TW201634042A - Skin cleansing composition - Google Patents

Abstract

An object of the present invention is to provide a skin cleansing composition which is powder or granular and comprises N-acylglutamic amino acid salt, and which is excellent in foaming speed and improved foam quality. The skin cleansing composition according to claim 1, is characterized by adding the mass ratio of the N-acylglutamic amino acid salt to the N-fatty acid acyl aminoethyl-N-2-hydroxyethyl glycine salt is 100:1 to 1:1.

Description

Skin cleansing composition

The present invention relates to a powdery or granulated skin cleansing composition.

Conventionally, the powdery skin cleansing material is prepared by mixing and pulverizing a detergent with an inorganic powder or an organic powder which is a builder, and when it is a granular skin cleansing material, The raw material components are mixed and pulverized, and then granulated under optimum conditions to prepare. Since the powdery or granulated skin cleansing material does not contain water as compared with the liquid or gel-like skin cleansing material, it can provide high safety without disposing of the preservative and the bactericide and having no burden on the skin. product. However, the powdery or granulated skin cleansing material has the following disadvantages: when it is dissolved in water with a palm, a sponge or the like at the time of use, it cannot be uniformly dissolved, and a block called "clump" or "powder" appears. Shape. In addition, it is pointed out that the foaming property is also inferior to the liquid or gel-like skin washing material. In particular, the N-mercapto glutamate which is a washing component used for a powdery skin cleansing material or a granulated skin cleansing material is weakly acidic, and has less irritation to the skin, thereby serving as a highly safe washing component. However, it is widely used, but on the other hand, it is pointed out that it is difficult to dissolve in water, and the foaming property is poor when it is made into a powdery washing material.

The applicant of the present application has proposed a powdery skin cleansing material which is formulated with a cationized dextran in a powdery skin cleansing preparation, so that it has high safety and contains a powder of N-mercapto glutamate when used. The solubility of the cleaning material is improved, and the foaming property is also excellent, and the roughness is not generated when foaming with a palm or the like, and the usability is improved (Patent Document 1: Japanese Patent No. 4712222).

Further, there has been proposed a powdery detergent composition which is excellent in foaming property of N-mercapto glutamine or higher fatty acid salt, polyamino acid and neutral amino acid (Patent Document 2) : Japanese Patent No. 4253687).

In addition, a powdery detergent is prepared which is formulated with N-mercapto glutamate, a branched dextran having a cyclic structure, hydroxypropyl starch phosphate, polydextrose and The foaming property is excellent (patent document 3: Japanese Patent No. 5662986).

However, regarding the powdery skin cleansing material and the granular skin cleansing material, further improvement in the foaming speed and the properties of the foaming material is sought.

On the other hand, the N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate used in the present invention is formulated into a liquid skin cleansing agent by supplying an aqueous solution. Possibly because of the difficulty in powdering, no prior art for pulverizing N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate has been found, nor has it been found to be formulated in powdered, granulated skin. An example of a washing material.

[Previous Technical Literature] [Patent Literature]

[Patent Document 1] Japanese Patent No. 4712222

[Patent Document 2] Japanese Patent No. 4253687

[Patent Document 3] Japanese Patent No. 5662986

An object of the present invention is to provide a skin cleansing composition which is improved in foaming speed and foam quality in a powdery or granulated skin cleansing composition formulated with N-mercapto glutamate. Skin cleansing composition.

The inventors of the present invention conducted various studies on the foaming and foaming of powdered skin cleansing materials prepared with N-mercapto glutamate and other surfactants, and found that when the N-fatty acid sulfhydryl group B was formulated In the case of the base-N-2-hydroxyethylglycinate, foaming and foaming of the powdery or granulated skin cleansing material are remarkably improved, thereby completing the present invention.

The present invention has the following constitution.

(1) A powdery or granulated skin cleansing composition comprising N-mercapto glutamate and N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate .

(2) The skin cleansing composition according to (1), wherein the N-mercapto glutamate and the N-fatty acid decylaminoethyl are formulated in a mass ratio of 100:1 to 1:1. -N-2-hydroxyethylglycinate.

