TW201200855A - Mixed test chip - Google Patents

Mixed test chip Download PDF

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Publication number
TW201200855A
TW201200855A TW099120881A TW99120881A TW201200855A TW 201200855 A TW201200855 A TW 201200855A TW 099120881 A TW099120881 A TW 099120881A TW 99120881 A TW99120881 A TW 99120881A TW 201200855 A TW201200855 A TW 201200855A
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TW
Taiwan
Prior art keywords
plate body
mixing
liquid
plate
test wafer
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TW099120881A
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Chinese (zh)
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TWI429894B (en
Inventor
Lung-Ming Fu
Hui-Hsiung Hou
Ruey-Jen Yang
Yao-Nan Wang
Ming-Chang Wu
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Univ Nat Pingtung Sci & Tech
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Priority to TW99120881A priority Critical patent/TWI429894B/en
Publication of TW201200855A publication Critical patent/TW201200855A/en
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Publication of TWI429894B publication Critical patent/TWI429894B/en

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Abstract

A mixed test chip includes a first board, a second board, and a third board. The first board has a plurality of the mixed paths and a plurality of the mixed openings. The opposite side of each mixed path communicates with two of those mixed openings. The mixed openings connect the opposite surface of the first board. The second board has a plurality of injecting openings is mounted in a surface of the first board. Each injecting opening communicates with each of the mixed path. The third board has a trough and a converging path is mounted in the other surface of the first board. One end of the converging path communicates with the trough; the other end of the converging path has a plurality of converging ends. The converging ends communicate with each mixed opening respectively. Consequently, promoting the mixed uniform of the fluids.

Description

201200855 六、發明說明: 【發明所屬之技術領域】 本發明係關於一種混合檢測晶片,特別是關於一種 可增加數種液體之混合效果,以提升檢測精確度之混合檢 測晶片。 【先前技術】 一般而言’傳統使用在數種液體混合之技術,主要 係將不同液體依序分別注入一容器内後,再透過震動或擾 拌等方式使該數種液體均勻混合,最後再取出部分之該均 勻混合的液體,藉此供特定實驗進行檢測作業或其他用途 。整體而言,由於該習知混合技術必須依序將不同液體分 別注入該容器内,以及必須再藉由額外方式使其均勻混合 ,因而導致該習知混合技術整體步驟過於繁鎖,造成使用 上產生諸多不便。 有鑑於此,睛參照第1圖所示,其揭示一種習知混 合檢測晶片9 ’其包含一基座91、一第一座體92及一第 二座體93。該基座91具有一儲存槽911 ;該第一座體92 係設置於該基座91上方,且該第一座體92之上表面設有 一混合區921及數個流道922,該數個流道922之一端係 分別連通該混合區921,另一端則分別形成一自由端923 ,且該混合區921係藉由一中心孔924與該儲存槽911相 連通;該第二座體93係設置於該第一座體92上方,且該 第二座體93設有數個注入孔931,各該注入孔931係分 別與該第一座體92之自由端923對位連通。藉此,當數 201200855 種液體分別經由該各該注入孔931注入後,即可分別經由 其所對應之自由端923流經各該流道922後,匯流至該混 合區921内進行混合,最後則再經由該中心孔924流進該 儲存槽911内’進而可方便完成液體混合作業。 然而’由於該數種液體匯流至該混合區921後,隨 即經由該中心孔924流至該儲存槽911内,因此該習知混 合檢測晶片9僅能進行單次的混合作業,如此一來,並無 法確保該數種液體混合的均勻度,進而嚴重影響後續檢測 作業的精確度。 基於上述原因,其確實有必要進一步改良上述習知 混合檢測晶片9。 【發明内容】 本發明目的係解決習知技術混合均勻度不佳之缺點 ,以提供一種方便數種液體進行混合作業之混合檢測晶片 ’並可有效達到提升液體混合均勻度的目的。 為達到前述發明目的,本發明所運用之技術手段及 藉由該技術手段所能達到之功效包含有: 一種此合檢測晶片,係包含:一第一板體,設有數 個混合流道及數個混合孔,各該混合流道之相對二端係分 別連通該混合孔之其中二個’該數偭混合孔係貫穿連通該 第-板體之相對二表面;-第二板體,設置於該第一板= 之一表面,該第二板體對應該混合流道之數量設有數個注 入孔,該數個注入孔係貫穿連通該第二板體之相對二表面 ,並分別與各該混合流道相連通;及一第三板體,設置於 201200855 該第一板體之另一表面,該第一板體被夾置於該第二板體 及第三板體之間,該第三板體設有一容液槽及一匯流道, 該匯流道之一端連通該容液槽,另一端則對應該混合孔之 數量形成有數個匯流端,且該數個匯流端分別與各該混合 孔相連通。 本發明係藉由預先分散數種液體之液量以進行第一 次液體混合作業,接著使分散混合之液體再進行第二次液 體混合作業’藉此利用少量多次的混合方式,有效達到提 升液體混合均勻度的功效。 【實施方式】 為讓本發明之上述及其他目的、特徵及優點能更明 顯易懂’下文特舉本發明之較佳實施例,並配合所附圖 式,作詳細說明如下: 請參照第2至4圖所示,本發明第一實施例之混合 檢測晶片係包含一第一板體1、一第二板體2及一第三板 體3,該第一板體1之相對二表面分別設有該第二板體2 及第三板體3,使該第一板體1被夾置於該第二板體2及 第二板體3之間;其中,該第一板體丨、第二板體2及第 三板體3較佳可選擇以玻璃材質、高分子材質或壓克力材 質製成,本實施例之數個板體皆選用價格低廉之聚甲基丙 烯曱醋(PMMA)製成’藉此方便且快速藉由雷射燒二方 式來分別完成各該板體上之微流道的製做,同時亦$有 降低製造成本。再者,各該板體之間較佳可選擇以螺人二 熱接合(thermal binding)或黏合等方式加以結合實 201200855 施例係選擇以熱接合方式將各該板體進行結合,藉此提供 -較佳之密賊果’㈣免雜㈣錢板體之間的縫隙 外洩。 該第一板體1设有數個混合流道丨〗及數個混合孔 ,該數個混合流道11係設置於該第一板體丨之上表面, 且各該混合流道11之相對二端係分別與該數個混合孔12 之其中二個相連通。該數個混合孔12係貫穿連通該第一 板體1之相對二表面。其中,連通於相同混合孔12之該 數個混合流道11,較佳#選擇連接於該混合孔12之切線 方向,且液體經由不同之該混合流道li流至該相同之混 合孔12的入液方向不位於同一直線上。