TW201336428A - Semi-solidified nutritive agent - Google Patents

Abstract

[Problem] To provide a semi-solidified nutritive agent in which the occurrence of syneresis is minimized. [Solution] A semi-solidified nutritive agent comprising at least: a nutrient including a carbohydrate and a protein source; water; agar; and at least one type of thickener selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum; wherein the amount of agar contained is 0.1-0.8 mass% in relation to the total amount of nutritive agent, and the amount of thickener contained is 0.2-1.0 mass% in relation to the total amount of nutritive agent.

Description

Semi-solidified nutrient

The present invention relates to a semi-solidified nutritional supplement.

In recent years, the nutrient supply means as an alternative food has focused on the nutrient for easily taking the desired nutrients. The nutrient is known to have a solid shape, a semi-solid shape, a liquid form, and the like. Among them, the semi-solid shape nutrient can be used as a nutrient supply means in the medical field and the food field, and is gradually popularized.

The above-mentioned semi-solidified nutrient in the medical field is mainly suitable for patients, infants and elderly people, and the administration methods are roughly classified into oral administration and administration.

Oral administration is mainly applied to people with dysphagia caused by difficulty in chewing or swallowing, such as Cerebral Vascular Disorder (CVD). It is difficult for people with dysphagia to adequately take a general diet. In particular, when water or low-viscosity soup or the like is ingested, since the swallowing ability is low, it is necessary to sufficiently consider the situation of backflow and collapse. In a general hospital, a commercially available tackifier is mixed with a liquid nutrient, tea, or the like, and an action such as administration is performed by imparting an appropriate viscosity. However, if too much tackifier is added, it will partially agglomerate, and there will be a residue in the pharyngeal head, and since it takes a certain time from the addition of the tackifier to the food to the appearance of viscosity (stability of viscosity), it is modulated. There are problems that need to be worked down.

In recent years, various semi-solidified nutritional supplements have been developed for those who have difficulty swallowing. The properties required for the semi-solidified nutrient can be enumerated Such as: moderate viscosity, moderate shape retention, not easy to adhere to the mouth and pharynx, and not easy to dehydrate. In addition, from the viewpoints of improvement in nutritional status or improvement in QOL (quality of life), it is expected to have properties such as high nutritional value, excellent food texture, and flavor.

The administration is mainly for the elderly and patients who cannot be administered orally, and the semi-solidified nutrient is administered by the enteral nutrition method.

In general, the enteral nutrition system is a nutrient method for the purpose of satisfying the needs of calories and nutrients (protein sources, minerals, vitamins, etc.) required for living organisms, and is second to the physiological person who is ingested orally. Therefore, for patients who cannot be orally ingested and whose intestinal function is functioning normally, the enteral nutrition method is generally selected as compared with the intravenous parenteral nutrition (TPN: Total parenteral nutrition). In the above-mentioned enteral nutrition method, the administration method of the nutrient agent may be, for example, administration using an oral stomach tube, administration using a nasogastric tube, administration using a gastrostomy, etc., but using semi-solidification. When the nutrient is used, it is mainly selected to use the stomach stoma. In this case, the properties to be obtained may be, for example, moderate viscosity, when the stomach is administered through a tube, the nutrient is not easily left in the tube, and the tube is not easily stained. Especially in terms of viscosity, it is important to maintain high viscosity. When a nutrient having a low viscosity is administered by a gastrostomy, depending on the state of the patient, the nutrient may flow from the stomach to the esophagus, and there may be problems such as esophagitis or pneumonia.

In addition, the above-mentioned semi-solidified nutrient in the food field is mainly suitable for portable foods and diet foods because of its unique food texture and easy and rapid intake of nutrients. Nowadays, due to the high health orientation in recent years, it is sold: not only the nutrients needed for daily life, but also the body. A specific health food for a specific health function component related to physiological functions or biological activities, and a nutritious food product which may be insufficient in nutrients.

The above semi-solidified nutritional supplements have so far been reported in various ways. For example, Patent Document 1 discloses a semi-solidified nutrient for adding acacia or whole egg as a semi-solidifying agent to an enteral nutrient as a semi-solidified nutrient for enteral nutrition. Further, Patent Document 2 discloses a colloidal enteral nutrient characterized by blending acacia, alginic acid and/or a salt thereof.

[Previous Technical Literature] [Patent Literature]

[Patent Document 1] Japanese Patent No. 3516673

[Patent Document 2] Japanese Patent Laid-Open Publication No. 2008-69090

However, as shown in Patent Document 1, the semi-solidified nutrient prepared by blending a large amount of acacia tends to be gel-like, so that it is broken when transported or dropped during transportation. That is, there is a case where dehydration occurs. For example, when a nutrient which produces dehydration is ingested, for example, the viscosity and shape retention of the nutrient which are appropriately set for use may change, for example, gastroesophageal reflux or vomiting, diarrhea, and the like may occur. In addition, elderly people who have difficulty in chewing and swallowing, or patients who cannot take it by mouth, may suffer from aggravation or aspiration pneumonia due to dehydrated water. Further, there are problems such as deterioration in stability or operability due to generation of dehydration.

Further, as shown in Patent Document 2, a semi-solidified nutrient prepared by using alginic acid together with acacia, since sodium alginate itself reacts with calcium ions to form agglomerates, it is easy to form an uneven semi-solidified nutrient. .

Accordingly, it is an object of the present invention to provide a semi-solidified nutrient which inhibits the occurrence of syneresis.

[Problems to be solved by the invention]

As a result of intensive research by the inventors of the present invention, it has been found that the above problems can be solved by including a predetermined amount of acacia and a predetermined amount of a tackifier in the semi-solidified nutrient, and the present invention has been completed. That is, the present invention relates to at least one of a nutrient containing a saccharide and a protein source, moisture, a seaweed, and a group selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum. A semi-solidified nutrient for the tackifier. The content of the above-mentioned amaranth is 0.1 to 0.8% by mass based on the total amount of the nutrient, and the content of the above-mentioned tackifier is 0.2 to 1.0% by mass based on the total amount of the nutrient.

