TW200825414A - Biomarker molecule of gastrointestinal disease and measurement method thereof - Google Patents

Biomarker molecule of gastrointestinal disease and measurement method thereof Download PDF

Info

Publication number
TW200825414A
TW200825414A TW095145918A TW95145918A TW200825414A TW 200825414 A TW200825414 A TW 200825414A TW 095145918 A TW095145918 A TW 095145918A TW 95145918 A TW95145918 A TW 95145918A TW 200825414 A TW200825414 A TW 200825414A
Authority
TW
Taiwan
Prior art keywords
groes
acid sequence
derivative
amino acid
sequence
Prior art date
Application number
TW095145918A
Other languages
English (en)
Chinese (zh)
Other versions
TWI317811B (OSRAM
Inventor
Lu-Ping Chow
Yu-Fen Lin
Jaw-Town Lin
Ming-Shiang Wu
Original Assignee
Univ Nat Taiwan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nat Taiwan filed Critical Univ Nat Taiwan
Priority to TW095145918A priority Critical patent/TW200825414A/zh
Priority to US11/698,820 priority patent/US20080138806A1/en
Publication of TW200825414A publication Critical patent/TW200825414A/zh
Priority to US12/230,585 priority patent/US20090170100A1/en
Application granted granted Critical
Publication of TWI317811B publication Critical patent/TWI317811B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5753—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the stomach or small intestine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/205—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
TW095145918A 2006-12-08 2006-12-08 Biomarker molecule of gastrointestinal disease and measurement method thereof TW200825414A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
TW095145918A TW200825414A (en) 2006-12-08 2006-12-08 Biomarker molecule of gastrointestinal disease and measurement method thereof
US11/698,820 US20080138806A1 (en) 2006-12-08 2007-01-29 Biomarkers and detection methods for gastric diseases
US12/230,585 US20090170100A1 (en) 2006-12-08 2008-09-02 Biomarkers and detection methods for gastric diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW095145918A TW200825414A (en) 2006-12-08 2006-12-08 Biomarker molecule of gastrointestinal disease and measurement method thereof

Publications (2)

Publication Number Publication Date
TW200825414A true TW200825414A (en) 2008-06-16
TWI317811B TWI317811B (OSRAM) 2009-12-01

Family

ID=39498520

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095145918A TW200825414A (en) 2006-12-08 2006-12-08 Biomarker molecule of gastrointestinal disease and measurement method thereof

Country Status (2)

Country Link
US (2) US20080138806A1 (OSRAM)
TW (1) TW200825414A (OSRAM)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
WO2007081385A2 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
EP2530167A1 (en) 2006-05-11 2012-12-05 Raindance Technologies, Inc. Microfluidic Devices
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2077912B1 (en) 2006-08-07 2019-03-27 The President and Fellows of Harvard College Fluorocarbon emulsion stabilizing surfactants
WO2008097559A2 (en) 2007-02-06 2008-08-14 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US8592221B2 (en) 2007-04-19 2013-11-26 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
EP4047367A1 (en) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Method for detecting target analytes with droplet libraries
WO2010111231A1 (en) 2009-03-23 2010-09-30 Raindance Technologies, Inc. Manipulation of microfluidic droplets
US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
US10837883B2 (en) 2009-12-23 2020-11-17 Bio-Rad Laboratories, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
EP4484577A3 (en) 2010-02-12 2025-03-26 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9562897B2 (en) 2010-09-30 2017-02-07 Raindance Technologies, Inc. Sandwich assays in droplets
EP3412778A1 (en) 2011-02-11 2018-12-12 Raindance Technologies, Inc. Methods for forming mixed droplets
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
EP3216872B1 (en) 2011-06-02 2020-04-01 Bio-Rad Laboratories, Inc. Enzyme quantification
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
WO2013120089A1 (en) 2012-02-10 2013-08-15 Raindance Technologies, Inc. Molecular diagnostic screening assay
EP2844768B1 (en) 2012-04-30 2019-03-13 Raindance Technologies, Inc. Digital analyte analysis
WO2014172288A2 (en) 2013-04-19 2014-10-23 Raindance Technologies, Inc. Digital analyte analysis
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
US10998178B2 (en) 2017-08-28 2021-05-04 Purdue Research Foundation Systems and methods for sample analysis using swabs
CN110045035B (zh) * 2019-04-30 2021-05-11 上海交通大学 唾液中的胃癌voc标志物及其在制备胃癌诊断试剂中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050181464A1 (en) * 2002-04-04 2005-08-18 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from bacteria
US6998241B2 (en) * 2002-09-11 2006-02-14 Kimberly-Clark Worldwide, Inc. Antibody pair screening methods

