGAGAAGAGCCAGGCAAAT OBD159_3407 CACTAAACCAGTTCAATCCTCGGCTT
95 C OBD159_3505 GTGTTTACTTTGTTCCAGAGGTCACC OBD159_3507 GGAAAGAAAGCAGGATGGAGCAGAGC
96 C OBD159_3521 CTTTCCAGAGAAGGTGTGTGCGTTTC OBD159_3523 GACGCTTTGCCTACTTACAGTTCACC
97 C OBD159_3489 GGAAAAGGCTGACCTACCCAAACCAG OBD159_3491 GCAACACTGTCACAAAATGTCCCACT
98 C OBD159_3393 GGATGGTTGGTTCTCACTTCAGATAA OBD159_3395 CCCAGCACAAGTCTACCACCTTATGC
99 C OBD159_3537 GAAGCAGACTCCACAAACCCTTGGCT OBD159_3539 GCTGTGGACTGGGTAAATAAAGTGTG
100 C OBD159_3553 GGACTGAGGTCTGTGTGGGAGGT OBD159_3555 CTCCAGCACAGCCTTGGGTTACA
101 C OBD159_3529 CGTCAAGGGATGTCAGTGTTTACGCC OBD159_3531 GTCACTGGACTTTTGAATAGCAACAC
102 C OBD159_3425 GCACAGGCAAACGCTCTAAGGGC OBD159_3427 GTGGGAGGACTGTTCATTGAGGC
表9.2h
編號 群組 探針 基因座 Probe_Count_Total
103 C ORF19_7_107580951_107585747_107700145_107705340_RR N/A N/A
104 C ORF1_10_25066818_25068552_25157986_25160553_FF N/A N/A
105 C ORF179_16_73092061_73095486_73111263_73112287_FR N/A N/A
106 C ORF1_X_143596265_143598228_143631538_143634098_RR N/A N/A
107 C ORF16_19_51764536_51772179_51831790_51833005_FR N/A N/A
108 C ORF109_8_103400307_103404391_103472915_103478806_RF N/A N/A
109 C ORF14_20_46567001_46568090_46610481_46612493_FR N/A N/A
110 C ORF19_8_103237571_103240055_103294738_103298438_FR N/A N/A
111 C ORF15_21_17083642_17087491_17108209_17114129_FF N/A N/A
112 C ORF13_1_65337853_65339914_65369795_65373287_RR N/A N/A
113 C ORF143_6_46267215_46269920_46286216_46295988_RF N/A N/A
114 C ORF166_2_38110623_38114294_38180978_38183484_FR N/A N/A
115 C ORF18_1_13945271_13952984_13980703_13983186_FR N/A N/A
116 C ORF13_14_99794535_99796770_99815362_99818414_RF N/A N/A
117 C ORF112_X_147170464_147174350_147220072_147223222_RR N/A N/A
118 C ORF11_10_3161199_3165742_3210550_3216745_RR N/A N/A
119 C ORF14_11_86195747_86200973_86262730_86265020_RF N/A N/A
120 C ORF11_12_83928300_83939202_83954032_83957600_FF N/A N/A
121 C ORF19_5_6164451_6175882_6283431_6289065_FF N/A N/A
122 C ORF142_4_20609595_20612048_20673951_20675409_FR N/A N/A
123 C ORF15_2_78763526_78765449_78779355_78780963_FF N/A N/A
124 C ORF111_20_19844341_19848170_19917735_19921318_FR N/A N/A
125 C ORF168_7_138148315_138155407_138185877_138188419_RR N/A N/A
126 C ORF162_16_89989921_89996258_90038173_90039606_FR N/A N/A
127 C ORF166_2_195495210_195503375_195555062_195566669_RF N/A N/A
128 C ORF163_20_57339344_57344067_57377470_57379133_FF N/A N/A
129 C ORF1_7_41782337_41783687_41851521_41852628_RR N/A N/A
130 C ORF179_11_34425831_34428416_34470619_34472082_RF N/A N/A
131 C ORF11_16_75564971_75566881_75648010_75649086_RR N/A N/A
132 C ORF11_13_99298431_99304510_99339091_99345466_FR N/A N/A
133 C ORF1_16_51556847_51564565_51623942_51626175_RR N/A N/A
134 C ORF101_20_19870175_19876327_19898126_19900554_FR N/A N/A
135 C ORF111_2_200446136_200455550_200507238_200513664_FR N/A N/A
136 C ORF13_10_25066818_25068552_25120749_25126820_FR N/A N/A
137 C ORF109_9_28333777_28339631_28371887_28374860_FF N/A N/A
138 C ORF122_8_31175232_31178937_31205589_31213041_FR N/A N/A
139 C ORF15_9_96188932_96193703_96234157_96237688_FF N/A N/A
140 C ORF197_10_106496977_106502145_106531472_106538179_RF N/A N/A
141 C ORF105_14_52585153_52587568_52649397_52652795_RR N/A N/A
142 C ORF177_6_157189218_157193153_157237058_157240060_RF N/A N/A
143 C ORF15_2_39587442_39588976_39623225_39627003_RR N/A N/A
144 C ORF13_16_14002832_14006140_14029360_14030604_RR N/A N/A
145 C ORF11_2_39587442_39588976_39657947_39666343_RR N/A N/A
146 C ORF1_10_96688596_96696898_96748228_96749907_FR N/A N/A
147 C ORF124_11_104895593_104903291_104942780_104952074_RR N/A N/A
148 C ORF197_10_93371665_93374909_93410956_93413925_RR N/A N/A
149 B ORF16_16_13994577_13998645_14029360_14030604_RR N/A N/A
150 B ORF15_2_19298458_19304309_19333103_19336336_RR N/A N/A
151 B ORF10_8_104312502_104316292_104372432_104376137_FF N/A N/A
152 B ORF1_10_25066818_25068552_25120749_25126820_FF N/A N/A
153 B ORF128_2_177170392_177174097_177302614_177307613_FR N/A N/A
表9.3a
編號 群組 Probe_Count_Sig HyperG_Stats FDR_HyperG Percent_Sig logFC AveExpr
103 C N/A N/A N/A N/A -0.580384316 -0.580384316
104 C N/A N/A N/A N/A -0.579795406 -0.579795406
105 C N/A N/A N/A N/A -0.57645549 -0.57645549
106 C N/A N/A N/A N/A -0.575761869 -0.575761869
107 C N/A N/A N/A N/A -0.5704231 -0.5704231
108 C N/A N/A N/A N/A -0.569099158 -0.569099158
109 C N/A N/A N/A N/A -0.567902229 -0.567902229
110 C N/A N/A N/A N/A -0.567643608 -0.567643608
111 C N/A N/A N/A N/A -0.56761609 -0.56761609
112 C N/A N/A N/A N/A -0.567337152 -0.567337152
113 C N/A N/A N/A N/A -0.566513296 -0.566513296
114 C N/A N/A N/A N/A -0.562334554 -0.562334554
115 C N/A N/A N/A N/A -0.561180836 -0.561180836
116 C N/A N/A N/A N/A -0.560245549 -0.560245549
117 C N/A N/A N/A N/A -0.559624498 -0.559624498
118 C N/A N/A N/A N/A -0.557407963 -0.557407963
119 C N/A N/A N/A N/A -0.556319829 -0.556319829
120 C N/A N/A N/A N/A -0.556012217 -0.556012217
121 C N/A N/A N/A N/A -0.550953623 -0.550953623
122 C N/A N/A N/A N/A -0.550934981 -0.550934981
123 C N/A N/A N/A N/A -0.547738866 -0.547738866
124 C N/A N/A N/A N/A -0.547460918 -0.547460918
125 C N/A N/A N/A N/A -0.547355026 -0.547355026
126 C N/A N/A N/A N/A -0.546619831 -0.546619831
127 C N/A N/A N/A N/A -0.546571867 -0.546571867
128 C N/A N/A N/A N/A -0.546225009 -0.546225009
129 C N/A N/A N/A N/A -0.545327451 -0.545327451
130 C N/A N/A N/A N/A -0.543525543 -0.543525543
131 C N/A N/A N/A N/A -0.5428455 -0.5428455
132 C N/A N/A N/A N/A -0.542118117 -0.542118117
133 C N/A N/A N/A N/A -0.542064981 -0.542064981
134 C N/A N/A N/A N/A -0.541750489 -0.541750489
135 C N/A N/A N/A N/A -0.536534545 -0.536534545
136 C N/A N/A N/A N/A -0.534704622 -0.534704622
137 C N/A N/A N/A N/A -0.534170568 -0.534170568
138 C N/A N/A N/A N/A -0.533764016 -0.533764016
139 C N/A N/A N/A N/A -0.53216689 -0.53216689
140 C N/A N/A N/A N/A -0.531944176 -0.531944176
141 C N/A N/A N/A N/A -0.531556709 -0.531556709
142 C N/A N/A N/A N/A -0.524769731 -0.524769731
143 C N/A N/A N/A N/A -0.52447916 -0.52447916
144 C N/A N/A N/A N/A -0.524161019 -0.524161019
145 C N/A N/A N/A N/A -0.522994657 -0.522994657
146 C N/A N/A N/A N/A -0.522456247 -0.522456247
147 C N/A N/A N/A N/A -0.522415272 -0.522415272
148 C N/A N/A N/A N/A -0.522311741 -0.522311741
149 B N/A N/A N/A N/A -0.52076089 -0.52076089
150 B N/A N/A N/A N/A -0.520350999 -0.520350999
151 B N/A N/A N/A N/A -0.520217634 -0.520217634
152 B N/A N/A N/A N/A -0.519498584 -0.519498584
153 B N/A N/A N/A N/A -0.518845627 -0.518845627
表9.3b
編號 群組 t P值 adj.P.Val B FC
103 C -10.00265062 0.000000374 0.0000405 7.045948025 0.668785598
104 C -11.33939514 0.0000000954 0.0000179 8.404971577 0.669058652
105 C -8.286460787 0.00000271 0.000139101 5.04055063 0.670609353
106 C -6.252927722 0.0000434 0.000829019 2.201533666 0.670931847
107 C -5.792734053 0.0000875 0.001335671 1.479974689 0.673419265
108 C -6.040396591 0.0000598 0.001031804 1.872060278 0.674037537
109 C -8.299217518 0.00000267 0.000137526 5.056678015 0.674596983
110 C -7.531499725 0.00000716 0.000253765 4.050316707 0.674717924
111 C -3.833775368 0.002401501 0.013479024 -1.906757953 0.674730794
112 C -5.920788535 0.0000718 0.001166281 1.683799077 0.674861262
113 C -3.723118962 0.002935801 0.015401869 -2.109702831 0.675246754
114 C -9.974271127 0.000000385 0.0000414 7.015301538 0.67720543
115 C -5.013112028 0.00030752 0.003198461 0.189152517 0.677747205
116 C -4.940505936 0.000347203 0.003484861 0.064709444 0.678186726
117 C -4.593530372 0.00062628 0.00526829 -0.539218116 0.678478734
118 C -6.214160763 0.0000460 0.000862205 2.141916694 0.67952194
119 C -5.930971965 0.0000707 0.001154102 1.699907371 0.680034654
120 C -6.525847027 0.0000290 0.000637435 2.615192535 0.680179666
121 C -5.680600812 0.000104299 0.001504687 1.299568985 0.682568801
122 C -6.017675982 0.0000619 0.00105584 1.836455913 0.68257762
123 C -7.594334912 0.00000658 0.000240229 4.135487936 0.684091464
124 C -5.090238268 0.000270538 0.002921847 0.320580403 0.684223273
125 C -12.15310973 0.0000000444 0.0000120 9.158075035 0.684273496
126 C -2.919821116 0.012907869 0.04460444 -3.586971358 0.68462229
127 C -3.892386869 0.002160086 0.012450674 -1.799543239 0.684645051
128 C -7.020143452 0.0000143 0.000399805 3.337793784 0.684809676
129 C -5.052407248 0.000288057 0.003052081 0.256212894 0.685235856
130 C -4.884054488 0.000381754 0.003716269 -0.032519331 0.686092242