(3) The skin cleansing composition according to (1) or (2), wherein the N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate is N-coconut fatty acid Sodium decylaminoethyl-N-2-hydroxyethylglycine or N-laurate decylamine Sodium ethyl-N-2-hydroxyethylglycine.

(4) The skin cleansing composition according to any one of (1) to (3) wherein the N-coconut fatty acid decylaminoethyl-N-2-hydroxyethylglycinate Or N-lauric acid decylaminoethyl-N-2-hydroxyethylglycolate is a powder or a particulate powder prepared by freeze-drying.

According to the present invention, it is possible to provide a powdery or granulated skin cleansing composition which is fast in foaming and excellent in foam quality.

The present invention relates to a powdery or granulated skin cleansing composition characterized by containing N-mercapto glutamate and N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate. The invention of the object.

The N-mercapto glutamate used in the present invention may, for example, be N-lauroside glutamate, N-myristyl glutamate, N-palmitate glutamate, N-stearin Gluten, N-oil glutamate, and the like. Further, as such a mixture, N-(coco fatty acid/palm oil fatty acid/sunflower oil fatty acid) thiol glutamate, N-coconut fatty acid thiol glutamate, N-palm oil fatty acid 醯 can be cited. A glutamic acid salt, an N-hydrogenated tallow fatty acid thiol glutamate or the like. Further, examples of the salt include an alkali metal salt such as sodium or potassium, an alkanolamine salt such as triethanolamine, and a basic amino acid salt such as aminic acid or arginine. N-mercapto glutamate is a cleansing ingredient known to be less irritating to the skin. In the practice of the present invention, the above N-mercapto glutamic acid has the same status, but In terms of safety and usability, it is particularly preferred to be N-(coco fatty acid/palm oil fatty acid/sunflower oil fatty acid) mercapto glutamate.

The amount of the N-mercapto glutamate used in the present invention is preferably from 1 to 99% by mass, more preferably from 10 to 50% by mass, based on the powdery or granulated skin cleansing composition. More preferably, it is 15 to 40% by mass.

The N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate used in the present invention is a compound represented by Formula 1.

N- 1 fatty acyl group of formula -N-2- ethyl hydroxyethyl glycine salt used in the present invention R ₁ is _an alkyl group having a carbon number of 7 to 17, preferably to 9 carbon atoms, 13 alkyl. Further, M is an alkali metal, preferably sodium.

N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate is a glycine-type amphoteric surfactant, which has less irritating effect on skin and mucous membranes and a stimulating effect on anionic surfactants. It is also large, so it can be used in shampoos, liquid bath soaps, facial cleansers, bath soaps, hand soaps, toothpastes. In particular, since it is excellent in foam improvement, foaming, and conditioning, it is often formulated in a conditioning shampoo. However, due to the N-fatty acid sulfhydryl group Since ethyl-N-2-hydroxyethylglycinate is supplied as an aqueous solution, it can be used only in a liquid or solid detergent, and is used for washing the powdery or granulated skin of the present invention. With the composition, some method is required for powdering. For powdering, spray drying or freeze drying is carried out.

Thus, by pulverization, N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate is initially obtained in a form suitable for the present invention. Further, in the practice of the present invention, the above N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate has the same position, but in terms of safety and usability, it is particularly preferred to be N. - Coconut oil fatty acid decylaminoethyl-N-2-hydroxyethylglycolate or N-lauric acid decylaminoethyl-N-2-hydroxyethylglycolate.

The N-coconut oil fatty acid decylaminoethyl-N-2-hydroxyethylglycine sodium used in the present invention is named as sodium cocoyl dibasic acid acetate, and as a commercial product, it can be exemplified: Softazoline CL-R manufactured by Chuanyan Fine Chemicals, NIKKOL AM-101 manufactured by Nikko Chemicals, AMPHITOL 20Y-B manufactured by Kao, and Obazoline 552 manufactured by Toho Chemical Industry Co., Ltd. Further, the labeling name of N-lauric acid decylaminoethyl-N-2-hydroxyethylglycolate is called sodium lauryl dibasic acid acetate, and as a commercial product, it can be exemplified: Chuan Yan Fine Chemicals Softazoline LHL, Obzoline 662N manufactured by Toho Chemical Industry Co., Ltd. Further, the commercially available N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate is an aqueous solution, and when used as described above, it is pulverized by treatment such as freeze drying. .

