201239358 六、發明說明： 【發明所屬之技術領域】 本發明係關於一種生化感測器’尤其關於—種利用溫度 感測器來補償檢測結果的生化感測器。 【先前技術】 圖1顯示習知生化感測器之功能方塊圖。生化感測器 2〇0包含一兩個電極211及2丨2、一參考電壓源2;2〇、一電流 電壓轉換電路230、一類比數位轉換電路24〇、_處理器25〇 及一顯示器260。於一實施例中，還可以更包含一計時器 (tuner) 27〇及一溫度感測器28〇。參考電極接觸點211用 以電連接生化測試片100的參考電極lla，工作電極接觸點 212用以電連接生化測試片1〇〇的工作電極Ub。參考電壓 源22〇可以為接地端。參考電極Ua透過參考電極接觸點2ΐι 電連接參考電壓源220 ’工作電極llb透過電極212電連接 類比數位轉換電路24〇、電流電壓轉換電路23〇及處理器 250。顯不器260電連接處理器25〇。計時器27〇用以計數， 溫度感測28G設於生化感測器内部，用以測量環境溫 度。 201239358 進行量測時，將生化測試片刚插入於生化感測器· 中使生化測3式片1〇〇的參考電極Ua與工作電極Ub間產 生一電壓差，藉以量測到一電流。類比數位轉換電路24〇及 電流電壓轉換電路230將前述電流轉換成處理器25〇能夠處 理的城，並轉前述信號計算出—血糖濃度。溫度感測器 280*感測魏溫度’處㈣25()再依據前述溫度補償前述血 糖濃度，藉以得到較正確的血糖濃度。 習知技術之生化感測器遍能夠考量到溫度對於血糖濃 度的影響，得到較正確的血糖濃度，然:而依據習知技術之生 化感測器200尚存在有更一步改善的空間。 【發明内容】 本發明-實關之目的在於提供—種生域測器。本發 明一實施例之目的在於提供—能夠測得較正破之溫度的生 化感測器。 依據本發明-實_，提供—種生化_器，適於轉接 一生化測試片，藉以檢測—檢體。生化感測器包含一第一溫 度感測益、-第二溫度感測器、—類比數位轉換電路及一處 理器。第-溫度感測器適於測得-第_溫度，第二溫度感測 器適於測得-第二溫度，類比數位轉換電路輕接於第一溫度 感測器及第二溫度感測H，處理純接於概數位轉= 201239358 路。並且處理器接收被類比數位轉換電路處理過後之第一溫 度及第一溫度，並依據第一溫度及第二溫度決定一量測處理 程序。 依據本發明一實施例，提供一種生化感測方法，被應用 於具有一第一溫度感測器及一第二溫度感測器的一生化感 測器，藉以測量一檢體。生化感測方法包含以下步驟。利用 第一溫度感測器及第二溫度感測器，分別測得一第一溫度及 —第二溫度。依據第一溫度及第二溫度決定一量測處理程 序。 於一實施例中，量測處理程序包含以下步驟。判斷第一 概度及第一溫度間差異的絕對值是否大於一預設閥值。當第 —溫度及第二溫度間差異的絕對值大於預設閥值時，依據第 一溫度及第二溫度，計算出—溫度預估值。判斷溫度預估值 疋否介於-第-操作溫度及—第二操作溫度之間。當溫度預 估值介於第—麟溫纽第二操作溫賴時，職生化感測 器配合生化職ϋ檢猶述檢體。錄赌況是，量測處理 程序更包含當溫度冊值超出第―操作溫度或第二操作溫 度時’則於生域測n的—齡器上赫—警告符號的步 驟0 於貝知例中’量測處理程序包含以下步驟。使生化感 測器測得前述檢體的-測量值。_第—溫度及第二溫度對 201239358 前述檢體的測量值進行補償，以計算出前述檢體的測量值的 一補償值。 於生化感測器以及生化感測方法的一實施例中，第—溫 度感測器及第二溫度感測器皆設於生化感測器的内部，且第 一溫度感測器的熱時間常數相異於第二溫度感測器的熱時 間常數，藉以使第一溫度感測器及第二溫度感測器形成相異 的回溫曲線。 於生化感测器以及生化感測方法的一實施例中，第一溫 度感測器設於生化感測器的内部，而第二溫度感測器設於生 化感測器的外部，且第一溫度感測器的熱時間常數相同於或 相異於第一溫度感測器的熱時間常數，藉以使第一溫度感測 器及第二溫度感測器形成相異的回溫曲線。 本發明的其他目的和優點可以從本發明所揭露的技術 特徵中得到進-步的了解。為讓本發明之上述和其他目的、 特徵和優職更·紐，下文特舉實關並配合所附圖 式，作詳細說明如下。 【實施方式】 圖2顯示依本發明—實施例之生化感測器之功能方塊 圖。如圖2所示，生化感測器300包含一兩個電極311及312、 -參考電壓源32〇、-電流電壓轉換電路33〇、—類比數位 201239358 轉換電路34〇、—虛採Vi! es - 〇〇 * 嚴理益350、一顯不窃360、一第一溫度感 、!器381及-第二溫度感測器382。於—實施例中，還可以 ^ 3 °十日可器（timer) 370。電極311用以電連接生化測 試片ίο㈣參考電極lla，電極m用以電連接生化測試片 =〇的工作 llb。參考電壓源32()可以為接地端。參考 电極Ua透過電極311電連接參考電壓源320,工作電極Ub 透過電極312電連接類比數位轉換電路34〇、電&電壓轉換 電路330及處理器35〇。顯示器36〇電連接處理器3別，計 時器370用以計數。 第一溫度感測器381及第二溫度感測器382可以為例如 —熱敏電阻，且皆設於生化感測器300内部，用以測量環境 溫度。第一溫度感測器381的熱時間常數相異於第二溫度感 測器382的熱時間常數。 進行量測時’將生化測試片1〇〇插入於生化感測器3〇〇 中’使生化測試片1〇〇的參考電極Ha與工作電極丨化間產 生一電壓差，藉以量測到一電流。類比數位轉換電路34〇及 電流電壓轉換電路330將前述電流轉換成處理器350能夠處 理的“號，並依據前述信號計算出一血糖濃度測量值。第一 溫度感測器381及第二溫度感測器382分別感測環境溫度的 一第一溫度T1及一第二溫度T2，處理器350再依據前述第 一溫度T1及第二溫度T2，決定一量測處理程序。於一實施 201239358 例中，可以依據前述第一溫度T1及第二溫度T2更進一步補 償前述血糖濃度測量值，藉以得到較正確的血糖濃度補償 值。 於一實施例中，較佳的情況是，判斷第一溫度T1及第 一溫度T2間差異的絕對值是否大於一預設閥值，當第一溫 度T1及第二溫度T2間差異的絕對值大於預設閥值時，依據 第-溫度T1及第二溫度T2計算出-魏溫度預估值。最後 再依據前述環境溫度預估值計算出前述血糖濃度測量值的 前述血糖濃度補償值。 一般而言，於正常的操作狀態下使用一個溫度感測器， 已足以測量正確之環境溫度，然而在環境溫度產生劇烈變化 時，例如彳文於中午艷陽高照時，帶著生化感測器3〇〇從室外 走進冷氣房時’因為機構上的限制，生化⑽器3⑻内部空 氣無法和外面空氣迅速對流，溫度感測器之回溫速度緩慢， 右此時使用者馬上進行量測，會因量測到錯誤的溫度而造成 麵錯誤，導錄大的縣測量結果。 圖3顯示具有相異熱時間常數的溫度感測器其時間及 溫度感測$讀值的關係圖。如圖3所示，在環境溫度產生劇 烈變化時’第—溫度感測器381及第二溫度感測器382隨溫 度變化’因兩者之熱時間常數相異，兩者之溫度的回溫曲線 LI 目異。因此’在同—時間下，第—溫度感測器 201239358 381及弟二溫度感測器382會測量到相異的第一溫度T1及第 二溫度T2，當兩溫度大於一預設閥值時，利用處理器35〇 依據第-溫度T1及第二溫度Ί7進行環境溫度的演算，藉以 計算_1麵環境溫度預雜Tetm (estimatk)n)，冑㈣ 350再依據财溫度預^Tetm對前私贿度測量值進行 補償，藉以得到較正確的血糖濃度補償值。 田此外於一實施例中，亦可以不進行補償程序，僅是依據 ’皿度預估值Tetm決定目前環境溫度是河合仙規範，並 告=使用者。於—實施例中，生化感測方法可簡來量測血 糖濃度。圖4 _依本發明-倾狀姆濃度測量方法的 流程圖。血糖濃度測量方法包含以下步騾。 步驟S02 :利用第—溫度感測器381及第二溫度感測器 382分別測得第—溫度T1及第二溫度τ2。較佳的情況是於 相同時間1下測得第-溫度Τ1及第二溫度Τ2。 少哪⑽4.