TW202108116A - Sunscreen cosmetic composition having sebum absorbing ability - Google Patents

Abstract

The present disclosure relates to a cosmetic composition for improving the sebum-controlling ability of a sunscreen which comprises bowl-like non-porous microparticles comprising a polymer matrix in which bis-ethylhexyloxyphenol methoxylphenyl triazine is stabilized. The composition comprises hardly soluble bis-ethylhexyloxyphenol methoxylphenyl triazine in the form of bowl-like microparticles, and thus has high sebum absorption and shows a light and fresh feeling of use.

Description

Sunscreen cosmetic composition with sebum absorption capacity

The present disclosure relates to a sebum control cosmetic composition. Cross-reference of related applications

This application claims the priority of Korean Patent Application No. 10-2019-0057114 filed in Korea on May 15, 2019, and the disclosure of this application is incorporated herein by reference.

Sebum is the secretion discharged from the sebaceous glands and includes cholesterol, fatty acids and ester compounds. Sebum is used to prevent the surface of the skin from drying out, but it can cause shiny or mottled makeup on the face. Therefore, many studies have been conducted on products that can control the amount of skin sebum so as to maintain a matte and smooth application state throughout the day in the case of sunscreens or cosmetic compositions. In order to control the amount of skin sebum, non-porous powders or porous spherical powders are mostly used. The non-porous spherical powder exhibits low sebum absorption capacity. In the case of porous powder particles, the sebum absorption capacity is high depending on the high immersion amount. However, these porous powder particles have an excessively large surface area, resulting in a high dissolution probability of stable components in the particle matrix. In addition, as compared with non-porous particles, these porous powder particles have lower mechanical properties to cause particle damage during the mixing process (homogeneous mixing, high-pressure emulsifier, or the like).

[The problem to be solved by the invention]

The technical problem to be solved by the present disclosure is to provide a cosmetic composition containing fine particles, which has improved sebum absorption capacity and high durability, and can be stably dispersed in a water-in-oil or water-in-silicon cosmetic composition. [Technical means used to solve the problem]

In a general aspect, a cosmetic composition for improving the sebum control ability of sunscreens is provided, which comprises bowl-shaped non-porous particles, and these bowl-shaped non-porous particles include bis-ethylhexyloxyphenol methoxyphenyl The polymer matrix in which the triazine is dispersed. [Effect of Invention]

According to the embodiments of the present disclosure, the cosmetic composition according to the present disclosure includes bis-ethylhexyloxyphenol methoxyphenyl triazine in the form of bowl-shaped particles, and therefore, a cosmetic composition with high sebum absorption capacity can be provided Things. The micro particles stably disperse bis-ethylhexyloxyphenol methoxyphenyl triazine in the water-in-oil or water-in-silicon cosmetic composition. Through the sebum control ability, it will provide freshness after a long time after being applied to the skin. Feeling of use. In addition, the microparticles rely on sebum to absorb, causing minimal greasy feeling and stickiness after being applied to the skin, and thus can prevent the adsorption of fine dust on the skin.

Exemplary embodiments will now be described more fully below with reference to the accompanying drawings. However, the present disclosure can be embodied in many different forms, and should not be construed as being limited to the exemplary embodiments set forth herein. It will be obvious that these exemplary embodiments are provided so that the content of this disclosure will be complete and easy to understand by those skilled in the art. In addition, it will be obvious to those familiar with the technology that various changes and modifications can be made without departing from the spirit and scope of the disclosure as defined in the scope of the following patent applications.

In one aspect, a cosmetic composition for improving the sebum control ability of sunscreens is provided. The composition may include bowl-shaped non-porous microparticles, which include a polymer matrix in which bis-ethylhexyloxyphenol methoxyphenyltriazine is dispersed as an active ingredient. In this context, bis-ethylhexyloxyphenol methoxyphenyl triazine is not cross-linked into the polymer matrix, especially the polymerized cross-linked structure, but is homogeneously dispersed in the form of near-molecular units.

In another aspect, a bowl-shaped non-porous microparticle containing a polymer matrix in which bis-ethylhexyloxyphenol methoxyphenyl triazine is dispersed is provided for preparing a composition for improving the sebum control ability of sunscreens The purpose. In another aspect, a method for improving the sebum control ability of sunscreens is provided, which comprises the following steps: an effective amount of a polymer matrix containing bis-ethylhexyloxyphenol methoxyphenyltriazine dispersed therein The bowl-shaped non-porous particles are applied to the body in need. In yet another aspect, a bowl-shaped non-porous microparticle is provided, which contains a polymer matrix in which bis-ethylhexyloxyphenol methoxyphenyl triazine is dispersed, as used for improving the sebum control ability of sunscreens. The active ingredient used in the composition. In another aspect, a bowl-shaped non-porous microparticle is provided, which contains a polymer matrix in which bis-ethylhexyloxyphenol methoxyphenyl triazine is dispersed, for use in the improvement of the sebum control ability of sunscreens . In another aspect, a non-therapeutic use of bowl-shaped non-porous particles is provided. The bowl-shaped non-porous particles comprise a polymer matrix in which bis-ethylhexyloxyphenol methoxyphenyl triazine is dispersed as a modified Active ingredient for the sebum control ability of sunscreens.

