TW200607493A - Potassium channel inhibitors - Google Patents

Potassium channel inhibitors

Info

Publication number
TW200607493A
TW200607493A TW094125011A TW94125011A TW200607493A TW 200607493 A TW200607493 A TW 200607493A TW 094125011 A TW094125011 A TW 094125011A TW 94125011 A TW94125011 A TW 94125011A TW 200607493 A TW200607493 A TW 200607493A
Authority
TW
Taiwan
Prior art keywords
potassium channel
channel inhibitors
inhibitors
compounds
useful
Prior art date
Application number
TW094125011A
Other languages
English (en)
Inventor
Mark T Bilodeau
zhi-cai Wu
John Hartnett
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of TW200607493A publication Critical patent/TW200607493A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW094125011A 2004-07-29 2005-07-22 Potassium channel inhibitors TW200607493A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59218104P 2004-07-29 2004-07-29

Publications (1)

Publication Number Publication Date
TW200607493A true TW200607493A (en) 2006-03-01

Family

ID=35613661

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094125011A TW200607493A (en) 2004-07-29 2005-07-22 Potassium channel inhibitors

Country Status (15)

Country Link
KR (1) KR20070043985A (zh)
AR (1) AR049847A1 (zh)
BR (1) BRPI0513793A (zh)
CR (1) CR8876A (zh)
EC (1) ECSP077208A (zh)
IL (1) IL180846A0 (zh)
MA (1) MA28980B1 (zh)
MX (1) MX2007001188A (zh)
NO (1) NO20071107L (zh)
PE (1) PE20060382A1 (zh)
RU (1) RU2344134C2 (zh)
TW (1) TW200607493A (zh)
UA (1) UA88018C2 (zh)
WO (1) WO2006028590A1 (zh)
ZA (1) ZA200700477B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120029447A1 (en) * 2009-03-18 2012-02-02 Medicure International Inc. Transdermal pharmaceutical preparation and administration of tirofiban
MY169219A (en) 2012-06-11 2019-03-19 Bristol Myers Squibb Co Phosphoramidic acid prodrugs of 5 - [5 - phenyl- 4 - (pyridin- 2 - ylmethylamino) quinazolin- 2 - yl] pyridine- 3 ? sulfonamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE400551T1 (de) * 2002-01-04 2008-07-15 Neurosearch As Kaliumkanal-modulatoren

Also Published As

Publication number Publication date
MX2007001188A (es) 2007-03-21
AR049847A1 (es) 2006-09-06
NO20071107L (no) 2007-04-19
ZA200700477B (en) 2009-08-26
BRPI0513793A (pt) 2008-05-13
RU2007107408A (ru) 2008-09-10
WO2006028590A1 (en) 2006-03-16
RU2344134C2 (ru) 2009-01-20
MA28980B1 (fr) 2007-11-01
KR20070043985A (ko) 2007-04-26
UA88018C2 (ru) 2009-09-10
CR8876A (es) 2007-08-28
PE20060382A1 (es) 2006-05-15
ECSP077208A (es) 2007-02-28
IL180846A0 (en) 2007-06-03

Similar Documents

Publication Publication Date Title
WO2006015159A3 (en) Potassium channel inhibitors
IL190730A0 (en) Potassium channel inhibitors
WO2005030791A3 (en) Isoquinolinone potassium channel inhibitors
WO2005030129A3 (en) Quinoline potassium channel inhibitors
WO2007050348A3 (en) Potassium channel inhibitors
WO2005046578A3 (en) Isoquinolinone potassium channel inhibitors
WO2005030130A3 (en) Isoquinoline potassium channel inhibitors
WO2007085895A3 (en) Fap inhibitors
TWI369351B (en) 2,4-diamino-pyrimidines as aurora inhibitors
MXPA05013553A (es) Pirrolodihidroisoquinolinas como inhibidores de pde10.
TW200626068A (en) Active compounds for seed treatment
TW200621253A (en) 2-amido-thiazole-based compounds exhibiting atp-utilizing enzyme inhibitory activity, and compositions, and uses thereof
MX2009006536A (es) Compuestos de heteroaril-heteroarilo como inhibidores de cdk para el tratamiento de cancer, inflamacion e infecciones virales.
TN2012000063A1 (en) Quinazolines as potassium ion channel inhibitors
EA200701396A1 (ru) Триазолофталазины в качестве ингибиторов pde-2
TW200740429A (en) Methods and dosage forms for reducing side effects of carbamate compounds
EP1667685A4 (en) INHIBITORS OF QUINAZOLINE-BASED POTASSIUM CANAL
TW200744567A (en) Phenylethylamine analogs and their use for treating glaucoma
EP1667976A4 (en) Isoquinolinone POTASSIUM CHANNEL INHIBITORS
WO2005117543A3 (en) N-sulfonylcarboximidamide apoptosis promoters
WO2006014877A3 (en) Potassium channel inhibitors
MX2007002917A (es) Todo-trans-retinol: todo-trans-13, 14-dihidrorretinol saturasa y metodos de uso de la misma.
WO2005030792A3 (en) Quinoline potassium channel inhibitors
WO2007077329A3 (fr) Nouvelle association d'un inhibiteur du courant if sinusoïdal et d'un inhibiteur calcique et les compositions pharmaceutiques qui la contiennent
MXPA06002315A (es) Abridores de canal erg para el tratamiento de arritmias cardiacas.