Also Published As

Publication number Publication date
US20080138806A1 (en) 2008-06-12
TWI317811B (OSRAM) 2009-12-01
US20090170100A1 (en) 2009-07-02

Similar Documents

Publication Publication Date Title
TW200825414A (en) Biomarker molecule of gastrointestinal disease and measurement method thereof
Peek Jr et al. Detection of Helicobacter pylori gene expression in human gastric mucosa
Shimoyama et al. CagA seropositivity associated with development of gastric cancer in a Japanese population.
Lin et al. Comparative immunoproteomics of identification and characterization of virulence factors from Helicobacter pylori related to gastric cancer
Pérez‐Pérez et al. Country‐specific constancy by age in cagA+ proportion of Helicobacter pylori infections
Weiss et al. Comparison of PCR and other diagnostic techniques for detection of Helicobacter pylori infection in dyspeptic patients
Gholi et al. Helicobacter pylori FliD protein is a highly sensitive and specific marker for serologic diagnosis of H. pylori infection
Delchier et al. Helicobacter Pyloriand Gastric Lymphoma: High Seroprevalence of Caga in Diffuse Large B-Cell Lymphoma But Not in Low-Grade Lymphoma of Mucosa-Associated Lymphoid Tissue Type
EP0783579B1 (en) Antigenic fragment of the tagA gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma
Suriani et al. CagA and VacA Helicobacter pylori antibodies in gastric cancer
Afkhamipour et al. Potential gastric cancer immunotherapy: stimulating the immune system with Helicobacter pylori pIRES2-DsRed-express-ureF DNA vaccines
Sokic‐Milutinovic et al. Anti‐CagA and anti‐VacA antibodies in Helicobacter pylori‐infected patients with and without peptic ulcer disease in Serbia and Montenegro
US10022458B2 (en) Animal model protocol, diagnostic, therapeutic and vaccine against digital dermatitis
CN106947809A (zh) C6orf58基因在制备舌鳞癌诊治产品中的应用
TW201317577A (zh) 預測食道癌存活及癒後狀態之方法及其套組及微陣列晶片
KR20210149144A (ko) 두경부 표피암의 검출용 타액 바이오마커
AlFaki Detection of vacA, cagA and iceA genes of H. pylori in dyspeptic patients and their association with clinical data and histopathological abnormalities
JP5316749B2 (ja) シスプラチン耐性遺伝子診断方法及びシスプラチン治療効果遺伝子診断キット
Ohsuga et al. Comparison between in vivo and in vitro chemokine production in Helicobacter pylori infection
He et al. The effect of Helicobacter pylori infection on expression of macrophage migration inhibitory factor by T cells and macrophages in gastric mucosa
JP7486669B2 (ja) 結核、非結核抗酸菌感染疾患、及び潜在性結核診断用バイオマーカー及びその用途
JP5622156B2 (ja) シスプラチン耐性遺伝子診断方法及びシスプラチン治療効果遺伝子診断キット
US11459605B2 (en) Method for the diagnosis or prognosis, in vitro, of prostate cancer
EP2403963A1 (en) A biomarker and treatment for cancer
Khalil et al. Association of Epstein-Barr virus (EBV) with the development of nasopharyngeal carcinoma (NPC) in western region of Iraq: unmatched molecular case-control study

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees