CO4990983A1 - CYCLLOALKYL BENZAMIDES STIMULATING HIGH AND LOW GASTROINTESTINAL MOTRICITY - Google Patents
CYCLLOALKYL BENZAMIDES STIMULATING HIGH AND LOW GASTROINTESTINAL MOTRICITYInfo
- Publication number
- CO4990983A1 CO4990983A1 CO98042279A CO98042279A CO4990983A1 CO 4990983 A1 CO4990983 A1 CO 4990983A1 CO 98042279 A CO98042279 A CO 98042279A CO 98042279 A CO98042279 A CO 98042279A CO 4990983 A1 CO4990983 A1 CO 4990983A1
- Authority
- CO
- Colombia
- Prior art keywords
- alkyl group
- branched
- linear
- cyclloalkyl
- motricity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Compuestos de fórmula general 1:Caracterizado porque:- R1 es un grupo alquilo linear, ramificado o ciclizado en C1 a C6 o un grupo cicloalquilo en C3 a C6 , dicho grupo alquilo pudiendo, dado el caso, formar un ciclo de 4 a 5 átomos de carbono en el ciclo, en asociación con el carbono en posición 3 del ciclo aromático, y con el cual portan el átomo de oxígeno. - R2 es H, un grupo alquilo en C1 a C6 , lineal o ramificado, OH, o un grupo hidroxialquílico, en el cual el grupo alquilo está en C1 a C4 lineal o ramificado. - R3 es H, un grupo alquilo en C1 a C6 lineal o ramificado, OH o un grupo de hidroxialquilico en el cual el grupo alquilo está en C1 a C4 linear o ramificado, bajo reserva que R2 y R3 no puedan representar simultáneamente a OH. -m = 1 ó 2; -n = 1, 2 ó 3.Compounds of general formula 1: Characterized in that: - R1 is a linear, branched or cyclized alkyl group at C1 to C6 or a cycloalkyl group at C3 to C6, said alkyl group being able, if appropriate, to form a cycle of 4 to 5 atoms carbon in the cycle, in association with carbon in position 3 of the aromatic cycle, and with which they carry the oxygen atom. - R2 is H, a linear or branched C1 to C6 alkyl group, OH, or a hydroxyalkyl group, in which the alkyl group is linear or branched C1 to C4. - R3 is H, a linear or branched C1 to C6 alkyl group, OH or a hydroxyalkyl group in which the linear or branched C1 to C4 alkyl group, subject to the fact that R2 and R3 cannot simultaneously represent OH. -m = 1 or 2; -n = 1, 2 or 3.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9709478A FR2766486B1 (en) | 1997-07-25 | 1997-07-25 | HIGH AND LOW GASTROINTESTINAL MOTOR STIMULATING BENZAMIDE CYCLOALKYLES |
Publications (1)
Publication Number | Publication Date |
---|---|
CO4990983A1 true CO4990983A1 (en) | 2000-12-26 |
Family
ID=9509624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO98042279A CO4990983A1 (en) | 1997-07-25 | 1998-07-24 | CYCLLOALKYL BENZAMIDES STIMULATING HIGH AND LOW GASTROINTESTINAL MOTRICITY |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0998469A1 (en) |
AR (1) | AR014901A1 (en) |
AU (1) | AU8867998A (en) |
CO (1) | CO4990983A1 (en) |
FR (1) | FR2766486B1 (en) |
TN (1) | TNSN98137A1 (en) |
WO (1) | WO1999005133A1 (en) |
ZA (1) | ZA986632B (en) |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1015921A (en) * | 1961-10-06 | 1966-01-05 | Benger Lab Ltd | Benzamides |
AR216043A1 (en) * | 1974-03-21 | 1979-11-30 | Anphar Sa | PROCEDURE FOR THE PREPARATION OF 1-BENZOYLAMINE-4-PIPERIDINE DERIVATIVES AND ITS PHYSIOLOGICALLY ACCEPTABLE SALTS |
EP0222533A1 (en) * | 1985-10-25 | 1987-05-20 | The Upjohn Company | Cis-N-[(2-aminocycloaliphatic)benzene acetamide and -benzamide anticonvulsants |
FR2674849B1 (en) * | 1991-04-02 | 1994-12-23 | Logeais Labor Jacques | NOVEL N-CYCLOHEXYL BENZAMIDES OR THIOBENZAMIDES DERIVATIVES, THEIR PREPARATIONS AND THEIR THERAPEUTIC APPLICATIONS. |
WO1996005166A1 (en) * | 1994-08-11 | 1996-02-22 | Yamanouchi Pharmaceutical Co., Ltd. | Substituted amine derivative and medicinal composition containing the same |
FR2735693B1 (en) * | 1995-06-23 | 1997-09-26 | Logeais Labor Jacques | NEW THERAPEUTIC APPLICATIONS OF N-CYCLOHEXYL BENZAMIDES |
-
1997
- 1997-07-25 FR FR9709478A patent/FR2766486B1/en not_active Expired - Fee Related
-
1998
- 1998-07-15 TN TNTNSN98137A patent/TNSN98137A1/en unknown
- 1998-07-24 AU AU88679/98A patent/AU8867998A/en not_active Abandoned
- 1998-07-24 AR ARP980103646A patent/AR014901A1/en not_active Application Discontinuation
- 1998-07-24 EP EP98940330A patent/EP0998469A1/en not_active Withdrawn
- 1998-07-24 ZA ZA986632A patent/ZA986632B/en unknown
- 1998-07-24 CO CO98042279A patent/CO4990983A1/en unknown
- 1998-07-24 WO PCT/FR1998/001641 patent/WO1999005133A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU8867998A (en) | 1999-02-16 |
ZA986632B (en) | 1999-02-04 |
TNSN98137A1 (en) | 2005-03-15 |
FR2766486A1 (en) | 1999-01-29 |
AR014901A1 (en) | 2001-04-11 |
EP0998469A1 (en) | 2000-05-10 |
FR2766486B1 (en) | 1999-09-17 |
WO1999005133A1 (en) | 1999-02-04 |
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