TNSN05095A1 - Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof - Google Patents

Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof

Info

Publication number
TNSN05095A1
TNSN05095A1 TNP2005000095A TNSN05095A TNSN05095A1 TN SN05095 A1 TNSN05095 A1 TN SN05095A1 TN P2005000095 A TNP2005000095 A TN P2005000095A TN SN05095 A TNSN05095 A TN SN05095A TN SN05095 A1 TNSN05095 A1 TN SN05095A1
Authority
TN
Tunisia
Prior art keywords
conjugates
methods
preparation
compositions
polymer conjugates
Prior art date
Application number
TNP2005000095A
Inventor
Alexa L Martinez
Merry R Sherman
Mark G P Saifer
L David Williams
Original Assignee
Mountain View Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2003/029989 external-priority patent/WO2004030617A2/en
Application filed by Mountain View Pharmaceuticals Inc filed Critical Mountain View Pharmaceuticals Inc
Publication of TNSN05095A1 publication Critical patent/TNSN05095A1/en

Links

Abstract

Methods are provided for the preparation of conjugates of a viariety of bioactive components, especially proteins, with water-soluble polymers (e.g., poly ( ethylene glycol) and derivatives thereof), with conjugates have reduced antigenicity and immunogenicity compared to similar conjugates prepared using poly (ethylene glycol) containing a methoxyl or another alkoxyl group. The invention also provides conjugates prepared by such methods, compositions comprising such conjugates, kits containing such conjugates or compositions and methods of use of the conjugates and compositions in diagnostic and therapeutic protocols.
TNP2005000095A 2002-09-30 2005-03-28 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof TNSN05095A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41442402P 2002-09-30 2002-09-30
PCT/US2003/029989 WO2004030617A2 (en) 2002-09-30 2003-09-25 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof

Publications (1)

Publication Number Publication Date
TNSN05095A1 true TNSN05095A1 (en) 2007-05-14

Family

ID=50557599

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2005000095A TNSN05095A1 (en) 2002-09-30 2005-03-28 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof

Country Status (2)

Country Link
TN (1) TNSN05095A1 (en)
UA (1) UA86002C2 (en)

Also Published As

Publication number Publication date
UA86002C2 (en) 2009-03-25

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