CN113874014A - 用于治疗痛风或高尿酸血症的化合物 - Google Patents
用于治疗痛风或高尿酸血症的化合物 Download PDFInfo
- Publication number
- CN113874014A CN113874014A CN202080035809.1A CN202080035809A CN113874014A CN 113874014 A CN113874014 A CN 113874014A CN 202080035809 A CN202080035809 A CN 202080035809A CN 113874014 A CN113874014 A CN 113874014A
- Authority
- CN
- China
- Prior art keywords
- compound
- effective amount
- therapeutically effective
- pharmaceutically acceptable
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962847519P | 2019-05-14 | 2019-05-14 | |
| US62/847,519 | 2019-05-14 | ||
| PCT/US2020/032725 WO2020232156A1 (en) | 2019-05-14 | 2020-05-13 | Compound for treating gout or hyperuricemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113874014A true CN113874014A (zh) | 2021-12-31 |
Family
ID=73288915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080035809.1A Pending CN113874014A (zh) | 2019-05-14 | 2020-05-13 | 用于治疗痛风或高尿酸血症的化合物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220242841A1 (enExample) |
| EP (1) | EP3968989A4 (enExample) |
| JP (1) | JP7656548B2 (enExample) |
| KR (1) | KR20220016105A (enExample) |
| CN (1) | CN113874014A (enExample) |
| AU (2) | AU2020274165A1 (enExample) |
| BR (1) | BR112021022843A2 (enExample) |
| CA (1) | CA3140412A1 (enExample) |
| IL (1) | IL288034B1 (enExample) |
| MA (1) | MA55973A (enExample) |
| MX (1) | MX2021013980A (enExample) |
| SG (1) | SG11202112562XA (enExample) |
| TW (1) | TW202108561A (enExample) |
| WO (1) | WO2020232156A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3121624A1 (en) | 2018-12-06 | 2020-06-11 | Arthrosi Therapeutics, Inc. | Methods for treating or preventing gout or hyperuricemia |
| US12145917B2 (en) | 2018-12-06 | 2024-11-19 | Arthrosi Therapeutics, Inc. | Crystalline forms of a compound for treating or preventing gout or hyperuricemia |
| WO2021252630A1 (en) * | 2020-06-10 | 2021-12-16 | Arthrosi Therapeutics, Inc. | Methods for treating or preventing chronic kidney disease |
| KR20230050232A (ko) * | 2021-10-07 | 2023-04-14 | 주식회사 이노보테라퓨틱스 | 벤조퓨라닐 히드록시페닐 메타논 유도체를 포함하는 hsp47 억제용 약학 조성물 |
| US20250066316A1 (en) * | 2021-12-02 | 2025-02-27 | Arthrosi Therapeutics, Inc. | Crystalline forms of a compound for treating or preventing gout or hyperuricemia |
| CN118974028A (zh) * | 2021-12-30 | 2024-11-15 | 广州瑞安博医药科技有限公司 | 用于治疗痛风或高尿酸血症的化合物的制备 |
| US20250242050A1 (en) | 2024-01-31 | 2025-07-31 | The Industry & Academic Cooperation In Chungnam National University (Iac) | Composition for treating gout containing cyclodextrin-conjugated polymer nano-drug and method for treating gout |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018017368A1 (en) * | 2016-07-18 | 2018-01-25 | Arthrosi Therapeutics, Llc | Compounds, compositions and methods for treating or preventing a sympton associated with gout or hyperuricemia |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9962362B2 (en) * | 2012-03-29 | 2018-05-08 | Children's Hospital Medical Center | Use of small molecule inhibitors targeting EYA tyrosine phosphatase |
| WO2019195118A1 (en) * | 2018-04-03 | 2019-10-10 | Children's Hospital Medical Center | Inhibitors of eya3-protein tyrosine phosphatase in dna damage repair signaling of pulmonary arterial hypertension |
| US12145917B2 (en) * | 2018-12-06 | 2024-11-19 | Arthrosi Therapeutics, Inc. | Crystalline forms of a compound for treating or preventing gout or hyperuricemia |
