TR200000407T2 - Etken madde olarak scopolaminbase içeren transdermal terapötik sistem - Google Patents
Etken madde olarak scopolaminbase içeren transdermal terapötik sistemInfo
- Publication number
- TR200000407T2 TR200000407T2 TR2000/00407T TR200000407T TR200000407T2 TR 200000407 T2 TR200000407 T2 TR 200000407T2 TR 2000/00407 T TR2000/00407 T TR 2000/00407T TR 200000407 T TR200000407 T TR 200000407T TR 200000407 T2 TR200000407 T2 TR 200000407T2
- Authority
- TR
- Turkey
- Prior art keywords
- scopolaminbase
- therapeutic system
- layer
- active ingredient
- transdermal therapeutic
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 239000010410 layer Substances 0.000 abstract 4
- 239000012790 adhesive layer Substances 0.000 abstract 2
- STECJAGHUSJQJN-UHFFFAOYSA-N N-Methyl-scopolamin Natural products C1C(C2C3O2)N(C)C3CC1OC(=O)C(CO)C1=CC=CC=C1 STECJAGHUSJQJN-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000005038 ethylene vinyl acetate Substances 0.000 abstract 1
- MOYZEMOPQDTDHA-UHFFFAOYSA-N norscopolamine Natural products C1C(C2OC22)NC2CC1OC(=O)C(CO)C1=CC=CC=C1 MOYZEMOPQDTDHA-UHFFFAOYSA-N 0.000 abstract 1
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229920005573 silicon-containing polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Abstract
Scopolaminbase esasli ve esnek olan, ve etken madde geçirmeyen bir ara tabaka, etken madde içeren bir rezervuar tabakasi, bir kumanda diyaframi, sistemin deride sabit olarak yapismasi için bir yapistiricili katman, ve uygulamadan önce çikarilacak olan, yine etken madde geçirmeyen bir koruma folyosu içeren transdermal terapötik sistemin özelligi, Rezervuar tabakasinin ve de yapistiricili katmanin kendinden yapiskanli ve temel polimer olarak aminlere dayanikli silikon polimerden olusmasi, ve kumanda diyaframinin etilen vinil asetat-copolimerden olusmasi, ve Scopolaminbasenin kismen, en azindan rezervuar tabakasinda kristaller seklinde bulunmasidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19738643A DE19738643C2 (de) | 1997-09-04 | 1997-09-04 | Transdermales therapeutisches System mit dem Wirkstoff Scopolaminbase und Verfahren zu seiner Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200000407T2 true TR200000407T2 (tr) | 2000-08-21 |
Family
ID=7841162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/00407T TR200000407T2 (tr) | 1997-09-04 | 1998-08-18 | Etken madde olarak scopolaminbase içeren transdermal terapötik sistem |
Country Status (22)
Country | Link |
---|---|
US (1) | US6537571B1 (tr) |
EP (1) | EP1011674B1 (tr) |
JP (1) | JP3834202B2 (tr) |
KR (1) | KR100549846B1 (tr) |
AT (1) | ATE214606T1 (tr) |
AU (1) | AU738009B2 (tr) |
CA (1) | CA2300339C (tr) |
DE (2) | DE19738643C2 (tr) |
DK (1) | DK1011674T3 (tr) |
ES (1) | ES2174492T3 (tr) |
HK (1) | HK1032194A1 (tr) |
HU (1) | HUP0003480A3 (tr) |
ID (1) | ID24266A (tr) |
IL (1) | IL134418A (tr) |
NO (1) | NO20000894D0 (tr) |
NZ (1) | NZ502873A (tr) |
PL (1) | PL339226A1 (tr) |
PT (1) | PT1011674E (tr) |
SK (1) | SK3052000A3 (tr) |
TR (1) | TR200000407T2 (tr) |
WO (1) | WO1999011265A1 (tr) |
ZA (1) | ZA988052B (tr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050013957A1 (en) * | 2003-07-15 | 2005-01-20 | Boris Leschinsky | Disposable medical article with multiple adhesives for skin attachment |
DE102004020463A1 (de) * | 2004-04-26 | 2005-11-10 | Grünenthal GmbH | Wirkstoffabgabesystem aus einem wirkstoffhaltigen Pflaster und mindestens einem Wirkstoffabgaberegulierungsmittel |
DE102004044578A1 (de) | 2004-09-13 | 2006-03-30 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit einer Haftschicht, Verfahren zum Silikonisieren einer Rückschicht des Systems und Verwendung der Rückschicht |
US20070010550A1 (en) * | 2005-07-08 | 2007-01-11 | The Board Of Regents Of The University Of Texas | Scopolamine to Reduce or Eliminate Hot Flashes, Night Sweats, and Insomnia |
CN101431988A (zh) * | 2006-02-27 | 2009-05-13 | 诺芬药品公司 | 包含东莨菪碱的透皮治疗系统 |
DE102006054732B4 (de) * | 2006-11-21 | 2010-12-30 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren |
KR101572721B1 (ko) | 2013-10-14 | 2015-11-27 | 주식회사 엘지생활건강 | 히오신을 유효 성분으로 함유하는 피부 건조증 또는 피부 장벽 기능 개선용 조성물 |
WO2016168021A1 (en) * | 2015-04-14 | 2016-10-20 | Atossa Genetics, Inc. | Compositions and methods of treatment of breast disorders and estrogen-related disorders |
