TW202007788A - Implant plasma coating and molecular cross-linking process and structure in which functional molecules are bonded with an cross-linking agent to remain on the surface of the dental implant - Google Patents

Abstract

The invention provides an implant plasma coating and molecular cross-linking process and structure. The implant plasma coating and molecular cross-linking process includes the steps of: providing a finished implant product; decomposing a monomer containing silicon-based molecules into an ionic state (plasma), and forming a coating on the surface of an implant; attaching a cross-linking agent capable of being covalently bonded with the siloxane coating on the surface of the implant; coating functional molecules on the outside of the cross-linking agent to produce chemical bonds so as to remain on the surface of the implant, thereby completing the implant plasma coating and molecular cross-linking structure.

Description

Implant plasma coating and molecular cross-linking process and structure

The invention relates to dental implants, in particular to a flow and structure of implant plasma coating and molecular cross-linking.

Generally, intraosseous implants such as artificial tooth roots (implants) will require a recovery period of several months after surgery to allow bones to re-grow and combine with the implant, or osseointegration. The efficiency of osseointegration is directly related to the stability of the implant. When the implant is shaken, osseointegration cannot be performed. Therefore, doctors usually make the size of the implant slightly larger than the size of the hole in the bone during surgery. To produce better initial stability.

Within two weeks after the dental implant surgery, the damaged bone will be decomposed and absorbed by the body, and the implant will loosen at this time.

However, when the implant is shaken due to force, it will prevent the growth of bone cells, which will lead to the failure of osseointegration. Because of this, the success rate of conventional dental implants is usually low.

In addition, the above problems may occur during the period of osseointegration. Since the implant does not have a vascular network like natural bone, the implant's ability to inhibit bacteria is poor, so it is easy to cause complications such as "peri-implant inflammation". If the patient is not sure about oral cleansing and then causes peri-implant inflammation, the dental implant failure rate is as high as 20-30%.

It can be seen from the above that when a patient undergoes dental implant surgery and implants are implanted, the implants will be immediately exposed to the harsh environment of the oral cavity, and they must bear the mechanical force of the patients chewing and the breeding of bacteria, which will greatly reduce the success rate of dental implants.

It can be seen that there are still many defects in the above-mentioned conventional dental implant method. It is not a good designer, and it needs to be improved urgently.

In view of the shortcomings derived from the above-mentioned conventional dental implant method, the inventor of the present case is eager to improve and innovate. After years of painstaking research, he finally successfully completed the process and structure of this implant plasma coating and molecular cross-linking.

The object of the present invention is to provide a process and structure for implant plasma coating and molecular cross-linking, which is to decompose monomer containing silicon-oxygen molecules into plasma state and then coat the coating on the surface of the implant, and then adhere to the surface of the implant The cross-linking agent then bonds the functional molecule with the cross-linking agent, so that the functional molecule remains on the surface of the implant, thereby improving the success rate of the dental implant surgery.

In order to achieve the above objective, the process of implant plasma coating and molecular cross-linking of the present invention includes the following steps: providing a finished implant; decomposing the monomer containing silicon-based molecules into an ionic state (plasma), and applying it to the plant A coating is formed on the surface of the body; a cross-linking agent that can be covalently bonded to the coating of the silicone is adhered or coated or soaked on the surface of the implant; a functional molecule is coated on the cross-linking agent to cause chemical bonding Retain on the surface of the implant to complete the process of implant plasma coating and molecular cross-linking.

In order to achieve the above object, the plasma coating of the implant and the molecular cross-linking structure of the present invention include: an implant for embedding in the alveolar bone and supporting a denture, which includes an artificial tooth root and is disposed on the artificial tooth root The base; monomers containing silicon-oxygen molecules are coated on the surface of the implant, the monomers containing silicon-oxygen molecules are decomposed into ionic state and then coated on the surface of the implant; crosslinking agent is attached or coated Or immersed in the surface of the implant after the coating, the cross-linking agent is a chemical cross-linking agent or a natural cross-linking agent or a combination thereof, for example: genipin or proanthocyanidins; functional molecules are coated on the cross-linking agent It also generates chemical bonds to keep the functional molecules on the surface of the implant. The functional molecules are bone growth promoting molecules or antibacterial molecules.

In order to further understand the features and technical content of the present invention, please refer to the following detailed description and drawings of the present invention. However, the accompanying drawings are provided for reference and explanation only, and are not intended to limit the present invention.

1‧‧‧Implant

11‧‧‧ Artificial tooth root

12‧‧‧Dock

2‧‧‧Monomer containing silica molecules

3‧‧‧Crosslinking agent

4‧‧‧ Functional Molecule

The first figure is a schematic diagram of the implementation process of the implantation mechanics blocking process of the present invention.

The second figure is a schematic structural view of the mechanical blocking structure of the dental implant of the present invention.

The third figure is a partially enlarged schematic view of the mechanical blocking structure of the dental implant of the present invention.

In order to make the above and other objects, features and advantages of the present invention more comprehensible, preferred embodiments are described below in conjunction with the accompanying drawings, which are described in detail below.

