TW200810790A - Dry type nano manufacturing process for natural organic substance without the need of adding dispersing agent and excipient and product manufactured therefrom - Google Patents

Abstract

This invention relates to a dry type nano manufacturing process for a natural organic substance without the need of adding a dispersing agent and an excipient and product manufactured therefrom, capable of being used to process multiple materials into nano-class particles, comprising steps of: ultra-micro pulverization and fluidised bed spray granulation and drying. Multiple nano-sized primary particles are formed after ultra-micro pulverization process and the fluidised bed spray granulation can stably wrap and concentrate the primary particles into secondary particles with larger diameters. Accordingly, raw materials can totally be manufactured to nano-sized particles directly. Further, the nano size characteristics of the particles can be utilized to achieve better dispersion and excipient effects and increase extraction rate, and the dry process can be used to prevent water solvable nutrient loss, so as to enable this invention to be easily granulated and capleted without the need of adding dispersing agent and excipient, and make the products have better mouthfeel and be easily absorbed.

Description

200810790 IX. Description of the invention: [Technical field to which the invention pertains] The present invention relates to a food and Chinese herbal medicine nano-chemical process and a product thereof, which means that no dispersant or excipient is added. The natural organic dry type neat pure process and the products made therefrom. [Prior Art] Turtle

▲The method of extracting the ingredients in food is to extract the active ingredients in the food by high-temperature heating or solvent extraction. After the extraction, the food is discarded. The nutrients of the whole food cannot be collected completely. However, high-temperature cookers tend to damage the nutrients contained in the ingredients, and solvent extraction has the problem of chemical residues. Another method for processing processed foods is to dry the foodstuffs in a high-temperature drying state so as to be crispy and anhydrous, which retains the overall coffin (for example, if it is a plant material, it retains its cellulose). However, during the treatment, high temperature heating will still destroy some nutrients, and if the ingredients contain oil and fat, and 'after high temperature treatment, it will easily become sticky, which will increase the inconvenience of treatment'. Therefore, this method still cannot be completed. Preserved and used in the ingredients. Nutritional ingredients. There is a way to process the ingredients in order to dry the whole ingredients, and then perform preliminary crushing by chopping, breaking, etc., and then grind into small particles by grinding, but the size of the product obtained by grinding is generally When the ingredients used in the rice are 2 to 4, the grain size of this grade is still relatively thick and the sputum is poor, and most of the nutrients are still stored in the intact cells of the food. Less easy to absorb by the human body. In addition, in the grinding process 5 200810790: 彺彺 will easily cause the food to coke, carbonization and other deterioration due to the heat of friction, and will destroy the nutrients contained in it, and at the same time, if it contains more oil and sugar, it is easy. The case of causing viscous during grinding due to high temperature is also unfavorable for processing, and it is also incapable of obtaining complete nutrients in the food. In terms of preparing nano particles, the following methods are known in the industry: (1) Vacuum condensation method: after vacuum evaporation, heating and high-frequency induction treatment, the material is cooled and the raw material is broken into Naizi. The purity and crystallinity of the nanoparticles prepared by this method are good, and the particle size can be controlled, but the technical equipment requirements are also high, which may increase the production cost 'and the heating process if used for processing the ingredients' It will destroy most of the nutrients in the ingredients. (2) Mechanical ball milling method · Suitable for pure elements, alloys or composite materials. Although this method has the advantages of simple operation and low cost, the purity of the products produced and the particles are not in need of improvement. Xin (3) Vapor deposition method · has high purity and narrow particle size distribution, but it is more suitable for chemical reaction synthesis of metal compounds, and is not suitable for processing of food materials. (4) Precipitation method: adding a suitable precipitant to the salt solution to cause precipitation and then heat treatment to prepare nano particles, although simpler, the obtained product has lower purity and relatively larger particle size. Moreover, since the salt solution is used