TW201116825A - Bio-sensing device capable of automatically sensing sensing code and sensing method thereof - Google Patents

Abstract

The present invention relates to a bio-sensing device capable of automatically sensing a sensing code and a sensing method thereof, the bio-sensing device comprises: a bio-sensing strip and a process and display unit, the bio-sensing strip has a passive component, wherein a physical value of the passive component is able to present a sensing code; when the bio-sensing strip is inserted into the process and display unit, the process and display unit accesses the sensing code to produce an application compensation of a sample. Moreover, according to the sensing method, that is capable of controlling the process and display unit to sense the sensing code of the bio-sensing strip, and automatically, to access, calculate, compensate, and display the sensing code of the sample.

Description

201116825 VI. Description of the Invention: [Technical Field] The present invention relates to a biological sensing device, and more particularly to a passive component disposed on a biosensing cymbal such that a processing display unit can automatically detect the biological component A biosensing device capable of automatically detecting a sensing code and sensing method thereof, which is a sensing code of a test piece. [Prior Art] Due to the rapid development of sensor technology in recent years, various biosensors using enzyme redox reactions have been continuously proposed, and successively introduced new ones, among which biosensors in the field of biomedicine The most diverse types, such as blood glucose sensors, can be used to test blood sugar levels in blood. Therefore, blood glucose sensors have become an important device for self-testing of diabetic patients, which can help diabetics self-test the concentration of blood sugar in the body. It allows diabetics to pay attention to and control the blood glucose concentration in the body at any time to maintain the blood glucose concentration within the normal range. Once the patient finds that the body's blood glucose concentration is too high, it can be eaten, exercised, and injected with insulin. To control blood sugar levels, however, these controls must be approved by the doctor's supervision and advice. Please refer to the first and second figures as a perspective view of a conventional blood glucose sensing device and an exploded view of a conventional blood glucose sensing test piece, a conventional blood glucose sensing device 1 ', including: a blood glucose test piece丨2, and a processing display unit 10', wherein the blood glucose sensing test piece 12 comprises: a strip of 201116825 base plate 122', a reaction layer 124, a spacer 126, and a cover plate 128. An electrode portion 1221 is disposed at a front end of the strip substrate 122', and the reaction layer ι24, the spacer 126, and the cover plate 128' are disposed on the upper portion of the electrode portion 1221', and the electrode portion The operating electrode m2 is disposed on the upper surface of the strip substrate 122', and the first electrode 1226 is connected to the second electrode of the strip substrate 122'. 1228'. Further, the electrode layer 1221 is covered with an upper reaction layer 124' which has an enzyme enzyme to carry out an enzyme redox reaction. The diabetic patient uses the above-mentioned conventional blood glucose sensing device, and the %' first inserts the jk sugar sensing test piece 12 into the processing display unit ι, and then the patient must first test the blood glucose test piece 12 One of the sensing codes (stHp code) is input to the processing display unit 1〇, and then the blood of the body can be taken, and the gold liquid is directly dropped on the blood glucose sensing test piece 12, the reaction layer 1 24, above After a period of electrochemical reaction, the display unit 1 is processed. • The blood glucose concentration in the blood can be calculated by reading the current change generated by the electrochemical reaction. The conventional blood glucose sensing device 丨' is a relatively practical and accurate blood glucose sensing device. However, its biggest disadvantage is that the sensing code of the 5H blood glucose test strip 12 cannot be automatically detected. When the diabetic patient uses the conventional blood glucose sensing skirt 1, it is necessary to input the blood glucose sensing test piece 12 before the blood is dropped into the reaction layer 124, and the sensing code is used as the blood sugar concentration. However, once the patient enters the wrong sensing code, it will inevitably affect 201116825 to process the display unit.10, and calculate the accuracy of the blood glucose level 7 of the blood. In severe cases, the patient will be mistakenly judged for the condition of diabetes. A regrettable situation has occurred. Therefore, the inventor of the present invention has the disadvantages and disadvantages of the above-mentioned conventional sugar sensing device, and finally researches and develops the biosensing of an automatic price sensing code of the present invention. The main purpose of the device and its sense of content is to provide a bio-sensing split that can automatically detect the sensing code, and set a passive meta-sensing code on the bio-sensing test piece to make one The processing display unit can automatically obtain the sensing code by detecting the physical value of the cow, and can avoid that the processing display unit calculates an incorrect sample size because the user inputs an incorrect sensing code.