As shown in the first figure, the present invention provides an implant plasma coating and molecular cross-linking process, which includes the following steps: Step 1: 10: Provide a finished implant, and the implant includes an artificial tooth root and is provided in the The base on the artificial tooth root; Step 2: 20: Decompose the monomer containing siloxane molecules into an ionic state (plasma) and form a nano-coating on the surface of the implant; Step 3: 30: Attach to the surface of the implant Or coated or soaked cross-linking agent, the cross-linking agent is a chemical cross-linking agent or a natural cross-linking agent or a combination thereof, and is similar to molecular viscose, such as: genipin, proanthocyanidins, etc., when the cross-linking agent comes into contact with silica When coating the alkane, it will produce covalent bonding to make it have the ability to combine with other functional molecules; Step 4 40: coat functional molecules on the crosslinking agent to make it chemically bonded and remain on the surface of the implant The functional molecule is a bone growth promoting molecule, which is used to shorten the osseointegration time and shorten the course of treatment; or it can be an antibacterial molecule to reduce the incidence of peri-implantitis, thereby increasing the success rate of surgery; through the above steps Complete the process of implant plasma coating and molecular cross-linking.

Please refer to the second and third figures, the present invention provides an implant plasma coating and molecular cross-linking structure, which includes: an implant 1, which is used to embed in the alveolar bone and support a denture, which It includes an artificial tooth root 11 and a base 12 disposed on the artificial tooth root 11, wherein the artificial tooth root 11 is used to be embedded in the alveolar bone, and the base 12 is used to support the denture; a single piece containing silicon molecules Body 2, coated on the surface of the implant 1, the monomer 2 containing silicon-based molecules is decomposed into an ionic state and coated on the surface of the implant 1; the cross-linking agent 3 is attached or coated or soaked in the coating On the surface of the following implant 1, the crosslinking agent 3 is a chemical crosslinking agent or a natural crosslinking agent or a combination thereof, such as: genipin or proanthocyanidin; the functional molecule 4 is coated on the outside of the crosslinking agent 3 In addition, a chemical bond is generated so that the functional molecule 4 remains on the surface of the implant 1. The functional molecule 4 is a bone growth promoting molecule or an antibacterial molecule.

From the above structure, it can be seen that the present invention is to cross-link molecules on the implant 1 through the coating, according to different functional molecules 4 to provide the corresponding function of the implant 1, for example, the bone growth promoting molecule system is used to shorten the osseointegration time and shorten The course of treatment, and antibacterial molecules are used to reduce the incidence of peri-implant inflammation, thereby increasing the success rate of dental implant surgery.

The above detailed description is a specific description of a feasible embodiment of the present invention, but this embodiment is not intended to limit the patent scope of the present invention, and any equivalent implementation or change without departing from the technical spirit of the present invention should be included in The patent scope of this case. The scope of protection of the rights of the present invention shall be as described in the scope of patent application mentioned later.

Claims (11)

An implant plasma coating and molecular cross-linking process includes the following steps: providing a finished implant; decomposing the monomer containing silicon-based molecules into an ionic state (plasma), and forming a coating on the surface of the implant; The surface of the implant is attached or coated or soaked with a cross-linking agent that can form a covalent bond with the silicone coating; the functional molecules are coated on the cross-linking agent to make it chemically bonded and remain on the surface of the implant. The implant plasma coating and molecular cross-linking process as described in item 1 of the patent application scope, wherein the implant includes an artificial tooth root and a base provided on the artificial tooth root. The implant plasma coating and molecular cross-linking process as described in item 1 of the patent application scope, wherein the cross-linking agent is a chemical cross-linking agent or a natural cross-linking agent or a combination thereof, and is a molecular adhesive. The implant plasma coating and molecular cross-linking process as described in item 1 of the patent application scope, wherein the cross-linking agent is genipin or proanthocyanidins. The implant plasma plasma coating and molecular cross-linking process as described in item 1 of the patent scope, wherein the functional molecule is a bone growth promoting molecule, which is used to shorten the bone integration time. The implant plasma coating and molecular cross-linking process as described in item 1 of the patent application scope, wherein the functional molecule is an antibacterial molecule to reduce the incidence of inflammation around the implant. An implant plasma coating and molecular cross-linking structure, including: an implant for embedding in alveolar bone and supporting a denture, which includes an artificial tooth root and a base disposed on the artificial tooth root; contains silicon oxide Molecule-like monomers are coated on the surface of the implant; cross-linking agent is attached to the surface of the implant after the coating; functional molecules are attached or coated or soaked outside the cross-linking agent and produce chemical bonding So that the functional molecule remains on the surface of the implant. The mechanical blocking structure of dental implants as described in item 7 of the patent application scope, wherein the single system containing silicon-oxygen molecules is decomposed into an ion state and then coated on the surface of the implant. The dental implant mechanical blocking structure as described in item 7 of the patent application scope, wherein the crosslinking agent is a chemical crosslinking agent or a natural crosslinking agent or a combination thereof, and is a molecular adhesive. The dental implant mechanical blocking structure as described in item 7 of the patent application scope, wherein the functional molecule is a bone growth promoting molecule or an antibacterial molecule. The mechanical blocking structure of dental implants as described in item 7 of the patent application scope, wherein the crosslinking agent is genipin or proanthocyanidins.

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