-
2020
- 2020-05-13 EP EP20804806.6A patent/EP3968989A4/en active Pending
- 2020-05-13 KR KR1020217041035A patent/KR20220016105A/ko active Pending
- 2020-05-13 TW TW109115899A patent/TW202108561A/zh unknown
- 2020-05-13 AU AU2020274165A patent/AU2020274165A1/en not_active Abandoned
- 2020-05-13 MX MX2021013980A patent/MX2021013980A/es unknown
- 2020-05-13 CA CA3140412A patent/CA3140412A1/en active Pending
- 2020-05-13 CN CN202080035809.1A patent/CN113874014A/zh active Pending
- 2020-05-13 WO PCT/US2020/032725 patent/WO2020232156A1/en not_active Ceased
- 2020-05-13 SG SG11202112562XA patent/SG11202112562XA/en unknown
- 2020-05-13 MA MA055973A patent/MA55973A/fr unknown
- 2020-05-13 JP JP2021568229A patent/JP7656548B2/ja active Active
- 2020-05-13 US US17/610,673 patent/US20220242841A1/en active Pending
- 2020-05-13 IL IL288034A patent/IL288034B1/en unknown
- 2020-05-13 BR BR112021022843A patent/BR112021022843A2/pt unknown
-
2026
- 2026-03-23 AU AU2026202224A patent/AU2026202224A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018017368A1 (en) * | 2016-07-18 | 2018-01-25 | Arthrosi Therapeutics, Llc | Compounds, compositions and methods for treating or preventing a sympton associated with gout or hyperuricemia |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2020274165A1 (en) | 2022-01-06 |
| EP3968989A4 (en) | 2022-12-28 |
| SG11202112562XA (en) | 2021-12-30 |
| KR20220016105A (ko) | 2022-02-08 |
| BR112021022843A2 (pt) | 2022-03-03 |
| TW202108561A (zh) | 2021-03-01 |
| IL288034B1 (en) | 2026-04-01 |
| CA3140412A1 (en) | 2020-11-19 |
| IL288034A (en) | 2022-01-01 |
| JP2022533958A (ja) | 2022-07-27 |
| US20220242841A1 (en) | 2022-08-04 |
| WO2020232156A1 (en) | 2020-11-19 |
| MA55973A (fr) | 2022-03-23 |
| JP7656548B2 (ja) | 2025-04-03 |
| MX2021013980A (es) | 2022-04-01 |
| AU2026202224A1 (en) | 2026-04-09 |
| EP3968989A1 (en) | 2022-03-23 |
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| US20250059150A1 (en) | Crystalline forms of a compound for treating or preventing gout or hyperuricemia | |
| CN113874014A (zh) | 用于治疗痛风或高尿酸血症的化合物 | |
| JP7528080B2 (ja) | 痛風または高尿酸血症を処置または予防するための方法 | |
| WO2023098872A1 (en) | Crystalline forms of a compound for treating or preventing gout or hyperuricemia | |
| HK40060723A (en) | Compound for treating gout or hyperuricemia | |
| KR102956127B1 (ko) | 통풍 또는 고뇨산혈증의 치료 또는 예방 방법 | |
| HK40056575A (en) | Methods for treating or preventing gout or hyperuricemia | |
| EA049585B1 (ru) | Соединение для лечения подагры или гиперурикемии | |
| HK40056574A (en) | Crystalline forms of a compound for treating or preventing gout or hyperuricemia | |
| HK40056574B (zh) | 用於治疗或预防痛风或高尿酸血症的化合物的晶型 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20211230 Address after: Room 1501, No. 27, Huanyu 1st Road, Guangzhou International Biological Island, Huangpu District, Guangzhou, Guangdong Applicant after: Guangzhou ruianbo Pharmaceutical Technology Co.,Ltd. Address before: California, USA Applicant before: ARTHROSI THERAPEUTICS, Inc. |
|
| TA01 | Transfer of patent application right | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 40060723 Country of ref document: HK |
|
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20211231 |
|
| RJ01 | Rejection of invention patent application after publication |