The main purpose of the present invention is to provide a sense of biosensing in order to make the processing display unit be able to automatically detect and detect the sensing sensor. Take and calculate 'compensation, and display accurate sample size. In order to achieve the main object of the present invention, the inventor of the present invention proposes a biosensing device capable of automatically detecting a sensing code, which comprises: a biological sensory test piece and a one-step processing method, which is not early. The biosensor test strip includes: a first electrode 'having an enzyme enzyme to react with a sample; a second [si 201116825 electrode having the enzyme enzyme to react with the sample; a passive component, The terminal is connected to the first electrode, the passive component has a physical value representative of the sensing code of the biosensor test strip, and a third electrode is connected to the other end of the passive 7C component to enable the passive component It can be electrically connected to an electronic circuit. The processing display unit includes: a detecting circuit electrically connected to the biometric test piece to detect the physical value of the passive component and converting the same into a first digital signal; a reading circuit, electrical property Connected to the biosensor test strip to read the electrochemical reaction signal and convert it into a second digital signal; a microprocessor electrically connected to the detection circuit and the buy circuit, the micro processing The device can confirm the sensing of the biosensor test piece by processing the first digital signal, and further set an appropriate compensation value, and the microprocessor can receive the second digital signal to process it into a sample: The measured value, initb, the microprocessor can compensate the value of the sample γ, _ value based on the appropriate compensation value to output an accurate sample magnitude; and a display electrically connected to the microprocessor To display the exact sample size. In order to achieve another object of the present invention, the inventor of the present invention proposes a sensing method of the j sensing device, which comprises the following steps: (1) inserting a biosensor test piece having a component into a processing display unit; a processing display unit activates one of its internal circuits; (3) the detection circuit detects a physical value of the passive component and converts it into a first digital signal; (4) - the microprocessor receives the first Digital signal to confirm the feeling. a sensor-sensing code; (5) the microprocessor further sets an appropriate compensation value by the sensing code 201116825; (,, J 钿 hip drops in the biosensor test piece - enzyme enzyme (7) a small early morning start one of its internal reading circuits; (8) the reading circuit reads the sample and the electrochemical reaction signal of one of the enzyme enzymes, and converts it into a second The digital signal microprocessor receives the second number. The file status 5 tiger and processes it as a sample measurement value, and (10) the microprocessor performs the sample measurement value based on the appropriate compensation value.仃 Numerical compensation to obtain and output accurate - sample magnitude. [Embodiment] In order to more clearly describe the bio-sensing skirt and its sensing of the present invention, which can automatically detect the sensing code The preferred embodiment of the present invention will be described in detail below with reference to the accompanying drawings. FIG. 1 is a structural diagram of a biosensing device capable of automatically detecting a sensing code according to the present invention, which can automatically detect The biosensing system of the sensing code includes a biological sensing test piece 11 and a processing display unit 丨 2 Please refer to the third figure and the fourth figure at the same time, wherein the fourth figure is a top view of the biosensor test piece, and the biosensor test piece 包括i includes: a first electrode 111 ′ is electrically connected to the process An electronic circuit '3' inside the display unit 12 has an enzyme-enzyme 1111 that can react with a sample 2, and an electrode ii 2 can be electrically connected to the inner electronic circuit of the display unit i 2 . 4, the second electrode 112 has the enzyme enzyme η" to react with the sample 2; - the passive element 113 is connected at one end thereof to the first electrode 111', and the passive element 丨丨3 has a physical value representing a biological sense 201116825 The test piece 11 is a sensing code, wherein the passive component U3 can be a resistor, a capacitor or an inductor; and the third electrode 114 is connected to the other end of the passive component 113, so that the passive component 113 can be electrically In the present embodiment, the first electrode lu is used as a _ working electrode (the electrode is called electrode), and the second electrode 112 is a counter electrode corresponding to the working electrode; Electrode 114 acts as a passive component 1 The sensing display unit 12 includes a detecting circuit 121 electrically connected to the biosensor test piece. The physical value of the passive component 丨13 is detected and converted into a first digital signal; the read circuit 122 is electrically connected to the biosensor test piece u to the sample 2 and the enzyme enzyme The electrochemical reaction signal of the llu is read and converted into a second digital signal; a microprocessor 123 is electrically connected to the debt measuring circuit 121 and the reading circuit 122, and the microprocessor 123 can By processing the first-digit signal, the sensing code of the bio-sensing test piece is confirmed and a suitable compensation value is further set, and the microprocessor 123 can receive the second-digit signal and process it into a sample amount. In addition, the microprocessor U3 can perform numerical compensation on the sample measurement value based on the appropriate compensation value to output an accurate sample magnitude; and a display 124 electrically connected to the microprocessor The device 123 displays the sample magnitude, and the display (3) can be - An LCD display or a coffee display, preferably this embodiment uses a haihai LCD display as a display for processing the display unit u