The compounding amount of the N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate used in the present invention is preferably 0.1 to 50% by mass, more preferably 0.5 to 10% by mass, particularly preferably It is 0.5 to 4% by mass.

The ratio of the N-mercapto glutamate and the N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate used in the present invention is preferably 100:1 to 1:1. It is preferably from 80:1 to 8:1, particularly preferably from 50:1 to 8:1. When the powdery or granular cleaning composition is foamed for washing the skin, the foaming can be quickly foamed, and a foam suitable for washing a face or the like can be formed to form a foam. Washing and washing your face work effectively.

In the powdery or granulated skin cleansing composition of the present invention, in addition to N-mercapto glutamate, N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate, As the surfactant, an anionic surfactant, an amphoteric surfactant, a cationic surfactant, or a nonionic surfactant which does not adversely affect the effects of the present invention can be appropriately formulated.

The anionic surfactant may, for example, be a higher fatty acid salt, N-mercaptoalanine, N-methylmethyltaurate, N-mercapto 2-hydroxyethylsulfonate or N-mercapto Gan Amine salts, monoalkyl phosphates, ether carboxylates, alkyl sulfonates, sulfosuccinates, and the like. Examples of the amphoteric surfactant include a carboxybetaine surfactant, a sulfobetaine surfactant, a guanamine betaine surfactant, and an aminopropionic acid surfactant.

The powdery or granulated skin cleansing composition of the present invention may contain a saccharide, a sugar alcohol, an organic powder, an inorganic powder, a polymer, a preservative, a chelating agent, a UV absorbing agent, an ultraviolet blocking agent, and a moisturizing agent. Agents, perfumes, pH adjusters, desiccants, and the like. It may also contain other medicinal ingredients and physiologically active ingredients.

Examples of sugars and sugar alcohols include glucose and mountains. Pearitol, mannose, mannitol, galactose, galactitol, maltose, maltitol, trehalose, erythroglucose, erythritol, xylose, xylitol, sucrose, lactose, lactitol, di fructose Anhydride, etc.

Examples of the organic powder include polyethylene powder, polystyrene powder, polymethyl methacrylate powder, nylon powder, polyurethane powder, agar powder, cork powder, and starch.

Examples of the inorganic powder include talc, kaolin, cerium oxide, mica, zeolite, bentonite, and titanium oxide.

Examples of the polymer include acacia, tragacanth, galactan, guar gum, carrageenan, pectin, sinica, sassafras, dextran, cationized dextran, polytriglucose, Carboxymethyl starch, collagen, casein, gelatin, methylcellulose, methylhydroxypropylcellulose, hydroxyethylcellulose, sodium carboxymethylcellulose (CMC), hydroxypropylmethylcellulose, Sodium alginate, carboxyvinyl polymer (trade name "CARBOPOL", etc.).

Examples of the preservative include methyl p-hydroxybenzoate and ethyl p-hydroxybenzoate.

Examples of the chelating agent include ethylenediaminetetraacetate such as disodium ethylenediaminetetraacetate, ethylenediaminetetraacetic acid, and sodium ethylenediaminetetraacetate.

Examples of the medicinal ingredient include L-ascorbic acid, L-ascorbyl phosphate, L-ascorbyl monopalmitate, L-ascorbic acid dipalmitate, and L-ascorbic acid-2-glucoside, etc. Whitening agents such as glycopeptides, saxifrage extracts, skin rejuvenation such as royal jelly and beech extract Agent, capsaicin, zingerone, canthax, fish fat, caffeine, tannin γ-oryzanol and other blood flow promoters, glycyrrhizic acid derivatives, glycyrrhetinic acid derivatives, azulene and other anti-inflammatory The agent, the maltose sucrose condensate of the resident bacteria controlling agent, the chlorinated lysozyme, and the like.