判斷第—溫度 g 八 …*一恤/义1ζ間差異的絕 對值是否大於1設。於—實施财，當判斷第一溫度 T_i及第二溫度Τ2間差異的絕對值大於—預設閥值時，則顯 不警告訊息’通知使用者停止操作，鱗待1定時間後再 重新操作，此時再回到步驟S02。於一實施例中，亦可以執 仃溫度預估值Tetrn的運算，此時可以執行下—步驟伽。 步驟S〇6··依據溫度^及12，計算出—溫度預估值 201239358201239358 VI. Description of the Invention: [Technical Field] The present invention relates to a biochemical sensor, particularly to a biochemical sensor that utilizes a temperature sensor to compensate for a detection result. [Prior Art] Fig. 1 shows a functional block diagram of a conventional biochemical sensor. The biochemical sensor 2〇0 includes one or two electrodes 211 and 2丨2, a reference voltage source 2; 2〇, a current-voltage conversion circuit 230, an analog-to-digital conversion circuit 24〇, a processor 25〇, and a display. 260. In an embodiment, a timer and a temperature sensor 28 are further included. The reference electrode contact point 211 is used to electrically connect the reference electrode 11a of the biochemical test piece 100, and the working electrode contact point 212 is used to electrically connect the working electrode Ub of the biochemical test piece 1''. The reference voltage source 22〇 can be a ground terminal. The reference electrode Ua is electrically connected to the reference voltage source 220 through the reference electrode contact point 2'. The working electrode 11b is electrically connected to the analog-to-digital conversion circuit 24A, the current-voltage conversion circuit 23A, and the processor 250 through the electrode 212. The display 260 is electrically connected to the processor 25A. The timer 27 is used for counting, and the temperature sensing 28G is provided inside the biochemical sensor for measuring the ambient temperature. 201239358 When measuring, a biochemical test piece was inserted into the biochemical sensor to make a voltage difference between the reference electrode Ua and the working electrode Ub of the biochemical test piece 1 to measure a current. The analog-to-digital conversion circuit 24 and the current-to-voltage conversion circuit 230 convert the aforementioned current into a city that the processor 25 can handle, and convert the aforementioned signal to calculate a blood sugar concentration. The temperature sensor 280* senses the Wei temperature at (4) 25 () and compensates the aforementioned blood sugar concentration according to the aforementioned temperature, thereby obtaining a relatively correct blood sugar concentration. The biochemical sensor of the prior art can measure the influence of temperature on the blood glucose concentration, and obtain a relatively accurate blood glucose concentration. However, according to the conventional technology, the biosensor 200 has a room for further improvement. SUMMARY OF THE INVENTION The purpose of the present invention is to provide a seed field detector. It is an object of an embodiment of the present invention to provide a biosensor that is capable of measuring a relatively severe temperature. According to the present invention, a biochemical device is provided, which is suitable for transferring a biochemical test piece for detecting a sample. The biochemical sensor includes a first temperature sensing benefit, a second temperature sensor, an analog digital conversion circuit, and a processor. The first temperature sensor is adapted to measure the -th temperature, the second temperature sensor is adapted to measure