藉此,當不同之 混合流道11内的液體流至相同之混合孔12内加以混合時 ’即可迫使該混合孔12内之混合液體產生自旋效應( self-rotation effect),進而可有效提升各該混合孔12内之 混合液體的混合均勻度。此外,該第一板體丨之厚度較佳 係選擇大於該數個混合孔12之直徑,亦即該數個混合孔 12之深度較佳係大於其自身之直徑,藉此延長該數個混 合孔12内之混合液體所產生自旋效應的混合作用時間, 以便進一步提升各該混合孔12内之混合液體的混合均勻 度。 該第二板體2對應該數個混合流道11之數量設有數 個注入孔21,且該數個注入孔21係貫穿連通該第二板體 2之相對二表面,並分別與各該混合流道u相連通。藉 此’當數種液體分別經由該不同之注入孔21注入後,即 可經由各該注入孔21所對應之混合流道11分流至不同之 201200855 ^合孔12内,以便各該混合孔12能夠將不同之液體加以 混合。在本實施例中,該數個混合孔21之數量係選擇為 二個做為實施樣態以利說明,亦即本發明係可提供兩種不 同液體進行混合作業。 本實施例之第三板體3係選擇包含一主板體31及一 田J板體32 ’該主板體31之相對二表面係分別與該第一板 體1及副板體32相連接◊該主板體31設有一容液槽3ιι 及一匯流道312,本實施例之容液槽311係選擇為貫穿該 主板體31之相對二表面的通孔,並分別藉由該第一板體 1及副板體32遮擋住該容液槽311之相對二侧,使該容 液槽311形成一密閉之容液空間A。其中,該第一板體i 對應於該容液槽311之位置較佳可設有—獅容液槽 13,且該輔助容液槽13較佳亦選擇為貫穿該第一板體^ 之相對二表面的通孔,藉此即可有效擴增該容液空間a 之大小。 該匯流$ 312係開設於該主板體31之上表面,且該 匯流道312係可選擇形成婉蜒曲折或直線延伸之流道,本 實施之匯流道312係選擇為直線延伸之流道。該匯流道 犯之-端係與該容液槽祀相連通,另一端則對應該數 個混合孔12之數量形成有數個隨端,且該數個匯 流端3121係分別與各該混合孔12對位連通。藉此,各該 混合孔12内之混合液體係能夠分別經由各該匯流端仙 流至該匯流道3U内後再次進行混合,並藉由該匯流道 312適當延長該數種液體的混合作用時間,雜流至該容 液空間A之混合液體的均勻度。 201200855 該副板體32 .之上表面設有一茂氣道32ι, 道 咖相連通,另—端則延咖 Γ,且該側表面較佳可選擇凹設形成有 、f ,該容液空間Α咖呈由該茂氣 ^ 保持與外界之間的連通狀態,使該容 ^間A内之氣體得以順利沿該茂氣道321及減槽似201200855 VI. Description of the Invention: [Technical Field] The present invention relates to a hybrid inspection wafer, and more particularly to a hybrid inspection wafer which can increase the mixing effect of several liquids to improve detection accuracy. [Prior Art] Generally speaking, the technology used in several kinds of liquid mixing is mainly to separately inject different liquids into a container, and then uniformly mix the liquids by vibration or scrambling, and finally A portion of the uniformly mixed liquid is withdrawn for testing or other uses for a particular experiment. In general, since the conventional mixing technique must sequentially inject different liquids into the container separately, and must be uniformly mixed by an additional method, the overall steps of the conventional mixing technique are too complicated, resulting in use. There are many inconveniences. In view of this, the eye is shown in Fig. 1, which discloses a conventional hybrid detecting wafer 9' which includes a susceptor 91, a first body 92 and a second body 93. The base 91 has a storage slot 911. The first base 92 is disposed above the base 91. The upper surface of the first base 92 is provided with a mixing zone 921 and a plurality of flow paths 922. One end of the flow channel 922 is respectively connected to the mixing zone 921, and the other end is respectively formed with a free end 923, and the mixing zone 921 is connected to the storage tank 911 through a central hole 924; the second seat body 93 is The second base body 93 is disposed above the first base body 92, and the second seat body 93 is provided with a plurality of injection holes 931, and each of the injection holes 931 is in an in-situ communication with the free end 923 of the first base body 92. Therefore, when the liquid of 201200855 is injected through each of the injection holes 931, respectively, it can flow through each of the flow passages 922 through the corresponding free ends 923, and then merge into the mixing zone 921 for mixing. Then, the liquid hole 924 flows into the storage tank 911 to further complete the liquid mixing operation. However, since the plurality of liquids flow into the mixing zone 921 and then flow into the storage tank 911 through the center hole 924, the conventional hybrid detecting wafer 9 can only perform a single mixing operation, and thus, It is not possible to ensure the uniformity of the mixing of the several liquids, thereby seriously affecting the accuracy of subsequent testing operations. For the above reasons, it is indeed necessary to further improve the above conventional hybrid detecting wafer 9. SUMMARY OF THE INVENTION The object of the present invention is to solve the disadvantages of poor mixing uniformity of the prior art, to provide a mixed detection wafer which facilitates mixing operations of several liquids, and can effectively achieve the purpose of improving liquid mixing uniformity. In