TR199800406T1 - Alipoprotein A-I d�zeylerinin artt�r�lmas� i�in bir tienotriazolodiazepinin kullan�lmas�. - Google Patents
Alipoprotein A-I d�zeylerinin artt�r�lmas� i�in bir tienotriazolodiazepinin kullan�lmas�.Info
- Publication number
- TR199800406T1 TR199800406T1 TR1998/00406T TR9800406T TR199800406T1 TR 199800406 T1 TR199800406 T1 TR 199800406T1 TR 1998/00406 T TR1998/00406 T TR 1998/00406T TR 9800406 T TR9800406 T TR 9800406T TR 199800406 T1 TR199800406 T1 TR 199800406T1
- Authority
- TR
- Turkey
- Prior art keywords
- lmas
- pct
- zeylerinin
- tienotriazolodiazepinin
- kullan
- Prior art date
Links
- POXWDTQUDZUOGP-UHFFFAOYSA-N 1h-1,4-diazepine Chemical compound N1C=CC=NC=C1 POXWDTQUDZUOGP-UHFFFAOYSA-N 0.000 abstract 1
- 102000005666 Apolipoprotein A-I Human genes 0.000 abstract 1
- 108010059886 Apolipoprotein A-I Proteins 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95114163 | 1995-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199800406T1 true TR199800406T1 (en) | 1998-05-21 |
Family
ID=8219597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1998/00406T TR199800406T1 (en) | 1995-09-09 | 1996-08-30 | Alipoprotein A-I d�zeylerinin artt�r�lmas� i�in bir tienotriazolodiazepinin kullan�lmas�. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5854238A (https=) |
| EP (1) | EP0853480B1 (https=) |
| JP (1) | JPH11512107A (https=) |
| KR (1) | KR19990044460A (https=) |
| CN (1) | CN1101680C (https=) |
| AT (1) | ATE230600T1 (https=) |
| AU (1) | AU725249B2 (https=) |
| BR (1) | BR9610390A (https=) |
| CA (1) | CA2230477A1 (https=) |
| DE (1) | DE69625696T2 (https=) |
| DK (1) | DK0853480T3 (https=) |
| ES (1) | ES2188783T3 (https=) |
| TR (1) | TR199800406T1 (https=) |
| WO (1) | WO1997009048A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6518412B1 (en) * | 1997-09-29 | 2003-02-11 | Jean-Louis Dasseux | Gene therapy approaches to supply apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| US6004925A (en) * | 1997-09-29 | 1999-12-21 | J. L. Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| US6253569B1 (en) * | 1999-05-07 | 2001-07-03 | James J. Hall | Portable storage unit for game animals |
| US7723303B2 (en) | 2000-08-24 | 2010-05-25 | The Regents Of The University Of California | Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response |
| US7199102B2 (en) | 2000-08-24 | 2007-04-03 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| US6664230B1 (en) | 2000-08-24 | 2003-12-16 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
| US8568766B2 (en) | 2000-08-24 | 2013-10-29 | Gattadahalli M. Anantharamaiah | Peptides and peptide mimetics to treat pathologies associated with eye disease |
| US7166578B2 (en) | 2000-08-24 | 2007-01-23 | The Regents Of The University Of California | Orally administered peptides synergize statin activity |
| US7144862B2 (en) | 2000-08-24 | 2006-12-05 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
| US7148197B2 (en) * | 2000-08-24 | 2006-12-12 | The Regents Of The University Of California | Orally administered small peptides synergize statin activity |
| US7429593B2 (en) | 2001-09-14 | 2008-09-30 | Shionogi & Co., Ltd. | Utilities of amide compounds |
| US8124625B2 (en) | 2001-09-14 | 2012-02-28 | Shionogi & Co., Ltd. | Method of enhancing the expression of apolipoprotein AI using olefin derivatives |
| EP2168576A3 (en) | 2001-09-14 | 2010-05-26 | Shionogi & Co., Ltd. | Tricyclic compounds for treating dyslipidemia and arteriosclerotic diseases |
| US6930085B2 (en) * | 2002-04-05 | 2005-08-16 | The Regents Of The University Of California | G-type peptides to ameliorate atherosclerosis |
| KR20070089996A (ko) | 2004-12-06 | 2007-09-04 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 세동맥의 구조 및 기능의 개선 방법 |
| EP2195331B1 (en) | 2007-08-28 | 2013-11-20 | Uab Research Foundation | Synthetic apolipoprotein e mimicking polypeptides and methods of use |
| WO2009032702A2 (en) | 2007-08-28 | 2009-03-12 | Uab Research Foundation | Synthetic apolipoprotein e mimicking polypeptides and methods of use |
| ES2448567T3 (es) * | 2008-10-30 | 2014-03-14 | Circomed Llc | Derivados de la tienotriazoldiazepina activos en apo A |
| PL2902030T3 (pl) | 2010-05-14 | 2017-07-31 | Dana-Farber Cancer Institute, Inc. | Związki tienotriazolodiazepinowe do leczenia nowotworu |