the second temperature, the analog digital conversion circuit is lightly connected to the first temperature sensor and the second temperature sensing H , processing purely connected to the approximate digit = 201239358 road. And the processor receives the first temperature and the first temperature processed by the analog digital conversion circuit, and determines a measurement processing program according to the first temperature and the second temperature. According to an embodiment of the invention, a biochemical sensing method is provided for use in a biochemical sensor having a first temperature sensor and a second temperature sensor for measuring a sample. The biochemical sensing method includes the following steps. A first temperature and a second temperature are respectively measured by the first temperature sensor and the second temperature sensor. A measurement processing procedure is determined according to the first temperature and the second temperature. In an embodiment, the measurement processing program includes the following steps. It is determined whether the absolute value of the difference between the first degree and the first temperature is greater than a predetermined threshold. When the absolute value of the difference between the first temperature and the second temperature is greater than the preset threshold, the temperature estimate is calculated based on the first temperature and the second temperature. Determine if the temperature estimate is between - the - operating temperature and - the second operating temperature. When the temperature pre-evaluation is in the second operation temperature of the first-Linwen New Zealand, the occupational biochemical sensor cooperates with the biochemical job test to check the sample. The recording condition is that the measurement processing program further includes step 0 when the temperature book value exceeds the first operating temperature or the second operating temperature, and then the step 0 of the ageing device is detected in the field. The measurement procedure consists of the following steps. The biosensor is used to measure the measured value of the aforementioned sample. _ The first temperature and the second temperature compensate the measured value of the aforementioned specimen in 201239358 to calculate a compensation value of the measured value of the aforementioned specimen. In an embodiment of the biochemical sensor and the biochemical sensing method, the first temperature sensor and the second temperature sensor are both disposed inside the biochemical sensor, and the thermal time constant of the first temperature sensor Different from the thermal time constant of the second temperature sensor, the first temperature sensor and the second temperature sensor form a different temperature return curve. In an embodiment of the biochemical sensor and the biochemical sensing method, the first temperature sensor is disposed inside the biochemical sensor, and the second temperature sensor is disposed outside the biochemical sensor, and the first The thermal time constant of the temperature sensor is the same as or different from the thermal time constant of the first temperature sensor, so that the first temperature sensor and the second temperature sensor form a different temperature return curve. Other objects and advantages