131 C -2.759734453 0.017361564 0.054595701 -3.877268266 0.686415721
132 C -6.774152812 0.0000203 0.000504048 2.982425251 0.686761888
133 C -8.732503168 0.00000158 0.0000989 5.593040606 0.686787182
134 C -7.248122137 0.0000105 0.000325384 3.6597719 0.686936911
135 C -10.01824655 0.000000367 0.0000402 7.062756258 0.689424969
136 C -7.729829234 0.00000551 0.000216233 4.317411465 0.690299995
137 C -5.36337655 0.000173007 0.002142814 0.779549515 0.690555576
138 C -10.56605661 0.000000207 0.0000289 7.638430717 0.690750202
139 C -7.601300089 0.00000652 0.000238935 4.144897502 0.691515316
140 C -3.955401325 0.001928261 0.011499225 -1.684522551 0.691622076
141 C -8.15996529 0.00000318 0.000153403 4.879569025 0.691807851
142 C -6.889004942 0.0000172 0.000452456 3.149382339 0.695070041
143 C -6.412416451 0.0000342 0.000711704 2.444550132 0.695210049
144 C -4.429987328 0.000831579 0.006401704 -0.828840478 0.695363372
145 C -4.461922671 0.000786579 0.006157605 -0.772051332 0.695925773
146 C -7.396670725 0.00000857 0.000286972 3.865820271 0.69618554
147 C -7.159624596 0.0000118 0.000352082 3.535618488 0.696205313
148 C -7.046263262 0.0000138 0.000390254 3.375040231 0.696255276
149 B -4.940213927 0.000347373 0.00348576 0.064207565 0.69700413
150 B -6.676578229 0.0000233 0.0005504 2.839145562 0.697202188
151 B -8.649455976 0.00000174 0.000105182 5.491929731 0.697266641
152 B -6.284477315 0.0000414 0.000805255 2.249893478 0.69761425
153 B -5.014612232 0.000306752 0.003191623 0.191716487 0.697930059
表9.3c
編號 群組 FC_1 LS 偵測到之環
103 C -1.495247511 -1 輕度自閉症
104 C -1.494637274 -1 輕度自閉症
105 C -1.491181111 -1 輕度自閉症
106 C -1.49046435 -1 輕度自閉症
107 C -1.484959002 -1 輕度自閉症
108 C -1.483596899 -1 輕度自閉症
109 C -1.482366547 -1 輕度自閉症
110 C -1.482100838 -1 輕度自閉症
111 C -1.482072568 -1 輕度自閉症
112 C -1.481786044 -1 輕度自閉症
113 C -1.480940107 -1 輕度自閉症
114 C -1.476656795 -1 輕度自閉症
115 C -1.47547639 -1 輕度自閉症
116 C -1.474520161 -1 輕度自閉症
117 C -1.473885547 -1 輕度自閉症
118 C -1.47162283 -1 輕度自閉症
119 C -1.470513296 -1 輕度自閉症
120 C -1.470199786 -1 輕度自閉症
121 C -1.465053778 -1 輕度自閉症
122 C -1.465034847 -1 輕度自閉症
123 C -1.461792834 -1 輕度自閉症
124 C -1.461511234 -1 輕度自閉症
125 C -1.461403965 -1 輕度自閉症
126 C -1.460659424 -1 輕度自閉症
127 C -1.460610865 -1 輕度自閉症
128 C -1.460259741 -1 輕度自閉症
129 C -1.459351538 -1 輕度自閉症
130 C -1.457529964 -1 輕度自閉症
131 C -1.45684309 -1 輕度自閉症
132 C -1.456108759 -1 輕度自閉症
133 C -1.45605513 -1 輕度自閉症
134 C -1.455737761 -1 輕度自閉症
135 C -1.450484164 -1 輕度自閉症
136 C -1.448645527 -1 輕度自閉症
137 C -1.448109371 -1 輕度自閉症
138 C -1.44770135 -1 輕度自閉症
139 C -1.446099569 -1 輕度自閉症
140 C -1.445876346 -1 輕度自閉症
141 C -1.445488077 -1 輕度自閉症
142 C -1.43870393 -1 輕度自閉症
143 C -1.438414192 -1 輕度自閉症
144 C -1.438097029 -1 輕度自閉症
145 C -1.436934855 -1 輕度自閉症
146 C -1.436398694 -1 輕度自閉症
147 C -1.436357899 -1 輕度自閉症
148 C -1.436254826 -1 輕度自閉症
149 B -1.434711728 -1 輕度自閉症
150 B -1.434304163 -1 輕度自閉症
151 B -1.43417158 -1 輕度自閉症
152 B -1.433456956 -1 輕度自閉症
153 B -1.432808327 -1 輕度自閉症
表9.3d
      探針序列 探針位置
編號 群組 60 mer Chr
103 C CGTTAGGTGAGTTTATTTTCAAAGACTTTCGATGGTTTTAAAAAATGTATCAAGTCCACA 7
104 C TGATTTACTTTAAAATACTTTCGTGCAATCGATGTCCTAGTTTTTGTACTAGGTGGTGGA 10
105 C AATGTATTGCTGCTGAAACATTAACCTTTCGATTCTGCTTTTGTTTTTGTTTTTTCCCTT 16
106 C ATATAGTACAAACATATATTAATGGTAATCGAGTTTGTACCACAAAGCCATTTTGATTAG X
107 C CACCACCAATAAACATTTCTAGACTTGCTCGATTATGTTAGTAATTACACTAGTAATATC 19
108 C ATGCTATGTCTCTTTTATTTTTAACTTCTCGAATATGAGCCATGTTTCTATGCAGAATTC 8
109 C GCTTACTCAGAACTTAAAAATTTCATAATCGAACCTCCTTCTGGCCAAAGAGACTTTTCA 20
110 C TTCTAAAACAGTTTTTTATTTGAGATCTTCGATTTTAACTTGGAGAAACTTTGCTCTGCT 8
111 C CAGCAAGCAATAATGTACATAATATAACTCGACTTTCTTAAAAGGCGTGTATATTCAAAA 21
112 C GTAAGAATACTGATGTCCCTCTATATACTCGATTCACTTTTATGCTTAGAAGCCACATTG 1
113 C TTTTTTTTTTTTTTAACAGCAATGTTCATCGAAAGGAATAATGTTGTTCTTTTTAGAAAA 6
114 C TATAAATACCAGAGAAGAAGCCATATTTTCGAAGGGCATGAACATTTTTATGACTCTTGG 2
115 C TACATTTTTAGCTCATCATAAAAGATATTCGATACACCAAGCAGACAAAATTCTGGCTTG 1
116 C ATATTTAATGTCCTATATCTGCAGATATTCGACACCTGTTTGTCACTGTAGCAGTAAAGA 14
117 C AACTTTAAAATTTAATTACTGTTACTATTCGATAAATATGATACTCCTCTCCACTTACTT X
118 C ACATCTAGATGAAGTTTAAAATGTAAGATCGACAGACCTTGCACATTTGTATGCGAAGTC 10
119 C GATTCCTTTGTGAGAATCATACCTTCCTTCGACAATGGGTTATTCAGGAATTTAAACTTT 11
120 C AAGAAAATTTTTTCTCTAAGCACTCTGATCGATGAATCAACATTTTCCAAAATAATACAT 12
121 C CTCTGCTTCCCTTTATTTACATCATTAGTCGATATAACTGGATGAATATCTACTGTTTTT 5
122 C TTCATTAGAATCCACTTCATTAAATCTTTCGAAGATGGGATACTATTGACAAGGGGTCAC 4
123 C CTATATTGTAGCTCTATTTTCTCTAAATTCGAACACTCTTGTCTTGCCCTCATTTGAGCC 2
124 C GTTAAGTGGTGTACTTTTTGAAAATCCATCGATATATACTGTACATCTCAAGAAATATGT 20
125 C TAAGCCAGTTTAATTGAATAACGAATCCTCGACATATCTCTTTCAGGGACATTCAAATCA 7
126 C ACATTCAGCTATAAAAAGGAATAAAGTATCGAGAGCTCACCTCTGAAAGCACATGAGGGA 16
127 C CTAGTTTCCCTAGAGCTTACTGATAATCTCGAAGAGGAAAATTTTTCAGACATTAATTTG 2
128 C TGATAATATTATTTATTTGAAAAGTTTCTCGATACTAGAATTTTACACTCAGCAAGTCAG 20
129 C TTCAATTTTGGTCAATTTATTTCAACCATCGAAACTTTCCAAATTCATTTGTTTAAATCT 7
130 C TAAGAACAGAGATGGTATTTTCTTTCTTTCGATTGAGTAGTTTCACTGAGGGGGTACAAA 11
131 C CATCATTTCCTACACTGGAAATTCCTGATCGACGCTCATCCTGCACGGCGGCGGCACCGT 16
132 C ATTTCTTGTATCTCTAGGTGATGTATGATCGACCTTTTCCTTGAGTTCTAGAATTACATA 13
133 C TCTCTCTGATGCATCTGCTTTGGATAGGTCGAGCTGTTTTTTTCTGAAGGCAATTTATTG 16
134 C ATCTTCAGGTCGTATAAATCTTTTGCCTTCGAACAGAAATTCCTTTTCATATTTTCAAAA 20
135 C TGCACTCAGAAAGTGATCAGCTCACATTTCGAGATATGCTAAGAAGTTGGAAAATGTTGG 2
136 C TGATTTACTTTAAAATACTTTCGTGCAATCGAGTAACATGCTTCTTGATATCAACAGTCT 10
137 C GCCCACTAAATAGTAATATTAGGATCTATCGAGGTGGGTCAATTTGTCAAATTAAAAGAA 9
138 C TTACTACAATTACTATATTCTATTAATATCGAGGGAAACCTACTCTCTCTTCAAGGCCAA 8
139 C TTGCAGACTAGAATTCATCCAAAACTTTTCGAGTTTGCCAGGATTTAGAAAGATCATTGT 9
140 C TCATTTTACCGAGTGTAAATTGTTGTTTTCGACTCCATTTCGCTTCTAACCTCTGAGCTG 10
141 C ATATAGTATGGATTCTGATATTTTGATATCGATGTTTACCAGAAACTGCTTTTTAAAAAA 14
142 C GTCCTAATATTTTATACATAAACCAGTTTCGAGTTGATGCACAAAAATTTTCATCCCATT 6
143 C ACTATTTTTAAGTGCACAGTTTAACAATTCGATTCAGCTGGGGAAAAATGAAAATAACAA 2
144 C TCTTAATTTGATTTTCTCTGGCTCAGAATCGAGATATTACACTCCAGCCTGGGTGACGGA 16
145 C ACTATTTTTAAGTGCACAGTTTAACAATTCGAGAATTGAAGACAAAATCAGAGTGGTCCA 2
146 C CCTTGATAGGATTTGGAAAAATATTAGATCGAAAACAGAAAGCAGATAAGGATTCCCATC 10
147 C TCTTTTTTAGACAACTGTTTATTAGCAGTCGAAAATCCAGTTAGCTTCCTCCACTTCATT 11
148 C TACCTATGAATATTTACTATAATAGAGATCGAGCTATGTGAGTCTGAGTAAGTTTCTTAA 10
149 B GCAGGTGAGTCAGACTTTGGGATTCAGTTCGAGATATTACACTCCAGCCTGGGTGACGGA 16
150 B CTTTCCCTGATTAATTACTTTCTAGTAATCGATGAATGAATGAATGAAGCCAAGGAAAAT 2
151 B ACCTGATGCTATCTTTAAGTGGCAGACATCGACTGTTCTTCTCTTTCTATGGGGAAGTTC 8
152 B TGATTTACTTTAAAATACTTTCGTGCAATCGATAATAATAATAACCATTAATTGGGCAGG 10
153 B ATCTCTAAAATTGATAAATTGCTGCTTATCGAGTTTGGTTCAGCAGAGCTTTCTGTAAAG 2
表9.3e
      探針位置 4 kb 序列位置
編號 群組 起點 1 終點 1 起點 2 終點 2 Chr 起點 1
103 C 107580953 107580982 107700147 107700176 7 107580953
104 C 25068521 25068550 25160522 25160551 10 25064551
105 C 73095455 73095484 73111265 73111294 16 73091485
106 C 143596267 143596296 143631540 143631569 X 143596267
107 C 51772148 51772177 51831792 51831821 19 51768178
108 C 103400309 103400338 103478775 103478804 8 103400309
109 C 46568059 46568088 46610483 46610512 20 46564089
110 C 103240024 103240053 103294740 103294769 8 103236054
111 C 17087460 17087489 17114098 17114127 21 17083490
112 C 65337855 65337884 65369797 65369826 1 65337855
113 C 46267217 46267246 46295957 46295986 6 46267217
114 C 38114263 38114292 38180980 38181009 2 38110293
115 C 13952953 13952982 13980705 13980734 1 13948983
116 C 99794537 99794566 99818383 99818412 14 99794537
117 C 147170466 147170495 147220074 147220103 X 147170466
118 C 3161201 3161230 3210552 3210581 10 3161201
119 C 86195749 86195778 86264989 86265018 11 86195749
120 C 83939171 83939200 83957569 83957598 12 83935201
121 C 6175851 6175880 6289034 6289063 5 6171881
122 C 20612017 20612046 20673953 20673982 4 20608047
123 C 78765418 78765447 78780932 78780961 2 78761448
124 C 19848139 19848168 19917737 19917766 20 19844169
125 C 138148317 138148346 138185879 138185908 7 138148317
126 C 89996227 89996256 90038175 90038204 16 89992257
127 C 195495212 195495241 195566638 195566667 2 195495212
128 C 57344036 57344065 57379102 57379131 20 57340066
129 C 41782339 41782368 41851523 41851552 7 41782339
130 C 34425833 34425862 34472051 34472080 11 34425833
131 C 75564973 75565002 75648012 75648041 16 75564973
132 C 99304479 99304508 99339093 99339122 13 99300509
133 C 51556849 51556878 51623944 51623973 16 51556849
134 C 19876296 19876325 19898128 19898157 20 19872326
135 C 200455519 200455548 200507240 200507269 2 200451549