CA3061284A1 (en) * | 2017-06-26 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing scopolamine and silicone acrylic hybrid polymer |
DE102018118507A1 (de) | 2018-07-31 | 2020-02-06 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Abgabe von Scopolamin ohne Membran |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US35474A (en) * | 1862-06-03 | Improved rocket-harpoon | ||
US3797494A (en) | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
US3903880A (en) * | 1972-08-17 | 1975-09-09 | Alza Corp | Intrauterine device for managing the reproductive process |
US4573996A (en) * | 1984-01-03 | 1986-03-04 | Jonergin, Inc. | Device for the administration of an active agent to the skin or mucosa |
US4655767A (en) * | 1984-10-29 | 1987-04-07 | Dow Corning Corporation | Transdermal drug delivery devices with amine-resistant silicone adhesives |
US4832953A (en) * | 1987-08-13 | 1989-05-23 | Alza Corporation | Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix |
US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
DE3908431A1 (de) * | 1989-03-15 | 1990-09-27 | Lohmann Therapie Syst Lts | Transdermales system mit gestufter wirkstoffabgabe und verwendung fuer die lokale oder systemische wirkstoffverabreichung |
EP0671176B1 (en) | 1993-09-30 | 2001-06-06 | Takiron Co. Ltd. | Percutaneously absorbable preparation |
DE4438989C2 (de) * | 1994-09-16 | 1999-02-25 | Lohmann Therapie Syst Lts | Scopolaminpflaster |
US5714162A (en) * | 1994-09-16 | 1998-02-03 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Scopolamine patch |
WO1997020550A2 (en) | 1995-12-01 | 1997-06-12 | Alza Corporation | Improved method for preventing crystal formation in a dispersion of a liquid in a matrix |
-
1997
- 1997-09-04 DE DE19738643A patent/DE19738643C2/de not_active Expired - Fee Related
-
1998
- 1998-08-18 ES ES98946364T patent/ES2174492T3/es not_active Expired - Lifetime
- 1998-08-18 DK DK98946364T patent/DK1011674T3/da active
- 1998-08-18 WO PCT/EP1998/005224 patent/WO1999011265A1/de active IP Right Grant
- 1998-08-18 IL IL13441898A patent/IL134418A/en not_active IP Right Cessation
- 1998-08-18 JP JP2000508368A patent/JP3834202B2/ja not_active Expired - Lifetime
- 1998-08-18 SK SK305-2000A patent/SK3052000A3/sk unknown
- 1998-08-18 ID IDW20000299A patent/ID24266A/id unknown
- 1998-08-18 TR TR2000/00407T patent/TR200000407T2/tr unknown
- 1998-08-18 US US09/485,912 patent/US6537571B1/en not_active Expired - Lifetime
- 1998-08-18 AU AU93434/98A patent/AU738009B2/en not_active Ceased
- 1998-08-18 DE DE59803454T patent/DE59803454D1/de not_active Expired - Lifetime
- 1998-08-18 CA CA002300339A patent/CA2300339C/en not_active Expired - Lifetime
- 1998-08-18 HU HU0003480A patent/HUP0003480A3/hu unknown
- 1998-08-18 EP EP98946364A patent/EP1011674B1/de not_active Expired - Lifetime
- 1998-08-18 PT PT98946364T patent/PT1011674E/pt unknown
- 1998-08-18 PL PL98339226A patent/PL339226A1/xx unknown
- 1998-08-18 NZ NZ502873A patent/NZ502873A/en unknown
- 1998-08-18 KR KR1020007002299A patent/KR100549846B1/ko not_active IP Right Cessation
- 1998-08-18 AT AT98946364T patent/ATE214606T1/de active
- 1998-09-03 ZA ZA988052A patent/ZA988052B/xx unknown
-
2000
- 2000-02-23 NO NO20000894A patent/NO20000894D0/no not_active Application Discontinuation
- 2000-12-23 HK HK00108393A patent/HK1032194A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2001514226A (ja) | 2001-09-11 |
DK1011674T3 (da) | 2002-07-08 |
JP3834202B2 (ja) | 2006-10-18 |
CA2300339A1 (en) | 1999-03-11 |
DE19738643C2 (de) | 2001-10-04 |
ATE214606T1 (de) | 2002-04-15 |
ES2174492T3 (es) | 2002-11-01 |
HUP0003480A2 (hu) | 2001-02-28 |
IL134418A (en) | 2004-02-19 |
HK1032194A1 (en) | 2001-07-13 |
AU738009B2 (en) | 2001-09-06 |
IL134418A0 (en) | 2001-04-30 |
EP1011674B1 (de) | 2002-03-20 |
ZA988052B (en) | 1999-03-05 |
AU9343498A (en) | 1999-03-22 |
NO20000894L (no) | 2000-02-23 |
KR100549846B1 (ko) | 2006-02-06 |
KR20010023647A (ko) | 2001-03-26 |
EP1011674A1 (de) | 2000-06-28 |
HUP0003480A3 (en) | 2001-03-28 |
ID24266A (id) | 2000-07-13 |
US6537571B1 (en) | 2003-03-25 |
SK3052000A3 (en) | 2000-12-11 |
DE19738643A1 (de) | 1999-03-11 |
CA2300339C (en) | 2007-07-17 |
PL339226A1 (en) | 2000-12-04 |
PT1011674E (pt) | 2002-08-30 |
DE59803454D1 (de) | 2002-04-25 |
WO1999011265A1 (de) | 1999-03-11 |
NZ502873A (en) | 2001-07-27 |
NO20000894D0 (no) | 2000-02-23 |
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