of the present invention will be apparent from the technical features disclosed herein. The above and other objects, features and advantages of the present invention will be described in detail below with reference to the accompanying drawings. [Embodiment] Fig. 2 is a block diagram showing the function of a biochemical sensor according to the present invention. As shown in FIG. 2, the biochemical sensor 300 includes one or two electrodes 311 and 312, a reference voltage source 32 〇, a current-voltage conversion circuit 33 〇, an analog numeral 201239358 conversion circuit 34 〇, a virtual Vi! es - 〇〇* 严理益350, one not stealing 360, a first temperature sense, 381 and - second temperature sensor 382. In the embodiment, it is also possible to ^ 3 ° ten timer 370. The electrode 311 is used for electrically connecting the biochemical test piece ίο (4) the reference electrode 11a, and the electrode m is used for electrically connecting the biochemical test piece = 〇 work llb. The reference voltage source 32() can be a ground terminal. The reference electrode Ua is electrically connected to the reference voltage source 320 through the electrode 311, and the working electrode Ub is electrically connected to the analog-to-digital conversion circuit 34, the electric & voltage conversion circuit 330 and the processor 35A through the electrode 312. The display 36 is electrically connected to the processor 3, and the timer 370 is used for counting. The first temperature sensor 381 and the second temperature sensor 382 may be, for example, a thermistor, and are disposed inside the biochemical sensor 300 for measuring the ambient temperature. The thermal time constant of the first temperature sensor 381 is different from the thermal time constant of the second temperature sensor 382. When measuring, ' insert the biochemical test piece into the biochemical sensor 3〇〇' to generate a voltage difference between the reference electrode Ha of the biochemical test piece 1与 and the working electrode, thereby measuring one Current. The analog-to-digital conversion circuit 34 and the current-to-voltage conversion circuit 330 convert the aforementioned current into a "number" that the processor 350 can process, and calculate a blood glucose concentration measurement value based on the aforementioned signal. The first temperature sensor 381 and the second temperature sense The detector 382 respectively senses a first temperature T1 and a second temperature T2 of the ambient temperature, and the processor 350 determines a measurement processing procedure according to the first temperature T1 and the second temperature T2. In an implementation 201239358 example The blood glucose concentration measurement value may be further compensated according to the first temperature T1 and the second temperature T2, thereby obtaining a correct blood glucose concentration compensation value. In an embodiment, it is preferable to determine the first temperature T1 and Whether the absolute value of the difference between the first temperature T2 is greater than a preset threshold, and when the absolute value of the difference between the first temperature T1 and the second temperature T2 is greater than a preset threshold, the calculation is based on the first temperature T1 and the second temperature T2 The temperature value of the out-week