order to achieve the foregoing object, the technical means and the achievable effects of the present invention include: A combined detection wafer comprising: a first plate body, a plurality of mixed flow channels and a plurality of a plurality of mixing holes, wherein the opposite ends of each of the mixing channels respectively communicate with two of the mixing holes, the plurality of mixing holes are connected to communicate with the opposite surfaces of the first plate; the second plate is disposed at The first plate=one surface, the second plate body is provided with a plurality of injection holes corresponding to the number of the mixed flow channels, and the plurality of injection holes are connected to the opposite surfaces of the second plate body, and respectively The mixed flow channel is connected to each other; and a third plate body is disposed on the other surface of the first plate body at 201200855, and the first plate body is sandwiched between the second plate body and the third plate body, the first The three-plate body is provided with a liquid-retaining tank and a collecting flow channel, one end of the connecting flow channel is connected to the liquid-retaining tank, and the other end is formed with a plurality of collecting ends corresponding to the number of mixing holes, and the plurality of collecting ends are respectively mixed with the respective mixing ends The holes are connected. The invention performs the first liquid mixing operation by pre-dispersing the liquid amount of several kinds of liquids, and then performing the second liquid mixing operation by dispersing the mixed liquids, thereby effectively achieving the lifting by using a small number of mixing modes. The effect of liquid mixing uniformity. The above and other objects, features and advantages of the present invention will become more <RTIgt; <RTIgt; </ RTI> <RTIgt; </ RTI> <RTIgt; </ RTI> <RTIgt; As shown in FIG. 4, the hybrid detecting chip of the first embodiment of the present invention comprises a first plate body 1, a second plate body 2 and a third plate body 3. The opposite surfaces of the first plate body 1 are respectively The second plate body 2 and the third plate body 3 are disposed such that the first plate body 1 is sandwiched between the second plate body 2 and the second plate body 3; wherein the first plate body is The second plate body 2 and the third plate body 3 are preferably made of glass material, polymer material or acrylic material. The plurality of plates of the embodiment are all made of low-cost polymethacrylic acid vinegar ( PMMA) is made to 'completely and quickly complete the micro-flow path on each plate by the laser burning method, and at the same time reduce the manufacturing cost. Furthermore, it is preferable that each of the plates is combined with a thermal bonding or bonding, etc. 201200855. The embodiment selectively combines the plates by thermal bonding, thereby providing - The better thief fruit '(4) free of miscellaneous (four) gap between the money board. The first plate body 1 is provided with a plurality of mixing channels and a plurality of mixing holes, and the plurality of mixing channels 11 are disposed on the upper surface of the first plate body, and the two opposite sides of the mixing channel 11 The end systems are in communication with two of the plurality of mixing holes 12, respectively. The plurality of mixing holes 12 extend through the opposite surfaces of the first plate body 1. The plurality of mixing channels 11 connected to the same mixing hole 12 are preferably connected to the tangential direction of the mixing hole 12, and the liquid flows to the same mixing hole 12 via the different mixing channels li. The liquid inlet directions are not on the same line. Thereby, when the liquid in the different mixing channels 11 flows into the same mixing hole 12 and is mixed, the mixture liquid in the mixing hole 12 can be forced to generate a self-rotation effect, thereby being effective. The mixing uniformity