| CN103119160B (zh) * | 2010-05-14 | 2016-06-01 | 达那-法伯癌症研究所 | 用于调节代谢的组合物和方法 |
| MX354217B (es) | 2010-05-14 | 2018-02-19 | Dana Farber Cancer Inst Inc | Composiciones y metodos para el tratamiento de leucemia. |
| EP2571875A4 (en) | 2010-05-14 | 2013-10-30 | Dana Farber Cancer Inst Inc | CONTRACEPTIVE COMPOSITIONS FOR MEN AND METHODS OF USE THEREOF |
| US9975896B2 (en) | 2013-07-25 | 2018-05-22 | Dana-Farber Cancer Institute, Inc. | Inhibitors of transcription factors and uses thereof |
| RU2016122654A (ru) | 2013-11-08 | 2017-12-14 | Дана-Фарбер Кэнсер Инститьют, Инк. | Комбинированная терапия злокачественной опухоли с использованием ингибиторов бромодоменового и экстратерминального (вет) белка |
| EP3099677A4 (en) | 2014-01-31 | 2017-07-26 | Dana-Farber Cancer Institute, Inc. | Diaminopyrimidine benzenesulfone derivatives and uses thereof |
| US10793571B2 (en) | 2014-01-31 | 2020-10-06 | Dana-Farber Cancer Institute, Inc. | Uses of diazepane derivatives |
| JP2017506666A (ja) | 2014-02-28 | 2017-03-09 | テンシャ セラピューティクス，インコーポレイテッド | 高インスリン血症に関連した症状の処置 |
| WO2016018665A1 (en) | 2014-07-31 | 2016-02-04 | Uab Research Foundation | Apoe mimetic peptides and higher potency to clear plasma cholesterol |
| CN106793775B (zh) | 2014-08-08 | 2020-06-02 | 达纳-法伯癌症研究所股份有限公司 | 二氢碟啶酮衍生物及其用途 |
| CN106715437A (zh) | 2014-08-08 | 2017-05-24 | 达纳-法伯癌症研究所股份有限公司 | 二氮杂环庚烷衍生物及其用途 |
| KR20170068597A (ko) | 2014-10-27 | 2017-06-19 | 텐샤 세러퓨틱스 인코포레이티드 | 브로모도메인 저해제 |
| WO2016201370A1 (en) | 2015-06-12 | 2016-12-15 | Dana-Farber Cancer Institute, Inc. | Combination therapy of transcription inhibitors and kinase inhibitors |
| RU2018112953A (ru) | 2015-09-11 | 2019-10-14 | Дана-Фарбер Кэнсер Инститьют, Инк. | Ацетамидтиенотриазолодиазепины и пути их применения |
| EP3347021A4 (en) | 2015-09-11 | 2019-07-24 | Dana-Farber Cancer Institute, Inc. | CYANOTHIENOTRIAZOLDIAZEPINE AND USES THEREOF |
| MX2018006499A (es) | 2015-11-25 | 2018-08-01 | Dana Farber Cancer Inst Inc | Inhibidores de bromodominio bivalentes y usos de los mismos. |
| AU2019284971A1 (en) | 2018-06-13 | 2020-12-03 | Worg Pharmaceuticals (Zhejiang) Co., Ltd. | Preparation of condensed triazepine derivatives and their use as BET inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4155913A (en) * | 1973-02-08 | 1979-05-22 | Hoffmann-La Roche Inc. | Thienotriazolodiazepine derivatives |
| PH12303A (en) * | 1973-02-08 | 1979-01-16 | Hoffmann La Roche | Thienotriazolodiazepine derivatives |
| JPS50100096A (https=) * | 1974-01-08 | 1975-08-08 |
-
1996
- 1996-08-30 BR BR9610390A patent/BR9610390A/pt not_active Application Discontinuation
- 1996-08-30 AU AU69303/96A patent/AU725249B2/en not_active Ceased
- 1996-08-30 CN CN96196835A patent/CN1101680C/zh not_active Expired - Fee Related
- 1996-08-30 WO PCT/EP1996/003814 patent/WO1997009048A1/en not_active Ceased
- 1996-08-30 TR TR1998/00406T patent/TR199800406T1/xx unknown
- 1996-08-30 EP EP96930137A patent/EP0853480B1/en not_active Expired - Lifetime
- 1996-08-30 DE DE69625696T patent/DE69625696T2/de not_active Expired - Fee Related
- 1996-08-30 DK DK96930137T patent/DK0853480T3/da active
- 1996-08-30 CA CA002230477A patent/CA2230477A1/en not_active Abandoned
- 1996-08-30 JP JP9510839A patent/JPH11512107A/ja not_active Ceased
- 1996-08-30 ES ES96930137T patent/ES2188783T3/es not_active Expired - Lifetime
- 1996-08-30 KR KR1019980701708A patent/KR19990044460A/ko not_active Ceased
- 1996-08-30 AT AT96930137T patent/ATE230600T1/de not_active IP Right Cessation
- 1996-08-30 US US09/011,819 patent/US5854238A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11512107A (ja) | 1999-10-19 |
| BR9610390A (pt) | 1999-07-06 |
| DE69625696D1 (de) | 2003-02-13 |
| DE69625696T2 (de) | 2003-10-16 |
| DK0853480T3 (da) | 2003-05-05 |
| CN1101680C (zh) | 2003-02-19 |
| MX9801753A (es) | 1998-08-30 |
| CA2230477A1 (en) | 1997-03-13 |
| EP0853480B1 (en) | 2003-01-08 |
| AU725249B2 (en) | 2000-10-12 |
| AU6930396A (en) | 1997-03-27 |
| CN1195989A (zh) | 1998-10-14 |
| WO1997009048A1 (en) | 1997-03-13 |
| EP0853480A1 (en) | 1998-07-22 |
| US5854238A (en) | 1998-12-29 |
| ES2188783T3 (es) | 2003-07-01 |
| KR19990044460A (ko) | 1999-06-25 |
| ATE230600T1 (de) | 2003-01-15 |
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