According to the present invention, a semi-solidified nutrient for inhibiting the occurrence of syneresis can be provided.

[To implement the type of invention] [semi-solidified nutrient]

The semi-solidified nutrient of the present invention comprises at least: a nutrient containing saccharide and protein source, moisture, amaranth, and at least a group selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum. a kind of tackifier, The content of the above-mentioned amaranth is 0.1 to 0.8% by mass based on the total amount of the nutrient, and the content of the above-mentioned tackifier is 0.2 to 1.0% by mass based on the total amount of the nutrient.

[nutrition]

Nutrients must contain glycogen and protein sources. The above nutrient may further contain, as an optional component, at least one selected from the group consisting of a lipid, a vitamin, a mineral, and a dietary fiber.

The total amount of nutrients in the semi-solidified nutrient is preferably 10 to 50% by mass, more preferably 20 to 35% by mass.

(glycogen)

Glycogen, also known as carbohydrate, is the source of energy.

The usable saccharide is absorbed by the living body and is an energy source, and is not particularly limited, and examples thereof include a monosaccharide, a disaccharide, and a polysaccharide. Specific examples of the monosaccharide include glucose, fructose, and galactose. Specific examples of the disaccharide include sucrose, lactose, maltose, isomaltose, and trehalose. Specific examples of the polysaccharide include starch (amylose, amylopectin), dextrin, and the like. Among these, it is better to use dextrin.

The dextrin coefficient is a general term for a substance in which a-glucose is polymerized by a glycosidic bond, and can be obtained by hydrolyzing starch. In the dextrins, the decomposition rate in the small intestine is slowed down and the absorption is slow, so that the blood sugar can be prevented from rising sharply. Further, by using dextrin, the osmotic pressure of the semi-solidified nutrient can be reduced, and the osmotic pressure can be prevented. The dextrin may be any one of a polymer dextrin having a high degree of polymerization of a-glucose and a low molecular weight dextrin dextrin having a degree of a-glucose, and it is preferred to use a polymer dextrin which can lower the osmotic pressure. this In addition, low molecular ablextatin, also known as maltodextrin, is generally a polymer of 3 to 5 a-glucose.

The dextrin can be prepared by itself or by a commercially available person. In the preparation of dextrin, conventional starch, for example: corn, waxy corn, wheat, rice, waxy rice, waxy milo, beans (broad beans, mung beans, small red beans) The starch contained in the potato, sweet potato, cassava, etc. can be prepared by hydrolysis in a conventional manner. In addition, commercially available dextrin can be applied, for example, to TK-16 (manufactured by Matsutani Chemical Industry Co., Ltd.).

These saccharides may be used singly or in combination of two or more.

The saccharide content in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject, and is preferably 5 to 25% by mass based on the total amount of the semi-solidified nutrient.

(protein source)

The protein source is not particularly limited, and a known person can be used. For example, an amino acid, a peptide, a vegetable protein, an animal protein, etc. are mentioned.

The amino acid may, for example, be valine, leucine, isoleucine, lysine, methionine, phenylalanine, Essential amino acids such as threonine, tryptophan, histidine, etc.; and glycine, alanine, serine, cysteine Cysteine, asparagine, glutamine, proline, tyrosine, aspartic acid, glutamic acid Glutamic acid), a non-essential amino acid such as arginine. In addition to this, it also contains 4-hydroxyproline, 5-hydroxy lysine, γ-carboxy glutamic acid, O-Phosphoserine, O-Phosphotyrosine. Modified amines such as O-acetylserine, N ^ω -methyl arginine, Pyroglutamic acid, MN-N-formylmethionine Base acid; ornithine, citrulline, GABA, thyroxine, S-Adenosylmethionine Amino acid. Further, the above amino acids may be stereoisomers (enantiomers, differeromers), may be positional isomers (Regioisomer), or may be a mixture thereof. . Further, the amino acid may be in the form of a mineral acid salt (hydrochloride or the like), an organic acid salt (acetate or the like), or an ester body (methyl ester or the like) which can be hydrolyzed in a living body.

The peptide can be obtained by polymerizing two or more of the above amino acids via a peptide bond (melamine bond). The peptide may be a dipeptide, a tripeptide, an oligopeptide (about 10 amino acids), or a polypeptide (approximately tens to hundreds of amino acids). Further, some oligopeptides, for example, lactopeptide, casein dodecapeptide, and sardine peptide containing valyryl tyrosine, have health functions such as antihypertensive action.

Examples of the vegetable protein include proteins contained in rice such as rice, beans such as soybeans and tofu, and the like. Further, the soybean protein binds to bile acid and has a health function of promoting cholesterol excretion and the like.

Examples of the animal protein include proteins contained in eggs, meat, fish and shellfish, milk, and the like.

Among these, whey protein using milk (whey) as a raw material is used. The casein protein and soy protein contained in the milk and milk are preferred, and the use of whey protein is preferred. Examples of the whey protein include concentrated whey protein (WPC: whey protein concentrate), whey protein isolate (WPI: whey protein isolate), and hydrolyzed whey peptide (WPH: Whey Peptide Hydrolysate). For example, WPI 18855 (manufactured by Fonterra Co., Ltd.), WPI 18852 (manufactured by Fonterra Co., Ltd.), WPI1895 (manufactured by Fonterra Co., Ltd.), WPC392 (manufactured by Fonterra Co., Ltd.), WPC, WPI, and soy protein, etc., may be used. WPC80 (manufactured by Fonterra), WPC7009 (manufactured by Fonterra), WPC164 (manufactured by Fonterra), WPC162 (manufactured by Fonterra), WPC132 (manufactured by Fonterra), WPC472 (manufactured by Fonterra), Proleena 900 ( Fuji Oil Co., Ltd.) ) Manufacturing), New fuji-pro 3000 (manufactured by Fuji Oil Co., Ltd.), New fuji-pro 1700 (manufactured by Fuji Oil Co., Ltd.), etc.