Another chemical name for bis-ethylhexyloxyphenol methoxyphenyl triazine is 2,4-bis[4-(2-ethylhexyloxy)-2-hydroxyphenyl]-6-(4- Methoxyphenyl)-1,3,5-triazine, also known as Bemotrininol, has the CAS number 187393-00-6. For example, bis-ethylhexyloxyphenol methoxyphenyl triazine is available as Tinosorb S ^® from BASF. Although bis-ethylhexyloxyphenol methoxyphenyl triazine is known as an organic sunscreen that protects both UVA and UVB, it has poor solubility in solvents, and the disadvantage is that it needs to be dissolved in Highly polar oils (such as alkyl benzoate), etc., are applied to the oil phase. This oil usually exhibits an unbearable feeling of use and is greasy. In addition, bis-ethylhexyloxyphenol methoxyphenyl triazine has extremely low solubility for silicone-based oils. Therefore, when bis-ethylhexyloxyphenol methoxyphenyl triazine is applied to a formulation having silicone as an outer phase, it can be incorporated in only a small amount due to the problem of precipitation. Therefore, there is a problem that it is impossible to obtain sufficient sun protection effect.

Under these circumstances, the inventor of the present disclosure has conducted intensive research to prepare bis-ethylhexyloxyphenol methoxyphenyl triazine in the form of bowl-shaped microparticles, so that it can be stably dispersed in non-polar In the formulation of oil. As a result, we have found that these fine particles exhibit excellent sebum absorption capacity, and when they are applied to the skin, they absorb sebum secreted from the skin, and thus can effectively control the sebum remaining on the skin surface. The content of this disclosure is based on this discovery.

As used herein, the term "bowl shape" encompasses any concave bowl or container shape (regardless of inner concavity), or outer bowl shape. For example, the bowl shape may be a round concave bowl shape, more specifically, a hemispherical concave bowl shape. As the ratio of the internal concave volume increases, the bowl-like shape of the particles can provide higher sebum absorption. For example, these microparticles may have a sebum absorbency of 0.5 mL/g to 1 mL/g. These fine particles may have a sebum infiltration amount of 1.0 mL/g to 1.5 mL/g. As used herein, the term "non-porous" refers to particles having no pores or pores therein, and such particles may have a surface porosity of zero or approximately zero. According to the present disclosure, compared with spherical non-porous particles, the use of bowl-shaped non-porous particles can provide improved sebum absorption by virtue of the internal concave space. Therefore, when the bowl-shaped non-porous particles are applied to the skin, they can absorb or absorb sebum present on the skin to provide a matte and refreshing feeling of use. Therefore, by controlling sebum, the cosmetic composition applied to the skin can be retained for a long time, and the adsorption of fine dust in the air can be prevented. According to an embodiment of the present disclosure, the bowl-shaped microparticles are non-porous, and therefore, have higher particle durability compared with the conventional porous microparticles, and can stably disperse the almost insoluble bis-ethyl in the formulation Hexoxyphenol methoxyphenyl triazine. More specifically, as compared with spherical particles, the bowl-shaped non-porous particles according to an embodiment of the present disclosure have higher sebum absorption and, as compared with porous particles, lower sebum absorption. Therefore, the bowl-shaped non-porous particles can absorb a sufficient amount of sebum on the skin, while preventing the skin from drying out, and can provide a matte feeling of use.

According to an embodiment of the present disclosure, the microparticles may have an average diameter of 1 μm to 10 μm, but it is not limited to this, as long as they can be stably dispersed in the composition formulation and contain a high content of bis-ethyl Hexoxyphenol methoxyphenyl triazine. The average diameter of the microparticles is the average value of the particles contained in the composition, and is determined by hydrodynamic volume, and the limiting condition is that the particles are spherical. Specifically, 30 mL isotone (Beckman Coulter) was introduced into a 100 mL container, and a small amount of microparticles and a dispersant solution (10% Triton X-100) were added to the container. Next, the resulting solution was dispersed by a 150 W ultrasonic oscillator, and particle size analysis was performed by using Multisizer 4 (Beckman Coulter). Display the analysis result as a median value (d ₅₀ 3.5 μm to 5.5 μm), accurate to one-tenth of a unit. More specifically, these fine particles may have 1 μm or more, 2 μm or more, 3 μm or more, 4 μm or more, 5 μm or more, 6 μm or more, 7 μm or more. Large, 8 μm or more, 9 μm or more, or 9.9 μm or more, and 10 μm or less, 9 μm or less, 8 μm or less, 7 μm or less, 6 μm or more The average diameter is small, 5 μm or less, 4 μm or less, 3 μm or less, 2 μm or less, or 1.1 μm or less. Specifically, these fine particles may have an average diameter of 1 μm to 8 μm, and more specifically, 2 μm to 6 μm.

According to an embodiment of the present disclosure, bis-ethylhexyloxyphenol methoxyphenyl triazine is not cross-linked into the polymerized cross-linked structure of the polymer matrix, but is homogeneously dispersed in the cross-linked structure in the form of near-molecular units. In the formed network structure. Specifically, the polymerized cross-linking structure may include bis-ethylhexyloxyphenol methoxyphenyl triazine, and the polymerization product of a polymerizable monomer and a multifunctional cross-linking agent. More specifically, the microparticles can be prepared by dispersion polymerization using all of the oil phase including bis-ethylhexyloxyphenol methoxyphenyltriazine, polymerizable monomers, and multifunctional crosslinking agents.

