TH98239B - Microorganisms that produce O-acetyl-homoserine and methods for producing O-acetyl-homoserine using this microorganism. - Google Patents

Abstract

DC60 (01/04/53) Disclosed herein are microbial strains that can produce O-acetyl homoserine, a precursor of L-methionine, in high yields and methods of O-acetyl homoserine production using this microbial strain. The microbial strain is Escherichia sp. in which the gene acetyl-CoA synthase (acs) and/or gene pentothenate kinase (coaA) encoding a gene pentothenate kinase resistant to CoA feedback inhibition is introduced and expressed. Disclosed herein are microbial strains that can produce O-acetyl homoserine, a precursor of L-methionine, in high yields. and the method for the production of O-acetyl homoserine using this microbial strain. This microbial strain is Escherichia sp. in which the gene acetyl-CoA synthase (acs) and/or gene pentothenate kinase (coaA) that encodes a gene pentothenate kinase resistant to feedback inhibition by CoA is introduced and expressed.

Claims (3)

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