TNSN98137A1 - CYCLOALKYLES BENZAMIDES STIMULANTS OF HIGH AND LOW GASTROINTESTINAL MOTORITY - Google Patents

CYCLOALKYLES BENZAMIDES STIMULANTS OF HIGH AND LOW GASTROINTESTINAL MOTORITY

Info

Publication number
TNSN98137A1
TNSN98137A1 TNTNSN98137A TNSN98137A TNSN98137A1 TN SN98137 A1 TNSN98137 A1 TN SN98137A1 TN TNSN98137 A TNTNSN98137 A TN TNSN98137A TN SN98137 A TNSN98137 A TN SN98137A TN SN98137 A1 TNSN98137 A1 TN SN98137A1
Authority
TN
Tunisia
Prior art keywords
motority
cycloalkyles
benzamides
stimulants
low gastrointestinal
Prior art date
Application number
TNTNSN98137A
Other languages
French (fr)
Inventor
Olivier Boucheix
Serge Boisa
Thierry Bouyssou
Christian Jeanpetit
Helene Christanaki
Original Assignee
Logeais Labor Jacques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Logeais Labor Jacques filed Critical Logeais Labor Jacques
Publication of TNSN98137A1 publication Critical patent/TNSN98137A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSES DE FORMULE GENERALE (I) SUIVANTE : DANS LAQUELLE R1 EST UN GROUPE ALKYLE EN C1 A C6 OU UN GROUPE CYCLOALKYLE EN C3 A C6, R2 ET R3 SONT H, UN GROUPE ALKYLE EN C1 A C6, OH OU UN GROUPE HYDROXYALKYLE, m = 1 OU 2, ET n = 1,2 OU 3. L'INVENTION CONCERNE EGALEMENT LES COMPOSITIONS PHARMACEUTIQUES CONTENANT CES COMPOSES, ET LEURS UTILISATIONS DANS LE CADRE DU TRAITEMENT DES DYSFONCTIONNEMENTS DU TUBE DIGESTIF HAUT ET BAS. .THE INVENTION CONCERNS COMPOUNDS OF THE FOLLOWING GENERAL FORMULA (I): IN WHICH R1 IS A C1 TO C6 ALKYL GROUP OR A C3 TO C6 CYCLOALKYL GROUP, R2 AND R3 ARE H, A C1 TO C6 ALKYL GROUP, OH OR A HYDROXYALKYL GROUP, m = 1 OR 2, AND n = 1.2 OR 3. THE INVENTION ALSO CONCERNS THE PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, AND THEIR USES IN THE TREATMENT OF HIGH AND LOW DIGESTIVE TUBE DYSFUNCTION. .

TNTNSN98137A 1997-07-25 1998-07-15 CYCLOALKYLES BENZAMIDES STIMULANTS OF HIGH AND LOW GASTROINTESTINAL MOTORITY TNSN98137A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9709478A FR2766486B1 (en) 1997-07-25 1997-07-25 HIGH AND LOW GASTROINTESTINAL MOTOR STIMULATING BENZAMIDE CYCLOALKYLES

Publications (1)

Publication Number Publication Date
TNSN98137A1 true TNSN98137A1 (en) 2005-03-15

Family

ID=9509624

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN98137A TNSN98137A1 (en) 1997-07-25 1998-07-15 CYCLOALKYLES BENZAMIDES STIMULANTS OF HIGH AND LOW GASTROINTESTINAL MOTORITY

Country Status (8)

Country Link
EP (1) EP0998469A1 (en)
AR (1) AR014901A1 (en)
AU (1) AU8867998A (en)
CO (1) CO4990983A1 (en)
FR (1) FR2766486B1 (en)
TN (1) TNSN98137A1 (en)
WO (1) WO1999005133A1 (en)
ZA (1) ZA986632B (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1015921A (en) * 1961-10-06 1966-01-05 Benger Lab Ltd Benzamides
AR216043A1 (en) * 1974-03-21 1979-11-30 Anphar Sa PROCEDURE FOR THE PREPARATION OF 1-BENZOYLAMINE-4-PIPERIDINE DERIVATIVES AND ITS PHYSIOLOGICALLY ACCEPTABLE SALTS
DE3668268D1 (en) * 1985-10-25 1990-02-22 Upjohn Co USE OF CIS-N- (2-AMINOCYCLOALIPHATIC) Benzenes ACETAMIDE AND BENZAMIDE FOR THE PRODUCTION OF ANTI-SPRACTS.
FR2674849B1 (en) * 1991-04-02 1994-12-23 Logeais Labor Jacques NOVEL N-CYCLOHEXYL BENZAMIDES OR THIOBENZAMIDES DERIVATIVES, THEIR PREPARATIONS AND THEIR THERAPEUTIC APPLICATIONS.
AU3192295A (en) * 1994-08-11 1996-03-07 Yamanouchi Pharmaceutical Co., Ltd. Substituted amine derivative and medicinal composition containing the same
FR2735693B1 (en) * 1995-06-23 1997-09-26 Logeais Labor Jacques NEW THERAPEUTIC APPLICATIONS OF N-CYCLOHEXYL BENZAMIDES

Also Published As

Publication number Publication date
AR014901A1 (en) 2001-04-11
FR2766486B1 (en) 1999-09-17
FR2766486A1 (en) 1999-01-29
WO1999005133A1 (en) 1999-02-04
CO4990983A1 (en) 2000-12-26
EP0998469A1 (en) 2000-05-10
ZA986632B (en) 1999-02-04
AU8867998A (en) 1999-02-16

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