temperature is calculated. Finally, the aforementioned blood glucose concentration compensation value of the blood glucose concentration measurement value is calculated according to the aforementioned environmental temperature estimation value. Generally, in the normal operation state The use of a temperature sensor is sufficient to measure the correct ambient temperature. However, when the ambient temperature changes drastically, for example, when the text is high at noon, the biochemical sensor is used to enter the air-conditioning room from outside. At the time, due to the limitation of the mechanism, the internal air of the biochemical (10) device 3 (8) cannot convect rapidly with the outside air, and the temperature of the temperature sensor is slow. When the user immediately measures the right, the wrong temperature is measured. Causes a surface error, and guides the measurement results of large counties. Figure 3 shows the relationship between the time and temperature sensing and the reading of the temperature sensor with different thermal time constants. As shown in Figure 3, the ambient temperature is severe. When changing, the first temperature sensor 381 and the second temperature sensor 382 vary with temperature. Because the thermal time constants of the two are different, the temperature return curve LI of the two is different. Therefore, the same time is Next, the first temperature sensor 201239358 381 and the second temperature sensor 382 measure the different first temperature T1 and the second temperature T2. When the two temperatures are greater than a predetermined threshold, the processor 35 is used. According to the first temperature The degree T1 and the second temperature Ί7 are used to calculate the ambient temperature, so as to calculate the _1 surface temperature pre-mixed Tetm (estimatk)n), and the 四(4) 350 then compensates the pre-private bribe measurement value according to the financial temperature pre-Tetm. In addition, in an embodiment, the compensation program may not be performed, and only the current environmental temperature is determined according to the 'predicted value Tetm', and the user is quoted. - In the embodiment, the biochemical sensing method can simply measure the blood glucose concentration. Fig. 4 is a flow chart of the method for measuring the concentration of the dip in accordance with the present invention. The method for measuring blood glucose concentration comprises the following steps: Step S02: using the first temperature The sensor 381 and the second temperature sensor 382 respectively measure the first temperature T1 and the second temperature τ2. Preferably, the first temperature Τ1 and the second temperature Τ2 are measured at the same time 1. Less (10) 4. Determine whether the absolute value of the difference between the first temperature and the temperature is greater than one. In the implementation of the money, when it is judged that the absolute value of the difference between the first temperature T_i and the second temperature Τ2 is greater than the preset threshold value, the warning message 'notifies the user to stop the operation, and the scale is to be re-operated after a certain time. At this time, it returns to step S02. In an embodiment, the operation of the temperature estimation value Tetrn can also be performed, and the next step gamma can be performed. Step S〇6··Based on temperature ^ and 12, calculate - temperature estimate 201239358