SI 9 201116825 124. Please continue to refer to FIG. 5, which is the first circuit structure diagram of the detection circuit. The detection circuit m of the processing display unit 12 has two circuit architectures for detecting different passive components 13 respectively. Physical value. As shown in the fifth figure, when the passive component 113 is the sense code resistor Rc, the detection circuit 1 2 1 detects the physical value of the sense code resistor rc, that is, a resistance value RP (RP is a formula) The detecting circuit 121 includes a second operational amplifier 1216, a conversion resistor Rf and a second analog digital converter 121A. The second operational amplifier 1216 has a second amplifier negative input terminal 1217, a second amplifier positive input terminal 1218, and a second amplifier output terminal 1219. The second operational amplifier 1216 can convert the physical value of the passive component 113 into a The first voltage signal has a first voltage value added to the formula using a symbol instead of a component symbol; the conversion resistor Rf is coupled to the second amplifier negative input terminal 1217 and the The 'conversion resistor Rf between the second amplifier output terminal 1219 can assist in converting the physical value of the passive component U3 into a first voltage signal; and the second analog-to-digital converter 121A is coupled to the second amplifier output terminal 1219 to receive the first A voltage signal is converted to the first digital signal. Since the positive input terminal 1218 of the second amplifier is connected to a third reference voltage Vref3, the resistance value Rp can be calculated by calculating the formula: Rp=(Vref3XRf) / (Vout_Vref3), and the resistance value Rp can be used. To represent the sensing code.

SI 10 201116825 凊 Also refer to the sixth figure, which is a second circuit architecture diagram of the detection circuit. If the 忒 passive component π 3 is not the sensing code resistor Rc but a sensing code capacitor Cc, the detection circuit 121, the physical value of the sensing code capacitor Cc must be detected, that is, a capacitance value Cp (Cp is a symbol of the formula), wherein the detecting circuit 121 for detecting the capacitance value Cp includes: A current source 1210, a comparator 1211, and a counter 1215. The current source 12 10 can charge the sensing code capacitor cc to generate a charging voltage vc 0 for the formula using a symbol instead of a component symbol; the comparator 包括2丨 includes a positive input of the vehicle 1212, a comparator negative input terminal 12丨3, and a comparator output terminal 1214, wherein the comparator negative input terminal 1213 is coupled to a second reference voltage Vref2, and the comparator positive input terminal 1212 is coupled The comparator 12b can compare the charging voltage Vc with the second reference voltage Vref2. When the value of the charging voltage 〇 is higher than the second reference voltage Vref2, the comparator 1211 outputs a high level signal; the _ counter 1 2 1 5 is coupled to the microprocessor} 23, the comparator 1211, and a sensing code 3, please also refer to the seventh picture, which is a sensing code The charging timing diagram, when the start signal (sensing c〇de) 3 is set to the high level, the current source 12 1〇 charges the sensing code capacitor cc, and the counter 1 21 5 starts counting until the comparison After the timer 1 2 11 outputs the high level signal to the counter 1215, the counter 1 215 stops counting and records a count value N (N is the formula using the symbol). As shown in the seventh figure, a curve A and a curve b respectively represent the charging voltage Vc of the capacitance Cc with the sensing code 201116825 of different capacitance values Cp; - Ts is the starting time of the counter i2i5 to start counting; - TenA ^ TenB denotes the day-to-day interval of the counter 2 1 5 stop number respectively, a cl〇ck-^ indicates the input clock signal; a Tclk is the one cycle time of the input clock signal; and, one (3) and eight A codeB is the output of the comparator 1211 after receiving the curve a and the charging voltage Vc of the curve 8 and then comparing with the second reference voltage Vref2, wherein the codeA is converted to a high level signal at the TenA. And the codeB is converted to a high level signal at the D6113; in addition, a clock_〇utA and a ci〇ck_outB indicate that the counter 1215 outputs a signal to the microprocessor 123, and the microprocessor can use the ci 〇ck_〇utA and the clock_outB calculate the count value N of the charging time of the curve A and the curve B. Since the value of the charging voltage Vc is the current value of one of the current sources i2i, (Ic is the formula using the symbol instead of the component symbol) and the charging time of the sensing code capacitor Cc is divided by the capacitance value Cp, therefore, the calculation formula is transmitted. :Cp =(NXTclkXIc) /Vc, the capacitance value & capacitance value cp can be calculated to represent the sensing code. Please refer to FIG. 8 again, which is a structural diagram of the read circuit. The read circuit 122 included in the microprocessor 123 includes a first operational amplifier 1220, an input resistor Ri, and an amplification resistor Ra. And a first analog digital converter 1226. The first operational amplifier i22 has a first amplifier positive input terminal 1221, a first amplifier negative input terminal 1 222, and a first amplifier output terminal 1223, wherein the first amplification

