TR201111589A2 - Tiotropium bromide anhydrous crystal form. - Google Patents

Tiotropium bromide anhydrous crystal form.

Info

Publication number
TR201111589A2
TR201111589A2 TR2011/11589A TR201111589A TR201111589A2 TR 201111589 A2 TR201111589 A2 TR 201111589A2 TR 2011/11589 A TR2011/11589 A TR 2011/11589A TR 201111589 A TR201111589 A TR 201111589A TR 201111589 A2 TR201111589 A2 TR 201111589A2
Authority
TR
Turkey
Prior art keywords
tiotropium bromide
crystal form
anhydrous crystal
bromide anhydrous
tiotropium
Prior art date
Application number
TR2011/11589A
Other languages
Turkish (tr)
Inventor
Bi̇lgi̇ç Mahmut
Blatter Fritz
Rödel Eva
Original Assignee
Bi̇lgi̇ç Mahmut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from TR2011/02068A external-priority patent/TR201102068A2/en
Application filed by Bi̇lgi̇ç Mahmut filed Critical Bi̇lgi̇ç Mahmut
Priority to TR2011/11589A priority Critical patent/TR201111589A2/en
Priority to PCT/TR2012/000050 priority patent/WO2012118462A1/en
Priority to EP12716718.7A priority patent/EP2681213A1/en
Publication of TR201111589A2 publication Critical patent/TR201111589A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Abstract

Mevcut buluş, Tiotropyum bromür içeren kristal maddeye ve söz konusu maddenin üretiminde kullanılacak prosese ilişkindir.The present invention relates to the crystalline substance containing Tiotropium bromide and the process to be used in the manufacture of said substance.

TR2011/11589A 2011-03-03 2011-11-23 Tiotropium bromide anhydrous crystal form. TR201111589A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
TR2011/11589A TR201111589A2 (en) 2011-03-03 2011-11-23 Tiotropium bromide anhydrous crystal form.
PCT/TR2012/000050 WO2012118462A1 (en) 2011-03-03 2012-03-05 Anhydrous crystalline form of tiotropium bromide
EP12716718.7A EP2681213A1 (en) 2011-03-03 2012-03-05 Anhydrous crystalline form of tiotropium bromide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2011/02068A TR201102068A2 (en) 2011-03-03 2011-03-03 Crystalline substances containing tiotropium bromide
TR2011/11589A TR201111589A2 (en) 2011-03-03 2011-11-23 Tiotropium bromide anhydrous crystal form.

Publications (1)

Publication Number Publication Date
TR201111589A2 true TR201111589A2 (en) 2012-09-21

Family

ID=46000280

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2011/11589A TR201111589A2 (en) 2011-03-03 2011-11-23 Tiotropium bromide anhydrous crystal form.

Country Status (3)

Country Link
EP (1) EP2681213A1 (en)
TR (1) TR201111589A2 (en)
WO (1) WO2012118462A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014042605A1 (en) * 2012-09-11 2014-03-20 Mahmut Bilgic New tiotropium bromide crystalline form

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (en) 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Esters of thienyl carboxylic acids with amino alcohols, their quaternization products, processes for their preparation and medicaments containing them
DK1401445T3 (en) * 2001-06-22 2006-11-27 Boehringer Ingelheim Pharma Crystalline anticholinergic, method of preparing it and using it to prepare a drug
SI1682542T1 (en) * 2003-11-03 2010-04-30 Boehringer Ingelheim Int Novel crystalline anhydride with anticholinergic effect
CN1271073C (en) * 2004-10-26 2006-08-23 江苏正大天晴药业股份有限公司 Crystalline anti-cholinergic tiotropium crystal
SI1881980T1 (en) * 2005-05-02 2012-12-31 Boehringer Ingelheim International Gmbh Novel crystalline forms of tiotropium bromide
ES2384486T3 (en) * 2005-12-19 2012-07-05 Sicor, Inc. New form of tiotropium bromide and procedure for its preparation
IN2012DN00968A (en) * 2009-08-07 2015-04-10 Generics Uk Ltd
TR201007108A2 (en) * 2010-08-25 2012-03-21 B�Lg�� Mahmut New tiotropium bromide crystal and production method.

Also Published As

Publication number Publication date
WO2012118462A1 (en) 2012-09-07
EP2681213A1 (en) 2014-01-08

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