TW200637872A - Thiol group protection and cyclization in solid-phase peptide synthesis - Google Patents
Thiol group protection and cyclization in solid-phase peptide synthesisInfo
- Publication number
- TW200637872A TW200637872A TW094137400A TW94137400A TW200637872A TW 200637872 A TW200637872 A TW 200637872A TW 094137400 A TW094137400 A TW 094137400A TW 94137400 A TW94137400 A TW 94137400A TW 200637872 A TW200637872 A TW 200637872A
- Authority
- TW
- Taiwan
- Prior art keywords
- cyclization
- solid
- thiol group
- peptide synthesis
- phase peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
- C07K1/086—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04025395 | 2004-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200637872A true TW200637872A (en) | 2006-11-01 |
Family
ID=36090794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094137400A TW200637872A (en) | 2004-10-26 | 2005-10-26 | Thiol group protection and cyclization in solid-phase peptide synthesis |
Country Status (11)
Country | Link |
---|---|
US (1) | US20080108790A1 (zh) |
EP (1) | EP1807442A1 (zh) |
JP (1) | JP2008529969A (zh) |
KR (1) | KR20070083815A (zh) |
CN (1) | CN101072791B (zh) |
AU (1) | AU2005298840B2 (zh) |
BR (1) | BRPI0518390A2 (zh) |
CA (1) | CA2584906A1 (zh) |
IL (1) | IL182751A0 (zh) |
TW (1) | TW200637872A (zh) |
WO (1) | WO2006045603A1 (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008080845A1 (en) * | 2006-12-29 | 2008-07-10 | F. Hoffmann-La Roche Ag | Methods for the synthesis of cyclic peptides |
KR20100036326A (ko) * | 2007-06-29 | 2010-04-07 | 론자 아게 | 프람린타이드의 생산 방법 |
TWI395752B (zh) * | 2008-09-03 | 2013-05-11 | Scinopharm Taiwan Ltd | 製造比伐蘆汀(bivalirudin)之方法 |
CN102180943A (zh) * | 2010-12-16 | 2011-09-14 | 深圳市健元医药科技有限公司 | 一种辅助降血糖多肽药物的生产工艺 |
FR2981352B1 (fr) * | 2011-10-17 | 2015-07-03 | Centre Nat Rech Scient | Procede de synthese de proteines |
CN102875639A (zh) * | 2012-09-26 | 2013-01-16 | 深圳翰宇药业股份有限公司 | 一种肽的固相合成方法及其合成的肽 |
CN112111001B (zh) * | 2019-06-19 | 2021-10-29 | 翰宇药业(武汉)有限公司 | 胸腺肽Tα-1的合成方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE205854T1 (de) * | 1991-11-19 | 2001-10-15 | Amylin Pharmaceuticals Inc | Peptide als amylin-agonisten und ihre verwendung |
US5889146A (en) * | 1997-11-26 | 1999-03-30 | Institute Of Nuclear Energy Research | Method for synthesis of bifunctional chelating agents-peptides |
US6087334A (en) * | 1998-08-21 | 2000-07-11 | Amylin Pharmaceuticals, Inc. | Anti-diabetic peptides |
US6476186B1 (en) * | 2000-05-23 | 2002-11-05 | Institute Of Nuclear Energy Research | Process for preparing octreotide and derivatives thereof |
DK1337549T3 (da) * | 2000-11-27 | 2006-07-31 | Lonza Ag | Fremgangsmåde til foldning af kemisk syntetiserede polypeptider |
-
2005
- 2005-10-26 EP EP05810158A patent/EP1807442A1/en not_active Withdrawn
- 2005-10-26 BR BRPI0518390-1A patent/BRPI0518390A2/pt not_active IP Right Cessation
- 2005-10-26 US US11/666,171 patent/US20080108790A1/en not_active Abandoned
- 2005-10-26 WO PCT/EP2005/011476 patent/WO2006045603A1/en active Application Filing
- 2005-10-26 JP JP2007538330A patent/JP2008529969A/ja active Pending
- 2005-10-26 KR KR1020077009496A patent/KR20070083815A/ko not_active Application Discontinuation
- 2005-10-26 AU AU2005298840A patent/AU2005298840B2/en not_active Ceased
- 2005-10-26 CN CN2005800365194A patent/CN101072791B/zh not_active Expired - Fee Related
- 2005-10-26 TW TW094137400A patent/TW200637872A/zh unknown
- 2005-10-26 CA CA002584906A patent/CA2584906A1/en not_active Abandoned
-
2007
- 2007-04-23 IL IL182751A patent/IL182751A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2008529969A (ja) | 2008-08-07 |
CN101072791B (zh) | 2011-01-19 |
AU2005298840A1 (en) | 2006-05-04 |
US20080108790A1 (en) | 2008-05-08 |
IL182751A0 (en) | 2007-07-24 |
BRPI0518390A2 (pt) | 2008-11-18 |
WO2006045603A1 (en) | 2006-05-04 |
AU2005298840B2 (en) | 2010-09-16 |
KR20070083815A (ko) | 2007-08-24 |
CA2584906A1 (en) | 2006-05-04 |
CN101072791A (zh) | 2007-11-14 |
EP1807442A1 (en) | 2007-07-18 |
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