of the mixed liquid in each of the mixing holes 12 is increased. In addition, the thickness of the first plate body is preferably selected to be larger than the diameter of the plurality of mixing holes 12, that is, the depth of the plurality of mixing holes 12 is preferably greater than the diameter of the plurality of mixing holes 12, thereby extending the plurality of mixing. The mixing action time of the spin effect generated by the mixed liquid in the well 12 is to further increase the mixing uniformity of the mixed liquid in each of the mixing holes 12. The second plate body 2 is provided with a plurality of injection holes 21 corresponding to the number of the plurality of mixing channels 11, and the plurality of injection holes 21 are connected to the opposite surfaces of the second plate body 2, and are respectively mixed with the respective holes. The flow path u is connected. Therefore, when a plurality of liquids are respectively injected through the different injection holes 21, they can be branched into the different 201200855 holes 12 through the mixing channels 11 corresponding to the injection holes 21, so that the mixing holes 12 are respectively It is possible to mix different liquids. In the present embodiment, the number of the plurality of mixing holes 21 is selected as two as an embodiment, that is, the present invention can provide two different liquids for mixing. The third board body 3 of the embodiment is selected to include a main body body 31 and a first J body 32'. The opposite two surface systems of the main body 31 are respectively connected to the first board 1 and the sub board 32. The main body 31 is provided with a liquid-reserving tank 3 ιι and a manifold 312. The liquid-reserving tank 311 of the present embodiment is selected as a through-hole extending through the opposite surfaces of the main body 31, and is respectively provided by the first plate 1 and The auxiliary plate body 32 blocks the opposite sides of the liquid container 311, so that the liquid container 311 forms a sealed liquid space A. Preferably, the position of the first plate body i corresponding to the liquid container 311 is preferably provided with a lion tank 13 and the auxiliary liquid tank 13 is preferably selected to penetrate the first plate body. The through holes of the two surfaces can thereby effectively amplify the size of the liquid space a. The confluence $ 312 is formed on the upper surface of the main body 31, and the confluence channel 312 is selected to form a meandering or straight-line extending flow path. The confluence channel 312 of the present embodiment is selected as a straight extending flow path. The junction channel is connected to the liquid storage tank, and the other end is formed with a plurality of parallel ends corresponding to the number of the plurality of mixing holes 12, and the plurality of collecting ends 3121 are respectively associated with the mixing holes 12 Parallel connection. Thereby, the mixed liquid system in each of the mixing holes 12 can be mixed again through the respective confluent ends into the confluence channel 3U, and the mixing time of the plurality of liquids is appropriately extended by the confluence channel 312. , the uniformity of the mixed liquid mixed to the liquid space A. 201200855 The upper surface of the sub-board 32 is provided with a mooring channel 32ι, the road is connected, and the other end is extended, and the side surface is preferably formed with a recess, f, the liquid space The state of communication between the atmosphere and the outside is maintained, so that the gas in the chamber A can smoothly follow the mooring channel 321 and reduce the groove.

進而使該匯流道312内之液體能夠順利流至該容液 工曰内。其中,如各圖所示之洩氣道321 Ζ狀及位置僅為—綠朗之實施例,然其並不限制本Further, the liquid in the manifold 312 can be smoothly flowed into the liquid containing work chamber. Among them, as shown in the figures, the sluice channel 321 is shaped and the position is only the embodiment of the green ridge, but it does not limit the present.

