CN1961964A - Hypothermia sterilization method and apparatus thereof - Google Patents

Hypothermia sterilization method and apparatus thereof Download PDF

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Publication number
CN1961964A
CN1961964A CN 200510119836 CN200510119836A CN1961964A CN 1961964 A CN1961964 A CN 1961964A CN 200510119836 CN200510119836 CN 200510119836 CN 200510119836 A CN200510119836 A CN 200510119836A CN 1961964 A CN1961964 A CN 1961964A
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sterilization
reaction
medical device
reactive tank
ozone
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丁力行
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Abstract

The invention relates to a low-temperature disinfection method and relative device, wherein it can disinfect the polluted tools and medical device. It uses ultrasonic wave, ultraviolet and ozone, with the disinfection agent in water solution to clean and disinfect the tools. The invention has wide application.

Description

Cold sterilization sterilizing methods and device thereof
Technical field
The present invention relates to a kind of method for disinfection and sterilization and device thereof.
Background technology
Be used at present that the method for medical institutes sterilization medical device is the most general also the most effective to be the high-temperature sterilization method, yet be subject to the restriction of place and operating condition, there are many medical devices can't use the high-temperature sterilization method to guarantee that pollutant and bacterial virus in the medical procedure are all removed elimination fully, so that sufferer is subjected to aleopation in the subsequent medical process, cause the loss of lives and properties.
The alleged scrubbing (Decontamination) of medical profession has comprised sterilization, sterilization, general rules and regulations at various intrusive mood medical devices, require to reach the sterilization grade mostly, yet for the thermo-labile equipment of many complex structures such as the endoscope of costliness etc., in the time of can't handling with common high temperature sterilization, senior sterilization (99.9999%) also is the receptible replacement scheme of rules.
Except that high temperature sterilization, comparatively effective with oxirane (EO) sterilization in the common alternative sterilization, it is mainly used in simply constructed thermo-labile medical device in the medical institutes.At present international cancer research general administration (IARC) has classified EO as first order cancerigenic factor, and is exposed under these chemicals, also may cause feeling sick, symptoms such as vomiting, skin burn or pulmonary edema; In addition, research also shows that EO can cause miscarriage and fetal abnormality, or increases gastric cancer, leukemia, blood circulation diseases mortality in said patients.Main resurrectionist is the personnel of operation EO sterilizing machine in the sterilization chamber in the hospital, and in addition, constituent parts uses sterilization back equipment person, also may be exposed in the oxirane that remains on the equipment and disengage gradually.If do not design independently vented exhaust equipment at EO sterilizing machine whereabouts, based on the settling character of EO, it may be stranded in the working space, causes many people's exposure again.For in response to the potential hazard that user is caused with oxirane, just actively seek alternate sterilization mode in the world.
Though present spendable low temperature sterilization technology, except that oxirane, ion beam irradiation sterilization (Ionizing Radiation), gas slurry method (Gas Plasma) are still arranged or use phase hydrogen peroxide (VaporPhase Hydrogen Peroxide), ozone (Ozone), glacial acetic acid (Peracetic acid) and glutaraldehyde chemicals such as (glutaraldehyde), after so considering Financial cost, Disinfection Effect, suitable type of goods, epoxyethane sterilization still is the most normal method that is used.
At the thermo-labile equipment of many complex structures such as the endoscope of costliness etc., the normal at present low temperature sterilization technology of using is mainly based on liquid reaction, for example soak endoscope a period of time, and contact and eliminating bacteria and viral purpose to reach by above-mentioned medicament circulation flushing endoscope pipeline with glacial acetic acid (Peracetic acid) or glutaraldehyde chemical substances such as (glutaraldehyde).Yet the problem that international medical profession generally faces has complicated design for expensive endoscope, so that the virus that adheres in hole, pipeline and the seam can't be removed fully and eliminate via the chemical agent flushing, even the drug-fast bacterial spore of many tools, can when adverse circumstances, enter hibernation-like state, in case adverse circumstances disappear, the antibacterial of Qing Chuing can not recover activity again and causes sufferer to infect or dead, so that what is heard is arranged when cleaning bad, aleopation, dead case; And ageing the reaching of medicaments such as glutaraldehyde all can't effectively be grasped when operating the hazardness of operator's respiratory system.
This shows that above-mentioned existing method still has many disappearances, demands urgently being improved.
Summary of the invention
The object of the present invention is to provide a kind of at contaminated material utensil, contaminated general curative equipment and the medical device that can't carry out high-temperature sterilization, as endoscope, cardiac catheter, wash the sterilization treatment that carry out disinfection such as kidney machine, to reach the processing method and the device thereof of scrubbing, sterilization, sterilization purpose.
Of the present invention time a purpose is to provide a kind of cold sterilization sterilizing methods and device thereof to can be applicable to various material utensil and the medical devices that polluted by antibacterial and virus etc.
Another object of the present invention is to provide a kind of disinfecting technical fast and effectively of alternative high-temperature sterilization method, this cold sterilization sterilizing methods and device thereof can be applicable to the medical device of various design complexity or non-refractory.
The present invention is also applicable to cleaning, scrubbing, sterilization, the germ-resistant purposes of various contaminated materials, utensil, material, fresh vegetables and fruits, food etc.
Can reach the cold sterilization sterilizing methods and the device thereof of foregoing invention purpose, mainly be with various contaminated materials, medical device, as operating scissors, cutter, folder and expensive complicated endoscope, cardiac catheter, washing contaminated medical devices such as kidney machine inserts and includes ultrasound, ultraviolet, the response system of ozone and disinfectant solution, seeing through the ultrasound concussion can be with various surfaces of medical devices, hollow pipe, bacterial spore in seam and the crack, the effective desorption of virus or pollutant is removed, and then with the powerful oxidation damage capability of ozone, bacterial spore with the desorption removal, virus or organic pollution oxidation destroy, simultaneously in conjunction with ultraviolet sterilizing power, can form light-catalyzed reaction and promote reaction efficiency, the accelerate ozone oxidation destroys to be carried out; Simultaneously, disinfectant solution also contacts with bacterial spore, virus or the pollutant of desorption at this moment and it is eliminated destruction, to reach final sterilization target.
Behind the contacted human body of the medical device of many intrusive moods, with the pollutant that adhere to patient as body fluid, blood, pathogenic bacteria, virus etc.Show according to past experience, this kind pollutant adhesion is very strong, if no suitable scrubbing mode, be difficult to pollutant are eliminated fully and completely, therefore, use the main purpose of ultrasonic wave concussion, be to see through its powerful vibratory forces (Cavitations) with various surfaces of medical devices, hollow pipe, bacterial spore in seam and the crack, the effective desorption of virus or pollutant is removed, employed ultrasonic frequency is from 1~1,000,000KHz, its intensity is enough to go out medical device with little to 0.12 micron intrapore pollutant concussion desorption, and reacts with other unit in the system.
Ozone of the present invention is by behind the ozonator with air or pure oxygen, produce high-concentrated ozone, import reaction tank bottom through induction system and air delivery device again, fully mix formation saturated Ozone Water (Ozonated water) with aqueous solution, through the pollutant of supersonic desorptive with after saturated ozone in the aqueous solution contacts, carry out oxidation immediately and destroy decomposition reaction, and the pollutant of human body are carbohydrate, after ozone decomposes, can form harmless carbon dioxide and water, reach scrubbing disinfectant effect.
Ultraviolet is the disinfection tool with powerful and cheap characteristic, antibacterial or virus can be eliminated effectively, ultraviolet wavelength of the present invention is 10~400nanometer, reactive tank forms aseptic condition under ultraviolet radiation, can prevent from that bacterial virus in the outside air from contacting with medical device to cause to infect (Recontamination) again; And ozone also can form the photochemical catalysis reaction under ultraviolet radiation, quickens the destruction decomposition rate of pollutant, helps the carrying out of sterilization reaction.
Be added with chemical agent in the aqueous solution of the present invention, via pump it be delivered in the reactive tank from the chemical agent groove, see through the bacterial virus haptoreaction with desorption, chemical agent can kill it rapidly, and reaches the purpose of sterilization.Above-mentioned chemical agent is meant that general common liquid disinfectant or biocide are all applicable as: hydrogen peroxide (HydrogenPeroxide), hydrochloric acid (Hydrochloric acid), sulphuric acid (Sulfuric acid) and Hypochlorite hypochlorous acid etc., the operation concentration range is 1~200,000ppm.
Cold sterilization sterilizing methods provided by the present invention and device thereof when comparing mutually with other prior art, have more following advantage:
1. the present invention can be at handling in the surface of contaminated medical device or even the inner micro pores of pipeline, to reach scrubbing, sterilization, germ-resistant purpose.
2. the present invention can replace the high-temperature sterilization sterilization, provides medical device can carry out scrubbing, sterilization, germ-resistant technology at normal temperatures and pressures.
3. the present invention can provide the function that quick desorption is handled, and can it can't be adhered at being attached to the intrapore organic pollution of medical device, antibacterial, virus etc., to reach the effect of cleaning scrubbing.
4. the invention provides several safety and Protection, when high density pollution thing or virus adhesion, still have the multiple different oxidative decomposition device of device, can effectively destroy elimination virus or pollutant, to reach scrubbing, sterilization, germ-resistant purpose.。
5. the invention provides an aseptic reaction compartment, the gas phase and the liquid phase that comprise reactive tank all reach aseptic condition, can avoid medical device to suffer secondary pollution when sterilization operation.
6. the material of the present invention and medical device has compatibility, can not cause the situation of instrument damage to take place.
7. the low concentration harmless medicament of antiseptic sterilization agent used in the present invention after for dilution, course of reaction is for environment and operator are all unlikely works the mischief, and also can directly discharge the problem of non-secondary pollution after the use.
Description of drawings
See also the detailed description and the accompanying drawing thereof of following relevant preferred embodiment of the present invention, can further understand technology contents of the present invention and purpose effect thereof; The accompanying drawing of relevant this embodiment is:
Fig. 1 is the structure chart of cold sterilization sterilizing methods of the present invention and device thereof;
1, reactive tank device, 11, water inlet, 12, discharge outlet, 13, air vent, 2, the supersonic generator device, 3, ozonator, 31, ozone air delivery pump, 32, escape pipe, 4, ultraviolet sterilization apparatus, 5, sterilization/sterilized pharmaceutics feeding mechanism, 6, medical device, 7, reaction medicinal liquid circulating pump, 71, drinking-water pipe, 72, outlet pipe.
The specific embodiment
See also shown in Figure 1ly, cold sterilization bactericidal unit provided by the present invention is the sterilization treatment that carries out disinfection of the polluter at various design complexity or non-refractory, and this polluter comprises medical device, and it consists predominantly of:
Reactive tank device 1, this reactive tank device 1 has water inlet 11, discharge outlet 12 and air vent 13, this water inlet 11 and outlet 12 mainly are that water supply solution 14 enters and discharges, and air vent 13 its mainly be for the discharging of the gas in the reactive tank 1; Medical device 6 is inserted in the reactive tank device 1, with the sterilization treatment reaction that carries out disinfection;
Supersonic generator device 2 can provide 1~1,000, the ultrasound wave of 000KHz frequency, can be installed on reactive tank 1 outside or insert reactive tank device 1 inside in the mode of reacting rod, aqueous solution 14 its liquid levels of inserting in the groove also surpass medical device, and hyperacoustic vibratory forces can go out medical device with the pollutant desorption in the micro gap completely;
Ozonator 3, this ozonator 3 has ozone air delivery pump 31, this ozone air delivery pump 31 can enter air or pure oxygen guiding in the ozone generating-device 3, so that the ozone with powerful oxidability to be provided by ozonator 3, and this ozone is delivered in the aqueous solution in the reactive tank device 1, with the sterilization processing that carries out disinfection at the polluter on the medical device 6 that immerses in the solution via escape pipe 32;
Ultraviolet sterilization apparatus 4, this ultraviolet sterilization apparatus 4 be based on Burdick lamp equipment, and its wavelength also can install photocatalyst TiO additional from 100 to 400nm 2Device when ultraviolet and ozone contact reaction, can form light-catalyzed reaction, gaseous state and liquid oxidatively reaction rate in the reactive tank device 1 are significantly promoted, but the pollutant or the pathogenic bacteria of destroying remnants is decomposed in fast reaction;
Sterilization/sterilized pharmaceutics feeding mechanism 5, it comprises sterilization/sterilized pharmaceutics groove and delivery pump, medicament can be imported in the reactive tank device 1, and be 1 to 200 according to specifying the drug concentration mixed diluting, the concentration of 000ppm, can be effectively and the pollutant of desorption or pathogenic bacteria haptoreaction, reach the purpose of disinfection;
Reaction medicinal liquid circulating pump 7, this reaction medicinal liquid circulating pump 7 includes drinking-water pipe 71 and outlet pipe 72, this drinking-water pipe 71 joins with the bottom surface of reactive tank device 1, outlet pipe 72 then joins with medical device 6, seeing through reaction medicinal liquid circulating pump 7 can extract the liquid medicine in the reactive tank device 1 through drinking-water pipe 71, and inject medical devices 6 through drain pipe 72, with the sterilization that carries out disinfection of the inside at medical device 6;
The present invention by supersonic generator device 2 will be attached in various medical devices 6 surfaces, hollow pipe, hole and the crack bacterial spore, virus or pollutant fast effectively desorption remove, desorption power is permeable to little hole to 0.12 micron; One or more powerful chemical medicament and the sterilization/bactericidal agent of Food and Drug Administration (FDA) approval such as sodium hypochlorite (Hypochlorite), hydrogen peroxide (H are housed in the sterilization/sterilized pharmaceutics feeding mechanism 5 simultaneously, 2O 2), sulphuric acid (Sulfuric acid) etc., and by contacting with medical device after 7 dilutions of reaction medicinal liquid circulating pump, it can effectively be eliminated by the antibacterial of ultrasonic wave concussion desorption and virus, simultaneously be dissolved in aqueous solution in powerful oxidant, ozone contact, can be with the organic pollution oxidation Decomposition, with the bactericidal reaction that carries out disinfection, and can pass through ultraviolet, the reaction of photocatalyst and ozone with the small portion of residual unreacted completely pollutant under light-catalyzed reaction, decompose bactericidal reaction fast, be present in the surface or even the inner micro pores of pipeline of medical device to guarantee not have amounts of residual contamination do or virus.
At last, oversaturated ozone gas will be followed the top that rises to reactive tank device 1, and form sterilized space with ultraviolet, guaranteeing in the sterilization process, and not reason ambient atmos and water quality transmission and cause the medical device secondary pollution.

Claims (10)

1. cold sterilization sterilizing methods, it is characterized in that: mainly be that contaminated material or utensil or medical device are inserted in the reactive tank device of sterilization, with the supersonic generator device will be attached in various complicated surfaces of medical devices, hollow pipe, hole and the crack bacterial spore, virus or pollutant fast effectively desorption remove; Simultaneously, the pollutant that desorption is removed contact with the powerful oxidant, ozone in being dissolved in aqueous solution, pollutant oxidation can be decomposed, with the bactericidal reaction that carries out disinfection, and the reaction that can pass through ultraviolet, photocatalyst and ozone with the small portion of residual unreacted completely pollutant under light-catalyzed reaction, decompose bactericidal reaction fast, guarantee not have amounts of residual contamination do or virus and be present in the surface or even the inner micro pores of pipeline of medical device.
2. cold sterilization sterilizing methods, it is characterized in that: mainly be that contaminated material or utensil or medical device are inserted in the reactive tank device of sterilization, with the supersonic generator device will be attached in various complicated surfaces of medical devices, hollow pipe, hole and the crack bacterial spore, virus or pollutant fast effectively desorption remove; Simultaneously, the pollutant that desorption is removed contact with the powerful oxidant, ozone in being dissolved in aqueous solution, pollutant oxidation can be decomposed, with the bactericidal reaction that carries out disinfection, and the reaction that can pass through ultraviolet, photocatalyst and ozone with pollutant under light-catalyzed reaction, decompose bactericidal reaction fast, guarantee not have amounts of residual contamination do or virus and be present in the surface or even the inner micro pores of pipeline of medical device; Simultaneously, contact with medical device, it can effectively be eliminated by the antibacterial of ultrasonic wave concussion desorption and virus by the powerful chemical medicament of reaction medicinal liquid circulating pump with one or more.
3. cold sterilization sterilizing methods according to claim 1 and 2, it is characterized in that: described supersaturation ozone gas will be followed the top that rises to the reactive tank device, and form sterilized space with ultraviolet, guaranteeing in the sterilization process, not reason ambient atmos and water quality transmission and cause the secondary pollution of medical device.
4. cold sterilization bactericidal unit, it is characterized in that: it comprises:
Contaminated medical device can be inserted the reactive tank device of the sterilization treatment that carries out disinfection;
Effectively the intrapore nano-bacteria of the contaminated medical device of desorption with virus the supersonic generator device;
Ozone can be delivered to the ozonator in the aqueous solution in the reactive tank device, with the sterilization processing that carries out disinfection of the polluter at the medical device in the liquid;
When ultraviolet sterilization apparatus, itself and ozone contact reaction, can form light-catalyzed reaction, gaseous state and liquid oxidatively reaction rate in the reactive tank device are significantly promoted, but fast reaction is decomposed and destroyed remaining pollutant or pathogenic bacteria.
5. cold sterilization bactericidal unit, it is characterized in that: it comprises:
Contaminated medical device can be inserted the reactive tank device of the sterilization treatment that carries out disinfection;
Effectively the intrapore nano-bacteria of the contaminated medical device of desorption with virus the supersonic generator device;
Ozone can be delivered to the ozonator in the aqueous solution of reactive tank device, with the sterilization processing that carries out disinfection of the polluter at the medical device in the liquid;
When ultraviolet sterilization apparatus, itself and ozone contact reaction, can form light-catalyzed reaction, gaseous state and liquid oxidatively reaction rate in the reactive tank device are significantly promoted, but fast reaction is decomposed and destroyed remaining pollutant or pathogenic bacteria;