These protein sources may be used singly or in combination of two or more. The content of the protein source in the semi-solidified nutrient may be appropriately adjusted depending on the intended subject, and is preferably from 1 to 18% by mass based on the total amount of the semi-solidified nutrient.

(lipid)

Lipids can be used as a raw material for energy sources, biofilm constituents, steroid hormones and bile acids.

The lipid to be used is not particularly limited, and examples thereof include saturated fatty acids, unsaturated fatty acids, vegetable oils, animal fats and oils, and fish oils.

Examples of the saturated fatty acid include caprylic acid, capric acid, lauric acid, palmitic acid, and stearic acid.

Examples of the unsaturated fatty acid include oleic acid, palmitoleic acid, linoleic acid, peanut oleic acid, a-linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA: Docosahexaenoic acid). )Wait. In addition, EPA and DHA have health care functions such as an effect of suppressing an increase in blood cholesterol and an action of suppressing an increase in neutral fat.

The vegetable oil may, for example, be coconut oil, corn oil, cottonseed oil, olive oil, palm oil, palm kernel oil, peanut oil, rapeseed oil, safflower oil (safflower oil), sesame oil, soybean oil, sunflower oil, almond oil, Cashew nut oil, hazelnut oil, Australian walnut oil, mongongo oil, pecan oil, pine nut oil, pistachio oil, walnut oil, cucurbit seed oil, and Cucurbita foetidissima oil , pumpkin seed oil, watermelon seed oil, Amaranthus oil, apricot oil, apple oil, Argan oil, avocado oil, Babassu oil, moringa seed Oil), Borneo Tallow, Capesize Nut Oil, Cocoa Butter, Carob Oil, Cohune Palm, Quail Seed Oil, Wild Mango (Irvingia gabonensis) Oil, Linseed Oil, grape seed oil, hemp oil, kapok oil, Lallemantia iberica, Marula Oil, white mango seed oil (Meadowfoam Seed Oil), mustard oil, nutmeg (nutmeg butter), okra oil, papaya oil, perilla oil, brazil nut oil, pine nut oil, Poppy oil, western plum oil, quinoa oil, nigar seed oil , rice bran oil, royle oil, sacha inchi oil, camellia oil, Cirsium oil, tomato-seed oil, small Wheat oil, oyster sauce, sunflower oil, germ oil, coconut oil, peanut oil, etc.

Examples of the animal fats and oils include lard, tallow, and milk fat. The fish oil may be exemplified by fish oil such as squid, squid, squid, sardine, and saury.

Among these, it is preferred to use linoleic acid which is not synthesized in the human body, and a-linolenic acid or a lipid containing the same.

These lipids may be used singly or in combination of two or more.

The lipid content in the semi-solidified nutrient may be appropriately adjusted depending on the intended subject, but it is preferably from 0 to 10% by mass based on the total amount of the semi-solidified nutrient.

(vitamin)

Vitamins are a general term for carbohydrates, protein sources, and organic compounds other than lipids required to maintain the nutritional state of the organism.

Examples of vitamins include vitamin A (retinol), vitamin D (Ergocalciferol, Cholecalciferol), vitamin E (Tocopherol, Tocotrienol). ), fat-soluble vitamins such as vitamin K (phylloquinone, menaquinone); vitamin B1 (Thiamine), vitamin B2 (Riboflavin), vitamin B3 ( Niacin, Vitamin B5 (Pantothenic acid), Vitamin B6 (Pyridoxal Pyridoxamine, Pyridoxine), Vitamin B7 (Biotin) ), water-soluble vitamins such as vitamin B9 (folic acid), vitamin B12 (Cyanocobalamin, Hydroxocobalamin), Vitamin C (ascorbic acid). These vitamins may be used singly or in combination of two or more.

The vitamin content in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject. In general, for fat-soluble vitamins, an amount which does not cause an Excess symptom is added, and there is no limitation on the amount of addition of the water-soluble vitamin. The preferred content of each of the vitamins per 100 g of the semi-solidified nutrient is as follows.

[fat-soluble vitamins]

Vitamin A: preferably 0 to 3000 μg, more preferably 20 to 200 μg; vitamin D: preferably 0.1 to 50 μg, more preferably 0.1 to 5.0 μg; vitamin E: preferably 0.2 to 800 mg, more preferably 1 to 10 mg; vitamin K: preferably from 0.5 to 1000 μg, more preferably from 2 to 50 μg;

[water soluble vitamins]

Vitamin B1: preferably 0.01 to 40 mg, more preferably 0.1 to 5 mg; vitamin B2: preferably 0.01 to 20 mg, more preferably 0.05 to 5 mg; nicotinic acid (equivalent): preferably 0.1 to 300 mg NE, more preferably It is 0.5 to 30 mg of NE; pantothenic acid: preferably 0.1 to 55 mg, more preferably 0.2 to 10 mg; vitamin B6: preferably 0.01 to 60 mg, more preferably 0.1 to 10 mg; biotin: preferably 0.1 to 1000 μg, more preferably 1 to 100 μg; folic acid: preferably 1 to 1000 μg, more preferably 10 to 200 μg; vitamin B12: preferably 0.01 to 100 μg, more preferably 0.2 to 60 μg; vitamin C: preferably 1 to 2000 mg, more preferably It is 5 to 1000 mg.

(mineral)

Minerals are elements other than organic compounds required to maintain the nutritional status of the organism.

Examples of the minerals include macro-elements such as sodium, potassium, calcium, phosphorus, and magnesium; and essential trace elements such as iron, zinc, copper, iodine, manganese, selenium, chromium, and molybdenum. These minerals may be used singly or in combination of two or more.

The mineral content in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject. The preferred content of each mineral per 100 g of semi-solidified nutrient is as follows.