發明僅為該减及位置者,其他可軸使該容液空間A 與外界互減if之轉設計,仍舰胁本發明之實施範 圍。 其中,本實施例之第一、第二、副板體i、2、32較 佳皆選擇為相同厚度之板體,而該主板體31之厚度較佳 則選擇大於該第一、第二、副板體1、2、32之厚度,藉 =相對擴增該容液空間A之容量,並可提升後續檢測作 業之精確度。 e凊參照第5 ®所示,本發明第—實施例之混合檢測 =片於進倾舰合作料,侧先將雜*同液體分別 、、士由各該&gt;主入孔21注入,使該二液體分別在各該混合流 11内如圖所示箭頭方向流動’藉此將該二液體分別分 散在各魏合流道U β,關後賴由少量多次的混合 方f進行液體混合作業。接著,該二液體則再分別經由各 合流道11匯流至各該混合孔12内進行混合,使各該 孔12内分別形成有一第一混合液,以完成第一次的 201200855 液體混合作業。 請參照第6圖所示,各該混合孔12内之第一混合液 係藉由自身所連通之匯流端3121流至該匯流道312内, 並如圖所示箭頭方向再次匯流進行混合形成一第二混合液 ,以完成第二次的液體混合作業;最後,藉由該匯流道 312適當延長該第二混合液的混合作用時間,使流至該容 液空間A内之第二混合液能夠具有極佳之混合效果,進 而順利完成具有極佳之混合均勻度的液體混合作業。 本發明之混合檢測晶片的技術特點在於:藉由預先 減少數種液體進行第一次液體混合作業之液量,以獲得數 個具有較佳混合均勻度之第一混合液,接著該數個第一混 合液則進行第二次液體混合作業再次混合形成該第二混合 液’如此’藉由少量多次的混合方式’可大幅提升該數種 液體的混合效果’使得本發明可有效達到提升液體混合均 勻度的功效。 睛參照第7及8圖所示,其揭示本發明第二實施例 之混合檢測晶片,相較於第一實施例,第二實施例之混合 檢測晶片同樣包含一第一板體1、一第二板體2及一第三 板體3’ ’該第一板體1及第二板體2與前述第一實施例 所揭示之結構特徵相同,於此不再贅述。 本實施例之第三板體3,亦選擇包含一主板體31,及一 副板體32’ ’該主板體31,設有一容液槽31Γ、一匯流道 312’及數個匯流端3121’,而該副板體32,則設有一洩氣道 321’及一洩氣槽322,;其中,該容液槽311,、匯流端 3121、洩氣道321’及洩氣槽322,係與前述第一實施例所 201200855 揭示之結構特徵相同,於此不再贅述。 相較於第一實施例’本實施例之匯流道312’係包含 數個主匯流道3122’、一辅助混合孔3123,及一次匯流道 3124’ ’該數個主匯流道3122,之一端係分別與各該匯流端 3121’相連通,另一端皆與該輔助混合孔3123,相連通;其 中,該數個主匯流道3122,較佳亦選擇連接於該輔助混合 孔3123’之切線方向,藉此使該輔助混合孔3123,内之混 合液體產生自旋效應,以便進一步提升第二次液體混合作 業之混合效果。該次匯流道3124,之相對二端分別連通該 輔助混合孔3123’及容液槽311’ ’且該次匯流道3124,與 該數假主匯流道3122’不位於同一平面上,藉此可有效延 長該辅助混合孔3123’之混合作用時間;再者,該次匯流 道3124’較佳可選擇為蜿蜒曲折之流道,進而可適當延長 該次匯流道3124’之混合作用時間。 本實施例於實際進行液體混合作業時,當各該混合 孔12完成第一次的液體混合作業後,係透過自身所連通 之匯流端3121’分別流至所對應之主匯流道3122,内,並 如第7圖所示箭頭方向再次匯流至該輔助混合孔3123,内 進行第二次的液體混合作業,最後則再流經該次匯流道 3124’流至該容液空間A内。藉此,本發明第二實施例之 混合檢測晶片,除了與第一實施例所述具有相同之作用與 效果外,該第二實施例更由於該輔助混合孔3123,之設計 ,更進一步提升第二次液體混合作業之混合效果,進而可 大幅提升液體的混合均勻度。 請參照第9圖所示,其揭示本發明第三實施例之混 201200855 二4 ’相較於第—實施例,第三實施例之混合檢測 4,該yt包含一第一板體1、一第二板體2及一第三板體 為二以板體1及第二板體2與前述第一實施例所揭示 之結構特徵相同,於此不再贅述。 相&amp;於第—實施例,本實施例之第三板體4係選擇 個板體所構成,該第三板體4設有—容液槽41、 ,二道42及—$氣道43 ’該容液槽41係選擇為貫穿 ' ·板體4之上表面的盲孔;該匯流道42之一端連通 ~今液槽41 ’另—端亦對應該數個混合孔12之數量形成 有數個匯&quot;|(_端42卜且該數個匯流端421分別與各該混合 孔12相連通,該錢道43之-端連通該容液槽4卜另 一端亦延伸第三板體4之—·槽… 藉此,本發明第三實施例之混合檢測晶片,除了與 第-實施觸述料相同之作賴效果外,料三實施例 更由於省略制板體32 ’而使其整體結構更為精簡。 雖然本發明已利用上述較佳實施例揭示,然其並非 用以蚊本發明’任何熟習此技藝者在不脫離本發明之精 神和範圍之内,相對上述實關進行各種絲與修改仍屬 本發明所㈣之技術料,因此本發明之保賴圍纽後 附之申請專利範圍所界定者為準。 —12 — 201200855 【圖式簡單說明】 第1圖 S知 &gt;邑合檢測晶片之立體分解圖。 第2圖 本發明第一實施例之立體分解圖。 第3圖 本發明第一實施例之組合圖。 第4圖 本發明第一實施例之上視圖。 第5圖 本發明第一實施例進行第一次液體混合作業 之示意圖。The invention is only for the reduction of the position, and the other axis can make the liquid space A and the outside world reduce the if design, and still implement the invention. Preferably, the first, second, and sub-boards i, 2, 32 of the embodiment are selected to be the same thickness of the board, and the thickness of the main body 31 is preferably greater than the first, second, and vice The thickness of the plate body 1, 2, 32, relative expansion of the capacity of the liquid space A, and can improve the accuracy of subsequent testing operations. Referring to FIG. 5, the hybrid detection of the first embodiment of the present invention is performed on the side of the dumping material, and the side is first injected with the liquid and the main inlet hole 21, respectively. The two liquids respectively flow in the direction of the arrow in the mixed flow 11 as shown in the figure, thereby dispersing the two liquids in the respective Wei-combination channels U β, and then performing the liquid mixing operation by a small number of mixing parties f. . Then, the two liquids are separately flowed into the mixing holes 12 through the respective mixing channels 11 to be mixed, and a first mixed liquid is formed in each of the holes 12 to complete the first 201200855 liquid mixing operation. Referring to FIG. 6 , the first mixed liquid in each of the mixing holes 12 flows into the bus passage 312 through the confluent end 3121 that is connected thereto, and is again merged and mixed in the direction of the arrow as shown to form a mixture. a second mixed liquid to complete the second liquid mixing operation; finally, the mixing time of the second mixed liquid is appropriately extended by the collecting passage 312, so that the second