I SI 12 201116825, the positive input terminal 1221 is coupled to a first reference voltage Vrefi, the first operational amplifier 1220 can read the electrochemical reaction signal and convert it into a second voltage signal; the input resistance Ri coupled Connected to the first amplifier negative input terminal 1222 to serve as the first catch | the crying & ^ delay differential device 1220 input buffer resistor; the amplification resistor Ra is connected to the 坌 -, the Ding handle according to the younger brother to enlarge Steal the wheel 1222 and the first amplifier output! Between 223, an amplification resistor to assist in amplifying the output gain of the first operational amplifier 1220; the first analog digital converter I]%

Receiving the second voltage, the two voltage signals are converted to be connected to the first operational amplifier output 1223. The first analog digital converter 1226 can transmit the second digital signal. Thereafter, the microprocessor 123 can receive the second digit table number to make the value of the sample into the sample measurement value, and then appropriately compensate the sample measurement value, and then display by the display 124. The size of the specimen is selected. The above has been quite complete for the preferred embodiment (4). In addition, the bio-sensing device i for automatically detecting the sensing code can be controlled to complete the sensing and sensing of the sample 2. The method of sensing the biological money device will be fully disclosed in the following descriptions. Please also refer to the flow chart of the sensing method of the first and second small biosensing devices. The sense "method" includes the following steps: First, the step (201) is performed, and the biometric test piece having the passive component ιΐ3 is processed by the display unit 12; then, the processing is performed by ^ 13 t si 201116825 , ) Not only 兀1 2 activates the internal detection circuit 丨2 1 ; 7 performs the step (2G3) 'detection circuit 121 detects the passive component 113 ^ value and converts it into the first digital signal; then executes ν ( 04) and step (205), the microprocessor 123 receives the first digital signal ' to confirm the sensing code of the biosensor test piece 11, and the microprocessor 123 sets the signal by using the sensing code. Appropriate compensation value; after learning the sensing code, you can start The subject 2 perform sensing and inspection steps performed ten

Step (2〇6) 'The sample 2 drops the human enzyme test u to the enzyme enzyme uu orbit step (207), and the processing display unit 12 activates its internal helium feed circuit 122; and then performs the steps ( 2〇8), reading the circuit ID, reading the electrochemical reaction signal of the sample 2 and the enzyme enzyme "u, and converting it into 4th-digit signal; then, performing the step (s), the microprocessor 1 receiving the _th digital message 5 tiger and processing it as the sample measurement value; and executing step (210), the microprocessor 123 performs numerical compensation on the sample measurement value based on the appropriate compensation value to obtain And output accurate sample magnitude. The step (203) is a step of measuring the physical value of the passive component "3; however, if the passive component 113 is the sensing code resistor Rc', the detection circuit 121 must be used. The first circuit architecture is to read the resistance value Rp of the sensing code resistor Rc. Please refer to the tenth figure, the first detailed step flow chart of the step (203), and the step (2〇3) includes the following detailed steps:

[SI 14 201116825 First, the step (2G31) is executed, the second operational amplifier i2i3 receives the physical value of the passive component (1) and converts it into the first electrical signal; and, performs the step (2〇32) The second analog-to-digital converter 1217 receives the first voltage signal and converts it into the first digital signal. If the passive component is used as the sensing code capacitor cc by the 113th of the detecting circuit 12 1 , the two circuit architecture must be used to read the charging voltage Vc of the sensing code capacitor Cc to make the microprocessor 123 can be calculated continuously

6H electricity valley Cp, please refer to the eleventh figure, the second detailed step flow chart of step (2〇3) 'The above steps (2()3) include the following second detailed steps: Step (203,), the startup signal is set to a high level to activate the current source 1210 and the counter 1215; then, step (2032) is performed, and the current source 121 充电 charges the passive component U3. That is, the sensing code capacitor Cc is caused to generate the charging voltage Vc; then, step (2033,) is performed, the comparator 1211 simultaneously receives the charging voltage... and the second reference voltage Vef2; and then performs the step (2) 34,), the comparator an determines whether the charging voltage Vc is higher than the second reference voltage Vef2, and if so, proceeds to step (2035,) and the step (2〇36,), the comparator mi outputs a high level signal to the The counter 1215, then, the counter i2i5 stops counting and records a count value N; and, by performing the step (2〇37,), the number 1 1 1 5 5 outputs the first digit signal; in addition, in the step (2〇34) ,), if no, continue with the steps (2033 ), I.e., following the comparators 12u 15201116825 continuously receiving a charging voltage and a second reference voltage ^ vef2. Finally, referring to the twelfth figure, the detailed steps of step (208) are the steps of step (2〇8) for reading the electrochemical reaction, and the step (208) includes the following detailed steps. First, performing step (2081), the first operational amplifier 122 receives the electrochemical reaction signal and converts it into the second voltage signal; and 'execution step (2082), the first analog-to-digital converter receives The second voltage m number, the ju word, is converted into the second digital signal. The above is a complete and clear disclosure of a biosensing device capable of automatically detecting a sensing code of the present invention and a method for sensing the same. Therefore, in summary, the present invention has the following advantages: 1. Invented to set the passive component on the biosensor test strip and add the stripping circuit to the processing display unit to test the physical value of the passive component to automatically obtain the sensing code and calculate the value for the The sample measurement value performs numerical compensation, so that the user (diabetic patient) inputs an incorrect sensory code, and the processing display unit calculates the wrong sample size. 2. The sensing method of the far bio-sensing device can automatically cause the processing display unit to automatically sense the sensing code of the bio-sensing test piece, and read, count, compensate, and display an accurate sample amount. value. However, the above detailed description is directed to the specific embodiments of the present invention in the context of the present invention, but the embodiment is not intended to limit the scope of the patent of the present invention, where 16 201116825

Equivalent implementations or variations that do not depart from the spirit of the invention are within the scope of the invention. 〜L包含 [Simple description of the diagram] The first diagram, the second diagram, the third diagram, the stereoscopic diagram of the conventional blood glucose sensing device. The decomposition diagram of the conventional blood glucose sensation test piece. Automatically detecting the sensing code. &gt; ', <Architecture diagram of the biological sensing device; The fourth picture is a top view of the biological sensing test piece of the biological sensing device capable of automatically detecting the sensing code; The first circuit structure diagram of the biometric sensing device of the sensing code is measured; the sixth circuit is the second circuit architecture diagram of the detecting circuit; the seventh figure is the biological sensing capable of automatically detecting the sensing code Device--the charging timing diagram of the sensing code capacitor; the eighth picture is the bio-sensing device that can automatically detect the sensing code--the structure diagram of the reading circuit; the ninth picture is a sensing method of the biological sensing device The tenth diagram is the first step of the step (203) - the detailed step flow chart; the eleventh figure is the second detailed step flow chart of the step (203); and the twelfth step is the detailed step flow of the step (208) Figure. 201116825 % [Explanation of main component symbols] 1 Biosensing device capable of automatically detecting the sensing code 1 5 Conventional blood glucose sensing device 10' Processing display unit 11 Biosensor test piece 111 First electrode 1111 Enzyme enzyme # 112 Second Electrode 114 Third electrode 12 Processing display unit 12, blood glucose sensing test piece 121 Detection circuit 1210 Current source 1211 Comparator Φ 1212 Comparator positive input terminal 1213 Comparator negative input terminal 1214 Comparator output terminal 1215 Counter 1216 Second operational amplifier 1217 Second amplifier negative input 1218 Second amplifier positive input 1219 Second amplifier output 201116825

