TW200416047A - The novel preparation of two-layer burn wound dressings - Google Patents

Abstract

Preparation of radiation-induced grafted acrylic acid/N-isopropylacrylamide (NIPAAm) temporary wound dressing materials is disclosed in this present. The nonwoven fabric of polypropylene (PP) can be modified by Co60 γ-ray or UV simultaneous irradiation with acrylic acid or N-isopropylacrylamide. The two methods are used in the steady, one is γ-ray irradiation and the other is UV light irradiation. As the enhancement of water vapour transmission rates, wettability and antibacterial activity of the modified nonwoven fabric of polypropylene, the modified nonwoven fabric of polypropylene can be used for the wound dressing.

Description

200416047 V. Description of the invention (1) 1. [Technical field to which the invention belongs]: This invention + Ming is related to the manufacturing method of burns and scald dressing, especially a kind of non-woven f borrowing gamma rays or UV light to make A method for graft polymerization of acrylic acid and isopropylpropyl siamine on a non-woven fabric to form a burn and scald dressing. 2. [Previous technology] The skin is the largest organ of the human body. For example, the epidermis of a 65kg body has about 2m ^ 2 1 ί iH protects the body, regulates body temperature, secretion and perspiration, feels and stores a knife. General burns can be divided into three levels: Grade 1 (degree) burns, epidermal burns 2, and (degrees) wounds, superficial dermal welding, grade 3 (degrees), wounds, subcutaneous burns, or severe dermal burns, which are above 30%. 2 degrees or i 〇% is equal to, = weaving necrosis) 3 degrees above the injury is the most serious, life-threatening <3 degree burns, if 70% of the treatment is inadequate skin care, respectfully special Medical. The main role of dressing in treatment is to prevent moisture in the body: it must first-temporarily protect the environment &amp; use gauze to cover wounds such as epidermal cells to enter and disperse ^ and prevent infection, and the traditional burning expenses can be repeated. η. μ # β ^ ^ Dressings are most commonly gauze% • Also when in the mouth, gauze will be completely absorbed by the wound and smeared out: The body usually contains some of the wound healing fluid (exudate), and the mouth recovery is delayed. When removing the gauze material, the gauze material will cause injuries 0 k = one or two injuries, and fine debris will remain in the wound ^ will pull the wound and penetrate the gauze to reach the wound, and then cause injuries! : 丨. In addition, bacterial wear can have a great effect on wound healing / infection &amp; infection. Oxygen content &amp; bitter covered wounds

200416047 V. Description of the invention (2) If too much body fluid is produced, oxygen may not easily enter the second wound for healing after penetrating the dressing, and it may be difficult for the dressing to leak body fluid. Therefore, a material used as a scald dressing should first consider its ability to absorb body fluids (hydrophilicity), gas permeability (oxygen gas, water gas, etc.), and antibacterial properties. &amp; In addition, the graft polymerization method by light irradiation has been used in the plastics industry. =: Xie Xiangjun and others have published that grafting of NI'PAA tender high-son medical films with UV light to improve wet slippage. And it is expected to be used in medical catheters. ΤLokhande et al. Published the use of τ-light irradiation to graft acrylic eyes, (acrylic nitrile) on plastic diaphragms. But so far, no one has used "non-woven fabric as the base material, and used gamma rays to radiate and shine with Uy." Graft acrylic acid and isopropylacrylamide onto the surface of the non-woven fabric and burned them. Dressing. ^ Non-woven fabric is very suitable for burns due to its porosity, large surface area, high porosity, dust-free, easy to process, and surface modification function. ^ Materials. Acrylic acid has good carboxylic acid groups Hydrophilic, can absorb a lot of water 'and has good biocompatibility. N-isopropylacrylamide (NIPAAm) has temperature sensitivity, and its lower critical solution temperature (lower critical solution temperature, LCST) is about 32. (:, when the temperature is below LCST, its water absorption and swelling is a hydrophilic substance, and its mechanical properties are poor; when the temperature is higher than LCST, its condensation and contraction become a hydrophobic substance, its mechanical properties are relatively Good, so when it is covered on human skin, because the body temperature is higher than LCST, NIPAAm is hydrophobic at this time.