Tetm依據牛頓冷卻定律（化加加，3 [撕）時間與 溫度的函數如下。 / T(t)= Tend +(τ〇 -Tend)*exp(-t/T) '式十t表示時間、Tend表示最終溫度（亦即環境 溫度）、T0表示初始溫度、exp()為指數函數、τ為熱時間常 數。在已知的時間t時，例如於5分鐘時，對第—溫度感测 器381及第二溫度感測器382進行取樣，可以分別得第—溫 度τι及第二溫度T2。因此T1&T2為已知，時間【亦為已 知、且τ|及ΐ2分別為第一溫度感測器381及第二溫度感測器 抑2的熱時間常數亦為已知，即可得到以下兩個方程式。Tetm is based on Newton's law of cooling (plus, 3 [tear) time and temperature as follows). / T(t)= Tend +(τ〇-Tend)*exp(-t/T) 'Ten t represents time, Tend represents final temperature (ie ambient temperature), T0 represents initial temperature, exp() is index The function, τ is the thermal time constant. At a known time t, for example, at 5 minutes, the first temperature sensor 381 and the second temperature sensor 382 are sampled to obtain a first temperature τι and a second temperature T2, respectively. Therefore, T1 & T2 is known, and the time is also known, and the thermal time constants of the first temperature sensor 381 and the second temperature sensor 2 are also known, and τ| and ΐ2 are also known. The following two equations.
Tl(t)— Tend +( TO -Tend)*exp(-t/xi) T2(t)- Tend +( TO -Tend)*exp(-t/T2) 其中，最終溫度（亦即環境溫度）Tend及初始溫度T〇 為未知。由於有兩個方程式及兩個未知數，因此可以求得最 終溫度Tend及初始溫度T0 ’且最終溫度Tend即為環境溫度 的溫度預估值Tetm。應了解的是，於一實施例中，亦可以在 相異的時間tl及t2下，對第一溫度感測器381及第二溫度 感測器382進行取樣，由於ti及t2亦皆為已知，計算公式 如同上述，因此省略其相關說明。 步驟S08 :判斷溫度預估值Tetm是否介於一第一操作 溫度 Tim (lower limit)及一第二操作溫度 Tum (upper 201239358 之間。 步驟S10:當溫度預估值Tetm介於一第一操作溫度Tim 及一第一操作溫度Turn之間時，則使生化感測器300配合生 化測試片100進行待測液體的測量程序。 步驟S12 :當溫度預估值Tetm超出第一操作溫度Tlm 或第二操作溫度Turn (亦即溫度預估值Tetm不在第一操作 溫度Tim或第二操作溫度Tum的範圍内）時，則於顯示器 360上顯示高溫或低溫的警告符號，以警告使用者目前所處 環境’其環境溫度已超過生化感測器300的使用規範。 圖5顯示依本發明一實施例之生化感測器之功能方塊 .圖。圖5實施例之生化感測器4〇〇相似於圖2實施例之生化 感測器300，因此相同的元件使用相同的符號，並省略其相 關說明。如圖5所示，於本實施例中，第一溫度感測器381 及第一溫度感測器382具有相同的熱時間常數，且分別設於 生化感測器300内部以及外部，第一溫度感測器381用以測 量生化感測器300内部的溫度，而第二溫度感測器382則用 其外部的溫度。當環境的溫度及生化感測器4〇〇内部的溫度 大致相同時，第一溫度感測器381及第二溫度感測器382會 測得大致相同的溫度。但當環境的溫度及生化感測器4〇〇内 部的溫度’兩者差異過大時’則亦會有兩個相異的回溫曲 線。在相同時間下所測得之第一溫度及第二溫度亦會相異。 201239358 因此，亦可以於第一溫度T1及第二溫度Τ2，兩溫度大於一 預設閥值時，利用處理器350依據第一溫度T1及第二溫度 T2计异出較正確的溫度預估值Tetm，以取代溫度感測器的 項值T1及T2。此外，於一實施例中，第一溫度感測器381 及第二溫度感測器382亦可以具有相異的熱時間常數。 此外，有時環境溫度並未改變，但使用者長期緊握生化 感測器400時，因為體溫大於環境溫度，生化感測器4〇〇内 部的溫度會上升，因此第一溫度感測器381所感測到之第一 溫度τι和第二溫度感測器382所感測到第二溫度丁2會大於 環境溫度，但ΤΙ相異於Τ2。此時，生化感測器4〇〇繼續操 作，亦會得到不正確的血糖濃度量測結果，因此可於判斷第 一溫度Τ1及第二溫度Τ2間差異的絕對值是否大於一預設閥 值，在顯示器360上顯示警告符號，並禁止使用者進行測量 程序，以避免使用者量測到不正確的血糖濃度。 依本發明一實施例，利用兩個溫度感測器來感測溫度， 較佳的情況是利用兩個具有相異回溫曲線的溫度感測器來 感測溫度，生化感測器再依據所測量到之該些溫度，決定後 續的測量程序’因此能夠測得較正確的量測結果。 雖然本發明已以較佳貫施例揭露如上，然其並非用以限 定本發明，任何熟習此技藝者，在不脫離本發明之精神和範 圍内，當可作些許之更動與潤飾，因此本發明之保護範圍當 13 201239358 視後附之巾請專纖®所界定者鱗。糾，本發明的任_ 實施例或申請專利範圍不須達成本發明所揭露之全部目的 或優點鱗點。此外’摘料分和標職是帛來獅專利文 件搜尋之用’並非用來限制本發明之權利範圍。 【圖式簡單說明】 圖1顯示習知生化感測器之功能方塊圖。 圖2顯示依本發明一實施例之生化感測器之功能方塊 圖。 圖3顯示具有相異熱時間常數的溫度感測器，其時間及 溫度感測器讀值的關係圖。 圖4顯示依本發明一實施例之血糖濃度測量方法的流程 圖。 圖5顯示依本發明一實施例之生化感測器之功能方塊 圖。 【主要元件符號說明】 100 生化測試片 lla 參考電極 lib 工作電極 2〇〇生化感測器 201239358 211 參考電極接觸點 212 工作電極接觸點 220 參考電壓源 230 電流電壓轉換電路 240 類比數位轉換電路 250 處理器 260 顯示器 270 計時器 280 溫度感測器 300 生化感測器 311 參考電極接觸點 312 工作電極接觸點 320 參考電壓源 330 電流電壓轉換電路 340 類比數位轉換電路 350 處理器 360 顯示器 370 計時器 381 第一溫度感測器 382 第二溫度感測器 400 生化感測器Tl(t) - Tend +( TO -Tend)*exp(-t/xi) T2(t)- Tend +( TO -Tend)*exp(-t/T2) where the final temperature (ie ambient temperature) Tend and initial temperature T〇 are unknown. Since there are two equations and two unknowns, the final temperature