as a raw material, it is only suitable for preparing an oxide. (5) Hydrothermal synthesis method: a method in which the reactants are firstly subjected to high temperature and high pressure, and then separated by water, followed by heat treatment to obtain nano particles, although the purity and dispersibility of the heterons prepared in 200810790 are high. Good recording is easy to control, but because of the southerly pressure and southward pressure in the process, if you want Tianzhan, if it is used to treat the ingredients, it may damage the nutrients in the ingredients, so that the gentleman and the Ba Shi Yu Chengdao are limited. It is not suitable for use in the food industry. (8) Sol-gel method: the metal compound (mainly the element of the metal oxide 4 chemical element periodic table, the element of the group ~ group 1) is dissolved in the solution only in order After treatment of bismuth/cheng, gluten and gel, and then low-temperature heat treatment to obtain nano particles, this method has many kinds of reactive species, difficult to compare, and easy to control, but the material types that can be used are also subject to (4) , does not apply to food raw materials. > () micro-living liquid method. Using the interaction between different solvents and surfactants, the substance to be treated is surrounded to form microbubbles, nucleation, aggregation in microbubbles Knot, agglomeration, heat treatment to produce nano particles It has the characteristics of monodisperse and good interfaciality, but is more suitable for processing semiconductor materials of the πth to the VIth of the periodic table of the chemical elements. (8) Fluid collision method: suitable for fragile raw materials, high speed for raw materials Sorghum 'make it collide and disperse and separate to form nano-sized particles, but this method is suitable for fragile products, and the product particles produced are not uniform, and the production is not large, so it is relatively The practical value of the product is also low. In addition to the current introduction of the conventional nanoparticle preparation method, in response to the current trend of nano-chemicals, the food and hygiene industry is also actively developing products for nano-chemical products. 'For example, there are currently developed methods for making nano-particles by using grinding technology, most of which are mining (four) grinding type. There are still some problems to be solved in this method. For example, (1) temperature problem: grinding process (four) into high temperature, It is easy to destroy or deteriorate the food ingredients. For example, the water damage of 200810790, the surface tension of the colloid will affect the functional group coating of each component, and must be controlled by an appropriate cooling system. The temperature of the process, (2) the problem of stagnation: some foods, especially plants or Chinese herbal medicines, contain more sugars and oils, even gums, which tend to stick during the grinding process and cannot achieve better crushing. Effect, (3) Contamination problem: The material of the abrasive used in grinding may affect the purity of the food, and may even affect the nature of the active ingredient. In addition, during the grinding process, in order to avoid re-aggregation of the nano-particles, it is sticky. Cementation

In addition, a dispersing agent or a surfactant may be added during the grinding process, and this method will also clarify the purity and efficacy of the end product. Before the finished food is made into a finished product, in order to facilitate the packaging and control the release time of the active ingredient, the dosage form will be prepared. In order to facilitate the molding of the tablet, an additional excipient will be added before the tableting, and the finished product will be diluted. The disadvantage of purity and increased raw material cost. Although both the academic and industrial circles have developed different curing treatment technologies for food nanocrystallization, there is still much room for improvement. The high solubility, high dissolution, and high absorption that can be achieved by Naihua Chemical High bio-use and can preserve the daily characteristics and completeness of food ingredients, and the advantages of the health food: the natural organic matter such as Chinese herbal medicine has formed a trend, and in order to better production conditions and product quality, There is a continuing need to develop natural organic production technology to 'promote the progress of the industry and provide more embarrassing products for human beings. SUMMARY OF THE INVENTION Therefore, the purpose of high extraction rate and the purpose of the present month is to provide a raw material availability and easy to obtain active ingredients, high product activity, easy absorption, and easy to form a different type of π type. A natural organic dry process for adding a dispersant, an excipient, and a product made therefrom. ... 