TW202120104A - 用於治療apoc3相關疾病及病症之方法 - Google Patents

用於治療apoc3相關疾病及病症之方法 Download PDF

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TW202120104A
TW202120104A TW109126581A TW109126581A TW202120104A TW 202120104 A TW202120104 A TW 202120104A TW 109126581 A TW109126581 A TW 109126581A TW 109126581 A TW109126581 A TW 109126581A TW 202120104 A TW202120104 A TW 202120104A
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Taiwan
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dose
pharmaceutical composition
apoc3
apoc3 rnai
administered
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TW109126581A
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English (en)
Chinese (zh)
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布魯斯 齊文
詹姆士 Ｃ 漢彌頓
史黛西 梅爾柯斯特
李
銳 朱
濤 裴
史蒂芬 坎納
素珍 黃
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美商愛羅海德製藥公司
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Publication of TW202120104A publication Critical patent/TW202120104A/zh

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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TW109126581A 2019-08-05 2020-08-05 用於治療apoc3相關疾病及病症之方法 TW202120104A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962883046P 2019-08-05 2019-08-05
US62/883,046 2019-08-05
US201962936559P 2019-11-17 2019-11-17
US62/936,559 2019-11-17
US202062970613P 2020-02-05 2020-02-05
US62/970,613 2020-02-05

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Publication Number Publication Date
TW202120104A true TW202120104A (zh) 2021-06-01

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TW109126581A TW202120104A (zh) 2019-08-05 2020-08-05 用於治療apoc3相關疾病及病症之方法

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US (1) US20220152079A1 (enExample)
EP (1) EP4010075A4 (enExample)
JP (2) JP7829478B2 (enExample)
KR (1) KR20220044551A (enExample)
CN (1) CN114555188A (enExample)
AU (2) AU2020324974B2 (enExample)
CA (1) CA3147725A1 (enExample)
MX (1) MX2022001460A (enExample)
TW (1) TW202120104A (enExample)
WO (1) WO2021026150A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20170056B1 (ar) * 2016-09-02 2021-08-17 Arrowhead Pharmaceuticals Inc مركبات ترابطية مستهدفة
CN114934074A (zh) * 2022-06-01 2022-08-23 北京大学 一种ApoC3基因敲除仓鼠模型的构建方法
WO2024245381A1 (zh) 2023-06-01 2024-12-05 广东东阳光药业股份有限公司 一种新型的双链siRNA、其缀合物及其用途
WO2026049536A1 (en) * 2024-08-30 2026-03-05 Olix Pharmaceuticals, Inc. RNAi AGENT TARGETING APOC3 GENE AND USE THEREOF

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2505292C2 (ru) * 2009-02-10 2014-01-27 Амарин Фармасьютикалз Айрлэнд Лимитед Способы лечения гипертриглицеридемии
CA2839573A1 (en) 2011-06-21 2012-12-27 Alnylam Pharmaceuticals, Inc. Angiopoietin-like 3 (angptl3) irna compositions and methods of use thereof
EP2723756B1 (en) * 2011-06-21 2020-03-11 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibition of expression of apolipoprotein c-iii (apoc3) genes
WO2016081444A1 (en) 2014-11-17 2016-05-26 Alnylam Pharmaceuticals, Inc. Apolipoprotein c3 (apoc3) irna compositions and methods of use thereof
TWI865997B (zh) * 2016-12-16 2024-12-11 美商阿尼拉製藥公司 使用甲狀腺素運載蛋白（ＴＴＲ）ｉＲＮＡ組成物於治療或預防ＴＴＲ相關疾病之方法
CN111164091B (zh) 2017-06-02 2025-01-07 波涛生命科学有限公司 寡核苷酸组合物及其使用方法
SG11201912178VA (en) * 2017-09-11 2020-01-30 Arrowhead Pharmaceuticals Inc Rnai agents and compositions for inhibiting expression of apolipoprotein c-iii (apoc3)
CN118291456A (zh) * 2017-12-01 2024-07-05 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途

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CN114555188A (zh) 2022-05-27
JP7829478B2 (ja) 2026-03-13
AU2026208045A1 (en) 2026-08-13
JP2022543136A (ja) 2022-10-07
US20220152079A1 (en) 2022-05-19
KR20220044551A (ko) 2022-04-08
AU2020324974B2 (en) 2026-04-30
MX2022001460A (es) 2022-02-22
EP4010075A4 (en) 2023-11-15
WO2021026150A1 (en) 2021-02-11
JP2025061882A (ja) 2025-04-11
CA3147725A1 (en) 2021-02-11
EP4010075A1 (en) 2022-06-15
AU2020324974A1 (en) 2022-02-24

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