In the present invention, the effect of the present invention can be further enhanced by further blending a polyamino acid. The polyamino acid is not particularly limited as long as it is a polycondensate obtained by polycondensation of one or more amino acids having an amine group and a carboxyl group in the same molecule by an acid amide bond, and is preferably in the present invention. In order to use the polyamino acid having a degree of polymerization of about 30 to 700 in the polyamino acid thus obtained.

The polyamino acid which is preferably used in the present invention is a homopolymer obtained by polycondensing one type of amino acid. Examples of such a polyamino acid include poly(amino) acid, polyornosine, and poly Glutamic acid and the like.

In the present invention, the foaming property can be improved by further formulating a neutral amino acid. Examples of the neutral amino acid used in the present invention include glycine, alanine, valine, leucine and isoleucine which are aliphatic amino acids and are monoamine monocarboxylic acids. a fatty amino acid and a hydroxyl amino acid of serine, threonine, which is an aliphatic amino acid and is a thiol-containing acid cysteine, cystine, methionine, having The glutamic acid and aspartic acid of the amino acid of the amidino group are amphetamine and tyrosine which are amino acids having an aromatic group, and are amino acids and hydroxyindoles of an amino acid having an imine group. Amino acid. Among the neutral amino acids, a serine acid or a sulphite which is an aliphatic amino acid and is a hydroxylamino acid is preferred, and a serine acid is particularly preferred.

In addition, in the present invention, the adjustable structure has a ring structure Branched dextran, hydroxypropyl starch phosphate, polydextrose, and the like. The branched glucan having a cyclic structure used in the present invention is a compound which forms a ring in a part of a branched glucan structure, and can be produced by the production method described in JP-A-2012-120471. Specifically, by allowing the branching enzyme to act on the branched glucan, then the 4-α-glucoside transferase is allowed to act, or the 4-α-glucoside transferase is allowed to act on the branched glucan Then, the branching enzyme is allowed to act, or the branching enzyme and the 4-α-glucoside transferase act simultaneously on the branched glucan to produce a branched glucan having a cyclic structure. As the branched glucan having a cyclic structure used in the present invention, "Cluster Dextrin" manufactured by Nippon Food Chemical Co., Ltd. is mentioned.

Hydroxyalkyl starch phosphate is a substance which crosslinks hydroxyalkyl starch by phosphoric acid. Hydroxyalkyl starch is obtained by reacting starch with an alkylene oxide, for example, with ethylene oxide or propylene oxide. The hydroxyalkyl starch phosphate is exemplified by hydroxypropyl starch phosphate of Akzo Nobel, trade name "STRUCTURE XL".

Polydextrose is a water-soluble dietary fiber that is difficult to digest, and is obtained by reacting glucose, sorbitol, and citric acid. Commercially available products can be used as the polydextrose, and for example, the product name "Lai Tess ultra" manufactured by Danisco Japan can be used.

The skin cleansing composition of the present invention is in the form of powder or granules. The powdery composition can be prepared by pre-screening the raw material, adjusting the particle size to obtain a powdery raw material, and mixing the raw material of the powder by a conventional method. Further, in order to form a particulate composition, it can be obtained by granulating while spraying water or alcohol as a binder in a uniformly mixed powdery composition, and further screening to adjust the granules. degree.

The skin cleansing composition of the present invention can be used for washing and washing the body after foaming while dissolving with water or hot water.

Example

The present invention will be further illustrated by the following examples, comparative examples, test examples, and formulation examples.

<Preparation of powdery skin cleansing composition>

1. Preparation of powdered N-coconut oil fatty acid mercaptoaminoethyl-N-2-hydroxyethylglycine sodium (labeled name: sodium cocoyl dibasic acid acetate)

N-Coconut Oil Fatty Acids, mercaptoaminoethyl-N-2-hydroxyethylglycine, are surfactants developed for use in liquid shampoos and detergents, and are commercially available as liquid solutions. Therefore, in order to pulverize the commercially available N-coconut oil fatty acid mercaptoaminoethyl-N-2-hydroxyethylglycine, powdering was attempted by freeze drying.

