TW202108561A - 用於治療痛風或高尿酸血症之化合物 - Google Patents

用於治療痛風或高尿酸血症之化合物 Download PDF

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Publication number
TW202108561A
TW202108561A TW109115899A TW109115899A TW202108561A TW 202108561 A TW202108561 A TW 202108561A TW 109115899 A TW109115899 A TW 109115899A TW 109115899 A TW109115899 A TW 109115899A TW 202108561 A TW202108561 A TW 202108561A
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TW
Taiwan
Prior art keywords
compound
effective amount
therapeutically effective
pharmaceutically acceptable
pharmaceutical composition
Prior art date
Application number
TW109115899A
Other languages
English (en)
Chinese (zh)
Inventor
順啟 顏
立天 葉
戎子 顏
贊聰 沈
Original Assignee
美商安索治療公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美商安索治療公司 filed Critical 美商安索治療公司
Publication of TW202108561A publication Critical patent/TW202108561A/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
TW109115899A 2019-05-14 2020-05-13 用於治療痛風或高尿酸血症之化合物 TW202108561A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962847519P 2019-05-14 2019-05-14
US62/847,519 2019-05-14

Publications (1)

Publication Number Publication Date
TW202108561A true TW202108561A (zh) 2021-03-01

Family

ID=73288915

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109115899A TW202108561A (zh) 2019-05-14 2020-05-13 用於治療痛風或高尿酸血症之化合物

Country Status (14)

Country Link
US (2) US20220242841A1 (enExample)
EP (1) EP3968989A4 (enExample)
JP (1) JP7656548B2 (enExample)
KR (1) KR102971948B1 (enExample)
CN (1) CN113874014A (enExample)
AU (2) AU2020274165A1 (enExample)
BR (1) BR112021022843A2 (enExample)
CA (1) CA3140412A1 (enExample)
IL (1) IL288034B2 (enExample)
MA (1) MA55973A (enExample)
MX (1) MX2021013980A (enExample)
SG (1) SG11202112562XA (enExample)
TW (1) TW202108561A (enExample)
WO (1) WO2020232156A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113164439A (zh) 2018-12-06 2021-07-23 安索治疗公司 用于治疗或预防痛风或高尿酸血症的方法
JP2022511800A (ja) 2018-12-06 2022-02-01 アースローシ セラピューティクス,インク. 痛風または高尿酸血症を処置または予防するための化合物の結晶形態
KR20230024354A (ko) * 2020-06-10 2023-02-20 아쓰로시 테라퓨틱스, 인크. 만성 신장 질환을 치료 또는 예방하는 방법
WO2023058975A1 (ko) * 2021-10-07 2023-04-13 (주)이노보테라퓨틱스 벤조퓨라닐 히드록시페닐 메타논 유도체를 포함하는 hsp47 억제용 약학 조성물
WO2023098872A1 (en) * 2021-12-02 2023-06-08 Arthrosi Therapeutics, Inc. Crystalline forms of a compound for treating or preventing gout or hyperuricemia
WO2023125667A1 (en) * 2021-12-30 2023-07-06 Arthrosi Therapeutics, Inc. Preparation of a compound for the treatment of gout or hyperuricemia
US20250242050A1 (en) 2024-01-31 2025-07-31 The Industry & Academic Cooperation In Chungnam National University (Iac) Composition for treating gout containing cyclodextrin-conjugated polymer nano-drug and method for treating gout

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9962362B2 (en) * 2012-03-29 2018-05-08 Children's Hospital Medical Center Use of small molecule inhibitors targeting EYA tyrosine phosphatase
AU2017298142B2 (en) * 2016-07-18 2021-11-11 Arthrosi Therapeutics, Inc. Compounds, compositions and methods for treating or preventing a symptom associated with gout or hyperuricemia
WO2019195118A1 (en) * 2018-04-03 2019-10-10 Children's Hospital Medical Center Inhibitors of eya3-protein tyrosine phosphatase in dna damage repair signaling of pulmonary arterial hypertension
JP2022511800A (ja) * 2018-12-06 2022-02-01 アースローシ セラピューティクス,インク. 痛風または高尿酸血症を処置または予防するための化合物の結晶形態

Also Published As

Publication number Publication date
IL288034A (en) 2022-01-01
AU2026202224A1 (en) 2026-04-09
CA3140412A1 (en) 2020-11-19
JP2022533958A (ja) 2022-07-27
BR112021022843A2 (pt) 2022-03-03
EP3968989A1 (en) 2022-03-23
SG11202112562XA (en) 2021-12-30
IL288034B1 (en) 2026-04-01
AU2020274165A1 (en) 2022-01-06
MX2021013980A (es) 2022-04-01
US20260200884A1 (en) 2026-07-16
KR20220016105A (ko) 2022-02-08
IL288034B2 (en) 2026-08-01
US20220242841A1 (en) 2022-08-04
JP7656548B2 (ja) 2025-04-03
KR102971948B1 (ko) 2026-06-01
WO2020232156A1 (en) 2020-11-19
CN113874014A (zh) 2021-12-31
MA55973A (fr) 2022-03-23
EP3968989A4 (en) 2022-12-28

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