TW200537656A - Method and apparatus for low temperature sterilization and disinfections - Google Patents

Method and apparatus for low temperature sterilization and disinfections Download PDF

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TW200537656A
TW200537656A TW93112390A TW93112390A TW200537656A TW 200537656 A TW200537656 A TW 200537656A TW 93112390 A TW93112390 A TW 93112390A TW 93112390 A TW93112390 A TW 93112390A TW 200537656 A TW200537656 A TW 200537656A
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sterilization
disinfection
ozone
low
item
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TW93112390A
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TWI284543B (en
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Li-Xing Ding
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Li-Xing Ding
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  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

There is disclosed a method for the low temperature sterilization and disinfections to be applied to medical apparatus/instruments. By effective removal and destruction of contaminates, particularly living organisms, bacterial spores, virus, organics from used or contaminated medical apparatus/instruments surface, hollow tube, joints and crevices. Having greatest immediate application for the cleaning, sterilizing and disinfecting used or contaminated medical apparatus/instruments that are used to treat patients. The used or contaminated medical apparatus/instruments are immersed in an aqueous bath, which contains one or more disinfectant agents and the aqueous bath is circulated over the apparatus/instruments while ultrasonic vibration is applied to the aqueous bath to fast and effectively desorb the contaminates and living organisms from both inside and outside of the apparatus/instruments. The desorbed living organisms are washed out and killed by the circulating water stream containing disinfectants and decomposed by introducing ozone into the aqueous stream and, most preferably, while subjecting the ozonated water stream containing contaminates or microorganisms to ultraviolet radiation, thereby producing an apparatus/instrument which can be fast and efficiently cleaned, disinfected and sterilized all in one process.

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200537656 玖、發明說明: 【發明所屬之技術領域】 本發明係關於一種低溫消毒滅菌方法及其裝置,特別 是指一種不需在高溫高壓反應下,即可經由本技術之反應 達到完全除污、消毒、滅菌目的之低溫處理方法及其裝置。 【先前技術】 目前用於醫療院所中消毒醫療器材之方法最普遍亦最 有效者為高溫消毒法,然而受限於場地及操作條件之限® 制,有許多之醫療材無法使用南溫 > 肖毒法5以綠保醫療 過程之污染物及細菌病毒均被完全移除消滅,以致病患在 後續醫療過程中受到交互感染,造成生命財產之損失。 醫療界所稱之除污(Decontamination)包含了消毒、滅 菌,一般針對各種侵入式醫療器材之法規規定,大多要求 達到滅菌等級,然而對於許多構造複雜之不耐熱器材如昂φ 貴的内視鏡等,無法以常見之高溫滅菌法處理時,高級消 毒(99.9999%)亦是法規所能接受之替代方案。 除高溫滅菌法外,常見之替代消毒法以環氧乙烷(EO) 消毒較為有效,其主要用於醫療院所中構造單純之不耐熱 醫療器材。目前國際癌症研究總署(IARC)已將EO列為第 一級致癌因子,而暴露在此化學物之下,也可能導致°惡心、 嘔吐、皮膚燒傷或肺水腫等症狀;此外,研究亦顯示E〇 200537656 會造成流產與胎兒異常,或是增加胃癌、白血症、循環系 統疾病患者的死亡率。醫院中主要暴露者為消毒室中操作 EO消毒機的人員,另外,各單位使用滅菌後器材者,亦可 能暴露於殘留器材上並逐漸釋出的環氧乙烷。又若未在E〇 肩毋機所在處设計獨立之通風排氣設備,E〇的沈降特性可 能會滯留於工作場所中,引起多人的暴露。國際上為因應 %氧乙烧對使用者造成的潛在危害,正積極尋求替代的消 毒滅菌方式。 雖然目前可使用的低溫滅菌技術,除環氧乙烷外,尚有 離子束輻射滅菌法(Ionizing Radiation)、氣衆法(Gas Plasma)、或是使用氣相過氧化氫(Vapor Phase Hydrogen Peroxide)、臭氧(Ozone)、冰醋酸(Peracetic acid)與戊二搭 (glutaraldehyde)等化學物,然考量經濟成本、消毒效果、適 用物品種類後,環氧乙烷消毒法仍為最常被使用之方法。 ( 針對許多構造複雜之不耐熱器材如昂貴的内視鏡等,目 前常使用的低溫滅菌技術主要以液態反應為主,例如以冰 醋酸(Peracetic acid)或戊二酸(giutaraidehyde)等化學物質浸 泡内視鏡一段時間,並透過上述藥劑循環沖洗内視鏡管道 以達到接觸並消滅細菌及病毒之目的。然而國際醫療界普 遍面臨之問題為昂責的内視鏡具有複雜之設計,以致黏附 於孔隙、管道及接縫中之病毒無法經由化學藥劑沖洗而完 200537656 全去除消滅,甚至許多具抗藥性之細菌芽孢,可在惡劣環 境時進入冬眠狀態,一但惡劣環境消失,未清除之細菌即 可再恢復活性造成病患感染或死亡,以致清洗品質不佳、 交互感染、死亡案例時有所聞;且戊二醛等藥劑之時效性 與對操作人員之呼吸系統危害性均為操作時無法有效掌握 者0 由此可見,上述習用方法仍有諸多缺失,實非一良善之 設計,亟待加以改良。 1 本案發明人鑑於上述習用消毒滅菌方法所衍生的各項 缺點,乃亟思加以改良創新,並經多年潛心研究後,終於 成功研發完成本件低溫消毒滅菌方法及其裝置,不使用有 害操作人員之環氧乙烧(EO)、冰醋酸(Peracetic acid)或戊二 搭(glutaraldehyde),且可快速有效解決現行全球醫療界針對 昂貴且不耐高溫,而構造複雜之内視鏡、心導管等醫療器I 材之低溫消毒滅菌技術障礙。 【發明内容】 本發明之目的即在於提供一種針對無法進行高溫消毒 之醫療器材,如内視鏡、心導管、洗腎機等進行消毒滅菌 之處理,以達到除污、消毒、滅菌目的之處理方法及其裝 置。 本發明之次一目的係在於提供一種低溫消毒滅菌方法 200537656 及其裝置可應用於各種遭受細菌及病毒等污染之醫療器 材。 本發明之另一目的係在於提供一種可替代高溫消毒法 的快速有效消毒滅菌技術,此低溫消毒滅菌方法及其裝置 可應用於各種設計複雜或不耐高溫之醫療器材。 【技術内容】 可達成上述發明目的之低溫消毒滅菌方法及其裝置,主 要係將各種醫療器材,如手術剪、刀、夾及昂貴複雜之内· 視鏡、心導管、洗腎機等受污染之醫療器材置入一内含超 音波、紫外線、臭氧以及消毒液的反應系統,透過超音波 震盪可將各種醫療器材表面、空心管、接縫和裂缝内之細 菌芽孢、病毒或者污染物有效脫附去除,然後再以臭氧之 強大氧化破壞能力,將脫附去除之細菌芽孢、病毒或者有 機污染物氧化破壞,同時結合紫外線的殺菌力,可行成光 催化反應提升反應效率,加速臭氧氧化破壞進行;同時,® 消毒液也在此時與脫附之細菌芽孢、病毒或者污染物接觸 並將之消滅破壞,以達到最終之消毒滅菌目標。 