200416047 NIPAAm will avoid the polymer reaction caused by radiography] Light irradiation and other common research and development of the purpose of the use of gamma radiation cloth, C, to form a catalogue of good energy requirements after the use of equipment, According to the request of the non-woven shooting method, there is a high use of non-woven and breathable, and the burning cloth of the present invention is used as a base material, and the aqueous and antibacterial solution of the solution is used as a breathable porous UV light irradiation method to modify and The antibacterial property is hydrophilic as a kind of burn and scald irradiated with gamma automatically absorbing water, thereby making it easy to peel and hurt wounds. It is more uniform and most convenient and clean, because of the modification of the material. The characteristics and profit experiments of branch polymerization and non-woven fabrics have completed the present invention. The invention provides a manufacturing line for burns and scald dressing. Nanen radiation and UV light irradiation are used to graft the pre-acrylic acid monomer and isopropylacrylamide graft polymer to have good air permeability, hydrophilicity and antibacterial properties. Explanation (3) It is immersed in cold water and peeled off, so it can be used in light. [In view of the above point in the invention, the inventor therefore, this method is mainly used to woven non-woven fabric first. Burns and dressings. In order to achieve a highly breathable porous gamma ray cloth, a necessary method to impart a scald dressing is the necessity of grafting and polymerization of melamine and temperature-sensitive wound dressings treated with a liquid soak solution. 'M ~ Θ ^ promote The wound dressing on non-woven fabrics that have been treated with solution is mainly made by using a solution soak treatment, and then the acrylic polymer is grafted on the non-woven fabric, so that the product can meet the burns dressing. The non-woven fabric of the present invention is made by dissolving the base material, and the non-woven fabric made of acrylic and isopropyl propylene has hydrophilicity, etc., and it also satisfies the use of burn-in dressing. The preparation method of the material is based on receiving or polymerizing propionate 200416047 through radiation or UV light. (5) Description of the invention (4) or acrylic acid and isopropylacrylamide are polymerized on the surface of the non-woven fabric to form a breathable, hydrophilic, antibacterial Dressing for sexual burns. The scald dressing of the present invention can be made in two ways according to the irradiation light used. The first way is to use polypropylene (PP) non-woven fabric as the base material. First prepare several pieces of this non-woven fabric and soak them in acrylic solutions prepared at different concentrations (10% ~ 40%, ethanol as solvent), and soak them. · 5 ~ 1 day, then remove each piece of non-woven fabric into each sealed bag, and add an appropriate amount of acrylic acid solution of different concentration, for example, add 5 ~ 10 m 1 to the bag of 8 c mx 8 cm substrate, and then Simultaneous irradiation with gamma ray irradiation, the irradiation time is 0 ~ 10 hours, the irradiation dose rate is 0.5 ~ lOkGy / hr, the total irradiation dose is about 5 ~ 6 0 kGy, and the irradiation is washed and washed with deionized water. Non-woven fabric, put it in a dark place and let it dry naturally, this product is completed. The second approach is to immerse multiple pieces of polypropylene (PP) non-woven fabric in mixed solutions of acrylic acid and isopropylacrylamide (NIPA Am) prepared at different mixing ratios. The acrylic acid solution [10% (V / V), Soluble in ethanol] The ratio of NIPAAm solution (0 · 148g NIP A Am / 1ml ethanol) is set at 1/0, 3/1, 1/1, 1/3, 0/1 (V / V)), soak After 1 to 2 days, take out the non-woven fabric and place it on a Teflon plate, and then drop in an appropriate amount, for example, add 5 to 1 0 m 1 of a mixed solution of acrylic acid and isopropylacrylamide to the non-woven fabric. The solution contains less than 5% by weight of benzo ine thy 1 e ther (BEE) as an initiator, and then the non-woven fabric is irradiated with UV light for an irradiation time of 10 to 60 minutes, and the non-woven fabric is taken out after the irradiation. The surface layer forms a layer of gelatinous substance, which completes the product. The above mixed solution of acrylic acid and isopropylacrylamide can also be used.

Page 10 200416047 V. Description of the invention (5) Replacement of monomer solution with similar properties. 4. [Embodiment] '[Example 1] Acrylic acid is irradiated onto the non-woven fabric by gamma-ray high-energy radiation method:

&amp; s two Λ woven fabric as the base material (pp, 8cmx 8cm, Figure 2 · shows this base material = wide I piece), first immerse the non-woven fabric in 40% acrylic acid solution (ethanol is / Gu Qi I), Alpha soak for 1 day, then put the non-woven fabric in a sealed bag, and add 40% acrylic solution 100m 1 into the bag, and then irradiate with gamma rays for simultaneous irradiation, the irradiation time is 0 ~ 丨 0 hours, The irradiation metering rate is 0.5 ~ 丨 〇Gy / hr, and the total irradiation dose is about 5 ~ 60kGy. After the irradiation, it is washed with deionized water and placed in a dark place to allow it to dry naturally. The picture shows its SEM photo 'showing grafted tissue. [Example 2] Acrylic solution was grafted onto a non-woven fabric by UV light irradiation: The non-woven fabric was used as a base material (pp, 8Cfflx gcm, and the first and second pictures are SεM photos), and the non-woven fabric was immersed in an acrylic solution (1〇 % (ν / ν), soluble in ethanol), soak for 2 days, then take out the non-woven fabric and place it on a Teflon plate, and then drip 10 m 1 acrylic solution onto the non-woven fabric, the solution contains less than 5 weight. 〇 Benzoin ethyl ether (BEE) as the light initiator, and then irradiate it [JV light after removal,

The irradiation time is 10 to 100 minutes. After the irradiation, a gel layer is formed, and the product is completed. The fifth to sixth pictures are SEM photos. [Example 3] Acrylic acid and isopropylacrylamide solution were grafted onto a non-woven fabric by UV light irradiation:

Page 11 200416047 V. Description of the invention (6) Non-woven cloth is used as the basic word (pp, 8cmx 8cm, the first and second pictures are SEM photos), and the non-woven cloth is immersed in a mixed solution of acrylic acid and isopropylacrylamide (NIPAAm). In the acrylic acid solution [10% (V / V), soluble in ethanol] to isopropylacrylamide solution (0.148g NIPAAm / 1ml ethanol), the mixing ratio is 1 /; 1 (V / V), soak After 2 days, the non-woven fabric was taken out and placed on a Teflon plate, and then 10 m of a mixed solution of 1 acrylic acid and isopropyl propylamine was dropped on the non-woven fabric, and the solution contained less than 5% by weight of benzoin Diethyl ether (bee) When the initiator is irradiated with UV light, it is taken out. The irradiation time is 10 to 100 minutes. After irradiation, it forms a gelatinous layer to complete the product. The seventh to eighth pictures are SE Ｍ 照 ^ ^ ......

[Example 4] Isopropylacrylamide solution was irradiated with a UV light irradiation method onto a nonwoven fabric using a nonwoven fabric as a base material (pp, 8 cm x 8 cm, Figs. 1 to 2 · is a SEM photograph thereof), and the nonwoven fabric was immersed in an isopropyl amine solution. Propylacrylamide solution (0.148g NIPAAm / lml ethanol), soak for 2 days, then take out the non-woven cloth and place it on a Teflon dish, and then add 1 Om 1 acrylic acid and isopropylacrylamide mixed solution in On the non-woven fabric, the solution contains less than 5% by weight of benzoin ethyl ether as a starter, and then it is irradiated with UV light and taken out. The irradiation time is 10 to 100 minutes. After irradiation, it forms a gelatinous layer, that is, Finish this product, the ninth ~ "picture is its SEM photo. It can be seen from the above examples that the surface of the non-woven fabric treated by the method of the present invention shows graft polymerization (Figures 3 to 10). In addition, the effect of the gamma-ray high-energy radiation method on the graft polymerization of acrylic acid can be seen in Figures Η-- ~ 12, and Figure Η can be seen in a fixed irradiation ring

