MY142756A - Crystalline composition containing escitalopram. - Google Patents

Crystalline composition containing escitalopram.

Info

Publication number
MY142756A
MY142756A MYPI20050870A MYPI20050870A MY142756A MY 142756 A MY142756 A MY 142756A MY PI20050870 A MYPI20050870 A MY PI20050870A MY PI20050870 A MYPI20050870 A MY PI20050870A MY 142756 A MY142756 A MY 142756A
Authority
MY
Malaysia
Prior art keywords
escitalopram
crystalline particles
composition containing
escitalopram oxalate
crystalline composition
Prior art date
Application number
MYPI20050870A
Inventor
Kim Boejstrup Jensen
Rikke Eva Humble
Ken Liljegren
Troels Volsgaard Christensen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of MY142756A publication Critical patent/MY142756A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Abstract

THE PRESENT INVENTION DISCLOSES CRYSTALLINE PARTICLES OF ESCITALOPRAM OXALATE WHICH EITHER HAVE A BROAD PARTICLE SIZE DISTRIBUTION OR COMPRISE AT LEAST 0.01 % (W/W) OF Z-4-(4-DIMETHYLAMINO-1 -(4-FLUOROPHENYL)-BUT-1 -ENYL)-3-HYDROXYMETHYL- BENZONITRILE, SAID PARTICLES BEING SUITABLE FOR USE IN DIRECT COMPRESSION. FURTHERMORE, THE INVENTION DISCLOSES A NOVEL PHARMACEUTICAL UNIT DOSAGE FORM CONTAINING SUCH CRYSTALLINE PARTICLES OF ESCITALOPRAM OXALATE AS WELL AS METHODS FOR MANUFACTURE OF SUCH CRYSTALLINE PARTICLES OF ESCITALOPRAM OXALATE FINALLY, THE INVENTION PROVIDES A METHOD FOR REDUCTION OF THE AMOUNT OF HYDROXYL CONTAINING IMPURITIES IN A SOLUTION OF CITALOPRAM OR ESCITALOPRAM.
MYPI20050870A 2004-03-05 2005-03-03 Crystalline composition containing escitalopram. MY142756A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200400382 2004-03-05

Publications (1)

Publication Number Publication Date
MY142756A true MY142756A (en) 2010-12-31

Family

ID=36607154

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20050870A MY142756A (en) 2004-03-05 2005-03-03 Crystalline composition containing escitalopram.

Country Status (9)

Country Link
KR (1) KR20060126587A (en)
CN (3) CN101492435A (en)
AR (1) AR047749A1 (en)
IL (1) IL177504A0 (en)
MY (1) MY142756A (en)
PE (1) PE20051162A1 (en)
SG (1) SG159504A1 (en)
TW (1) TW200605916A (en)
ZA (1) ZA200607382B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114763343A (en) * 2021-01-14 2022-07-19 浙江华海药业股份有限公司 Method for purifying citalopram or S-citalopram
CN113663356B (en) * 2021-08-23 2022-09-23 广西埃索凯新材料科技有限公司 Crystallization impurity removal monitoring system applied to manganese sulfate production

Also Published As

Publication number Publication date
TW200605916A (en) 2006-02-16
CN1925844A (en) 2007-03-07
ZA200607382B (en) 2008-05-28
CN101492435A (en) 2009-07-29
IL177504A0 (en) 2006-12-10
AR047749A1 (en) 2006-02-15
KR20060126587A (en) 2006-12-07
CN101492436A (en) 2009-07-29
SG159504A1 (en) 2010-03-30
PE20051162A1 (en) 2006-01-16

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