NI201300022A -
PROCEDURE FOR PREPARING ENANTIOMERIC FORMS OF DERIVATIVES OF 2,3-DIAMINOPROPIONIC ACID
- Google Patents
PROCEDURE FOR PREPARING ENANTIOMERIC FORMS OF DERIVATIVES OF 2,3-DIAMINOPROPIONIC ACID
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Publication number
NI201300022A
NI201300022ANI201300022ANI201300022ANI201300022ANI 201300022 ANI201300022 ANI 201300022ANI 201300022 ANI201300022 ANI 201300022ANI 201300022 ANI201300022 ANI 201300022ANI 201300022 ANI201300022 ANI 201300022A
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Application filed by Sanofi SafiledCriticalSanofi Sa
Publication of NI201300022ApublicationCriticalpatent/NI201300022A/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
La invención se refiere a un procedimiento para preparar las formas enantioméricas de derivados de ácido 2, 3 - diaminopropiónico de fórmula (I), en donde R1, R2 y R3 están definidos como en las reivindicaciones, por resolución de racemato. La separación del racemato en sus enantiómeros tiene lugar a través de la formación de sales diastereómeras al añadir un auxiliar enantioméricamente puro, y la separación subsiguiente mediante cristalización fraccionada.The invention relates to a process for preparing the enantiomeric forms of 2, 3-diaminopropionic acid derivatives of formula (I), in which R1, R2 and R3 are defined as in the claims, by resolution of the racemate. The separation of the racemate into its enantiomers takes place through the formation of diastereomeric salts by adding an enantiomerically pure auxiliary, and the subsequent separation by fractional crystallization.
NI201300022A2010-08-122013-02-08
PROCEDURE FOR PREPARING ENANTIOMERIC FORMS OF DERIVATIVES OF 2,3-DIAMINOPROPIONIC ACID
NI201300022A
(en)
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SOLID SALTS AND FORMS OF (S) -3- (4 - ((4- (MORFOLINOMETIL) BENCIL) OXI) -1-OXOISOINDOLIN-2-IL) PIPERIDIN-2, 6-DIONA AND COMPOSITIONS THAT INCLUDE AND METHODS TO USE THE SAME
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