Page 12 V. Description of the invention (7) ____ _ — ^ Under the environment, the value of irradiation is small, especially after the capture, the acrylic acid grafting rate will gradually reach a balance. After the twelfth figure B, the selection of the irradiation time is about 4 hours, which is the optimum radiation dose rate. The graph of the irradiation dose rate versus the acrylic acid grafting rate shows that the selection rate is the same: the higher the branching rate is. From the eleventh and twelfth pictures, the irradiation range is 0 ~ 10 hours, and the dose rate is 0.5 ~ 10kGy / hr. After the irradiation method, the irradiation dose is about 5 ~ 60kGP via gamma-ray high-energy radiation. It affects the properties, the amount of acrylic acid irradiated on the woven fabric will affect the hydrophilic acrylic on the hydrophilic fabric. As shown in Table 1 ~ 2, it can be seen from Table 2 · that the non-woven rate and the diffusion rate increase. , Its relative water absorption time decreases, the maximum water absorption ray high-energy radiation increases, showing that its hydrophilicity increases. In addition, after the gamma bacterium effect b is treated in the same way, the acrylic nonwoven fabrics that have better killing will promote who will be promoted. As shown, the table shows that the nonwovens themselves will not sterilize and grow. When the non-woven fabric contains acrylic acid, it has an S effect, which can greatly reduce the number of bacteria. Table * 1 Jingyou Qiu I 6 丄 i 璧 十 and water time (Graft ratio vs. relative wicking time) rate (wt%) relative water absorption time 0.00.000 1.000 〇. 440 0. 900 1.560 0.880 6.020 0. 870 10.280 -------- 0.860 phase, W code ray high-energy radiation method, the grafting rate of the product and A 〇a A1 〇b A20c A3〇a A40e I ^ ϋ Page 13 200416047 V. Description of the invention ( 8) a. Non-woven fabric, \ b · Acrylic non-woven fabric prepared by irradiating cobalt 60 with a 10% acrylic acid solution c. Acrylic non-woven fabric prepared by irradiating cobalt 60 with a 20% acrylic acid solution d Acrylic-containing non-woven fabric prepared by irradiation of 0% acrylic acid solution with cobalt sixty e · Acrylic-containing non-woven fabric prepared by irradiation of 40% acrylic acid solution with cobalt 60

f. Relative water absorption time is measured at 25 ° C. Table 2 · Maximum water absorption and diffusion coefficient of products made by gamma-ray high-energy radiation method (Maximum water content on various samples)

Sample 1 Maximum water absorption (wt%) Diffusion coefficient (x 107, cm2 / sec) AO 350.000 0.760 A10 385.000 3.060 A20 415. 000 4. 520 A30 430.000 3. 100 A40 525-000 7. 930

Page 14 200416047

V. Explanation of the invention (9) Table 3 · Antibacterial assessment varius US samples of products made by gamma radiation and radiation method (Pseudomonas aeruginosa Staphylococcus aureus CFU / ml) X 1 0-7 (CFU / ml) X 10- 7 Blank 1250 • 0 0 0 soil 450. 000 500.00〇 soil 30 0. 000 A0 3 3 6 0 • 0 0 0 soil 340 0 .000 283 · 000 Taxi 23 2. 000 A40 1. 2 3 0 taxi 0 .970 0 · 252 soil 0 · 247 A30 6 • 0 70 soil 4. 220 1. 950 soil 0. 250 A20 14 • 70 0 soil 11. 500 3 · 970 Soil 1. 670 A10 20 • 0 0 0 Soil 15. 800 4.000 Soil 3. 000 CFU = Co1ony Forming Un its Treatment by UV light irradiation treatment: Afterwards, acrylic acid and isopropyl on the non-woven fabric The amount of propylammonium: it will affect its hydrophilicity and breathability, as shown in Tables 4 and 6. From Table 4, it can be seen that as the content of acrylic acid decreases, the content of isopropylacrylamide increases. , Its relative water absorption time increases, its WVTR (water vapour transmission rates), water permeability, and air permeability are all Decline, since more absorbent than isopropyl acrylate, propylene Amides, so when the amount of acrylic acid, reducing its hydrophilicity and moisture permeability. The non-woven fabric treated by the UV light irradiation method does not have much influence on the properties of the material itself, as shown in Table 5. It is known from Table 5. ^; the stress of samples with acrylic acid and isopropylacrylamide It is about the same as the non-woven fabric. It shows that the modification does not affect the tensile strength of the material itself, but the strain is smaller than that of the non-woven fabric.

Page 15 200416047 V. Description of the invention (10) Table 4 · Graft ratio vs. relative wicking time of products made by UV light # method Sample graft ratio (wt%) Relative water absorption time A0 AN10a AN31 b AN1 1 c AN13d AN01 e 0.000 680.380 863.160 921.770 1084.810 1180. 130 1 · 0 0 0 ± 0 · 0 9 6 0 · 0 1 7 ± 0 · 0 0 9 0 · 11 4 ± 0 · 0 3 5 〇. 3 8 4 ± 0.055 〇 · 4 5 6 ± 0 · 0 3 7 〇 · 4 8 9 ± 0 · 0 2 7

a. b · A non-woven fabric prepared by mixing a mixed solution of acrylic acid / isopropylacrylamide at a ratio of 1 / 〇 under UV light c. d. e.