Sterilization/sterilized pharmaceutics feeding mechanism, be filled with powerful sterilization/bactericidal agent in it, and, can dilute into the reactive tank device interior so that pollutant are carried out reaction treatment in wherein being provided with delivery pump, guarantee that pollutant contact fully with sterilization/bactericidal agent and strong oxidizer, and then its oxidation is destroyed;
Reaction medicinal liquid circulating pump, it can inject medical device with the liquid medicine in the reactive tank device, with the sterilization that carries out disinfection of the inside at medical device.
6. according to claim 4 or 5 described cold sterilization bactericidal units, it is characterized in that: described reactive tank device has water inlet, discharge outlet that main water supply solution enters and discharge and the air vent that discharges for interior the gas of reactive tank.
7. according to claim 4 or 5 described cold sterilization bactericidal units, it is characterized in that: described supersonic generator device can provide from 1~1,000, the ultrasound wave of 000KHz frequency, can be installed on the reactive tank outside or insert reactive tank device inside in the mode of reacting rod, its liquid level of the aqueous solution of inserting in the groove also surpasses medical device, so that the pollutant desorption in the micro gap is gone out medical device.
8. according to claim 4 or 5 described cold sterilization bactericidal units, it is characterized in that: described ozonator has the ozone air delivery pump, this ozone air delivery pump can enter air or pure oxygen guiding in the ozonator, so that the ozone of the powerful oxidability of tool to be provided by ozonator, and this ozone is delivered in the aqueous solution in the reactive tank device via escape pipe.
9. according to claim 4 or 5 described cold sterilization bactericidal units, it is characterized in that: described ultraviolet sterilization apparatus is a Burdick lamp equipment, and its wavelength maybe can install photocatalyst TiO additional from 100 to 400nm 2Device.
10. cold sterilization bactericidal unit according to claim 5, it is characterized in that: described reaction medicinal liquid circulating pump includes drinking-water pipe and outlet pipe, the bottom surface of this drinking-water pipe and reactive tank device joins, outlet pipe then joins with medical device, liquid medicine in the reactive tank device can be extracted through drinking-water pipe by reaction medicinal liquid circulating pump, and inject medical device through drain pipe, with the sterilization that carries out disinfection of the inside at medical device.
CN 200510119836 2005-11-08 2005-11-08 Hypothermia sterilization method and apparatus thereof Pending CN1961964A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101914847A (en) * 2010-07-29 2010-12-15 湖北康源药业有限公司 Medicinal lining cloth and processing method thereof
CN106178024A (en) * 2016-07-06 2016-12-07 安徽智博新材料科技有限公司 A kind of long-acting disinfection method of medical appliance
CN106974165A (en) * 2017-04-28 2017-07-25 山东广达源照明电器有限公司 A kind of device and method of fruits and vegetables sterilizing and chemical agent of degrading
CN108324969A (en) * 2018-05-03 2018-07-27 王晓黎 A kind of indoor Quick disinfecting device of medical condition prevention
CN109237653A (en) * 2018-07-31 2019-01-18 遵义医学院 Air purifier
CN109420187A (en) * 2017-08-30 2019-03-05 邢介云 Medical ethylene oxide sterilizing device
CN111036612A (en) * 2019-11-13 2020-04-21 丁力行 Invasive medical equipment cleaning, disinfecting and sterilizing device

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101914847A (en) * 2010-07-29 2010-12-15 湖北康源药业有限公司 Medicinal lining cloth and processing method thereof
CN106178024A (en) * 2016-07-06 2016-12-07 安徽智博新材料科技有限公司 A kind of long-acting disinfection method of medical appliance
CN106974165A (en) * 2017-04-28 2017-07-25 山东广达源照明电器有限公司 A kind of device and method of fruits and vegetables sterilizing and chemical agent of degrading
CN109420187A (en) * 2017-08-30 2019-03-05 邢介云 Medical ethylene oxide sterilizing device
CN109420187B (en) * 2017-08-30 2021-03-02 贾兰玲 Medical ethylene oxide sterilization device
CN108324969A (en) * 2018-05-03 2018-07-27 王晓黎 A kind of indoor Quick disinfecting device of medical condition prevention
CN109237653A (en) * 2018-07-31 2019-01-18 遵义医学院 Air purifier
CN111036612A (en) * 2019-11-13 2020-04-21 丁力行 Invasive medical equipment cleaning, disinfecting and sterilizing device

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