TH96578B - Pyrolotriacine kinase inhibitors - Google Patents
Pyrolotriacine kinase inhibitorsInfo
- Publication number
- TH96578B TH96578B TH701003415A TH0701003415A TH96578B TH 96578 B TH96578 B TH 96578B TH 701003415 A TH701003415 A TH 701003415A TH 0701003415 A TH0701003415 A TH 0701003415A TH 96578 B TH96578 B TH 96578B
- Authority
- TH
- Thailand
- Prior art keywords
- alkyl
- substituted
- pyrolotriacine
- kinase inhibitors
- formula
- Prior art date
Links
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 4
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000001589 carboacyl group Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 125000001188 haloalkyl group Chemical group 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 150000002431 hydrogen Chemical group 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 206010001897 Alzheimer's disease Diseases 0.000 abstract 1
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้ให้สารประกอบตามสูตร l (สูตรเคมี) (l) และเกลือซึ่งเป็นที่ยอมรับทางเภสัชกรรมของสารนี้ สารประกอบสูตร l นี้ ยับยั้งไทโรซีนไคเนสแอกติวิตี้ ซึ่งดังนั้นจะทำให้สารเหล่านี้ มีประโยชน์ในการเป็นสารต้านมะเร็ง และสำหรับการรักษาโรคอัลไซเมอร์ This invention provides a compound based on the formula l (chemical formula) (l) and a chemically acceptable salt of this substance. This l compound inhibits tyrosine kinase activity. Which will therefore make these substances Useful as an anti-cancer agent And for the treatment of Alzheimer's disease
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH96578A TH96578A (en) | 2009-07-09 |
| TH96578B true TH96578B (en) | 2009-07-09 |
Family
ID=
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