Non-woven fabrics made with acrylic / isopropylacrylic acid and UV light irradiated with acrylic / isopropylacrylamide. Mix ratios of acrylic I / isopropylpropylene made with non-woven fabrics made with UV light Non-woven fabrics prepared by UV light irradiation with acryl / isopropylacrylamide. The water absorption time of non-woven fabrics prepared by UV light irradiation is 3/1 measured at 25 ° C. Mixed solution 1/1 mixed solution 1/3 mixed solution 0/1 mixed solution

Page 16 200416047 V. Description of the invention (π) Table 5 · Stress and Strain (Stg and Strain) of the product made by UV light and radiation method Sample stress (Kg / mm2) Strain (%) AO 0 · 230 Soil 0.100 19 · 370 Soil 6.260 AN10 0 · 190 Soil 0.060 3. 710 + 0.750 AN31 0 · 200 Soil 0.050 6 · 880 Soil 1.430 AN11 0 · 210 Soil 0.080 6. 040 ± 1.910 AN13 0 · 230 Soil 0.080 12 · 860 Soil 3.460 AN01 0 · 210 soil 0.060 11 · 350 soil 3.290 Table 6 · Water vapor transmission test (WVTR, Permeance, and Permeability of samples) of products made by UV light irradiation method (VVTR) (WVTR) ( g / ra2 / day) Permeance (Kg / m2 / Pa / s) x 108 Permeability (Kg / ra / Pa / s) x 1012 A0 12869. 000 4.750 4. 040 AN10 18915.800 6 . 980 9.770 AN31 10200. 500 3. 760 8. 660 AN11 3238.300 1.190 4. 000 AN13 2521.000 0.930 1. 860 AN01 3174.300 1.170 2.580

200416047 V. Description of the invention (12) WVTR = water vapor transmission rates. In addition, after being treated by UV light irradiation, the non-woven fabric containing isopropylacrylamide has temperature sensitivity, as shown in Table 7 · From Table 7 · It can be seen that the non-woven fabric containing isopropylacrylamide at 15 ° C and 25 ° C has a smaller water absorption time than that at 41 ° C and 5 3 ° C, showing that it is at 1 ° C, 2 5 Good hydrophilicity at ° C, at 4 TC, 53. (: Hydrophilicity is poor, and the change in hydrophilicity can prove that the non-woven fabric containing isopropylacrylamide has temperature sensitivity. Finally, after treatment by UV light irradiation, the non-woven fabric containing acrylic acid and isopropylacrylamide It has better bactericidal effect, as shown in Table 8. · From Table 8 · It can be seen that the non-woven fabric itself does not sterilize but promotes the growth of bacteria. When the non-woven fabric contains acrylic acid and isopropylacrylamide, it has a bactericidal effect. Significantly reduce the number of bacteria. Table 7. Temperature effect test (Temperature effect in relative wicking time of various samples) of products made by UV light irradiation (Ct) 15 25 41 53 AO LOOOiO.OOl 1.000 ± 0.096 1.000 ± 0.004 1.000 ± 0.009 AN10 0.036db0.004 0.017 ± 0 · 009 0.111 ± 0.014 0.151 ± 0 · 035 AN31 0.039 ± 0.006 0.114 ± 0.035 0.160 ± 0.012 0.269 ± 0.055 AN11 0.042 ± 0.005 0.384 ± 0.055 0.637 ± 0.018 0.529 ± 0.009 AN13 0.043db0.005 0.456 ± 0.037 0.651db〇.〇13 0.645 ± 0.019 AN01 0.049 ± 0.002 \ 0.489 ± 0.027 0.659 ± 0.0146 0.666 ± 0.028

Page 18 200416047 V. Description of the invention (13) Table 8. Antibacterial assessment of various samples made by UV light irradiation method (Antibacterial assessment of various samples) Sample Adenophyllum aeruginosa (CFU / ml) X 10-7 Staphylococcus aureus (CFU / ml) X 1〇-7 blank 46800.00 0+ 33300.000 3 0 0 0 · 0 0 0 ± 2 0 0. 0 0 0 A0 88100. 00 0 ± 69100.000 2 5 6 0 0 · 0 0 0 ± 1 5 5 0 0 · 0 0 0 AN10 1 · 870 ± 1.300 0 · 0 1 7 ± 0 · 0 0 9 AN31 3, 9 0 0 ± 1 · 6 1 0 0 · 0 2 0 ± 0 · 0 1 0 AN11 14.80 0 ± 11.900 0. 10 6 ± 0.0 74 AN13 2 1 4 · 0 0 0 ± 2 1 2 · 0 〇〇76.00 0 ± 33.900 AN01 3 0 3 · 0 〇〇 Soil 1 6 7 · 0 〇〇1 7 1. 0 0 0 ± 4 9.5 0 0 According to the above examples and diagrams, the present invention has the following advantages: 1. The present invention uses a cheap non-woven fabric as the substrate, and then uses acrylic acid and isopropylpropane Amine is modified, so its manufacturing cost is not high and it has economic benefits. 2. The present invention is to irradiate the non-woven fabric with high-energy gamma-ray light irradiation and UV light irradiation, and graft polymerize the acrylic monomer and isopropylacrylamide onto the non-woven fabric. The manufacturing process is simple, clean and pollution-free. 3. The product produced by the method of the present invention has good hydrophilicity (Tables 2, 4), can absorb a large amount of body fluids of the wound, and keeps the wound in an appropriate moist state, so that the wound has a better healing effect, Also this product has