疋 疋 'The present invention does not require the addition of dispersants, excipients of the natural organic dry non-ricization process, can be used to treat a wide variety of raw materials to form nano-sized particles' in sequence including the following steps: (4) pre-treatment (four): will be fresh The raw material is processed into a dry material that is easy to be ultra-finely pulverized; • β(1) ultrafine: broken: the pressure pulse force of the gas flow ring caused by a gas flow ring π formed by a flow of a surrounding flow and a pulse of σ ν frequency And the micro-powder gas separation equipment (using the principle of air buoyancy and gap selection to separate particles of different specific gravity) directly acts on the raw materials to cause it to collapse and separate, forming a plurality of primary particles in nanometer size; (Η) spray granulation and Drying: spraying a mist for encapsulation of the primary particle agglomerates and forming secondary particles having a larger particle diameter than the primary particles, and repeating granulation in a floating bed to expand the particle size of the secondary particles, and Use dry φ dry air to achieve dehumidification and drying effect; · (b) Post-treatment procedure: The granulated secondary particles are made into different dosage forms according to the characteristics of use and protected by appropriate packaging. 'Step ⑷ ⑻ steps to follow material properties acquired and demand decide whether to execute or cancel. 〇〇 Through these steps, the raw materials (eg, %, whole parts of the whole plant) can be made into a product containing nanometer-sized particles without damaging or consuming the active ingredients. Further, different types of finished products are prepared, and the prepared product has the advantages of high active ingredient activity and easy extraction of 200810790 for absorption and absorption by the human body. The product of the invention without adding dispersing agent and excipient is prepared by the foregoing steps. After the production, the particle size is in the nanometer grade, and the gas stream is directly used in the process to achieve the dispersion effect without using a dispersing agent, and The characteristics of the raw materials and the use requirements 'coordinate with appropriate release, absorption' and dosage form technology, appropriate coating, embedding, for example, directly into the micro-powder, repeated granulation to expand, increase the particle size into (four), Lang money Read the day-to-day position and position of each of the filaments, so that the product can perform better. Through the above process, the invention can use any part of the food material, and physically break the food cell through the physical method, so that the ingredients in the cell of the food material can be released into the form of the nanometer particles, and directly by the gas. Good dispersion effect without adding dispersant, and has the best processability, applicability and mouthfeel, no need for excipients and disintegrants, easy to mix, easy to retain active ingredients, extraction rate High and easy to absorb and utilize the effects and characteristics of the human body. [Embodiment] The present invention does not require the addition of a dispersant, an excipient, a natural organic dry-type nanocrystallization process, and the foregoing and other technical features and effects of the products made therefrom, in the following detailed description of the preferred embodiments. It will be clearly understood. Before the present invention is described in detail, it is to be noted that in the following description, similar process steps are denoted by the same reference numerals. Recently, due to the importance and potential of nanotechnology, it has attracted the attention of scholars, industry, and the general public. It can be said that nanotechnology is the most important technology trend of the 21st century and 200810790 and the hope of the new economy. The main components of food, n&fn vitamins, cellulose, trace elements and other organic substances, and the necessary inorganic and active ingredients, the chemical structure of which is of the Amy (A) size and can be settled in the nanometer size. It can be used for absorption and utilization of cells in micron-sized organisms. However, if the cells are not broken, these nutrients or active ingredients will not be easily released and cannot be fully absorbed. When the substance reaches the nanometer size, it is due to its specific surface area. Increased, it can improve its biochemical reactivity and increase the absorption efficiency of the human body. Combined with other biochemical reactions, #放放 and absorption technology, it can control the efficacy of active ingredients and nutrients in food. 1 is a first preferred embodiment of a natural organic nano-drying process without dispersing agents and excipients, which is suitable for producing ultrafine powders of