TR200000407T2 - Transdermal therapeutic system with active ingredient scopolaminbase - Google Patents

Transdermal therapeutic system with active ingredient scopolaminbase

Info

Publication number
TR200000407T2
TR200000407T2 TR2000/00407T TR200000407T TR200000407T2 TR 200000407 T2 TR200000407 T2 TR 200000407T2 TR 2000/00407 T TR2000/00407 T TR 2000/00407T TR 200000407 T TR200000407 T TR 200000407T TR 200000407 T2 TR200000407 T2 TR 200000407T2
Authority
TR
Turkey
Prior art keywords
scopolaminbase
therapeutic system
layer
active ingredient
transdermal therapeutic
Prior art date
Application number
TR2000/00407T
Other languages
Turkish (tr)
Inventor
Mller Walter
Original Assignee
Lts Lohmanntherapie-Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmanntherapie-Systeme Ag filed Critical Lts Lohmanntherapie-Systeme Ag
Publication of TR200000407T2 publication Critical patent/TR200000407T2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Abstract

Scopolaminbase esasli ve esnek olan, ve etken madde geçirmeyen bir ara tabaka, etken madde içeren bir rezervuar tabakasi, bir kumanda diyaframi, sistemin deride sabit olarak yapismasi için bir yapistiricili katman, ve uygulamadan önce çikarilacak olan, yine etken madde geçirmeyen bir koruma folyosu içeren transdermal terapötik sistemin özelligi, Rezervuar tabakasinin ve de yapistiricili katmanin kendinden yapiskanli ve temel polimer olarak aminlere dayanikli silikon polimerden olusmasi, ve kumanda diyaframinin etilen vinil asetat-copolimerden olusmasi, ve Scopolaminbasenin kismen, en azindan rezervuar tabakasinda kristaller seklinde bulunmasidir.Transdermal, containing a Scopolaminbase-based and flexible, impervious intermediate layer, a reservoir layer containing the active substance, a control diaphragm, an adhesive layer for the system to adhere permanently to the skin, and an active-impervious protective film that will be removed before application. The characteristic of the therapeutic system is that the reservoir layer and the adhesive layer are self-adhesive and basic polymer made of amine-resistant silicone polymer, and the control diaphragm is composed of ethylene vinyl acetate-copolymer, and the Scopolamin basin is partially crystallized in the reservoir layer.

TR2000/00407T 1997-09-04 1998-08-18 Transdermal therapeutic system with active ingredient scopolaminbase TR200000407T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19738643A DE19738643C2 (en) 1997-09-04 1997-09-04 Transdermal therapeutic system with the active ingredient scopolamine base and process for its preparation

Publications (1)

Publication Number Publication Date
TR200000407T2 true TR200000407T2 (en) 2000-08-21

Family

ID=7841162

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00407T TR200000407T2 (en) 1997-09-04 1998-08-18 Transdermal therapeutic system with active ingredient scopolaminbase

Country Status (22)