136 C 25068521 25068550 25120751 25120780 10 25064551
137 C 28339600 28339629 28374829 28374858 9 28335630
138 C 31178906 31178935 31205591 31205620 8 31174936
139 C 96193672 96193701 96237657 96237686 9 96189702
140 C 106496979 106497008 106538148 106538177 10 106496979
141 C 52585155 52585184 52649399 52649428 14 52585155
142 C 157189220 157189249 157240029 157240058 6 157189220
143 C 39587444 39587473 39623227 39623256 2 39587444
144 C 14002834 14002863 14029362 14029391 16 14002834
145 C 39587444 39587473 39657949 39657978 2 39587444
146 C 96696867 96696896 96748230 96748259 10 96692897
147 C 104895595 104895624 104942782 104942811 11 104895595
148 C 93371667 93371696 93410958 93410987 10 93371667
149 B 13994579 13994608 14029362 14029391 16 13994579
150 B 19298460 19298489 19333105 19333134 2 19298460
151 B 104316261 104316290 104376106 104376135 8 104312291
152 B 25068521 25068550 25126789 25126818 10 25064551
153 B 177174066 177174095 177302616 177302645 2 177170096
表9.3f
      4 kb 序列位置   
編號 群組 終點 1 起點 2 終點 2 探針
103 C 107584952 107700147 107704146 ORF19_7_107580951_107585747_107700145_107705340_RR
104 C 25068550 25156552 25160551 ORF1_10_25066818_25068552_25157986_25160553_FF
105 C 73095484 73111265 73115264 ORF179_16_73092061_73095486_73111263_73112287_FR
106 C 143600266 143631540 143635539 ORF1_X_143596265_143598228_143631538_143634098_RR
107 C 51772177 51831792 51835791 ORF16_19_51764536_51772179_51831790_51833005_FR
108 C 103404308 103474805 103478804 ORF109_8_103400307_103404391_103472915_103478806_RF
109 C 46568088 46610483 46614482 ORF14_20_46567001_46568090_46610481_46612493_FR
110 C 103240053 103294740 103298739 ORF19_8_103237571_103240055_103294738_103298438_FR
111 C 17087489 17110128 17114127 ORF15_21_17083642_17087491_17108209_17114129_FF
112 C 65341854 65369797 65373796 ORF13_1_65337853_65339914_65369795_65373287_RR
113 C 46271216 46291987 46295986 ORF143_6_46267215_46269920_46286216_46295988_RF
114 C 38114292 38180980 38184979 ORF166_2_38110623_38114294_38180978_38183484_FR
115 C 13952982 13980705 13984704 ORF18_1_13945271_13952984_13980703_13983186_FR
116 C 99798536 99814413 99818412 ORF13_14_99794535_99796770_99815362_99818414_RF
117 C 147174465 147220074 147224073 ORF112_X_147170464_147174350_147220072_147223222_RR
118 C 3165200 3210552 3214551 ORF11_10_3161199_3165742_3210550_3216745_RR
119 C 86199748 86261019 86265018 ORF14_11_86195747_86200973_86262730_86265020_RF
120 C 83939200 83953599 83957598 ORF11_12_83928300_83939202_83954032_83957600_FF
121 C 6175880 6285064 6289063 ORF19_5_6164451_6175882_6283431_6289065_FF
122 C 20612046 20673953 20677952 ORF142_4_20609595_20612048_20673951_20675409_FR
123 C 78765447 78776962 78780961 ORF15_2_78763526_78765449_78779355_78780963_FF
124 C 19848168 19917737 19921736 ORF111_20_19844341_19848170_19917735_19921318_FR
125 C 138152316 138185879 138189878 ORF168_7_138148315_138155407_138185877_138188419_RR
126 C 89996256 90038175 90042174 ORF162_16_89989921_89996258_90038173_90039606_FR
127 C 195499211 195562668 195566667 ORF166_2_195495210_195503375_195555062_195566669_RF
128 C 57344065 57375132 57379131 ORF163_20_57339344_57344067_57377470_57379133_FF
129 C 41786338 41851523 41855522 ORF1_7_41782337_41783687_41851521_41852628_RR
130 C 34429832 34468081 34472080 ORF179_11_34425831_34428416_34470619_34472082_RF
131 C 75568972 75648012 75652011 ORF11_16_75564971_75566881_75648010_75649086_RR
132 C 99304508 99339093 99343092 ORF11_13_99298431_99304510_99339091_99345466_FR
133 C 51560848 51623944 51627943 ORF1_16_51556847_51564565_51623942_51626175_RR
134 C 19876325 19898128 19902127 ORF101_20_19870175_19876327_19898126_19900554_FR
135 C 200455548 200507240 200511239 ORF111_2_200446136_200455550_200507238_200513664_FR
136 C 25068550 25120751 25124750 ORF13_10_25066818_25068552_25120749_25126820_FR
137 C 28339629 28370859 28374858 ORF109_9_28333777_28339631_28371887_28374860_FF
138 C 31178935 31205591 31209590 ORF122_8_31175232_31178937_31205589_31213041_FR
139 C 96193701 96233687 96237686 ORF15_9_96188932_96193703_96234157_96237688_FF
140 C 106500978 106534178 106538177 ORF197_10_106496977_106502145_106531472_106538179_RF
141 C 52589154 52649399 52653398 ORF105_14_52585153_52587568_52649397_52652795_RR
142 C 157193219 157236059 157240058 ORF177_6_157189218_157193153_157237058_157240060_RF
143 C 39591443 39623227 39627226 ORF15_2_39587442_39588976_39623225_39627003_RR
144 C 14006833 14029362 14033361 ORF13_16_14002832_14006140_14029360_14030604_RR
145 C 39591443 39657949 39661948 ORF11_2_39587442_39588976_39657947_39666343_RR
146 C 96696896 96748230 96752229 ORF1_10_96688596_96696898_96748228_96749907_FR
147 C 104899594 104942782 104946781 ORF124_11_104895593_104903291_104942780_104952074_RR
148 C 93375666 93410958 93414957 ORF197_10_93371665_93374909_93410956_93413925_RR
149 B 13998578 14029362 14033361 ORF16_16_13994577_13998645_14029360_14030604_RR
150 B 19302459 19333105 19337104 ORF15_2_19298458_19304309_19333103_19336336_RR
151 B 104316290 104372136 104376135 ORF10_8_104312502_104316292_104372432_104376137_FF
152 B 25068550 25122819 25126818 ORF1_10_25066818_25068552_25120749_25126820_FF
153 B 177174095 177302616 177306615 ORF128_2_177170392_177174097_177302614_177307613_FR
表9.3g
編號 群組 PCR- 引子 1_ID PCR_ 引子 1 PCR- 引子 2_ID PCR_ 引子 2
103 C OBD159_3421 CTGAGACAAGGCAGGGCAGGTGT OBD159_3423 GCCTATTCCTGATTGGACCCCAG
104 C OBD159_3557 GTATCTCACGCACACAAAGGGACACT OBD159_3559 CCTTCCTTTCCCTTCCCTTTCTGTTC
105 C OBD159_3565 AGACATCCCACACCCATCTTGCCTCT OBD159_3567 GATTGTTAGACCTCCCATTAGTGTGT
106 C OBD159_3469 GCAGTAACAGACCCAAGGGCATAATA OBD159_3471 CCTCCCATTTCCATCCTCCAGTGAAC
107 C OBD159_3589 CTGAGGATTCTTGGTGTTTATGGGAC OBD159_3591 CGTCAAAGGCTCTCAGACCAGCAAAG
108 C OBD159_3381 TTTCTCTACCCTTTATCTACCTCCTA OBD159_3383 AGCCTGCTGTATTACCTTTGTGGT
109 C OBD159_3497 ATGCTCAATGCTGTCCCCTGGTG OBD159_3499 AGCAACACCGCCTCCACTGCCAT
110 C OBD159_3517 CATACCCAGCAGTGTGACAAGGC OBD159_3519 GGCAGTGGCTTGCTCTGTGTCCT
111 C OBD159_3457 CTCTGCCCAGGAGCACAGTAATGAAG OBD159_3459 TACCCTATTGCTGGAGGAGATGAAAA
112 C OBD159_3581 ATGAGCCTGGAACATCTGGTGATACC OBD159_3583 CGCTTTTGAATGCTGGGCTATGTGCT
113 C OBD159_3641 GGAAGCAAGGAAGTAGGCTATGGAAC OBD159_3643 GTGAACCACCATACCGACCCTCTTTA
114 C OBD159_3413 TGTGAAGGGCAGTGAATAAAGGATTA OBD159_3415 GGCGTCAGTGTAAACAAATCAAGTCA
115 C OBD159_3409 TGCTGTGTGACCTTGGGATGTCC OBD159_3411 CAGAAAGATGCCAGTGAGCCCAGC
116 C OBD159_3621 CCAAACCAAGGAGGTGACAATGGAGG OBD159_3623 CCACTACAGAGGATGAATCAACACAC
117 C OBD159_3525 AGGCAGGCAGTCCAGAGATGTGC OBD159_3527 GGAACAAAGCCCTGCCAATGCCT
118 C OBD159_3445 CTGGATTCTCTCAACCCCGAGTGTGT OBD159_3447 AACAGCAGAAGTCCAGTAGAAGTTGG
119 C OBD159_3417 CCATTCTCTTTGGGTGGCGTGGTAT OBD159_3419 CTTTGAGAAGTTGGTCCACATACTGC
120 C OBD159_3501 GAAGGATTTGAGTTCAGAGGAATGGA OBD159_3503 GGAAACTGAAACCGTAACAAGGAACA
121 C OBD159_3441 CCTCTGGTATCTTTGGTCACTGTGGA OBD159_3443 GCTCAATAAAGCAAAAGACAGCAGAA
122 C OBD159_3613 AAGGGAACAAATCTAAGTGCTGTGGC OBD159_3615 GCCGCATAGAGAAATGAGTGGAGGGT
123 C OBD159_3493 GAACTACTCTTTGTGTTATCTTGGTC OBD159_3495 ATTGCTTGGGATGTTTTGAGGCTC
124 C OBD159_3617 GGGACATTGAGGTGTTGGTGGCATTC OBD159_3619 GCTGTGGACTGGGTAAATAAAGTGTG
125 C OBD159_3633 ACTGGTAAAATCTGAGAAAAGACAGC OBD159_3635 CAAGGTGAAGTCTGGAGGGAAAGAGA
126 C OBD159_3645 GTCCTTCAGCAGGGATGAGTCTG OBD159_3647 TGTGAGGACCAGCACTGAGCAGC
127 C OBD159_3549 AATACTGGCAAGAACCCATCTACTGC OBD159_3551 GAAGAGTTGGGAACATTATCCTAAGG
128 C OBD159_3433 GATTGATGTAGTCTTCAGTGTTTTGC OBD159_3435 GGGTCTGTCACTGTATTTCTCACCTG
129 C OBD159_3573 CCTGAGTGGCAAGTTGTTGGAGACAT OBD159_3575 GGAGGCAGAGTGAATAAAGGGTTGGT
130 C OBD159_3437 CATCAGAAGATAACTTGAGCACCGTC OBD159_3439 GCCTGTGGACTCTTTCCTCTCTATCC
131 C OBD159_3585 AAGGCAGTCTGGTCTGGGTCACC OBD159_3587 GTGGAGATGAAATCACCCGAGGC
132 C OBD159_3605 CCTCTGAAAGGCAGTGTGGGTGT OBD159_3607 GCTACTGAGTGGGCAGGTGGCTA
133 C OBD159_3429 CAGGGTTGCCTTGGGTTAGGGTT OBD159_3431 AGTGAGGAAAGCCCTGGACTCCC
134 C OBD159_3541 GCAGACTCCACAAACCCTTGGCT OBD159_3543 GAAGTCCCCTGGCGAAGATGAGC
135 C OBD159_3477 AAGGCACTGGCACTCTACCTAATGTG OBD159_3479 GCCTCTCCTTTGTTTGCTGTGTGACA
136 C OBD159_3473 TATCTCACGCACACAAAGGGACACTT OBD159_3475 CAGAGCCATTCAAGGAGCCAAAAGGC
137 C OBD159_3513 GTCCAGTAGTATGGTGGCTGTGAATA OBD159_3515 CCAGAGCCCCAAATAAGGATGGAAGC
138 C OBD159_3461 CCCTGCCATTTGAAAGGTATTTGCCT OBD159_3463 CTACAACCAAGATGCTAAGACAGTTT
139 C OBD159_3629 GACCACAGGTATGCTGGGAATCC OBD159_3631 AGGGCGTGCTATCTTTGCCTGGC