[mass elements]

Sodium: preferably 5 to 6000 mg, more preferably 10 to 3500 mg; potassium: preferably 1 to 3500 mg, more preferably 25 to 1800 mg; calcium: preferably 10 to 2300 mg, more preferably 30 to 300 mg; It is preferably 1 to 3500 mg, more preferably 25 to 1500 mg; magnesium: preferably 1 to 740 mg, more preferably 10 to 150 mg;

[Required trace elements]

Iron: preferably from 0.1 to 55 mg, more preferably from 1 to 10 mg; zinc: preferably from 0.1 to 30 mg, more preferably from 1 to 15 mg; copper: preferably from 0.01 to 10 mg, more preferably from 0.06 to 6 mg; It is preferably 0.1 to 3000 μg, more preferably 1 to 150 μg; manganese: preferably 0.01 to 11 mg, more preferably 0.1 to 4 mg; selenium: preferably 0.1 to 450 μg, more preferably 1 to 35 μg; 0.1 to 40 μg, more preferably 1 to 35 μg; molybdenum: preferably 0.1 to 320 μg, more preferably 1 to 25 μg;

(food fiber)

Food fiber line has prevention: reduced nutrient availability, plasma cholesterol The function of alcohol reduction, improvement of blood glucose response, improvement of colorectal function, and prevention of colorectal cancer. Further, the dietary fiber is also fermented by intestinal bacteria and converted into a short-chain fatty acid, a carbonic acid gas, a hydrogen gas, a methane gas or the like. Among them, in terms of short-chain fatty acids, dietary fibers may become an energy source because they are absorbed by the large intestine.

The dietary fiber is not particularly limited, and examples thereof include cellulose, hemicellulose, lignin, insoluble pectose, chitin, chitosan, and Psyllium seed husk. Insoluble dietary fiber such as low molecular weight sodium alginate; water soluble pectin, guar gum, konjac mannan, glucomannan, alginic acid, acacia, chemically modified polysaccharides ( Chemically Modified Polysaccharides), polydextrose, indigestible fructooligosaccharides, maltitol, inulin, carrageenan, wheat bran, indigestible dextrin (eg: Pine) A water-soluble dietary fiber such as a fiber-C (manufactured by Matsutani Chemical Industry Co., Ltd.), a polydextrose or a guar gum decomposition product, etc. These dietary fibers may be used singly or in combination of two or more.

The dietary fiber content in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject.

[moisture]

The semi-solidified nutrient of the present invention suitably contains moisture.

The moisture content in the semi-solidified nutrient may be appropriately adjusted depending on the intended object or the desired viscosity, etc., and is preferably 40 to 90% by mass based on the total amount of the semi-solidified nutrient.

[agar]

The semi-solidified nutrient of the present invention preferably comprises from 0.1 to 0.8% by mass, more preferably from 0.3 to 0.6% by mass, based on the total amount of the semi-solidified nutrient. The semi-solidified nutrient can improve water retention and inhibit dehydration by containing a predetermined amount of a tackifier and the above-mentioned content of agar.

The polysaccharides of the red algae such as the stone cauliflower and the genus Gracilaria vermiculophylla are frozen and dried, and are mainly composed of polysaccharides such as acacia powder or agaropectin. The above-mentioned acacia powder or gelatin sulfur has a structure in which galactose and 3,6-anhydrogalactose are mutually polymerized. The traits of different flavors or molecular weights of the seaweed powder or the sulphur sulphate, the content of the sulphate group and the pyruvate group in the sauerkraut, but in the semi-solidified nutrient of the present type There is no special restriction and either one can be used. Moreover, when a highly elastic amaranth is used, the semi-solidified nutrient tends to be a nearly solid gel. On the other hand, when a soft-skinned amaranth is used, the semi-solidified nutrient tends to become a nearly liquid paste. Commercial products can be used, for example, Ultra Agar UX30 (manufactured by Ina Food Industry Co., Ltd.), Ultra Agar UX100 (manufactured by Ina Food Industry Co., Ltd.), Ultra Agar AX30 (manufactured by Ina Food Industry Co., Ltd.), Ultra Agar AX- 100 (manufactured by Ina Food Industry Co., Ltd.), Ultra Agar BX30 (manufactured by Ina Food Industry Co., Ltd.), Ultra Agar BX-100 (manufactured by Ina Food Industry Co., Ltd.), and the like.

[tackifier]

The semi-solidified nutrient of the present invention comprises a tackifier selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum.

The tackifier content of at least one selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum in the semi-solidified nutrient, relative to the total amount of the semi-solidified nutrient, 0.2 It is preferably 1.0% by mass. When the content of the tackifier is less than 0.2% by mass, it is difficult to maintain water retention and dehydration occurs. When the content of the above tackifier exceeds 1.0% by mass, there is a tendency to stick more. The content is preferably from 0.3 to 0.6% by mass.

The semi-solidified nutrient of the present type may further contain a tackifier other than the above tackifier.

Other examples of tackifiers are not particularly limited, but gelatin, guanidine mannose, sanxian gum, tamarind gum, carrageenan, propylene glycol, carboxymethyl cellulose, lanolin, tara gum (Tara gum) can be used. ), tamarind gum, psyllium guar gum, gum arabic, carterulgo polysaccharide, polytriglucose, sodium alginate, tragacanth gum, karaya gum, acetamate aluminum (Veegum) and the like. These tackifiers may be used singly or in combination of two or more.

[Other ingredients]

The semi-solidified nutrient of this type may further contain other conventional ingredients such as health care functional ingredients, food additives, tackifiers and the like.

[Health function ingredients]

The health function component is a component that exerts a certain function on the living body by ingestion. The health functional ingredients such as indigestible fructooligosaccharide, sugar alcohol, calcium citrate malate (CCM), and casein phosphopeptide (CPP) can be enumerated, for example, chitosan, L-arab. Sugar, guava leaf polyphenols, wheat bran, soybean meal extract, diacylglycerol, dimercaptoglycerol plant sterol, soy isoflavones, Milk basic protein (MBP: Milk Basic Protein) and the like.

[Indigestible Fructooligosaccharide]

The indigestible fructooligosaccharide refers to a sugar having a large molecular weight (about 300 to 3,000) in a compound in which a monosaccharide is bonded by a Glycosidic bond. The above-mentioned indigestible fructooligosaccharide cannot be decomposed by the digestive enzymes of the human body, and is contained in the above-mentioned saccharide for the decomposing enzymes which can be decomposed by the human body. The intestine effect can be obtained by ingesting indigestible fructooligosaccharides.