mixed liquid flowing into the liquid containing space A can be It has an excellent mixing effect, and smoothly completes the liquid mixing operation with excellent mixing uniformity. The technical feature of the hybrid detection wafer of the present invention is that the amount of liquid in the first liquid mixing operation is reduced by reducing a plurality of liquids in advance to obtain a plurality of first mixed liquids having better mixing uniformity, and then the plurality of A mixed liquid is subjected to a second liquid mixing operation and mixed again to form the second mixed liquid. Thus, the mixing effect of the plurality of liquids can be greatly improved by a small number of mixing modes, so that the present invention can effectively achieve the lifting liquid. The effect of mixing uniformity. Referring to Figures 7 and 8, the hybrid detecting wafer of the second embodiment of the present invention is disclosed. Compared with the first embodiment, the hybrid detecting wafer of the second embodiment also includes a first board 1 and a first The first plate body 1 and the second plate body 2' are identical to the first embodiment in the first embodiment, and will not be described again. The third board 3 of the embodiment is also selected to include a main body 31 and a sub-board 32'. The main body 31 is provided with a liquid reservoir 31, a manifold 312' and a plurality of converging ends 3121'. The sub-board 32 is provided with a deflation channel 321' and a deflation groove 322, wherein the liquid reservoir 311, the confluence end 3121, the deflation channel 321' and the deflation groove 322 are combined with the first implementation described above. The structural features disclosed in the example 201200855 are the same and will not be described again here. Compared with the first embodiment, the manifold 312' of the present embodiment includes a plurality of main manifolds 3122', an auxiliary mixing hole 3123, and a plurality of main channels 3124'. Each of the converging ends 3121' is in communication with each other, and the other end is connected to the auxiliary mixing hole 3123. The plurality of main channels 3122 are preferably connected to the tangential direction of the auxiliary mixing hole 3123'. Thereby, the mixed liquid in the auxiliary mixing hole 3123 is caused to have a spin effect to further enhance the mixing effect of the second liquid mixing operation. The opposite ends of the secondary flow channel 3124 are respectively connected to the auxiliary mixing hole 3123 ′ and the liquid receiving groove 311 ′′, and the secondary collecting channel 3124 is not in the same plane as the number of the false main collecting channels 3122 ′. The mixing time of the auxiliary mixing hole 3123' is effectively extended. Further, the secondary channel 3124' is preferably a meandering flow path, and the mixing time of the secondary channel 3124' can be appropriately extended. In the embodiment, when the liquid mixing operation is actually performed, after each of the mixing holes 12 completes the first liquid mixing operation, it flows through the confluent end 3121' connected to itself to the corresponding main collecting channel 3122. Then, the direction of the arrow shown in FIG. 7 is again merged into the auxiliary mixing hole 3123, and the second liquid mixing operation is performed, and finally, the secondary flow path 3124' flows into the liquid containing space A. Therefore, the hybrid detecting wafer of the second embodiment of the present invention has the same functions and effects as those described in the first embodiment, and the second embodiment is further improved by the design of the auxiliary mixing hole 3123. The mixing effect of the secondary liquid mixing operation can greatly improve the mixing uniformity of the liquid. Referring to FIG. 9, a hybrid detection 4 of a third embodiment of the third embodiment of the present invention is disclosed. The yt includes a first board 1 and a first embodiment. The second plate body 2 and the third