high-fiber foods, and includes the following steps in order. Step 101 is to select materials for cleaning. · According to the products to be produced, select the appropriate ingredients, such as plants containing more fiber, or ingredients containing specific effective knives, and then wash and sterilize these ingredients and plants. spare. v Step 102 is saccharification separation. The high fiber-containing food material is put into a liquid, and the appropriate decomposition enzyme is sub-incorporated to cause the food material to produce a liquefaction knife in the liquid, and the starch in the plant food material, The sugar is broken down and separated, leaving only fiber and protein. ^Step 103 is dry storage: drying the ingredients to reduce the water damage value of the ingredients to less than 15% to avoid destroying the ingredients in the ingredients and to facilitate storage and non-corrosion. Step 104 is to mix and mix according to the required characteristics and efficacy of the finished product. » 11 200810790 The ingredients that have been dried and processed are pre-mixed as a subsequent pulverizing process. _Materials can also be used as the raw material for subsequent processes. Step 105 is microparticle pulverization. The mechanical material of the material of step 104 is subjected to preliminary fine pulverization treatment by using a mechanical physical formula such as chopping or breaking, so that the food materials are broken into smaller pieces to facilitate rapid subsequent processing. vStep 106 is ultrafine pulverization: in order to utilize the commercially available ultrafine grinding machine-related equipment, the high-frequency gas flow pressure pulse caused by it is applied to the fragments generated in the step 1〇5 to break the cells of the foodstuff, and Pulling out the van der waals f(10)^ between the individual sputum particles in the cytoplasm, so that the components are redispersed to form a majority of primary particles with particle sizes ranging from 5 nm to loo nm (eg attachments) As shown in the figure, in the case where the primary particles are photographed under a transmission electron microscope (Transmission Electron Microscope, TEM 'Model: JEOL JEM-2010, manufactured by Japan), the particles of the primary particles are displayed. The diameter is as small as 5 nm). Step 107 is spray granulation and drying: in order to utilize a floating bed spray granulation φ dryer, the spray mist is supplied to the primary particles combined with the embedding sub-stage produced by the step 106, and the particle size is larger than the primary particles and has a better flow. The secondary particles are mainly composed of secondary particles of each nanometer-sized primary functional group with electrostatic charge and embedded into a plurality of secondary particles which are loosely coupled and positively and negatively ionically coordinated (as shown in Annex II). The secondary particles are under a transmission electron microscope, and the image of the shape of the secondary particles of the primary particles is up to about 200 nm, thereby protecting the primary particles. The active ingredient reduces the influence of the humidity and the heat in the external environment to produce agglomeration of the powder, and utilizes the preliminary formation of the secondary particles and the continuous input of the primary particles in the floating bed 200810790 to re-granulate in the moving bed to amplify The particle size of the # secondary particle, and the effect of using the dry (four) flow to achieve (four) dryness, the towel, the #: secondary particle particle range is between 250 nm and 2 mm for convenient use.

- Step 108 is a screening: the granulation of the secondary particles according to the direct weight and particle size 'Using a gas separation classifier and sieve mesh of different mesh sizes, divided into fine powder, powder and granules Wherein, the particle size of the micropowder ranges from 5 nm to 800 nm, and the particle size ranges from _ nm to 800 μm, and the particle size range of the granules is 6 〇〇. It can be properly packaged according to different dosage forms. Step 109: injecting and removing powder, collecting and drying the granules into a spinning type, so as to conveniently eat and control the release and absorption time of the microparticles (4), and inject the ingot into the ingot by the effect of long-acting slow release. After the agent, some dust adheres to the surface of the tablet, and the roller brush can be used to mix the airflow, and the dust is removed and recycled or granulated. Step 110 is a filling package: forming a micro-powder, a powder, a granular d and a k h 彳 according to the fine particle form, and filling the package with a suitable container. Among them, steps 101 to 105 are so-called pre-treatment procedures, mainly for processing fresh food materials into a relatively dry fragment pattern, in order to perform ultrafine pulverization of the step 106 