According to an embodiment of the present disclosure, particles with different shapes can be obtained depending on the ratio of bis-ethylhexyloxyphenol methoxyphenyltriazine contained therein. In this context, the bowl-shaped microparticles according to an embodiment of the present disclosure may include bis-ethylhexyloxyphenol methoxyphenyltriazine in an amount of 20% to 30% by weight based on the total weight of the microparticles. More specifically, the bowl-shaped microparticles may contain 20% by weight or more, 21% by weight or more, 22% by weight or more, 23% by weight or more, 24% by weight or more based on the total weight of the microparticles. , 25% by weight or more, 26% by weight or more, 27% by weight or more, 28% by weight or more, 29% by weight or more, or 29.9% by weight or more, and 30% by weight or more Small, 29% by weight or less, 28% by weight or less, 27% by weight or less, 26% by weight or less, 25% by weight or less, 24% by weight or less, 23% by weight or less , 22% by weight or less, 21% by weight or less, or 20.1% by weight or less of bis-ethylhexyloxyphenol methoxyphenyltriazine.

According to an embodiment of the present disclosure, the polymerizable monomer can be any radical polymerizable monomer without specific limitations, as long as it can be copolymerized with a multifunctional crosslinking monomer. Specifically, the polymerizable monomer may be a radical polymerizable monomer containing a vinyl group. For example, the polymerizable monomer may include at least one radical polymerizable monomer selected from the group consisting of: styrene, methylstyrene, ethylstyrene, fluorostyrene, chlorobenzene At least one aromatic vinyl monomer in the group consisting of ethylene and vinyl toluene; and selected from methyl (meth)acrylate, ethyl (meth)acrylate, butyl (meth)acrylate, octyl At least one acrylic vinyl monomer in the group consisting of methyl (meth)acrylate, stearyl (meth)acrylate, benzyl (meth)acrylate, and glycidyl (meth)acrylate. According to an embodiment of the present disclosure, the multifunctional crosslinking agent can be any monomer capable of crosslinking polymerizable monomers, and there is no specific limitation. Specifically, the crosslinking agent may be a crosslinking agent containing two or more vinyl groups. For example, the crosslinking agent may include at least one crosslinking agent selected from the group consisting of: divinylbenzene, ethylene glycol dimethacrylate, diethylene glycol dimethacrylate, triethylene glycol dimethacrylate, Ethylene glycol dimethacrylate, trimethylpropane trimethacrylate, 1,3-butanediol dimethacrylate, 1,6-hexanediol dimethacrylate and tris(meth) Acrylate.

According to an embodiment of the present disclosure, the polymerization product may be a methacrylate cross-linked polymer formed by free radical polymerization between methacrylate and ethylene glycol dimethacrylate, and Can have a random network structure.

The weight ratio of the polymerizable monomer to the multifunctional crosslinking agent can vary depending on the desired degree of crosslinking, and is not particularly limited. For example, the multifunctional crosslinking agent can be based on 100% by weight of the polymerizable monomer from 0.1% to 100% by weight, specifically from 1% to 50% by weight, and more specifically from 1% to 25% by weight. % Blended.

According to an embodiment of the present disclosure, the composition may contain any amount of fine particles depending on the purpose of use without specific restrictions. Focusing on effective control of sebum, the composition may contain fine particles in an amount of 1% to 50% by weight based on the total weight of the composition, specifically, 1% by weight or more, 2% by weight or more, and 3% by weight % Or greater, 4% by weight or greater, 5% by weight or greater, 6% by weight or greater, 7% by weight or greater, 8% by weight or greater, 9% by weight or greater, 10% by weight Or greater, 11% by weight or greater, 12% by weight or greater, 13% by weight or greater, 14% by weight or greater, 15% by weight or greater, 16% by weight or greater, 17% by weight or Greater, 18% by weight or greater, 19% by weight or greater, 20% by weight or greater, 21% by weight or greater, 22% by weight or greater, 23% by weight or greater, 24% by weight or greater Large, 25% by weight or greater, 26% by weight or greater, 27% by weight or greater, 28% by weight or greater, 29% by weight or greater, 30% by weight or greater, 31% by weight or greater , 32% by weight or greater, 33% by weight or greater, 34% by weight or greater, 35% by weight or greater, 36% by weight or greater, 37% by weight or greater, 38% by weight or greater, 39% by weight or greater, 40% by weight or greater, 41% by weight or greater, 42% by weight or greater, 43% by weight or greater, 44% by weight or greater, 45% by weight or greater, 46 % By weight or greater, 47% by weight or greater, 48% by weight or greater, 49% by weight or greater, or 49.9% by weight or greater, and 50% by weight or less, 49% by weight or less, 48% by weight or less, 47% by weight or less, 46% by weight or less, 45% by weight or less, 44% by weight or less, 43% by weight or less, 42% by weight or less, 41 % By weight or less, 40% by weight or less, 39% by weight or less, 38% by weight or less, 37% by weight or less, 36% by weight or less, 35% by weight or less, 34% by weight % Or less, 33% by weight or less, 32% by weight or less, 31% by weight or less, 30% by weight or less, 29% by weight or less, 28% by weight or less, 27% by weight Or less, 26% by weight or less, 25% by weight or less, 24% by weight or less, 23% by weight or less, 22% by weight or less, 21% by weight or less, 20% by weight or Less, 19% by weight or less, 18% by weight or less, 17% by weight or less, 16% by weight or less, 15% by weight or less, 14% by weight or less, 13% by weight or less Small, 12% by weight or less, 11% by weight or less, 10% by weight or less, 9% by weight or less, 8% by weight or less, 7% by weight or less, 6% by weight or less , 5% by weight or less, 4% by weight or less, 3% by weight or less, or 2% by weight or less.