The indigestible fructooligosaccharide is not particularly limited, and examples thereof include xylo oligosaccharide, fructo-oligosaccharide, soybean oligosaccharide, isomaltto-oligosaccharide, and milk. Lacto-sucrose, lactulose, galactooligosaccharide, and the like. These indigestible fructooligosaccharides may be used singly or in combination of two or more.

The indigestible fructooligosaccharide content in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject.

[sugar alcohol]

A sugar alcohol is a kind of sugar which is produced by reduction of a carboxyl group of an aldose or a ketose, and is poorly absorbed from the small intestine to the body and is difficult to be a calorie. Sugar alcohol is not easily metabolized by the acid produced by the bacteria in the mouth, and prevents the formation of tartar. This sugar alcohol can be used as a low-calorie sweetener.

The sugar alcohol may, for example, be erythritol, maltitol, palatinose or the like. These sugar alcohols may be used singly or in combination of two or more.

The content of the sugar alcohol in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject.

Calcium citrate malate (CCM) and casein phosphopeptide (CCP) CCM and CPP promote calcium absorption and promote bone formation. The CCM and CPP can be used singly or in combination. Also, CCM and CPP are preferred for the combined use of calcium.

The content of CCM and CPP in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject.

(Food Additives)

The food additive is used by adding, mixing, wetting or other methods to the food for the purpose of processing or preserving the food. The food additive may be, for example, zinc gluconate, copper gluconate, ascorbic acid diglucoside, cyclodextrin, preservative, antifungal agent, antioxidant, coloring agent, sweetener, pH adjustment. Agents, acidifiers, emulsifiers and fragrances, etc.

[Zinc Gluconate and Copper Gluconate]

Zinc gluconate and copper gluconate utilize gluconate, which is a high chelation energy with heavy metal ions of gluconic acid. When it is in the form of gluconate, it is easily absorbed, so it can effectively absorb zinc and copper. The zinc gluconate and copper gluconate may be used singly or in combination.

The content of zinc gluconate and copper gluconate in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject.

[ascorbic acid diglucoside]

Ascorbic acid diglucoside is at the 2-position of vitamin C (ascorbic acid) A compound in which agglomerated glucose is a-coordinated, because it is not attacked by oxygen, it is a vitamin C derivative which is higher in stability than general vitamin C. Vitamin C can be effectively absorbed by ascorbyl diglucoside.

The content of ascorbic acid diglucoside in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject.

[cyclodextrin]

The cyclodextrin-based glucose is bonded via a glucosidic bond to form a cyclic oligosaccharide having a cyclic structure. The one formed by six glucoses is called a-cyclodextrin, the one made up of seven glucoses is called ß-cyclodextrin, and the one made up of eight glucoses is called γ-cyclodextrin. The cyclodextrin has a function of suppressing allergy, suppressing an increase in blood sugar level, and emulsification. The cyclodextrin may be used singly or in combination of two or more.

The cyclodextrin content in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject.

[Antioxidants]

The antioxidant has a function of preventing deterioration due to oxidation of the semi-solidified nutrient.

The antioxidant is not particularly limited, and ascorbic acid and its sodium salt, Erythorbic acid and its sodium salt can be used. These antioxidants may be used singly or in combination of two or more.

[Colorant]

The colorant has the function of beautifying the semi-solidified nutrient.

There are no special restrictions on the coloring agent, but edible tar pigments (food color red No. 2, No. 3, No. 40, No. 102, No. 104, No. 105) can be used. And No. 106; food coloring blue No. 1, No. 2; food coloring yellow No. 4, No. 5; food coloring green No. 3, etc.), ß-carotene (s-carotene), water-soluble fruit red (annatto), chlorophyll Derivatives (chlorophyll a, chlorophyll b, chlorophyll copper, chlorophyll copper sodium, chlorophyll iron sodium), riboflavin, iron oxide, titanium dioxide, safflower yellow pigment, magenta pigment, gardenia yellow, turmeric Curcumin, red cabbage pigment, beet red pigment, grape skin pigment, capsicum pigment, caramel, etc. These coloring agents may be used singly or in combination of two or more.

[sweetener]

The sweetener has a function of imparting sweetness to the semi-solidified nutrient.

There are no special restrictions on sweeteners, but saccharin and its sodium salt, xylitol, aspartame, sucralose, oxafunk, sweetener, cyclamate (cyclohexylamine sulfonic acid), New Zealand can be used. Neotame, trehalose, erythritol, maltose, palatinose, sorbitol, licorice extract, stevia processed sweetener, somami, Curculin, disodium glycyrrhizinate, etc. . These sweeteners may be used singly or in combination of two or more.

[pH adjuster]

The pH adjuster has the function of adjusting the pH of the semi-solidified nutrient.

The pH adjuster is not particularly limited, and citric acid, gluconic acid, succinic acid, potassium carbonate, sodium hydrogencarbonate, carbon dioxide, lactic acid, sodium lactate, sodium citrate, adipic acid, or the like can be used. These pH adjusters may be used singly or in combination of two or more.

The acidifying agent has a function of imparting a sour taste to the nutrient, preventing oxidation of the food, and adjusting the pH and the like.

The acidifying agent is not particularly limited, and acetic acid, citric acid, succinic acid, lactic acid, malic acid, tartaric acid, glucose, and phosphoric acid can be used. These acidifying agents may be used singly or in combination of two or more.

[emulsifier]

The emulsifier has a function of improving the solubility of oil-soluble components such as lipids in water and the like.

The emulsifier is not particularly limited, but a natural emulsifier such as lecithin, saponin or casein sodium; synthetic emulsification of glycerin fatty acid ester, sorbitan fatty acid ester, propylene glycol fatty acid ester, sucrose fatty acid ester or the like can be used. Agents, etc. These emulsifiers may be used singly or in combination of two or more.

