TR202021404A2 - KITOSAN POLYMER, GRANOLA WITH NANOPARTICULES ENCAPSULATED ROSEMARY AND OLIVE LEAF EXTRACTS - Google Patents

Abstract

The invention includes oatmeal, rice hazelnut, rice peanut, honey, water, dried banana, molasses, drop chocolate, olive oil, rosemary extract encapsulated, and rosemary encapsulated with chitosan polymer nanoparticles, which can be easily consumed at every meal. It relates to granola containing olive leaf extracts.

Description

DESCRIPTION ENCAPSULATED WITH KITOSAN POLYMER NANOPARTICLES GRANOLA WITH ROSEMENT AND OLIVE LEAF EXTRACTS Technical Area Invention, rosemary and olive leaves, which are beneficial for human health, have numerous benefits. encapsulated with chitosan polymer nanoparticles formed by the addition of extracts It relates to granola containing rosemary and olive leaf extracts.

Invention Background Eating habits of people in the face of accelerating life as a result of technology is changing day by day. People especially in the morning, like work or school In order to be able to reach the places they will go, they will consume both healthily and easily. they have breakfast with granolas as food. Because it's dry in granola useful foods such as fruit, oily seeds and oats can be found and quickly can be consumed.

The amount of fiber in the oats in granola provides our body. the benefits are many. Thanks to the fibers it contains, it also helps our body's digestive system. organizes. Refined sugar is also found in granola, such as cornflakes. does not exist. Thanks to natural sugar ingredients such as granola, honey or molasses, It does not tire the digestive system of the human body.

In addition, consumption of rosemary and olive leaves, which have numerous benefits for the human body. It is very important for health. These 'products' in the market are generally consumed as tea. and everyone does not use these teas because they do not like the taste. or at meals It is used as a spice and is preferred because it has an intense aroma. is not done.

Rosemary contains many vitamins and minerals and is also a very powerful It is an antioxidant. The benefits of rosemary for the human body can be listed as follows: . It facilitates digestion.

It strengthens the immune system.

Regulates blood sugar levels.

It increases blood circulation.

Helps reduce gas and bloating.

It supports bowel movements.

It prevents cancer by protecting cells from free radical damage.

It prevents obesity.

It strengthens the memory.

It prevents inflammation.

It is good for chronic pain.

It eliminates problems such as dryness of the scalp, dandruff and shedding.

It promotes hair growth.

Improves liver functions.

It calms the nerves and helps to reduce the symptoms of depression.

Olive has been an alternative for centuries with its fruit, leaves and oil. type used. Because olive leaves carry a high amount of antibacterial, It has a positive effect on strengthening the immune system. human olive leaf The benefits for the body are as follows: It helps to strengthen the immune system.

Due to its anti-bacterial properties, it cleans the bacteria in the body.

It enables cells to regenerate.

It helps to relax the digestive system.

It gives energy.

It is perfect for lowering bad cholesterol.

It has a positive effect on heart health.

It is the solution to chronic fatigue.

It has weight loss properties.

It prevents premature aging.

It supports the rapid healing of wounds.

It helps in the treatment of allergies.

The fire goes down.

It helps to increase blood flow. o Contains antioxidants such as breast, liver and prostate cancer It has a positive effect on cancer. 0 Prevents muscle spasms.

Rosmarinic acid, carnozole and carnosic acid, which are powerful antioxidants in rosemary. contains acid. Especially showing the effects of rosmarinic acid on health. there are many studies. How can I improve the complications of diabetes? (Runtuwene, Joshua et al. “Rosmarinic acid ameliorates hyperglycemia and insulin) sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and Runtuwenw, Jshue et al.), anti-inflammatory and anti-apoptosis effect (Wang, W. J., Cheng, M. H., Lin, J. H., & Wang, C. 8. (2017). Effect of a rosmarinic acid supplemented hemodiaiysis fluid on inflammation of human vascuiar endothelial cells Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 50(12), e6145. Wang W.J et al. and Joardar, S., Dewanjee, S., Bhowmick, 8, Dua, T. K., Das, S., Saha, A., & De Feo, V. (2019).