to form nano-sized particles. It is also possible to directly select the dried food, for example, tea leaves, and directly perform the ultrafine pulverization step. In addition, the steps to step 11 are used as a post-treatment procedure, and the primary particles after granulation can be screened and classified according to the particle size. Different dosage forms to provide different application needs. The transmission electron microscope photo shown in Annexes 1 and 2 shows that the natural organic material h can be physically mashed into one nano-scale one-time drag. Do not recognize human particles, and can use these - under = Valli force to form a more stable, and the particle size is greater than the above-mentioned level:: scorpion, and the primary and secondary particles are still ", And #'n1 The present invention does have a function that can be performed. 轲Processing into a nano-sized particle Referring to Fig. 2 'is the present invention, the need for the glutinous rice, the addition of the granules, the dryness of the excipients The second preferred embodiment of the method is applicable to ultrafine powders containing 牿定古4\ a, producing non-oriented fibers, but effective as food, such as green tea, activated carbon, a car = dried, fruits, vegetables, The processing steps of grains and the like are substantially the same as those of the first embodiment, except that the dry screening of the saccharification separation fish (10) of (4) m can be omitted due to the second preferred embodiment = high fiber material to be treated (see figure) Hey, the rest of the steps are handled. The embodiment is the same, so it will not be described here. After the ultrafine pulverization and spray granulation and drying of the food material in the second preferred embodiment, most of the direct compression molding of the key type packaging is long-lasting. Effect of the release. In the first and second preferred embodiments, the main purpose of making the food material into a suspected form is to control the speed of the release of the secondary particles in the body to make the original food effective. It is easier for the ingredients to reach a better position, but it should not be used to limit the type of ϋ 镗 削 , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , In the form of ingots, capsules, etc., it is also possible to re-dissolve the microparticles in a suitable liquid and package them in a drink type, which has the characteristics that the active ingredients in the coffin can be easily eaten and absorbed and utilized by biological cells. 14 200810790 Worth Illustrated 熹, 太兮隹^ + + — - In the preferred embodiment of the second embodiment, when performing ultra-fine pulverization, the effect of nano-materialization is achieved by using high-frequency gas +, and the principle of action is = :force

Intermittently release the air force generated by the repeated force to force the collision. ',;'', to generate a high-frequency airflow ring field as the carrier formed in step 1〇5' to make particles between particles or particles and equipment The impact and friction between the inner wall f, together with the breakage of the particles when the particles are accelerated, achieve the purpose of breaking the food cells and releasing the nano-sized particles. In addition, due to the high frequency of retraction and release, the air is replaced in a large amount, so that this kind of pulverization method is less likely to retain heat. Therefore, even if the pulverization process, the particles will only be in each other. ##擦'温升不高 too high' A property is particularly important for the ultrafine pulverization of heat sensitive materials, and is also more resistant to the composition of the raw materials. In addition to the use of high-frequency airflow pulse pressure to achieve the crushing and disintegration of food cells and the release of nano-sized particles, the ruthenium can also be used to screen the particle size by airflow to achieve easy dispersion of the primary particles. The effect of the average sentence, without the need to use additional dispersant'. In addition, because the secondary particles are in the form of rice and size, the van der Waals force between the particles is more obvious, and the surface energy of each particle is also very High, and can use the van der Waals force between particles to accelerate. Its dust collection and granulation, and because the whole process is carried out in a dry environment, the formed particles are not wetted, so they can maintain high surface energy. As long as it is slightly squeezed, it can be agglomerated into agglomerates, and the direct granulation tablet does not need to use excipients and disintegrants, so that the content of active ingredients in the finished product is relatively high. 15 200810790 ❿ The application of ultrafine pulverization technology in the food processing industry has two main aspects: on the one hand, it can improve the sensation of food and