[spices]

The fragrance has a function of scenting/smelling the semi-solidified nutrient.

There are no special restrictions on the fragrance, but acetophenone, a-pentanal aldehyde, anisaldehyde, benzaldehyde, benzyl acetate, benzyl alcohol, cinnamaldehyde, cinnamic acid, citral, citronellal, citronellol can be used. , furfural, decyl alcohol, ethyl acetate, ethyl cinnamate, ethyl decanoate, ethyl vanillin, eugenol, geranyl alcohol, isoamyl acetate, isoamyl butyrate, isoamyl phenylacetate Ester, DL-menthol, 1-menthol, methyl salicylate, piperonal, propionic acid, terpineol, vanillin, d-Borneol, and the like. These perfumes may be used singly or in combination of two or more.

[other]

Other enzymes such as a-amylase, ß-amylase, glucoamylase, glucose isomerase, trehalose-producing enzyme, trehalose-free enzyme, and glutamylase may be used.

The content of the above food additive in the semi-solidified nutrient can be appropriately adjusted depending on the intended subject.

The semi-solidified nutrient of the present type inhibits the occurrence of dehydration when a predetermined amount of a tackifier selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum is contained. The dehydration ratio of the semi-solidified nutrient is preferably 1% or less (including 1%), more preferably 0.5% or less (including 0.5%). When the dehydration rate is 1% or less (including 1%), it is preferable to maintain the viscosity and shape retention property of the semi-solidified nutrient which is appropriately set depending on the application. Meanwhile, in the present specification, the "dehydration rate" is a value measured by the method described in the examples.

Moreover, the viscosity of the semi-solidified nutrient of the present type is 10,000 to 50,000 mPa at 25 ° C. The s is better, from 15,000 to 30,000 mPa. s is better. The viscosity of the semi-solidified nutrient is 10,000 mPa. When s or more (including 10,000 mPa.s), it is preferable that gastroesophageal reflux or aspiration pneumonia is unlikely to occur. On the other hand, the viscosity of the semi-solidified nutrient is 50,000 mPa. When s or less (including 50,000 mPa.s), it is preferable because it is easy to digest. The viscosity can be adjusted by appropriately adjusting the tackifier content of at least one selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum, which is mainly a semi-solidified nutrient. Meanwhile, in the present specification, the "viscosity" is a value measured by the method described in the examples.

The heat of the semi-solidified nutrient of this type varies depending on the use of the semi-solidified nutrient, but preferably 0.5 to 2.5 kcal/g, and from the viewpoint of safety of water management, 0.5 to 1.0 kcal/ g is better, but for patients who are limited to water or those who have burned, it is 1.0 to 2.5 kcal/g. Better. This heat can be adjusted by appropriately setting the addition amount of the saccharide, lipid, amino acid or peptide, and dietary fiber. Meanwhile, in the present specification, "heat" is a value measured by the method described in the examples.

The pH of the semi-solidified nutrient of this type is preferably from 3.0 to 4.5, more preferably from 3.5 to 3.9. When the pH is in the above range, it is preferable to suppress the growth of bacteria and to obtain a refreshing feeling. This pH can be adjusted under appropriate setting of the addition amount of the pH adjuster, the acidifier, and the like. Meanwhile, in the present specification, "pH" is a value measured by the method described in the examples.

[use]

The above semi-solidified nutrient can be applied to fields such as medical treatment and food.

[medical field]

In the medical field, a semi-solidified nutrient is used, for example, as an enteral nutrient, and is applicable to enteral nutrition. The administration method of the semi-solidified nutrient in the enteral nutrition method is not particularly limited, and it is usually administered by oral administration or by using a gastric stoma. Oral administration is for elderly or sick patients who have difficulty in chewing and swallowing and have normal functions of the intestines. Further, the administration using a gastrostomy is intended for an elderly person or a patient who has difficulty in oral ingestion and has normal functions of the intestines.

The semi-solidified nutrient of the present form comprises a nutrient, a moisture, and a predetermined amount of a tackifier selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum. The content of the above-mentioned nutrients is preferably an amount which requires a calorie or a nitrogen source which is required for a living body which can satisfy the purpose of the enteral nutrition method. Moreover, the water content of the semi-solidified nutrient should be considered It is set by the state of the elderly person and the patient, the water management, and the like.

The component other than the essential component to be added to the semi-solidified nutrient of the present invention is not particularly limited, and may be appropriately set depending on the administration method, the state of the elderly or the patient to which the semi-solidified nutrient is applied, and the like. For example, it is preferable to add a sweetener, an acidulant, a flavor, or the like from the viewpoint of the improvement of the taste at the time of oral administration, the prevention of discomfort when snoring is applied, and the like. Also, in patients requiring systemic care, it is desirable to have the vitamins and minerals needed to maintain a nutritional status. In elderly people with low digestive function, food fibers are preferably added to improve constipation caused by administration of a semi-solidified nutrient.

If the semi-solidified nutrient according to the present type can inhibit the occurrence of dehydration, the semi-solidified nutrient is absorbed at a desired dynamic state, and it is difficult to cause gastroesophageal reflux or aspiration pneumonia. Furthermore, it is also possible to improve the preservability or the handleability at the time of infusion of a gastrostomy tube in the administration of a gastrostomy.

Further, since the semi-solidified nutrient of the present type can suppress the occurrence of dehydration and adjust the viscosity, the heat, the pH, and the like, for example, by adjusting the viscosity, the gastrostomy tube can be improved in the administration using the gastrostomy. Adhesion and digestibility of semi-solidified nutrient. Moreover, by adjusting the amount of heat, it is easy to manage the nutrition of an elderly person or a patient who is applying a semi-solidified nutrient. Moreover, by adjusting the pH, the preservation and cooling feeling can be improved. The viscosity, heat, pH, and the like can be controlled by appropriately adjusting the components and their contents in the semi-solidified nutrient. Further, regardless of the component or any content contained in the semi-solidified nutrient, the occurrence of dehydration can be suppressed by containing a predetermined amount of the tackifier.