Rosmarinic Acid Attenuates Cadmium-lnduced Nephrotoxicity via Inhibition of Oxidative Stress, Apoptosis, inflammation and Fibrosis. international journal of molecular sciences, 20(8), 2027. Joardar S et al.), antibacterial (Zhu F, Wang J, Takano H, Xu Z, Nishiwaki H, Yonekura L, Yang R, Tamura H. Rosmarinic acid and its ester derivatives for enhancing antibacterial, d-glucosidase inhibitory, and Iipid et al.), antimicrobial, anti tum'or (Bittner Fialova, S., Kello, M., Coma, M., Slobodni'kova, L., Drobna, E., Holkova, l., Garajova, M., Mrva, M., Zachar, V., & Luke, M. (2019). Derivatization of Rosmarinic Acid Enhances its in vitro Antitumor, Antimicrobial and Antiprotozoal Properties. Molecules (Basel, Switzerland), 24(6), 1078. Bittner Fialova S et al.) anticancer effects (Moore, J., Yousef, M., & Tsiani, E. (2016). Anticancer Effects of Rosemary (Rosmarinus officinalis L.) Extract and Rosemary Extract Polyphenols. Nutrients, 8(11), 731. Moore J et al; Jang, Y.G., Hwang, K. A., & Choi, K. C. (2018). Rosmarinic Acid, a Component of Rosemary Tea, Induced the Cell Cycle Arrest and Apoptosis through Modiation of HDAC2 Expression in Prostate Cancer Cell Lines. Nutrients, 10(11), 1784. Jang YG et al.), against neurodegeneration (Habtemariam S. (2018). Molecular Pharmacology of Rosmarinic and Salvianolic Acids: Potential Seeds for Alzheimer's and Vascular Dementia Drugs. International journal of molecular sciences, 19(2), 458.

There are many studies on the effects of Habtemariam S.).

The main component of olive leaf extract is Oleuropein. Oleuropein, Oleaceae, It belongs to the secoiridoids, abundant in Gentianaceae, Cornaleae and many other plants.

Iridoids and secoiridoids are generally glycosidic-binding and are various types of terpenes. Compounds produced from the secondary metabolism of indole alkaloids as precursors (Omar, S. H. (2010). Oleuropein in olive and its pharmacological effects. Scientia anti-inflammatory, antiviral (Lee-Huang, S., Zhang, L., Huang, P. L., Chang, Y. T., & Huang, P. L. ( and modulation of host cell gene expression by HIV-1 infection and OLE treatment. biochemical and antimicrobial and anti-proliferative properties and cardiovascular diseases, diabetes Mellitus, neurological diseases, skin diseases and cancers exhibits biological activities such as effects (Rigacci, S., & Stefani, M. (2016). properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans. International journal of molecular sciences, 17(6), 843. Rigacci and Stefani, 2016).

In addition to all these beneficial properties of rosemary and olive leaf extracts, they It has a unique, intense and spicy aroma. Although these aromas Although it is preferred to be consumed as a meal or as a meal, sweet foods such as granola It does not suit many people's tastes. existing direct or any encapsulated form with added rosemary and olive leaf extract There is no granola.

The invention is based on the extracts of rosemary and olive leaves, which are very important for health. It allows it to be used as a supplement in granolas. Thus, a healthy product, as well as rosemary and olive leaf extracts, using chitosan polymers. It is given in encapsulated form with nanoparticles and it does not disturb the consumer in granola. It ensures that it does not leave an unpleasant aroma.

The invention is taking the necessary rosemary and olive leaf which is beneficial for the human body. It is created by adding to granola products and is against many diseases. encapsulated with chitosan polymer nanoparticles, which can be a protective feature It relates to granola containing rosemary and olive leaf extracts.

Rosemary and olive leaf encapsulated with chitosan polymer nanoparticles Since the granola product containing extracts is prepared at very low temperatures, such as 30-70 °C, It does not cause any deterioration in the active ingredients of the materials.

Thus, when the product is used, beneficial nutrients for the human body are contained. can be consumed in a healthy way.

The structural and characteristic features of the invention and all its advantages are detailed below. will be understood more clearly by the explanation and therefore this Considering these figures and detailed explanation, the evaluation needs to be done.