140 C OBD159_3561 CCACACACACAGAAAACTCAAGGCTG OBD159_3563 GCTTGTTCTACACCCAGGAATGACCA
141 C OBD159_3601 GAGAGCGAGAGCAAGAGAGAGTTAGT OBD159_3603 GGTAGAGAGTCTTGATGTAACAGAAT
142 C OBD159_3569 AATCAATCTCCTCTGGTCGCTCCCAC OBD159_3571 GGCTTTAGGCAGAAGAGTGTTCATTC
143 C OBD159_3609 GCTATTCAGTTCCTACATCTTATTCC OBD159_3611 CTGGCTACTCTTGAAACACCCACTTG
144 C OBD159_3597 CCATTCCTTCCTCCCCACCGAGA OBD159_3599 TGCCATTAGTGAGCACCTCTGGG
145 C OBD159_3577 GCTATTCAGTTCCTACATCTTATTCC OBD159_3579 GATTCCCATTGTCAAGACCAGGAGAC
146 C OBD159_3593 CCCCATTATCTTTCTATGAACCCACA OBD159_3595 CGTGTGTGAATGACTCTTTGTGCTTG
147 C OBD159_3625 CAAGAGCAAGGACCCTGAGACAG OBD159_3627 CACAAGCAGCCCAGCCCTCCTTA
148 C OBD159_3533 TGGGAGAGGAGACAAAGGCACCT OBD159_3535 CCAGATACTGTGCTAAAGGCTTCGCC
149 B OBD159_4317 CGTGCTAAACGGATGTTCTCGGG OBD159_4319 CTGCCATTAGTGAGCACCTCTGGG
150 B OBD159_4321 GATAGATGGTCTCTGCCCCAGCA OBD159_4323 CACCGTGCTGCCAAGTTGACTCC
151 B OBD159_4325 CCAGACAGAGGGTGTAACCAGGC OBD159_4327 CCTCCTTCCCATTCTTGGCTTCC
152 B OBD159_4329 CGAGTATCTCACGCACACAAAGGGAC OBD159_4331 CCAGTCTCAGTGGAGGATTTTGAAGA
153 B OBD159_4333 AGCACCCTCAGAACTCTTTCCCC OBD159_4335 CACCTCCCCTGTCACCTGATGTC
表9.3h
編號 群組 探針 基因座 Probe_Count_Total
154 B ORF164_4_175570706_175582842_175638077_175645518_RR N/A N/A
155 B ORF183_6_47042220_47043847_47060758_47069708_FF N/A N/A
156 B ORF134_22_22364163_22372094_22390196_22400635_FF N/A N/A
157 B ORF18_X_130732955_130739067_130792590_130793708_FF N/A N/A
158 B ORF192_5_31151647_31161110_31225743_31233894_FF N/A N/A
159 B ORF171_2_209621630_209626755_209684451_209692640_FR N/A N/A
160 B ORF1_21_17365003_17366218_17434190_17435748_RR N/A N/A
161 B ORF17_2_209476172_209481006_209522065_209524486_RF N/A N/A
162 B ORF12_22_16921135_16923046_16991720_16993357_FR N/A N/A
163 B ORF15_2_66446190_66449017_66492459_66494190_FR N/A N/A
164 B ORF122_9_114576757_114578280_114619457_114622460_FR N/A N/A
165 B ORF153_15_99350884_99352277_99419798_99424615_FF N/A N/A
166 B ORF103_16_86444065_86445243_86506730_86509704_FF N/A N/A
167 B ORF13_20_19800689_19803183_19923213_19926075_FF N/A N/A
168 B ORF159_16_56062438_56065089_56102507_56114718_RF N/A N/A
169 B ORF161_5_93562856_93565579_93582366_93583770_RR N/A N/A
170 B ORF183_5_65124085_65127368_65185445_65188078_FR N/A N/A
171 B ORF186_4_175618295_175622237_175682057_175691642_FR N/A N/A
172 D ORF149_6_149229853_149231712_149287970_149291658_FR N/A N/A
173 D ORF192_10_12596194_12598368_12616738_12619998_RF N/A N/A
174 D ORF10_1_177039010_177043486_177103748_177111201_RF N/A N/A
175 D ORF168_12_30144610_30146709_30181629_30184999_RR N/A N/A
176 D ORF111_13_34426191_34433129_34463898_34472100_FR N/A N/A
177 D ORF12_3_46807202_46811416_46833087_46839270_RF N/A N/A
178 D ORF175_3_69167897_69172562_69218117_69221087_FR N/A N/A
179 D ORF19_20_46511970_46518882_46567001_46568090_RF N/A N/A
180 D ORF171_18_11015786_11021011_11118494_11119843_RR N/A N/A
181 D ORF10_6_154294994_154298490_154323035_154324807_FR N/A N/A
182 D ORF16_6_13526281_13531876_13559103_13561354_RR N/A N/A
表9.4a
編號 群組 Probe_Count_Sig HyperG_Stats FDR_HyperG Percent_Sig logFC AveExpr
154 B N/A N/A N/A N/A -0.518230715 -0.518230715
155 B N/A N/A N/A N/A -0.514627947 -0.514627947
156 B N/A N/A N/A N/A -0.513201545 -0.513201545
157 B N/A N/A N/A N/A -0.512145378 -0.512145378
158 B N/A N/A N/A N/A -0.511060289 -0.511060289
159 B N/A N/A N/A N/A -0.508206748 -0.508206748
160 B N/A N/A N/A N/A -0.507746284 -0.507746284
161 B N/A N/A N/A N/A -0.507097731 -0.507097731
162 B N/A N/A N/A N/A -0.506726527 -0.506726527
163 B N/A N/A N/A N/A -0.506585597 -0.506585597
164 B N/A N/A N/A N/A -0.50422625 -0.50422625
165 B N/A N/A N/A N/A -0.504110943 -0.504110943
166 B N/A N/A N/A N/A -0.503540575 -0.503540575
167 B N/A N/A N/A N/A -0.503236536 -0.503236536
168 B N/A N/A N/A N/A -0.502476785 -0.502476785
169 B N/A N/A N/A N/A -0.502379183 -0.502379183
170 B N/A N/A N/A N/A -0.502230544 -0.502230544
171 B N/A N/A N/A N/A -0.502183005 -0.502183005
172 D N/A N/A N/A N/A -0.966851209 -0.966851209
173 D N/A N/A N/A N/A -0.847700439 -0.847700439
174 D N/A N/A N/A N/A -0.762732385 -0.762732385
175 D N/A N/A N/A N/A -0.741191529 -0.741191529
176 D N/A N/A N/A N/A -0.700803469 -0.700803469
177 D N/A N/A N/A N/A -0.683750198 -0.683750198
178 D N/A N/A N/A N/A -0.658137917 -0.658137917
179 D N/A N/A N/A N/A -0.631933144 -0.631933144
180 D N/A N/A N/A N/A -0.629601593 -0.629601593
181 D N/A N/A N/A N/A -0.627203595 -0.627203595
182 D N/A N/A N/A N/A -0.624247879 -0.624247879
表9.4b
編號 群組 t P值 adj.P.Val B FC
154 B -5.362195428 0.000173338 0.002145992 0.77758692 0.698227597
155 B -8.49945946 0.00000209 0.00011818 5.307288691 0.699973424
156 B -9.314864265 0.000000799 0.0000646 6.280404769 0.700665835
157 B -5.055587241 0.000286539 0.003042515 0.261630837 0.701178965
158 B -5.496900549 0.000139574 0.001839195 1.000161135 0.701706539
159 B -9.322309266 0.000000792 0.0000641 6.28895319 0.703095834
160 B -6.545895416 0.0000282 0.000624419 2.645164027 0.703320277
161 B -4.126423931 0.001419892 0.009176186 -1.373842162 0.70363652
162 B -4.624780959 0.000593485 0.005070443 -0.484223374 0.703817589
163 B -11.97780294 0.0000000521 0.0000130 9.000200149 0.703886345
164 B -5.745709994 0.0000942 0.001400448 1.404538274 0.705038404
165 B -9.017723551 0.00000113 0.0000797 5.934356857 0.705094756
166 B -2.412457641 0.032864394 0.086824691 -4.493238931 0.70537357
167 B -6.832q978663 0.0000187 0.000475944 3.068166532 0.705522239
168 B -11.14627179 0.000000115 0.0000202 8.218374966 0.705893878
169 B -8.732794743 0.00000158 0.0000989 5.593394212 0.705941636
170 B -11.52540775 0.0000000798 0.0000163 8.581775324 0.706014371
171 B -7.81270396 0.00000495 0.000202535 4.427527157 0.706037636
172 D -13.63931618 0.0000000122 0.00000609 10.40829899 0.511621498
173 D -8.230893339 0.00000291 0.000144892 4.970072391 0.555669732
174 D -3.262995276 0.00683472 0.02833772 -2.957420767 0.589379022
175 D -5.848734747 0.0000802 0.001260075 1.569399495 0.598245055
176 D -7.105211691 0.0000127 0.000368733 3.458758895 0.615229476
177 D -7.565911003 0.00000684 0.00024651 4.097023669 0.622544902
178 D -5.942956947 0.0000694 0.001140129 1.718846375 0.633695679
179 D -6.513707717 0.0000295 0.000644318 2.597017253 0.645311149
180 D -4.978576007 0.000325767 0.003332827 0.13004571 0.646354884
181 D -6.084970954 0.0000558 0.000984165 1.941696022 0.647430127
182 D -4.384389265 0.000900527 0.00678304 -0.910115349 0.648757907
表9.4c
編號 群組 FC_1 LS 偵測到之環
154 B -1.432197759 -1 輕度自閉症
155 B -1.428625667 -1 輕度自閉症
156 B -1.427213874 -1 輕度自閉症
157 B -1.426169422 -1 輕度自閉症
158 B -1.425097167 -1 輕度自閉症
159 B -1.422281219 -1 輕度自閉症
160 B -1.421827342 -1 輕度自閉症
161 B -1.421188314 -1 輕度自閉症
162 B -1.42082269 -1 輕度自閉症
163 B -1.420683904 -1 輕度自閉症
164 B -1.418362452 -1 輕度自閉症
165 B -1.418249095 -1 輕度自閉症
166 B -1.417688502 -1 輕度自閉症
167 B -1.417389765 -1 輕度自閉症
168 B -1.416643537 -1 輕度自閉症
169 B -1.4165477 -1 輕度自閉症
170 B -1.416401763 -1 輕度自閉症
171 B -1.416355091 -1 輕度自閉症
172 D -1.95456994 -1 輕度自閉症
173 D -1.799630146 -1 輕度自閉症
174 D -1.696701042 -1 輕度自閉症
175 D -1.671555815 -1 輕度自閉症
176 D -1.625409768 -1 輕度自閉症
177 D -1.606309838 -1 輕度自閉症
178 D -1.578044531 -1 輕度自閉症
179 D -1.549640049 -1 輕度自閉症
180 D -1.547137685 -1 輕度自閉症
181 D -1.544568222 -1 輕度自閉症
182 D -1.541407033 -1 輕度自閉症
表9.4d
      探針序列 探針位置
編號 群組 60 mer Chr
154 B TTTTGCAAGTTGTTACTAGTACTGAATTTCGATTTACTTTGTCAGCATGTAGGACTTCCT 4
155 B GTGGAAAAAAGCTAATCTCATAATCTAGTCGATTTACAAAACACAATTTACCTTTTCCAA 6
156 B CCTTCCCTCGTATTCAGTGAGATTCATTTCGAAGCTCTGGAATGAATTTTCTTGGATCCT 22
157 B CCTTCTACAGGGAAGTGATGGAATTACTTCGAATAATTCACCCTTTACCAGGCCTGGGAG X
158 B AAAGAAAAGTCTGGATGACAATCTTTATTCGAAGCAAGTGAATGATAGTCAGGTAATATA 5
159 B CAATATTATATGTAGAGATTCTTTCATATCGACCATATGCTGTGATGCCACAACAAGCAA 2
160 B AACTGGTAATAAGTTATGCCTATGAATGTCGAATTCATGTTTTTTCTCTTGGAATTTTCT 21
161 B CTTTATGATAATTGCTATGTTAGTAGCCTCGAGACCATGATTGTGGATCCTAGTTTTGGA 2
162 B TACCTTTATTTTTGAAGCATATCTTCACTCGAGGTGTCTGAAGAAACACCAAAAATGCCT 22
163 B CAAAGTACTACTTTAATTTATGACATAATCGATAACTCTTTCACTTGGCTGCCCTCTCTA 2
164 B TATGCATATATGTATATATATGTAGCTATCGAAAGGCAAACAAAGACATCCTGAAGGATC 9
165 B TTATGGTTTTCTTCCAGAGTAGAAATCTTCGATTATTCTTTTCTTCCCTGCCACCTTGGG 15
166 B TATATACATATACATATGTATGTATATGTCGACTCCGGTCCTCGCGGCCGGCCGGCTAAG 16
167 B TTCATTCTCTTTTACCTGTCTATTTTCCTCGACAAATTGTAATGAGGTTTATCCACACTG 20
168 B GAGCCTTTACATATATTAGCTCATTTACTCGATGAAAGCATCCCATTGTCTTTTCCATAC 16
