TNSN98063A1 - Methode de fabrication du sertindole - Google Patents
Methode de fabrication du sertindoleInfo
- Publication number
- TNSN98063A1 TNSN98063A1 TNTNSN98063A TNSN98063A TNSN98063A1 TN SN98063 A1 TNSN98063 A1 TN SN98063A1 TN TNSN98063 A TNTNSN98063 A TN TNSN98063A TN SN98063 A TNSN98063 A TN SN98063A TN SN98063 A1 TNSN98063 A1 TN SN98063A1
- Authority
- TN
- Tunisia
- Prior art keywords
- indole
- fluorophenyl
- obtaining
- sertindole
- chlorophenyle
- Prior art date
Links
- GZKLJWGUPQBVJQ-UHFFFAOYSA-N sertindole Chemical compound C1=CC(F)=CC=C1N1C2=CC=C(Cl)C=C2C(C2CCN(CCN3C(NCC3)=O)CC2)=C1 GZKLJWGUPQBVJQ-UHFFFAOYSA-N 0.000 title abstract 3
- 229960000652 sertindole Drugs 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 4
- -1 4 -FLUOROPHENYL Chemical class 0.000 abstract 3
- 239000004471 Glycine Substances 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- CIRSPTXGPFAXRE-UHFFFAOYSA-N 3-(1,2,3,6-tetrahydropyridin-4-yl)-1h-indole Chemical compound C1NCCC(C=2C3=CC=CC=C3NC=2)=C1 CIRSPTXGPFAXRE-UHFFFAOYSA-N 0.000 abstract 1
- JYEKQDWSLSXYTJ-UHFFFAOYSA-N 5-chloro-1-(4-fluorophenyl)indole Chemical compound C1=CC(F)=CC=C1N1C2=CC=C(Cl)C=C2C=C1 JYEKQDWSLSXYTJ-UHFFFAOYSA-N 0.000 abstract 1
- CVICEEPAFUYBJG-UHFFFAOYSA-N 5-chloro-2,2-difluoro-1,3-benzodioxole Chemical compound C1=C(Cl)C=C2OC(F)(F)OC2=C1 CVICEEPAFUYBJG-UHFFFAOYSA-N 0.000 abstract 1
- JBOPQACSHPPKEP-UHFFFAOYSA-N Indoxyl acetate Chemical compound C1=CC=C2C(OC(=O)C)=CNC2=C1 JBOPQACSHPPKEP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK53697 | 1997-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN98063A1 true TNSN98063A1 (fr) | 2005-03-15 |
Family
ID=8094655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN98063A TNSN98063A1 (fr) | 1997-05-09 | 1998-05-08 | Methode de fabrication du sertindole |
Country Status (13)
| Country | Link |
|---|---|
| AR (1) | AR012661A1 (instruction) |
| CA (1) | CA2486883C (instruction) |
| CO (1) | CO4950521A1 (instruction) |
| DZ (1) | DZ2483A1 (instruction) |
| IL (1) | IL156180A0 (instruction) |
| IN (3) | IN187834B (instruction) |
| JO (1) | JO2015B1 (instruction) |
| MA (1) | MA25584A1 (instruction) |
| MY (1) | MY124162A (instruction) |
| PE (1) | PE73199A1 (instruction) |
| TN (1) | TNSN98063A1 (instruction) |
| TW (1) | TW487692B (instruction) |
| ZA (1) | ZA983726B (instruction) |
-
1998
- 1998-04-27 MY MYPI9801885 patent/MY124162A/en unknown
- 1998-05-01 IN IN948MA1998 patent/IN187834B/en unknown
- 1998-05-04 ZA ZA983726A patent/ZA983726B/xx unknown
- 1998-05-04 CO CO98024289A patent/CO4950521A1/es unknown
- 1998-05-05 DZ DZ980094A patent/DZ2483A1/xx active
- 1998-05-05 AR ARP980102090 patent/AR012661A1/es active IP Right Grant
- 1998-05-07 JO JO19982015A patent/JO2015B1/en active
- 1998-05-07 CA CA002486883A patent/CA2486883C/en not_active Expired - Fee Related
- 1998-05-07 IL IL15618098A patent/IL156180A0/xx not_active IP Right Cessation
- 1998-05-08 TN TNTNSN98063A patent/TNSN98063A1/fr unknown
- 1998-05-08 PE PE00035498A patent/PE73199A1/es not_active Application Discontinuation
- 1998-05-11 MA MA25070A patent/MA25584A1/fr unknown
- 1998-07-02 TW TW87110712A patent/TW487692B/zh not_active IP Right Cessation
-
2000
- 2000-09-08 IN IN777MA2000 patent/IN190902B/en unknown
- 2000-09-18 IN IN776MA2000 patent/IN192270B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY124162A (en) | 2006-06-30 |
| PE73199A1 (es) | 1999-08-09 |
| MA25584A1 (fr) | 2002-12-31 |
| JO2015B1 (en) | 1999-05-15 |
| IN187834B (instruction) | 2002-06-29 |
| CA2486883C (en) | 2009-04-28 |
| CA2486883A1 (en) | 1998-11-19 |
| DZ2483A1 (fr) | 2004-09-05 |
| CO4950521A1 (es) | 2000-09-01 |
| AR012661A1 (es) | 2000-11-08 |
| IN192270B (instruction) | 2004-03-27 |
| TW487692B (en) | 2002-05-21 |
| IL156180A0 (en) | 2003-12-23 |
| ZA983726B (en) | 1998-11-24 |
| IN190902B (instruction) | 2003-08-30 |
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