Detailed Description of the Invention Invention, rosemary and olive leaves, which are beneficial for human health, have numerous benefits. encapsulated with chitosan polymer nanoparticles formed by the addition of extracts Granola with rosemary and olive leaf extracts is detailed below. are described in the disclosure without any limiting effect.

The present invention is based on rosemary and encapsulated chitosan polymer nanoparticles. Ingredients for the preparation of granola containing olive leaf extracts and The weight ratios are as follows: 0 10-50% oatmeal, . 2-20% Pistachio Rice, - 2-20% honey, 0 2-20% water, 0 5-15% dried banana, - 5-20% molasses, 0 3-20% chocolate chips, In the invention in question, firstly, chitosan is encapsulated with polymer nanoparticles. Rosemary extract is prepared. Water during the preparation process is in the figure; Rosemary entrance is provided, Physical control of rosemary quality compliance is made, lowering is done, Grinding is done, -70 °C, 1-5 hours ultrasonic extraction, Filtration is done, Encapsulation is done with chitosan, 100-1000 RPM centrifugation process is done, -70 °C, 24-120 hours drying process, Grinding is done, Weighing process is done, Homogenization is done with powder homogenizer.

Then, olive leaf encapsulated with chitosan polymer nanoparticles The process of preparing the extract is done. The preparation process is as follows; Olive leaf input is provided, Physical control of olive leaf quality suitability is made, it is ensured to be lowered, Grinding is done, -70 °C, 1-5 hours ultrasonic extraction, Filtration is done, Chitosan polymers by ionic gelation method of olive leaf extract encapsulation is done, 100-1000 RPM centrifugation process is done, 0 Grinding is done, 0 Weighing process is done, . Homogenization is done with powder homogenizer.

With rosemary extract encapsulated with prepared chitosan polymer nanoparticles Olive leaf extract encapsulated with chitosan polymer nanoparticles is mixed. Then, oatmeal prepared in certain proportions, rice hazelnut, rice nuts, honey, water, dried banana, molasses, chocolate chips, olive oil, encapsulated with granola containing rosemary extract and encapsulated olive leaf extract It is combined so that it becomes the final product and in a healthy way. can be consumed.

The novelty, similar configurations of a person skilled in the art revealed in the invention. and/or using this structuring in the related technique. It is clear that it can be applied to other fields with similar purposes. So like this structuring is one of the criteria of innovation and especially overcoming the known state of the technique. It is also obvious that it will be lacking.

Claims (3)

REQUESTS 1. The invention relates to granola containing rosemary and olive leaf extracts encapsulated with chitosan polymer nanoparticles, which meets the need for rosemary and olive leaf extracts in a daily portion. - 10-50% oatmeal, - 2-20% rice hazelnut, - 2-20% rice nut, 0 2-20% honey, 0 2-20% water, 0 5-15% dry banana, 0 5-20% molasses, 0 3-20% chocolate drops, 0 1-5% olive oil, 0 0.01-1% encapsulated rosemary extract, - 0.01-1% encapsulated It is characterized by the fact that it contains olive leaf extract in proportions. 2. Preparation of rosemary extract, related to granola containing rosemary and olive leaf extract encapsulated with chitosan polymer nanoparticles; o Rosemary input is provided, 0 Physical check of rosemary quality conformity is done, reduction is done, - Grinding is done, 0 30-70 °C, 1-5 hours ultrasonic extraction, - Filtration is done, 0 Encapsulation is done with Chitosan, 0 100-1000 RPM centrifugation is done, 0 Grinding is done, Weighing is done, It is homogenizing with powder homogenizer. 3. Preparation of olive leaf extract, related to granola containing rosemary and olive leaf extract encapsulated with chitosan polymer nanoparticles; Olive leaf inlet is provided, Physical control of olive leaf quality compatibility is made, it is reduced, Grinding is done, 30-70 °C, 1-5 hours ultrasonic extraction, Filtration is done, Chitosan polymers are encapsulated by ionic gelation method of olive leaf extract, 100 -1000 RPM centrifugation is done, 30-70 oC, 24-120 hours drying process is done, Grinding is done, weighing is done, It is homogenizing with powder homogenizer.