169 B AATTATGTGACCATTGTGCTTATTGTTCTCGAATTTGTGGCAATAGCTGCAAATTCCAGG 5
170 B ACTCCAAAATGGTCTCATTCTTACTGAATCGACCTGTGCTTATCCCAGAATTGTTTCCTG 5
171 B CTAAGCAGAGACTAAGAATATCTTAAAGTCGACAGTGAAGTCAAGGCTGACAAGGTCTCA 4
172 D AAAACACCTAAAATTAAGCAAAGTATTTTCGATCATAAAATTATGTTAAGCAAAGAATTA 6
173 D TTTTCACTCAACTTTCACTGGAGATTTATCGACAAAATAAATGTAGTAGAATTTCTTTGA 10
174 D ACTGAATTCTCACAACCATCCTGGTGTTTCGAATAAAAGAATCTGGATCTATTAAATGTC 1
175 D CTTCCAGTATTAAGGATATAGCTGAGAATCGAAGTCTCAGCTGAGGGATTACTTCTTCAG 12
176 D TACGTTAATTAAATAAATTTGTGCTCACTCGAAACAGGTTGGTTTTACACAAAGAGGTGT 13
177 D CTACAGTATATCATCTAAGATGTCTTCTTCGACTAACGTTTACTTGGCACTTGATGTTTT 3
178 D ATTGTGACAATCACATTTTAAGTACTCTTCGAAAGAGAATGATCTGAACATTTTAGGATG 3
179 D GCTTACTCAGAACTTAAAAATTTCATAATCGAATACTCTTCTCTGATGCTGAATTTTATA 20
180 D TTCGTGTTTATTGTTTTCCATAAGAAATTCGATTGCATCTAACCTTTGGATCTCATTCAA 18
181 D TTCATGAGTCATAGTCAATTATATAATCTCGATGTGACAAGTGCTTTTAAACAAGAGATT 6
182 D GGAACTATTACTTAAACTCTTAAACTCTTCGACATGATTAAGGTATTTCCCTTTTTCTCT 6
表9.4e
      探針位置 4 kb 序列位置
編號 群組 起點 1 終點 1 起點 2 終點 2 Chr 起點 1
154 B 175570708 175570737 175638079 175638108 4 175570708
155 B 47043816 47043845 47069677 47069706 6 47039846
156 B 22372063 22372092 22400604 22400633 22 22368093
157 B 130739036 130739065 130793677 130793706 X 130735066
158 B 31161079 31161108 31233863 31233892 5 31157109
159 B 209626724 209626753 209684453 209684482 2 209622754
160 B 17365005 17365034 17434192 17434221 21 17365005
161 B 209476174 209476203 209524455 209524484 2 209476174
162 B 16923015 16923044 16991722 16991751 22 16919045
163 B 66448986 66449015 66492461 66492490 2 66445016
164 B 114578249 114578278 114619459 114619488 9 114574279
165 B 99352246 99352275 99424584 99424613 15 99348276
166 B 86445212 86445241 86509673 86509702 16 86441242
167 B 19803152 19803181 19926044 19926073 20 19799182
168 B 56062440 56062469 56114687 56114716 16 56062440
169 B 93562858 93562887 93582368 93582397 5 93562858
170 B 65127337 65127366 65185447 65185476 5 65123367
171 B 175622206 175622235 175682059 175682088 4 175618236
172 D 149231681 149231710 149287972 149288001 6 149227711
173 D 12596196 12596225 12619967 12619996 10 12596196
174 D 177039012 177039041 177111170 177111199 1 177039012
175 D 30144612 30144641 30181631 30181660 12 30144612
176 D 34433098 34433127 34463900 34463929 13 34429128
177 D 46807204 46807233 46839239 46839268 3 46807204
178 D 69172531 69172560 69218119 69218148 3 69168561
179 D 46511972 46512001 46568059 46568088 20 46511972
180 D 11015788 11015817 11118496 11118525 18 11015788
181 D 154298459 154298488 154323037 154323066 6 154294489
182 D 13526283 13526312 13559105 13559134 6 13526283
表9.4f
      4 kb 序列位置   
編號 群組 終點 1 起點 2 終點 2 探針
154 B 175574707 175638079 175642078 ORF164_4_175570706_175582842_175638077_175645518_RR
155 B 47043845 47065707 47069706 ORF183_6_47042220_47043847_47060758_47069708_FF
156 B 22372092 22396634 22400633 ORF134_22_22364163_22372094_22390196_22400635_FF
157 B 130739065 130789707 130793706 ORF18_X_130732955_130739067_130792590_130793708_FF
158 B 31161108 31229893 31233892 ORF192_5_31151647_31161110_31225743_31233894_FF
159 B 209626753 209684453 209688452 ORF171_2_209621630_209626755_209684451_209692640_FR
160 B 17369004 17434192 17438191 ORF1_21_17365003_17366218_17434190_17435748_RR
161 B 209480173 209520485 209524484 ORF17_2_209476172_209481006_209522065_209524486_RF
162 B 16923044 16991722 16995721 ORF12_22_16921135_16923046_16991720_16993357_FR
163 B 66449015 66492461 66496460 ORF15_2_66446190_66449017_66492459_66494190_FR
164 B 114578278 114619459 114623458 ORF122_9_114576757_114578280_114619457_114622460_FR
165 B 99352275 99420614 99424613 ORF153_15_99350884_99352277_99419798_99424615_FF
166 B 86445241 86505703 86509702 ORF103_16_86444065_86445243_86506730_86509704_FF
167 B 19803181 19922074 19926073 ORF13_20_19800689_19803183_19923213_19926075_FF
168 B 56066439 56110717 56114716 ORF159_16_56062438_56065089_56102507_56114718_RF
169 B 93566857 93582368 93586367 ORF161_5_93562856_93565579_93582366_93583770_RR
170 B 65127366 65185447 65189446 ORF183_5_65124085_65127368_65185445_65188078_FR
171 B 175622235 175682059 175686058 ORF186_4_175618295_175622237_175682057_175691642_FR
172 D 149231710 149287972 149291971 ORF149_6_149229853_149231712_149287970_149291658_FR
173 D 12600195 12615997 12619996 ORF192_10_12596194_12598368_12616738_12619998_RF
174 D 177043011 177107200 177111199 ORF10_1_177039010_177043486_177103748_177111201_RF
175 D 30148611 30181631 30185630 ORF168_12_30144610_30146709_30181629_30184999_RR
176 D 34433127 34463900 34467899 ORF111_13_34426191_34433129_34463898_34472100_FR
177 D 46811203 46835269 46839268 ORF12_3_46807202_46811416_46833087_46839270_RF
178 D 69172560 69218119 69222118 ORF175_3_69167897_69172562_69218117_69221087_FR
179 D 46515971 46564089 46568088 ORF19_20_46511970_46518882_46567001_46568090_RF
180 D 11019787 11118496 11122495 ORF171_18_11015786_11021011_11118494_11119843_RR
181 D 154298488 154323037 154327036 ORF10_6_154294994_154298490_154323035_154324807_FR
182 D 13530282 13559105 13563104 ORF16_6_13526281_13531876_13559103_13561354_RR
表9.4g
編號 群組 PCR- 引子 1_ID PCR_ 引子 1 PCR- 引子 2_ID PCR_ 引子 2
154 B OBD159_4337 GCCTAAAACTTCAGCCTAAAGGATGA OBD159_4339 TACCAGGAATAATAAAGCAGGGACTT
155 B OBD159_4341 ACCCACTTGTCTTCCACACCAGC OBD159_4343 GGGTTGCTGGCTGGAGTCTTCTG
156 B OBD159_4345 TGGGACTCAGGACTCATTGCTGCC OBD159_4347 CTGTCTCTACCCAATAATGTCAGGTC
157 B OBD159_4349 GCCAAGTCTAACACCTGCTTTGAAGA OBD159_4351 GAATGCTCTGTTCCATCTGGGTGCTG
158 B OBD159_4353 CACCTTCAGGCTGGCATCTCCCT OBD159_4355 CGCCTCACTCTCTACTACTCAGC
159 B OBD159_4357 CCATTCTTCCAGAGATGTCAAAACCC OBD159_4359 CACTGGGCTAATGTAAGGTTTGCCAT
160 B OBD159_4361 CTAATACAGTCTTCTACCCAAAATGG OBD159_4363 GGCAGAGAAAGTTTTGTCCTCAGTTC
161 B OBD159_4365 CACACATAATCCAGAGTCAGGGAGAG OBD159_4367 GACTGCTATCACTTTGAGATGGACAG
162 B OBD159_4369 CCATCTGCTGTCATTTCCTGTGATTC OBD159_4371 AAGCACAGGTATGGGAGCACACACAG
163 B OBD159_4373 CCACTGTCAGGGAAATAGTTGAAGGA OBD159_4375 GAAACCAGCCAGATGAGAGCAACAGC
164 B OBD159_4377 AACCCCTGATTCCTTTCTTCCCTACT OBD159_4379 TGGAGACTCAGAACCATTCCCAGGTC
165 B OBD159_4381 GCCAGGGTGATTAGACCAAGGAG OBD159_4383 TGGCATAGCCGACCTGTGCTTGC
166 B OBD159_4385 AAGAGAGACGCCCAGAAGCCAGAAA OBD159_4387 AGAGTGGGTAGGCGGTCCCTCGC
167 B OBD159_4389 GCACTGCCATCTGTGGGCTGAGA OBD159_4391 GGGAACACACACACAGGTGACCA
168 B OBD159_4393 GATAGGGTTTTGCCACCTTGGATAAG OBD159_4395 GCCAATACCATTTCCTTGACCAGGGC
169 B OBD159_4397 GTCCTGTTTTGAATGCCCAGTTCTTT OBD159_4399 GAGCGTGAAGAGAGTGTCATTGAAAA
170 B OBD159_4401 CTATCGGCGGGCTTTAGCAGTGC OBD159_4403 GGGACCACTGCCTCAGATAAAGC
171 B OBD159_4405 CCTGGATGGAAACAGACACAACACAA OBD159_4407 GTGTGACCTTTGCTCCAGTGCCCTAT
172 D OBD159_1013 ATTGACTGTCTTGGGAAAAGCACTTA OBD159_1015 GGGACTGAGTGACACAAGGACCATTT
173 D OBD159_1321 GTAGCAAACCCACTTCCCTCCTGC OBD159_1323 CTCTTCTGTTTGTGAGGGCTGCC
174 D OBD159_717 GCCCCTCTTCTTTGCCAAGCACT OBD159_719 GCCAAGGGTTCAGAAAGCCCAGG
175 D OBD159_1157 CATTCTTCCCTCAGCCATCCATTTGG OBD159_1159 GCCTTTTATTCTGTGTGTGGCTAAGC
176 D OBD159_797 CACAGTGGGCTCAGTGTCAACAAACC OBD159_799 CTCTCTTGGTGTTTGGAAATCTGTGC
177 D OBD159_833 CCAGCAAAAGGCAGGAATCAGTGC OBD159_835 GGAAAGTCCCAGGCTCCAGGAAG
178 D OBD159_1225 GTGTCTCGGAGTCTCTTTGAACCAGC OBD159_1227 CCGACTTACGGTGTCCATTATTATGC
179 D OBD159_1293 CTACCATAGCCCTTTTATCAATCCAG OBD159_1295 CCATTCGCCATTCTTCCTTACCCAGC
180 D OBD159_1201 GAGAATGTCACCAGGATTGCCCAAGC OBD159_1203 CATTCCAGCATTGGTTGGCATTTGAA
181 D OBD159_733 TCCCAAGTGGTCCCCAAAATGTCTTT OBD159_735 GGGCAGGGTATCTAAGGCAATGGTTC
182 D OBD159_1121 GTGCCTCAGTTTTCCTCATCCCTAAG OBD159_1123 GGGAATGTATGCTGTTCTCAGAG
表9.4h
   探針 基因
1 7_106136911_106139119_106155635_106157326_RR CDHR3, NAMPT, SYPL1
2 2_209634852_209638927_209684451_209692640_FF RPE, MAP2, UNC80
3 2_39607186_39609982_39623225_39627003_FR MAP4K3, TMEM178A, THUMPD2
4 6_46267215_46269920_46286216_46295988_RF ENPP4, RCAN2, ENPP5
5 3_120801777_120809148_120844722_120858831_FR RABL3, STXBP5L, GTF2E1
6 10_3161199_3165742_3210550_3216745_RR KLF6, PITRM1, PFKP
7 2_198099686_198102962_198137324_198146976_RR MARS2, BOLL, PLCL1
8 12_30144610_30146709_30181629_30184999_RR CAPRIN2, IPO8, TMTC1
9 19_52224152_52228867_52265664_52267714_RF ZNF480, ZNF766, PPP2R1A
10 6_157189218_157193153_157237058_157240060_RF ZDHHC14, ARID1B, TMEM242
11 7_106136911_106139119_106183992_106185753_RR CDHR3, SYPL1, NAMPT
12 21_17083642_17087491_17108209_17114129_FF C21orf91, CXADR, BTG3