[Food field]

In the food field, semi-solidified nutritional supplements are, for example, suitable for use in hobby foods.

The semi-solidified nutrient of this type comprises nutrients, moisture and a predetermined amount of a tackifier. The content of the above nutrients should be appropriately selected in accordance with the target consumer. That is, when it is used as a diet food, it is possible to set a high nutrient content, and when it is used as a nutritional supplement food for replacing a meal, a low nutrient content can be set. Further, the moisture content of the semi-solidified nutrient can be appropriately selected in consideration of the texture of the food to be produced, the throat, and the like.

The component other than the essential component is not particularly limited as long as it is added to the semi-solidified nutrient of the present invention, and can be appropriately selected depending on the food to be produced. For example, when a cooling feeling is imparted to the semi-solidified nutrient, it is preferred to add a pH adjuster to make the pH acidic. Further, in order to be recognized as a specific health food, it is necessary to contain, for example, the above-mentioned dietary fiber, indigestible fructooligosaccharide, sugar alcohol, calcium citrate malate (CCM), and casein phosphopeptide (CPP). Scheduler (health function component). Furthermore, in order to present the label of the nutritious functional food, it is necessary to make the content of the prescribed (nutritional) content of the above-mentioned vitamins, minerals, etc. within the range of the specification standard.

The semi-solidified nutrient according to the present type can suppress the occurrence of dehydration, so that energy can be appropriately supplemented, and the food can be excellent in taste.

Further, since the semi-solidified nutrient of the present type can suppress the occurrence of dehydration and adjust the viscosity, the heat, the pH, and the like, various product developments can be performed depending on the purpose. For example, a semi-solidified nutrient having different textures can be produced by adjusting the viscosity. Further, the semi-solidified nutrient agent can be produced by adjusting the heat. Moreover, by adjusting the pH, it is possible to manufacture the desired one. A semi-solidified nutrient for cooling sensation. The viscosity, heat, pH, and the like can be prepared by appropriately adjusting the components and their contents in the semi-solidified nutrient. Further, regardless of the component or any content contained in the semi-solidified nutrient, the occurrence of dehydration can be suppressed by containing a predetermined amount of the tackifier.

[Manufacturing method of semi-solidified nutrient]

The semi-solidified nutrient of this type can be produced by a known method. For example, it can be produced by adding nutrients, acacia, a tackifier and other desired ingredients to the heated water and stirring them. Furthermore, it is prepared to mix and stir the two kinds of solutions by preparing a solution in which the water is dissolved in the heated water, a solution in which the tackifier is dissolved in the heated water, and a nutrient and other desired components are added. It can be manufactured.

The resulting semi-solidified nutrient can be made into a product, for example, by filling it into a container after continuous sterilization. The method of the continuous sterilization is not particularly limited, and examples thereof include ultra-high temperature short-time (UHT) sterilization (also called instantaneous sterilization), hot water sterilization, intermittent sterilization, and the like. The above sterilization should be carried out in a short time. By performing sterilization in a short period of time, deterioration of components contained in the semi-solidified nutrient can be suppressed.

The container for filling the semi-solidified nutrient is not particularly limited, and a conventional container can be used. The container may, for example, be a Tetra Pak, a paper can, a glass container, a metal can, an aluminum pouch, a plastic container or the like. Among these, it is better to use a plastic container.

The raw materials of the above plastic containers are preferably polyethylene (PE), polypropylene (PP), polyvinyl chloride (PVC), polyvinyl acetate (PVAc), polycarbonate (PC), polybutylene terephthalate ( PBT), polyethylene naphthalate (PEN), ethylene - Vinyl acetate copolymer (EVA), ethylene-a-olefin copolymer, polyfluorocarbon, and polyimine.

In the above plastic container, the following may be further suitably used in combination: polyethylene terephthalate (PET), polyethylene naphthalate (PEN), ethylene-vinyl alcohol copolymer (EVOH). , gas barrier resin such as polyvinylidene chloride (PVDC), polyacrylonitrile, polyvinyl alcohol, polyamide, polyester, etc.; gas barrier of aluminum foil, aluminum vapor deposition film, cerium oxide film, aluminum oxide film, etc. Inorganic layer. By installing the gas barrier layer, deterioration of the semi-solidified nutrient due to oxygen, water vapor, or the like can be prevented.

The above container may also be shielded from light. By this light shielding, for example, deterioration of light such as vitamin A, vitamin B2, vitamin C, and vitamin K contained in the semi-solidified nutrient can be suppressed.

The above-mentioned container can be used, for example, a soft bag (made by Fuji Seal International), a kettle bag (made by letterpress printing), and a jointed water bottle bag (Spouch; manufactured by Dainippon Printing Co., Ltd.). ; aluminum foil packaging (Cheer pack; manufactured by Hosokawa Electric Co., Ltd.).

[Examples]

Hereinafter, the present invention will be specifically described by way of examples, but the present invention is not limited thereto. In the meantime, the "parts" or "%" used in the examples means "parts by mass" or "% by mass" unless otherwise specified.

[Examples] (Example 1)

Put 1200 parts of blended water into a 5L stainless steel bucket and warm it to 80 °C or more in a water bath. Next, add the Ultra Agar UX100 as an amaranth. (Ina Food Industry Co., Ltd.) 15 parts, 2 parts of pectin, 6 parts of locust bean gum, 2.5 parts of soybean polysaccharide, and 1 part of guar gum were dissolved. The obtained solution was cooled to 50 to 60 ° C, and 150 parts of WPC392 (Whey Protein Isolate: manufactured by Fonterra) as a protein source and TK-16 as a saccharide (dextrin: Matsutani Chemical Industry Co., Ltd.) were added. Made) 400 parts. In this solution, 60 parts of vegetable oil as a lipid and 10 parts of a glycerin fatty acid ester as an emulsifier were mixed. Furthermore, 0.3 parts of a water-soluble multivitamin as a vitamin, 1.5 parts of a fat-soluble multivitamin, and 20 parts of calcium gluconate, 10 parts of magnesium chloride, 3.2 parts of potassium chloride, 0.2 parts of sodium chloride, and phosphoric acid are added as a mineral. 10 parts of sodium dihydrogen and 6 parts of tripotassium citrate; 30 parts of guar hydrolysate as dietary fiber; 0.5 parts of synthetic yeast; 18 parts of citric acid as acidifier, 8 parts of malic acid and 27.5 parts of lactic acid; 0.6 parts of glucoside, 0.30 parts of zinc gluconate; 0.03 parts of copper gluconate and 1.5 parts of perfume were stirred. Water was added to make the resulting mixture 4,000 parts, which was dissolved and dispersed to a uniform state.

