TW202118779A - 鑑定ｔ細胞受體之方法 - Google Patents

鑑定ｔ細胞受體之方法 Download PDF

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Publication number
TW202118779A
TW202118779A TW109125671A TW109125671A TW202118779A TW 202118779 A TW202118779 A TW 202118779A TW 109125671 A TW109125671 A TW 109125671A TW 109125671 A TW109125671 A TW 109125671A TW 202118779 A TW202118779 A TW 202118779A
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Taiwan
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dpb1
amino acid
drb1
dqb1
seq
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TW109125671A
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English (en)
Chinese (zh)
Inventor
平野直人
中津川宗秀
山下勇毅
菅田謙治
穆罕亞旭 拉曼
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大學健康網絡
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Publication of TW202118779A publication Critical patent/TW202118779A/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/7051—T-cell receptor (TcR)-CD3 complex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539—MHC-molecules, e.g. HLA-molecules

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TW109125671A 2019-07-30 2020-07-29 鑑定ｔ細胞受體之方法 TW202118779A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962880492P 2019-07-30 2019-07-30
US62/880,492 2019-07-30
US202063029103P 2020-05-22 2020-05-22
US63/029,103 2020-05-22

Publications (1)

Publication Number Publication Date
TW202118779A true TW202118779A (zh) 2021-05-16

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ID=74228602

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109125671A TW202118779A (zh) 2019-07-30 2020-07-29 鑑定ｔ細胞受體之方法

Country Status (11)

Country Link
US (1) US20220291215A1 (cg-RX-API-DMAC10.html)
EP (1) EP4004546A4 (cg-RX-API-DMAC10.html)
JP (2) JP7724203B2 (cg-RX-API-DMAC10.html)
KR (1) KR102985224B1 (cg-RX-API-DMAC10.html)
CN (1) CN114761802B (cg-RX-API-DMAC10.html)
AU (1) AU2020321710A1 (cg-RX-API-DMAC10.html)
CA (1) CA3146290A1 (cg-RX-API-DMAC10.html)
IL (1) IL290226A (cg-RX-API-DMAC10.html)
MX (1) MX2022001204A (cg-RX-API-DMAC10.html)
TW (1) TW202118779A (cg-RX-API-DMAC10.html)
WO (1) WO2021019476A1 (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020231693A1 (en) 2019-03-04 2021-09-30 University Health Network T cell receptors and methods of use thereof
TWI881991B (zh) * 2019-07-30 2025-05-01 大學健康網絡 Ｉｉ類ｍｈｃ分子及其使用方法
TW202116797A (zh) 2019-07-30 2021-05-01 大學健康網絡 Ｉｉ類ｍｈｃ分子及其使用方法
CN118662607B (zh) * 2023-03-15 2026-07-07 中国科学院上海药物研究所 抑制过激炎性反应的蛋白及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012120488A (ja) * 2010-12-09 2012-06-28 Univ Of Tokyo 新規安定化組換えｍｈｃタンパク質
AU2018335274B2 (en) * 2017-09-20 2025-02-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services HLA class II–restricted T cell receptors against mutated RAS
TW202116797A (zh) * 2019-07-30 2021-05-01 大學健康網絡 Ｉｉ類ｍｈｃ分子及其使用方法

Also Published As

Publication number Publication date
CN114761802A (zh) 2022-07-15
CN114761802B (zh) 2026-04-28
WO2021019476A1 (en) 2021-02-04
JP2025166836A (ja) 2025-11-06
KR20220052941A (ko) 2022-04-28
JP7724203B2 (ja) 2025-08-15
EP4004546A1 (en) 2022-06-01
MX2022001204A (es) 2022-05-03
JP2022542445A (ja) 2022-10-03
US20220291215A1 (en) 2022-09-15
IL290226A (en) 2022-03-01
KR102985224B1 (ko) 2026-07-02
CA3146290A1 (en) 2021-02-04
EP4004546A4 (en) 2024-10-09
AU2020321710A1 (en) 2022-03-03

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