TR201901013T4 - 4-imidazopyridazin-1-yl-benzamides and 4-imidazotriazin-1-yl-benzamides as BTK inhibitors. - Google Patents
4-imidazopyridazin-1-yl-benzamides and 4-imidazotriazin-1-yl-benzamides as BTK inhibitors. Download PDFInfo
- Publication number
- TR201901013T4 TR201901013T4 TR2019/01013T TR201901013T TR201901013T4 TR 201901013 T4 TR201901013 T4 TR 201901013T4 TR 2019/01013 T TR2019/01013 T TR 2019/01013T TR 201901013 T TR201901013 T TR 201901013T TR 201901013 T4 TR201901013 T4 TR 201901013T4
- Authority
- TR
- Turkey
- Prior art keywords
- benzamides
- imidazotriazin
- imidazopyridazin
- btk inhibitors
- formula
- Prior art date
Links
- 229940124291 BTK inhibitor Drugs 0.000 title 1
- NBOUQRHNEKKMCI-UHFFFAOYSA-N N1(N=CC=C2C1=NC=N2)C1=CC=C(C(=O)N)C=C1 Chemical class N1(N=CC=C2C1=NC=N2)C1=CC=C(C(=O)N)C=C1 NBOUQRHNEKKMCI-UHFFFAOYSA-N 0.000 title 1
- RFMXXXSWDWZODI-UHFFFAOYSA-N N1(N=NC=C2C1=NC=N2)C1=CC=C(C(=O)N)C=C1 Chemical class N1(N=NC=C2C1=NC=N2)C1=CC=C(C(=O)N)C=C1 RFMXXXSWDWZODI-UHFFFAOYSA-N 0.000 title 1
- 102000001714 Agammaglobulinaemia Tyrosine Kinase Human genes 0.000 abstract 2
- 108010029445 Agammaglobulinaemia Tyrosine Kinase Proteins 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- -1 pyridine ring compound Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Mevcut buluş, formüle (I) göre 6-5 üyeli kaynaşık piridin halkası bileşikleriyle veya bunların farmasötik olarak kabul edilebilir tuzlarıyla veya bu bileşikleri ihtiva eden farmasötik bileşimlerle ve bunların terapide kullanımlarıyla ilgilidir. Özellikle, mevcut buluş, 6-5 üyeli bir kaynaşık piridin halkası bileşiğinin, formül I'e göre Bruton Tirozin Kinaz (BTK) aracılı bozuklukların tedavisinde kullanımı ile ilgilidir.The present invention relates to 6-5 membered fused pyridine ring compounds according to formula (I) or their pharmaceutically acceptable salts or pharmaceutical compositions containing these compounds and their use in therapy. In particular, the present invention relates to the use of a 6-5 membered fused pyridine ring compound in the treatment of Bruton Tyrosine Kinase (BTK) mediated disorders according to formula I.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161509397P | 2011-07-19 | 2011-07-19 | |
| EP11174578 | 2011-07-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201901013T4 true TR201901013T4 (en) | 2019-02-21 |
Family
ID=67956153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2019/01013T TR201901013T4 (en) | 2011-07-19 | 2012-07-11 | 4-imidazopyridazin-1-yl-benzamides and 4-imidazotriazin-1-yl-benzamides as BTK inhibitors. |
Country Status (8)
| Country | Link |
|---|---|
| CY (1) | CY1121174T1 (en) |
| LT (2) | LT3689878T (en) |
| ME (1) | ME03310B (en) |
| NI (1) | NI201400004A (en) |
| NL (1) | NL301097I2 (en) |
| NO (1) | NO2021016I1 (en) |
| PT (1) | PT2734522T (en) |
| TR (1) | TR201901013T4 (en) |
-
2012
- 2012-07-11 LT LTEP19215783.2T patent/LT3689878T/en unknown
- 2012-07-11 PT PT12733505T patent/PT2734522T/en unknown
- 2012-07-11 ME MEP-2019-4A patent/ME03310B/en unknown
- 2012-07-11 TR TR2019/01013T patent/TR201901013T4/en unknown
-
2014
- 2014-01-17 NI NI201400004A patent/NI201400004A/en unknown
-
2019
- 2019-01-22 CY CY20191100084T patent/CY1121174T1/en unknown
-
2021
- 2021-03-22 NL NL301097C patent/NL301097I2/en unknown
- 2021-03-24 LT LTPA2021004C patent/LTC2734522I2/en unknown
- 2021-04-09 NO NO2021016C patent/NO2021016I1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT2734522T (en) | 2019-02-04 |
| LTPA2021004I1 (en) | 2021-04-12 |
| NI201400004A (en) | 2014-10-10 |
| CY1121174T1 (en) | 2020-05-29 |
| LT3689878T (en) | 2021-11-25 |
| NO2021016I1 (en) | 2021-04-09 |
| ME03310B (en) | 2019-10-20 |
| NL301097I2 (en) | 2021-04-12 |
| NL301097I1 (en) | 2021-03-24 |
| LTC2734522I2 (en) | 2022-09-26 |
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