121 A first analog-to-digital converter 122 read circuit 1225 strip substrate 1220 first operational amplifier 1221 first amplifier positive input terminal 122Γ electrode portion 1222 first amplifier negative input terminal 1222' operation electrode 1223 first amplifier output terminal 12245 corresponding Electrode 1226 first analog digital converter 1226, first lead 1228, second lead 123 microprocessor 124 display 1245 reaction layer 1265 spacer 1285 cover 2 sample 201~210 method steps 203 1 ~ 2032 method step 203 1 ' 〜20375 Method Step 19 201116825 208 1~2082 Method Step 3 Start Signal Cc Sense Code Capacitor Cp Capacitance Value Ic Current Value N Count Value Ra Amplifier Resistor Rc Sense Code Resistor Rf Conversion Resistor Ri Input Resistor Vc Charging Voltage Vout First Voltage Value Vref1 First Reference Voltage Vref2 Second Reference Voltage Vref3 Third Reference Voltage 20

Claims (1)

201116825 VII. The scope of patent application: 丨 _ - Kind: Automatic sensing device for biological sensing, including: Biosensor test piece 'The biosensor test piece includes: - the first electrode' system, electrically connectable An electronic circuit, the first electrode having an enzyme enzyme reactive with the sample; the second electrode being electrically connectable to the electronic circuit, the first electrode having the enzyme enzyme reactive with the sample; The passive tether is connected to the first electrode at one end thereof, the passive component has a physical value representing one of the sensing chips of the biosensor test piece; and a third electrode is connected to the other end of the passive component to enable passive The component can be electrically connected to the electronic circuit; and the processing display unit is configured to digitize the electrochemical reaction signal of the sample and the enzyme enzyme. The processing display unit comprises: a detecting circuit electrically connected to the biological sense The test piece measures the physical value of the passive component and converts it into a first digital signal; a reading circuit electrically connected to the biological sensing test piece to electrify the sample and the enzyme enzyme The reaction signal is read out and converted into a second digital signal; a microprocessor is electrically connected to the detecting circuit and the reading circuit, and the microprocessor can process the first digital signal 21 On 201116825, it is confirmed that the bio-salt test continues y + 4, the sensing code of the 4 state bin film, and further sets the value of the Biantian fill 4, and the microprocessor can receive the second digital signal and process it as - the measured value of the sample, in addition, the microprocessor can perform numerical compensation on the measured value of the sample based on the appropriate compensation value of 咭诵A 4 ice and IP shoulder, so as to obtain an accurate amount of the sample Value; and A display is electrically coupled to the microprocessor to display an accurate magnitude of the sample. 2. The bio-sensing device capable of automatic reconnaissance measurement, as described in claim 4, wherein the first electrode is a working electrode, and the second electrode is opposite to one of the working electrodes. An electrode, the third electrode acts as a sensing code electrode connecting one of the passive components. 3 ‘A biosensing device capable of automatically extracting a sensing code as described in claim 1 of the patent application scope, wherein the sample is blood. 4. A biosensing device as described in claim 1 of the invention, wherein the passive component can be any of the following capacitors and inductors. 5. The biological sensing splitting of the sensor can be automatically detected as described in claim 1 wherein the display can be any of the following: an LCC display and an LED display. An automatic detectable sensing device according to the invention of claim 1, wherein the read circuit further comprises: 22 6. 201116825 A first operational amplifier having a first amplifier An input terminal, a first amplifier negative input terminal, and a first amplifier output terminal, wherein the first amplifier positive input terminal is coupled to a first reference voltage, and the first operational amplifier can read the electrochemical reaction signal And converting the input to a second voltage signal; the input resistor is coupled to the negative input of the first amplifier to serve as an input buffer resistor of the first operational amplifier; An amplification resistor is coupled between the negative input terminal of the first amplifier and the output end of the first amplifier, the amplification resistor can assist in amplifying the output gain of the _ operational amplifier; and the first analog digital converter