TW200902034A - Effective treatment of tumors and cancer with prodrugs of triciribine - Google Patents

Effective treatment of tumors and cancer with prodrugs of triciribine Download PDF

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Publication number
TW200902034A
TW200902034A TW097111304A TW97111304A TW200902034A TW 200902034 A TW200902034 A TW 200902034A TW 097111304 A TW097111304 A TW 097111304A TW 97111304 A TW97111304 A TW 97111304A TW 200902034 A TW200902034 A TW 200902034A
Authority
TW
Taiwan
Prior art keywords
cancer
akt
tcn
cell
tumor
Prior art date
Application number
TW097111304A
Other languages
English (en)
Chinese (zh)
Inventor
Lawrence Akinsanmi
Original Assignee
Vioquest Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vioquest Pharmaceuticals Inc filed Critical Vioquest Pharmaceuticals Inc
Publication of TW200902034A publication Critical patent/TW200902034A/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW097111304A 2007-03-28 2008-03-28 Effective treatment of tumors and cancer with prodrugs of triciribine TW200902034A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90730507P 2007-03-28 2007-03-28

Publications (1)

Publication Number Publication Date
TW200902034A true TW200902034A (en) 2009-01-16

Family

ID=39712321

Family Applications (1)

Application Number Title Priority Date Filing Date
TW097111304A TW200902034A (en) 2007-03-28 2008-03-28 Effective treatment of tumors and cancer with prodrugs of triciribine

Country Status (2)

Country Link
TW (1) TW200902034A (fr)
WO (1) WO2008121261A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI781960B (zh) * 2016-10-03 2022-11-01 美商阿克思生物科學有限公司 腺核苷5'-核苷酸酶之抑制劑及相關用途

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2841075T (pt) * 2012-04-26 2020-06-25 Massachusetts Gen Hospital Agentes e métodos para tratamento e prevenção de queratose seborreica
US10508309B2 (en) 2013-05-17 2019-12-17 The General Hospital Corporation Methods for detecting and treating variants of seborrheic keratoses
US20220395575A1 (en) * 2019-11-14 2022-12-15 H. Lee Moffitt Cancer Center And Research Institute, Inc. Combination therapy with protein kinase b activation inhibitor to treat cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123524A (en) * 1977-06-08 1978-10-31 The United States Of America As Represented By The Department Of Health, Education And Welfare Synthesis of 6-amino-4-methyl-8-(β-D-ribofuranosyl)pyrrolo[4,3,2-de]pyrimido[4,5-C]pyridazine-5'-phosphate as a novel compound and its utility against L-1210 mouse leukemia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI781960B (zh) * 2016-10-03 2022-11-01 美商阿克思生物科學有限公司 腺核苷5'-核苷酸酶之抑制劑及相關用途

Also Published As

Publication number Publication date
WO2008121261A3 (fr) 2008-12-24
WO2008121261A2 (fr) 2008-10-09

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