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Priority claimed from PCT/EP2011/063504external-prioritypatent/WO2012019967A1/en
Application filed by Sanofi SafiledCriticalSanofi Sa
Publication of TN2013000054A1publicationCriticalpatent/TN2013000054A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
The invention relates to a process for the preparation of the enantiomeric forms of 2,3-diaminopropionic acid derivatives of formula (I), wherein R1, R2 and R3 are defined as in the claims, by racemate resolution. The separation of the racemate into its enantiomers takes place through formation of diastereomeric salts upon addition of an enantiomerically pure auxiliary, and subsequent separation by fractional crystallization.
TNP2013000054A2011-08-052013-02-11Process for the preparation of enantiomeric forms of 2,3 - diaminopropionic acid derivatives
TN2013000054A1
(en)
Process for preparation of optically pure and optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives and their use in preparing pharmaceuticals