TR201712406A2 - Probiyotik Yüklü Mikrokapsüller Ve Bunların Üretimi - Google Patents

Probiyotik Yüklü Mikrokapsüller Ve Bunların Üretimi Download PDF

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Publication number
TR201712406A2
TR201712406A2 TR2017/12406A TR201712406A TR201712406A2 TR 201712406 A2 TR201712406 A2 TR 201712406A2 TR 2017/12406 A TR2017/12406 A TR 2017/12406A TR 201712406 A TR201712406 A TR 201712406A TR 201712406 A2 TR201712406 A2 TR 201712406A2
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TR
Turkey
Prior art keywords
probiotic
production
loaded microcapsules
microcapsules
loaded
Prior art date
Application number
TR2017/12406A
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English (en)
Inventor
Berber Buse
Original Assignee
Nanomik Biyoteknoloji A S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanomik Biyoteknoloji A S filed Critical Nanomik Biyoteknoloji A S
Priority to TR2017/12406A priority Critical patent/TR201712406A2/tr
Priority to PCT/TR2018/050434 priority patent/WO2019125332A2/en
Priority to EP18891625.8A priority patent/EP3672640A4/en
Priority to US16/636,342 priority patent/US11464811B2/en
Publication of TR201712406A2 publication Critical patent/TR201712406A2/tr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
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    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
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Abstract

Buluş, probiyotiklerin kitosan-aljinat polimerleri ile mikroenkapsüle edilmiş formunu üretme yöntemi, bu yöntemle elde edilen probiyotik yüklü mikrokapsüller ve bunların gıda, tarım ve kozmetikte kullanımı ile ilgilidir. Bu mikrokapsüller; üzerine uygulanan üründe renk ve görünüşte herhangi bir değişiklik yapmadığı gibi, antifungal ve anti-mikotoksin özelliklerine sahiptir.
TR2017/12406A 2017-08-21 2017-08-21 Probiyotik Yüklü Mikrokapsüller Ve Bunların Üretimi TR201712406A2 (tr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
TR2017/12406A TR201712406A2 (tr) 2017-08-21 2017-08-21 Probiyotik Yüklü Mikrokapsüller Ve Bunların Üretimi
PCT/TR2018/050434 WO2019125332A2 (en) 2017-08-21 2018-08-15 Microcapsules loaded with probiotics and production thereof
EP18891625.8A EP3672640A4 (en) 2017-08-21 2018-08-15 PROBIOTIC-LOADED MICROCAPSULES AND THEIR PRODUCTION
US16/636,342 US11464811B2 (en) 2017-08-21 2018-08-15 Microcapsules loaded with probiotics and production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2017/12406A TR201712406A2 (tr) 2017-08-21 2017-08-21 Probiyotik Yüklü Mikrokapsüller Ve Bunların Üretimi

Publications (1)

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TR201712406A2 true TR201712406A2 (tr) 2019-03-21

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TR2017/12406A TR201712406A2 (tr) 2017-08-21 2017-08-21 Probiyotik Yüklü Mikrokapsüller Ve Bunların Üretimi

Country Status (4)

Country Link
US (1) US11464811B2 (tr)
EP (1) EP3672640A4 (tr)
TR (1) TR201712406A2 (tr)
WO (1) WO2019125332A2 (tr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114794466A (zh) * 2022-04-08 2022-07-29 广州正明后生元科技有限公司 一种后生元及其精制方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2580310A (en) * 2018-12-24 2020-07-22 Univ Cape Town A probiotic feed composition and a process for making the composition
CN110564874B (zh) * 2019-08-08 2022-10-14 河北省食品检验研究院（国家果类及农副加工产品质量监督检验中心、河北省食品安全实验室） 一种针对发酵乳中以葡萄糖杆菌为主的系列杂菌污染的高精度特异性数字pcr检测方法
CN111742903A (zh) * 2020-06-22 2020-10-09 黄丽 一种控制新疆牲畜养殖场所卫生害虫数量的方法
CN111925972B (zh) * 2020-09-09 2022-04-05 天津市农业科学院 一种希氏乳杆菌及其应用
CN112544977B (zh) * 2020-11-03 2022-02-18 国家粮食和物资储备局科学研究院 一种多层包被益生菌微胶囊的制备方法
CN112715948A (zh) * 2020-12-17 2021-04-30 新希望乳业股份有限公司 一种高活性益生菌晶球及其制备方法和应用
CN113632988B (zh) * 2021-08-09 2023-09-08 正当年医药科技(广州)有限公司 一种益生菌包埋微囊的制备方法
CN116790449B (zh) * 2023-08-21 2023-10-27 三亚中国农业科学院国家南繁研究院 同时提高乳酸和苯乳酸产量的发酵菌组合物及应用
CN117598396B (zh) * 2024-01-23 2024-04-05 山东健源生物科技有限公司 一种提高益生菌抗逆性的微胶囊及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060008511A1 (en) 2004-07-08 2006-01-12 Jhy-Jhu Lin Probiotic products for pet applications
US20070048295A1 (en) * 2005-08-23 2007-03-01 Ming-Ju Chen Method for preparing alginate capsules
CN101319210A (zh) * 2007-06-08 2008-12-10 中国科学院大连化学物理研究所 一种微生物的固定化方法
KR101000952B1 (ko) 2008-03-19 2010-12-13 주식회사 키토라이프 알긴산과 저분자량 수용성 키토산을 이용한 유산균미세입자의 제조방법
EP2248908A1 (en) 2009-05-05 2010-11-10 Eurolactis Group S.A. Probiotic microorganisms isolated from donkey milk
KR20100092923A (ko) 2010-08-03 2010-08-23 주식회사 키토라이프 알긴산과 저분자량 수용성 키토산을 이용한 유산균 미세입자의 제조방법

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114794466A (zh) * 2022-04-08 2022-07-29 广州正明后生元科技有限公司 一种后生元及其精制方法
CN114794466B (zh) * 2022-04-08 2023-07-21 广州正明后生元科技有限公司 一种后生元及其精制方法

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