After the obtained solution was continuously sterilized, the bag was filled in an aluminum foil pouch with a stopper of 200 parts, and the container was sterilized at 90 ° C for 10 minutes. After the container is sterilized, the bagged semi-solidified nutrient is produced under cooling.

(Example 2)

A semi-solidified nutrient was produced by the same method as in Example 1 except that the protein source was changed to 120 parts of WPC392 (concentrated whey protein: manufactured by Fonterra) and the soybean protein was changed to 30 parts.

(Example 3)

In addition, the amount of the addition of the amaranth was changed to 20 parts, the amount of the pectin was changed to 4 parts, the amount of the locust bean gum was changed to 10 parts, the amount of the soybean polysaccharide added was changed to 2.5 parts, and the amount of the guar gum was added. A semi-solidified nutrient was produced by the same method as in Example 1 except that the amount was changed to 1.5 parts.

(Comparative Example 1)

In addition, the amount of the added amount of the amaranth was changed to 40 parts, the amount of the pectin added was changed to 1.5 parts, the amount of the added locust bean gum was changed to 0.5 part, the amount of the soybean polysaccharide added was changed to 2 parts, and the amount of the guar gum was added. A semi-solidified nutrient was produced by the same method as in Example 1 except that the amount was changed to 0.5 part.

(Comparative Example 2)

In addition, the amount of the added amount of the amaranth was changed to 20 parts, the amount of the pectin added was changed to 15 parts, the amount of the added locust bean gum was changed to 20 parts, the amount of the soybean polysaccharide added was changed to 10 parts, and the amount of the guar gum was added. A semi-solidified nutrient was produced by the same method as in Example 1 except that the amount was changed to 10 parts.

[Evaluation of semi-solidified nutrient]

The following evaluations were carried out for each of the semi-solidified nutrient agents obtained in the examples and the comparative examples.

<dehydration rate>

200 g of the semi-solidified nutrient was placed on a sieve of 60 mesh (mesh 300 μm: JIS specification TEST-SIEVE) and placed at room temperature of 25 °C. After 30 minutes, the weight of the liquid amount (dehydration amount) passing through the mesh was measured, and the ratio of the amount of dehydration to 200 g of the semi-solidified nutrient was determined by the following formula.

Dehydration rate (%) = (dehydration rate (g) / semi-solidified nutrient (200g)) × 100

The above dehydration rate is evaluated as a semi-solid at 24 ° C for 24 hours. The vegetative nutrient and the semi-solidified nutrient which were assumed to be stored for 7 and a half months in an accelerated test (still at 40 ° C for 4 weeks) were carried out.

<viscosity>

The viscosity of the semi-solidified nutrient was measured using a B-type viscometer DV-II+Pro (manufactured by Brookfield). The measurement was carried out for 1 minute at room temperature (25 ° C) and a rotation speed of 6 rpm.

<heat>

The general energy conversion factor, that is, based on the saccharide is 4kcal/g, the protein source is 4kcal/g, the lipid is 9kcal/g, and the dietary fiber is 2kcal/g, and the semi-solidified nutrient is obtained according to the following formula. The heat.

Calorie (kcal/g) = saccharide (g/g) × 4 (kcal / g) + protein source (g / g) × 4 (kcal / g) + lipid (g / g) × 9 (kcal / g) +Food fiber (g/g)×2 (kcal/g)

<pH>

The pH of the semi-solidified nutrient was measured using a pH meter Mettler Toledo MP220 (Mettler Toledo).

<traits>

The properties of the semi-solidified nutrient are judged by the naked eye.

○: The nutrient agent when discharged from the container has a smooth creamy appearance.

△: The nutrient agent when spit out from the container was slightly rough, and partial coagulation was observed.

X: Large aggregates or agglomerates were observed in the nutrient when spitting from the container.

<sticky>

A 50 mL Catheter tip syringe filled with a semi-solidified nutrient is connected to a tube having an inner diameter of 4 mm and squeezed by a syringe. After the total amount of the semi-solidified nutrient was released, the adhesion was evaluated according to the degree of cleansing of the semi-solidified nutrient attached to the test tube. In addition, the evaluation of adhesion was carried out according to the following criteria.

○: The inside of the test tube was washed with 20 mL of water.

×: Even if it was washed with 40 mL of water, there was still a residue of the semi-solidified nutrient in the test tube.

The results of the above evaluation of the semi-solidified nutritional supplements of Examples 1 to 3 and Comparative Examples 1 to 2 are shown together with the contents of the respective components in Table 3.

As can be seen from the results of Table 1, the semi-solidified nutrient of the embodiment is viscosified by containing at least one selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum in a predetermined amount. The agent can inhibit the occurrence of dehydration and maintain a smooth creamy trait.

Claims (4)

A semi-solidified nutrient comprising at least one of a nutrient containing a saccharide and a protein source, moisture, a seaweed, and a group selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum. In the tackifier, the content of the above-mentioned amaranth is 0.1 to 0.8% by mass based on the total amount of the nutrient; and the content of the above-mentioned tackifier is 0.2 to 1.0% by mass based on the total amount of the nutrient. For example, the semi-solidified nutrient of claim 1 of the patent scope has a viscosity of 10,000 to 50,000 mPa at 25 ° C. s. The solidified nutrient of claim 1 or 2 has a calorific value of 0.5 to 2.5 kcal/g. The semi-solidified nutritional supplement according to any one of claims 1 to 3, which has a pH of from 3.0 to 4.5.