TW201041867A - Piperidin-pyrimidine derivatives as histamine H4 receptor antagonists - Google Patents

Piperidin-pyrimidine derivatives as histamine H4 receptor antagonists Download PDF

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Publication number
TW201041867A
TW201041867A TW099104788A TW99104788A TW201041867A TW 201041867 A TW201041867 A TW 201041867A TW 099104788 A TW099104788 A TW 099104788A TW 99104788 A TW99104788 A TW 99104788A TW 201041867 A TW201041867 A TW 201041867A
Authority
TW
Taiwan
Prior art keywords
alkyl
group
compound
formula
halogen
Prior art date
Application number
TW099104788A
Other languages
English (en)
Chinese (zh)
Inventor
Gonzalez Elena Carceller
Fuentes Eva Maria Medina
Garcia Ana Morato
Costa Carles Ferrer
Original Assignee
Palau Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palau Pharma Sa filed Critical Palau Pharma Sa
Publication of TW201041867A publication Critical patent/TW201041867A/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW099104788A 2009-02-18 2010-02-12 Piperidin-pyrimidine derivatives as histamine H4 receptor antagonists TW201041867A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09382022 2009-02-18
US17335409P 2009-04-28 2009-04-28

Publications (1)

Publication Number Publication Date
TW201041867A true TW201041867A (en) 2010-12-01

Family

ID=40912138

Family Applications (1)

Application Number Title Priority Date Filing Date
TW099104788A TW201041867A (en) 2009-02-18 2010-02-12 Piperidin-pyrimidine derivatives as histamine H4 receptor antagonists

Country Status (3)

Country Link
AR (1) AR075514A1 (fr)
TW (1) TW201041867A (fr)
WO (1) WO2010094721A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX346667B (es) * 2010-10-07 2017-03-28 Bayer Cropscience Ag * Composicion fungicida que comprende derivado de tetrazoliloxima y derivado de tiazolilpiperidina.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7985745B2 (en) * 2006-10-02 2011-07-26 Abbott Laboratories Method for pain treatment

Also Published As

Publication number Publication date
AR075514A1 (es) 2011-04-06
WO2010094721A1 (fr) 2010-08-26

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