許多侵入式之醫療器材接觸過人體後,將黏附病人之污 染物如:體液、血液、病菌、病毒等。依過去經驗顯示, 此種污染物黏附力甚強,若無適當之除污方式,甚難將污 染物完全而徹底消滅,因此,使用超音波震盪之主要目的, 8 200537656 乃透過其強Λ之震盪力(Cavitations)可將各種醫療器材表 面、空心管、接縫和裂縫内之細菌芽孢、病毒或者污染物 有效脫附去除,所使用之超音波頻率自1〜200,000KHz,其 強度足以將小至0.12微米孔隙内之污染物震盪脫附出醫療 器材,並與系統中之其他單元進行反應。 本系統之臭氧係將空氣或純氧通過一臭氧產生器後,製 造出雨濃度臭氧,再經過輸送系統及曝氣裝置導入反應槽 底部,與水溶液充分混合形成飽和臭氧水(〇zonate(^ water),經超音波脫附之污染物與水溶液中之飽和臭氧接觸 後,立即進行氧化破壞分解反應,而人體之污染物均為碳 水化合物,經臭氧分解後可行成無害之二氧化碳及水,達 到除污消毒之效果。 紫外線為一具有強大而廉價特性之消毒工具,可將細菌 或病毒有效地消滅,本系統之紫外線頻率為1〇〇〜390 nanometer (1000〜3900 Angstroms),反應槽在紫外線照射下春 形成一無菌狀態,可防止外界空氣中之細菌病毒與醫療器 材接觸造成再感染(Recontamination);而臭氧在紫外線照射 下,亦f行成光化學催化反應,加速污染物之破壞分解速 率,有助於消毒滅菌反應之進行。 本系統之水溶液中加有化學藥劑,經由幫浦將其自化 學藥劑槽輸送至反應槽中,透過與脫咐之細菌病毒接觸反 200537656 應,化學藥劑可迅速將其殺死,而達到消毒滅菌之目的。 上述之化學藥劑係指一般常見之液體消毒劑或滅菌劑如: 過氧化氫(Hydrogen Peroxide)、鹽酸(Hydrochloric acid)、硫 酸(Sulfuric acid)與次氣酸(Hypochlorite)等均可適用,操 作濃度範圍為10〜200,000ppm。 【圖式簡單說明】 請參閱以下有關本發明一較佳實施例之詳細說明及其 附圖,將可進一步瞭解本發明之技術内容及其目的功效;# 有關該貫施例之附圖為· 圖一為本發明低溫诮毒滅菌方法及其裝置之架構圖。 【主要部分代表符號】 1 反應槽 11 進水電磁閥 12 排水電磁閥 13 活性碳過濾灌 2 臭氧產生器 21 曝氣管 3 紫外線燈管 4 超音波產生器 5 藥劑輸送幫浦 51 消毒/滅菌藥劑槽 200537656 52 反應藥液循環幫浦 【較佳實施例】 請參閱圖一所示,本發明所提供之低溫消毒滅菌方法及 其裝置之架構圖,其係針對各種設計複雜或不耐高溫之醫 療器材進行消毒滅菌處理,主要包含有: 一反應槽裝置1,該反應槽裝置1可供醫療器材置入並 進行消毒滅菌處理反應; 一臭氧產生裝置2,可將空氣或純氧通過此產生裝置修 後,提供具強大氧化能力之臭氧,於液中針對醫療器材之 污染物質進行消毒殺菌處理; 一紫外線殺菌裝置3,包含紫外線燈設備為主,其波長 自100至390nm,亦可加裝光觸媒Ti02裝置,當紫外線與 臭氧接觸反應時,可行成光催化反應,使本技術方法之氣 態及液態氧化反應速率大幅提昇,可快速反應分解破壞殘 餘之污染物或病S ; ® 一超音波產生器裝置4,可提供自1〜200,000KHz之頻 率,可裝置於反應槽1外部或以反應棒之方式置入反應槽1 内部,槽内填入水溶液其液面並超過醫療器材,超音波裝 置產生之震盪力足可將微小縫隙中之污染物脫附出醫療器 材; 一消毒/滅菌藥劑供應裝置5,其包含消毒/滅菌藥劑槽 200537656 及輸送桌浦,可將藥劑輸入反應槽,並依指定藥劑濃度混 合稀釋為10至2〇〇,〇〇〇卯m之濃度,可有效與脫附之污染 物或病菌接觸反應,達到消毒殺菌之目的。 本系統之反應槽1内裝置有超音波裝置,可將附著於各 種醫療器材表面、空心管、孔隙和裂缝内之細菌芽孢、病 毒或者污染物快速有效脫附去除,脫附功率可滲透至小到 0.12微米之孔隙;同時,反應藥劑槽5内裝有一種或一種 以上之強力化學藥劑與美國食品藥物管理局(FDA)認% 之/肖毋/#又鹵某劑【如次氯酸納(只外〇(^1〇1·^ )、過氧化氫 (Η2〇2)、硫酸(Sulfuricacid)等】,並透過反應藥液循環 幫浦52稀釋後與醫療器材接觸使其可有效消滅被超音波震 蘯脫附之細菌及病毒,同時與溶解於水溶液中之強力氧化 劑臭氧2接觸,可將有機污染物氧化分解,以進行消毒殺 菌反應,並可經過紫外線、光觸媒及域之反應將少量殘 餘未反應完全之污染物在光催化反應下,進行快速分解一 菌反應,以確保無殘餘污染物或病毒存在於醫療器材之表 面甚至是管路内部微小之孔隙中。 最後和之臭氧氣體將伴隨上升至反應槽工之上 β ’並與i外絲成—無菌空間,以確保在消毒滅菌過程 中’不致因外界氣體及水f傳輸而造成醫療器材二次污染。 【特點及功效】 12 200537656 本發明所提供之低溫消毒滅菌方法及其裝置,與其他習 用技術相互比較時,更具有下列之優點: 1. 本發明可取代高溫消毒滅菌法,提供醫療器材於常溫常 壓下即可進行除污、消毒、殺菌之技術。 2. 本發明係可提供快速脫附處理之功能,可針對附著於醫 療器材孔隙内之有機污染物、細菌、病毒等,使其無法 黏附,以達到清潔除污之效果。 3. 本發明可針對受污染之醫療器材之表面甚至是管路内鲁 部微小至0.12微米之孔隙中進行處理,以達到除污、 消毒、殺菌之目的。 4. 本發明提供數道安全防護設計,當高濃度污染物或病毒 黏附時,仍設計有多重不同之反應裝置,結合超音波、 紫外線、臭氧及消毒劑之強大氧化分解功能,可以有效 破壞消滅病毒或污染物,以達到除污、消毒、殺菌之目 的。 · 5. 本發明提供一無菌反應空間,包含反應槽之氣相與液相 均達無菌狀態,可避免醫療器材於消毒作業時遭受二次 污染。 6. 本發明與醫療器材之材質具有相容性,不會造成儀器損 壞之情形發生。 7. 本發明所使用之消毒滅菌劑為稀釋後之低濃度無害藥 13 200537656 劑,反應過程對於環境及操作人員均不致造成危害,使 用後亦可直接排放,無二次污染之問題。 上列詳細說明係針對本發明之一可行實施例之具體說 明,惟該實施例並非用以限制本發明之專利範圍,凡未脫 離本發明技術精神所為之等效實施或變更,均應包含於本 案之專利範圍中。 綜上所述,本案不但在技術思想上確屬創新,且經證實 具有低溫下消毒殺菌之功效,並能較習用物品增進上述多籲 項功效,尤其針對目前低溫消毒法均以浸泡藥水方式處 理,時間較久,品質不佳,且尚無法充分有效去除複雜儀 器孔隙中之微小病毒,故本技術應已充分符合新穎性及進 步性之法定發明專利要件,爰依法提出申請,懇請貴局 核准本件發明專利申請案,以勵發明,至感德便。200537656 发明 Description of the invention: [Technical field to which the invention belongs] The present invention relates to a low-temperature sterilization method and device, particularly to a method for completely decontamination through the reaction of this technology without the need for high-temperature and high-pressure reactions. Low-temperature treatment method and device for disinfection and sterilization purposes. [Previous technology] Currently, the most common and most effective method for disinfecting medical equipment in medical institutions is the high temperature disinfection method. However, due to the limitations of the site and operating conditions®, many medical materials cannot be used. ; Xiao poison method 5 The pollutants and bacterial viruses in the green protection medical process are completely removed and eliminated, resulting in the patient being cross-infected in the subsequent medical process, causing loss of life and property. Decontamination in the medical field includes disinfection and sterilization. Generally, the regulations for various invasive medical devices generally require sterilization. However, for many heat-resistant equipment with complex structures such as expensive endoscopes, When it cannot be processed by common high-temperature sterilization methods, advanced disinfection (99.9999%) is also an acceptable alternative to regulations. In addition to high temperature sterilization, common alternative disinfection methods are more effective with ethylene oxide (EO) disinfection, which is mainly used in medical institutions to construct simple heat-resistant medical equipment. At present, the International Agency for Research on Cancer (IARC) has listed EO as a first-class carcinogen, and exposure to this chemical may also cause symptoms such as nausea, vomiting, skin burns, or pulmonary edema; in addition, research has also It has been shown that E〇200537656 can cause abortion and fetal abnormalities, or increase the mortality of patients with gastric cancer, white blood disease, and circulatory diseases. The main exposed persons in the hospital are those who operate the EO disinfection machine in the disinfection room. In addition, those who use the sterilized equipment in each unit may also be exposed to the residual equipment and gradually release ethylene oxide. If an independent ventilation and exhaust device is not designed where the E0 shoulder machine is located, the sedimentation characteristics of E0 may stay in the workplace and cause exposure of many people. Internationally, in response to the potential harm to users caused by% oxyethane, we are actively seeking alternative methods of disinfection and sterilization. Although currently available low-temperature sterilization technologies, in addition to ethylene oxide, there are still ion beam radiation sterilization (Ionizing Radiation), Gas Plasma, or Vapor Phase Hydrogen Peroxide. , Ozone (Ozone), Peracetic acid and glutaraldehyde, etc. However, after considering the economic cost, disinfection effect, and types of applicable items, the ethylene oxide disinfection method is still the most commonly used method . (For many heat-resistant equipment with complicated structures, such as expensive endoscopes, the low-temperature sterilization technology currently used is mainly liquid reaction, such as immersion in chemicals such as Peracetic acid or giutaraidehyde Endoscopes are flushed for a period of time and the endoscope tubes are flushed through the above-mentioned medicaments to achieve the purpose of contacting and destroying bacteria and viruses. However, the problem commonly faced by the international medical community is that the responsible endoscopes have a complex design and cause adhesion to Viruses in pores, pipes, and joints cannot be washed away by chemical agents. 200537656 Complete removal and elimination, even many drug-resistant bacterial spores can enter hibernation in harsh environments. Once the harsh environment disappears, the unremoved bacteria are The resumption of activity can cause infection or death of patients, resulting in poor cleaning quality, cross infection, and death cases; and the timeliness of glutaraldehyde and other agents and the harm to the respiratory system of the operator are impossible during operation. Effective master 0 It can be seen that there are still many shortcomings in the above conventional methods, which is not a good design. Immediate improvements are needed. 1 In view of the various shortcomings derived from the conventional disinfection and sterilization methods, the inventor of this case was eager to improve and innovate. After years of intensive research, he finally successfully developed and completed this low-temperature disinfection and sterilization method and device. Ethylene oxide (EO), Peracetic acid, or glutaraldehyde, which are harmful to operators, can quickly and effectively solve the current global medical industry's complex endoscopes that are expensive and not resistant to high temperatures, Technical obstacles to low-temperature disinfection and sterilization of medical instruments such as cardiac catheters. [Summary of the invention] The purpose of the present invention is to provide a medical instrument that cannot be sterilized at high temperature, such as endoscopes, cardiac catheters, and kidney dialysis machines. Treatment method and device for decontamination, disinfection and sterilization, and a second purpose of the present invention is to provide a low-temperature sterilization and sterilization method 200537656 and the device can be applied to various medical equipments contaminated by bacteria and viruses. Another object of the present invention is to provide a rapid and rapid alternative to high temperature disinfection. Effective disinfection and sterilization technology, this low-temperature disinfection and sterilization method and device can be applied to various medical devices with complex designs or high temperature resistance. [Technical content] The low-temperature disinfection and sterilization method and device that can achieve the above-mentioned purpose of the invention are mainly used for various medical treatments. Equipment, such as surgical scissors, knives, clips, and expensive and complex equipment. · Contaminated medical equipment such as sight glass, cardiac catheter, and kidney dialysis machine are placed in a reaction system containing ultrasound, ultraviolet, ozone, and disinfectant. Sonic vibration can effectively desorb and remove bacterial spores, viruses or pollutants from the surface of various medical equipment, hollow tubes, joints and cracks, and then use the strong oxidative destruction capacity of ozone to remove bacterial spores, viruses, or The oxidative destruction of organic pollutants, combined with the germicidal power of ultraviolet rays, can be a photocatalytic reaction to improve the reaction efficiency and accelerate the oxidative ozone destruction. At the same time, the disinfectant is in contact with the desorbed bacterial spores, viruses or pollutants at this time and It will be destroyed to achieve the final sterilization goal. Many invasive medical devices will contact the patient's pollutants such as body fluids, blood, germs, and viruses after contacting the human body. According to past experience, this kind of pollutant has a very strong adhesion. It is very difficult to completely and completely eliminate the pollutant without proper decontamination methods. Therefore, the main purpose of using ultrasonic vibration is through its strong Λ Cavitations can effectively desorb and remove bacterial spores, viruses or pollutants in the surface of various medical equipment, hollow tubes, joints and cracks. The ultrasonic frequency used is from 1 ~ 200,000KHz, and its strength is sufficient to reduce Contaminants in the pores to 0.12 micron oscillate to desorb the medical device and react with other units in the system. The ozone of this system passes air or pure oxygen through an ozone generator to produce rain-concentrated ozone, which is then introduced into the bottom of the reaction tank through the conveying system and aeration device, and is fully mixed with the aqueous solution to form saturated ozone water (〇zonate (^ water ), The pollutants desorbed by ultrasound and the saturated ozone in the aqueous solution immediately contact the oxidative destruction and decomposition reaction, while the pollutants in the human body are all carbohydrates, which can be decomposed into harmless carbon dioxide and water after ozone decomposition to achieve removal The effect of disinfection of pollution. Ultraviolet is a powerful and cheap disinfection tool that can effectively eliminate bacteria or viruses. The ultraviolet frequency of this system is 100 ~ 390 nanometer (1000 ~ 3900 Angstroms). The reaction tank is exposed to ultraviolet rays. A sterile state will be formed in the spring, which can prevent the infection of bacteria and viruses in the outside air with medical equipment to cause recontamination. Under the irradiation of ultraviolet rays, ozone also forms a photochemical catalytic reaction, which accelerates the destruction and decomposition rate of pollutants. Helps to carry out the disinfection and sterilization reaction. Chemicals are added to the aqueous solution of this system The pump is transported from the chemical tank to the reaction tank through the pump, and through contact with the bacterial virus, the reaction can be quickly killed, and the purpose of disinfection and sterilization is achieved. The above chemical agents refer to general Common liquid disinfectants or sterilants such as: Hydrogen Peroxide, Hydrochloric acid, Sulfuric acid, and Hypochlorite are applicable. The operating concentration range is 10 ~ 200,000 ppm. [Brief description of the drawings] Please refer to the following detailed description of a preferred embodiment of the present invention and the accompanying drawings, which will further understand the technical content of the present invention and its purpose and effect; # The accompanying drawings are: Figure 1 is the structural diagram of the low-temperature poisonous sterilization method and device of the present invention. [Representative symbols of main parts] 1 Reaction tank 11 Water inlet solenoid valve 12 Water discharge solenoid valve 13 Activated carbon filter irrigation 2 Ozone generator 21 Aeration tube 3 Ultraviolet rays Lamp tube 4 Ultrasonic generator 5 Medicine delivery pump 51 Disinfection / sterilization medicine tank 200537656 52 Reactive medicine liquid circulation pump [preferred embodiment] Referring to FIG. 1, the structural diagram of the low-temperature sterilization method and the device provided by the present invention is for sterilizing and treating various medical equipment with complex design or high temperature resistance. It mainly includes: a reaction tank device 1, The reaction tank device 1 can be used for medical equipment to be placed and sterilized and sterilized. An ozone generating device 2 can repair air or pure oxygen through the generating device to provide ozone with strong oxidation ability. The pollutants of the equipment are disinfected and sterilized. A UV sterilization device 3, which contains UV light equipment, has a wavelength from 100 to 390 nm. A photocatalytic Ti02 device can also be installed. When UV and ozone contact and react, it can become a photocatalytic reaction. The gaseous and liquid oxidation reaction rate of this technical method is greatly improved, and the remaining pollutants or diseases can be quickly decomposed and broken down. ® An ultrasonic generator device 4, which can provide a frequency from 1 ~ 200,000KHz, can be installed in The reaction tank 1 is placed outside or inside the reaction tank 1 in the form of a reaction rod, and the tank is filled with an aqueous solution whose level exceeds The vibration force generated by the equipment and the ultrasonic device is enough to desorb the pollutants in the tiny gaps out of the medical equipment; a disinfection / sterilization agent supply device 5, which includes a disinfection / sterilization agent tank 200537656 and a delivery table pump, which can input the medicine The reaction tank is mixed and diluted to a concentration of 10 to 200,000 μm according to the concentration of the specified agent, which can effectively contact and react with desorbed pollutants or germs to achieve the purpose of disinfection. Ultrasonic device is installed in the reaction tank 1 of the system, which can quickly and effectively desorb and remove bacterial spores, viruses or pollutants attached to the surface of various medical equipment, hollow tubes, pores and cracks, and the desorption power can penetrate to a small To 0.12 micron pores; at the same time, one or more powerful chemicals are contained in the reaction agent tank 5 and the US Food and Drug Administration (FDA) recognizes that / xiao Wu / # Another halogen [such as sodium hypochlorite (Only 〇 (^ 1〇1 · ^), hydrogen peroxide (Η202), sulfuric acid (Sulfuricacid), etc.], and through the reaction liquid circulation pump 52 diluted with contact with medical equipment so that it can effectively eliminate Ultrasonic vibration desorbs bacteria and viruses, and at the same time contacts with the strong oxidant ozone 2 dissolved in aqueous solution, it can oxidize and decompose organic pollutants for disinfection and sterilization reaction. Residual unreacted pollutants undergo a rapid decomposition-bacteria reaction under a photocatalytic reaction to ensure that no residual pollutants or viruses are present on the surface of the medical device or even inside the pipeline. In the pores, the final ozone gas will rise to the top of the reaction tank β ′ and form a sterile space with the outer filament of i, to ensure that during the sterilization process, “the medical equipment will not be caused by the transmission of external gas and water f. [Characteristics and efficacy] 12 200537656 The low-temperature sterilization method and device provided by the present invention have the following advantages when compared with other conventional technologies: 1. The present invention can replace the high-temperature sterilization method and provide medical treatment. The equipment can perform decontamination, disinfection and sterilization technology at normal temperature and pressure. 2. The invention can provide the function of rapid desorption treatment, which can target organic pollutants, bacteria, viruses, etc. attached to the pores of medical equipment. It can not be adhered to achieve the effect of cleaning and decontamination. 3. The invention can treat the surface of the contaminated medical equipment or even the pores as small as 0.12 micrometers in the pipeline to achieve decontamination, disinfection, The purpose of sterilization 4. The present invention provides several safety protection designs, when high concentrations of pollutants or viruses adhere, there are still multiple different designs The device, combined with the powerful oxidative decomposition function of ultrasound, ultraviolet, ozone and disinfectant, can effectively destroy and eliminate viruses or pollutants to achieve the purpose of decontamination, disinfection and sterilization. 5. The present invention provides a sterile reaction space, Both the gas phase and the liquid phase containing the reaction tank are sterile, which can prevent secondary pollution of medical equipment during sterilization. 6. The material of the invention is compatible with the material of the medical equipment and will not cause damage to the instrument. 7. The disinfection and sterilant used in the present invention is a diluted low-concentration innocuous agent 13 200537656. The reaction process does not cause harm to the environment and operators, and can be directly discharged after use without the problem of secondary pollution. The detailed description is a specific description of a feasible embodiment of the present invention, but this embodiment is not intended to limit the patent scope of the present invention. Any equivalent implementation or change that does not depart from the technical spirit of the present invention should be included in this case. Patent scope. To sum up, this case is not only technically innovative, but also proved to have the effect of disinfection and sterilization at low temperature, and can enhance the above-mentioned multiple effects compared with conventional items, especially for the current low-temperature disinfection methods are treated by soaking syrup. , Time is long, the quality is not good, and the tiny virus in the pores of complex instruments cannot be effectively removed, so this technology should have fully met the novel and progressive statutory invention patent requirements, apply according to law, and ask your office for approval This invention patent application is designed to encourage inventions, to the utmost convenience.

1414

Claims (1)

200537656 拾、申請專利範圍: 1 · -種低溫消毒減菌方法及其I置,主要係將九 材置入本消毒滅菌 ,、、又,可木之醫療器 可將附著於久 ,透過本方法之超音波裝置, 子附者於各種複雜醫療器材 之細菌芽孢、病主㈣、1此 工5孔隙和裂縫内 或者❻物快速有效贿去除;同時,醫 解於水溶液中之強力氧化劑臭氧接觸,可 :木物乳化分解’以進行消毒殺菌反應,並可經過紫外線、、 光觸媒及臭氧之反應將少量殘餘未反應完全之污染物在 催化反應下’進行快速分解㈣反應,㈣保㈣餘污染物 或病母存在於醫療器材之表面甚至是管路内部微小之孔隙 中。同時,反應藥劑槽内裝有一種或一種以上之強力化學藥 劑與美國食品藥物管理局(FDA)認可之消毒/殺菌藥劑【如 次氯酸鈉(Hypochlorite)、過氧化氫(H2〇2)、硫酸(Sulfuric acid)等】’並透過反應藥液循環幫浦與醫療器材接觸使其可 有政消滅被超音波震盛脫附之細菌及病毒;最後,過飽和之I 臭氧氣體將伴隨上升至反應槽1之上部,並與紫外線形成一 無菌空間,以確保在消毒滅菌過程中,不致因外界氣體及水 質傳輪而造成醫療器材二次污染。 2·如申請專利範圍第1項所述之低溫消毒滅菌方法,其中該超 音波震盪方法可將附著於微小孔隙内之污染物及細菌、病毒 力口以震盪脫附,以達到除污清潔之目的。 15 200537656 3·如申請專利範圍第1項所述之低溫消毒滅菌方法,其中該氧 化反應方法為一臭氧反應系統,可將空氣或純氧反應成臭 氧,經由輸氣幫浦透過曝氣管與反應槽之水溶液混合產生飽 和臭氧水(Ozonated Water),使污染物能充份與臭氧水接觸 反應,以達到氧化殺菌之目的。 4·如申請專利範圍第1項所述之低溫消毒滅菌方法,其中紫外 線裝置與臭氧結合之光化學反應速率遠大於單純臭氧數十 至數百倍,使其可快速反應氧化殘餘污染物或病菌。 φ 5·如申請專利範圍第1項所述之低溫消毒滅菌方法,其中該氧 化槽内可設置紫外線燈。 6. 如申請專利範圍第1項所述之低溫消毒滅菌方法,其中該氧 化槽内可設置臭氧。 7. 如申請專利範圍第1項所述之低溫消毒滅菌方法,其中該氧 化槽内可設置光觸媒(Ti02)。 8. 如申請專利範圍第1項所述之低溫消毒滅菌方法,其中該 化槽内可設置紫外線燈、光觸媒(Ti02)及臭氧。 9. 如申請專利範圍第2項所述之低溫消毒滅菌方法,其中該超 音波裝置之頻率可為1〜200,000KHz。 10. 如申請專利範圍第3項所述之低溫消毒滅菌方法,其中該 臭氧裝置可為高壓放電或是紫外線臭氧產生法,可製造高濃 度臭氧以供反應所需。 16 200537656 ιι·如申請專利範圍第丨項所述之低溫料鞋方法,其中該 並可依需要調配適當 =學樂劑裝置可為—種或多種混合之消毒滅㈣,該化學藥 背J可有效消滅各種頑強之細菌病毒,並 濃度與藥劑。 12· 一種低溫消毒滅菌方法,至少包括: i.一反應槽裝置,其可將受污染之醫療器材置入進行消毒 滅菌處理; ϋ·一超音波裝置,其可有效脫料為、々、、九龄士 J负双脫附冗巧染醫療器材孔隙内 微小細菌與病毒; in.-氧化槽裝置,其包含紫外線或光觸媒或臭氧等氧化反 應裝置; w化學f縣置,其㈣有強力料/殺菌_,並於其 中設有輸送幫浦’可稀釋入反應槽内以對污染物進行 反應處理’確保污染物與消毒/殺菌藥劑及強氧化劑 元王接觸,進而將其氧化破壞。 13·如申請專利範圍第i項所述之低溫消毒滅菌裝置,其中該< 反應槽裝置可將受污染之醫療器材置入裝置中,以進行除 污、消毒、殺菌反應處理。 14·如申請專利範圍第!項所述之低溫消毒滅菌裝置,其中該 氧化槽内可設置紫外線燈及臭氧。 15·如申請專利範圍第1項所述之低溫消毒滅菌裝置,其中該 氣態氧化裝置可設置紫外線燈。 17 200537656 16. 如申請專利範圍第1項所述之低溫消毒滅菌裝置,其中該 氧化槽内可設置臭氧系統,包含有臭氧產生器、幫浦及曝氣 管。 17. 如申請專利範圍第1項所述之低溫消毒滅菌裝置,其中該 氧化槽内可設置光觸媒(Ti02)。 18. 如申請專利範圍第1項所述之低溫消毒滅菌裝置,其中該 氧化槽之光催化反應可快速反應氧化殘餘污染物或病菌。 19. 如申請專利範圍第1項所述之低溫消毒滅菌裝置,其中% 化學藥劑裝置,其内填有一種或多種混合之強力消毒/殺菌 藥劑,並設有輸送幫浦,可稀釋入反應槽内以對污染物進行 反應處理,確保污染物與消毒/殺菌藥劑及強氧化劑完全接 . 觸,進而將其氧化破壞。 . 20. 如申請專利範圍第12項所述之低溫消毒滅菌裝置,其中該 裝置為一高效率快速除污消毒滅菌處理裝置,該裝置可在常 溫下將醫療器材之細菌芽孢、病毒及污染物完全消滅。 癱 18200537656 The scope of patent application: 1 ·-a kind of low-temperature disinfection and sterilization method and its I device, mainly by putting nine materials into this disinfection and sterilization, and, can be attached to the medical device for a long time, through this method Ultrasound device, which can be quickly and effectively removed from bacterial spores, pathogens, pores and cracks in various medical equipment, and pores and cracks; and at the same time, the strong oxidant in the aqueous solution is contacted with ozone. Can: Emulsion decomposition of wood for disinfection and sterilization, and a small amount of residual unreacted pollutants can be quickly decomposed under the catalytic reaction through the reaction of ultraviolet rays, photocatalysts and ozone to protect the remaining pollutants. Or the sick mother exists on the surface of the medical equipment or even in the tiny pores inside the pipeline. At the same time, one or more powerful chemicals and sterilizing / sterilizing agents approved by the US Food and Drug Administration (such as Hypochlorite, hydrogen peroxide (H202), sulfuric acid (Sulfuric) acid) etc.] and contact the medical equipment through the circulation of the reaction liquid to make it possible to eliminate the bacteria and viruses desorbed by the ultrasonic shock; finally, the supersaturated I ozone gas will rise to the reaction tank 1 The upper part forms a sterile space with ultraviolet rays to ensure that during the disinfection and sterilization process, secondary pollution of medical equipment due to external gas and water transfer wheels will not be caused. 2. The method of low-temperature disinfection and sterilization according to item 1 of the scope of the patent application, wherein the ultrasonic vibration method can decontaminate pollutants, bacteria, and viruses attached to the tiny pores by vibration to achieve decontamination and cleanliness. purpose. 15 200537656 3. The low-temperature disinfection and sterilization method described in item 1 of the scope of the patent application, wherein the oxidation reaction method is an ozone reaction system, which can react air or pure oxygen into ozone, which is transmitted through the aeration pipe through the aeration pipe and the aeration pipe. The aqueous solution of the reaction tank is mixed to produce saturated ozone water, so that the pollutants can fully contact and react with the ozone water to achieve the purpose of oxidative sterilization. 4. The method of low-temperature disinfection and sterilization according to item 1 of the scope of the patent application, wherein the photochemical reaction rate of the ultraviolet device combined with ozone is much higher than that of simple ozone by dozens to hundreds of times, so that it can quickly react to oxidize residual pollutants or bacteria. . φ5. The low-temperature disinfection and sterilization method according to item 1 of the scope of patent application, wherein an ultraviolet lamp can be installed in the oxidation tank. 6. The method of low-temperature sterilization and sterilization according to item 1 of the scope of patent application, wherein ozone can be set in the oxidation tank. 7. The method of low-temperature sterilization and sterilization according to item 1 of the scope of patent application, wherein a photocatalyst (Ti02) can be set in the oxidation tank. 8. The low-temperature sterilization and sterilization method according to item 1 of the scope of patent application, wherein the chemical tank can be provided with an ultraviolet lamp, a photocatalyst (Ti02) and ozone. 9. The low-temperature disinfection and sterilization method according to item 2 of the scope of the patent application, wherein the frequency of the ultrasonic device can be 1 ~ 200,000KHz. 10. The low-temperature sterilization and sterilization method according to item 3 of the patent application scope, wherein the ozone device can be a high-pressure discharge or ultraviolet ozone generation method, and can produce high-concentration ozone for reaction needs. 16 200537656 ι · The method of low-temperature material shoes as described in item 丨 of the scope of application patent, which can be adjusted as required = Xuele agent device can be one or more mixed disinfection and disinfection methods. Effectively eliminate various stubborn bacterial viruses, and concentration and agents. 12. A method of low-temperature sterilization and sterilization, including at least: i. A reaction tank device that can put contaminated medical equipment for sterilization and sterilization treatment; ϋ an ultrasonic device that can effectively discharge materials, Nine-year-olds J negative double desorption and detrimental staining of tiny bacteria and viruses in the pores of medical equipment; in.-oxidation tank device, which contains oxidation reaction devices such as ultraviolet or photocatalyst or ozone; w chemical f county, which has strong materials / Sterilization_, and equipped with a transport pump 'can be diluted into the reaction tank to react on the pollutants' to ensure that the pollutants come into contact with the disinfection / sterilization agent and strong oxidant Yuan, and then oxidize and destroy them. 13. The low-temperature sterilization and sterilization device as described in item i of the scope of patent application, wherein the < reaction tank device can put contaminated medical equipment into the device for decontamination, disinfection, and sterilization reaction treatment. 14 · If the scope of patent application is the first! The low-temperature disinfection and sterilization device according to the item, wherein the oxidation tank can be provided with an ultraviolet lamp and ozone. 15. The low-temperature disinfection and sterilization device according to item 1 of the scope of the patent application, wherein the gaseous oxidation device can be provided with an ultraviolet lamp. 17 200537656 16. The low-temperature disinfection and sterilization device described in item 1 of the scope of patent application, wherein an ozone system can be set in the oxidation tank, including an ozone generator, a pump, and an aeration tube. 17. The low-temperature sterilization and sterilization device according to item 1 of the scope of patent application, wherein a photocatalyst (Ti02) can be set in the oxidation tank. 18. The low-temperature sterilization and sterilization device according to item 1 of the scope of the patent application, wherein the photocatalytic reaction of the oxidation tank can quickly react to oxidize residual pollutants or germs. 19. The low-temperature sterilization and sterilization device as described in item 1 of the scope of patent application, in which the% chemical agent device is filled with one or more mixed powerful disinfection / sterilization agents, and is equipped with a conveying pump, which can be diluted into the reaction tank. The internal treatment of the pollutants ensures that the pollutants are in complete contact with the disinfection / sterilization agent and strong oxidants, and then oxidized and destroyed. 20. The low-temperature sterilization and sterilization device according to item 12 of the scope of the patent application, wherein the device is a high-efficiency rapid decontamination, sterilization and sterilization treatment device, which can remove bacterial spores, viruses and pollutants of medical equipment at room temperature. Completely eliminated. Paralysis 18
TW93112390A 2004-05-03 2004-05-03 Method and apparatus for low temperature sterilization and disinfections TWI284543B (en)

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CN107986545A (en) * 2018-01-22 2018-05-04 过嘉明 Haemodialysis control unit wastewater treatment equipment
WO2023000186A1 (en) * 2021-07-21 2023-01-26 苏州涂泰克医疗器械有限公司 Disinfection device for use in production of medical instruments

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WO2020141359A1 (en) * 2019-02-12 2020-07-09 Mohammadi Khoshbakht Majid Super-fast sterilizer device for medical equipment with advanced oxidation process (aop) technology

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Publication number Priority date Publication date Assignee Title
CN107986545A (en) * 2018-01-22 2018-05-04 过嘉明 Haemodialysis control unit wastewater treatment equipment
WO2023000186A1 (en) * 2021-07-21 2023-01-26 苏州涂泰克医疗器械有限公司 Disinfection device for use in production of medical instruments

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