TW200605916A - Crystalline composition containing escitalopram - Google Patents
Crystalline composition containing escitalopramInfo
- Publication number
- TW200605916A TW200605916A TW094104639A TW94104639A TW200605916A TW 200605916 A TW200605916 A TW 200605916A TW 094104639 A TW094104639 A TW 094104639A TW 94104639 A TW94104639 A TW 94104639A TW 200605916 A TW200605916 A TW 200605916A
- Authority
- TW
- Taiwan
- Prior art keywords
- escitalopram
- crystalline particles
- composition containing
- escitalopram oxalate
- crystalline composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention discloses crystalline particles of escitalopram oxalate which either have a broad particle size distribution or comprise at least 0.01 % (w/w) of Z-4-(4-dimethylamino-1-(4-fluorophenyl)-but-1-enyl)-3-hydroxymethyl-benzonitrile, said particles being suitable for use in direct compression. Furthermore, the invention discloses a novel pharmaceutical unit dosage form containing such crystalline particles of escitalopram oxalate as well as methods for manufacture of such crystalline particles of escitalopram oxalate. Finally, the invention provides a method for reduction of the amount of hydroxyl containing impurities in a solution of citalopram or escitalopram.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200400382 | 2004-03-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200605916A true TW200605916A (en) | 2006-02-16 |
Family
ID=36607154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094104639A TW200605916A (en) | 2004-03-05 | 2005-02-17 | Crystalline composition containing escitalopram |
Country Status (9)
Country | Link |
---|---|
KR (1) | KR20060126587A (en) |
CN (3) | CN101492435A (en) |
AR (1) | AR047749A1 (en) |
IL (1) | IL177504A0 (en) |
MY (1) | MY142756A (en) |
PE (1) | PE20051162A1 (en) |
SG (1) | SG159504A1 (en) |
TW (1) | TW200605916A (en) |
ZA (1) | ZA200607382B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114763343A (en) * | 2021-01-14 | 2022-07-19 | 浙江华海药业股份有限公司 | Method for purifying citalopram or S-citalopram |
CN113663356B (en) * | 2021-08-23 | 2022-09-23 | 广西埃索凯新材料科技有限公司 | Crystallization impurity removal monitoring system applied to manganese sulfate production |
-
2005
- 2005-02-17 TW TW094104639A patent/TW200605916A/en unknown
- 2005-02-21 CN CNA2009100028557A patent/CN101492435A/en active Pending
- 2005-02-21 SG SG201000567-6A patent/SG159504A1/en unknown
- 2005-02-21 CN CNA2005800069400A patent/CN1925844A/en active Pending
- 2005-02-21 ZA ZA200607382A patent/ZA200607382B/en unknown
- 2005-02-21 KR KR1020067017907A patent/KR20060126587A/en not_active Application Discontinuation
- 2005-02-21 CN CNA2009100028561A patent/CN101492436A/en active Pending
- 2005-02-24 AR ARP050100683A patent/AR047749A1/en not_active Application Discontinuation
- 2005-03-02 PE PE2005000241A patent/PE20051162A1/en not_active Application Discontinuation
- 2005-03-03 MY MYPI20050870A patent/MY142756A/en unknown
-
2006
- 2006-08-15 IL IL177504A patent/IL177504A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
PE20051162A1 (en) | 2006-01-16 |
MY142756A (en) | 2010-12-31 |
ZA200607382B (en) | 2008-05-28 |
CN101492435A (en) | 2009-07-29 |
SG159504A1 (en) | 2010-03-30 |
CN1925844A (en) | 2007-03-07 |
KR20060126587A (en) | 2006-12-07 |
AR047749A1 (en) | 2006-02-15 |
CN101492436A (en) | 2009-07-29 |
IL177504A0 (en) | 2006-12-10 |
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