13 10_106496977_106502145_106531472_106538179_RF CFAP58, SORCS1, SORCS3
14 8_31175232_31178937_31205589_31213041_FR TEX15, WRN, PURG
15 13_34426191_34433129_34463898_34472100_FR MAB21L1, RFC3, NBEA
16 5_149610432_149612632_149663575_149665859_RR PPARGC1B, ARHGEF37, CSNK1A1
17 3_43042539_43050797_43066697_43075829_RF POMGNT2, FAM198A, RP11-136C24.3
18 14_99794535_99796770_99815362_99818414_RF HHIPL1, EML1, CYP46A1
19 7_22368712_22370568_22401546_22402661_RR IL6, RAPGEF5, STEAP1B
20 18_58202022_58205094_58215328_58217936_RF ATP8B1, ALPK2, NEDD4L
表10.a
   標記 SHAP 分類
1 OBD159.517.519 0.57490882 健康對照
2 OBD159.401.403 0.42173229 輕度
3 OBD159.089.091 0.3262595 重度
4 OBD159.853.855 0.31379081 重度
5 OBD159.741.743 0.30062315 輕度
6 OBD159.657.659 0.23915455 健康對照
7 OBD159.409.411 0.22696029 重度
8 OBD159.065.067 0.20842332 健康對照
9 OBD159.389.391 0.19269562 健康對照
10 OBD159.781.783 0.19201188 健康對照
11 OBD159.505.507 0.17399292 輕度
12 OBD159.669.671 0.15368236 重度
13 OBD159.773.775 0.15091799 健康對照
14 OBD159.673.675 0.14476814 重度
15 OBD159.073.075 0.1442338 健康對照
16 OBD159.697.699 0.1397228 輕度
17 OBD159.701.703 0.12426417 輕度
18 OBD159.833.835 0.11698199 輕度
19 OBD159.537.539 0.09678731 輕度
20 OBD159.049.051 0.08189849 輕度
表10.b
圖1展示存在於輕度或重度ASD (相對於健康對照(HC)進行鑑別)中的前200種統計學上顯著之標記。 圖2展示針對已確定的顯著標記，在重疊(上游、下游，在域內部重疊)之多個組合情境中鑑別出最近編碼區(基因)作為染色質長程域。 圖3展示繪製在VENN圖示上的各群組之顯著富集之TF之數目。 圖4展示特有輕度ASD標記之TF富集路徑。 圖5展示輕度與重度ASD中之TF標記之間的關係。 圖6展示一系列經鑑別輕度ASD標記路徑以用於進一步分析。圖7展示針對重度ASD之相同標記路徑。 圖7為圖3之重複，作為在對重度ASD標記進行String網絡及富集分析之前的提醒。 圖8展示基於輕度路徑標記之主分量分析。 圖9展示使用重度ASD路徑標記之相同分析。 圖10展示偵測染色體相互作用之較佳方法。 圖11展示輕度ASD所特有之標記的網絡及路徑。 圖12展示在所有輕度ASD標記上形成的網絡之富集。 圖13展示常見ASD標記之路徑富集。 圖14展示在所有常見ASD標記上形成的網絡之富集。 圖15展示重度ASD所特有之標記的網絡路徑。 圖16展示由重度ASD所特有之標記形成的網絡之富集。 圖17展示針對所有重度ASD標記形成的網絡之富集。 圖18展示使用重度ASD標記建構的TF網絡。 圖19展示表10之標記的效能特徵。訓練資料在左側且測試在右側。
Figure 12_A0101_SEQ_0001
Figure 12_A0101_SEQ_0002
Figure 12_A0101_SEQ_0003
Figure 12_A0101_SEQ_0004
Figure 12_A0101_SEQ_0005
Figure 12_A0101_SEQ_0006
Figure 12_A0101_SEQ_0007
Figure 12_A0101_SEQ_0008
Figure 12_A0101_SEQ_0009
Figure 12_A0101_SEQ_0010
Figure 12_A0101_SEQ_0011
Figure 12_A0101_SEQ_0012
Figure 12_A0101_SEQ_0013
Figure 12_A0101_SEQ_0014
Figure 12_A0101_SEQ_0015
Figure 12_A0101_SEQ_0016
Figure 12_A0101_SEQ_0017
Figure 12_A0101_SEQ_0018
Figure 12_A0101_SEQ_0019
Figure 12_A0101_SEQ_0020
Figure 12_A0101_SEQ_0021
Figure 12_A0101_SEQ_0022
Figure 12_A0101_SEQ_0023
Figure 12_A0101_SEQ_0024
Figure 12_A0101_SEQ_0025
Figure 12_A0101_SEQ_0026
Figure 12_A0101_SEQ_0027
Figure 12_A0101_SEQ_0028
Figure 12_A0101_SEQ_0029
Figure 12_A0101_SEQ_0030
Figure 12_A0101_SEQ_0031
Figure 12_A0101_SEQ_0032
Figure 12_A0101_SEQ_0033
Figure 12_A0101_SEQ_0034
Figure 12_A0101_SEQ_0035
Figure 12_A0101_SEQ_0036
Figure 12_A0101_SEQ_0037
Figure 12_A0101_SEQ_0038
Figure 12_A0101_SEQ_0039
Figure 12_A0101_SEQ_0040
Figure 12_A0101_SEQ_0041
Figure 12_A0101_SEQ_0042
Figure 12_A0101_SEQ_0043
Figure 12_A0101_SEQ_0044
Figure 12_A0101_SEQ_0045
Figure 12_A0101_SEQ_0046
Figure 12_A0101_SEQ_0047
Figure 12_A0101_SEQ_0048
Figure 12_A0101_SEQ_0049
Figure 12_A0101_SEQ_0050
Figure 12_A0101_SEQ_0051
Figure 12_A0101_SEQ_0052
Figure 12_A0101_SEQ_0053
Figure 12_A0101_SEQ_0054
Figure 12_A0101_SEQ_0055
Figure 12_A0101_SEQ_0056
Figure 12_A0101_SEQ_0057
Figure 12_A0101_SEQ_0058
Figure 12_A0101_SEQ_0059
Figure 12_A0101_SEQ_0060
Figure 12_A0101_SEQ_0061
Figure 12_A0101_SEQ_0062
Figure 12_A0101_SEQ_0063
Figure 12_A0101_SEQ_0064
Figure 12_A0101_SEQ_0065
Figure 12_A0101_SEQ_0066
Figure 12_A0101_SEQ_0067
Figure 12_A0101_SEQ_0068
Figure 12_A0101_SEQ_0069
Figure 12_A0101_SEQ_0070
Figure 12_A0101_SEQ_0071
Figure 12_A0101_SEQ_0072
Figure 12_A0101_SEQ_0073
Figure 12_A0101_SEQ_0074
Figure 12_A0101_SEQ_0075
Figure 12_A0101_SEQ_0076
Figure 12_A0101_SEQ_0077
Figure 12_A0101_SEQ_0078
Figure 12_A0101_SEQ_0079
Figure 12_A0101_SEQ_0080
Figure 12_A0101_SEQ_0081
Figure 12_A0101_SEQ_0082
Figure 12_A0101_SEQ_0083
Figure 12_A0101_SEQ_0084
Figure 12_A0101_SEQ_0085
Figure 12_A0101_SEQ_0086
Figure 12_A0101_SEQ_0087
Figure 12_A0101_SEQ_0088
Figure 12_A0101_SEQ_0089
Figure 12_A0101_SEQ_0090
Figure 12_A0101_SEQ_0091
Figure 12_A0101_SEQ_0092
Figure 12_A0101_SEQ_0093
Figure 12_A0101_SEQ_0094
Figure 12_A0101_SEQ_0095
Figure 12_A0101_SEQ_0096
Figure 12_A0101_SEQ_0097
Figure 12_A0101_SEQ_0098
Figure 12_A0101_SEQ_0099
Figure 12_A0101_SEQ_0100
Figure 12_A0101_SEQ_0101
Figure 12_A0101_SEQ_0102
Figure 12_A0101_SEQ_0103
Figure 12_A0101_SEQ_0104
Figure 12_A0101_SEQ_0105
Figure 12_A0101_SEQ_0106
Figure 12_A0101_SEQ_0107
Figure 12_A0101_SEQ_0108
Figure 12_A0101_SEQ_0109
Figure 12_A0101_SEQ_0110
Figure 12_A0101_SEQ_0111
Figure 12_A0101_SEQ_0112
Figure 12_A0101_SEQ_0113
Figure 12_A0101_SEQ_0114
Figure 12_A0101_SEQ_0115
Figure 12_A0101_SEQ_0116
Figure 12_A0101_SEQ_0117
Figure 12_A0101_SEQ_0118
Figure 12_A0101_SEQ_0119
Figure 12_A0101_SEQ_0120
Figure 12_A0101_SEQ_0121
Figure 12_A0101_SEQ_0122
Figure 12_A0101_SEQ_0123
Figure 12_A0101_SEQ_0124
Figure 12_A0101_SEQ_0125
Figure 12_A0101_SEQ_0126
Figure 12_A0101_SEQ_0127
Figure 12_A0101_SEQ_0128
Figure 12_A0101_SEQ_0129
Figure 12_A0101_SEQ_0130
Figure 12_A0101_SEQ_0131
Figure 12_A0101_SEQ_0132
Figure 12_A0101_SEQ_0133
Figure 12_A0101_SEQ_0134
Figure 12_A0101_SEQ_0135
Figure 12_A0101_SEQ_0136
Figure 12_A0101_SEQ_0137
Figure 12_A0101_SEQ_0138
Figure 12_A0101_SEQ_0139
Figure 12_A0101_SEQ_0140
Figure 12_A0101_SEQ_0141
Figure 12_A0101_SEQ_0142
Figure 12_A0101_SEQ_0143
Figure 12_A0101_SEQ_0144
Figure 12_A0101_SEQ_0145
Figure 12_A0101_SEQ_0146
Figure 12_A0101_SEQ_0147
Figure 12_A0101_SEQ_0148
Figure 12_A0101_SEQ_0149
Figure 12_A0101_SEQ_0150
Figure 12_A0101_SEQ_0151
Figure 12_A0101_SEQ_0152
Figure 12_A0101_SEQ_0153
Figure 12_A0101_SEQ_0154
Figure 12_A0101_SEQ_0155
Figure 12_A0101_SEQ_0156
Figure 12_A0101_SEQ_0157
Figure 12_A0101_SEQ_0158
Figure 12_A0101_SEQ_0159
Figure 12_A0101_SEQ_0160
Figure 12_A0101_SEQ_0161
Figure 12_A0101_SEQ_0162
Figure 12_A0101_SEQ_0163
Figure 12_A0101_SEQ_0164
Figure 12_A0101_SEQ_0165
Figure 12_A0101_SEQ_0166
Figure 12_A0101_SEQ_0167
Figure 12_A0101_SEQ_0168
Figure 12_A0101_SEQ_0169
Figure 12_A0101_SEQ_0170
Figure 12_A0101_SEQ_0171
Figure 12_A0101_SEQ_0172
Figure 12_A0101_SEQ_0173
Figure 12_A0101_SEQ_0174
Figure 12_A0101_SEQ_0175
Figure 12_A0101_SEQ_0176
Figure 12_A0101_SEQ_0177
Figure 12_A0101_SEQ_0178
Figure 12_A0101_SEQ_0179
Figure 12_A0101_SEQ_0180
Figure 12_A0101_SEQ_0181
Figure 12_A0101_SEQ_0182
Figure 12_A0101_SEQ_0183
Figure 12_A0101_SEQ_0184
Figure 12_A0101_SEQ_0185
Figure 12_A0101_SEQ_0186
Figure 12_A0101_SEQ_0187
Figure 12_A0101_SEQ_0188
Figure 12_A0101_SEQ_0189
Figure 12_A0101_SEQ_0190
Figure 12_A0101_SEQ_0191
Figure 12_A0101_SEQ_0192
Figure 12_A0101_SEQ_0193
Figure 12_A0101_SEQ_0194
Figure 12_A0101_SEQ_0195
Figure 12_A0101_SEQ_0196
Figure 12_A0101_SEQ_0197
Figure 12_A0101_SEQ_0198
Figure 12_A0101_SEQ_0199
Figure 12_A0101_SEQ_0200
Figure 12_A0101_SEQ_0201
Figure 12_A0101_SEQ_0202
Figure 12_A0101_SEQ_0203
Figure 12_A0101_SEQ_0204
Figure 12_A0101_SEQ_0205
Figure 12_A0101_SEQ_0206
Figure 12_A0101_SEQ_0207
Figure 12_A0101_SEQ_0208
Figure 12_A0101_SEQ_0209
Figure 12_A0101_SEQ_0210
Figure 12_A0101_SEQ_0211
Figure 12_A0101_SEQ_0212
Figure 12_A0101_SEQ_0213
Figure 12_A0101_SEQ_0214
Figure 12_A0101_SEQ_0215
Figure 12_A0101_SEQ_0216
Figure 12_A0101_SEQ_0217
Figure 12_A0101_SEQ_0218
Figure 12_A0101_SEQ_0219
Figure 12_A0101_SEQ_0220
Figure 12_A0101_SEQ_0221
Figure 12_A0101_SEQ_0222
Figure 12_A0101_SEQ_0223
Figure 12_A0101_SEQ_0224
Figure 12_A0101_SEQ_0225
Figure 12_A0101_SEQ_0226
Figure 12_A0101_SEQ_0227
Figure 12_A0101_SEQ_0228
Figure 12_A0101_SEQ_0229
Figure 12_A0101_SEQ_0230
Figure 12_A0101_SEQ_0231
Figure 12_A0101_SEQ_0232
Figure 12_A0101_SEQ_0233
Figure 12_A0101_SEQ_0234
Figure 12_A0101_SEQ_0235
Figure 12_A0101_SEQ_0236
Figure 12_A0101_SEQ_0237
Figure 12_A0101_SEQ_0238
Figure 12_A0101_SEQ_0239
Figure 12_A0101_SEQ_0240
Figure 12_A0101_SEQ_0241
Figure 12_A0101_SEQ_0242
Figure 12_A0101_SEQ_0243
Figure 12_A0101_SEQ_0244
Figure 12_A0101_SEQ_0245
Figure 12_A0101_SEQ_0246
Figure 12_A0101_SEQ_0247
Figure 12_A0101_SEQ_0248
Figure 12_A0101_SEQ_0249
Figure 12_A0101_SEQ_0250
Figure 12_A0101_SEQ_0251
Figure 12_A0101_SEQ_0252
Figure 12_A0101_SEQ_0253
Figure 12_A0101_SEQ_0254
Figure 12_A0101_SEQ_0255
Figure 12_A0101_SEQ_0256
Figure 12_A0101_SEQ_0257
Figure 12_A0101_SEQ_0258
Figure 12_A0101_SEQ_0259
Figure 12_A0101_SEQ_0260
Figure 12_A0101_SEQ_0261
Figure 12_A0101_SEQ_0262
Figure 12_A0101_SEQ_0263
Figure 12_A0101_SEQ_0264