Country Link
US (1) US6537571B1 (en)
EP (1) EP1011674B1 (en)
JP (1) JP3834202B2 (en)
KR (1) KR100549846B1 (en)
AT (1) ATE214606T1 (en)
AU (1) AU738009B2 (en)
CA (1) CA2300339C (en)
DE (2) DE19738643C2 (en)
DK (1) DK1011674T3 (en)
ES (1) ES2174492T3 (en)
HK (1) HK1032194A1 (en)
HU (1) HUP0003480A3 (en)
ID (1) ID24266A (en)
IL (1) IL134418A (en)
NO (1) NO20000894L (en)
NZ (1) NZ502873A (en)
PL (1) PL339226A1 (en)
PT (1) PT1011674E (en)
SK (1) SK3052000A3 (en)
TR (1) TR200000407T2 (en)
WO (1) WO1999011265A1 (en)
ZA (1) ZA988052B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050013957A1 (en) * 2003-07-15 2005-01-20 Boris Leschinsky Disposable medical article with multiple adhesives for skin attachment
DE102004020463A1 (en) * 2004-04-26 2005-11-10 Grünenthal GmbH Drug delivery system consisting of a drug-containing patch and at least one Wirkstoffabgaberegulierungsmittel
DE102004044578A1 (en) 2004-09-13 2006-03-30 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system with an adhesive layer, method for siliconizing a backing layer of the system and use of the backing layer
US20070010550A1 (en) * 2005-07-08 2007-01-11 The Board Of Regents Of The University Of Texas Scopolamine to Reduce or Eliminate Hot Flashes, Night Sweats, and Insomnia
CN101431988A (en) * 2006-02-27 2009-05-13 诺芬药品公司 Transdermal therapeutic system comprising scopolamine
DE102006054732B4 (en) * 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system with ion-pair microreservoirs
KR101572721B1 (en) 2013-10-14 2015-11-27 주식회사 엘지생활건강 Composition for improving dry skin or skin barrierfunction comprising hyoscine
AU2016247674A1 (en) * 2015-04-14 2017-10-19 Atossa Genetics Inc. Compositions and methods of treatment of breast disorders and estrogen-related disorders
CN110809466A (en) * 2017-06-26 2020-02-18 罗曼治疗系统股份公司 Transdermal therapeutic system containing hybrid polymer of scopolamine and siloxane acrylic acid
DE102018118507A1 (en) 2018-07-31 2020-02-06 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system for the delivery of scopolamine without a membrane

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US35474A (en) * 1862-06-03 Improved rocket-harpoon
US3797494A (en) 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3903880A (en) * 1972-08-17 1975-09-09 Alza Corp Intrauterine device for managing the reproductive process
US4573996A (en) * 1984-01-03 1986-03-04 Jonergin, Inc. Device for the administration of an active agent to the skin or mucosa
US4655767A (en) * 1984-10-29 1987-04-07 Dow Corning Corporation Transdermal drug delivery devices with amine-resistant silicone adhesives
US4832953A (en) 1987-08-13 1989-05-23 Alza Corporation Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
DE3908431A1 (en) * 1989-03-15 1990-09-27 Lohmann Therapie Syst Lts TRANSDERMAL SYSTEM WITH STAGE SUBSTANCE DELIVERY AND USE FOR LOCAL OR SYSTEMIC DISPENSER
CN1115964A (en) * 1993-09-30 1996-01-31 多喜兰株式会社 Percutaneously absorbable preparation
DE4438989C2 (en) * 1994-09-16 1999-02-25 Lohmann Therapie Syst Lts Scopolamine patches
US5714162A (en) * 1994-09-16 1998-02-03 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Scopolamine patch
EP0863751B1 (en) * 1995-12-01 2001-10-24 Alza Corporation Improved method for preventing crystal formation in a dispersion of a liquid in a matrix

Also Published As

Publication number Publication date
IL134418A0 (en) 2001-04-30
JP3834202B2 (en) 2006-10-18
EP1011674A1 (en) 2000-06-28
KR20010023647A (en) 2001-03-26
ZA988052B (en) 1999-03-05
DK1011674T3 (en) 2002-07-08
ATE214606T1 (en) 2002-04-15
NO20000894D0 (en) 2000-02-23
JP2001514226A (en) 2001-09-11
CA2300339A1 (en) 1999-03-11
ID24266A (en) 2000-07-13
DE19738643A1 (en) 1999-03-11
NO20000894L (en) 2000-02-23
ES2174492T3 (en) 2002-11-01
SK3052000A3 (en) 2000-12-11
WO1999011265A1 (en) 1999-03-11
HUP0003480A2 (en) 2001-02-28
IL134418A (en) 2004-02-19
AU9343498A (en) 1999-03-22
EP1011674B1 (en) 2002-03-20
HK1032194A1 (en) 2001-07-13
KR100549846B1 (en) 2006-02-06
US6537571B1 (en) 2003-03-25
AU738009B2 (en) 2001-09-06
DE59803454D1 (en) 2002-04-25
PT1011674E (en) 2002-08-30
CA2300339C (en) 2007-07-17
PL339226A1 (en) 2000-12-04
NZ502873A (en) 2001-07-27
DE19738643C2 (en) 2001-10-04
HUP0003480A3 (en) 2001-03-28

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