is coupled to the first The operational amplifier output receives the second voltage signal, and the first analog digital converter converts the second voltage signal into the second digital signal. For example, the bio-sensing device of the automatic (four) sensing code described in claim 6 of the patent, wherein the detecting circuit further comprises: a second operational amplifier having a second amplifier negative input a first amplifier, a second amplifier output, and a second amplifier output, the first amplifier can convert the physical value of the passive component into a first voltage signal; a conversion resistor is coupled to the second amplifier Between the negative input terminal and the first amplification device, the conversion resistor can assist in converting the passive physical value of the cow into the first voltage signal; and 23 201116825 the first analog digital converter is coupled to the second amplifier The output terminal receives the first voltage signal and converts it into the first digital signal. 8. The biosensing device capable of automatically detecting a sensing code according to claim 6, wherein the detecting circuit further comprises: a current source, wherein the current source can charge the passive component, so that The comparator generates a comparator positive input terminal, a comparator negative input terminal, and a comparator output terminal, wherein the comparator negative input terminal is coupled to a second reference voltage. Moreover, the positive input terminal of the comparator is connected to the passive component. The comparator can compare the charging voltage with the second reference voltage. When the value of the charging voltage is higher than the second reference voltage, the comparator outputs a a high level signal; and a counter 'coupled to the microprocessor, the comparator, and a start signal'. When the start signal is set to a high level, the current source charges the passive component, and the counter starts. After counting, until the comparator outputs the high level signal to the counter, the counter stops counting and records a count value. 9. A sensing method of a biosensing device, comprising: (1) inserting a biosensor test piece having a passive component into a processing display unit; (2) processing the display unit to activate one of the internal detecting circuits CSI 24 201116825 (3) The detection circuit detects a physical value of the passive component and converts it into a first digital signal; (4) a microprocessor receives the first digital signal to confirm the biological a sensing code of one of the test pieces; (5) the microprocessor further sets an appropriate compensation value by the sensing code; (6) a sample is dropped on the enzyme enzyme of one of the biological test pieces ® (7) The processing display unit activates one of its internal read circuits; (8) The read circuit reads the sample and the enzyme-electrochemical reaction signal and converts it into a second a digital signal; (9) the microprocessor receives the second digit signal and processes it as a sample measurement value; and (10) the microprocessor performs numerical compensation on the sample measurement value based on the appropriate compensation value 'To get and output accurate - sample size. The sensing method of a bio-sensing device according to claim 9, wherein the step (3) further comprises: (31) - the second operational amplifier receives the physical value of the passive component And converting it into a first voltage signal; and (32) - the second analog digital converter receives the first voltage signal and converts it into the first digital signal. U. The method for measuring a biosensing device according to claim 9 wherein the step (8) further comprises: I S1 25 201116825 (81) - the first operational amplifier receives the electrochemical reaction signal And converting it into a second voltage signal; and C 82 ) - the first analog digital converter receives the second voltage signal and converts it into the second digital signal. 12. The sensing method of a biosensing device as described in claim 9 of the patent application, wherein the step (3) further comprises: (3 1 ) setting a start signal to a high level to start a current source # and - counter; (32) 戎 current source charges the passive component to generate a charging voltage; the comparator simultaneously receives the charging voltage and a second reference voltage; 34 ° Hai comparator determines whether the charging voltage Step (35) is performed above the second reference voltage 'if yes', and step (33) is performed if not; 35) the comparator outputs a high level signal to the counter; 36) the counter stops counting and records one Count value; and 3 7) The leaf number device outputs the first digit signal. 26