According to an embodiment of the present disclosure, the composition may be a water-in-oil (W/O) type composition. More specifically, the composition may be a water-in-silica (W/S) type composition. As used herein, the term "W/S type" means an emulsion comprising oil (essentially comprising silicone oil as a continuous phase) and an aqueous dispersed phase therein. In other words, the W/S type cosmetic composition means an emulsion in a state where an aqueous inner water phase is dispersed in an outer oil phase containing silicone oil. According to the present disclosure, compared with the related technology of stabilized fine particles by using bis-ethylhexyloxyphenol methoxyphenyl triazine, bis-ethylhexyloxyphenol methoxybenzene can be reduced in a higher content. The triazine is applied to the external phase of the W/O type or W/S type composition.

The W/S type cosmetic composition according to an embodiment of the present disclosure may include a polarity having at least one polar functional group selected from the following in an amount of 0% to 1% by weight based on the total weight of the composition Oil: carboxyl (COO), ketone (CO) and hydroxyl (OH). For example, the polar oil may include cetyl ethyl hexanoate, octyldodecanol myristate, di-C12-13 alkyl maleate, pentaerythritol tetraisostearate, pentaerythritol Tetraethylhexanoate, diisostearyl maleate, isopropyl palmitate, C12-C15 alkyl benzoate, dioctyl carbonate, dioctyl ether and 2-octyldecanoate Dialkyl alcohol.

The W/S type composition according to an embodiment of the present invention may include at least one silicone-based oil selected from the following: dimethylsiloxane, cyclomethicone, phenyltrimethicone Oxyane, polydimethylsiloxane, methyl phenyl polysiloxane, methyl phenyl polysiloxane, cyclomethicone, octamethyl cyclotetrasiloxane, decamethyl ring Pentasiloxane, dodecamethylcyclohexasiloxane, tetradecamethylhexasiloxane and octamethyltrisiloxane. According to an embodiment of the present disclosure, the composition may include 15% to 60% by weight, specifically 15% to 50% by weight, and more specifically 20% to 40% by weight based on the total weight of the composition The amount of silicone-based oil. According to an embodiment of the present disclosure, the composition may remain water. In the W/S type cosmetic composition according to an embodiment of the present disclosure, the composition may further include a silicone-based surfactant, which includes polyethylene glycol (PEG), polypropylene glycol (PPG) and polyglycerin At least one of the groups. Specifically, focus on the stable dispersion of microparticles containing bis-ethylhexyloxyphenol methoxyphenyltriazine and prevent the deposition of bis-ethylhexyloxyphenol methoxyphenyltriazine in the form of crystals on the interface The composition according to an embodiment of the present disclosure may use a silicone-based surfactant with PEG added. Specific examples of PEG-added silicone-based interface active agents may include PEG/PPG-18/18 dimethylsiloxane (cyclopentasiloxane and PEG/PPG-18/18 dimethylsiloxane) , PEG-30 dipolyhydroxystearate, PEG-7 dimethylsiloxane, PEG-10 dimethylsiloxane, cyclopentasiloxane/PEG.PPG-19.19 dimethylsiloxane, Sorbitol Isostearate, Lauryl PEG.PPG-18.18 Methylsiloxane, Cetyl PEG.PPG-10.1 Dimethicone, Lauryl PEG-9 Polydimethylsiloxane Dimethylsiloxane or similar. In addition, the composition according to an embodiment of the present disclosure may use at least one of the above-mentioned silicone-based interface active agents added with PEG, but is not limited thereto. More specifically, the silicone-based interfacial active agent added with PEG may be a non-ionic interfacial active agent having a hydrophile-lipophile balance (HLB) of 1 to 6. For example, the surfactant may be included in an amount of 0.01% to 10% by weight, specifically 1% to 8% by weight, and more specifically 3% to 6% by weight based on the total weight of the composition. When the surfactant is contained in an amount of less than 0.01% by weight, the dispersibility of the microparticles may be degraded. When the surfactant is contained in an amount greater than 10% by weight, the viscosity can be reduced and the refreshing feeling of use can be reduced.

The cosmetic composition according to an embodiment of the present disclosure can be formulated with a medium or substrate that is acceptable for cosmetics or dermatology. This covering is suitable for any formulations for topical application, and can be used in solutions, gels, solids, anhydrous massage products, emulsions (by in the aqueous phase, suspensions, microemulsions, microcapsules, particles or ions (liposomes) and It is provided in the form of dispersing the oil phase in the ionic fragrance powder dispersion agent), or as a cream, epidermis, lotion, powder, ointment, spray or concealer stick. In addition, the cosmetic composition can be used in the form of a foam or aerosol composition (further containing a compressed propellant). These formulations can be obtained by methods generally known to those skilled in the art.

According to an embodiment of the present disclosure, the composition may be a sunscreen product. The sun protection factor (SPF) of the composition can be 10 to 50 or greater, as calculated according to the following formula 1. The protection level (PA) of UVA can be from PA+ to PA++++.

[Formula 1] Sun protection factor = (minimum erythema dose at the skin site where the cosmetic composition is applied)/(minimum erythema dose at the skin site where no cosmetic composition is applied)

According to an embodiment of the present disclosure, depending on the application, the composition may further include an organic sunscreen agent or an inorganic sunscreen agent. Each of the organic sunscreen agent or the inorganic sunscreen agent may be included in an amount of 0.01% to 20% by weight based on the total weight of the composition, but is not limited thereto. In particular, organic sunscreens may include octyl methoxycinnamate, octyl salicylate, octocrylene, butylmethoxybenzophenone, oxybenzone, octyltriazinone, anthracene Methyl quinoneate, 3,4-methylbenzylidene camphor, isoamyl p-methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, methylene bisbenzotriazole tetramethyl Butyl phenol or the like. In addition, the inorganic sunscreen agent may include powders of titanium dioxide, zinc oxide, iron oxide, or the like.