Figure 12_A0101_SEQ_0265
Figure 12_A0101_SEQ_0266
Figure 12_A0101_SEQ_0267
Figure 12_A0101_SEQ_0268
Figure 12_A0101_SEQ_0269
Figure 12_A0101_SEQ_0270
Figure 12_A0101_SEQ_0271
Figure 12_A0101_SEQ_0272
Figure 12_A0101_SEQ_0273
Figure 12_A0101_SEQ_0274
Figure 12_A0101_SEQ_0275
Figure 12_A0101_SEQ_0276
Figure 12_A0101_SEQ_0277
Figure 12_A0101_SEQ_0278
Figure 12_A0101_SEQ_0279
Figure 12_A0101_SEQ_0280
Figure 12_A0101_SEQ_0281
Figure 12_A0101_SEQ_0282
Figure 12_A0101_SEQ_0283
Figure 12_A0101_SEQ_0284
Figure 12_A0101_SEQ_0285
Figure 12_A0101_SEQ_0286
Figure 12_A0101_SEQ_0287
Figure 12_A0101_SEQ_0288
Figure 12_A0101_SEQ_0289
Figure 12_A0101_SEQ_0290
Figure 12_A0101_SEQ_0291
Figure 12_A0101_SEQ_0292
Figure 12_A0101_SEQ_0293
Figure 12_A0101_SEQ_0294
Figure 12_A0101_SEQ_0295
Figure 12_A0101_SEQ_0296
Figure 12_A0101_SEQ_0297
Figure 12_A0101_SEQ_0298
Figure 12_A0101_SEQ_0299
Figure 12_A0101_SEQ_0300
Figure 12_A0101_SEQ_0301
Figure 12_A0101_SEQ_0302
Figure 12_A0101_SEQ_0303
Figure 12_A0101_SEQ_0304
Figure 12_A0101_SEQ_0305
Figure 12_A0101_SEQ_0306
Figure 12_A0101_SEQ_0307
Figure 12_A0101_SEQ_0308
Figure 12_A0101_SEQ_0309
Figure 12_A0101_SEQ_0310
Figure 12_A0101_SEQ_0311
Figure 12_A0101_SEQ_0312
Figure 12_A0101_SEQ_0313
Figure 12_A0101_SEQ_0314
Figure 12_A0101_SEQ_0315
Figure 12_A0101_SEQ_0316
Figure 12_A0101_SEQ_0317
Figure 12_A0101_SEQ_0318
Figure 12_A0101_SEQ_0319
Figure 12_A0101_SEQ_0320
Figure 12_A0101_SEQ_0321
Figure 12_A0101_SEQ_0322
Figure 12_A0101_SEQ_0323
Figure 12_A0101_SEQ_0324
Figure 12_A0101_SEQ_0325
Figure 12_A0101_SEQ_0326
Figure 12_A0101_SEQ_0327
Figure 12_A0101_SEQ_0328
Figure 12_A0101_SEQ_0329
Figure 12_A0101_SEQ_0330
Figure 12_A0101_SEQ_0331
Figure 12_A0101_SEQ_0332
Figure 12_A0101_SEQ_0333
Figure 12_A0101_SEQ_0334
Figure 12_A0101_SEQ_0335
Figure 12_A0101_SEQ_0336
Figure 12_A0101_SEQ_0337
Figure 12_A0101_SEQ_0338
Figure 12_A0101_SEQ_0339
Figure 12_A0101_SEQ_0340
Figure 12_A0101_SEQ_0341
Figure 12_A0101_SEQ_0342
Figure 12_A0101_SEQ_0343
Figure 12_A0101_SEQ_0344
Figure 12_A0101_SEQ_0345
Figure 12_A0101_SEQ_0346
Figure 12_A0101_SEQ_0347
Figure 12_A0101_SEQ_0348
Figure 12_A0101_SEQ_0349
Figure 12_A0101_SEQ_0350
Figure 12_A0101_SEQ_0351
Figure 12_A0101_SEQ_0352
Figure 12_A0101_SEQ_0353
Figure 12_A0101_SEQ_0354
Figure 12_A0101_SEQ_0355
Figure 12_A0101_SEQ_0356
Figure 12_A0101_SEQ_0357
Figure 12_A0101_SEQ_0358
Figure 12_A0101_SEQ_0359
Figure 12_A0101_SEQ_0360
Figure 12_A0101_SEQ_0361
Figure 12_A0101_SEQ_0362
Figure 12_A0101_SEQ_0363
Figure 12_A0101_SEQ_0364
Figure 12_A0101_SEQ_0365
Figure 12_A0101_SEQ_0366
Figure 12_A0101_SEQ_0367
Figure 12_A0101_SEQ_0368
Figure 12_A0101_SEQ_0369
Figure 12_A0101_SEQ_0370
Figure 12_A0101_SEQ_0371
Figure 12_A0101_SEQ_0372
Figure 12_A0101_SEQ_0373
Figure 12_A0101_SEQ_0374
Figure 12_A0101_SEQ_0375
Figure 12_A0101_SEQ_0376
Figure 12_A0101_SEQ_0377
Figure 12_A0101_SEQ_0378
Figure 12_A0101_SEQ_0379
Figure 12_A0101_SEQ_0380
Figure 12_A0101_SEQ_0381
Figure 12_A0101_SEQ_0382
Figure 12_A0101_SEQ_0383
Figure 12_A0101_SEQ_0384
Figure 12_A0101_SEQ_0385
Figure 12_A0101_SEQ_0386
Figure 12_A0101_SEQ_0387
Figure 12_A0101_SEQ_0388
Figure 12_A0101_SEQ_0389
Figure 12_A0101_SEQ_0390
Figure 12_A0101_SEQ_0391
Figure 12_A0101_SEQ_0392
Figure 12_A0101_SEQ_0393
Figure 12_A0101_SEQ_0394
Figure 12_A0101_SEQ_0395
Figure 12_A0101_SEQ_0396
Figure 12_A0101_SEQ_0397
Figure 12_A0101_SEQ_0398
Figure 12_A0101_SEQ_0399
Figure 12_A0101_SEQ_0400
Figure 12_A0101_SEQ_0401
Figure 12_A0101_SEQ_0402
Figure 12_A0101_SEQ_0403
Figure 12_A0101_SEQ_0404
Figure 12_A0101_SEQ_0405
Figure 12_A0101_SEQ_0406
Figure 12_A0101_SEQ_0407
Figure 12_A0101_SEQ_0408
Figure 12_A0101_SEQ_0409
Figure 12_A0101_SEQ_0410
Figure 12_A0101_SEQ_0411
Figure 12_A0101_SEQ_0412
Figure 12_A0101_SEQ_0413
Figure 12_A0101_SEQ_0414
Figure 12_A0101_SEQ_0415
Figure 12_A0101_SEQ_0416
Figure 12_A0101_SEQ_0417
Figure 12_A0101_SEQ_0418
Figure 12_A0101_SEQ_0419
Figure 12_A0101_SEQ_0420
Figure 12_A0101_SEQ_0421
Figure 12_A0101_SEQ_0422
Figure 12_A0101_SEQ_0423
Figure 12_A0101_SEQ_0424
Figure 12_A0101_SEQ_0425
Figure 12_A0101_SEQ_0426
Figure 12_A0101_SEQ_0427
Figure 12_A0101_SEQ_0428
Figure 12_A0101_SEQ_0429
Figure 12_A0101_SEQ_0430
Figure 12_A0101_SEQ_0431
Figure 12_A0101_SEQ_0432
Figure 12_A0101_SEQ_0433
Figure 12_A0101_SEQ_0434
Figure 12_A0101_SEQ_0435
Figure 12_A0101_SEQ_0436
Figure 12_A0101_SEQ_0437
Figure 12_A0101_SEQ_0438
Figure 12_A0101_SEQ_0439
Figure 12_A0101_SEQ_0440
Figure 12_A0101_SEQ_0441
Figure 12_A0101_SEQ_0442
Figure 12_A0101_SEQ_0443
Figure 12_A0101_SEQ_0444
Figure 12_A0101_SEQ_0445
Figure 12_A0101_SEQ_0446
Figure 12_A0101_SEQ_0447
Figure 12_A0101_SEQ_0448
Figure 12_A0101_SEQ_0449
Figure 12_A0101_SEQ_0450
Figure 12_A0101_SEQ_0451
Figure 12_A0101_SEQ_0452
Figure 12_A0101_SEQ_0453
Figure 12_A0101_SEQ_0454
Figure 12_A0101_SEQ_0455
Figure 12_A0101_SEQ_0456
Figure 12_A0101_SEQ_0457
Figure 12_A0101_SEQ_0458
Figure 12_A0101_SEQ_0459
Figure 12_A0101_SEQ_0460
Figure 12_A0101_SEQ_0461
Figure 12_A0101_SEQ_0462
Figure 12_A0101_SEQ_0463
Figure 12_A0101_SEQ_0464
Figure 12_A0101_SEQ_0465
Figure 12_A0101_SEQ_0466
Figure 12_A0101_SEQ_0467
Figure 12_A0101_SEQ_0468
Figure 12_A0101_SEQ_0469
Figure 12_A0101_SEQ_0470
Figure 12_A0101_SEQ_0471
Figure 12_A0101_SEQ_0472
Figure 12_A0101_SEQ_0473
Figure 12_A0101_SEQ_0474
Figure 12_A0101_SEQ_0475
Figure 12_A0101_SEQ_0476
Figure 12_A0101_SEQ_0477
Figure 12_A0101_SEQ_0478
Figure 12_A0101_SEQ_0479
Figure 12_A0101_SEQ_0480
Figure 12_A0101_SEQ_0481
Figure 12_A0101_SEQ_0482
Figure 12_A0101_SEQ_0483
Figure 12_A0101_SEQ_0484
Figure 12_A0101_SEQ_0485
Figure 12_A0101_SEQ_0486
Figure 12_A0101_SEQ_0487
Figure 12_A0101_SEQ_0488
Figure 12_A0101_SEQ_0489
Figure 12_A0101_SEQ_0490
Figure 12_A0101_SEQ_0491
Figure 12_A0101_SEQ_0492
Figure 12_A0101_SEQ_0493
Figure 12_A0101_SEQ_0494
Figure 12_A0101_SEQ_0495
Figure 12_A0101_SEQ_0496
Figure 12_A0101_SEQ_0497
Figure 12_A0101_SEQ_0498
Figure 12_A0101_SEQ_0499
Figure 12_A0101_SEQ_0500
Figure 12_A0101_SEQ_0501
Figure 12_A0101_SEQ_0502
Figure 12_A0101_SEQ_0503
Figure 12_A0101_SEQ_0504
Figure 12_A0101_SEQ_0505
Figure 12_A0101_SEQ_0506
Figure 12_A0101_SEQ_0507
Figure 12_A0101_SEQ_0508
Figure 12_A0101_SEQ_0509
Figure 12_A0101_SEQ_0510
Figure 12_A0101_SEQ_0511
Figure 12_A0101_SEQ_0512
Figure 12_A0101_SEQ_0513
Figure 12_A0101_SEQ_0514
Figure 12_A0101_SEQ_0515
Figure 12_A0101_SEQ_0516
Figure 12_A0101_SEQ_0517
Figure 12_A0101_SEQ_0518
Figure 12_A0101_SEQ_0519
Figure 12_A0101_SEQ_0520
Figure 12_A0101_SEQ_0521
Figure 12_A0101_SEQ_0522
Figure 12_A0101_SEQ_0523
Figure 12_A0101_SEQ_0524
Figure 12_A0101_SEQ_0525
Figure 12_A0101_SEQ_0526
Figure 12_A0101_SEQ_0527
Figure 12_A0101_SEQ_0528
Figure 12_A0101_SEQ_0529
Figure 12_A0101_SEQ_0530
Figure 12_A0101_SEQ_0531
Figure 12_A0101_SEQ_0532
Figure 12_A0101_SEQ_0533
Figure 12_A0101_SEQ_0534
Figure 12_A0101_SEQ_0535
Figure 12_A0101_SEQ_0536
Figure 12_A0101_SEQ_0537
Figure 12_A0101_SEQ_0538
Figure 12_A0101_SEQ_0539
Figure 12_A0101_SEQ_0540
Figure 12_A0101_SEQ_0541
Figure 12_A0101_SEQ_0542
Figure 12_A0101_SEQ_0543
Figure 12_A0101_SEQ_0544
Figure 12_A0101_SEQ_0545
Figure 12_A0101_SEQ_0546
Figure 12_A0101_SEQ_0547
Figure 12_A0101_SEQ_0548
Figure 12_A0101_SEQ_0549
Figure 12_A0101_SEQ_0550
Figure 12_A0101_SEQ_0551
Figure 12_A0101_SEQ_0552
Figure 12_A0101_SEQ_0553
Figure 12_A0101_SEQ_0554
Figure 12_A0101_SEQ_0555
Figure 12_A0101_SEQ_0556
Figure 12_A0101_SEQ_0557
Figure 12_A0101_SEQ_0558
Figure 12_A0101_SEQ_0559
Figure 12_A0101_SEQ_0560
Figure 12_A0101_SEQ_0561
Figure 12_A0101_SEQ_0562
Figure 12_A0101_SEQ_0563
Figure 12_A0101_SEQ_0564
Figure 12_A0101_SEQ_0565
Figure 12_A0101_SEQ_0566
Figure 12_A0101_SEQ_0567
Figure 12_A0101_SEQ_0568
Figure 12_A0101_SEQ_0569
Figure 12_A0101_SEQ_0570
Figure 12_A0101_SEQ_0571
Figure 12_A0101_SEQ_0572
Figure 12_A0101_SEQ_0573
Figure 12_A0101_SEQ_0574
Figure 12_A0101_SEQ_0575
Figure 12_A0101_SEQ_0576
Figure 12_A0101_SEQ_0577
Figure 12_A0101_SEQ_0578
Figure 12_A0101_SEQ_0579
Figure 12_A0101_SEQ_0580
Figure 12_A0101_SEQ_0581
Figure 12_A0101_SEQ_0582
Figure 12_A0101_SEQ_0583
Figure 12_A0101_SEQ_0584
Figure 12_A0101_SEQ_0585
Figure 12_A0101_SEQ_0586
Figure 12_A0101_SEQ_0587
Figure 12_A0101_SEQ_0588
Figure 12_A0101_SEQ_0589
Figure 12_A0101_SEQ_0590
Figure 12_A0101_SEQ_0591
Figure 12_A0101_SEQ_0592
Figure 12_A0101_SEQ_0593
Figure 12_A0101_SEQ_0594
Figure 12_A0101_SEQ_0595
Figure 12_A0101_SEQ_0596
Figure 12_A0101_SEQ_0597
Figure 12_A0101_SEQ_0598