Tend and the initial temperature T0' can be obtained and the final temperature Tend is the temperature predicted value Tetm of the ambient temperature. It should be understood that, in an embodiment, the first temperature sensor 381 and the second temperature sensor 382 may also be sampled at different times t1 and t2, since both ti and t2 are already It is to be understood that the calculation formula is as described above, and thus the related description is omitted. Step S08: determining whether the temperature estimated value Tetm is between a first operating temperature Tim (lower limit) and a second operating temperature Tum (upper 201239358. Step S10: when the temperature estimated value Tetm is between a first operation When the temperature Tim and a first operating temperature Turn are between, the biochemical sensor 300 is combined with the biochemical test strip 100 to perform a measurement procedure of the liquid to be tested. Step S12: When the temperature estimated value Tetm exceeds the first operating temperature Tlm or the first When the operating temperature Turn (that is, the temperature estimated value Tetm is not in the range of the first operating temperature Tim or the second operating temperature Tum), a warning symbol of high temperature or low temperature is displayed on the display 360 to warn the user that the current location is The environment 'the ambient temperature has exceeded the specification of the biochemical sensor 300. Figure 5 shows a functional block of the biochemical sensor according to an embodiment of the present invention. The biochemical sensor of the embodiment of Figure 5 is similar to The biochemical sensor 300 of the embodiment of Fig. 2, the same components are denoted by the same reference numerals, and the related description is omitted. As shown in Fig. 5, in the present embodiment, the first temperature sensor 381 and the first temperature sense Detector 382 have the same thermal time constant and are respectively disposed inside and outside the biochemical sensor 300. The first temperature sensor 381 is used to measure the temperature inside the biochemical sensor 300, and the second temperature sensor 382 is used. The temperature of the outside. When the temperature of the environment and the temperature inside the biochemical sensor 4 are substantially the same, the first temperature sensor 381 and the second temperature sensor 382 measure substantially the same temperature. The temperature and the internal temperature of the biochemical sensor 4〇〇 'when the difference between the two is too large' will also have two different regenerative curves. The first temperature and the second temperature measured at the same time will also 201239358 Therefore, the first temperature T1 and the second temperature Τ2 can also be used. When the two temperatures are greater than a predetermined threshold, the processor 350 determines the correct temperature according to the first temperature T1 and the second temperature T2. The estimated value Tetm is substituted for the temperature values T1 and T2 of the temperature sensor. Further, in an embodiment, the first temperature sensor 381 and the second temperature sensor 382 may have different thermal time constants. In addition, sometimes the ambient temperature has not changed. When the user grips the biochemical