TW200815363A - KV1.5 potassium channel inhibitors - Google Patents
KV1.5 potassium channel inhibitorsInfo
- Publication number
- TW200815363A TW200815363A TW096122064A TW96122064A TW200815363A TW 200815363 A TW200815363 A TW 200815363A TW 096122064 A TW096122064 A TW 096122064A TW 96122064 A TW96122064 A TW 96122064A TW 200815363 A TW200815363 A TW 200815363A
- Authority
- TW
- Taiwan
- Prior art keywords
- potassium channel
- channel inhibitors
- present
- relates
- imidazolidinones
- Prior art date
Links
- 108010042111 Kv1.5 Potassium Channel Proteins 0.000 title abstract 3
- 102000004425 Kv1.5 Potassium Channel Human genes 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 3
- DHIVBEZCBBHIPZ-UHFFFAOYSA-N 1-aminoimidazolidin-2-one Chemical class NN1CCNC1=O DHIVBEZCBBHIPZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000001746 atrial effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81509106P | 2006-06-20 | 2006-06-20 | |
| US11/765,359 US7504517B2 (en) | 2006-06-20 | 2007-06-19 | Kv1.5 potassium channel inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200815363A true TW200815363A (en) | 2008-04-01 |
Family
ID=38582320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW096122064A TW200815363A (en) | 2006-06-20 | 2007-06-20 | KV1.5 potassium channel inhibitors |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7504517B2 (https=) |
| EP (1) | EP2035392A1 (https=) |
| JP (1) | JP2009541343A (https=) |
| KR (1) | KR20090021223A (https=) |
| CN (1) | CN101573341A (https=) |
| AR (1) | AR061523A1 (https=) |
| AU (1) | AU2007260985A1 (https=) |
| BR (1) | BRPI0713320A2 (https=) |
| CA (1) | CA2655574A1 (https=) |
| CL (1) | CL2007001794A1 (https=) |
| CO (1) | CO6150173A2 (https=) |
| CR (1) | CR10527A (https=) |
| EC (1) | ECSP088994A (https=) |
| MX (1) | MX2008016399A (https=) |
| NO (1) | NO20085252L (https=) |
| PE (1) | PE20080942A1 (https=) |
| RU (1) | RU2008150465A (https=) |
| TW (1) | TW200815363A (https=) |
| WO (1) | WO2007149874A1 (https=) |
| ZA (1) | ZA200810763B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2008150465A (ru) * | 2006-06-20 | 2010-07-27 | Вайет (Us) | Ингибиторы калиевых каналов подтипа kv1.5 |
| RU2373934C1 (ru) * | 2008-03-19 | 2009-11-27 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Применение производных глутаровой кислоты или их фармацевтически приемлемых солей в качестве противоаритмических средств |
| CN101544580B (zh) * | 2009-04-28 | 2019-03-15 | 大连凯飞精细化工有限公司 | R-alpha-氨基-4-甲氧基苯乙酰胺的合成方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4099009A (en) * | 1977-04-11 | 1978-07-04 | Morton-Norwick Products, Inc. | 1-(4-chlorophenyl)-3-(1-ureido)-2-imidazolidinone |
| SK94393A3 (en) | 1992-09-11 | 1994-08-10 | Thomae Gmbh Dr K | Cyclic derivatives of urea, process for their production and their pharmaceutical agents with the content of those |
| DE4332168A1 (de) | 1993-02-22 | 1995-03-23 | Thomae Gmbh Dr K | Cyclische Derivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| HUP9901024A2 (hu) | 1996-01-26 | 1999-09-28 | Vertex Pharmaceuticals Incorporated | Telített azolok oxoszármazékai, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk |
| EP0891353A4 (en) | 1996-04-03 | 2001-08-08 | Merck & Co Inc | FARNESYL PROTEIN TRANSFERASE INHIBITORS |
| US7129359B2 (en) | 2002-07-09 | 2006-10-31 | National Health Research Institutes | Imidazolidinone compounds |