According to an embodiment of the present disclosure, the composition may be a cosmetic product. Specifically, the composition can be formulated into makeup base, liquid foundation, BB cream, CC cream, concealer, makeup primer, or the like, but it is not limited thereto. When the composition is applied to the skin, relying on the bowl-like shape of the microparticles, it exhibits an excellent wearing feeling to the skin. In addition, since the composition has a matte and refreshing feeling of use due to its excellent wearing feeling and sebum control ability, it can significantly reduce the adhesion of fine dust to the skin compared with conventional cosmetic compositions. In this context, the composition according to an embodiment of the present disclosure can be used to prevent adhesion of fine dust.

According to an embodiment of the present disclosure, the cosmetic composition may include active ingredients together with other ingredients, and the limitation is that the other ingredients will not adversely affect the main effect, or may provide a synergistic effect with the main effect. Depending on the formulation of the cosmetic composition or the purpose of use, ingredients other than the active ingredients according to the present disclosure can be selected and combined by those familiar with the art. In addition to the above-mentioned ingredients, if necessary, the cosmetic composition according to an embodiment of the present disclosure may further include other ingredients currently used in the cosmetic composition. For example, these ingredients include moisturizers, emollients, thickeners, organic and inorganic pigments, organic powders, preservatives, fungicides, antioxidants, plant extracts, pH modifiers, alcohol, colorants , Perfume, blood flow stimulant, cooling agent, antiperspirant, pure water or the like. The ingredients that can be incorporated into the cosmetic composition according to the present disclosure are not limited to the ingredients described above. In addition, these ingredients can be used without compromising the goals and effects of the content of this disclosure. (Example)

Hereinafter, the content of the disclosure will be explained in more detail with reference to examples, comparative examples and test examples. The following examples and experiments are for illustrative purposes only. In addition, it will be obvious to those familiar with the technology that the scope of the disclosure is not limited to the following examples, comparative examples, and test examples. [Example 1]

9 g of polyvinyl alcohol was introduced into the reaction vessel and dissolved in 2000 g of distilled water to prepare an aqueous phase. Next, 200 g of methyl methacrylate (MMA) and 25 g of ethylene glycol dimethacrylate were introduced into the emulsifier and stirred therein for 5 minutes, and then 75 g of bis-ethylhexoxyphenol methyl Oxyphenyltriazine (BEMT) was further introduced thereto and dissolved for 30 minutes to prepare an oil phase. Next, 3 g of 2,2'-azobis-(2,4-dimethylvaleronitrile) was introduced as an initiator, and mixed there. After that, the water phase was introduced to the emulsifier, and dispersion polymerization was performed by using this emulsifier for 30 minutes, and then the mixture was warmed to react at 50° C., and the reaction was performed for 15 hours. The resulting polydisperse microparticles were dehydrated by using a reduced pressure filter and washed with water three times, followed by vacuum drying. In this way, bowl-shaped particles containing 25% by weight of bis-ethylhexyloxyphenol methoxyphenyltriazine (yield rate = 90%, average particle diameter = 2 μm) were obtained.

Figures 1A to 1F show the scanning electron microscopic (SEM) images (Figures 1A and 1B) of the bowl-shaped particles obtained, together with the SEM images of the comparative example, that is, porous PMMA spherical particles (comparison Example 1, Figure 1C and Figure 1D) and non-porous PMMA spherical particles (Comparative Example 2, Figure 1E and Figure 1F). Each of the images on the right (Figure 1B, Figure 1D, Figure 1F) is an image taken at a higher magnification as compared with the corresponding left image (Figure 1A, Figure 1C, Figure 1E) , And the same sample is shown. As can be seen from FIG. 1A and FIG. 1B, the microparticles according to an embodiment of the present disclosure have a characteristic round bowl-shaped structure. It is believed that this shape is formed from the high degree of cross-linking and homogeneous integration of the polymer matrix configured to stably incorporate therein a high content of bis-ethylhexoxyphenol methoxyphenyl triazine particles in the polymer matrix. The concentration of bis-ethylhexyloxyphenol methoxyphenyl triazine in the substance matrix is produced.

In addition, the obtained bowl-shaped particles were used to determine oil absorption and total immersion. According to 0JIS K 5101-13-1, the oil absorption is judged as a test method for the oil absorption of the substrate in a room controlled at room temperature (23°C), and by using a porosity meter (Autopore IV 9500, micrometrics, Londonderry, NH, USA) to determine the total immersion. The results of oil absorption are correlated with the results of total immersion. As can be seen from the results in Table 1 below, the microparticles according to one embodiment of the present disclosure have an oil absorbency of 0.888 mL/g and a total immersion amount of 1.37 mL/g. The result corresponds to an oil absorption that is at least 150% higher than that of the non-porous PMMA spherical particles, and corresponds to a total immersion that is at least 210% higher than that of the non-porous PMMA spherical particles. In addition, the result corresponds to an oil absorption of about 56% of the oil absorption of the porous PMMA spherical particles, and corresponds to a total immersion of about 0.87 times the total immersion of the porous PMMA spherical particles. This is derived from the bowl-shaped shape and non-porous characteristics of the particles according to an embodiment of the present disclosure. [Table 1] Oil absorption (mL/g) Total immersion (mL/g) Example 1 (bowl-shaped non-porous particles) 0.888 1.37 Comparative Example 1 (Porous spherical PMMA particles) 1.60 1.57 Comparative Example 2 (Non-porous spherical PMMA particles) 0.573 0.65 [Test Case 1]

In order to analyze the composition containing bowl-shaped microparticles according to an embodiment of the present disclosure in terms of the feeling of use, the following test was performed compared with a comparative example using different types of powders corresponding to the microparticles.

First, the oil phase ingredients are mixed by using the composition shown in Table 2, followed by homogeneous dispersion and dissolution. The water phase ingredients are dissolved at a temperature of 40°C to 50°C, and introduced into the oil phase ingredients by using a homogenizer to obtain each of the W/S-type cosmetic compositions. [Table 2] ingredient Example 2 Comparative Example 3 (Carrier) Comparative Example 4 (CR50) Comparative Example 5 (Art-pearl) Oil phase Ethylhexyl methoxycinnamate 5 5 5 5 Ethylhexyl salicylate 3 3 3 3 Dimethylsiloxane 20 20 20 20 Cyclopentasiloxane*Cyclohexasiloxane 10 10 10 10 C12-15 Alkyl Benzoate*C12-15 Ethanol 6 6 6 6 Distearyl dimethylamine hectorite 0.3 0.3 0.3 0.3 PEG-10 Dimethylsiloxane 1.5 1.5 1.5 1.5 Tocopherol*Lauryl PEG-9 Polydimethylsiloxane Ethyl Dimethicone 1.5 1.5 1.5 1.5 Example 1 8 - - - Comparative example 2 - - - 8 Titanium Dioxide (CI 77891)*Aluminum Hydroxide*Triethoxyoctylsilane 8 water box Distilled water Up to 100 Up to 100 Up to 100 Up to 100 Polyol 5 5 5 5 Sodium chloride 1 1 1 1 2Na EDTA 0.05 0.05 0.05 0.05 preservative 1.15 1.15 1.15 1.15 Total (weight%) 100 100 100 100

Example 2 is a formulation containing the fine particle powder according to Example 1, Comparative Example 3 is a carrier formulation that does not contain powder, and Comparative Example 4 is a raw material containing a _{TiO 2 colorant that can be obtained as OTS-2 TiO 2} CR-50 The formulation of Comparative Example 5 is a formulation containing Comparative Example 2 (non-porous spherical PMMA particles).

Next, allow 10 culture panels (AP R&D skin care culture panels) in the Amore Pacific research laboratory to use each of the formulations according to Example 2 and Comparative Examples 2 to 4, and evaluate the feeling of use according to the following scheme. -Evaluate the quality after application and absorption, while allowing the test product to be absorbed into the skin by rolling for 2 minutes. -Repeat the evaluation twice for the same test product. 1) Apply the same lotion to the forearm in a predetermined amount, and then allow to stop for 3 minutes for absorption. 2) After absorption, use the same foam cleaner to clean the forearm. 3) Mark the application area on the arm before cleaning is completed by using a round stamp with a diameter of 5 cm. 4) Provide the test product in the marked circle in the amount of 50 μL. 5) Use the index finger to scroll twice within 10 seconds (twice/sec). 6) After rolling, determine the absorption rate (degree), and pat the skin with your index finger and middle finger at the same time. 7) After the absorption is complete, allow the test site to stop until the alarm sounds for 2 minutes. 8) After 2 minutes, evaluate the quality after absorption.

The test items include 10 items (coolness, spreadability, smoothness, greasy feel, greasy feel, watery feel, heaviness, stickiness, stickiness) corresponding to the feeling of use after application of each composition And absorption rate) and 7 items corresponding to the feeling of use after absorption (gloss, greasy feeling after absorption, moisturizing feeling, stickiness after absorption, softness, smoothness and residual feeling).

As a result, as shown in Figure 2, the test product generally exhibits a similar spreadability trend, but depending on the powder type, there is a very small difference. In the case of Comparative Example 4 (CR50), due to its unique stickiness and spreadability and heavy use feel, it exhibits heavy spreadability and, in particular, tends to be difficult to absorb. This is due to the fact that the formulation does not It is absorbed but remains on the skin.

As shown in Figure 3, Example 2 and Comparative Example 5 (Art-pearl) show similar trends after absorption, but depending on the powder type, there is a difference in sense of completion. In the case of Comparative Example 3 (vehicle), it exhibited a strong greasy feel after absorption, and was evaluated to provide a feeling of use that left high gloss and residue. In the case of Example 2, it exhibited a trend of finishing feeling similar to that of Comparative Example 5 (Art-pearl), and provided lower gloss and oily feeling after absorption. In the case of Comparative Example 5 (Art-pearl), the evaluation is as soft and smoother as that of Example 2 (depending on the feeling derived from the powder particles), but it is shown after absorption as compared with Example 2 High oiliness and luster.

Figures 4 and 5 show detailed evaluation results of Example 2 and Comparative Example 3 (vehicle) in terms of feeling of use. As shown in Figure 5, Example 2 shows a softer feel after absorption as compared to Comparative Example 3 (vehicle), and provides a significantly reduced oily feel, residual feel and stickiness after absorption. It is believed that the bowl-shaped microparticles according to Example 2 absorb skin sebum to provide a more refreshing feeling of use. [Test Case 2]

The following clinical tests were performed to evaluate the fine dust protection ability of the bowl-shaped microparticle-containing composition (Example 2, product name: 30880008) according to an embodiment of the present disclosure.

