TNSN86161A1 - Nouvelles anthracyclines et medicaments les contenant - Google Patents

Nouvelles anthracyclines et medicaments les contenant

Info

Publication number
TNSN86161A1
TNSN86161A1 TNTNSN86161A TNSN86161A TNSN86161A1 TN SN86161 A1 TNSN86161 A1 TN SN86161A1 TN TNSN86161 A TNTNSN86161 A TN TNSN86161A TN SN86161 A TNSN86161 A TN SN86161A TN SN86161 A1 TNSN86161 A1 TN SN86161A1
Authority
TN
Tunisia
Prior art keywords
image
case
hydrogen atom
different
proviso
Prior art date
Application number
TNTNSN86161A
Other languages
English (en)
Inventor
Jean-Pierre Gesson
Martine Mondon
Jean-Claude Jacquesy
Hans Peter Kraemer
Original Assignee
Hoechst Sa Lab
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Sa Lab, Behringwerke Ag filed Critical Hoechst Sa Lab
Publication of TNSN86161A1 publication Critical patent/TNSN86161A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA PRESENTE INVENTION EST RELATIVE A DE NOUVELLES ANTHRACYCLINES CORRESPONDANT A LA FORMULE GENERALE I CI APRES , DANS LAQUELLE R' ET R'' QUI PEUVENT ETRE IDENTIQUES OU DIFFERENTS, REPRESENTENT UN ATOME D'HYDROGENE (ET DANS CE CAS R' EST DIFFERENT DE R'') OU LE GROUPE -(CH2)N-R1-(CH2)-M- R2, OU N EST COMPRIS ENTRE 1 ET 6, M EST COMPRIS ENTRE 0 ET 4 (AVEC, BIEN ENTENDU, LA CONDITION QUE SI M = 0, R2 EST NUL) R1 REPRESENTE UN DES GROUPES SUIVANTS. (DANS CE CAS M=0 OU R3 ET R4 IDENTIQUES OU DIFFERENTS REPRESENTENT UN ATOME D'HYDROGENE OU UN GROUPE ALKYLE SUBSTITUE OU NON). (DANS CE CAS M=0 AVEC LA CONDITION QUE M SOIT DIFFERENT DE 0). (M=0 ET R3 ET R4 ONT LA MEME SIGNIFICATION QUE CI-DESSUS). ET R2 REPRESENTE (DANS LE CAS OU M EST DIFFERENT DE 0) UN ATOME D'HYDROGENE OU LES GROUPES ALKYLE, ALCOXY OU (R3 ET R4 AYANT LA MEME SIGNIFICATION QUE CI-DESSUS)
TNTNSN86161A 1985-12-17 1986-12-17 Nouvelles anthracyclines et medicaments les contenant TNSN86161A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8518661A FR2591599B1 (fr) 1985-12-17 1985-12-17 Nouvelles anthracyclines et medicaments les contenant

Publications (1)

Publication Number Publication Date
TNSN86161A1 true TNSN86161A1 (fr) 1990-01-01

Family

ID=9325860

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN86161A TNSN86161A1 (fr) 1985-12-17 1986-12-17 Nouvelles anthracyclines et medicaments les contenant

Country Status (10)

Country Link
US (1) US4789665A (fr)
EP (1) EP0226173B1 (fr)
JP (1) JPS62155292A (fr)
AT (1) ATE51002T1 (fr)
AU (1) AU598499B2 (fr)
DE (1) DE3669514D1 (fr)
DK (1) DK606286A (fr)
FR (1) FR2591599B1 (fr)
MA (1) MA20829A1 (fr)
TN (1) TNSN86161A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3819092A1 (de) * 1988-06-04 1989-12-14 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
JP2779652B2 (ja) * 1988-12-27 1998-07-23 武田薬品工業株式会社 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物
DE3913743A1 (de) * 1989-04-26 1990-10-31 Behringwerke Ag Zytostatisch wirksame rhodomycinderivate
DE3913742A1 (de) * 1989-04-26 1990-10-31 Behringwerke Ag Zytostatisch wirksame rhodomycinderivate
US5196522A (en) * 1990-11-01 1993-03-23 Board Of Regents, The University Of Texas System Anthracycline analogues bearing latent alkylating substituents
GB9114549D0 (en) * 1991-07-05 1991-08-21 Erba Carlo Spa Mono and bis alkylamino-anthracyclines

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260736A (en) * 1978-08-14 1981-04-07 Kureha Kagaku Kogyo Kabushiki Kaisha Steroid hormone-antitumor derivatives
GR79729B (fr) * 1982-12-20 1984-10-31 Univ Ohio State Res Found
PL138836B1 (en) * 1983-07-08 1986-11-29 Politechnika Gdanska Process for preparing novel n-substituted derivatives of anthracycline antibiotics
US4591637A (en) * 1985-01-17 1986-05-27 Sri International Open chain-morpholino adriamycins
GB2182926B (en) * 1985-11-19 1989-10-04 Erba Farmitalia Nitro anthracyclines, process for their preparation and use thereof
GB8617742D0 (en) * 1986-07-21 1986-08-28 Erba Farmitalia 6-amino anthracyclines

Also Published As

Publication number Publication date
FR2591599B1 (fr) 1988-08-05
DK606286D0 (da) 1986-12-16
JPS62155292A (ja) 1987-07-10
FR2591599A1 (fr) 1987-06-19
EP0226173B1 (fr) 1990-03-14
DK606286A (da) 1987-06-18
AU598499B2 (en) 1990-06-28
MA20829A1 (fr) 1987-07-01
ATE51002T1 (de) 1990-03-15
AU6658486A (en) 1987-06-18
DE3669514D1 (de) 1990-04-19
US4789665A (en) 1988-12-06
EP0226173A1 (fr) 1987-06-24

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