sensor 400 for a long time, since the body temperature is greater than the ambient temperature, the temperature inside the biochemical sensor 4 上升 rises, so the first temperature τ i and the second temperature sensed by the first temperature sensor 381 The temperature sensor 382 senses that the second temperature □2 is greater than the ambient temperature, but ΤΙ is different from Τ2. At this time, the biochemical sensor 4〇〇 continues to operate, and an incorrect blood glucose concentration measurement result is also obtained. Therefore, it can be determined whether the absolute value of the difference between the first temperature Τ1 and the second temperature Τ2 is greater than a predetermined threshold, displaying a warning symbol on the display 360, and prohibiting the user from performing a measurement procedure to prevent the user from measuring the The correct blood sugar concentration. According to an embodiment of the invention, two temperature sensors are used to sense the temperature. Preferably, two temperature sensors having different rewarming curves are used to sense the temperature, and the biochemical sensor is further based on Measured to these temperatures, the subsequent measurement procedure is determined' so that the more accurate measurement results can be measured. Although the present invention has been described above in terms of a preferred embodiment, it is not intended to limit the invention, and it is obvious to those skilled in the art that the present invention may be modified and retouched without departing from the spirit and scope of the invention. The scope of protection of the invention when 13 201239358 is attached to the towel, please define the scale of the fiber. It is to be understood that the scope of the invention or the scope of the invention is not intended to be exhaustive. In addition, the 'extraction points and the subject matter are used for the search of the patent documents of the lions' are not intended to limit the scope of the invention. BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 shows a functional block diagram of a conventional biochemical sensor. Figure 2 is a block diagram showing the function of a biochemical sensor in accordance with an embodiment of the present invention. Figure 3 shows a temperature sensor with a different thermal time constant, a plot of time and temperature sensor readings. Fig. 4 is a flow chart showing a blood glucose concentration measuring method according to an embodiment of the present invention. Figure 5 shows a functional block diagram of a biochemical sensor in accordance with an embodiment of the present invention. [Main component symbol description] 100 biochemical test piece lla reference electrode lib working electrode 2 〇〇 biochemical sensor 201239358 211 reference electrode contact point 212 working electrode contact point 220 reference voltage source 230 current voltage conversion circuit 240 analog digital conversion circuit 250 processing 260 display 270 timer 280 temperature sensor 300 biochemical sensor 311 reference electrode contact point 312 working electrode contact point 320 reference voltage source 330 current voltage conversion circuit 340 analog digital conversion circuit 350 processor 360 display 370 timer 381 A temperature sensor 382 second temperature sensor 400 biochemical sensor