The following description is a self-research report (PNK-18N15-BR1R2) "For 30880008 (CSR-B1W-43396) skin tone, recognized whitening index (VB), homogeneity, skin texture coverage, water loss, and substitute fine dust protection The test results extracted from the Human Smear Test of Ability. This report was requested by Amore Pacific from the Skin Clinical Research Center and received on December 26, 2018.

Test product Product name: 30880008, material reference number: 18N15-BR1-S2

Using the test products in that the forearm of the test body of the defined test product application site and the artificial sebum application area (width × length = 1.5 × 4 cm), press 1 μL / quantity cm ² of the test products and the artificial sebum smear to define Of the site.

Number of times the test product is used once

Choice of test subject Women aged 25 to 35 meet the selection criteria and do not correspond to the exclusion criteria. -Selection criteria 1. Accept the person who will be notified by the test manager who fully explains the project, or accept the person who is trusted by the test manager and writes and signs in the consent form. 2. There are no healthy persons with acute or chronic physical diseases including skin diseases. 3. Personnel who are allowed to follow up during the test. -Exclusion criteria 1. People suffering from mental illness. 2. People with infectious skin diseases. 3. Those who received immunosuppressive drug treatment within 3 months before the start of the test. 4. Those who received systemic steroids or light therapy within one month before the start of the test. 5. Those who have wounds at the test site that make it difficult to test. 6. People with allergic skin. 7. Persons who are significantly sensitive or allergic to cosmetics, drugs or daily light exposure. 8. Persons who received skin exfoliation or skin care within 3 months before the start of the test. 9. Pregnant or breastfeeding women. 10. Other personnel judged by the test manager or the person in charge of the test as unsuitable for the human smear test.

testing method For helpful evaluation, allow the test subject to rest for 30 minutes in a room at a temperature of 20°C to 25°C and a humidity of 40% to 60% in a constant temperature/constant humidity condition, so that the skin surface temperature and humidity can be adapted The environment of the test space. During rest, limit the water intake of the test subject. In order to make an objective judgment, a researcher conducts the test and tests the same part each time.

Before using the test product, after using the test product and after applying the substitute fine dust, determine the substitute fine dust protection ability.

In order to determine the fine dust protection effect of the substitute, define the test product application site and artificial sebum application site (width x length 1.5 x 4 cm) on the arm of the test subject, and then apply the test product and artificial sebum to them. Then, transfer the front arm part of the main body to the sealed space in the sprayer, and spray sufficient amount (about 1.5 g) of the substitute fine dust (carbon powder) containing carbon as the main component of the substitute fine dust in all directions To cause adsorption. Before using the test product, after using the test product, and after spraying the substitute fine dust, use Visia-CR to take pictures of the forearm. The photographed images are ^{analyzed by mage-pro ®} plus, and a specific area is marked in these images for evaluation based on the difference in brightness (intensity) in the area. As the area approaches black, the brightness (intensity) decreases. Each brightness (intensity) value is corrected by subtracting it from the maximum value 255 of the color gamut (0 to 255).

The result of the judgment of the fine dust protection ability of the substitute After using the test product, determine the change in the fine dust protection ability of the test product substitute. -Test product: Compared with the test product, after spraying the substitute fine dust, there is a significant increase of 29.377% (p <0.05). -Artificial sebum: If compared with the test product, after spraying the substitute fine dust, there is a significant increase of 32.436% (p <0.05). -Comparison between groups: If compared with artificial sebum, based on the results after using the test product, after spraying the fine dust substitute, the test product showed a significant difference (p <0.05) (see Figure 6 to Figure 8).

in conclusion Therefore, it is judged that the "3088008" product is a product that helps to improve the fine dust protection ability of substitutes in one-time use.

According to the present disclosure, the following embodiments can be provided.

According to the first embodiment, a bowl-shaped non-porous microparticle containing a polymer matrix in which bis-ethylhexyloxyphenol methoxyphenyl triazine is dispersed is provided for preparing a composition for improving the sebum control ability of sunscreens use.

According to the second embodiment, there is provided the use as defined in the first embodiment, which contains bis-ethylhexyloxyphenol methoxyphenyltriazine in an amount of 20% to 30% by weight based on the total weight of the microparticles.

According to the third embodiment, there is provided the use as defined in the first or second embodiment, wherein the average diameter of these fine particles is 1 μm to 10 μm.

According to the fourth embodiment, the use as defined in any one of the first to third embodiments is provided, wherein the sebum absorbability of these microparticles is 0.5 mL/g to 1 mL/g.

According to the fifth embodiment, the use as defined in any one of the first to fourth embodiments is provided, wherein the sebum infiltration amount of these fine particles is 1.0 mL/g to 1.5 mL/g.

According to a sixth embodiment, there is provided the use as defined in any one of the first to fifth embodiments, wherein the polymer matrix comprises bis-ethylhexyloxyphenol methoxyphenyl triazine, and polymerizable monomers and poly Polymerization product of functional crosslinking agent.

According to a seventh embodiment, there is provided the use as defined in any one of the first to sixth embodiments, wherein the polymerizable monomer includes at least one selected from the group consisting of: styrene, At least one aromatic vinyl monomer in the group consisting of methyl styrene, ethyl styrene, fluorostyrene, chlorostyrene and vinyl toluene; and selected from methyl (meth) acrylate, ethyl ( Meth) acrylate, butyl (meth) acrylate, octyl (meth) acrylate, stearyl (meth) acrylate, benzyl (meth) acrylate and glycidyl (meth) acrylate ) At least one acrylic vinyl monomer from the group consisting of acrylic esters.