plate body are two. The plate body 1 and the second plate body 2 are the same as those disclosed in the first embodiment, and will not be described again. In the first embodiment, the third plate body 4 of the present embodiment is formed by selecting a plate body, and the third plate body 4 is provided with a liquid receiving tank 41, two passages 42 and - $ air passage 43 ' The liquid reservoir 41 is selected as a blind hole penetrating through the upper surface of the plate body 4; one end of the bus channel 42 is connected to the current liquid channel 41', and the other end is also formed with a plurality of mixing holes 12 The _ end 42 and the plurality of converging ends 421 are respectively connected to the mixing holes 12, the end of the money channel 43 is connected to the liquid container 4, and the other end also extends the third plate body 4. - the tank... Thereby, the hybrid detecting wafer of the third embodiment of the present invention has the same overall effect as the first embodiment, except for the effect of the first embodiment. Although the present invention has been disclosed in the above-described preferred embodiments, it is not intended to be used in the present invention. Any skilled person can perform various kinds of yarns with respect to the above-mentioned aspects without departing from the spirit and scope of the present invention. Modification of the technical material still belonging to (4) of the present invention, and therefore the patent application scope attached to the warranty fence of the present invention 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 。 Fig. 4 is a top view of the first embodiment of the present invention. Fig. 5 is a schematic view showing the first liquid mixing operation of the first embodiment of the present invention.

第6圖:本發明第一實施例進行第二次液體混合作業 之示意圖。 第7圖:本發明第二實施例之立體分解圖。 第8圖:本發明第二實施例之上視圖。 第9圖:本發明第三實施例之立體分解圖。 【主要元件符號說明】 〔本發明〕 12 混合孔 31卜31Γ容液槽 3121、3121’ 匯流端 1 第一板體 11 混合流道 13 辅助容液槽 2 第二板體 21 注入孔 3、3’第三板體 31、31’主板體 312、312’匯流道 —13 — 201200855 3122’主匯流道 3124’次匯流道 321、32Γ洩氣道 4 第三板體 41 容液槽 421匯流端 44 洩氣槽 A 容液空間 3123’輔助混合孔 32、32’副板體 322、322’洩氣槽 42 匯流道 43 洩氣道 〔習用〕 9 習知混合檢測晶片 91 基座 911 儲存槽 92 第一座體 921 混合區 922 流道 923 自由端 924 中心孔 93 第二座 931 注入孔Fig. 6 is a view showing the second liquid mixing operation of the first embodiment of the present invention. Figure 7 is a perspective exploded view of a second embodiment of the present invention. Figure 8 is a top view of a second embodiment of the present invention. Figure 9 is a perspective exploded view of a third embodiment of the present invention. [Description of main component symbols] [Invention] 12 Mixing holes 31 卜 31 Γ tanks 3121, 3121' Confluence end 1 First plate 11 Mixed flow path 13 Auxiliary liquid tank 2 Second plate 21 Injection holes 3, 3 'Third plate body 31, 31' main body body 312, 312' confluence channel - 13 - 201200855 3122 'main manifold 3124' secondary manifold 321 , 32 Γ deflation channel 4 third plate 41 reservoir 421 confluence end 44 deflated Tank A reservoir space 3123' auxiliary mixing hole 32, 32' sub-plate body 322, 322' deflation groove 42 confluence channel 43 deflation channel [used] 9 conventional hybrid detection wafer 91 pedestal 911 storage tank 92 first body 921 Mixing zone 922 Flow path 923 Free end 924 Center hole 93 Second seat 931 Injection hole

Claims (1)

201200855 七、申請專利範園: 1、 一種混合檢測晶片,其包含: 一第一板體,設有數個滬合流道及數個混合孔,各該 混合流道之相對二端係分別連通該混合孔之其中二 個’該數個混合孔係貫穿連通該第一板體之相對二表 面; 一第二板體,設置於該第一板體之一表面,該第二板 體對應該混合流道之數量設有數個注入孔,該數個注 入孔係貫穿連通該第二板體之相對二表面,並分別與 各該混合流道相連通;及 一第三板體,設置於該第一板體之另一表面’該第一 板體被夾置於該第二板體及第三板體之間,該第三板 體設有一容液槽及一匯流道’該匯流道之一端連通該 容液槽’另一端則對應該混合孔之數量形成有數個匯 流端’且該數個匯流端分別與各該混合孔相連通。 2、 依申請專利範圍第1項所述之混合檢測晶片,其中該 匯流道係包含數個主匯流道、一輔助混合孔及一次匯 流道,該數個主匯流道之一端係分別與各該匯流端相 連通’另一端皆與該辅助混合孔相連通,該次匯流道 之相對二端則分別連通該辅助混合孔及容液槽。 3、 依申請專利範圍第2項所述之混合檢測晶片,其中該 數個主匯流道與該次匯流道係不位於同一平面上。 4、 依申請專利範圍第1、2或3項所述之混合檢測晶片, 其中該第三板體包含一主板體及一副板體,該主板體 —15 — 201200855 之相對一表面分別與該第一板體及副板體相連接,該 谷液槽係為貫穿該主板體之相對二表面的通孔,該匯 流道係設置於該主板體。 5、 依申請專利範圍第1、2或3項所述之混合檢測晶片, 其中該第三板體另設有一洩氣道,該洩氣道之一端連 通該容液槽,另一端貫穿該第三板體之一側表面。 