| US7544812B2 (en) | 2001-11-30 | 2009-06-09 | Eli Lilly And Company | Peroxisome proliferator activated receptor agonists |
| US7189856B2 (en) | 2001-12-28 | 2007-03-13 | Gideon Shapiro | Non-peptide somatostatin receptor ligands |
| AU2003302027A1 (en) | 2002-11-21 | 2004-06-15 | Vicore Pharma Ab | New tricyclic angiotensin ii agonists |
| JP2004262903A (ja) | 2003-03-04 | 2004-09-24 | Japan Science & Technology Agency | アジリジン類の製造方法 |
| US7259174B2 (en) | 2004-05-25 | 2007-08-21 | National Health Research Institutes | Imidazolidinone compounds |
| TW200624429A (en) | 2004-09-07 | 2006-07-16 | Glaxo Group Ltd | Novel cysteine protease inhibitors |
| KR100677149B1 (ko) | 2004-11-12 | 2007-02-02 | 삼성전자주식회사 | 잉크 조성물 |
| RU2008150465A (ru) * | 2006-06-20 | 2010-07-27 | Вайет (Us) | Ингибиторы калиевых каналов подтипа kv1.5 |
-
2007
- 2007-06-19 RU RU2008150465/04A patent/RU2008150465A/ru not_active Application Discontinuation
- 2007-06-19 KR KR1020097000926A patent/KR20090021223A/ko not_active Withdrawn
- 2007-06-19 CN CNA2007800285697A patent/CN101573341A/zh active Pending
- 2007-06-19 JP JP2009516686A patent/JP2009541343A/ja not_active Withdrawn
- 2007-06-19 AU AU2007260985A patent/AU2007260985A1/en not_active Abandoned
- 2007-06-19 BR BRPI0713320-0A patent/BRPI0713320A2/pt not_active IP Right Cessation
- 2007-06-19 EP EP07798773A patent/EP2035392A1/en not_active Withdrawn
- 2007-06-19 CA CA002655574A patent/CA2655574A1/en not_active Abandoned
- 2007-06-19 US US11/765,359 patent/US7504517B2/en not_active Expired - Fee Related
- 2007-06-19 MX MX2008016399A patent/MX2008016399A/es unknown
- 2007-06-19 CL CL2007001794A patent/CL2007001794A1/es unknown
- 2007-06-19 WO PCT/US2007/071587 patent/WO2007149874A1/en not_active Ceased
- 2007-06-19 AR ARP070102688A patent/AR061523A1/es unknown
- 2007-06-19 PE PE2007000779A patent/PE20080942A1/es not_active Application Discontinuation
- 2007-06-20 TW TW096122064A patent/TW200815363A/zh unknown
-
2008
- 2008-11-06 US US12/266,212 patent/US7803827B2/en not_active Expired - Fee Related
- 2008-12-16 NO NO20085252A patent/NO20085252L/no not_active Application Discontinuation
- 2008-12-18 CR CR10527A patent/CR10527A/es not_active Application Discontinuation
- 2008-12-19 EC EC2008008994A patent/ECSP088994A/es unknown
- 2008-12-19 ZA ZA200810763A patent/ZA200810763B/xx unknown
- 2008-12-19 CO CO08135447A patent/CO6150173A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20085252L (no) | 2009-01-13 |
| BRPI0713320A2 (pt) | 2012-02-07 |
| US7504517B2 (en) | 2009-03-17 |
| WO2007149874A8 (en) | 2008-03-20 |
| CR10527A (es) | 2009-02-19 |
| AU2007260985A1 (en) | 2007-12-27 |
| CO6150173A2 (es) | 2010-04-20 |
| KR20090021223A (ko) | 2009-02-27 |
| JP2009541343A (ja) | 2009-11-26 |
| CA2655574A1 (en) | 2007-12-27 |
| EP2035392A1 (en) | 2009-03-18 |
| MX2008016399A (es) | 2009-02-03 |
| WO2007149874A1 (en) | 2007-12-27 |
| CL2007001794A1 (es) | 2008-01-18 |
| US20090069342A1 (en) | 2009-03-12 |
| US20070299120A1 (en) | 2007-12-27 |
| AR061523A1 (es) | 2008-09-03 |
| CN101573341A (zh) | 2009-11-04 |
| ECSP088994A (es) | 2009-01-30 |
| PE20080942A1 (es) | 2008-09-03 |
| ZA200810763B (en) | 2009-09-30 |
| US7803827B2 (en) | 2010-09-28 |
| RU2008150465A (ru) | 2010-07-27 |
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