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Priority claimed from US10/646,798external-prioritypatent/US20040048315A1/en
Application filed by Pharmacia CorpfiledCriticalPharmacia Corp
Publication of TW200502248ApublicationCriticalpatent/TW200502248A/en
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Publication of TWI318629BpublicationCriticalpatent/TWI318629B/en
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Abstract
The present invention is directed generally to recombinant methods for making a desired pegylated protein and pooling of same. These method(s) yield a polypeptide product containing reduced levels of aggregate thereof pooled to provide the desired pegylated isoforms thereof.
TW92126051A2002-09-202003-09-22Process for decreasing aggregate levels of pegylated protein
TWI318629B
(en)
NEW AMINOPEPTIDASE FROM BACILLUS licheniformis, the gene encoding the aminopeptidase, the expression vector containing the gene, the transformant and the method for producing the same