A 30% aqueous solution of a commercially available N-coconut oil fatty acid decylaminoethyl-N-2-hydroxyethylglycolate (trade name: "Softazoline CL-R" manufactured by Kasei Fine Chemicals Co., Ltd.), and This solution was frozen in a methanol bath at -40 ° C, and then freeze-dried under a reduced pressure of 15 Pa or less for 24 hours using a freeze dryer FDU-2100 (EYELA: manufactured by Tokyo Chemical Industry Co., Ltd.) to obtain N-coconut oil fatty acid mercaptoamine group. A powder of sodium ethyl-N-2-hydroxyethylglycine.

2. Preparation of powdered skin cleansing composition

Table 1 shows the blending composition of the following compositions: Examples of the compositions of Examples 1 to 4 of the present invention, which do not contain N-coconut fatty acid mercaptoaminoethyl-N-2-hydroxyethylglycinate The composition of Example 1 (previous technique), formulated with N- Comparative Example 3 of mercapto glutamate and semipolar surfactant laurylamine oxide, disodium lauryliminodiacetate and cocoamine C formulated with amphoteric surfactant Comparative Example 2 of base betaine, composition of Comparative Example 4, comparison of all sodium glutamate glutamate to N-coconut fatty acid decylaminoethyl-N-2-hydroxyethylglycinate The composition of Example 5. Each of the powder components for blending was previously sieved to adjust the particle size, and the powder components were mixed to prepare a powdery skin cleansing composition. Further, a laurylamine oxide ("Amogen AOL", First Industrial Pharmaceutical Co., Ltd.) used in the comparative example was a material obtained by pulverizing a liquid commercial product with a freeze-drying apparatus.

<Evaluation test of powdery skin cleansing composition>

Table 1 shows the formulation composition of the following: Example 1 in which N-mercapto glutamate and N-coconut fatty acid decylaminoethyl-N-2-hydroxyethylglycinate were formulated to A powdery skin cleansing composition of 4, Comparative Example 1 in which N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate was not formulated and only N-mercapto glutamate was formulated Powdery skin cleansing composition, powdered skin of Comparative Examples 2, 3, and 4 in which N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate was replaced with another surfactant For the composition for washing, only the skin cleansing composition of Comparative Example 5 in which N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate was added was prepared. The foaming speed of the prepared powdery skin cleansing composition, the amount of foam, and the hardness of the foam were evaluated in accordance with the following criteria.

Also, due to N-coconut oil fatty acid decylaminoethyl-N-2-hydroxyethylglycine sodium (labeled name: sodium cocoyl dibasic acid acetate: trade name Chuan Yan Softazoline CL-R manufactured by Fine Chemicals Co., Ltd. and Laurylamine Oxide (Amogen AOL manufactured by Daiichi Kogyo Co., Ltd.) used in Comparative Example 3 are commercially available as a 30% aqueous solution, and are freeze-dried after pre-freezing. The machine FDU-2100 (EYELA) was freeze-dried at a pressure of 15 Pa or less for about 24 hours, and was used after pulverization.

1. Evaluation of the foaming speed

It was evaluated by 10 professional reviewers by the following methods. Take 0.6 g of each powdery skin cleansing composition in the palm of the hand, add about 2 to 3 mL of tap water, and foam with both hands for about 30 seconds, and then fully perform the foaming action so that the air is entangled in the foam. .

It is estimated that the following score is attached based on the foaming speed of the powdery skin cleansing composition of Comparative Example 1 (conventional product).

2 points: quick foaming.

1 point: The foaming speed is constant.

0 points: Slow foaming.

The average of 10 professional reviewers' scores was obtained and a comprehensive evaluation was conducted based on the following criteria.

○: 1.5 points or more and 2 points or less

×: Less than 1.5 points

2. Assessment of the amount of foam

In the evaluation of the above foaming, the amount of foam formed was evaluated while evaluating the foaming speed.

