NZ332903A - Angiostatin fragments and aggregate angiostatin and methods for inhibiting endothelial cell proliferation - Google Patents

Angiostatin fragments and aggregate angiostatin and methods for inhibiting endothelial cell proliferation

Info

Publication number
NZ332903A
NZ332903A NZ332903A NZ33290396A NZ332903A NZ 332903 A NZ332903 A NZ 332903A NZ 332903 A NZ332903 A NZ 332903A NZ 33290396 A NZ33290396 A NZ 33290396A NZ 332903 A NZ332903 A NZ 332903A
Authority
NZ
New Zealand
Prior art keywords
angiostatin
cell proliferation
endothelial cell
methods
inhibiting endothelial
Prior art date
Application number
NZ332903A
Inventor
M Judah Folkman
Michael S O'reilly
Yihai Cao
Jie Lin
Original Assignee
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/429,743 external-priority patent/US5885795A/en
Priority claimed from US08/605,598 external-priority patent/US5861372A/en
Priority claimed from US08/612,788 external-priority patent/US5837682A/en
Application filed by Childrens Medical Center filed Critical Childrens Medical Center
Priority claimed from NZ307044A external-priority patent/NZ307044A/en
Publication of NZ332903A publication Critical patent/NZ332903A/en

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  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

This composition, which is useful for inhibiting endothelial cell proliferation, comprises substantially purified aggregate angiostatin protein which is a recombinantly produced protein and contains a kringle 1-4 region of a plasminogen molecule.
NZ332903A 1995-04-26 1996-04-26 Angiostatin fragments and aggregate angiostatin and methods for inhibiting endothelial cell proliferation NZ332903A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/429,743 US5885795A (en) 1994-04-26 1995-04-26 Methods of expressing angiostatic protein
US08/605,598 US5861372A (en) 1996-02-22 1996-02-22 Aggregate angiostatin and method of use
US08/612,788 US5837682A (en) 1996-03-08 1996-03-08 Angiostatin fragments and method of use
NZ307044A NZ307044A (en) 1995-04-26 1996-04-26 Angiostatin fragments with antiangiogenic activity

Publications (1)

Publication Number Publication Date
NZ332903A true NZ332903A (en) 2000-04-28

Family

ID=27484361

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ332903A NZ332903A (en) 1995-04-26 1996-04-26 Angiostatin fragments and aggregate angiostatin and methods for inhibiting endothelial cell proliferation

Country Status (1)

Country Link
NZ (1) NZ332903A (en)

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