TR200200600T2 - The process for the production of bone prosthesis material through the processing of natural bone tissue. - Google Patents

The process for the production of bone prosthesis material through the processing of natural bone tissue.

Info

Publication number
TR200200600T2
TR200200600T2 TR2002/00600T TR200200600T TR200200600T2 TR 200200600 T2 TR200200600 T2 TR 200200600T2 TR 2002/00600 T TR2002/00600 T TR 2002/00600T TR 200200600 T TR200200600 T TR 200200600T TR 200200600 T2 TR200200600 T2 TR 200200600T2
Authority
TR
Turkey
Prior art keywords
bone
tissue
viruses
natural bone
production
Prior art date
Application number
TR2002/00600T
Other languages
Turkish (tr)
Inventor
Faurie Michel
Roine Corinne
Original Assignee
Ost-Developpement
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ost-Developpement filed Critical Ost-Developpement
Publication of TR200200600T2 publication Critical patent/TR200200600T2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Abstract

Bulus tip I kolajenden dogal kemik dokusunu muhafaza ederek kemik greft parçalari üretmeyi önermektedir. Islem dogal kemik malzemesini, özellikle uygun tarzda kesilmis insan femür baslarinin malzemesini bir lipitsizlestirme ve saflastirma muamelesine tabi tutmaktir; islem, öncesinde basinçli su ile duyarlilastirma asamasi ve ardindan üre ile ekstraksiyon asamasi yürütülen en az bir aseton ile ekstraksiyon asamasi ihtiva eder; bu asamalarin amaci kemik malzemesinden tüm hastalik bulastirici ajanlari, özellikle insan dokularindan bulasabilir formda mevcut olmasindan kaygilanabilecek hepatit, poliomiyelit veya AIDS (HIV) virüsleri gibi virüsleri ve Creutzfeld-Jacob hastaliginin ve benzer süngerimsi ansefalopatik hastaliklarin prionlari gibi konvansiyonel olmayan ajanlari temizlemektir.The invention proposes to produce bone graft fragments by preserving natural bone tissue from type I collagen. The process is to subject the natural bone material, especially the material of appropriately cut human femoral bass, to a lipid removal and purification treatment; The process includes at least one acetone extraction step, followed by a pressure water sensitization step followed by urea extraction step; The purpose of these stages is to clean all disease infectious agents from bone material, viruses such as hepatitis, poliomyelitis or AIDS (HIV) viruses, which may be worried because they are present in human tissue, and unconventional agents such as Creutzfeld-Jacob disease and similar spongy encephalopathic diseases.

TR2002/00600T 1999-09-10 2000-09-07 The process for the production of bone prosthesis material through the processing of natural bone tissue. TR200200600T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9911809A FR2798294B1 (en) 1999-09-10 1999-09-10 PROCESS FOR THE MANUFACTURE OF A BONE PROSTHESIS MATERIAL BY TREATING A NATURAL BONE TISSUE

Publications (1)

Publication Number Publication Date
TR200200600T2 true TR200200600T2 (en) 2002-06-21

Family

ID=9550097

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00600T TR200200600T2 (en) 1999-09-10 2000-09-07 The process for the production of bone prosthesis material through the processing of natural bone tissue.

Country Status (6)

Country Link
EP (1) EP1210134A1 (en)
KR (1) KR20020043578A (en)
AU (1) AU7299400A (en)
FR (1) FR2798294B1 (en)
TR (1) TR200200600T2 (en)
WO (1) WO2001019424A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10157182A1 (en) * 2001-11-22 2003-06-05 Matricel Gmbh Process for the treatment of materials of biological origin and elastin product
WO2004067050A1 (en) 2003-01-28 2004-08-12 Osteotech, Inc. Tissue pathogen inactivation/removal process
AT413075B (en) * 2003-02-25 2005-11-15 Austria Wirtschaftsserv Gmbh METHOD FOR PRODUCING A BONE IMPLANT MATERIAL AND DEVICE FOR CARRYING OUT THIS METHOD
US8685092B2 (en) * 2005-10-27 2014-04-01 Andrey Fedorovich Panasyuk Material for osteoplasty and tissue engineering
KR100771058B1 (en) 2007-05-18 2007-10-30 이희영 Scaffolds removed lipid for human volume replacement or cell culture and use thereof
FR3110386A1 (en) 2020-05-20 2021-11-26 Univ Paris Xiii Paris-Nord Villetaneuse POROUS BONE SUBSTITUTION MATERIAL

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1169612B (en) * 1961-03-30 1964-05-06 Braun Fa B Method of preserving bone grafts
FR2134695A1 (en) * 1971-04-30 1972-12-08 Mini En Electric Homo-implants - made of human bone for treating parodontopathy
FR2654625B1 (en) * 1989-11-22 1992-02-21 Transphyto Sa PROCESS FOR MANUFACTURING A MATERIAL FOR OSTEOPLASTY FROM A NATURAL BONE TISSUE AND MATERIAL OBTAINED BY THIS PROCESS.
US5513662A (en) * 1991-12-31 1996-05-07 Osteotech, Inc. Preparation of bone for transplantation

Also Published As

Publication number Publication date
AU7299400A (en) 2001-04-17
FR2798294A1 (en) 2001-03-16
WO2001019424A1 (en) 2001-03-22
FR2798294B1 (en) 2001-10-12
KR20020043578A (en) 2002-06-10
EP1210134A1 (en) 2002-06-05

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