In addition, in the same manner as in the test of 1., the amount of foam of the powdery skin cleansing composition of Comparative Example 1 (conventional product) was used as a standard, and the following is attached. score.

2 points: The amount of foam is large.

1 point: The amount of foam does not change.

0 points: less foam.

The average of 10 professional reviewers' scores was obtained and a comprehensive evaluation was conducted based on the following criteria.

○: 1.5 points or more and 2 points or less

×: Less than 1.5 points

3. Evaluation of foam hardness

In the same manner, the hardness of the formed foam was evaluated by 10 professional reviewers while evaluating the foaming speed.

The following scores were attached to the foam hardness of the powdery skin cleansing composition of Comparative Example 1 as a standard.

2 points: The foam hardness is sufficient.

1 point: The foam hardness is unchanged.

0 points: The foam hardness is poor and there is no elasticity.

The average of the scores of 10 professional reviewers was obtained and evaluated according to the following criteria.

○: 1.5 points or more and 2 points or less

×: Less than 1.5 points

4. Evaluation results

The results of the comprehensive evaluation of each item are shown in Table 1 below.

Formulated with N-cocoate fatty acid decylaminoethyl-N-2-hydroxyethylglycolate (coco) in N-(coco fatty acid/palm oil fatty acid/sunflower oil fatty acid) thioglycolate The cleansing powder of Example 1 of sodium oleate diacetate has a significantly faster foaming, and the amount of foam and the hardness of the foam are excellent. Since Example 1 is fast in foaming, it also generates a large amount of foam and shows Suitable for face wash performance. Further, the foam is hard and the foam is elastic, and the feeling of use is excellent.

Comparative Example 2 in which disodium lauryldiacetate was substituted for sodium cocoyldiamide was compared with Example 1, which was inferior in foaming speed.

Comparative Example 3 in which laurylamine oxide was added in place of sodium cocoamphodiacetate was inferior to Example 1 in terms of the foaming speed, the amount of foam, and the hardness of the foam. The foaming speed is poor compared to Examples 1 to 4, which may be related to the small amount of foam. In addition, the resulting foam has a poor feeling of use.

In Comparative Example 4 in which cocoamidopropyl betaine was blended instead of sodium cocoyldiamide acetate, consolidation was caused by strong deliquescence, and thus it was impossible to measure.

Comparative Example 5 in which N-(coco fatty acid/palm oil fatty acid/sunflower oil fatty acid) sodium glutamate was completely replaced with sodium cocoyl diacetate was excellent in foaming speed, but the amount of foam and foam The hardness is poor.

From the evaluation tests using the foaming speed, the amount of foam, and the quality (hardness) of the foam of the above examples and comparative examples, it was found that in order to obtain an optimum powdery skin cleansing composition, it is necessary to formulate N-bismuth bran. Amine salt and N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate. Further, any of the compositions of Examples 1 to 4 can be rapidly foamed without leaving a dough.

Prescription Example 1 Washing powder

Prescription Example 2 Washing powder

Prescription Example 3 Washing powder

Claims (4)

A powdery or granulated skin cleansing composition comprising N-mercapto glutamate and N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate. The skin cleansing composition according to claim 1, wherein the N-mercapto glutamate and the N-fatty acid decylaminoethyl are formulated in a mass ratio of 100:1 to 1:1. -N-2-hydroxyethylglycinate. The skin cleansing composition according to claim 1 or 2, wherein the N-fatty acid decylaminoethyl-N-2-hydroxyethylglycinate is an N-coconut oil fatty acid sulfhydryl group. Sodium hydroxyethyl-N-2-hydroxyethylglycine or sodium decylaminoethyl-N-2-hydroxyethylglycolate. The skin cleansing composition according to any one of claims 1 to 3, wherein the N-coconut fatty acid decylaminoethyl-N-2-hydroxyethylglycinate or N - Sodium decylaminoethyl-N-2-hydroxyethylglycolate is a powder or a particulate powder prepared by freeze drying.