6、 依申請專利範圍第5項所述之混合檢測晶片,其中該 第三板體之該側表面設有一洩氣槽’該洩氣槽係與該 洩氣道相連通。 7、 依申請專利範圍第1、2或3項所述之混合檢測晶片, 其中該混合流道係連接於該混合孔之切線方向,使液 體經由不同之混合流道流至相同之混合孔的方向不位 於同一直線上。 8、 依申請專利範圍第卜2或3項所述之混合檢測晶片, 其中該第一板體之厚度大於該混合孔之直徑。 9、 依申請專利範圍第卜2或3項所述之混合檢測晶片, 其中該第-板體設有-輔助容液槽,該輔助容液槽係 為貫穿該第-板體之相對二表面的通孔,並與該容液 槽對位連通。 i〇、tr專利範圍第卜2或3項所述之混合檢測晶片, 其中該匯流道係為婉埏曲折或直線延伸之流道。201200855 VII. Application for Patent Park: 1. A hybrid test wafer comprising: a first plate body having a plurality of Shanghai merge flow channels and a plurality of mixing holes, wherein the opposite ends of the mixed flow channels respectively communicate the mixture Two of the plurality of holes are connected to the opposite surfaces of the first plate; a second plate is disposed on a surface of the first plate, and the second plate corresponds to the mixed flow The number of the channels is provided with a plurality of injection holes, the plurality of injection holes are connected to the opposite surfaces of the second plate body, and are respectively connected to the mixed flow channels; and a third plate body is disposed at the first The other surface of the plate body is sandwiched between the second plate body and the third plate body. The third plate body is provided with a liquid receiving groove and a bus passage. The other end of the liquid reservoir is formed with a plurality of confluent ends corresponding to the number of mixing holes, and the plurality of confluent ends are respectively connected to the respective mixing holes. 2. The hybrid test wafer according to claim 1, wherein the manifold comprises a plurality of main manifolds, an auxiliary mixing hole and a primary manifold, and one of the plurality of main channels is respectively The other end of the confluent end is in communication with the auxiliary mixing hole, and the opposite ends of the secondary confluence channel respectively communicate with the auxiliary mixing hole and the liquid holding tank. 3. The hybrid test wafer of claim 2, wherein the plurality of main bus channels are not in the same plane as the bus bar system. 4. The hybrid test wafer according to claim 1, 2 or 3, wherein the third plate body comprises a main body and a sub-plate body, and the opposite surface of the main body -15 - 201200855 respectively The first plate body and the sub-plate body are connected to each other, and the valley liquid trough is a through hole penetrating through opposite surfaces of the main body, and the bus passage is disposed on the main body. 5. The hybrid test wafer according to the first, second or third aspect of the patent application, wherein the third plate body is further provided with a venting passage, one end of the venting passage is connected to the liquid receiving tank, and the other end is penetrated through the third plate. One side of the body. 6. The hybrid test wafer of claim 5, wherein the side surface of the third plate body is provided with a venting groove. The venting groove is in communication with the venting channel. 7. The hybrid test wafer of claim 1, 2 or 3, wherein the mixed flow channel is connected to a tangential direction of the mixing hole to allow liquid to flow through the different mixing channels to the same mixing hole. The directions are not on the same line. 8. The hybrid test wafer of claim 2, wherein the thickness of the first plate is greater than the diameter of the mixing hole. 9. The hybrid test wafer according to the second or third aspect of the patent application, wherein the first plate body is provided with an auxiliary liquid receiving tank, and the auxiliary liquid receiving tank is through the opposite surfaces of the first plate body. The through hole is in communication with the liquid reservoir. The hybrid test wafer of the above-mentioned item 2 or 3, wherein the bus passage is a meandering or straight-line extending flow path.
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TWI678534B (en) * 2015-09-29 2019-12-01 英屬開曼群島商鴻騰精密科技股份有限公司 Microfluidic device

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