Page 19 200416047 V. Description of the invention (14) It has a bactericidal effect and reduces the chance of bacterial infection of the wound (Table 3, 8 ·). 4 · The product produced by the method of the present invention has better peelability (Table 7 ·) and antibacterial properties than traditional gauze, does not cause secondary damage to the wound, and has great medical application value. 5. The WVTR value of commercial burns and scald dressings is between 30 ~ 100 0 0 (g / m2 / day), and the WVTR value of products manufactured by this product method is also in this range (Table 6). Therefore, the breathability of this product is not inferior to some commercialized burns and dressings.

200416047 The diagram briefly illustrates the product A40 produced by the electron microscope of φ. The first image is a photo of a non-woven, untreated (A〇 (SEM). F The second image is a non-woven before untreated (A〇 ( (SEM) photo. M The third image is an electron microscope (SEM) image of the surface of the high-energy radiation with gamma rays. / The fourth image is an electron microscope (SEM) image of the cross section of the high-energy light-emitting gamma rays. The fifth image of the product A40 produced by the UV light irradiation method (SEM) photograph. 4 The product of the AN 10 surface of the fourth product by the UV light irradiation method 丨 Yan Zuoshanzi microscope (SEM) photo. The seventh image of the cross-section of the product AN10 was irradiated with UV light by a microscope (SEM). The eighth image of the surface of the product AN 1 1 was produced by UV light &amp; a sub-microscope ( SEM) photo. The ninth image of the cross section of the product AN 1 1 produced by the UV light irradiation microscope (SEM) photo. The tenth image of the surface of the product AN01 produced by the UV light irradiation microscope (SEM) photo . Electronic section of the product AN01 A picture with the gamma rays t The twelfth figure with the gamma rays ten irradiation dose rate but the grafting rate shadow. The product of the cobalt 60 irradiation time and the grafting rate shadow of the product produced by the 5-ray method. The first sixty of the products made

Claims (1)

200416047 VI. Scope of Patent Application '^ ~ 一 ~ ---: 喰? 3 ί! A method for preparing dressings, using a non-woven fabric as a substrate, dipping ^ and / or isopropylpropenamide or its monomers in solution ^ immersing the solution with gamma-ray high-energy radiation Non-woven = The above monomers are graft-polymerized on the non-woven fabric, and then dried in the shade to obtain a polymer dressing for burns. π'xian 2 ·: A method for preparing a burn and scald dressing, which uses a non-woven fabric as a substrate and is immersed in a solution of acrylic acid and / or isopropylacrylamide or its analogue monomer, and after 1 to 2 days Take it out, and then irradiate the soaked non-woven fabric with ϋν light to graft polymerize the monomer onto the non-woven fabric, and then clean and dry it to obtain a polymer dressing for burns. Month '3 · According to the preparation method of the first or second scope of the patent application, the monomer concentration is less than 50% ^. /, 4. According to the preparation method of item 1 or item 2 of the scope of the patent application, the monomer solution concentration contains a photoinitiator. 5. The preparation method according to item 4 of the scope of the patent application, where the soluble oil concentration of the photoinitiator is less than 5%. &lt; 6 · The preparation method according to item 1 of the scope of application for patent, whose gamma-ray high-energy irradiation irradiation dose is 5kGy ~ 60kGy, and the irradiation time is 0 ~ 10 hours for the monomer and non-woven graft polymerization reaction. . 7 · According to the preparation method of the scope of patent application No. 2, the order of light irradiation time is 10 to 100 minutes to carry out the graft polymerization reaction of the monomer and the non-woven fabric. Page 22