facilitate the absorption of nutrients, such as 'micronizing the fiber in the plant to improve the fiber food. The taste is not compromised by the fiber's work 35' and is easier for consumers to accept. On the other hand, raw materials that cannot be fully absorbed and utilized can be reused, and various functional foods can be made, or new food materials can be developed and new food types can be added, thereby improving resource utilization, for example, peels and fruit cores. It is rich in silkworm value. It can be transformed into food after superfine pulverization. There are also some inedible parts of animal and plant parts such as bone, carapace and hard skin. It can also be used for ultra-fine pulverization: it is easily absorbed by the human body. The source of calcium and chitin, or the tea directly in the a; a dry state of tea powder, can make the tea contains nutrients, such as some insoluble or poorly soluble vitamins A, κ, e And most of the protein, carbohydrates and some minerals, etc., become particulate matter that is easily absorbed by the human stomach. Most of the active ingredients in the health food raw materials are difficult to extract, such as taking the food raw materials into a suitable liquid to dissolve the specific active ingredients or active ingredients in the raw materials, and then collecting the liquids and dissolved in a filtered manner. The components in the food material are extracted by purification, crystallization, etc., and the dissolved components may react with the solvent used in the process to lose activity, that is, the result of water activity destruction, or additives. It is also possible that side effects of the New Moons affect the activity and efficacy of the active ingredients. However, the raw material is pure, because it is smaller than the cells of the organism, and it is easy to enter the biological cells by eating 2, and can break through the restrictions of entering certain parts of the body, and can increase the activity and absorption of the active ingredients in the human body. Furthermore, it can be seen that the improvement and absorption of an active ingredient can be improved by using other release techniques, techniques or absorption techniques, and the efficacy of the ingredient can be controlled. Therefore, with the revolutionary changes in the food system caused by nanotechnology, nano-food materials have a relatively high absorption rate due to their small particles, which helps infants, the elderly or those with poor digestion and absorption ability to obtain the necessary nutrients. It is also applied to Chinese herbal medicines, which makes the efficacy of Chinese herbal medicines easier to play. Food nanocrystallization is the trend of the current health food market. With dry Nai/匕, the original extraction is difficult, the solubility is low, and it is not easy. The absorption and utilization of effective active ingredients absorbed by the body are greatly improved. In summary, the present invention does not require the addition of a dispersing agent, an excipient, a natural organic dry nanochemical process, and a product made therefrom, which achieves the following efficacies and advantages, so that the object of the present invention can be achieved:

1. The invention directly treats all or part of the animal and plant body after drying, and then uses special ultrafine pulverizing equipment to make nanometer-sized granules, so that various components in the raw material of the animal and plant can be utilized, except In addition to the utilization of the raw materials, the nano-chemical treatment is also used to enhance the efficacy of the present invention, and the present invention has the advantages of being of a source, and the availability and absorbability of the raw materials. =, after the raw material is processed into nanometer-sized particles, you can directly use the characteristics of Nai = Temple and the Van der Waals force between the particles without additional +. For the purpose of dispersing and ingoting, the powder and the excipient can achieve the characteristics of high purity and high performance of the finished product without adding dispersing agents and excipients. Second, the natural organic material is treated by the step 106 of the present invention. 17 200810790 The cell breakage and the large surface area of the primary particles produced can significantly improve the extraction efficiency when the specific active ingredient is subsequently extracted. 4. After the raw materials are processed into nanometer-sized granules, the taste of some high-fiber foods can be greatly improved, and it is easy to directly mix the different gluten-based products into low-fat according to the characteristics of the food raw materials. Foods with different functions such as low sugar, high protein f, and high fiber are easily absorbed by human cells, so that the present invention has the characteristics and advantages of better nutritional value.