Figure 12_A0101_SEQ_0599
Figure 12_A0101_SEQ_0600
Figure 12_A0101_SEQ_0601
Figure 12_A0101_SEQ_0602
Figure 12_A0101_SEQ_0603
Figure 12_A0101_SEQ_0604
Figure 12_A0101_SEQ_0605
Figure 12_A0101_SEQ_0606
Figure 12_A0101_SEQ_0607
Figure 12_A0101_SEQ_0608
Figure 12_A0101_SEQ_0609
Figure 12_A0101_SEQ_0610
Figure 12_A0101_SEQ_0611
Figure 12_A0101_SEQ_0612
Figure 12_A0101_SEQ_0613
Figure 12_A0101_SEQ_0614
Figure 12_A0101_SEQ_0615
Figure 12_A0101_SEQ_0616
Figure 12_A0101_SEQ_0617
Figure 12_A0101_SEQ_0618
Figure 12_A0101_SEQ_0619
Figure 12_A0101_SEQ_0620
Figure 12_A0101_SEQ_0621
Figure 12_A0101_SEQ_0622
Figure 12_A0101_SEQ_0623
Figure 12_A0101_SEQ_0624
Figure 12_A0101_SEQ_0625
Figure 12_A0101_SEQ_0626
Figure 12_A0101_SEQ_0627
Figure 12_A0101_SEQ_0628
Figure 12_A0101_SEQ_0629
Figure 12_A0101_SEQ_0630
Figure 12_A0101_SEQ_0631
Figure 12_A0101_SEQ_0632
Figure 12_A0101_SEQ_0633
Figure 12_A0101_SEQ_0634
Figure 12_A0101_SEQ_0635
Figure 12_A0101_SEQ_0636
Figure 12_A0101_SEQ_0637
Figure 12_A0101_SEQ_0638
Figure 12_A0101_SEQ_0639
Figure 12_A0101_SEQ_0640
Figure 12_A0101_SEQ_0641
Figure 12_A0101_SEQ_0642
Figure 12_A0101_SEQ_0643
Figure 12_A0101_SEQ_0644
Figure 12_A0101_SEQ_0645
Figure 12_A0101_SEQ_0646
Figure 12_A0101_SEQ_0647
Figure 12_A0101_SEQ_0648
Figure 12_A0101_SEQ_0649
Figure 12_A0101_SEQ_0650
Figure 12_A0101_SEQ_0651
Figure 12_A0101_SEQ_0652
Figure 12_A0101_SEQ_0653
Figure 12_A0101_SEQ_0654
Figure 12_A0101_SEQ_0655
Figure 12_A0101_SEQ_0656
Figure 12_A0101_SEQ_0657
Figure 12_A0101_SEQ_0658
Figure 12_A0101_SEQ_0659
Figure 12_A0101_SEQ_0660
Figure 12_A0101_SEQ_0661
Figure 12_A0101_SEQ_0662
Figure 12_A0101_SEQ_0663
Figure 12_A0101_SEQ_0664
Figure 12_A0101_SEQ_0665
Figure 12_A0101_SEQ_0666
Figure 12_A0101_SEQ_0667
Figure 12_A0101_SEQ_0668
Figure 12_A0101_SEQ_0669
Figure 12_A0101_SEQ_0670
Figure 12_A0101_SEQ_0671
Figure 12_A0101_SEQ_0672
Figure 12_A0101_SEQ_0673
Figure 12_A0101_SEQ_0674
Figure 12_A0101_SEQ_0675
Figure 12_A0101_SEQ_0676
Figure 12_A0101_SEQ_0677
Figure 12_A0101_SEQ_0678
Figure 12_A0101_SEQ_0679
Figure 12_A0101_SEQ_0680
Figure 12_A0101_SEQ_0681
Figure 12_A0101_SEQ_0682
Figure 12_A0101_SEQ_0683
Figure 12_A0101_SEQ_0684
Figure 12_A0101_SEQ_0685
Figure 12_A0101_SEQ_0686
Figure 12_A0101_SEQ_0687
Figure 12_A0101_SEQ_0688
Figure 12_A0101_SEQ_0689
Figure 12_A0101_SEQ_0690
Figure 12_A0101_SEQ_0691
Figure 12_A0101_SEQ_0692
Figure 12_A0101_SEQ_0693
Figure 12_A0101_SEQ_0694
Figure 12_A0101_SEQ_0695
Figure 12_A0101_SEQ_0696
Figure 12_A0101_SEQ_0697
Figure 12_A0101_SEQ_0698
Figure 12_A0101_SEQ_0699
Figure 12_A0101_SEQ_0700
Figure 12_A0101_SEQ_0701
Figure 12_A0101_SEQ_0702
Figure 12_A0101_SEQ_0703
Figure 12_A0101_SEQ_0704
Figure 12_A0101_SEQ_0705
Figure 12_A0101_SEQ_0706
Figure 12_A0101_SEQ_0707
Figure 12_A0101_SEQ_0708
Figure 12_A0101_SEQ_0709
Figure 12_A0101_SEQ_0710
Figure 12_A0101_SEQ_0711
Figure 12_A0101_SEQ_0712
Figure 12_A0101_SEQ_0713
Figure 12_A0101_SEQ_0714
Figure 12_A0101_SEQ_0715
Figure 12_A0101_SEQ_0716
Figure 12_A0101_SEQ_0717
Figure 12_A0101_SEQ_0718
Figure 12_A0101_SEQ_0719
Figure 12_A0101_SEQ_0720
Figure 12_A0101_SEQ_0721
Figure 12_A0101_SEQ_0722
Figure 12_A0101_SEQ_0723
Figure 12_A0101_SEQ_0724
Figure 12_A0101_SEQ_0725
Figure 12_A0101_SEQ_0726
Figure 12_A0101_SEQ_0727
Figure 12_A0101_SEQ_0728
Figure 12_A0101_SEQ_0729
Figure 12_A0101_SEQ_0730
Figure 12_A0101_SEQ_0731
Figure 12_A0101_SEQ_0732
Figure 12_A0101_SEQ_0733
Figure 12_A0101_SEQ_0734
Figure 12_A0101_SEQ_0735
Figure 12_A0101_SEQ_0736
Figure 12_A0101_SEQ_0737
Figure 12_A0101_SEQ_0738
Figure 12_A0101_SEQ_0739
Figure 12_A0101_SEQ_0740
Figure 12_A0101_SEQ_0741
Figure 12_A0101_SEQ_0742
Figure 12_A0101_SEQ_0743
Figure 12_A0101_SEQ_0744
Figure 12_A0101_SEQ_0745
Figure 12_A0101_SEQ_0746
Figure 12_A0101_SEQ_0747
Figure 12_A0101_SEQ_0748
Figure 12_A0101_SEQ_0749
Figure 12_A0101_SEQ_0750
Figure 12_A0101_SEQ_0751
Figure 12_A0101_SEQ_0752
Figure 12_A0101_SEQ_0753
Figure 12_A0101_SEQ_0754
Figure 12_A0101_SEQ_0755
Figure 12_A0101_SEQ_0756
Figure 12_A0101_SEQ_0757
Figure 12_A0101_SEQ_0758
Figure 12_A0101_SEQ_0759
Figure 12_A0101_SEQ_0760
Figure 12_A0101_SEQ_0761
Figure 12_A0101_SEQ_0762
Figure 12_A0101_SEQ_0763
Figure 12_A0101_SEQ_0764
Figure 12_A0101_SEQ_0765
Figure 12_A0101_SEQ_0766
Figure 12_A0101_SEQ_0767
Figure 12_A0101_SEQ_0768
Figure 12_A0101_SEQ_0769
Figure 12_A0101_SEQ_0770
Figure 12_A0101_SEQ_0771
Figure 12_A0101_SEQ_0772
Figure 12_A0101_SEQ_0773
Figure 12_A0101_SEQ_0774
Figure 12_A0101_SEQ_0775
Figure 12_A0101_SEQ_0776
Figure 12_A0101_SEQ_0777
Figure 12_A0101_SEQ_0778
Figure 12_A0101_SEQ_0779
Figure 12_A0101_SEQ_0780
Figure 12_A0101_SEQ_0781
Figure 12_A0101_SEQ_0782
Figure 12_A0101_SEQ_0783
Figure 12_A0101_SEQ_0784
Figure 12_A0101_SEQ_0785
Figure 12_A0101_SEQ_0786
Figure 12_A0101_SEQ_0787
Figure 12_A0101_SEQ_0788
Figure 12_A0101_SEQ_0789
Figure 12_A0101_SEQ_0790
Figure 12_A0101_SEQ_0791
Figure 12_A0101_SEQ_0792
Figure 12_A0101_SEQ_0793
Figure 12_A0101_SEQ_0794
Figure 12_A0101_SEQ_0795
Figure 12_A0101_SEQ_0796
Figure 12_A0101_SEQ_0797
Figure 12_A0101_SEQ_0798
Figure 12_A0101_SEQ_0799
Figure 12_A0101_SEQ_0800
Figure 12_A0101_SEQ_0801
Figure 12_A0101_SEQ_0802
Figure 12_A0101_SEQ_0803
Figure 12_A0101_SEQ_0804
Figure 12_A0101_SEQ_0805
Figure 12_A0101_SEQ_0806
Figure 12_A0101_SEQ_0807
Figure 12_A0101_SEQ_0808
Figure 12_A0101_SEQ_0809
Figure 12_A0101_SEQ_0810
Figure 12_A0101_SEQ_0811
Figure 12_A0101_SEQ_0812
Figure 12_A0101_SEQ_0813
Figure 12_A0101_SEQ_0814
Figure 12_A0101_SEQ_0815
Figure 12_A0101_SEQ_0816
Figure 12_A0101_SEQ_0817
Figure 12_A0101_SEQ_0818
Figure 12_A0101_SEQ_0819
Figure 12_A0101_SEQ_0820
Figure 12_A0101_SEQ_0821
Figure 12_A0101_SEQ_0822
Figure 12_A0101_SEQ_0823
Figure 12_A0101_SEQ_0824
Figure 12_A0101_SEQ_0825
Figure 12_A0101_SEQ_0826
Figure 12_A0101_SEQ_0827
Figure 12_A0101_SEQ_0828
Figure 12_A0101_SEQ_0829
Figure 12_A0101_SEQ_0830
Figure 12_A0101_SEQ_0831
Figure 12_A0101_SEQ_0832
Figure 12_A0101_SEQ_0833
Figure 12_A0101_SEQ_0834
Figure 12_A0101_SEQ_0835
Figure 12_A0101_SEQ_0836
Figure 12_A0101_SEQ_0837
Figure 12_A0101_SEQ_0838
Figure 12_A0101_SEQ_0839
Figure 12_A0101_SEQ_0840
Figure 12_A0101_SEQ_0841
Figure 12_A0101_SEQ_0842
Figure 12_A0101_SEQ_0843
Figure 12_A0101_SEQ_0844
Figure 12_A0101_SEQ_0845
Figure 12_A0101_SEQ_0846

Claims (13)

  1. 一種用於偵測代表群體中子群之染色體狀態的方法，其包含判定與該染色體狀態相關之染色體相互作用存在或不存在於基因體之經限定區域內；及 其中該染色體相互作用業經視情況藉由判定哪些染色體相互作用與對應於該群體之該子群之染色體狀態相關的方法加以鑑別，包含使來自具有不同染色體狀態之子群之第一組核酸與第二組索引核酸接觸，且允許互補序列雜交，其中該第一組核酸及該第二組核酸中之該等核酸代表經接合產物，該經接合產物包含來自在染色體相互作用中聚集在一起的兩個染色體區域的序列，且其中該第一組核酸與該第二組核酸之間的雜交圖案允許判定哪些染色體相互作用對該子群具有特異性；及 其中該子群與泛自閉症障礙(autism spectrum disorder；ASD)之預後相關，且該染色體相互作用： (i)     存在於表1至表4中之任一者中所列之區域或基因中之任一者中；及/或 (ii)    對應於由表1至表4中之任一者中所示之任何探針代表的染色體相互作用中之任一者，及/或 (iii)   存在於包含或側接(i)或(ii)之4,000個鹼基區域中。
  2. 如請求項1之方法，其中至少10種如以下中所代表之染色體相互作用係經分類： 表1，或 表2，或 表3，或 表4。
  3. 如請求項1或2之方法，其中至少1、5、8或10種如表8、表9或表10中所代表之染色體相互作用係經分類。
  4. 如前述請求項中任一項之方法，其中至少1、5、8、10、15或20種如表10中所代表之染色體相互作用係經分類。
  5. 如前述請求項中任一項之方法，其中該等染色體相互作用係經分類： 在來自個體之樣品中，及/或 藉由偵測在該等染色體相互作用之位點處存在或不存在DNA環，及/或 偵測存在或不存在以染色體構形中結合在一起的染色體之遠端區域，及/或 藉由偵測在該分類期間所產生之經接合核酸及其包含各自對應於在該染色體相互作用中聚集在一起的該染色體之該等區域之兩個區域之存在，其中對該經接合核酸之偵測較佳地係(i)藉由與表1、表2、表3或表4中之任一者中提及之特異性探針序列中之任一者具有至少70%一致性的探針及/或(ii)藉由與表1、表2、表3或表4中之任何引子對具有至少70%一致性的引子對進行。
  6. 如前述請求項中任一項之方法，其中對該染色體相互作用之偵測係藉由包含以下步驟之方法進行： (i)     使在染色體相互作用中聚集在一起的染色體區域交聯； (ii)    視情況藉由用酶進行限制性消化裂解使該等經交聯區域經受裂解；及 (iii)   使該等經交聯裂解DNA末端接合以形成該第一組核酸(特定言之包含經接合DNA)； 偵測存在或不存在該經接合DNA。
  7. 如前述請求項中任一項之方法，其經實施以判定ASD之嚴重程度或類型。
  8. 如前述請求項中任一項之方法，其中對輕度ASD具有特異性之至少1、5、8、10、15或20種染色體相互作用係經分類。
  9. 如前述請求項中任一項之方法，其中對重度ASD具有特異性之至少1、5、8、10、15或20種染色體相互作用係經分類。
  10. 如前述請求項中任一項之方法，其中分類或偵測包含藉由使用能夠擴增該經接合產物之引子及在PCR反應期間結合接合位點之探針的定量PCR (qPCR)進行該經接合產物之特異性偵測，其中該探針包含與來自在該染色體相互作用中聚集在一起的該等染色體區域中之每一者的序列互補的序列，其中較佳地，該探針包含： 寡核苷酸，其特異性結合於該經接合產物，及/或 螢光團，其共價連接至該寡核苷酸之5'末端，及/或 淬滅劑，其共價連接至該寡核苷酸之3'末端，及 視情況地 該螢光團係選自HEX、德克薩斯紅(Texas Red)及FAM；及/或 該探針包含長度為10至40個核苷酸鹼基，較佳地長度為20至30個核苷酸鹼基的核酸序列。
  11. 如前述請求項中任一項之方法，其中： 該方法之結果係以報告提供，及/或 該方法之結果係用以選擇患者治療計劃，且較佳地用於選擇用於個體之特定療法。
  12. 如前述請求項中任一項之方法，其中該個體已基於身體特徵、風險因素或症狀預先選擇，且較佳地係基於具有以下疾病之症狀或風險因素：自閉症、兒童自閉症、亞斯伯格症候群(Asperger's syndrome)、PDD-NOS (廣泛性發展障礙(Pervasive Development Disorder))、兒童崩解症(childhood disintegrative disorder)或成癮。
  13. 一種用於治療個體中ASD之方法的治療劑，該個體已藉由如前述請求項中任一項之方法鑑別為需要該治療劑。
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CN113984482B (zh) * 2021-12-24 2022-03-15 北京仁基源医学研究院有限公司 一种用于制备超高分辨染色体的复合试剂及其应用方法

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