According to an eighth embodiment, there is provided the use as defined in any one of the first to seventh embodiments, wherein the multifunctional crosslinking agent includes at least one selected from the group consisting of: divinylbenzene , Ethylene glycol dimethacrylate, diethylene glycol dimethacrylate, triethylene glycol dimethacrylate, trimethylpropane trimethacrylate, 1,3-butanediol dimethyl Acrylate, 1,6-hexanediol dimethacrylate and tri(meth)acrylate.

According to a ninth embodiment, there is provided the use as defined in any one of the first to eighth embodiments, wherein the composition includes fine particles in an amount of 1% to 50% by weight based on the total weight of the composition.

According to a tenth embodiment, there is provided the use as defined in any one of the first to ninth embodiments, wherein the composition is a water-in-oil (W/O) type composition.

According to an eleventh embodiment, there is provided the use as defined in any one of the first to tenth embodiments, wherein the composition is a cosmetic product.

According to the twelfth embodiment, there is provided the use as defined in any one of the first to eleventh embodiments, wherein the composition is used for preventing the adsorption of fine dust.

no

FIG. 1A is a photographic image of bowl-shaped particles according to an embodiment of the present invention.

Figure 1B is a photo of the bowl-shaped particles in Figure 1A taken under high magnification.

Figure 1C shows a photograph of a porous spherical polymethyl methacrylate (PMMA) as a comparative example of the present disclosure.

Figure 1D is a photo image of porous spherical PMMA particles in Figure 1C taken under high magnification.

Fig. 1E is a photograph showing a non-porous spherical PMMA particle as a comparative example of the present disclosure.

Figure 1F is a photo of the non-porous spherical PMMA particles in Figure 1E taken under high magnification.

Figure 2 shows the results of the evaluation of the feeling of use of the composition containing bowl-shaped particles and the composition containing different types of powders after being applied to the skin according to an embodiment of the present disclosure.

Figure 3 shows the results of the evaluation of the feeling of use of the composition containing bowl-shaped particles and the composition containing different types of powders after being applied and absorbed into the skin according to an embodiment of the present disclosure.

Figure 4 shows the results of a more detailed evaluation of the feeling of use of the composition containing bowl-shaped particles and the composition containing different types of powders after being applied to the skin according to an embodiment of the present disclosure.

Figure 5 shows the results of a more detailed evaluation of the feeling of use of a composition containing bowl-shaped particles and a composition containing different types of powders after being applied and absorbed into the skin according to an embodiment of the present disclosure.

FIG. 6 illustrates the result of determining the fine dust protection ability of a composition containing bowl-shaped particles according to an embodiment of the present disclosure.

FIG. 7 illustrates the result of judging the fine dust protection ability of a composition containing bowl-shaped particles according to an embodiment of the present disclosure as compared with before using the composition.

FIG. 8 illustrates the result of judging the fine dust protection ability of a composition containing bowl-shaped particles according to an embodiment of the present disclosure compared with the composition after using the composition.

Domestic deposit information (please note in the order of deposit institution, date and number) no Foreign hosting information (please note in the order of hosting country, institution, date, and number) no

Claims (12)

A bowl-shaped non-porous microparticle containing a polymer matrix in which bis-ethylhexyloxyphenol methoxyphenyl triazine is dispersed is used to prepare a composition for improving the sebum control ability of a sunscreen product. The use according to claim 1, wherein the bis-ethylhexyloxyphenol methoxyphenyl triazine is contained in an amount of 20% to 30% by weight based on the total weight of the fine particles. The use according to claim 1, wherein the average diameter of the fine particles is 1 μm to 10 μm. The use according to claim 1, wherein the sebum absorbability of the fine particles is 0.5 mL/g to 1 mL/g. The use according to claim 1, wherein the sebum soaking amount of the fine particles is 1.0 mL/g to 1.5 mL/g. The use according to claim 1, wherein the polymer matrix comprises bis-ethylhexyloxyphenol methoxyphenyltriazine, and a polymerization product of a polymerizable monomer and a multifunctional crosslinking agent. The use according to claim 6, wherein the polymerizable monomer comprises at least one selected from the group consisting of: styrene, methylstyrene, ethylstyrene, fluorostyrene, chlorine At least one aromatic vinyl monomer in the group consisting of styrene and vinyl toluene; and selected from methyl (meth)acrylate, ethyl (meth)acrylate, butyl (meth)acrylate, At least one acrylic vinyl monomer from the group consisting of octyl (meth)acrylate, stearyl (meth)acrylate, benzyl (meth)acrylate, and glycidyl (meth)acrylate . The use according to claim 6, wherein the multifunctional crosslinking agent comprises at least one selected from the group consisting of: divinylbenzene, ethylene glycol dimethacrylate, diethylene glycol dimethacrylate Methacrylate, triethylene glycol dimethacrylate, trimethylpropane trimethacrylate, 1,3-butanediol dimethacrylate, 1,6-hexanediol dimethacrylate And tri(meth)acrylate. The use according to claim 1, wherein the composition contains the fine particles in an amount of 1% to 50% by weight based on the total weight of the composition. The use according to claim 1, wherein the composition is a water-in-oil (W/O) type composition. The use according to claim 1, wherein the composition is a cosmetic product. The use according to claim 1, wherein the composition is used to prevent the adsorption of fine dust.

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