However, the above is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, that is, the simple equivalent changes and modifications made by the scope of the present invention and the description of the invention. All remain within the scope of the invention patent. [Simplified illustration of the drawings], a flow chart of a preferred embodiment of the process of the 〜 、, 刀双刚7 process; and Fig. 2 is a first process of the dry process of the present invention without adding a dispersant or an excipient A flow chart of the preferred embodiment. Attachment #Transparent electron microscope photograph showing the majority of the secondary particles produced by the dry process of the rice process: the primary particles are gathering and agglomerating. 7 Attachment... A transmission electron microscope photo showing the secondary particles of formula 71 prepared by the naturalization process of natural organic matter.结形# 18 200810790 [Main component symbol description] None

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Claims (1)

200810790, Patent Application: 1. A dry organic nano-particle of natural organic matter without the need to add a dispersing, stationing, f-system (four) agent, comprising the following steps: organic material to form a nano-scale material, force pulse directly acts on Raw materials to form a plurality of primary particles in nanometer size; and (8) spray granulation and drying: spray mist is embedded in ▲ and formed to have a larger particle size than the first time _: human = • repeated granulation in a floating bed Amplification "...: one person particle' and in 'S, Stong Temple recognizes the particle's sister private, fen 4丨ί 13⁄4 dry airflow achieves the effect of dehumidification and drying. 2. According to the patent application scope j |擤% & 幻幻..., adding a dispersing agent, shaping the natural organic matter of the dry type of nano-chemical directing 忐66 a 八, the ultra-fine pulverization step 3: the particle size range of the human particles is In the range of 5nm~1〇〇nm. 3 · According to Shen Qing patent Fan Didi 2, the natural organic matter without adding dispersing agent is too dry and half-shaped. It is pressed into a tablet or block type packaging. Direct 4 ·Based on the scope of patent application筮The agent does not need to add a dispersing agent, a shaped natural organic dry nano drying step described in the organic enthalpy, and the spray granulation and mm. The particle size range of the uncle is 250 mn~2 5. According to the 4th dose of the patent application scope, the natural organic matter dry, phase ',, & add dispersant, form a tablet or block type = process 'the secondary particles are pressed. 6. According to the scope of patent application ^ ^ 斤之的..., for the addition of dispersant, 20 200810790 agent, organic matter dry nano-chemical process, step-by-step _ in the step of cattle (1) (a) Dan in y-easy - micro-^ dry order (4) Fresh material processing is 7 · According to the Shenqing Patent Fan Di 6 item, the natural organic dry-type nano-chemical process without adding dispersant and ΜP agent, further includes: after (:) (8) post-treatment (4) In the use of the characteristics of the h-door order to k-pull the secondary particles according to I into different dosage forms and appropriate packaging protection. w 1 according to the scope of application of the scope of the seventh paragraph without the need to add dispersion Agent: natural organic dry type nano-chemical In the process, the secondary particles are compressed into a tablet or a block type package. The process described in the first paragraph of the patent application does not require blood: dilute, excipient natural organic products, ^ ι〇·: According to the ninth item of the patented dry circumference, the natural organic product without adding a dispersing agent, wherein the particle size range of the product is between 5 nm and 2 mm 〇 11. According to the declaration The natural organic product described in claim 9 which does not require the addition of a dispersing agent or an excipient, wherein a raw material of the product is subjected to ultrafine pulverization treatment, and a plurality of particle sizes ranging from 5 nm to between are formed. Primary particles. According to the towel, please use the natural organic product without dispersing agent and excipients. The primary particles will be sprayed and granulated and dried to form a majority of the particle size range of 25〇. Secondary particles between nm and 2 mm. 21 200810790 According to the scope of the patent application, there is no need to add dispersant or shape, ', organic product', 'the product is directly packaged in micro-powder type' and its particle size range is preferably 5mn~ 800 nm.天然. The natural organic product without adding a dispersing agent or excipient according to the thirteenth item of the Chinese Patent (4), wherein the product is made into a micro-powder type to be dissolved in a liquid, and can be further advanced through the transition. Efficient extraction yields specific active ingredients within the product. 15. The natural organic product without the addition of a dispersant or an excipient according to the scope of claim 1 of the patent application, wherein the product is packaged in a powder form, and the particle size range is preferably 6 〇〇 nm. ~800 μιη. 16. A natural organic product which does not require the addition of a dispersant or an excipient as described in the scope of claim 1G, wherein the product is packaged in a granule form and preferably has a particle size range of 600 μm to 2 mm. 17. According to the scope of the patent application, the natural organic product without adding a dispersing agent or an excipient as described in Item No. 9 to Item 13, wherein the product is _ directly pressed into the ingot Packed in package or block form. 18. The natural organic product according to claim 15, wherein the secondary particles are directly compressed into a tablet or a block type package. twenty two